LOCUS       NZ_CP043317            24145 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Streptomyces olivaceus strain SCSIO T05 chromosome, complete genome.
ACCESSION   NZ_CP043317
VERSION     NZ_CP043317.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces olivaceus
  ORGANISM  Streptomyces olivaceus
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8458055)
  AUTHORS   Zhang,C., Ding,W., Qin,X. and Ju,J.
  TITLE     Genome Sequencing of Streptomyces olivaceus SCSIO T05 and Activated
            Production of Lobophorin CR4 via Metabolic Engineering and Genome
            Mining
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8458055)
  AUTHORS   Zhang,C., Ding,W., Qin,X. and Ju,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2019) Key Laboratory of Tropical Marine
            Bio-resources and Ecology, South China Sea Institute of Oceanology,
            Chinese Academy of Science, NO.164 Xingang Road, Guangzhou,
            Guangdong 510301, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 28-MAR-2017
            Assembly Method                   :: HGAP v. MAR-2017
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 8458055.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015244315.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 18:39:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,352
            CDSs (total)                      :: 7,265
            Genes (coding)                    :: 7,077
            CDSs (with protein)               :: 7,077
            Genes (RNA)                       :: 87
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 188
            CDSs (without protein)            :: 188
            Pseudo Genes (ambiguous residues) :: 0 of 188
            Pseudo Genes (frameshifted)       :: 106 of 188
            Pseudo Genes (incomplete)         :: 98 of 188
            Pseudo Genes (internal stop)      :: 7 of 188
            Pseudo Genes (multiple problems)  :: 23 of 188
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:52:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1966770
            Orig. end                         :: 1990915
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP043317.1.
            Bacteria and source DNA available from South China Sea Institute of
            Oceanology, Chinese Academy of Science; 164 West Xingang Road,
            Guangzhou 510301, China.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24145
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="15"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24145
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24145
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14145](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14145
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            723..2054
                     /db_xref="GeneID:69760041"
                     /locus_tag="FYC74_RS08205"
     CDS             723..2054
                     /codon_start=1
                     /db_xref="GeneID:69760041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030675.1"
                     /locus_tag="FYC74_RS08205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF58 domain-containing protein"
                     /protein_id="WP_194275395.1"
                     /transl_table=11
                     /translation="MPRQPAPAVVRALEGRTSPVQPPSPPPDGPRPGERTLRLLAVAAI
                     ALSAALVTGHAWLFALAAAPLVLLALALPRAYARRIETSATVEPARCFEGDTVTLRIAV
                     AHDGDAVRLDPGATLGPGLSLDEVVVGSASVTLRHTALHWGRWSLGPVDLDVYDAGGTV
                     RRTVRVEAAEVSVFPHATEARFTPIPARLPQRLGEHASPQTGEGVEVIGVAPWVPGERQ
                     RRIHWPSTTRRGSIQLHRFAAERAADAVMLIDAFGDVVDPATGVSSLDETVRAASGLAR
                     AYLRTHDRVGVVSTGGTTRWLAPGTGDAAFYRIVESVLDVRKDRRFDGPGLERVPPPAL
                     PEGALVYVFTPLSDARILDVLRDLRSRGRRPVVVEIPSGDPQVEDGDETGELGLRLWRA
                     ERDAMRFTLRDSGVPVVRHAVGESLDLALAPLLSGRVGGRGRAG"
     gene            2051..2632
                     /db_xref="GeneID:69760042"
                     /locus_tag="FYC74_RS08210"
     CDS             2051..2632
                     /codon_start=1
                     /db_xref="GeneID:69760042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326059.1"
                     /locus_tag="FYC74_RS08210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_194275396.1"
                     /transl_table=11
                     /translation="MTTATALDRRVGLREYLGYWVGTLPVRVIAVAAVVMAWRPWSAVG
                     TAGDAVVPGCVIAFAVWAAPALDRRPSLRSARWSYRLEHHRTTLLAGSVVVLAAFGEPT
                     WWEGASVVVLLVAYLMASETWPWRRGRGTAHVWVEAAAACAGAGVVAAAAAAPVTGTGS
                     SLGRVMAAGAVAALAVAGGALLRARWRGVR"
     gene            2986..4341
                     /db_xref="GeneID:69760043"
                     /gene="dacB"
                     /locus_tag="FYC74_RS08215"
     CDS             2986..4341
                     /EC_number="3.4.16.4"
                     /GO_function="GO:0004175 - endopeptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0009002 - serine-type D-Ala-D-Ala
                     carboxypeptidase activity [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69760043"
                     /gene="dacB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007445417.1"
                     /locus_tag="FYC74_RS08215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="D-alanyl-D-alanine
                     carboxypeptidase/D-alanyl-D-alanine-endopeptidase"
                     /protein_id="WP_194275397.1"
                     /transl_table=11
                     /translation="MTGTPDETPTNAFTPGGRRRHRKARVSRIGGRRALVLAMAVPVAS
                     ATLAGTSAFAADNTGTQAQGVSVDDLAADDAQLVKNLEERVADERLGNDVSGVVLDADS
                     DTALWDHNGATALMPASNAKLATATTALTLLGANHEFTTKAVYGEGTLTLVGGGDRTLT
                     SDDLAEMAKTAADGLKAAGRSDVQVRIDDSLFADPSLAQGWNEGYYPTEITPVRSLVVD
                     GAAVDDTSIDAGKVFAEKLAEQGITVDGEVSRATTKDSDVPVAQHKSAPLSEIVKTMLK
                     TSDNNIAETLLRMSAVELGKPGTFESGTALVRQVLSSYGISLDNFEMHDGSGLSRDDRI
                     PAATLAQLLDSITESPALSSILEGLPVAGEAGASLGPEWGRFDDPNSECAVGKVQAKTG
                     TLTGAIALSGVTKTEDGDWRIFSFIENNSTADPTDIKDAMDGLAATVNGCWA"
     gene            complement(4751..5155)
                     /db_xref="GeneID:69760044"
                     /locus_tag="FYC74_RS08220"
     CDS             complement(4751..5155)
                     /codon_start=1
