LOCUS       NZ_CP043317            21137 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Streptomyces olivaceus strain SCSIO T05 chromosome, complete genome.
ACCESSION   NZ_CP043317
VERSION     NZ_CP043317.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces olivaceus
  ORGANISM  Streptomyces olivaceus
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8458055)
  AUTHORS   Zhang,C., Ding,W., Qin,X. and Ju,J.
  TITLE     Genome Sequencing of Streptomyces olivaceus SCSIO T05 and Activated
            Production of Lobophorin CR4 via Metabolic Engineering and Genome
            Mining
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8458055)
  AUTHORS   Zhang,C., Ding,W., Qin,X. and Ju,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2019) Key Laboratory of Tropical Marine
            Bio-resources and Ecology, South China Sea Institute of Oceanology,
            Chinese Academy of Science, NO.164 Xingang Road, Guangzhou,
            Guangdong 510301, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 28-MAR-2017
            Assembly Method                   :: HGAP v. MAR-2017
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 8458055.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015244315.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 18:39:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,352
            CDSs (total)                      :: 7,265
            Genes (coding)                    :: 7,077
            CDSs (with protein)               :: 7,077
            Genes (RNA)                       :: 87
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 188
            CDSs (without protein)            :: 188
            Pseudo Genes (ambiguous residues) :: 0 of 188
            Pseudo Genes (frameshifted)       :: 106 of 188
            Pseudo Genes (incomplete)         :: 98 of 188
            Pseudo Genes (internal stop)      :: 7 of 188
            Pseudo Genes (multiple problems)  :: 23 of 188
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:52:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7959694
            Orig. end                         :: 7980831
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP043317.1.
            Bacteria and source DNA available from South China Sea Institute of
            Oceanology, Chinese Academy of Science; 164 West Xingang Road,
            Guangzhou 510301, China.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21137
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="indole"
                     /region_number="36"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /tool="antismash"
     cand_cluster    1..21137
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21137
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11137](+)"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11137
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
     gene            135..1604
                     /db_xref="GeneID:69765279"
                     /locus_tag="FYC74_RS34570"
     CDS             135..1604
                     /codon_start=1
                     /db_xref="GeneID:69765279"
                     /gene_functions="transport (smcogs) SMCOG1169: sugar
                     transport protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019324207.1"
                     /locus_tag="FYC74_RS34570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sialate:H+ symport family MFS transporter"
                     /protein_id="WP_194279003.1"
                     /transl_table=11
                     /translation="MSSARTTTKPRPWYREITRQKWKSFFAAWIGYLLDGFDFVLITLV
                     LTEIADDFGLSTVESASLVSGAFITRWLGGAVLGALGDRFGRRSAMVASILLYSVGTFA
                     CGFAWDYTSLFTARLLIGMGMAGEYSASATYVLESWPARLRNRASGFLISGFSLGGVLA
                     AEVYEHVVPGHGWRWLFYIGLFPVVVALWVRRSLPEADDWEARVGATGERPNPFRPLFA
                     GRRRASVNTVLAVVATGSLFAVFTPLGAGAVPVLSVVATACLVAFAVQLGGRRRWLLFV
                     ALCATVFCAFLYSWPVQALLPTYLKTELGFTPAQVSDALYYAGFGTMAGCIVTGFVGDR
                     FGTRRAYACTLAVGIAFVFPVFAIRDSQLQLGILLFLMLACMQGISGLLPKYIAGHFPT
                     ETRAASLGFTYNVGALGGAVAPVLGARLASSMSLGQSLAVLTFSLTLVVILLIGFDVPS
                     RLNRLVDPEAVPDYLATEAAADGAPSVPSAK"
     gene            1707..2072
                     /db_xref="GeneID:69765280"
                     /locus_tag="FYC74_RS34575"
     CDS             1707..2072
                     /codon_start=1
                     /db_xref="GeneID:69765280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004992805.1"
                     /locus_tag="FYC74_RS34575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transglycosylase family protein"
                     /protein_id="WP_194279004.1"
                     /transl_table=11
                     /translation="MICRRNALQGNARRPHGRTIRTAVAALLAAAALAATTGAAASPSV
                     SLRTDWDSIAACESGGDWQANTGNGYYGGLQFAPSSWAAAGGLKYAPRADLATRAEQIA
                     VAKRLAGLQGMSAWGCA"
     gene            complement(2318..3154)
                     /db_xref="GeneID:69765281"
                     /locus_tag="FYC74_RS34580"
     CDS             complement(2318..3154)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69765281"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971683.1"
                     /locus_tag="FYC74_RS34580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_194279005.1"
                     /transl_table=11
                     /translation="MTGRTASSPTPDHDDAVLRLQDVSVRRLTTDQLILDGVDWSVRPG
                     EHWALLGANGAGKTTLLRLLGALMHPTTGTVEVLGSRLGRVDVRELRARIGHVNSAQRV
                     PQDLTAHAVVLTGHSGTVQPLWRTYDDGVRERARGLLTELGVKELADRPYGVCSGGQRA
                     RILIARALMADPALLLLDEPFNALDLPSREDLVEAMHQLTEGRPRLATVTVTHHLEELF
                     PAVSHTLLLREGRILSRGPVDDVLTDDLLTACFGREITVARRDGRWSAYSGRRTRG"
     misc_feature    complement(3195..3213)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.64"
                     /tool="antismash"
     gene            complement(3290..4648)
                     /db_xref="GeneID:69765282"
                     /locus_tag="FYC74_RS34585"
     CDS             complement(3290..4648)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69765282"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639923.1"
                     /locus_tag="FYC74_RS34585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_194279006.1"
                     /sec_met_domain="p450 (E-value: 1.7e-77, bitscore: 259.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLVAPPPIPRAAGSLPFLGHAVQLMRDNLGFVAALRTTYGPLVE
                     ITLQPGTRTLVVQDPGLIRTMLTDLGPSLDKGRFFEKMGQLLGDSVVTAAGQVHVRKRR
                     QLQPAFAREQIARYVDTMRAETDAAVDDWVPGRPLDVREAMVGLSLNMLAKTIFSGSLD
                     DATFRRLRADLSIVMNGVGARVMLPDWVERLPLPANRRFNSARDGVRATIERAVSDLQD
                     SGHDTGDMLSLLLRTTDEETGEPLTGHQISSEILTLAVAGTETTASVLSWMLYELARNP
                     EIGARVLEELDEVLGDRPVAFDDLGRLPYLGRVVEETLRMHHTGWLVTRRTVTETRLGP
                     WTVPPGTELAYCQHALHRDPLLFRDPLEFDPDRWLDDPGPRPTQGFLPFGAGKHKCIGD
                     RFAFTELVTAVATIVRRVRLELAPGQTVRPVAAATVRPRTLLMTVREKEGQGA"
     misc_feature    complement(4697..4712)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: medium, score: 27.25"
                     /tool="antismash"
     gene            complement(4829..5581)
                     /db_xref="GeneID:69765283"
                     /locus_tag="FYC74_RS34590"
     CDS             complement(4829..5581)
                     /codon_start=1
                     /db_xref="GeneID:69765283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018104742.1"
                     /locus_tag="FYC74_RS34590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_194279007.1"
                     /transl_table=11
                     /translation="MAAVFAAGVGAGAINSVVGSGTLITFPVLLATGLSPVTATVSNAL
                     GLIPGSISGAIGYRKELTGQRRRVLKLGAGALLGGLAGATLLLSLPPDAFETIVPVLVG
                     LALVLVAFQPQIGRLVQRRRERTGASPRRDGGPLLLVGLTLASVYGGYFTAAQGIIYLS
