LOCUS       NZ_CP043317            11335 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Streptomyces olivaceus strain SCSIO T05 chromosome, complete genome.
ACCESSION   NZ_CP043317
VERSION     NZ_CP043317.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces olivaceus
  ORGANISM  Streptomyces olivaceus
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8458055)
  AUTHORS   Zhang,C., Ding,W., Qin,X. and Ju,J.
  TITLE     Genome Sequencing of Streptomyces olivaceus SCSIO T05 and Activated
            Production of Lobophorin CR4 via Metabolic Engineering and Genome
            Mining
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8458055)
  AUTHORS   Zhang,C., Ding,W., Qin,X. and Ju,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2019) Key Laboratory of Tropical Marine
            Bio-resources and Ecology, South China Sea Institute of Oceanology,
            Chinese Academy of Science, NO.164 Xingang Road, Guangzhou,
            Guangdong 510301, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 28-MAR-2017
            Assembly Method                   :: HGAP v. MAR-2017
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 8458055.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015244315.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 18:39:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,352
            CDSs (total)                      :: 7,265
            Genes (coding)                    :: 7,077
            CDSs (with protein)               :: 7,077
            Genes (RNA)                       :: 87
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 188
            CDSs (without protein)            :: 188
            Pseudo Genes (ambiguous residues) :: 0 of 188
            Pseudo Genes (frameshifted)       :: 106 of 188
            Pseudo Genes (incomplete)         :: 98 of 188
            Pseudo Genes (internal stop)      :: 7 of 188
            Pseudo Genes (multiple problems)  :: 23 of 188
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:52:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2090688
            Orig. end                         :: 2102023
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP043317.1.
            Bacteria and source DNA available from South China Sea Institute of
            Oceanology, Chinese Academy of Science; 164 West Xingang Road,
            Guangzhou 510301, China.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..11335
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="17"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..11335
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..11335
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:6335](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..6335
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            193..1176
                     /db_xref="GeneID:69760150"
                     /locus_tag="FYC74_RS08750"
     CDS             193..1176
                     /NRPS_PKS="Domain: PKS_ER (19-324). E-value: 3.5e-50.
                     Score: 162.8. Matches aSDomain:
                     nrpspksdomains_FYC74_RS08750_PKS_ER.1"
                     /codon_start=1
                     /db_xref="GeneID:69760150"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009192933.1"
                     /locus_tag="FYC74_RS08750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_194275479.1"
                     /sec_met_domain="ADH_N (E-value: 9.8e-08, bitscore: 30.6,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.1e-17, bitscore:
                     63.0, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRVVVFDEFGGPEVMHVVEEPVVEPAAGEVRVRIEAFAVNPLDR
                     MMRSGTSPATVPLPHARLGVEGTGVVDALGPGATGLEAGDPVVLAAVPDASARGSYAEY
                     TTVPASQVVARPAGLGVTEAAAVWVGYSTAYGALVEKAGMRPGDHVLITAASGGVGRAA