                     /db_xref="GeneID:69760044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020140619.1"
                     /locus_tag="FYC74_RS08220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_194275398.1"
                     /transl_table=11
                     /translation="MTPWSLLDIDRALRASWAADTCSPDDRERVEWLPGNPAWGHCDIT
                     ALIVNDIFGGDLVVGEVYLDGAQRNFHWWNKLPNGIELDLTREQFQLGETVTAARVVER
                     PPGPLPRRYEEYLLLRERMTEHLGPLPEPA"
     gene            5265..6278
                     /db_xref="GeneID:69760045"
                     /locus_tag="FYC74_RS08225"
     CDS             5265..6278
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69760045"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003963504.1"
                     /locus_tag="FYC74_RS08225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_194275399.1"
                     /transl_table=11
                     /translation="MRILVMGGTWFLGKAIAETALARGWDVTTFNRGRSGVDVPGVEAV
                     HGDRTVQEDLYKLAQRGPWDAVVDTSSSELPPRDVRLAATALAGAARRWVHLSTVSVYE
                     RWPHEPLTEDSPLLRCPADADESFGYTGEDGSPTKYGFQKAGGERAVVEAFGDEAVLLR
                     PGVILGPGEYVGRLPWWLERAKRGGRMLAPAPAEQRIQPVDVRDVAGFAVQQAAGTGRG
                     AFNVAHPDGISFGGFLTECLRVTGGDGTPVWADPTVLAEHRVKQWTEMPLWRTHAGVWS
                     VDARRAVEAGLRCRPIADTVRDTWTWWEGNGRPVDHPRRAEHGIAAEKETRILASL"
     gene            complement(6354..7679)
                     /db_xref="GeneID:69760046"
                     /locus_tag="FYC74_RS08230"
     CDS             complement(6354..7679)
                     /codon_start=1
                     /db_xref="GeneID:69760046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003963503.1"
                     /locus_tag="FYC74_RS08230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA-binding protein"
                     /protein_id="WP_194275400.1"
                     /transl_table=11
                     /translation="MRSAPRTLLAKLCDRDNLTYRRFDKKFNETGVRLFGNSTNNPTCG
                     ETQFRRWTGGKLTGLPGPQTCHVLETMWPGYTAAQLFAAPPADDPQVPAFDLEERVQMT
                     AREAHDGADATAAASISDNTIDELRDQVVSLARRYHGLSAADAYEAADTLRRDIERHRD
                     RTQVPFQQQTLMILNGQTAALLAVAAFDLGYFPSARTLARATAVYAESTRFAPLQAYAD
                     GTLAYIAYHSGEPGEALSKSRRALSYGGLGDVAQRRLNAIAARAYAHLGDVTSARRTIR
                     LSEDRGEEARDELHDEVGGEFGFSEERLAMSNSTTALLMGDPEQAETEAGRAIALLGQR
                     ARGERSTHVLAGAAADLAYARLLSDNVEGAAEALAPIWEVPAEQRKTGVVVRTARIGRH
                     LSRSRYHGSQLPSQLREQVEEFTRVSPPYRLGPSVALLAIGF"
     gene            7990..8496
                     /db_xref="GeneID:69760047"
                     /locus_tag="FYC74_RS08235"
     CDS             7990..8496
                     /codon_start=1
                     /db_xref="GeneID:69760047"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FYC74_RS08235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_194275401.1"
                     /transl_table=11
                     /translation="MAPAATVVKAPPSPQPTSLPFLQPTFLPSPSSPLVPRRARRREDL
                     QRIVVLLRPGLPVDGAFDVVVAVLGDRAAPAEDDVPALAERFLGAGRVQGHRPAPVHAG
                     AGKQSGEPGLGAYLVAPAHDPLGQPTRTDGTALLGRRLRRLALALTAQDLPELLQSGEG
                     GRRRA"
     gene            8489..8962
                     /db_xref="GeneID:69760048"
                     /locus_tag="FYC74_RS08240"
     CDS             8489..8962
                     /codon_start=1
                     /db_xref="GeneID:69760048"
                     /inference="COORDINATES: protein motif:HMM:NF040050.4"
                     /locus_tag="FYC74_RS08240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6302 family protein"
                     /protein_id="WP_194275402.1"
                     /transl_table=11
                     /translation="MPEPTPPPTEPDVTVMPPAEAYDFDYFRCRVDAGLLSRSIAVRVF
                     RIPLLAVPVGGSRRGGWFGAGDLAGALAVRQVLAALNGFPCARITWQRIPSCSYAVEWG
                     DRPPATWLDDNERLAFYGLTWPDLAPGRPHRSRASAVSSGSSNTARPYSCGPH"
     gene            9080..9502
                     /db_xref="GeneID:69760049"
                     /locus_tag="FYC74_RS08245"
     CDS             9080..9502
                     /codon_start=1
                     /db_xref="GeneID:69760049"
                     /inference="COORDINATES: protein motif:HMM:NF024970.5"
                     /locus_tag="FYC74_RS08245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_228123314.1"
                     /transl_table=11
                     /translation="MNERITVAGPRSDGMPRPQDPARVGVLRRIAAARLKHRGLDAMTG
                     DVLLISSELLTNALLHSGATEITLNLTVHDGYLRITVTDGMPGRAKRRKADDEAETGRG
                     LGLVEVLAEQSGGTWGTSEHGAATWCSLRVPAGQRR"
     misc_feature    9721..9735
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     gene            9788..9922
                     /db_xref="GeneID:69760050"
                     /gene="fxlA"
                     /locus_tag="FYC74_RS08250"
     CDS             9788..9922
                     /codon_start=1
                     /db_xref="GeneID:69760050"
                     /gene="fxlA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FYC74_RS08250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_194275403.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 3.3e-08, bitscore:
                     32.1, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVPVPAEEWELDTTVTRAPVPIVEACGTGDGCAKTCASSCASS"
     gene            10001..12994
                     /db_xref="GeneID:69760051"
                     /locus_tag="FYC74_RS08255"
     CDS             10001..12994
                     /codon_start=1
                     /db_xref="GeneID:69760051"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.5"
                     /locus_tag="FYC74_RS08255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_194275404.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.3e-152,
                     bitscore: 507.9, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 8.2e-20, bitscore:
                     70.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARPTFRRHGDVLVLRAAAMPVRARPDDWPDVESLDGCCAWLARV
                     WCDDSFVVPLRAASPRLAGFVERILDGDTVPLKRVRSATLSVATYLLRASSRATPFGLF
                     AGVALADIGPVSARLGTGHRAVARPDTLWVDHARRALQRRADVLPHLTLRVSTLSFRRG
                     DTVCTPRPGGRLASAPVTRPLAVLLEAAAAPAPGRLLLEALSEQAGGTSEQAVRLLEQA
                     LEDGYLTSDLAADMTVEDPARHIVRTLRSYVETLEPDTVRIIDRLEETGQALALHNRSG