                     LMGMLLDEPMQRLNGVKNVLSAVVNTVAALFFLFAADFDWTAVGLLAVGSALGGWFGAK
                     VGRRFSPLVLRILVVTVGAVALAQLLLR"
     misc_feature    5719..5728
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.82"
                     /tool="antismash"
     gene            5913..7094
                     /db_xref="GeneID:69765284"
                     /locus_tag="FYC74_RS34595"
     CDS             5913..7094
                     /codon_start=1
                     /db_xref="GeneID:69765284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971679.1"
                     /locus_tag="FYC74_RS34595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_194279008.1"
                     /transl_table=11
                     /translation="MTEYTANPLLWVLLVALVAAAVLVSRQRRAARALRQQVQGLRDRY
                     TQLENNYGKSVQAAQERAEDETKTVLKSAMRTLQGLAAEQQLVLSRLQSKYGESALLED
                     LLEIDHTNSQFGRRAQSVAVLCDGWLGGRRDTASVYDVVRSAQGRIRHFRRVDILSRVD
                     FGITSRAVEPVALALAELLDNATSYSSPDTVVEINIRTVPKGICVVVDDAGVGMSDEER
                     ARADKLLATERASGVAALGNPPQFGFAVIGLLCERFGFEVSVDSSSPYGGVRAVVLLPH
                     DMLTAMPEKKAPAPADRPTARPVPDGGPEAAPAASRTDDGLPRRRRKRPMAIVPGSASA
                     PRPTGRSDSEQARVMGAFQRGTRSGRGTEPENAENADRTSSTPGASSEGHEVS"
     gene            7091..7492
                     /db_xref="GeneID:69765285"
                     /locus_tag="FYC74_RS34600"
     CDS             7091..7492
                     /codon_start=1
                     /db_xref="GeneID:69765285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971678.1"
                     /locus_tag="FYC74_RS34600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_031032694.1"
                     /transl_table=11
                     /translation="MNDDLSWMLDSALEIPGALHAVLISADGLLMARTQDFDKDDADRV
                     AAAMSGVQSLSRTLSFFCEDPGQNWRQTLVEFDGGWVFLISAGEGAYLGVSASPEVDMA
                     DITFRMQQLVAQLGKRLTTPPRENLGARS"
     gene            7489..7866
                     /db_xref="GeneID:69765286"
                     /locus_tag="FYC74_RS34605"
     CDS             7489..7866
                     /codon_start=1
                     /db_xref="GeneID:69765286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971677.1"
                     /locus_tag="FYC74_RS34605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_194279009.1"
                     /transl_table=11
                     /translation="MTGRDGWTPESAALVRPYVITKGRNLPDEDALSLLTLVTASAEDA
                     RRPARLSPEEQSLLDLCSAGYLSVAEIAGHTHFPLGVVRILLASLMEGGYLLTRPPVAR
                     ARLADREILEEVLNGLRAKFG"
     misc_feature    7528..7530
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7841..8431
                     /db_xref="GeneID:69765287"
                     /locus_tag="FYC74_RS34610"
     CDS             7841..8431
                     /codon_start=1
                     /db_xref="GeneID:69765287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005331.1"
                     /locus_tag="FYC74_RS34610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_037770300.1"
                     /transl_table=11
                     /translation="MGSAPSLDERDYVREGATQTAVKILVVGHFAVGKTTLIGSISEIE
                     PLSTEETMTQAAEPVDDLKGVKGKTTTTVAMDFGRLTISDRIVLYLFGTPGQQRFVQMW
                     EDMARGALGALVLVDPERLADSFPVIDLIEHYGLDYAIAVNHFDGAPARDERALREALD
                     LLDDTPVVTCDARDEKSSAAALTTLVRHLLDRA"
     misc_feature    8443..8454
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: strong, score: 20.58"
                     /tool="antismash"
     gene            8447..9793
                     /db_xref="GeneID:69765288"
                     /locus_tag="FYC74_RS34615"
     CDS             8447..9793
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69765288"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972616.1"
                     /locus_tag="FYC74_RS34615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_194279010.1"
                     /transl_table=11
                     /translation="MNAHDPAPVPPPGCPAHGSGARVPLHGPEFAADPQAYYEYLRHYG
                     AAAPVELAPGVEATLVTDYTAALQLLQDSGSFRKDARRWRAFNEGKVSPDSPVAPLLAY
                     RPNCMFADGADHLRLRQAVTDSMARVDTRRLSRSTEQISRYLISQFAARGSADLLGDYA
                     KQLPLFVFNELFGCPADIGDRVLFGISGMFDGVNAEKATEVLFQAVGELVALKREKPGD
                     DVTSWLMRHEAGLDDEEMVHQLALLLGAGAEPLRNLIGNTLHRLLTHERYAREGGLIDE
                     ALDDTLWENPPMSNYAPHYPAADTEFAGQQLQAGDLVLVSFAAANTGPALKASRQAGSN
                     RAHLAWSAGPHACPSKEPARHITVTAIEHLLNELPDVALAVPEDSLAWRPGPFNRALAT
                     LPARFTPVRSVRRTEPRPAPAAEQEKAAAPARPAERAGMWSQFLNWLTR"
     misc_feature    9862..9875
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.73"
                     /tool="antismash"
     misc_feature    complement(9990..10005)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            10001..11137
                     /db_xref="GeneID:69765289"
                     /locus_tag="FYC74_RS34620"
     CDS             10001..11137
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_process="GO:0009820 - alkaloid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69765289"
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indole_PTase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971675.1"
                     /locus_tag="FYC74_RS34620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tryptophan dimethylallyltransferase family
                     protein"
                     /protein_id="WP_194279011.1"
                     /sec_met_domain="indole_PTase (E-value: 4e-143, bitscore:
                     475.4, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAAPTGADPRGTPTLGALTGGQLRRLAAVAGLSATDTAAYVRVL
                     TDSLGPVAARPLSLPPPTRTFLSDDHTPVEYSLSFRPDAAPALRVLLEPGCGADSLARN
                     GRVGLEAVRRMARRWHFATDALDEIEDLFLPFGPQGPLALWCALELRPGGVPGVKVYLN
                     PAANGAERSAATVREALHRLGHRRAFAALPQGAGYPFLALDLGEWAQPRVKVYVRHDNL
                     TAGRAGRLSRTDRGPGPAAIEGFFRAAAALGPDVAGLGRRPALSCHSFTDTAAVRPSGF
                     TLHIPVRDYVRHDGEALARAARVLRHHGMDPSVLVRALAAVTGRRLEDGAGLVAYLALA
                     HQQGHPPRVTAYLSAEAYAVRPAVGGSAPTAMPAMPVG"
     gene            complement(11215..12513)
                     /db_xref="GeneID:69765290"
                     /locus_tag="FYC74_RS34625"
     CDS             complement(11215..12513)
                     /EC_number="1.14.13.-"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69765290"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FMO-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1092: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971674.1"
                     /locus_tag="FYC74_RS34625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_194279012.1"
                     /sec_met_domain="FMO-like (E-value: 2.8e-78, bitscore:
                     262.4, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Pyr_redox_2 (E-value: 8.8e-10, bitscore:
                     37.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVCVIGAGLSGLAVAHALKERGIPFVCLEKAPDVGGIWRQPGAG
                     ERGPGYLSLHLNTAKQLTGYADFPMPSSYPLYPRHSQFAAYLRSFAEWAGLLGHVELRT
                     EAVSVRQDADGGWTVVSRDADGAEVSRRFEQVVVASGHHTDPALPDPLPAGADSFTGTI
                     LHSLDYRDGGDFDGRRVVVVGLGASAVDIAADLSRHAEQTLLSVRRGLHIVPKQLFGMS
                     VDEIAEAPWWTEMSFAEQRRWVERALLVARGRLGDYGLPEPDHPVFSSATTLSDEILSR
                     IRHGAVTPKPAIGSFDGDRVVFTDGTCVTADAVVYCTGFRMTFPFLPTGCPVAADGSVE
                     LYRRVVPADRPGLYFVGLVRPVGSITRLVEAQAQWVARLVDGEAELPAAGKMREEISTY
                     LAGIVQRYGRAPGASVQVDVGPYLAEFRESLPV"
     gene            complement(12623..13969)
                     /db_xref="GeneID:69765291"
                     /gene="paaK"
                     /locus_tag="FYC74_RS34630"
     CDS             complement(12623..13969)
                     /EC_number="6.2.1.30"
                     /GO_function="GO:0047475 - phenylacetate-CoA ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (101-352). E-value: 4.9e-20.