                     LQIARQIGAVPLAVTRHTANRDDLLAAGAAAVVATDRTDVVEAVRHHTGGAGVDIVLDL
                     VMGPGQQDLLRAARPGGTLVAAGFLDPRPTPFPTGTPLRVFSYRSFEHTLDAVVVRRMA
                     AFLNAGVRLGALRPAVGEVFALDDIVEAHRHLERGLHAGKKIVVTV"
     aSDomain        250..1164
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FYC74_RS08750_PKS_ER.1"
                     /evalue="3.50E-50"
                     /label="FYC74_RS08750_PKS_ER.1"
                     /locus_tag="FYC74_RS08750"
                     /protein_end="324"
                     /protein_start="19"
                     /score="162.8"
                     /tool="antismash"
                     /translation="EEPVVEPAAGEVRVRIEAFAVNPLDRMMRSGTSPATVPLPHARLG
                     VEGTGVVDALGPGATGLEAGDPVVLAAVPDASARGSYAEYTTVPASQVVARPAGLGVTE
                     AAAVWVGYSTAYGALVEKAGMRPGDHVLITAASGGVGRAALQIARQIGAVPLAVTRHTA
                     NRDDLLAAGAAAVVATDRTDVVEAVRHHTGGAGVDIVLDLVMGPGQQDLLRAARPGGTL
                     VAAGFLDPRPTPFPTGTPLRVFSYRSFEHTLDAVVVRRMAAFLNAGVRLGALRPAVGEV
                     FALDDIVEAHRHLERGLHAGKKIV"
     CDS_motif       631..693
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FYC74_RS08750_0001"
                     /evalue="2.10E-07"
                     /label="PKSI-ER_m5"
                     /locus_tag="FYC74_RS08750"
                     /protein_end="167"
                     /protein_start="146"
                     /score="23.4"
                     /tool="antismash"
                     /translation="GDHVLITAASGGVGRAALQIA"
     gene            complement(1205..1534)
                     /db_xref="GeneID:69760151"
                     /locus_tag="FYC74_RS08755"
     CDS             complement(1205..1534)
                     /codon_start=1
                     /db_xref="GeneID:69760151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018554548.1"
                     /locus_tag="FYC74_RS08755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_194275480.1"
                     /transl_table=11
                     /translation="MSDTSNYYGDVVNVHGGERVIGIYHNTAPDTELRAAVADLTRLLG
                     ELRPELSPDQARTVDDALPALTPDRAALRERGMILASVSQIAATVGEVGRPVMEALGRL
                     LALLG"
     gene            complement(1531..1806)
                     /db_xref="GeneID:69765674"
                     /locus_tag="FYC74_RS36615"
     CDS             complement(1531..1806)
                     /codon_start=1
                     /db_xref="GeneID:69765674"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FYC74_RS36615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_228123318.1"
                     /transl_table=11
                     /translation="MVLVGFALVVVCAVLLSSRKPVLIFELNSGSRVVLTLPTMDELRA
                     IAGQIVYAIDHPEYEFTAVLEQHNTTNNFGSVVNLNGGRGNTGMKL"
     gene            complement(2548..3222)
                     /db_xref="GeneID:69760152"
                     /locus_tag="FYC74_RS08765"
     CDS             complement(2548..3222)
                     /codon_start=1
                     /db_xref="GeneID:69760152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972873.1"
                     /locus_tag="FYC74_RS08765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter"
                     /protein_id="WP_194275481.1"
                     /transl_table=11
                     /translation="MTALLRYQAALLLRSRRWLPPVVLYAAALGIGVQGGQPVLDSLGW
                     SAAVLLPVAAWLVRISVTGEPSAARGCVAAARGPGRAHLASVLVALAAAVVLGAAATFV
                     VALISAPVSTGHGTRVALLPAAGAGLLAALVCALLGTAVGALTTWPVLRSPGRAVPALL
                     LAALLALVASGSPARAAVSGLVTGSRSGAVPLPLLPLAAAAALASAATAAACALSSRRP
                     AA"
     gene            complement(3219..4073)
                     /db_xref="GeneID:69760153"
                     /locus_tag="FYC74_RS08770"
     CDS             complement(3219..4073)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69760153"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972874.1"