                     PGAAPGLRDLADKGMRELQAADCQSRISLDLCLDAQVSVPHQVLDEVERAAHTLVRLTR
                     AQGESPAWAAYQTHFWEHYGAGVLVPVREAADLAAGLGFPADYPMSVWNQAPPTVLPRD
                     EQLAARAMRAAVTGDREIVLSERDVDALAGDGPERPSAPHVEVGFRIRAVSEKAVSSGD
                     FTLDVRPAWTAGVLSGRFTSLLGRRLSDLYRTLPTMTRGALPAQLSFVPDFPHAQNVSR
                     IPALLPHVIPVGETRTATNGVIDIDDLAVLSTGEQLHLVSTSRRRIVEPHVLHPLALEK
                     QAPALVRFLAQLGRGFATAWTAFDWGPVAAALPCLPRVRHRRTVLAPARWRLSAADLPS
                     GPYGTAWHAALDAWAATWRCPARLHLLDDDRTMLLDRTEPLHARLIHQHLRRHPHAVLT
                     EAVHDDELGWLGHAHEFTVPLTTTRPQAPHPDLTRAPVVTNRDLAHPGDPGQRWTQAKV
                     FTHPTAMDEILTLRLPRLLDALGTSQAWFVRYRSLQETDHLRIRVPTGGPGSLEATLRA
                     LSDWTKRLAEDRLASRLVLDGYRPETGRYGTGAAMEAAEDVFVADSLVARYALTDIPGL
                     KRETVCALNMIDLAEGFLGTQEGRAWTARTPAPGKPRPEVTRQTIDKAETGPLLHTTPR
                     LAHAVARRRAALGAYRSHTGASRLEQALESLLHMHHNRLLGPDRDSEAASRHAARQACR
                     SLVMRATP"
     gene            12991..14145
                     /db_xref="GeneID:69760052"
                     /locus_tag="FYC74_RS08260"
     CDS             12991..14145
                     /codon_start=1
                     /db_xref="GeneID:69760052"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.5"
                     /locus_tag="FYC74_RS08260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_194275405.1"
                     /sec_met_domain="LANC_like (E-value: 1e-40, bitscore:
                     138.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSHDDHDDLGGGLAGNALYAMVIAREEDDWTVAHAAARAITSHPI
                     TAHPAHANLYRGAPAVAHVLHTAGHRAYARSLAALDAETAAIAADRLDAAHHRMDSGRP
                     PRLREYDLISGLTGLGAYLLHRGHDDVLECVLRYLVRLITRPLTVDGHQVPGWWAATDP
                     RDSAGTGRFAHGHANFGIAHGVTGPLALLALARRAGRTVDGHDDALAEGVAHLTAWAQP
                     LDNGSTGWPELLPLDTYRRGPQPGAAPGRPSWCYGTPGIARALQLAALALHDNAARRLA
                     EHTMLQTLTDTRQTNQITDASLCHGWSGLLLASTRTASNAALPDLTTALSALHTHLKPD
                     ATRHRTTKDTGLLTGTPGILLTAHTLNTTSRPVSPGWETCLLLN"
     gene            14159..15355
                     /db_xref="GeneID:69760053"
                     /gene="fxlM"
                     /locus_tag="FYC74_RS08265"
     CDS             14159..15355
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69760053"
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010473477.1"
                     /locus_tag="FYC74_RS08265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_194275406.1"
                     /sec_met_domain="PCMT (E-value: 4.5e-40, bitscore: 136.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQTPTADQLCNRLVDDILSERDLPSDVEQAMRTVPRDTFLPGID
                     LKNAYTDQAVTIKDNPGQPLPLSCASVPSVVAMMLGQLTARPGDNVLEIGAGTGYNAAL
                     LAELVGGGRVTTVDIDSDVALHARTTLNTAGYERVTVIERNGLLGAHEHAPYDRIIATV
                     GVWDIPATWWDQLADGGRLVLPLRWRGQTRSVALTRHGNQLVSDGMELCGFVPIIGQNG
                     EKTASLNAADTLRLHYDQDQTINPDALTHTLQADKPAREVLSAQRIGGEESFDGVWLRA
                     TAHDDRVCRLETTPEAMEQALIRRPATPARTPALIDDASLAYLTVTREDADPQRPFRLG
                     ATAYGPRGEELARDLVAHIDAWGSDRLAVPRLTITPSDTGDAPGHTISKPESRITLTY"
     gene            complement(15719..16450)
                     /db_xref="GeneID:69760054"
                     /locus_tag="FYC74_RS08270"
     CDS             complement(15719..16450)
                     /codon_start=1
                     /db_xref="GeneID:69760054"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FYC74_RS08270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_194275407.1"
                     /transl_table=11
                     /translation="MNPGSLLSDLPGAASVSGLASAWRWSPNPMFTFTAALSIDGRHNL
                     QVNVRGPYDEGLVTALLAHTRAHDGTFVEQGRPLVAVGGFQHDGTAFDTVGVAAPEVHD
                     YHATENPELSAVTYAVFPAYASEISGRESEEEAWGRFRKMLQPNKLDRTEVPFVKMRYD
                     NTRTQSMSKGDARGFAPLDTLVRELGLLDGAPGSFVEWENRRGAVWRADSNSDGLELTH
                     DGTGGTVDTGQLQAIARTSVQ"
     gene            complement(16796..17140)
                     /db_xref="GeneID:69760055"
                     /gene="cas2e"
                     /locus_tag="FYC74_RS08275"
     CDS             complement(16796..17140)
                     /GO_function="GO:0004521 - RNA endonuclease activity
                     [Evidence IEA]"
                     /GO_process="GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69760055"
                     /gene="cas2e"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004939431.1"
                     /locus_tag="FYC74_RS08275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I-E CRISPR-associated endoribonuclease
                     Cas2e"
                     /protein_id="WP_194275408.1"
                     /transl_table=11
                     /translation="MSAGTTVVVLIAAPPGLRGHLTRWFVEVAAGVYVGNPNPRIRDRL
                     WTVLAERIHDGQAVMIEPAATEQGWSARTAGRDRWTPVDFDGLTLMARPRQNGQPWRPT
                     NEVKQNGMIT"
     gene            complement(17137..18111)
                     /db_xref="GeneID:69760056"
                     /gene="cas1e"
                     /locus_tag="FYC74_RS08280"
     CDS             complement(17137..18111)
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004520 - DNA endonuclease activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /GO_process="GO:0051607 - defense response to virus
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69760056"
                     /gene="cas1e"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541931.1"
                     /locus_tag="FYC74_RS08280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I-E CRISPR-associated endonuclease Cas1e"
                     /protein_id="WP_194275409.1"
                     /transl_table=11
                     /translation="MAEPWWRTGPQDVHRLEDRISSLYAERCHIDRDDNAIVLVNKART
                     VHVPAAWLAVLLIGPGSRVTHPAITLLADSGTAVCWVGEQGVRLYATGTSTARGSQLQL
                     RQAWLVTRPKERVGVARRMYDMRFPGEDTTGLTLQQLRGREGTRIRKLYAQHAERTGVP
                     WTKRDYKPGDAFAAGDDVNRLLSAANSALYGISHAAITGLGASPALGFVHTGNALSFVL
                     DIADLYKAEFTIPLAFDLAAQGLTSERDARTALRDAAVQGKLLPRIVADIKQLLVPGGS
                     DLPDEDLGALWDDGDTVVSGGRNWSATHHLDIIPEPTSAEAAP"
     gene            complement(18104..18889)
                     /db_xref="GeneID:69760057"
                     /gene="cas6e"
                     /locus_tag="FYC74_RS08285"