                     Score: 63.4. Matches aSDomain:
                     nrpspksdomains_FYC74_RS34630_AMP-binding.1"
                     /codon_start=1
                     /db_xref="GeneID:69765291"
                     /gene="paaK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971673.1"
                     /locus_tag="FYC74_RS34630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phenylacetate--CoA ligase PaaK"
                     /protein_id="WP_194279013.1"
                     /sec_met_domain="AMP-binding (E-value: 5.2e-25, bitscore:
                     86.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSEPTTGAAPATRRGEPLPHDLLDDAERLSSEQLQELQLDRLRA
                     TLRHAYDNVELYRKKFDAAGVVPDDCRSLADLSRFPFTTKADLRETYPFGMFAVPMADV
                     RRVHASSGTTGRATVVGYTDNDLSAWADVVARSIRAAGGRPGHKVHVSYGYGLFTGGLG
                     AHYGAERAGCTVIPASGGMTARQVQIIQDFRPEIIMVTPSYMLTLLDEFERQGVDPRTT
                     SLQVGIFGAEPWTEEMRREIEERAGIHAVDIYGLSEVMGPGVAQECVETKDGLHVWEDH
                     FYPEVVDPLTDAVLPGGEEGELVFTSLTKEALPVVRYRTRDLSRLLPGTARPAFRRMSK
                     VTGRCDDMIILRGVNVFPTQIEEIVLRTPGVAPHFQIRLTARGRMDHLTVRVEARPDAG
                     PEQREAAARAIGQSVKDGVGVSVEVEIVDPETLERSLGKLHRVKDLRTA"
     CDS_motif       complement(12884..12946)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FYC74_RS34630_0001"
                     /evalue="2.60E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="FYC74_RS34630"
                     /protein_end="362"
                     /protein_start="341"
                     /score="13.8"
                     /tool="antismash"
                     /translation="TGRCDDMIILRGVNVFPTQIE"
     aSDomain        complement(12914..13666)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FYC74_RS34630_AMP-binding.1"
                     /evalue="4.90E-20"
                     /label="FYC74_RS34630_AMP-binding.1"
                     /locus_tag="FYC74_RS34630"
                     /protein_end="352"
                     /protein_start="101"
                     /score="63.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ADVRRVHASSGTTGRATVVGYTDNDLSAWADVVARSIRAAGGRPG
                     HKVHVSYGYGLFTGGLGAHYGAERAGCTVIPASGGMTARQVQIIQDFRPEIIMVTPSYM
                     LTLLDEFERQGVDPRTTSLQVGIFGAEPWTEEMRREIEERAGIHAVDIYGLSEVMGPGV
                     AQECVETKDGLHVWEDHFYPEVVDPLTDAVLPGGEEGELVFTSLTKEALPVVRYRTRDL
                     SRLLPGTARPAFRRMSKVTGRCDDMIILR"
     gene            complement(<14122..14487)
                     /db_xref="GeneID:96997548"
                     /gene="paaI"
                     /locus_tag="FYC74_RS37525"
                     /pseudo=""
     CDS             complement(<14122..14487)
                     /GO_function="GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96997548"
                     /gene="paaI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010043931.1"
                     /locus_tag="FYC74_RS37525"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hydroxyphenylacetyl-CoA thioesterase PaaI"
                     /pseudo=""
                     /transl_table=11
                     /translation="MFAADRASRGLGIELVEQGAGSAVVRMTVTPAMVNGHRIAHGGFL
                     FLLADTAFACACNSHGPVTVAAGADIVFVAPAREGDVLVARAEERARYGRSGIYDVSVR
                     RGDEVIAEFRGRSRSARG"
     misc_feature    complement(14560..14575)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 22.17"
                     /tool="antismash"
     misc_feature    complement(14682..14695)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.77"
                     /tool="antismash"
     gene            14714..15700
                     /db_xref="GeneID:69765293"
                     /gene="paaA"
                     /locus_tag="FYC74_RS34640"
     CDS             14714..15700
                     /GO_function="GO:0097266 - phenylacetyl-CoA 1,2-epoxidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69765293"
                     /gene="paaA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004003132.1"
                     /locus_tag="FYC74_RS34640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaA"
                     /protein_id="WP_194279014.1"
                     /transl_table=11
                     /translation="MTTTHAAEAPPPQEPDGLQEHFDATVARDQRVEPRDWMPDGYRKT
                     LIRQIAQHAHSEIIGMQPEGEWITRAPSLRRKAILFAKVQDEAGHGLYLYSAAETLGAD
                     RDDLTERLIEGRQKYSSIFNYPTLSFADVGVIGWFVDGAAICNQVPLCRSSYGPYARAM
                     VRICKEESFHQRQGYELLMTMMRGTPAQREMVQDAVDRWWWPSLMMFGPPDDASPNSAR
                     SMAWKIKRHSNDELRRRFVDMTVPQAEKLGVTLPDPELRWNEEAGHHDFGTPDWDELTR
                     VIKGDGPCNAQRTERRRTAHEEGAWVREAATAHAAKQAARTQKGAAV"
     gene            15697..15999
                     /db_xref="GeneID:69765294"
                     /gene="paaB"
                     /locus_tag="FYC74_RS34645"
     CDS             15697..15999
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69765294"
                     /gene="paaB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007388027.1"
                     /locus_tag="FYC74_RS34645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaB"
                     /protein_id="WP_194279015.1"
                     /transl_table=11
                     /translation="MSADRPERQGWPLYEVFVRGKRGLNHVHVGSLRAADDAMALTHAR
                     DLYTRRNEGVSIWVVRSEHIAASTRDEKDPFFAPSADKVYRHPTFYDIPDDVPHI"
     gene            16009..16836
                     /db_xref="GeneID:69765295"
                     /gene="paaC"
                     /locus_tag="FYC74_RS34650"
     CDS             16009..16836
                     /EC_number="1.14.13.149"
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69765295"
                     /gene="paaC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009326306.1"
                     /locus_tag="FYC74_RS34650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaC"
                     /protein_id="WP_194279016.1"
                     /transl_table=11
                     /translation="MSDDHVYLTLAEGHEDDTRWAYGTGFEDPLHGVDTTVPEGVDAAG
                     LAAECVALADDALVGAQRLAEWITRAPELEEEVALANIGLDLLGQARLLYTRAGQADGT
                     GRDEDAYAYFRDAADFRNVTLAELPGGDFAFTVVRLLVLSSWRLAHFRGLVDHPDPVLA