                     /locus_tag="FYC74_RS08770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_194275482.1"
                     /transl_table=11
                     /translation="MRPELRLNGVGRRYGVRGPWVLRGVELDVAPGTLVRVEGTNGTGK
                     STLLRLLAGIDAPTEGRVTGRPRTAYVPERFPPALPFTALQYLTHLGTVHGLPRRSAAR
                     AAGEWLERLGAGEYAGTPLARLSKGSSQKVAVAQALLAEPELLVLDEAWTGLAAEARGE
                     LERAVAERTAAGGAVVFVDHDPRRLADAPDAVYAVRDGALHRRTAPAGVPDGPRVVVRV
                     RGPSDAALPADVRRTVVRAEETGPGCHTLAVPASHSDVLLRTLLTARPPWHVVSVHAPE
                     DRR"
     gene            4141..4875
                     /db_xref="GeneID:69760154"
                     /locus_tag="FYC74_RS08775"
     CDS             4141..4875
                     /GO_function="GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69760154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030616.1"
                     /locus_tag="FYC74_RS08775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptidyl-tRNA hydrolase"
                     /protein_id="WP_194275483.1"
                     /transl_table=11
                     /translation="MPVPATDPASVPAPDSPFRAEAGDRDLAPQFVLPLVVRIERAAPP
                     HRTDALETAARAVLVMLGDERSTGDGEWARAVRDWQDARIRKVVRRARGAEWRRAEALP
                     GITVGGKTAEVRVFPPVPLDGWPKDLARLQVSGTDLDDPEPPAGADPAAPVLWMNPDLD
                     MSAGKAMAQAGHGAQLAWWELSDGERAAWRDAGFPLSVRTADPSRWSGLTTGGLPVVRD
                     AGFTEIAPGSCTVVADHPALRR"
     gene            5001..6335
                     /db_xref="GeneID:69760155"
                     /locus_tag="FYC74_RS08780"
     CDS             5001..6335
                     /codon_start=1
                     /db_xref="GeneID:69760155"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016327585.1"
                     /locus_tag="FYC74_RS08780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_194279404.1"
                     /sec_met_domain="DUF692 (E-value: 1.7e-95, bitscore: 318.0,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMRLGTGIGWRPEIADVVERMPGIDWVEAVSENLCPGHLPDSLLR
                     LRRRGVTVVPHGVSLGLGGAERPDAGRLAALAERAGVLGAPLVTEHIAFVRAGGAPAAS
                     PLLEAGHLLPVPRTRDALDVLCENVRIAQDALPVPLAVENIAALFSWPDEELTEGQFLY
                     ELADRTGVRLLIDVANLHTNHVNRGEDPAEALGELPLEAIAYVHVAGGFERDGVWHDSH
                     AHPVPRPVLDILTDLASRVAPPGVLLERDENFPEGEELAGEVASIRAALAEGRAGGAPG
                     GPDPAGPHRAVPRGAGDVAGAGDAVRQRLGRAQHALLASLVAGAPVPEGFDRARLGVQA
                     RALAGKRADVVAKVAPELPVILGPRYRPAFLAYARTRPMTGGYRRDALDFAEHVLRAGA
                     GPEETFRDVRRELREWWRERSGPVPRSARPGARLARATRRVLLRR"
     misc_feature    6435..6451
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.13"
                     /tool="antismash"
     gene            6453..7259
                     /db_xref="GeneID:69760156"
                     /locus_tag="FYC74_RS08785"
     CDS             6453..7259
                     /codon_start=1
                     /db_xref="GeneID:69760156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019073953.1"
                     /locus_tag="FYC74_RS08785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TIGR04222 domain-containing membrane protein"
                     /protein_id="WP_194275484.1"
                     /transl_table=11
                     /translation="MFWVLFLLSAWAVAGLACLRLCLAAVRAAAAAAAAPRSVAREHAL
                     TLYEAAFLSGGPRRVADLTLVSMARQRRLLLAHTGWATVVDPCGRDDMERSVIGAIGPE
                     GQSRIAPVRAAAATADAVRGLADRLVGAGLAVPDGGAGGVADGVRRVRAAAATVCALGL
                     AALALPLPATEPRLLVALWFTLPLALTLGCLVITRMEVHPYSRWASPAGQRLIGALVQR
                     ADGTADDRTFLTSVAVRGVHAIGEPDLRAAFAHREEYAEEHRERRV"
     gene            7384..8979
                     /db_xref="GeneID:69760157"
                     /locus_tag="FYC74_RS08790"