     CDS             complement(18104..18889)
                     /GO_process="GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69760057"
                     /gene="cas6e"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569282.1"
                     /locus_tag="FYC74_RS08285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I-E CRISPR-associated protein
                     Cas6/Cse3/CasE"
                     /protein_id="WP_194275410.1"
                     /transl_table=11
                     /translation="MAYLSKIALNPRRRAAVSLLSSPHRLHAAVLSGLATQPVTERVLW
                     RLENSTPHRADVLVLTESRPSWAHLVDDAGWPGADGGAPLIADYTPLLERLVRGREFGF
                     RLTANPVRNVPRPDRPSEQQATRLKEAADNGSRPRGARVAHRTAAQQLDWLLSRCERHG
                     FTIPDATVTPPAPGLHSTDQDLSAGPAVTIVGRDILRFRKHSDGPRVTLSTATFEGRLH
                     VTDPDALRTTLLAGIGPAKGYGQGLLTLAPLRTTQANHG"
     gene            complement(18894..19685)
                     /db_xref="GeneID:69760058"
                     /gene="cas5e"
                     /locus_tag="FYC74_RS08290"
     CDS             complement(18894..19685)
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_process="GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /GO_process="GO:0051607 - defense response to virus
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69760058"
                     /gene="cas5e"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569281.1"
                     /locus_tag="FYC74_RS08290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I-E CRISPR-associated protein Cas5/CasD"
                     /protein_id="WP_194275411.1"
                     /transl_table=11
                     /translation="MTGTDHAVLVLRLAAPLQSWGGPSQYNRRETRPRPTKSGILGLLA
                     AAEGRSREASLTDLVDLRLGIRVDQPGTLLRDYHTYSDYRGLPLLSAKTNTKGQQTRTT
                     PAKHTGVTQRFYLQDAVFVAALRGPKALVQSLDEAVRNPHYPLSLGRRSCPPTGPVGLG
                     LHADAPLEQALTDVPWQAGAHRRRQARTTTVALEATIEDPAGDQLTVDVPDTYDLKTGT
                     RFGRRAVRHLWVTVPTGRASDATDTETAGQPDHDPFALLGW"
     gene            complement(19682..20860)
                     /db_xref="GeneID:69760059"
                     /gene="cas7e"
                     /locus_tag="FYC74_RS08295"
     CDS             complement(19682..20860)
                     /GO_process="GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69760059"
                     /gene="cas7e"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569280.1"
                     /locus_tag="FYC74_RS08295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I-E CRISPR-associated protein
                     Cas7/Cse4/CasC"
                     /protein_id="WP_194275412.1"
                     /transl_table=11
                     /translation="MSRPTLFVEVHILQSLPPSNVNRDDSGTPKQAVYGGARRARVSSQ
                     AWKRATRTEYAKDTPEADRATRTKRIAALLVHRLARPTDQDGAGLNTEQAERLAAALLE
                     PLGITKSAKKDDQSAYLLFFGKTQLDSLVRLLDGRAAELAALPDDDLKAEVKKLSVVKS
                     LSTGHPAEVALFGRMVADLPALNVDASVQVAHALSTHAVRTEFDYYTAVDDENTDDHGA
                     GMIGTVEFNSSTLYRYAVLGVHQLRDNLTDAEETRSAAVRFVDAFTRSMPTGHQNAFAH
                     RTLPHLVLLTLRTDQPVNLVSAYEEPVTGATGLASESVVRLADELRAVGETWGNAPLRT
                     LATYTAEGDKVTEVFGSSMPFPALLDSVGELVGQWLADGGITPAATAEADAR"
     gene            complement(20971..22155)
                     /db_xref="GeneID:69760060"
                     /gene="casB"
                     /gene_synonym="cse2"
                     /locus_tag="FYC74_RS08300"
     CDS             complement(20971..22155)
                     /GO_process="GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69760060"
                     /gene="casB"
                     /gene_synonym="cse2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569279.1"
                     /locus_tag="FYC74_RS08300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I-E CRISPR-associated protein Cse2/CasB"
                     /protein_id="WP_194275413.1"
                     /transl_table=11
                     /translation="MTSRGSTSASRAAANRLRLFFWEETAGDWHSASSEGRRPEFPEYV
                     TRGLRALREGLGREAGTVASMLPVHRVFLRDDGSDRLPEEYVAEHHTLTLFGLHQHAAS
                     EPVHRPGVGLGTACLLLRRSEVLTDSAVERRLTAAATSQDLQELAQHLQRLVPLLRRAG
                     IGLDYTRLFHELTRWDSPQRDRVLRSWGLQYTDPGTPSQEGDPDDTGAEQTPYWGTFDP
                     ESGETGAELAALRSGTGREPGTVAAMWPFHRTRMESEWRDKGSLTRDLAAEHIALTLFA
                     RHQQSQSRRMHIAGNSPGTAADLLAHRNAADGEGKAATAALERRFGTLLTSADTDELAM
                     HLRSLVPLLNRAGIGLDYNLLRTALRTWDDPRRPDDATGYRQQWDHDFHRAASA"
     gene            complement(22152..23843)
                     /db_xref="GeneID:69760061"
                     /gene="casA"
                     /gene_synonym="cse1"
                     /locus_tag="FYC74_RS08305"
     CDS             complement(22152..23843)
                     /GO_process="GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69760061"
                     /gene="casA"
                     /gene_synonym="cse1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569278.1"
                     /locus_tag="FYC74_RS08305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I-E CRISPR-associated protein Cse1/CasA"
                     /protein_id="WP_194275414.1"
                     /transl_table=11
                     /translation="MADEGDLVHDGWLGAVGRDGVQRSMGLLEALSEADTVRRLELPVH
                     TMLPVVLRQVLLPVMIDALGAPRTRQEWGERFHRGHFSAEERDRLASYLGPRYGDRFRL
                     FDVERPFSQVAGLKALNGETKTAAQMVPSVASGNNVPLFSSVSEADELLLTPGDAALWL
                     LHTHCWDTASIKTGAVGDPQAKNGKTTGNPTGPLGQFGVVVPTGRTLYETLLLNTPILY
                     DGLEPGDRPQWAWDERPAGSGCTSPAGAAWSERPATGLLDLLTFQARRVRLIACESEQG
                     LRVHRVIVSAGDRLTRTPETEPHTAWQHTVKPKKGQPSTRPRRHASGRAAWQGLGTLLA
                     MALPMQSDGPYTSLLLRQVGDLQFGGVLSGQYPLEVETSGLEFGTQSAVVENAIGDDLP
                     LPVKALLAQDDWLREALLKCVGQADRVARALDGLNNDLRRASGGDPLPRDKGSRPSMQF
                     LHSLDGTMRRLLAGLRTVDADDEELLERAQLAWEQSVQIAADRQADLLLAAAPPRAVVG
                     RTVKIGDKEFVYRSGKAVGVFRSRLADILERAVAERRTRREEEAAV"
     misc_feature    23892..23907
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.6"
                     /tool="antismash"
ORIGIN
        1 tcccaggtga ccgtggacgg cgagacccgt ccgctcgccg acccgttcct ggtgatagcg
       61 accgccaacc cggtggagta cgagggcacg tactcgctgc ccgaggctca gctcgaccgg