                     AVAAKGVKELTYHRQYAAQWCVRLGDGTDESHRRMRVALEQVAPYLGELHTAHDVRDEV
                     AADLRQVTDAAGLPLPVYRPLPGSGRAGEHTEHLAPLLTELQGIARAHPEATW"
     gene            16830..17345
                     /db_xref="GeneID:69765296"
                     /gene="paaD"
                     /locus_tag="FYC74_RS34655"
     CDS             16830..17345
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69765296"
                     /gene="paaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007388025.1"
                     /locus_tag="FYC74_RS34655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaD"
                     /protein_id="WP_194279017.1"
                     /transl_table=11
                     /translation="MVTAGPALPDAHRARRVAERVPDPELPMLTLADLGVLRDVETRAD
                     GTVVASLTPTYSGCPAMAEMRADVAARLRAAGYARVEIRTVLDPPWTSDWITESGRRKL
                     AEHGIAPPGRAPRGPVPLLLSPTRPAVPCPRCGSRETEETSRFAATSCKALWRCRACRE
                     PFEYVKEI"
     gene            17345..18451
                     /db_xref="GeneID:69765297"
                     /gene="paaE"
                     /locus_tag="FYC74_RS34660"
     CDS             17345..18451
                     /EC_number="1.14.13.149"
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69765297"
                     /gene="paaE"
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007388024.1"
                     /locus_tag="FYC74_RS34660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaE"
                     /protein_id="WP_194279018.1"
                     /transl_table=11
                     /translation="MAPTAPVPAAPARARRRPAFHRLRVAAVERLCADAVAVRFEVPDE
                     LAGAYAFAPGQSLTLRREVDGRDERRSYSICVAAGSAPRIGVRVVPGGLFSAWLVDEVR
                     PGDTVEVMTPTGLFTPDLTVPGHHVLIAAGSGITPMVSIAESVLAADDRSTVTLFYGNR
                     RTGTVMFADELADLKDLHPARFQLAHVLSREPREAELLSGRLDAERLTALVGSLVDVEA
                     AGHWWLCGPQGMVADAQQVLAGLGVPADRVHRELFFAGDEPVREVHHEEGGPRGPVSEV
                     TVTLDGRSTTASLSRERSILDGAQQTRPDLPFACKGGVCGTCRALVTDGKADMRRNYAL
                     EAAEVDAGYVLTCQSYPVSEQLTVDYDS"
     gene            18736..20214
                     /db_xref="GeneID:69765298"
                     /locus_tag="FYC74_RS34665"
     CDS             18736..20214
                     /codon_start=1
                     /db_xref="GeneID:69765298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018894182.1"
                     /locus_tag="FYC74_RS34665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_382499459.1"
                     /transl_table=11
                     /translation="MTTPDAPTHATGAMHRRSRPAVVAAALAAVFLGTLGNVSAAPARA
                     AVEPTAGQPVAADCPPALAEKATCYTGQDENGAYYTMAVPHRWNGSLVVHAHGGPDLGD
                     TSDPARSTEDLGRWAVMVDEGYAWAGSSYRRGGYGARMAAADTENVRRLFTDRFGRPER
                     TYLHGQSWGGNVAAKVAETYGGRPGAYDGVLLTNGVLGGGSRGYDYRVDLRVVYQYYCH
                     NHPRPTEPQYPLWQGLRAGSTMTTAGLRARLQECTGYASDPADRTGPQQRNLDDILAVT
                     GIPERTLESHLRFATFTFRDIVANRLDGRNPWSNRGVRYTGSHDDKALNAGVERFSADP
                     TARRDLSYDSDLTGRVSLPVLTMHAIDDPTAFVEHEAAYRATLRGAGRGGNLVQTFTKE
                     HEHSSLSDSEYANSMAALDTWVSTGRRPSPRAIAASCADFDATYGDGCFYDPGFRPAPY
                     ASRVLPRPGGLTWPAMTAARERAWSSIQGVGIAP"
     gene            complement(20276..20839)
                     /db_xref="GeneID:69765299"
                     /locus_tag="FYC74_RS34670"
     CDS             complement(20276..20839)
                     /codon_start=1
                     /db_xref="GeneID:69765299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031691.1"
                     /locus_tag="FYC74_RS34670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tellurite resistance TerB family protein"
                     /protein_id="WP_031032661.1"
                     /transl_table=11
                     /translation="MAMWDKIKDQAKTFQQSQGTRGASGSGQGAQASGRPGSSGGSKTQ
                     LIGMFKSQLASVKTELKSGSYRDASMAMCALVAAADGHVEPAERTRVEELIVSNEVLQN
                     FPADQLRQRFNQHVDRLLANVEQGRSEALQVIAKASKKPEEARAVIQTGMVVAGADGVF
                     EPSEQQAIREACSALGISPAEFGV"
     misc_feature    20986..21006
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 19.32"
                     /tool="antismash"
ORIGIN
        1 ccgtggcccg ggtccgcgac cggctcaccg aggccggtct cctgtgaccc gcggaccggg
       61 gccgcaggcc cggccccggt cctgcccgct ccccgtcccc gacgcgcgaa tccgcacccc
      121 gcattggacc cgtcatgtca tctgcgcgca ccaccacgaa gccccgcccc tggtacagag
      181 agatcacccg gcagaagtgg aagtccttct tcgccgcctg gatcggctat ctcctcgacg
      241 gcttcgactt cgtcctcatc accctcgtac tgaccgagat cgccgacgac ttcggactgt
      301 cgaccgtcga gtccgcgagc ctggtgtccg gtgcgttcat cacccgctgg ctcggcggcg
      361 ccgtgctcgg cgcgctcggc gaccgcttcg gccgcaggag cgccatggtg gccagcatcc
      421 tgctgtactc ggtcggcacc ttcgcctgcg gcttcgcctg ggactacacc agcctgttca
      481 ccgcgcgcct gctgatcggc atgggcatgg ccggcgagta cagcgccagc gccacctacg
      541 tactggagag ctggcccgcc cggctgcgca accgcgcctc cggattcctc atctccggct
      601 tctcgctggg cggcgtgctg gcggccgagg tctacgagca cgtggtgccg ggacacggct
      661 ggcgctggct gttctacatc gggctgttcc cggtggtcgt cgccctgtgg gtgcggcggt
      721 cgctgcccga ggccgacgac tgggaggccc gggtgggggc caccggcgag cggcccaacc
      781 ccttccgccc gctgttcgcg gggcggcgcc gggcgagcgt caacacggtg ctggcggtgg
      841 tcgccaccgg ctcgctgttc gcggtgttca ccccgctcgg cgccggtgcg gtgcccgtcc
      901 tgtccgtggt ggcgacggcc tgcctcgtcg ccttcgcggt ccagctgggc gggcgcagga
      961 ggtggctgct gttcgtggcg ctctgcgcca ccgtgttctg cgccttcctc tacagctggc
     1021 cggtccaggc cctgctgccc acctacctca agaccgaact gggcttcacc cccgcccagg
     1081 tcagcgacgc gctctactac gccgggttcg gcacgatggc gggctgcatc gtcaccgggt
     1141 tcgtcggcga ccggttcggc acccgccggg cgtacgcgtg cacgctggcg gtcgggatcg
     1201 ccttcgtctt ccccgtcttc gcgatccgcg acagccaact gcagctcggc atcctgctgt
     1261 tcctgatgct cgcctgcatg cagggcatct cggggctgct gccgaagtac atcgccgggc
     1321 acttcccgac cgagacccgg gccgcgtccc tgggcttcac ctacaacgtc ggtgcgctgg
     1381 gcggcgccgt cgcgccggtg ctcggggcca ggctggcctc ctccatgtcg ctcggccagt
     1441 cgcttgcggt gctgaccttc tcgctgacac tcgtggtcat cctgctgatc gggttcgacg