     CDS             7384..8979
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (110-485). E-value:
                     3.4e-20. Score: 64.6. Matches aSDomain:
                     nrpspksdomains_FYC74_RS08790_Abhydrolase_1.1"
                     /codon_start=1
                     /db_xref="GeneID:69760157"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125237.1"
                     /locus_tag="FYC74_RS08790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_194275485.1"
                     /sec_met_domain="PF00561 (E-value: 1e-23, bitscore: 83.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAAALYSAAGSLLLTTLTAGPARAATPAGPESPEARGTAVAAGR
                     AAAAGITFGSCPKAEELPGGIRCGTVSVPLDYAHPDGKQIELAVSRVPATHKDPDNGKH
                     KVPGQGALLYNPGGPGASGLYFPLVGMVPEWKRIAAAYDLVGYAPRGVAPSAPLSCQDP
                     GDFFKGPRPAPTQPSDAYKAERAAEAETYAHDCAARAGDALRHYHSLNNARDLEVVRAA
                     LGERRLTFMGASYGTYLGALYAELFPSHVRRMVFDAVVNPDPEQVWYRNNLDQSEAFED
                     RWDDFKEWVAEHDAEYGLGDTPRKVQDGYDEASARLAKEPAGGTVGPAQLQGAMLKAGY
                     YDDYWPHRAEALSAYLKGDPQPLVDQAGTRTEEGSVAAENSNAVYTAVECNDAPWPTDF
                     RVWDRDNTRLARRAPFETWDNVWANLPCAYWRAPRQQPLDVRTAPGELPPTLVLAAERD
                     AATPYEGALELRRRLSGSVLVTERDAGTHGIAAGPNACVNDHLEAYLLEGRLPARDTSC
                     APRPEPRPQPQPRT"
     aSDomain        7714..8838
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FYC74_RS08790_Abhydrolase_1.1"
                     /evalue="3.40E-20"
                     /label="FYC74_RS08790_Abhydrolase_1.1"
                     /locus_tag="FYC74_RS08790"
                     /protein_end="485"
                     /protein_start="110"
                     /score="64.6"
                     /tool="antismash"
                     /translation="ALLYNPGGPGASGLYFPLVGMVPEWKRIAAAYDLVGYAPRGVAPS
                     APLSCQDPGDFFKGPRPAPTQPSDAYKAERAAEAETYAHDCAARAGDALRHYHSLNNAR
                     DLEVVRAALGERRLTFMGASYGTYLGALYAELFPSHVRRMVFDAVVNPDPEQVWYRNNL
                     DQSEAFEDRWDDFKEWVAEHDAEYGLGDTPRKVQDGYDEASARLAKEPAGGTVGPAQLQ
                     GAMLKAGYYDDYWPHRAEALSAYLKGDPQPLVDQAGTRTEEGSVAAENSNAVYTAVECN
                     DAPWPTDFRVWDRDNTRLARRAPFETWDNVWANLPCAYWRAPRQQPLDVRTAPGELPPT
                     LVLAAERDAATPYEGALELRRRLSGSVLVTERDAG"
     gene            complement(9089..9820)
                     /db_xref="GeneID:69760158"
                     /gene="hemQ"
                     /locus_tag="FYC74_RS08795"
     CDS             complement(9089..9820)
                     /EC_number="1.3.98.5"
                     /codon_start=1
                     /db_xref="GeneID:69760158"
                     /gene="hemQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018564417.1"
                     /locus_tag="FYC74_RS08795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hydrogen peroxide-dependent heme synthase"
                     /protein_id="WP_194275486.1"
                     /transl_table=11
                     /translation="MSDDASTPAAERTPNKGKLAKDLNEVIRYTLWSVFKLKDTLPEDR
                     AGYADEVQELFGRLAAKDVTIRGTYDLSGLRADADLMIWWHAETADQLQEAYNLFRRTK
                     LGRALEPVWSNMALHRPAEFNRSHIPAFLADETPRNYISVYPFVRSYDWYLLPDEDRRR
                     MLADHGKMARGFPDVRANTVASFSLGDYEWILAFEADELHRIVDLMRHLRGSEARRHVR
                     EEIPFYTGRRKDIGELVAGLA"
     gene            complement(9825..11312)
                     /db_xref="GeneID:69760159"
                     /gene="hemG"
                     /locus_tag="FYC74_RS08800"
     CDS             complement(9825..11312)
                     /EC_number="1.3.3.4"
                     /GO_function="GO:0004729 - oxygen-dependent
                     protoporphyrinogen oxidase activity [Evidence IEA]"
                     /GO_process="GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69760159"