      121 ttccaactgc gagtgcggat gggttacttg agcgcgccgg aggagctggc gatgctgcgg
      181 gcgcgggtcg accgggcggc tcccgaggcc gcgctcgaac ggctcgcggg accggaggac
      241 gtcgtggcgt ggcggtccgt cgtggagcgc gtggagatcg acgacgacct gctggagtac
      301 gccgtcgccc tggtcggcgc gacccgcggg cacccgcaga tcagcatcgg cgcctcgccg
      361 cgcggcggac tcgccctggt ccagctggcc cgcgcccgcg ccgtgctgga cggccgcgac
      421 tacgtcgtcc cggaggacgt caagagcctc gccgtgccgg cgctggccca ccgggtgtcg
      481 ctgcggccgg agttgtgggt gcgggagatg tccacggacg acgtgctgcg cgagatcgtc
      541 gacggtgtcg gtacaccgac gacgcggcgc accgcccccg taccgtcgtg accgcacccg
      601 agtccgcacc cgcccctggg cccgcgcggg cgaccggcgc cccggcacca tccgggactc
      661 ccgtgccacc cgggactccc gtgccacccg ccactccccc gcgacccgcc accgccgtac
      721 ccgtgccgcg gcagcctgcc cccgcggtgg tccgcgccct ggagggacgc acctcccccg
      781 tccagccgcc ctccccgccg cccgacgggc cgcgccccgg cgagcggacg ctgcggctgc
      841 tggccgtcgc cgcgatcgcg ctgtccgccg cactggtgac cggccatgcg tggctgttcg
      901 cgctcgcggc ggcgccgctg gtgctgctgg cgctcgccct gccgcgcgcg tacgcccgtc
      961 ggatcgagac gtcggcgacc gtcgagccgg cccgctgttt cgagggcgac acggtcaccc
     1021 tgcgtatcgc ggtggcccac gacggggacg ccgtccgcct cgaccccggc gccaccctgg
     1081 gcccgggcct cagcctcgac gaagtggtcg tcggctccgc ttcggtgacg ctgcgccaca
     1141 ccgcgctgca ctggggacgc tggtcgctgg gcccggtgga tctcgacgtg tacgacgccg
     1201 ggggcaccgt acgccgcacc gtgcgggtcg aggcggccga ggtgtcggtg ttcccgcacg
     1261 ccaccgaggc ccgcttcacg ccgatcccgg cgcggctgcc gcagcggctc ggcgagcacg
     1321 cctcgccgca gaccggcgag ggggtcgagg tcatcggggt ggcgccctgg gtgcccgggg
     1381 agcggcagcg gcgcatccac tggccgtcga cgacccggcg cgggagcatc cagctgcacc
     1441 ggttcgcggc cgaacgggcc gccgacgcgg tgatgctgat cgacgcgttc ggggacgtcg
     1501 tcgaccctgc gaccggggtg tcgtccctgg acgagacggt gcgggccgcc tccggactgg
     1561 cccgcgccta tctgcgcacc cacgaccggg tgggggtcgt ctcgaccggc ggcaccaccc
     1621 gctggctggc gccgggcacc ggggacgccg cgttctaccg catcgtcgag agcgtcctcg
     1681 acgtccgcaa ggaccggcgg ttcgacggac ccggcctcga acgggtgccg ccgcccgcgc
     1741 tgccggaggg agcgctcgtg tacgtgttca ctccgctcag cgacgcgcgc atcctggacg
     1801 tgctgcggga tctccggtcg cggggccgcc gcccggtcgt cgtggagatt cccagcggcg
     1861 acccgcaggt cgaggacggg gacgagaccg gcgagttggg gctgcggctg tggcgcgcgg
     1921 agcgggacgc gatgcgcttc acactgcggg acagcggggt gccggtggtg cggcacgccg
     1981 tgggtgagtc actggatctg gcgctggcgc cgctgctgtc ggggcgggtc ggcggaaggg
     2041 ggcgcgcggg atgacgacgg cgacggcgct ggacagacgg gtagggctgc gggagtacct
     2101 gggctactgg gtcggcaccc tgccggtgcg ggtgatcgcg gtggcggccg tcgtgatggc
     2161 gtggcggccg tggtcggcgg tgggtacggc aggagacgcg gtggtgcccg gctgcgtgat
     2221 cgcgttcgcg gtgtgggcgg cgcccgccct tgaccggcgg ccgtcgctgc ggtccgcccg
     2281 gtggtcctac cggctggagc accaccggac gaccctgctc gcggggagcg tcgtggtact
     2341 cgcggccttc ggcgaaccca cgtggtggga aggggcgtcg gtggtggtac tgctggtggc
     2401 ctacctgatg gcgagtgaga cctggccgtg gcgccggggg cgcgggacgg cccacgtgtg
     2461 ggtggaggcg gcggcggcct gtgccggggc gggtgtggtg gcggccgccg cggcggcacc
     2521 ggtgaccggg accggttcga gcctcgggcg ggtgatggcg gccggcgcgg tggcggccct
     2581 cgcggtagcc ggcggcgcgc tgctgcgcgc ccggtggcgg ggcgtcagat agccgagccg
     2641 acccggcgca gttgccccgg tccggcatcc cccgcgcacg aaagggcact gaattgtgcc
     2701 ctcaaagccc cggaatagcc gcttcacgaa aggggacgtg ccatgttccc gcatttcaca
     2761 cccgccccga gcgcagccgc aacccgacac cgggtttacg cgtcttcaga aggcgtagga
     2821 gcagttcgga gcacttctgt caccgaatgt ccatgaagcg tcgcaagacg ttcacaaacc
     2881 cccattgtcc ggtcaagtcg ttcatatgac ggctgataac gtgcccgatg ttccaccctg
     2941 ttccaccccc acagaaccaa gtacccgatc cttggatttc gctttatgac tggtacgcca
     3001 gacgaaaccc ccacgaacgc cttcaccccg ggcggacgcc gtcggcaccg caaggcaaga
     3061 gtgagccgca tcggcgggcg ccgggccctc gtactcgcga tggccgtgcc cgtggcctcc
     3121 gccaccctgg ccggcacgtc cgcgttcgcc gccgacaaca ccggcaccca ggcccagggc
     3181 gtctcggtcg acgacctcgc ggccgacgac gcacagctgg tcaagaacct cgaagagcgc
     3241 gtcgccgacg agcgcctggg caacgacgtc agcggcgtgg tgctcgacgc cgactcggac
     3301 accgccctct gggaccacaa cggcgccacc gcgctgatgc cggcctccaa cgccaagctc
     3361 gccacggcga ccaccgccct gacgctgctg ggcgcgaacc acgagttcac cacgaaggcc
     3421 gtgtacggcg agggcaccct caccctcgtc ggcggcggcg accgcaccct cacgagcgac
     3481 gacctcgccg agatggccaa gaccgccgcc gacggcctca aggccgcggg ccggtccgac
     3541 gtccaggtcc gcatcgacga cagcctgttc gccgacccga gcctcgccca gggctggaac
     3601 gagggctact accccaccga gatcacgccg gtccgctcgc tcgtcgtgga cggcgccgcc
     3661 gtcgacgaca cgtcgatcga cgccggcaag gtcttcgccg agaagctcgc cgagcagggc
     3721 atcaccgtcg acggcgaggt cagccgcgcg acgacgaagg actccgacgt accggtggcg
     3781 cagcacaagt cggcaccgct gtcggagatc gtcaagacga tgctcaagac gagcgacaac
     3841 aacatcgccg agaccctgct gcggatgtcc gccgtcgaac tcggcaagcc cggcaccttc
     3901 gagagcggca ccgcgctcgt ccgccaggtg ctcagctcgt acgggatctc cctcgacaac
     3961 ttcgagatgc acgacggcag cggcctctcc cgcgacgacc gcatcccggc cgccaccctc
     4021 gcgcagctcc tcgactcgat caccgagtcc cccgccctca gctcgatcct ggagggcctg
     4081 ccggtcgccg gtgaggccgg ggcgagcctc ggcccggagt ggggccgctt cgacgacccc
     4141 aactccgagt gcgccgtcgg caaggtccag gccaagaccg gcaccctcac cggcgccatc
     4201 gccctcagcg gtgtcacgaa gaccgaggac ggcgactggc ggatcttctc cttcatcgag
     4261 aacaactcga cggccgaccc gaccgacatc aaggacgcca tggacggcct cgccgccacc
     4321 gtcaacggct gctgggcctg accgcccccg caccgacgcc ccaccccgtc tgcgcgccgc
     4381 caaccggcgg cgcgcagacg cgcgagaagc tccggtgaac tgacccagcg accctgaagc
     4441 cgatccgcag gggaccatcc gcgggtgcgg ggagcagttc tgcgctccgc cgttaatgct
     4501 gctgcactgg ggaccatccc cgcgggtgca gggaggagac gacggagggg cgggcattgt
     4561 ggccgccttg ggaccatccc cgcgggtgcg gggagcagac tgtttgacct gcgagcttat
     4621 gaccgcagag gtgcgttttc agtgactttc gcagattccg gcaaataggg cacccacggt
     4681 atcggtccgt gcgtacgcag agttggtcga ccacagctcc ggcggattcc gactgccgca
     4741 cggctctccc tcacgcaggc tccggaagcg ggccgaggtg ttcggtcatg cgctcgcgga
     4801 gcagaaggta ctcctcgtag cggcggggca gtgggccggg cgggcgttcg acgacacggg
     4861 cggccgtgac ggtctctccg agctggaact gttcgcgtgt caggtcgagc tcgatgccgt
     4921 tgggcagctt gttccaccag tggaagttgc gctgagcacc gtcgaggtac acctcgccga
     4981 ccacgagatc gccgccgaag atgtcgttga cgatcaacgc cgtgatgtcg cagtggcccc
     5041 aggcggggtt gcccggcagc cactcgaccc gctcccggtc gtcgggtgaa caagtgtcgg
     5101 cagcccaact ggcacgcagg gctctgtcga tgtcgagcag gctccaaggg gtcacacacg
     5161 cagcatcgca gccgcctctg acatgcatgt cccagcacgc gcggcgcccg ccggttactc