     1501 tgcccagccg cctcaaccgg ctggtcgacc cggaggccgt gccggactac ctcgccacgg
     1561 aggcggcggc ggacggcgcg ccgtccgtgc cgtcggcgaa gtgacgcgga ctccacggcg
     1621 aacagggtgg ttcgggtgct ccgaccggcg tagggcggcg ccgggcgggg cggcggcccg
     1681 ccctcacgtg gggtaacagt ccaagtatga tctgtagacg aaatgctctt cagggcaacg
     1741 cgcgccgtcc gcacggtcgc acgatccgga ccgccgtggc cgctctcctc gccgcggccg
     1801 cactcgccgc gaccaccggg gcggccgcct ccccgtcggt ttcgctgcgc acggactggg
     1861 actccatcgc tgcctgcgag tcgggcggcg actggcaggc gaacaccggc aacggctact
     1921 acgggggcct gcagttcgcc ccgtcgagct gggccgcggc cggcggcctg aagtacgccc
     1981 cgcgcgcgga cctcgcgacc cgcgccgagc agatcgccgt cgcgaagcgt ctggccggcc
     2041 tgcagggaat gtcggcctgg ggctgcgcct gagaccgcgg cccgggacgt cccgggccga
     2101 ggtctgcgct cgacggggac gcgtgttgac cggggtcacc cgcgggcgtg aaccgggccc
     2161 ggcctccgcg gcgttccgtt tgtccggagc gccgattggg cagtccccgg cgggggagcc
     2221 gaggggcggc cccggacgtt ccgcacgccg acacgtccgg gaccgctccg ccctttcgga
     2281 cggcggcgga cgacggcgga cgacggcggc ggtggggcta accccgggtg cgccggccgg
     2341 agtaggccga ccagcggccg tcgcgcctgg cgaccgtgat ctcgcggccg aagcaggcgg
     2401 tcagcaggtc gtccgtgagg acgtcgtcca ccggcccccg ggacaggatc cggccctcgc
     2461 gcagcagcag ggtgtggctg acggccggga acagctcctc caggtggtgg gtgaccgtca
     2521 ccgtggccag ccgggggcgc ccctcggtca gctggtgcat cgcctcgacg aggtcctccc
     2581 gggacggcag gtccagggcg ttgaagggct cgtccaggag gagcagcgcc gggtcggcca
     2641 tcagcgccct ggcgatgagg atccgcgccc gctgaccgcc cgagcagacg ccgtagggcc
     2701 ggtccgccag ctccttgacg cccagctcgg tcagcaggcc gcgggcccgc tcccgcaccc
     2761 cgtcgtcgta cgttcgccac aggggctgga ccgtgccgct gtggccggtc agcacgaccg
     2821 cgtgcgcggt gaggtcctgc ggcacccgct gggcggagtt cacatggccg atgcgcgccc
     2881 gcagctcccg cacgtcgacc cggccgagcc ggctgccgag cacctcgacc gtgccggtcg
     2941 tggggtgcat gagcgcgccg agcagccgca gcagggtcgt cttcccggcg ccgttggccc
     3001 ccagcagggc ccagtgctcg cccgggcgga ccgaccagtc gacgccgtcc aggatcagct
     3061 ggtccgtggt gaggcggcgg acgctcacgt cctggagccg gagtacggcg tcgtcgtggt
     3121 cgggcgtggg ggagctggcg gtccggccgg tcatgccgtg actccttcgt acgggacgtc
     3181 ctcggtcacc gtgcacagta gatgtatcca ccacatgcct gccggaccgt ccggttcctg
     3241 gacgcccggc cgctgccgct ctcttctccc ctgttctccc ctctgcttcc tatgccccct
     3301 gcccctcctt ctcgcggacg gtcatcagca gggtgcgggg ccggaccgtg gccgcggcga
     3361 cggggcgcac cgtctggccg ggcgcgagct ccagccgtac ccgccgcacg atggtggcga
     3421 cggcggtgac gagttcggtg aacgcgaacc ggtcgccgat gcacttgtgc ttgccggcgc
     3481 cgaagggcag gaacccctga gtgggccgcg gccccgggtc gtccagccag cggtcggggt
     3541 cgaactccag cgggtcgcgg aacagcagcg ggtcgcggtg cagggcgtgc tggcagtagg
     3601 cgagttcggt gccggggggc accgtccagg ggccgagccg ggtctcggtg acggtgcgcc
     3661 gggtgacgag ccacccggtg tggtgcatcc gcagcgtctc ctccaccacc cggcccaggt
     3721 acggcagccg gccgaggtcg tcgaaggcca ccggccggtc gccgaggacc tcgtcgagct
     3781 cctccaggac ccgcgccccg atctccgggt tgcgggcgag ttcgtacagc atccaggaca
     3841 ggaccgaggc ggtggtctcg gtgccggcga cggccagggt gaggatctcg gaggagatct
     3901 ggtggccggt cagcggctct ccggtctcct cgtcggtggt gcgcagcagc agcgagagca
     3961 tgtcaccggt gtcgtggccg gagtcctgga ggtcgctcac ggcgcgttcg atggtggccc
     4021 gcacgccgtc gcgcgccgag ttgaagcggc ggttggcggg cagcgggagc cgctcgaccc
     4081 agtcgggcag catgacgcgg gcgcccacgc cgttcatcac gatcgacagg tcggcgcgca
     4141 gccggcggaa cgtggcgtcg tcgagactgc ccgagaagat cgtcttggcc agcatgttca
     4201 ggctgagccc gaccatggcc tcgcggacgt ccagcggccg gccggggacc cagtcgtcga
     4261 cggcggcgtc cgtctcggcg cgcatggtgt cgacgtaccg ggcgatctgc tcgcgggcga
     4321 aggcgggctg cagctggcgc ctcttgcgga cgtggacctg gccggccgcg gtgacgacgg
     4381 agtcgccgag gagctgtccc atcttctcga agaaccggcc cttgtcgagg ctcggtccca
     4441 ggtcggtcag catggtgcgg atgaggccgg gatcctgcac gacgagggtg cgggtgccgg
     4501 gctggagggt gatctcgacc agggggccgt aggtggtgcg cagcgcggcg acgaagccga
     4561 ggttgtcgcg catgagctgt accgcgtggc ccaggaacgg cagcgaaccc gctgccctgg
     4621 gtatgggggg aggcgctacg agcgtcacgg tggggtatgt cccttcgcat cgatcatggg
     4681 cgctccatgg cttccctgat cgctaccggc gtcaatcggc cacggaacgt ggcatttccc
     4741 acgtgtcccg gatggccgga aatgattggc cggggaggcg gttgggcaga ttccactccc
     4801 gcccgccccc gacaccggtg gcccctggct agcgcagcag cagctgcgcc agggcgaccg
     4861 cgccgaccgt caccaccagt atccgcagaa ccagggggct gaaacgtcgg cccaccttgg
     4921 cgccgaacca gccacccagg gccgagccga ccgcgagcag tccgacggcg gtccagtcga
     4981 agtccgcggc gaagaggaag aagagggcgg cgacggtgtt gacgacggcg gagaggacgt
     5041 tcttgacgcc gttgaggcgt tgcatgggtt cgtcgaggag catgcccatc agggacaggt
     5101 agatgatccc ctgggcggcg gtgaagtagc cgccgtagac gctggcgagg gtcaggccga
     5161 cgaggagcag cggaccgccg tcccggcggg gagaggcacc ggtgcgctcc cggcggcgct
     5221 gcaccagccg gccgatctgc ggctggaacg ccaccagcac cagggcgagt cccaccagta
     5281 ccggcacgat cgtctcgaag gcgtccggcg gcagcgacag cagcagggtg gcgcccgcca
     5341 ggccgccgag cagggccccg gcgcccagct tcaggacgcg ccggcgctgg ccggtcagct
     5401 ccttgcggta gccgatggca ccgctgatgg agccggggat cagacccagc gcgttggaca
     5461 ccgtcgcggt caccggcgac agtcccgtgg ccagcagtac ggggaaggtg atcagggttc
     5521 cggagccgac gacgctgttg atggcgccgg ctccgacgcc cgccgcgaag accgcggcca
     5581 tggcctcggg cgtcaccccg tgccgccgcg cgccgggccc gtactcagcc ggaacgtgcc
     5641 ttgtgcgtct ttcacgggcc cgactgtacc caccgctccg gcgggcccgg tccccggtct
     5701 caaccggtcc gtgatgggcg ttctttgacg ttaattcacc tgatcatgcg gtgatacgat
     5761 caccgcgttt gcagagcggg cggatgggtg aaagacggca tccccgactt cagggacagc
     5821 ccgggcggcc acccgggcgc cggcggtccg ccggaccgcc cgcgtggacc ggaacgcagc
     5881 aaaccggccg taagtcgcct gaagagagtc ttatgacgga atacacggca aacccattgc
     5941 tctgggtcct gctcgtcgcc ctcgtcgccg ccgccgtgct cgtcagccgc cagcgcaggg
     6001 cggcccgggc gttgcggcag caggtccagg ggctcaggga ccgctacacc cagctggaga
     6061 acaactacgg gaaatccgtg caggccgctc aggagcgggc cgaggacgag acgaagaccg
     6121 tgctgaaatc ggccatgcgg actctccagg gcctcgccgc cgaacagcag ctggtgctct
     6181 cccggctgca gagcaagtac ggcgaatcgg ccctgctcga ggacctgctg gagatcgacc
     6241 acaccaactc gcagttcggc cggcgcgcgc agtccgtcgc ggtcctgtgc gacggctggc
     6301 tgggcggccg gcgcgacacc gcctcggtgt acgacgtggt ccgcagcgcg cagggacgca
     6361 tccggcactt ccgccgggtg gacatcctct cccgggtcga cttcggcatc accagccgcg