                     /gene="hemG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007445289.1"
                     /locus_tag="FYC74_RS08800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="protoporphyrinogen oxidase"
                     /protein_id="WP_194275487.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 4.4e-07, bitscore:
                     28.2, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 9.5e-09, bitscore: 34.0,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCASENPSEDPAGERPADPDHVVVVGAGIAGLAAAHRLLEHGVRV
                     TVVEASDRVGGKLLPGEIAGVRVDLGAESMLARRPEAVGLARAAGLADRLQPPSTATAS
                     LWTRGALRPMPKGHVMGVPGTAAALSGVLSEEGLARIERDAELPRTEVGEDVAVGEYVA
                     ARLGREVVDRLVEPLLGGVYAGDAYRISLRSAVPQLFEAARTHTSLTEAVRALQGRTAT
                     SPPSGPVFTGIEGGVGTLPLAVAESVRARGGEIVTGAPVTELRHTAGGWRVVAGDRVLH
                     AAAVVVAVPARPAAELLRAEAPAAAAELSAVEYASMALITLAYRRSDAAALPEGSGFLV
                     PPVDGHTIKASTFASRKWGWIADEGPDLVVLRTSVGRYGDTEILGRDDAGLVAVSRHDL
                     REATGLAAAPVATRVTRWQDGLPQYPVGHHARVARVREHVAGLPGLAVCGAAYDGVGIP
                     ASIASAYAAVDQVRGDLRGVEELTAHPVQSLHGGAGE"
ORIGIN
        1 actgagcccg aagagcacga gcacggccca cttgtcggag atgatctcga ccgccaggcg
       61 cgtggggcag tcggcgagga aggctggtcc agccacgttc cgcatgacat tcgaaggtac
      121 caggaggtac ccgacggctc cgtagcgtct tccgtgagca acgaaaccag cagcggacgc
      181 agaggagtca ccatgccacg agtcgtcgtg ttcgacgagt tcggcgggcc ggaggtcatg
      241 cacgtcgtcg aggagccggt cgtcgagccc gccgccggcg aggtacgggt caggatcgag
      301 gcgttcgccg tcaacccgct cgaccggatg atgcgttcgg gcacctcgcc cgcgaccgtc
      361 cccctgccgc acgcccgcct cggcgtcgag ggaaccggcg tcgtcgacgc gctgggcccc
      421 ggagccaccg ggctggaggc cggcgatccg gtcgtcctcg cggccgttcc ggacgcgagc
      481 gcccggggca gctacgccga gtacaccacg gtccccgcga gccaggtcgt cgcccggccg
      541 gccgggctcg gagtcacgga ggcggcggcg gtctgggtcg ggtactccac cgcctacggc
      601 gcgctcgtcg agaaggcggg gatgcggccc ggcgaccatg tcctcatcac cgccgcgtcc
      661 ggcggcgtcg gccgcgcggc cctccagatc gcccgacaga tcggcgccgt gcccctcgcc
      721 gtcacccggc acaccgcgaa ccgggacgac ctgctcgccg cgggcgccgc cgcggtcgtc
      781 gccaccgacc gcacggacgt cgtcgaagcc gtccgccacc acaccggcgg ggccggcgtc
      841 gacatcgtcc tcgacctcgt catgggcccc ggccagcagg atctcctgag ggcggcccgc
      901 cccggcggaa cactggtcgc cgcgggcttc ctggaccccc ggcccacgcc cttcccgacc
      961 ggcacgccgc tcagggtctt cagctaccgg agcttcgagc acaccctcga cgccgtcgtg
     1021 gtgagacgca tggcggcctt cctgaacgcc ggcgtacgcc tcggtgcgct gcggcccgcc
     1081 gtcggcgagg tgttcgccct cgacgacatc gtcgaggcac accgccacct ggaaaggggg
     1141 ctgcacgccg ggaagaagat cgtcgtcacg gtctaagaac ggagggagcg cgcgatgagg
     1201 cccgtcagcc cagcagcgcg agcagccggc ccagcgcctc catgacgggc ctgcccacct
     1261 cgcccacggt cgccgcgatc tgcgagacgg acgccaggat catgccgcgc tcacgcaggg
     1321 cggcccggtc gggggtgagc gcgggcagcg cgtcgtccac ggtccgggcc tggtccgggg
     1381 acagctccgg gcgcagctcg ccgaggaggc gggtgaggtc cgccacggcg gctcgaagct
     1441 cggtgtccgg agcggtgttg tggtagatgc cgatgaccct ttcgccgccg tgcacgttga
     1501 cgacgtctcc gtagtagttc gacgtgtcgc tcacagtttc atccccgtgt tccccctgcc
     1561 gccgttcaag ttgacgacgg aaccgaagtt gttcgtggtg ttgtgctgct cgaggacggc
     1621 ggtgaactcg tactccgggt ggtcgatcgc gtacacgatc tgcccggcga tcgcccgcag
     1681 ttcatccatg gtcggcaggg tgaggaccac cctggaaccg ctgttcagct cgaagatcag
     1741 caccggcttc cgcgacgaga gcaggacggc gcagacgacg accagggcga acccgaccag
     1801 gaccaccagg gtggggccgc cccctcgtcc agggagccga gctggtcgga gaacaacgag
     1861 gcgctgacca ccaccagcag gaggtagagg ccggccttgc cccagtcggg cctcagcctg
     1921 aacacttcga cccagctgac gttgggcagc ggaaccgccg ccgacccgac ccacaggatg
     1981 tgcctaagga cctggagttg cagcggcttt cccttgcgcg gaggcagcgg cacaggcggt
     2041 atcccggagg gcgcctgcgg cggcggggac gaaggccggg gcggaatccc cggcaagggc
     2101 ccggaaggtc tcccgggagg tggtacgcca atgccgcccg tgtgatccat ggttcccccg