     5221 agcccggcct gtcgcccgcc tcgtgggcaa ggcaggatcg gggcatgagg attctcgtca
     5281 tgggtggaac gtggttcctg ggcaaggcga ttgcggaaac cgccttggcg agggggtggg
     5341 acgtcaccac cttcaaccgc ggtcggtccg gcgtggacgt acccggtgtg gaggcggtgc
     5401 acggtgaccg tacggtccag gaggatctgt acaagctcgc gcagcgtggc ccctgggacg
     5461 ccgtcgtcga cacgtccagc tccgagctgc cgcctcgcga cgtccgtctc gccgccaccg
     5521 cgctggccgg agccgcacgc cgctgggtgc acctgtccac cgtctccgtc tacgagcgct
     5581 ggccgcacga accgctgacg gaggactccc ccctgctgcg gtgcccggcc gacgccgacg
     5641 agtcgttcgg gtacaccggg gaggacggca gccccacgaa gtacggcttc cagaaggccg
     5701 gcggggagcg ggccgtggtc gaagccttcg gtgacgaagc ggtcctcctg cggcccggcg
     5761 tcattctggg gcccggcgag tacgtgggca ggctgccctg gtggctggag cgcgcgaagc
     5821 gcggtggccg catgctcgcg cccgcacccg cggagcagcg gatccagccg gtggacgtcc
     5881 gggacgtcgc cggcttcgcc gtgcagcagg cagccggcac gggccgcgga gccttcaacg
     5941 tggcccatcc cgacgggatc tcgttcggcg gtttcctcac cgagtgtctg cgggtcaccg
     6001 ggggcgacgg gacgcccgtc tgggcggacc cgaccgtgct ggcggagcac cgtgtgaagc
     6061 agtggaccga gatgcccctg tggcgcaccc acgccggcgt ctggtcggtc gacgcccgac
     6121 gggcggtcga ggcgggcctt cgctgccggc cgatcgcgga cacggtgcgg gacacctgga
     6181 cgtggtggga ggggaacggg cgtcccgtgg accacccgcg acgggcggag cacgggatcg
     6241 ctgcggagaa ggagacacgg atcctcgcct ccctgtgagt caccgtggtc cggtccgccc
     6301 ccgtggttcc ggcggttccg gcggttccgg tcccgtctcg ggagttcctg taatcagaac
     6361 ccgatcgcca gaagggccac ggacgggccg agtcggtacg gcggggagac ccgggtgaac
     6421 tcctcgacct gttcccgcag ctgcgagggg agttgcgagc cgtggtagcg cgaccgtgac
     6481 aggtgcctcc cgatgcgggc cgtccggacg acgacgcccg tcttgcgctg ctcggccggc
     6541 acctcccaga tcggcgccag cgcctcggcg gcgccctcca cgttgtcgga cagcaggcgg
     6601 gcgtacgcca ggtcggcggc cgcgcccgcc aggacgtggg tggaccgttc gccccgcgcc
     6661 cgctgcccga ggagggcgat ggcacggccg gcctccgtct cggcctgctc cgggtccccc
     6721 atgagcagcg ccgtcgtgct gttcgacatg gccagccgct cctcggagaa gccgaactcg
     6781 ccacccacct cgtcgtgcag ctcgtcacgc gcctcctcgc cccggtcctc cgacagccgg
     6841 atcgtgcgac gtgcggacgt gacgtcgccg aggtgggcgt acgcgcgggc agcgatggcg
     6901 ttcaagcgcc gttgggcgac gtcgccgaga ccgccgtacg acagtgctcg ccgggacttc
     6961 gacagggcct cccccggctc tcccgagtgg taggcgatgt aggccagggt tccgtcggcg
     7021 taggcctgca ggggcgcgaa gcgcgtgctc tcggcgtaga cggccgtcgc cctggcgagg
     7081 gtgcgggcgc tggggaagta ccccaggtcg aatgcggcga ccgcgaggag tgcggccgtc
     7141 tggccgttga ggatcatcag ggtctgctgc tggaacggaa cctgcgtacg gtcccggtgc
     7201 cgttcgatgt cacggcgcag ggtgtcggcc gcttcgtagg cgtctgcggc cgacaggccg
     7261 tggtaccgcc gggcgaggct caccacctga tcgcggagtt cgtcgatggt gttgtcggag
     7321 atggacgccg cggcggtcgc gtcggcgccg tcgtgggctt cacgtgcggt catctgaact
     7381 cgctcttcca ggtcgaacgc gggtacctgg ggatcgtccg ccggtggcgc cgcgaaaagc
     7441 tgcgctgccg tgtacccggg ccacatggtc tccaggacgt ggcaagtctg cggcccgggc
     7501 aacccggtga gtttgccgcc ggtccagcgc cggaactgcg tctcaccgca ggtcgggttg
     7561 ttggtgctgt tcccgaagag gcggacgccg gtctcgttga acttcttgtc gaaccgtcgg
     7621 taggtgaggt tgtcccggtc gcacagcttg gcgagcaggg tcctcggtgc gcttctcaat
     7681 ccgcccccca agtctgcggc accgcgcctc tcggcctgcg gatggatccc ttcgcctgaa
     7741 ggagactccg gcttctcccc aagcggcaat acacctcgtg cagaagccac ttcaaagcta
     7801 tcccgacgcc acgagtgtca cccgtaagag ccgcaggaac catgcttccg gccatggcga
     7861 ggtcacgtgc cgcgggggaa cgatgatcac cggatttcgc cggacttgca tgtcagagca
     7921 cagtcgcccc ggtcggcgcc gcgacgccgt agtccgttcg ccgacctgcc cctcgaagga
     7981 actcgtctca tggctcctgc cgcgaccgtc gtgaaggctc cgccctctcc ccagccgacg
     8041 tccctgccct tcctccagcc gacgttcctg ccctcgccgt cctctccgct cgttccgcgc
     8101 cgggctcggc gcagggaaga cctccagcgc atcgtcgtac tgctccggcc cggcctgccg
     8161 gtcgacgggg ccttcgacgt cgtggtcgcg gttctcggcg acagagccgc accggctgag
     8221 gacgacgtac cggccctcgc cgagcggttc ctcggggccg gtcgggtaca gggccaccga
     8281 ccggccccgg tgcacgccgg ggccgggaag cagtccggcg aaccgggtct cggggcgtac
     8341 ctcgtcgcgc cggcgcacga ccccctgggg cagccgacgc gtacggacgg tacggcactg
     8401 ctcggtcgtc gcctccgccg cctcgctctc gccctcaccg ctcaggacct gccggagctc
     8461 ctgcagtccg gcgagggggg acgacgtcgt gcctgagccg acgccgccgc cgacggagcc
     8521 cgacgtcacc gtcatgcccc cggccgaggc ctacgacttc gactacttcc ggtgccgggt
     8581 ggatgccgga ctcctgtcgc ggagcatcgc cgtccgcgtg ttccgcatac cgctgctcgc
     8641 cgtgccggtg ggcggtagca ggcgcggagg ctggttcggc gccggcgacc tcgccggcgc
     8701 gctggccgtg cgtcaggtcc tggcggccct caacggcttc ccgtgcgcgc gcatcacgtg
     8761 gcagcgcatc ccgagttgtt cctacgcggt cgagtggggg gaccgtcctc cggccacgtg
     8821 gctcgacgac aacgagcgcc tggccttcta cggcctcacg tggcccgacc tcgcccccgg
     8881 ccgcccccac cgctcccgcg catccgctgt ctccagcggt tcctccaaca cggctcgtcc
     8941 gtacagctgc ggccctcact gaaaggagcc ggacgtgcac attcctggat caaggagtct
     9001 ccccaggccc cccagaactg ccgcggcgac gaccgcggta cggactcgtg gcacagcccc
     9061 gcccgccgcg gtggaagtga tgaacgagcg aatcacggtg gccggccctc gcagtgacgg
     9121 catgccccgc ccgcaggacc cggcgcgggt gggcgtcctc cgccggatcg ccgcagccag
     9181 actcaagcat cgcgggctcg acgcgatgac cggcgacgtc ctgctcatct cctccgaact
     9241 gctgacgaat gccttgctgc acagcggggc gacggagatc acgctgaatc tcaccgtcca
     9301 cgacggatac ctccgtatca ccgtcaccga cggcatgccg gggcgagcga aacgccggaa
     9361 ggccgacgac gaggccgaga cggggcgagg gctcggactc gtcgaagtcc tggccgagca
     9421 gagcggtggc acctggggca ccagcgagca cggcgcggcg acctggtgca gccttcgcgt
     9481 acccgccggg cagcggcggt gatgccgccg ttcaccgggc cgacgcacgg ccggccatgt
     9541 ccgcaccgct cctgatcctg ccgacctgcc cggacaaaag gtggtcggcc acgggcccgg
     9601 cgccactctc cccataccga gcagtgcccc aggtgcgggc tgcacccgca aggcgcggca
     9661 gtccgcacct ggggtcctga gatcccccgc ccctgttacg gggcggaccg acgaccaagg
     9721 agcaccagtg tcgattccga cccaccagcc tccccggcca accgcagtcg ttgccgaatc
     9781 cgtgccagtg ccggtgccgg tacccgccga ggagtgggag ctggacacca ccgtcacccg
     9841 ggctccggtc ccgatcgtcg aggcctgcgg caccggcgac ggctgcgcca agacctgcgc
     9901 ctcgtcctgc gcgtccagct gacacgcatg cccctgcggc ggtgcgggcg acctcccgca
     9961 ccgccgcacc gccgcaccac tcaccgagga gtcactgacg atggctcgtc ccaccttccg
    10021 caggcacggc gacgtcctgg tcctgcgtgc cgccgctatg ccggtgcggg cccgcccgga
    10081 cgactggccc gatgtcgagt cgctcgacgg ttgctgcgcg tggctcgccc gcgtgtggtg
    10141 cgacgactcc ttcgtcgttc cgctgcgcgc ggcgtcgccg cggctggccg gcttcgtcga
    10201 aaggatcctg gacggcgaca cggtcccgtt gaagcgggtc cgcagcgcga ccctgtccgt
    10261 cgccacctac ctcttgcggg catcgtcccg ggcgacaccg ttcggtctct tcgccggtgt