     6421 ccgtcgagcc cgtcgcgctg gccctcgccg aactgctcga caacgccacc agctactcca
     6481 gcccggacac cgtcgtggag atcaacatcc gcaccgtgcc caagggcatc tgcgtggtcg
     6541 tggacgacgc cggcgtcggc atgagcgacg aggaacgggc gcgcgccgac aagctgctcg
     6601 ccaccgagcg cgcctcgggc gtggcggctc tcggcaaccc gccgcagttc ggcttcgccg
     6661 tcatcggcct gctgtgcgag cgcttcgggt tcgaggtgtc ggtggactcc tcctctccct
     6721 acggaggcgt acgggcggtg gttctgctgc cgcacgacat gctcaccgcc atgcccgaga
     6781 agaaggcgcc cgcaccggcc gaccgcccca ccgcccggcc ggtcccggac ggcggaccgg
     6841 aggccgcgcc cgccgcctcc cggaccgacg acggtctgcc ccggcggcgc cgcaagcggc
     6901 cgatggccat cgtgcccggc agcgcctccg ccccgcgccc caccggacgc tccgactccg
     6961 agcaggcccg ggtcatgggc gccttccagc gcggaacgcg ctccggccgg ggcaccgagc
     7021 cggagaacgc cgagaacgcc gaccggacga gcagcacacc tggtgcaagc agtgaaggac
     7081 atgaggtctc gtgaacgacg atctgtcatg gatgctcgac agcgccctgg agattccggg
     7141 ggccctgcac gcggtcctga tatccgccga cggcctgctg atggcccgga cgcaggactt
     7201 cgacaaggac gacgccgacc gggtggccgc cgcgatgagc ggtgtgcagt cgctcagccg
     7261 caccctctcc ttcttctgtg aggacccggg ccagaactgg cgccagaccc tcgtcgagtt
     7321 cgacggcggc tgggtcttcc tgatctccgc cggcgagggc gcctacctcg gcgtctccgc
     7381 ctccccggag gtggacatgg ccgacatcac cttccgcatg cagcaactcg tcgcccagct
     7441 cggcaagcgg ctgacgacac cgccgcgcga gaacctcggc gcccgctcat gaccggccgc
     7501 gacggctgga cgcccgagtc cgccgcatta gtacgtccgt acgtcatcac caagggccgc
     7561 aacctgcccg acgaggacgc cctctcgctc ctcaccctgg tcaccgcgtc cgccgaggac
     7621 gcgcggcggc ccgcccggct ctcccccgag gagcagagcc tgctcgacct gtgttccgcc
     7681 ggctacctct cggtcgccga gatcgccggg cacacccact tcccgctggg cgtggtgcgg
     7741 atcctgctgg cgtccctgat ggagggcggg tacctcctga cccgtccgcc ggtggcccgc
     7801 gcccgcctcg cggacaggga gatcctggag gaggtgctca atgggctccg cgccaagttt
     7861 ggatgagcgg gactacgtgc gcgagggagc gacccagacc gcggtcaaga tcctcgtcgt
     7921 cggccacttc gcggtgggca agaccaccct catcggctcc atctccgaga tcgagccgct
     7981 gtccaccgag gagacgatga cgcaggccgc cgagccggtc gacgacctca agggtgtgaa
     8041 gggcaagacc accaccacgg tcgccatgga cttcggccgc ctcaccatca gcgaccgcat
     8101 cgtgctctac ctgttcggca cccccggcca gcagcgtttc gtgcagatgt gggaggacat
     8161 ggcccgcggc gcgctcggcg ccctcgtcct ggtcgacccc gagcggctcg cggactcctt
     8221 cccggtgatc gacctcatcg agcactacgg actcgactac gccatcgccg tcaaccactt
     8281 cgacggcgcg ccggcgcgcg acgaacgggc gctgcgcgag gcgctcgacc tgctcgacga
     8341 cacccccgtc gtcacctgcg acgcccgcga cgagaagtcc tcggccgccg cactgaccac
     8401 cctcgtccgc catctgctcg acagagccta ggagccggaa gcagacatga acgcccacga
     8461 ccccgcgccg gtgccgccgc ccggctgccc ggcccacgga tccggcgccc gggtgccgtt
     8521 gcacggaccg gagttcgctg ccgacccgca ggcgtactac gagtacctgc gccactacgg
     8581 ggccgcggcc cccgtcgagc tggcccccgg cgtcgaggcc acgctggtca cggactacac
     8641 ggcggcgctc cagctgctgc aggactccgg ttcgttccgc aaggacgccc gccgctggcg
     8701 ggccttcaac gagggcaagg tgagcccgga cagcccggtc gcgcccctgc tcgcgtaccg
     8761 gcccaactgc atgttcgccg acggcgccga ccacctcagg ctccgccagg ccgtcaccga
     8821 cagcatggcg cgggtcgaca cccggcggct gagccggagc accgagcaga tctcccgcta
     8881 cctcatctcg cagttcgccg cccgcggctc cgccgaccta ctcggggact acgccaagca
     8941 gttgccgctg ttcgtgttca acgaactctt cggctgcccc gccgacatcg gggaccgggt
     9001 gctgttcggc atctccggca tgttcgacgg agtgaacgcc gagaaggcca ccgaggtgct
     9061 cttccaggcg gtcggggaac tcgtggcgct caagcgggag aagcccggtg acgacgtcac
     9121 ctcctggctg atgcgccacg aggcggggct cgacgacgag gagatggtcc accagctcgc
     9181 cctgctcctc ggcgcgggcg ccgaacccct gcgcaacctc atcggcaaca ccctgcaccg
     9241 gctcctcacc catgagcggt acgcccgtga gggaggcctg atcgacgagg cgctcgacga
     9301 cacgctgtgg gagaacccgc cgatgtccaa ctacgccccg cactacccgg ccgccgacac
     9361 ggagttcgcc ggtcagcagc tccaggcggg cgacctcgtc ctggtgagct tcgccgcggc
     9421 caacaccggg ccggccctca aggcctcgcg ccaggccggc agcaaccggg cccacctggc
     9481 ctggagcgcg ggtccgcacg cctgcccctc caaggagccg gcccggcaca tcaccgtcac
     9541 ggccatcgag cacctgctca acgaactgcc cgacgtcgcg ctcgccgtcc ccgaggacag
     9601 cctggcctgg cgtccgggcc ccttcaaccg tgccctggcc acgctcccgg ccaggttcac
     9661 ccccgtccgc tccgtgcggc gcaccgagcc ccgcccggct ccggcggccg agcaggagaa
     9721 ggcggccgcc ccggcccgtc cggccgagcg cgcaggcatg tggagccagt tcctcaactg
     9781 gctcacgcgg tgacctccgc aacatctccc caacccgcac ccctcgcatg aagtttgaac
     9841 ggcacgggta gtgagcaacg cggcattcaa gttgcttacg agtaaaagga ggtgtcgtgg
     9901 accacatatc cacgaacgcc gctttccggc cgcagagaac cccgataccc gcctcgccag
     9961 gcgggtatcg ctttgtccgg ctccgaccgg ggacgggccg gtgaccgccg caccgacggg
    10021 cgccgatccg cggggcacac cgacgctcgg ggccctcacg ggcgggcagt tgcgaaggct
    10081 cgcggccgtc gccggactct ccgcgacgga caccgcggcc tacgtccggg tgctgaccga
    10141 ctcgctgggc ccggtggccg cacggccgtt gagtctgcct ccgcccaccc gtaccttcct
    10201 ctccgacgac cacacccccg tcgagtactc cctctccttc cggcccgacg cggcgcccgc
    10261 cctgcgggtg ctcctggaac cgggctgcgg cgcagacagc ctggcccgca acggccgcgt
    10321 cggactggag gcggtgcggc ggatggcgcg acgctggcac ttcgccaccg acgcactgga
    10381 cgagatcgag gacctgttcc tgcccttcgg tccccagggg ccgctggccc tgtggtgcgc
    10441 gctggagctc agacccggcg gtgtacccgg cgtcaaggtc tatctgaacc cggcggccaa
    10501 cggggcggaa cgttccgccg cgacggtgcg cgaggcgctg caccggctcg gccaccggcg
    10561 ggccttcgcc gccctgcccc agggtgccgg gtacccgttc ctcgccctgg acctggggga
    10621 gtgggcgcag ccccgggtga aggtctacgt gcggcacgac aacctcacgg cggggcgggc
    10681 cgggcggctg tcccgaacgg accggggccc ggggcccgcc gcgatcgagg ggttcttccg
    10741 cgccgccgcg gccctcggtc ccgacgtggc gggcctcggc cggcggcccg ccctgtcctg
    10801 ccactccttc accgacaccg ccgccgtccg gccgagcggc ttcaccctgc acatccccgt
    10861 ccgggactac gtccgccacg acggggaggc cctcgcgcgg gcggcgcgcg tgctgcggca
    10921 ccacggcatg gacccctcgg tcctcgtccg cgccctggcc gccgtcaccg gacggcgcct
    10981 cgaggacggc gcgggactcg tcgcctacct ggcgctggcc caccagcagg gccacccgcc
    11041 gcgggtgacc gcttacctct ccgcggaggc gtacgcggtc aggcccgcgg tcggcgggag
    11101 cgctcccacg gcgatgccgg cgatgccggt gggctgagcg ggcccgtccg gacacggcag
    11161 ggctcccggt ggacgccacc gggagcccga gcggtgaagc gcgccgcggt cccgctacac
    11221 gggcagggac tcccggaact ccgccaggta cggacccacg tcgacctgga cggaggcgcc
    11281 cggcgcccgg ccgtaccgct ggacgatgcc ggcgaggtac gtggagatct cctcgcgcat