     2161 taccttcgtc acgactgccc gcgcagcgcg tggcgcggga gcctcattaa gcctctgcgg
     2221 ggtcgaggga cggcaggcga gatacggcca atctgccttc gattcccagg gatgagccag
     2281 aggttggtcg tcgtgtgcgg gggctgcgga ccgccgggac actccggcct accctggagg
     2341 gatgagcggc gattccgacc gggccccgga cgactcctcc ccttcgacgc cgcccggccg
     2401 ccggaggccg agggccctcc gtacgcggac tgcgtcctgt gccgggagcc gacggagtat
     2461 ccggagtcgt acaagggcat cacgctctgc ccggtctgcg catggcagga ggcccaacgc
     2521 acggcctgct cgggctgacc ggcccgctca ggccgctggt cggcgcgagc tgagcgcaca
     2581 ggcggcggcg gtcgcggccg aggcgagtgc cgcggcggcg gccagcggca gcagcggcag
     2641 ggggaccgcg cccgacctcg acccggtgac caggccgctg accgccgccc gcgccgggga
     2701 gcccgacgcc accagcgcca gcagggccgc cagcagcagg gcggggaccg cgcggccggg
     2761 cgagcgcagc accggccagg tggtgagcgc gccgacggcg gtgccgagca gggcgcacac
     2821 cagcgcggcg agcagcccgg cgcccgccgc cgggagcagg gccacgcgtg tgccgtgtcc
     2881 ggtgctgacg ggggcgctga tcagcgccac gacgaaggtc gccgccgcgc ccaggacgac
     2941 cgcggcggcc agcgccacca gcacggacgc caggtgggcc cgcccgggac cgcgtgccgc
     3001 cgccacacag ccccgggcgg cggacggctc acccgtgacg gagatccgca ccagccaggc
     3061 cgcgaccggc agcagcacgg ccgccgacca gcccagcgag tcgagcaccg gctgcccgcc
     3121 ctgcacgccg atgccgaggg cggcggcgta caggacgacg ggcggcagcc agcgccggga
     3181 gcgcagcagc agggccgcct ggtagcgcag gagagcggtc atcgtcggtc ctccggggcg
     3241 tgcacgctca ccacgtgcca gggcggccgg gcggtcagca gcgtgcgcag cagcacgtcg
     3301 gagtgggagg cggggacggc gagcgtgtgg caaccggggc cggtctcctc ggcccggacg
     3361 acggtccggc gtacgtcggc gggcagggct gcatcggacg gaccccgcac ccggacgacg
     3421 acacgcggcc cgtccgggac gccggccggg gcggtacgac ggtgcagggc gccgtcgcgg
     3481 accgcgtaca cggcgtcggg cgcgtcggcc aggcggcgcg gatcgtggtc gacgaagacg
     3541 acagccccgc ccgccgccgt ccgctcggcg accgcccgtt ccagctctcc gcgtgcctcc
     3601 gcggcgagcc cggtccaggc ctcgtcgagg acgagcagct ccggctcggc gagcagggcc
     3661 tgcgccaccg ccaccttctg gctgctgccc ttggacagcc gggcgagcgg tgtgcccgcg
     3721 tactccccgg ccccgagccg ctccagccac tcccccgccg cacgcgccgc cgaccggcgg
     3781 ggcagcccgt ggacggtgcc gaggtgggtg aggtactgga gggcggtgaa gggcagggcg
     3841 ggcggaaagc gttcggggac gtaggcggtg cgcggccggc cggtgacccg gccctcggtg
     3901 ggggcgtcga tcccggcgag caggcgcagc agggtcgact tgccggtgcc gttggtgccc
     3961 tcgacgcgga ccagggtgcc gggcgccacg tccagttcga cgccgcgcag cacccagggg
     4021 ccgcggacgc cgtagcggcg ccccacgccg ttcagccgta gctcgggtcg catggggcca
     4081 tcctctcgcg gggctcgggc ggacggttgg cagactgtcc gggtgagcaa tgatccggcg
     4141 atgcccgttc ccgctaccga ccccgcctcc gtccccgccc ccgacagccc cttccgggcc
     4201 gaggccgggg atcgtgatct cgcgccgcag ttcgtgctgc cgctcgtcgt gcgcatcgag
     4261 cgggcggcgc cgccgcaccg taccgacgcg ctggagaccg cggcccgggc ggtgctggtg
     4321 atgctcgggg acgagcggtc gaccggtgac ggcgagtggg cgcgggcggt gcgggactgg
     4381 caggacgcgc ggatccgcaa ggtcgtgcgg cgggcccgcg gcgccgagtg gcggcgggcc
     4441 gaggcgctgc ccggcatcac ggtcggcggg aaaacggccg aggtgcgggt gtttccgccg
     4501 gtgccgttgg acggctggcc gaaggacctg gcccggctcc aggtctccgg caccgacctc
     4561 gacgaccccg agccgccggc cggggcggac cccgccgcgc cggtgctctg gatgaacccc
     4621 gacctggaca tgtcggcggg caaggcgatg gcccaggccg gacacggcgc gcagctcgcc
     4681 tggtgggaac tgtccgacgg cgagcgggcg gcgtggcgcg acgcggggtt cccgctgtcg
     4741 gtacgcaccg cggacccgtc ccgctggagc ggcctgacca ccggcggcct tccggtggtg
     4801 cgcgacgccg gcttcacgga gatcgcgccg ggctcgtgca cggtggtggc ggaccacccg
     4861 gcgctgcggc gctagccgcc cgccgcccac gcgaaagctc agatgttgct ctgaagacgg
     4921 cccggccggg gttcggcccg ggccgggtgg gcgatacccc cgacatgtgc gcacgagggg
     4981 aggtggcggc catggagccg atcatgcgac tggggacggg catcggatgg cggccggaga
     5041 tcgcggacgt cgtcgagcgg atgcccggca tcgactgggt cgaggccgtg tccgagaacc
     5101 tgtgtcccgg gcacctgccc gactcgctgc tgcggctgcg ccggcgcggc gtgaccgtcg
     5161 tgccgcacgg cgtctcgctc gggctcggcg gcgccgagcg gccggacgcg gggcggctgg