    10321 ggccctcgcc gacatcgggc cggtgtcggc gcgcctcggc accggccacc gggccgtggc
    10381 acgccccgac accctgtggg tggaccacgc gcgccgcgcg ctgcagcggc gcgcggacgt
    10441 gcttccgcac ctgaccctcc gggtcagcac cctgtccttc cggcgcggcg acaccgtctg
    10501 cacgccccgg ccgggcggac gcctggcgag cgcgccggtg acccgccccc tggccgtcct
    10561 cctggaggcg gcggccgcac cggccccggg ccgtctcctc cttgaggcgc tgtccgagca
    10621 ggcgggcggc acttccgagc aggccgtccg gctgctcgag caggctctgg aggacgggta
    10681 tctgaccagc gacctcgccg ccgacatgac ggtcgaggac cccgcccggc acatcgtgcg
    10741 caccctgcgg tcgtacgtgg agacgctcga gccggacacg gtccggatca tcgaccgtct
    10801 ggaggaaacg gggcaggccc tcgccctgca caaccggtcc ggccccgggg cggctcccgg
    10861 gctgcgcgac ctggccgaca agggcatgcg tgagctccag gcggcggact gccaaagcag
    10921 gatcagcctc gacctgtgcc tcgatgctca ggtctccgtg ccgcaccagg tcctggacga
    10981 ggtggaacgt gccgcgcaca cgctcgtacg cctgacccgc gcccaggggg aatcacccgc
    11041 gtgggccgcc taccagacgc acttctggga gcactacggc gccggggtcc tggtcccggt
    11101 ccgtgaagcc gccgacctcg ccgcgggact cggattcccc gccgactacc cgatgtcggt
    11161 gtggaaccag gccccgccca cagtgctccc gcgtgacgaa caactggcgg cacgtgccat
    11221 gcgggctgcc gtgaccggcg accgcgagat cgtcctgtcg gagcgggacg tcgacgctct
    11281 cgccggcgac ggaccggaga gaccgtcggc gccacacgtg gaggtcggtt tccggatccg
    11341 ggccgtcagc gaaaaagccg tgagcagcgg ggacttcacg ctcgacgtgc ggccggcgtg
    11401 gacggccggc gtcctgtccg gccgcttcac ctctctgctg ggacgccggc tgtcggacct
    11461 gtaccggaca ctgcccacca tgacccgagg agccctgccc gcgcagctct ccttcgtgcc
    11521 cgacttcccg cacgcccaga acgtctcccg cattcccgcc ctgctgcccc acgtcatccc
    11581 cgtgggcgag acccgtacag cgacgaacgg tgtcatcgac atcgacgacc tcgccgtact
    11641 ctccaccggc gagcaactgc acctggtcag cacgtcccgg cgccgcatcg tcgagccgca
    11701 cgtcctgcac ccactcgcgc tggagaagca agcccctgcc ctggtccggt tcctggccca
    11761 actggggcgc ggcttcgcga cggcatggac cgcgttcgac tggggaccgg tcgccgccgc
    11821 gctcccctgc ctgccgcggg tccgccatcg ccgtaccgtg ctggccccgg cacggtggag
    11881 actgtccgcc gcggacctgc cgtccggccc gtacggtacg gcctggcacg cggcactgga
    11941 cgcgtgggcg gccacctggc gatgccccgc ccggctgcac ctgctggacg acgaccgcac
    12001 catgctcctg gaccgcaccg aacccctcca cgcacgcctc atccaccagc accttcgccg
    12061 ccacccgcac gcggtgctca ccgaggccgt gcacgacgac gaactcggct ggctgggcca
    12121 cgcccacgag ttcaccgtcc cactcaccac gacccgcccg caggcaccgc acccggacct
    12181 gacccgcgcc cccgtggtga ccaaccgcga cctcgcccac cccggggacc ccggacagcg
    12241 gtggacccag gcgaaggtgt tcacccaccc caccgccatg gacgagatcc tgacgctgcg
    12301 gctgccccgc ctgctcgacg cgctcgggac ctcccaggcg tggttcgtgc gctacaggtc
    12361 cctgcaggag accgaccacc tccgaatccg cgtgcccacc ggcggaccgg gcagcctcga
    12421 ggccaccctg cgcgccctct ccgactggac gaagcgcctc gccgaagacc ggctcgcctc
    12481 ccggctcgtc ctggacggct accggcccga gaccggccgc tacggcaccg gagccgccat
    12541 ggaggcggcc gaggacgtgt tcgtcgccga cagcctcgtc gctcgctacg ctctcaccga
    12601 cattccaggc ctgaagaggg aaacggtctg cgccctgaac atgatcgacc tggcggaggg
    12661 tttcctcggc acgcaggagg gccgcgcctg gacggcccgt actccggcgc ccggcaagcc
    12721 ccgccccgag gtcacacggc agaccatcga caaagcggag accggccccc tcctccacac
    12781 gacgccccgc ctcgcccacg ccgtcgcccg acgacgggcc gcactcggcg cctaccggtc
    12841 gcacaccggc gcgagccgtc tggagcaggc cctcgaatcc ctcctccaca tgcaccacaa
    12901 ccggctgctc ggccccgacc gggacagcga agccgcctcc cgccacgccg cacgccaggc
    12961 ctgccggtcc ctggtgatga gggcgacccc gtgagccacg acgaccacga cgacctcggc
    13021 ggcggcctcg ccggaaacgc cctgtacgcg atggtgatcg cccgcgagga agacgactgg
    13081 acggtggccc acgccgccgc gagagccatc acctcccacc ccatcaccgc tcaccccgca
    13141 cacgccaacc tctaccgggg cgcgcccgcg gtcgcccacg tcctgcacac cgcgggacac
    13201 cgggcctacg cccgctccct cgccgcgctc gacgccgaga cggccgcgat cgccgccgac
    13261 cgcctggacg ccgcgcacca ccgcatggac agcggccgtc cgccgcgcct gcgggagtac
    13321 gacctgatca gcggcctcac tggactcggc gcctacctcc tccaccgcgg ccacgacgac
    13381 gtcctcgagt gcgtactgcg ctacctggta cggctgatca ccaggcccct caccgtcgac
    13441 gggcaccagg tccccggctg gtgggcagca accgacccgc gcgactccgc tggcaccgga
    13501 cggttcgcac acggccacgc gaacttcggg atcgcccacg gcgtcaccgg cccgctcgcc
    13561 ctcctcgccc tcgcccgccg cgccggccgc accgtcgacg gacacgacga cgccctggcc
    13621 gaaggcgtcg cacacctcac cgcatgggcg cagcccttgg acaacggcag caccggctgg
    13681 cccgaactcc tgcccctgga cacctaccgc agaggacccc agcccggagc cgcgcccggc
    13741 cgcccctcct ggtgctacgg cacccccggc atcgcccgcg ccctgcaact cgccgcgctc
    13801 gccctccacg acaacgcggc ccgccgcctc gcggaacaca ccatgctcca gaccctcacc
    13861 gacacccgac agaccaacca gatcaccgac gcatcgctct gccacggctg gtccggcctc
    13921 ctcctggcct ccacccggac cgcctccaac gcagctctcc ccgacctcac caccgcacta
    13981 tcggccctgc acacacacct gaagcccgat gcgacgcggc acaggacaac caaggacacc
    14041 ggactcctca ccggcacccc aggcatcctc ctcaccgcac acaccctcaa caccacctcc
    14101 cgccccgtct cccccgggtg ggagacatgc ctccttctca actgaaagcg aaacgacagt
    14161 gagccagacc cccacggccg accagctctg caaccggctc gtcgacgaca tcctcagcga
    14221 acgcgacctg ccctccgacg tggaacaagc catgcgcacc gtgccccggg acaccttcct
    14281 gccgggcatc gacctcaaga acgcgtacac ggaccaggcc gtcaccatca aggacaaccc
    14341 cggccaacca ctcccattgt cctgcgcatc ggtaccgtcc gtcgtcgcga tgatgctcgg
    14401 ccaactcacc gcccgccccg gcgacaacgt cctcgagatc ggcgccggca ccggctacaa
    14461 cgccgccctc ctggccgaac tcgtcggcgg cggcagggtc accaccgtcg acatcgactc
    14521 cgacgtcgcg ctgcacgccc ggaccaccct caacacggct ggctacgagc gcgtcacggt
    14581 catcgagcgc aacgggctgc tcggcgccca cgaacacgca ccatacgacc ggatcatcgc
    14641 caccgtcggc gtctgggaca tccccgccac ctggtgggac cagctcgcag acggcggccg
    14701 cctcgtactg cctctgcgct ggcgcggcca gacccgctcc gtcgccctta cccgacacgg
    14761 gaaccaactc gtctccgacg gcatggaact gtgcggcttc gtcccgatca tcggccagaa
    14821 cggtgaaaag acggcctccc tcaacgccgc cgacaccctc cgcctccact acgaccagga
    14881 ccagaccatc aaccccgacg ccctcaccca caccctgcag gcggacaagc ccgcccgcga
    14941 ggtcctttcc gcccagcgga tcggcggcga ggagtccttc gacggagtct ggctgcgcgc
    15001 caccgctcac gacgaccgcg tatgccgcct cgaaaccacc cccgaggcca tggagcaggc
    15061 cctgatccgc aggcccgcca caccggcccg cacccccgcc ctgatcgacg acgcctccct
    15121 cgcctacctg accgtgaccc gggaagacgc cgacccgcaa cgcccgttcc gactcggcgc
    15181 gaccgcatac gggccccgcg gcgaagaact ggcccgggac ctcgtcgccc acatcgacgc
    15241 gtggggctcc gaccgcctgg cagtaccacg cctgaccatc acgccctccg acaccgggga
    15301 cgccccaggc cacaccatca gcaagccgga aagccgaatc acgctcacct attaggccgg
    15361 tcgcgacggc gtcccgcgcg tgcgagggga acgccgtcca agtcggccac cgcgcaggga