    11341 ctttccggcg gccggcagtt ccgcctcgcc gtcgacgagc cgcgccaccc actgggcctg
    11401 ggcctccacc agccgggtga tcgagcccac cgggcggacc agacccacga agtacagacc
    11461 cggacggtcg gccgggacga ccctgcggta cagctcgacc gagccgtccg ccgccaccgg
    11521 gcagcccgtc ggcaggaagg ggaaggtcat gcggaagccg gtgcagtaga cgaccgcgtc
    11581 cgcggtcacg caggtgccgt cggtgaagac gacccggtcg ccgtcgaacg agccgatcgc
    11641 gggcttcggc gtcacggcgc cgtgccggat ccggctgagg atctcgtccg agagggtggt
    11701 cgcggacgag aacaccgggt ggtccggctc gggcagaccg tagtccccga gtctgccgcg
    11761 ggcgacgagc agggcccgct ccacccaccg gcgctgctcg gcgaaggaca tctcggtcca
    11821 ccacggggcc tcggcgatct cgtcgaccga catcccgaag agctgcttgg gcacgatgtg
    11881 cagcccgcgt cgcaccgaca gcagggtctg ctcggcgtgc cgggagaggt ccgccgcgat
    11941 gtccaccgcc gacgcgccga ggcccaccac gacgacgcgg cggccgtcga agtcgccgcc
    12001 gtcgcggtag tcgagcgagt gcagaatcgt tccggtgaag gagtcggcgc cggccggcag
    12061 ggggtcgggc agggccgggt cggtgtggtg gccggaggcg acgaccacct gctcgaaccg
    12121 gcgcgagacc tcggcgccgt ccgcgtcccg gctgacgacc gtccacccgc cgtccgcgtc
    12181 ctggcgcacc gagaccgcct cggtgcgcag ctcgacgtgg ccgagcaggc cggcccactc
    12241 ggcgaaggag cgcaggtagg cggcgaactg gctgtgccgg gggtagagcg gatacgagga
    12301 cggcatcggg aagtccgcgt aaccggtcag ctgcttggcg gtgttgaggt gcagcgacag
    12361 atagcccggc ccccgctcgc cggcccccgg ctgacgccag atcccgccga cgtccggcgc
    12421 cttctccagg cagacgaacg ggatgccgcg ctccttgagg gcgtgcgcca ccgccagccc
    12481 cgacaggcct gcaccgatca cacacacgcg cacgggattc cccccagaaa gctcaaacct
    12541 cccccgatca tggacttcct gcccatccgt accgactcgc acaccggacc gaggagcgaa
    12601 caggcgtgtc cgtcctcacg tttcacgccg tgcgcaggtc cttgacccgg tggagtttgc
    12661 ccagggagcg ctccagcgtc tccgggtcca cgatctccac ctccacgctc acgcccacac
    12721 cgtccttgac gctctgtccg atcgcccggg cggcggcctc gcgctgctcg ggacccgcgt
    12781 cggggcgggc ctccacgcgt acggtcaggt ggtccatgcg gccgcgcgcg gtgagccgga
    12841 tctggaagtg cggggccacg ccgggcgtgc gtagcacgat ctcctcgatc tgggtgggga
    12901 agacgttcac gccgcgcagg atgatcatgt cgtcgcagcg gccggtgacc ttgctcatcc
    12961 gccggaaggc ggggcgggcg gtgcccggca gcagccgtga caggtcgcgc gtgcggtagc
    13021 ggacgacggg cagcgcctcc ttggtcaggg aggtgaagac tagctccccc tcctcgcccc
    13081 cgggcagtac ggcgtccgtg agcgggtcga ccacctcggg gtagaagtgg tcctcccaca
    13141 cgtgcagtcc gtccttggtc tcgacgcact cctgggccac gcccgggccc atcacctcgg
    13201 acaggccgta gatgtcgacg gcgtggatgc ccgcccgctc ctcgatctcg cgccgcatct
    13261 cctcggtcca cggctccgcg ccgaagatgc cgacctggag ggaggtggtg cgcgggtcga
    13321 cgccctgccg ttcgaactcg tcgagcaggg tgagcatgta ggacggcgtg accatgatga
    13381 tctcgggccg gaagtcctgg atgatctgca cctggcgtgc cgtcatcccg ccggaggcgg
    13441 ggatcacggt gcaaccggcg cgttcggcgc cgtagtgcgc gccgaggccg ccggtgaaca
    13501 ggccgtagcc gtaggagacg tgcaccttgt ggccgggccg gccgccggcg gcccggatcg
    13561 agcgggcgac gacgtccgcc cacgccgaca ggtcgttgtc cgtgtatccg accacggtgg
    13621 cgcggccggt ggtgccgctg gaggcgtgca cgcgccgtac gtcggccatc ggaacggcga
    13681 acatcccgaa ggggtaggtc tcccgcagat cggccttggt ggtgaagggg aaccgcgaca
    13741 ggtccgccag gctgcggcag tcgtccggca cgaccccggc ggcgtcgaac ttcttgcggt
    13801 acagctccac gttgtcgtac gcgtgccgca gggtcgcccg cagccggtcg agctggagct
    13861 cctggagctg ctcggaggag aggcgctcgg cgtcgtcgag caggtcgtgg gggaggggct
    13921 cgccccgtcg ggttgccggg gcggccccgg tcgtcggctc gctgctcatc gcgactcctt
    13981 cgtcgtcgtg cccggcgtcc cgcgcgccgc gccctcccgc gcgcggtggg tgatctcgtc
    14041 ccgccgcgcg tcgtggccgt cctcgtcgtc gcgcgcgtgg tggccgtttc cgtcgtcccg
    14101 ggcgcgggga ccgacgccgt cgccccgcgc gctgcggctg cggccgcgga actccgcgat
    14161 cacctcgtcg ccgcgccgca cgctcacgtc gtagatccca ctgcgcccgt agcgggcacg
    14221 ctcctcggcg cgggccacga gcacgtcgcc ctcgcgggcc ggggcgacga agacgatgtc
    14281 ggcgccggcc gcgacggtca cggggccgtg gctgttgcac gcgcaggcga acgcggtgtc
    14341 ggccagcagg aacaggaagc cgccgtgggc aatccggtgg ccgttgacca tcgccggggt
    14401 cacggtcatc cggaccaccg cggatcccgc gccctgctcc accagctcga tgcccagccc
    14461 gcgggaagcc cggtccgcgg cgaacatcac ctccgcgggc gtctgctcgg cggcctgcga
    14521 cacctctccc accaccctgt atcccggccg gtaccccgac cgaccattcg gtcagcttgc
    14581 ggcacggccc agtaatccag ccggccgctc gccctgtcaa gggtgcgggc ggcggggttc
    14641 cggggtcttg cccggcgacc ggaaacccgt cacactgata ccgaacgaat ggtcggttgg
    14701 gaagctggtg acgatgacca cgacacacgc cgccgaggca ccgcccccgc aggagccgga
    14761 cggactccag gagcacttcg acgcgaccgt cgcgcgcgac cagcgcgtcg aaccgcgcga
    14821 ctggatgccg gacggctacc ggaagacgct gatccggcag atcgcccagc acgcgcactc
    14881 ggagatcatc ggcatgcagc ccgagggcga gtggatcacg cgggccccgt cgctgcgccg
    14941 caaggcgatc ctgttcgcca aggtccagga cgaggccggc cacgggctct atctgtactc
    15001 ggcggccgag accctcggcg cggaccgcga cgacctcacc gagcggctga tcgagggtcg
    15061 ccagaagtac tcgtcgatct tcaactaccc gaccctgagc ttcgccgacg tcggcgtgat
    15121 cggctggttc gtggacggcg ccgcgatctg caaccaggtg ccgctgtgcc gcagttccta
    15181 cgggccgtac gcgcgcgcga tggtgcgcat ctgcaaggag gagtccttcc accagcggca
    15241 gggctacgag ctgctgatga cgatgatgcg cggcaccccg gcgcagcgcg agatggtcca
    15301 ggacgccgtg gaccgctggt ggtggccctc actgatgatg ttcggcccgc ccgacgacgc
    15361 ctcacccaac tcggcgcggt cgatggcctg gaagatcaag cggcacagca acgacgaact
    15421 gcgccggcgc ttcgtcgaca tgacggtccc gcaggccgag aagctcggcg tcaccctgcc
    15481 cgaccccgag ctgcgctgga acgaggaggc ggggcaccac gacttcggca cccccgactg
    15541 ggacgagctg acgcgcgtca tcaagggcga cgggccgtgc aacgcccagc gcacggagcg
    15601 acggcgcacc gcgcacgagg agggcgcctg ggtgcgcgag gcggccaccg cccacgccgc
    15661 caagcaggcg gcccgcacgc agaagggagc ggcggtatga gcgccgaccg gcccgagcgg
    15721 cagggctggc cgctgtacga ggtgttcgtg cgcggcaagc gcggcctcaa ccacgtccac
    15781 gtcggctcgc tgcgcgccgc cgacgacgcc atggccctca cccacgcccg cgacctctac
    15841 acccggcgca acgagggcgt gagcatctgg gtggtgcgct ccgagcacat cgccgcctcc
    15901 acccgcgacg agaaggaccc cttcttcgcc cccagcgccg acaaggtcta ccggcacccg
    15961 accttctacg acatccccga cgacgtcccc cacatctagg agcagggcat gagcgacgac
    16021 cacgtctacc tcaccctggc cgagggacac gaggacgaca cccgctgggc ctacggcacc
    16081 ggtttcgagg acccgctgca cggcgtcgac accaccgtgc ccgagggcgt cgacgccgcc
    16141 ggactggccg cggagtgcgt ggcgctggcc gacgacgccc tcgtcggtgc ccagcggctc
    16201 gccgagtgga tcacccgtgc gcccgagctt gaggaggagg tggcgctggc caacatcggc