     5221 cggcactggc ggagcgggcc ggggtactcg gggcgccgct ggtcaccgag cacatcgcgt
     5281 tcgtgcgggc gggcggggcg ccggccgcgt cgcccctgct ggaggccggg cacctgctgc
     5341 ccgtgccgcg cacccgtgac gccctcgacg tgctgtgcga gaacgtgcgc atcgcgcagg
     5401 acgcgctgcc cgtcccgctc gccgtggaga acatcgccgc gctcttctcg tggccggacg
     5461 aggagctgac ggaggggcag ttcctgtacg agctggccga ccggaccggc gtgcggctgc
     5521 tgatcgacgt cgccaacctg cacaccaacc acgtcaatcg cggcgaggac ccggccgagg
     5581 cgctcggtga actgcccctg gaggccatcg cctacgtcca tgtcgcgggc ggcttcgaac
     5641 gggacggcgt ctggcacgac agccacgccc accccgttcc gcggccggtg ctcgacatcc
     5701 tgaccgacct cgcctcgcgc gtcgcaccgc cgggcgtgct gctggagcgg gacgagaact
     5761 tccccgaggg ggaggagttg gcgggcgagg tggcgtcgat ccgcgcggcc ctcgccgagg
     5821 gacgggcggg cggggcaccc ggcggcccgg acccggcggg gccgcaccgg gccgtacccc
     5881 gaggtgccgg cgacgtcgcc ggtgccggcg acgccgtacg gcagcggctc ggacgcgcgc
     5941 agcacgcgct gctggcctcg ctggtggcgg gggcgcccgt gcccgagggg ttcgaccggg
     6001 cccggctcgg ggtgcaggcg cgggcgctgg ccggcaagcg ggcggacgtg gtcgcgaagg
     6061 tggcgcccga actgccggtg atcctgggcc cgcggtaccg gccggccttc ctcgcctacg
     6121 cgcggacccg cccgatgacc ggcggctacc ggcgggacgc cctcgacttc gccgagcacg
     6181 tgctgcgggc cggggcggga ccggaggaga ccttccggga tgtgcggcgg gagttgcggg
     6241 agtggtggcg ggaacgctcg ggaccggtac cgcggtcggc ccggcccggg gcccggctgg
     6301 cccgtgcgac caggcgcgtc ctgctgcgcc gttgaacctc gcagcgtcgc gggggaccgt
     6361 cgccggacgg aacgtcacca acccgcacca ccgcgtcccg gaatgtgaac agggcatggc
     6421 gcgggtgaaa gcctttgaca tacaagtacg tcatgttctg ggtccttttc ctcctgtcgg
     6481 cctgggccgt ggccggtctc gcgtgtctgc gcctgtgcct ggccgccgtg cgggccgcgg
     6541 cagcggccgc ggccgccccg cgctccgtcg cccgtgagca cgcgctgacg ctgtacgagg
     6601 cggcgttcct gtccggcggc ccgcggcggg tggccgacct gacgctcgtg tcgatggcgc
     6661 gtcagcggcg gctgctgctc gcgcacaccg gctgggcgac ggtcgtggat ccgtgcgggc
     6721 gcgacgacat ggagcggtcg gtcatcggag cgatagggcc ggaggggcag tcgcggatag
     6781 cgccggtacg ggccgccgcg gccaccgccg acgccgtacg aggcctggcc gaccggctgg
     6841 tgggcgcggg cctcgccgtg cccgacggcg gcgccggcgg cgtcgcggac ggggtgcggc
     6901 gggtgcgggc cgccgcggcc accgtgtgcg cgctcggcct cgccgccctg gccctgcccc
     6961 tccccgccac cgagccgcgc cttctggtcg ccctctggtt cacgctgccg ctcgccctga
     7021 ccctggggtg cctcgtcatc acgcgcatgg aggtccaccc gtactcgcgc tgggcctccc
     7081 ccgccgggca gcggctgatc ggcgccctcg tgcagcgggc cgacggcacg gcggacgacc
     7141 ggaccttcct cacctcggtc gccgtgcggg gcgtccacgc gatcggcgaa ccggacctgc
     7201 gtgcggcctt cgcacaccgg gaggagtacg ccgaggagca ccgcgagcgc cgggtctgac
     7261 ccgccgggcc cgcgggggcg cacggaggca ctcggcgccg acacccgcgg ccggtgcttg
     7321 ccccgcacct ccgacgcgcc aaacatccct tctgtcaccc ccgcgccacc gaagggatac
     7381 gcgatgcgag ctgccgccct ctactcggcc gccgggtcct tgctgctgac caccctcacc
     7441 gccggcccgg cccgggcggc gaccccggcg ggccccgagt cccccgaggc acgcggcacc
     7501 gccgtggccg ccgggcgcgc ggcggcggcc gggatcacgt tcggctcctg cccgaaggcg
     7561 gaggaactgc cgggcggcat ccgctgcggc accgtcagcg tgcccctgga ctacgcgcac
     7621 cccgacggca agcagatcga actcgccgtc agccgcgtac cggccaccca caaggacccg
     7681 gacaacggca agcacaaggt ccccggccag ggcgccctcc tctacaaccc gggcggcccc
     7741 ggcgcctcgg ggctgtactt cccgctggtg ggcatggtgc ccgagtggaa gcgcatcgcc
     7801 gccgcctacg acctcgtcgg ctacgccccg cgcggcgtcg cgccctccgc gccgctgtcc
     7861 tgccaggacc ccggcgactt cttcaaggga ccccggcccg ctccgacgca gccctcggac
     7921 gcgtacaagg cggagcgcgc cgccgaggcg gagacgtacg cgcacgactg cgccgcacgc
     7981 gccggggacg cgctgcgcca ctaccactcg ctcaacaacg cccgtgacct ggaggtcgtc
     8041 cgcgcggcgc tgggcgagcg gcggctcacc ttcatgggcg cgtcgtacgg cacctacctg
     8101 ggggcgctgt acgccgagct gttcccgtcg cacgtgcggc ggatggtgtt cgacgcggtg
     8161 gtgaacccgg accccgagca ggtctggtac cgcaacaacc tcgaccagtc cgaggcgttc
     8221 gaggaccgct gggacgactt caaggagtgg gtcgccgagc acgacgccga gtacgggctc