    16261 ctcgacctcc tcggccaggc ccgcctgctc tacacccgcg ccgggcaggc cgacggcacc
    16321 ggccgcgacg aggacgccta cgcctacttc cgcgacgccg ccgacttccg caacgtgacg
    16381 ctggcggaac tgcccggcgg cgacttcgcg ttcaccgtcg tacggctgct ggtgctctcc
    16441 agctggcgcc tggcgcactt ccgggggctg gtggaccacc cggacccggt cctcgcggcg
    16501 gtcgccgcca agggcgtcaa ggagctgacc taccaccggc agtacgccgc ccagtggtgc
    16561 gtacgcctgg gcgacggcac ggacgagtcg caccgccgga tgcgggtggc gctggagcag
    16621 gtcgccccct acctcggcga actgcacacg gcccacgacg tgcgggacga ggtcgccgcc
    16681 gacctgcgcc aggtcaccga cgccgccgga ctgcccctgc cggtctaccg cccgctgccc
    16741 ggctccggcc gcgcgggcga gcacaccgag catctggcgc cgctgctcac cgagttgcag
    16801 ggcatcgccc gcgcccaccc ggaggcgaca tggtgaccgc cggccccgcc ctcccggacg
    16861 cccaccgcgc ccggcgcgtc gccgagcgcg tgccggaccc cgagctgccc atgctgaccc
    16921 tcgccgacct gggcgtcctg cgcgacgtcg agacgcgggc ggacggcacc gtggtcgcga
    16981 gcctgacccc cacctactcg gggtgtccgg ccatggcgga gatgcgcgcg gacgtcgccg
    17041 cacggctgcg cgcggcgggg tacgcgcgcg tggagatccg caccgtcctg gacccgccct
    17101 ggaccagcga ctggatcacg gagtccggcc gccgcaagct cgccgagcac ggcatcgccc
    17161 cgcccggccg cgctccccgc ggcccggtcc cgctgctgct gtcgcccacc cggcccgcgg
    17221 tgccctgccc ccgctgcggg tcgcgggaga ccgaggagac ctcgcgcttc gccgccacct
    17281 cctgcaaggc actgtggcgc tgccgggcct gccgcgagcc gttcgagtac gtcaaggaga
    17341 tctgatggcc ccgaccgccc ccgtaccggc ggcccccgca cgcgcccgcc gccgccccgc
    17401 cttccaccgc ctgcgcgtcg cggccgtgga gcggctgtgc gcggacgcgg tggccgtgcg
    17461 cttcgaggtc ccggacgagc tcgccggggc gtatgccttc gcgcccggac agtcgctcac
    17521 cctgcggcgc gaggtcgacg gccgggacga gcgccgttcc tactcgatct gcgtggcggc
    17581 cggttcggct ccccgcatcg gggtgcgggt ggtgccgggc ggcctgttct ccgcctggct
    17641 ggtggacgag gtgcgcccgg gcgacaccgt cgaggtgatg acgcccaccg gcctcttcac
    17701 gcccgacctg accgtcccgg gccaccacgt gctgatcgcg gccggttcgg gcatcacgcc
    17761 gatggtgtcc atcgccgagt cggtgctcgc cgccgacgac cgctccaccg tcaccctctt
    17821 ctacggcaac cgccgcaccg gcacggtgat gttcgccgac gaactggccg acctgaagga
    17881 cctccacccg gcccgcttcc agctcgccca cgtcctctcc cgcgaaccgc gggaggccga
    17941 gctgctctcc ggccgcctgg acgccgagcg gctgaccgcg ctggtcggct ccctggtgga
    18001 cgtggaggcc gccggccact ggtggctgtg cgggccgcag ggcatggtcg ccgacgccca
    18061 gcaggtcctg gccggcctcg gcgtgcccgc ggaccgcgtc caccgcgagc tgttcttcgc
    18121 cggcgacgag cccgtgcgcg aggtccacca cgaggagggt ggcccccggg ggccggtcag
    18181 cgaggtcacc gtcaccctgg acggccgctc caccaccgcc tccctctccc gggaacggag
    18241 catcctcgac ggtgcccagc agacccggcc cgacctcccc ttcgcctgca agggcggcgt
    18301 gtgcggcacc tgccgcgccc tggtcaccga cggcaaggcc gacatgcgcc gcaactacgc
    18361 cctggaggcg gccgaggtcg acgccggtta cgtgctgacc tgccagtcct acccggtctc
    18421 cgagcagctg accgtggact acgacagctg aggccgcgcg cgaccggccc acggcagcgc
    18481 ggacgactac cgagcgcacg accgcggaga cgacgaccgc ccagtggcac gactgccgag
    18541 cgtacgaccg cggagaggac gaccgcccag tggcacgact gccgggcgca cgcccgtccc
    18601 ggccggccgc cgccgggacg ggcgaacact atgaacgcaa tgatccaaag gctggccccg
    18661 gctccggacg gttcctaaca tcccggctcg cagcgcaaaa tcgcgcccgc acgcagcacg
    18721 tacaggagcc gcaccttgac cacacccgac gctcccacgc atgccaccgg ggccatgcac
    18781 cgcagaagcc gccccgcggt ggtggccgcc gcgctggcgg ccgtgttcct cggcaccctc
    18841 ggcaacgtct ccgccgcccc cgcccgggcg gccgtggagc ccacggccgg gcagccggtg
    18901 gccgccgact gtccgcccgc cctcgccgag aaggccacct gctacaccgg gcaggacgag
    18961 aacggggcct actacacgat ggccgtgccc caccgctgga acggctccct cgtcgtgcac
    19021 gcccacggcg gccccgacct cggcgacacc tccgaccccg cccgcagcac cgaggacctg
    19081 ggacgctggg cggtgatggt cgacgagggg tacgcctggg cgggttcctc ctaccggcgc
    19141 ggcggttacg gggcccgcat ggcggccgcc gacaccgaga acgtgcggcg cctgttcacc
    19201 gaccggttcg gccgcccgga gcgcacctac ctgcacggcc agtcctgggg cggcaacgtc
    19261 gcggccaagg tcgccgagac gtacggcggg cgccccggcg cctacgacgg ggtgctgctg
    19321 accaacggcg tactcggcgg cggttcgcgc ggctacgact accgcgtcga cctgcgggtg
    19381 gtctaccagt actactgcca caaccacccg cgcccgaccg agccgcagta ccccctgtgg
    19441 caggggctgc gggccggctc cacgatgacg accgccgggc tgcgcgcccg cctccaggag
    19501 tgcacgggct acgcctcgga cccggccgac cggaccgggc cgcagcagcg caacctcgac
    19561 gacatcctcg ccgtcacggg cattcccgag cgcaccctgg agtcgcatct gcggttcgcc
    19621 accttcacgt tccgggacat cgtggccaac cggctcgacg ggcggaaccc gtggagcaac
    19681 cggggagtgc gctacaccgg ctcgcacgac gacaaggcgc tcaacgcggg cgtcgaacgc
    19741 ttctcggccg accccaccgc gcgccgtgac ctgtcctacg acagcgacct caccggcagg
    19801 gtgtccctcc ccgtcctcac gatgcacgcc atcgacgacc cgacggcctt cgtggagcac
    19861 gaggcggcct accgcgccac cctgcggggc gcgggacgtg gcgggaacct cgtccagacg
    19921 ttcacgaagg agcacgagca cagctcgctg agcgactccg agtacgccaa ctccatggcc
    19981 gcgctggaca cctgggtcag caccggccgg cggccgagcc cgcgtgcgat cgcggcctcc
    20041 tgcgccgact tcgacgcgac gtacggcgac ggctgcttct acgaccccgg tttccgcccc
    20101 gcgccgtacg cctcgcgggt gctgccccgg ccgggcggcc tcacctggcc cgccatgacc
    20161 gccgcgcggg agcgggcgtg gagcagcatc cagggcgtgg ggatcgctcc ctagccggtc
    20221 cggtccgccc ggtccgcccg gcacgtcgag cgcgccgggc ggacctagtg gtgtgtcaga
    20281 cgccgaactc cgcgggcgag atgcccaggg cggagcaggc ctcgcggatc gcctgctgct
    20341 cggagggctc gaagaccccg tcggccccgg cgacgaccat gccggtctgg atgacggcac
    20401 gagcctcctc gggcttcttc gacgccttgg cgatcacctg cagggcctcg ctcctgccct
    20461 gctcgacgtt ggcgaggagc cggtccacgt gctggttgaa ccgctgacgg agctggtccg
    20521 cggggaagtt ctgcagcacc tcgttggaga cgatcagctc ctccacgcgc gtgcgctccg
    20581 ccggttccac gtgcccgtcg gccgcggcga ccagcgcgca catggccatg ctggcgtccc
    20641 ggtaggagcc gctcttcaac tcggtcttga ccgacgcgag ctgggacttg aacatcccga
    20701 tcagctgcgt cttggagcct ccggacgaac ccggccggcc gctcgcctgc gcgccctggc
    20761 cggatccgct cgctccccga gtgccctggg actgctggaa ggtcttggcc tggtccttga
    20821 tcttgtccca catcgccact cgtgccacct cggcttctgt tgttgtgcgt ctggctgttg
    20881 tgcgtccggc cgtcgtgcgt tccggcccgg tcccaacccg cggtctcccg cggggattcc
    20941 gcagccacca ggatgaacgg gccgtggcac cacagggttc cctaaaggca aagaaaaggc
    21001 aaagaggctg atgggggcgg agtaggctgc cccgacagaa gccgccgaac cggcggccgg
    21061 gcgggagcgt acggtgtggt cgcggcaggt cggctggttc gtcgcgatcg gcgtcgtgtc
    21121 gaccgcgggt caggcgc
//