     8281 ggggacacgc cgaggaaggt gcaggacggc tacgacgagg cgagcgcgcg gctggccaag
     8341 gagccggcgg gcgggacggt ggggcccgcg cagttgcagg gggcgatgct gaaggccggg
     8401 tactacgacg actactggcc gcaccgcgcc gaggcgctgt cggcgtacct gaagggcgat
     8461 ccgcagccgc tggtcgacca ggcgggcacg cgcaccgagg agggctcggt cgcggcggag
     8521 aactccaacg ccgtgtacac ggccgtcgag tgcaacgacg cgccgtggcc gaccgacttc
     8581 cgggtctggg accgggacaa cacgcggctg gcccgccggg cgccgttcga gacctgggac
     8641 aacgtgtggg cgaacctgcc gtgcgcctac tggcgggcgc cccggcagca gccgctcgac
     8701 gtgcgcaccg cgccgggtga gctgccgccg acgctggtcc tggccgcgga gcgcgacgcg
     8761 gcgacgccgt acgagggcgc gctggagctg cggcggcggc tgtcgggctc ggtcctggtg
     8821 accgagcggg acgccgggac gcacggcatc gcggcgggcc cgaacgcctg cgtcaacgac
     8881 cacctggagg cgtacctgct ggagggccgc ctcccggcgc gggacacgtc gtgcgcccca
     8941 cgcccggagc cgcggcctca gccgcagccg aggacctgac taggcgagcc cgacgaccaa
     9001 ctcgccgatc tccttgcgcc gccccgtgct gcatcccccg ggggacaacc cccggacccc
     9061 cggccggccc gacagccacg cccgccggtc aggcgagccc ggcgaccaac tcgccgatgt
     9121 ccttgcgacg ccccgtgtag aaggggatct cctcgcggac gtggcggcgg gcctcggagc
     9181 cgcgcaggtg gcgcatgagg tcgacgatgc ggtgcagttc gtcggcctcg aaggcgagga
     9241 tccactcgta gtcgcccagc gagaaggagg cgaccgtgtt ggcgcgcacg tccgggaagc
     9301 cgcgggccat cttgccgtgg tccgcgagca tgcgccggcg gtcctcgtcg ggcagcaggt
     9361 accagtcgta cgagcgcacg aacgggtaga cgctgatgta gttccgcggc gtctcgtcgg
     9421 ccaggaaggc cgggatgtgc gagcggttga actcggcggg gcggtgcagc gccatgttcg
     9481 accagaccgg ctccagcgcg cggcccagct tggtgcggcg gaagaggttg tacgcctcct
     9541 ggagctggtc ggcggtctcg gcgtgccacc agatcatgag gtcggcgtcg gcgcgcaggc
     9601 cggacaggtc gtaggtgccg cggatcgtca cgtccttcgc ggcgagccgg ccgaacaact
     9661 cctggacctc gtcggcgtat ccggcgcggt cctcggggag ggtgtccttg agcttgaaga
     9721 cggaccagag ggtgtagcgg atgacctcgt tgaggtcctt ggccagcttg cccttgttgg
     9781 gggtgcgctc ggccgcaggg gtggaggcgt cgtcactcat ggccctattc tcccgctccg
     9841 ccgtgcaggc tctgcaccgg gtgggccgtg agctcctcca caccgcgcag gtcgccccgg
     9901 acctggtcga cggcggcgta cgcgctcgcg atgctcgccg ggatgccgac gccgtcgtag
     9961 gccgcgccgc acaccgcgag gcccgggagt cccgcgacgt gctcgcggac gcgggccacg
    10021 cgcgcgtggt ggccgaccgg gtactgcggc aggccgtcct gccagcgggt gacgcgggtg
    10081 gcgaccggcg cggcggccag tccggtggcc tcgcgcaggt cgtgccggga gacggcgacg
    10141 aggcccgcgt cgtcgcggcc gaggatctcc gtgtcgccgt accggcccac ggaggtgcgc
    10201 aggacgacca ggtccgggcc ctcgtcggcg atccagcccc acttgcggga ggcgaaggtg
    10261 gacgccttga tggtgtgccc gtcgacgggc ggtacgagga agccgctgcc ctcggggagc
    10321 gcggcggcgt ccgagcggcg gtaggcgagg gtgatcaggg ccatcgaggc gtactccacc
    10381 gcggacagct cggccgcggc ggcgggcgcc tcggcgcgca gcagctcggc ggcggggcgt
    10441 gcgggcacgg cgacgacgac cgccgcggcg tgcagcaccc ggtccccggc gacgacccgc
    10501 cagccgccgg ccgtgtgccg cagctccgtg acgggcgcgc cggtgacgat ctcgccgccg
    10561 cgcgcgcgga ccgactcggc gacggcgagc gggagcgtgc cgacgccgcc ctcgatgccc
    10621 gtgaacaccg gcccgctcgg cggggaggtg gccgtgcggc cctggagcgc gcggaccgcc
    10681 tcggtgaggg aggtgtgggt gcgggcggcc tcgaagagct gcggcacggc cgagcgcagg
    10741 gagatgcggt aggcgtcgcc cgcgtagacg ccgcccagca gcggttcgac gaggcggtcg
    10801 acgacctcgc ggcccaggcg cgccgcgacg tactccccca ccgccacgtc ctcgccgacc
    10861 tcggtgcggg gcagttcggc gtcgcgctcg atgcgggcga gcccctcctc ggagagcacg
    10921 ccggacaggg cggcggcggt gccggggacc cccatgacgt ggcccttggg catggggcgc
    10981 agggcgccgc gggtccacag ggaggccgtc gcggtggacg gcggctggag ccggtcggcg
    11041 agaccggcgg cgcgggccag gccgacggcc tcggggcggc gggccagcat cgactcggcg
    11101 ccgaggtcga cgcggactcc ggcgatctcg ccgggcagca gcttgccgcc gacgcggtcg
    11161 gacgcctcca ccacggtcac ccggacgccg tgctccagga ggcggtgggc ggcggccagt
    11221 ccggcgatgc cggctccgac cacgaccacg tggtccgggt ccgcgggccg ctcacccgcc
    11281 gggtcctcac tcgggttctc acttgcgcac atgtccctca gcgtctcaga ccgcg
//