    15421 cgatcgccac cggcacgcgc agtaatgccg cttgaccgcc tcgacctgta cgcccgccaa
    15481 gccttccccg ccggcgcggg gagcagctgg tgctggggcc tcccgatgtc cgtgccatcg
    15541 ggccatcccc gcgggcgcgg ggagcagact gtctgacttg ggaatctatg ggctcgggag
    15601 cgcgctttca gtgactttca ccggattcga caaaggggac atggacggca tgtgatgcaa
    15661 gtcgggctca ctttgcgcgt ctacgcgtgc tccgtgagca acgggcacgg gacaaggctc
    15721 actggacgct ggtgcgggct atagcctgca gttggccggt gtccaccgtt ccccccgtgc
    15781 cgtcgtgtgt cagctcgagg ccgtcgctgt tgctgtccgc ccgccagacg gcgccgcgcc
    15841 ggttctccca ctcgacgaag ctgccgggag cgccgtcgag cagccccagt tcccgcacga
    15901 gagtgtccag gggcgcgaag ccgcgggcgt cgcccttgct catgctctga gtgcgggtgt
    15961 tgtcgtagcg catcttgacg aacggcacct cggtgcggtc gagcttgttc ggctggagca
    16021 ttttacggaa cctgccccag gcctcctcct cgctctcccg gccggagatc tcactggcgt
    16081 aggcgggaaa aacggcgtac gtgacggcgg acagctcggg gttctccgtg gcgtggtaat
    16141 cgtgcacctc gggtgccgcc actcccaccg tgtcgaatgc cgtcccgtcg tgctggaagc
    16201 cgccgacggc caccagaggc cgcccctgct ccacgaacgt gccgtcatgg gcgcgcgtgt
    16261 gggcgagcag cgccgtgacg aggccctcgt cgtaggggcc gcgtacgttg acctgcaggt
    16321 tatgccgacc gtcgatggag agcgcagcgg tgaacgtgaa catcgggttc ggcgaccacc
    16381 gccacgcgga agccagaccg gaaacggaag cggcgccggg caggtcggac aggagggatc
    16441 cagggttcat gaggtggctc ctgtgctcgg gacggggctc tagctgcacg aggagagggt
    16501 ggggtcgaca tcctggcggt aggtggcgtc caggagcaca ccgccacgaa agttctcgct
    16561 tcccgctcat gggttccatg ttgtcggagt ggttgtagaa gtcgttccgg gtggcccggg
    16621 cgaaacagta gccccgctgg cgcggggacg actacaacga ccggctgttc accagctggt
    16681 acggggagct acccccgcag gcgcggggac gactccttac tgtcggcggt cccgctggac
    16741 gcgggggagc tacccccgca ggcgcgggga cgacacttct tgagctgtgg ttttgtcagg
    16801 tgatcatgcc gttttgcttt acctcgttcg tgggccgcca gggttgtccg ttctggcgtg
    16861 ggcgggccat gagggtcagg ccgtcgaagt cgacgggggt ccagcggtcg cggccggcgg
    16921 tgcgggccga ccagccctgt tcggtggctg ccggttcgat catgacggcc tggccgtcgt
    16981 ggatgcgttc ggcgaggacg gtccacagac ggtcgcggat gcgggggttg gggttgccga
    17041 cgtagacgcc ggcggccacc tcgacgaacc agcgggtgag gtgtccgcgg aggccgggtg
    17101 gggccgcgat gagtacgacc acggtcgttc cggcgctcac ggggccgcct ctgcggaggt
    17161 gggttcgggg atgatgtcga ggtggtgtgt ggcgctccag ttgcggccgc cgctgacgac
    17221 ggtgtcgccg tcgtcccaga gggcgccgag gtcctcgtcc ggcaggtcgc tgccgccggg
    17281 gacgaggagt tgcttgatgt cggcgacgat gcggggcagg agcttgccct gcacggcggc
    17341 gtcgcgcagg gcggtacgtg cgtcccgctc cgaggtgagg ccctgtgcgg cgaggtcgaa
    17401 ggcgagcggg atggtgaact cggccttgta gaggtcggcg atgtccagga cgaaggagag
    17461 ggcgttgccg gtgtggacga agccgagggc ggggctggcg cccagtccgg tgatcgcggc
    17521 gtgggagatg ccgtagaggg ccgagttggc ggcggagagg agccggttga cgtcgtcgcc
    17581 cgctgcgaag gcgtcgccgg gtttgtagtc gcgtttggtc cagggcaccc cggtccgctc
    17641 ggcgtgctgg gcgtagagct tgcggatgcg ggtgccttcg cggccgcgga gctgctggag
    17701 ggtcaggccg gtggtgtcct cgcccgggaa gcgcatgtcg tacatgcggc gggcgacccc
    17761 gacccgttcc ttggggcggg tgaccagcca ggcctggcgg agttggagct gggagccgcg
    17821 tgcggtgctg gtgccggtgg cgtagaggcg tacgccctgt tcgccgaccc agcacaccgc
    17881 cgtgccggag tcggcgagca gcgtgatggc ggggtgggtg acgcggctgc cggggccgat
    17941 gaggaggacg gcgagccagg cggccggaac gtggacggtg cgggccttgt tgaccaggac
    18001 gatggcgttg tcgtcccggt cgatgtggca acgctcggcg tagaggctgg agatgcggtc
    18061 ctcaagcctg tgcacgtcct gcggtccggt gcgccaccag ggttcagcca tggttcgcct
    18121 gggtggtgcg cagcggggcg agggtgagca gtccctggcc gtagcccttg gcggggccga
    18181 taccggcgag gagggtggtg cgcaatgcgt cggggtcggt tacgtgcaga cgtccttcga
    18241 atgtggcggt ggacagggtg acgcgcggtc cgtcggagtg tttgcggaag cggaggatgt
    18301 ctcggccgac gatggtcacc gcgggtcctg cggacaggtc ctggtccgtg ctgtgcaaac
    18361 ccggggccgg cggcgtgacg gtggcgtcgg ggatggtgaa gccgtggcgt tcgcagcggc
    18421 tgaggagcca gtcgagctgt tgggccgcgg tgcggtgggc gacgcgtgcg ccgcggggcc
    18481 tactgccgtt gtcggccgct tctttcaggc gggtggcctg ctgttcgctc ggcctgtcgg
    18541 ggcgggggac gttgcggacg gggttggcgg tgaggcggaa gccgaactcg cggccccgca
    18601 cgagacgttc gagaagaggt gtgtagtcgg cgatgagcgg ggcgcccccg tcggctccgg
    18661 gccagccggc gtcgtcgacg aggtgggccc aggaggggcg gctctcggtc aggacgagga
    18721 cgtccgcccg gtgcggggtg ctgttctcca ggcgccacag gacgcgttcg gtgacgggtt
    18781 gcgtggccag cccggagagg acggcggcgt gcaggcggtg ggggctggag agcagggaca
    18841 cggcggcgcg gcggcgcggg ttgagagcga tcttcgacag gtaggccatg tggtcaccag
    18901 cccaggaggg cgaacgggtc gtggtcgggc tgcccggcgg tctccgtgtc cgttgcgtcg
    18961 gaggcccggc cggtggggac ggtgacccag aggtgacgca cggcgcgtcg gccgaaccgg
    19021 gttccggtct tgaggtcgta ggtgtcgggt acgtcgacgg tgagttggtc gccggccggg
    19081 tcctcgatgg tggcttccag ggccacggtg gtggttcggg cctgtcggcg gcggtgggcg
    19141 ccggcctgcc acggcacgtc cgtgagggct tgctccagcg gggcgtcggc gtggagtccg
    19201 aggccgacgg gtccggtggg cgggcaggag cggcgaccga gggagagggg gtagtggggg
    19261 ttgcggacgg cttcgtccag gctctgcacc aaggctttcg ggccacgcag ggcggcgacg
    19321 aagacggcgt cctggagata gaagcgctgg gtgaccccgg tgtgcttggc gggagtggtc
    19381 ctcgtctgct gtcccttggt gttggtcttg gccgacagca gcggcaaccc tcggtagtcg
    19441 ctgtaggtgt ggtagtcccg cagcagggtg ccgggctggt ccacccggat accgaggcgc
    19501 aggtcgacca ggtcggtgag ggatgcctcg cggctgcggc cctcggcggc ggcgaggagg
    19561 ccgaggatgc cggacttcgt ggggcggggg cgtgtctcgc gccggttgta ttgggagggg
    19621 ccgccccagg actggagagg ggcggccagc cgcagcacga ggacggcgtg gtcggtgccg
    19681 gtcatcgggc gtctgcctcc gcggtcgctg cgggcgtgat cccgccgtcg gcgagccact
    19741 ggccgaccag ctcaccgacg gagtcgagca gggcgggaaa gggcatggag gagccgaaca
    19801 cctcggtgac cttgtcgcct tcggccgtgt aggtcgccag ggtccgcagc ggtgcgttgc
    19861 cccacgtctc accgaccgcc ctgagctcgt cggcgagtcg caccacggat tcggaggcca
    19921 gcccggtggc cccggtgacg ggctcctcgt aggcggagac caggttcacc ggctggtccg
    19981 tgcggagcgt cagcagtacc aggtggggca gggtgcggtg ggcgaaggcg ttctggtgcc
    20041 cggtcggcat ggaccgggtg aacgcgtcga cgaaccggac cgccgcgctg cgggtctcct
    20101 cggcgtcggt gaggttgtca cgcagctggt gcacaccgag gacggcgtaa cggtacagcg
    20161 tcgaggagtt gaactcgacg gtgccgatca tgccggcgcc gtggtcgtcg gtgttctcgt
    20221 cgtcgaccgc ggtgtagtag tcgaactcgg tgcgcacggc gtgggtggac agggcgtgcg
    20281 cgacctggac ggaggcatcc acgttcaggg cgggcaggtc cgcgaccatg cggccgaaga
    20341 gggcgacctc ggccgggtgc ccggtggaca ggctcttgac gacggagagc ttcttcactt
    20401 ccgccttgag gtcgtcgtcg ggcagggcgg cgagttcggc ggcccggccg tcgaggagcc
    20461 ggaccaggga gtcgagctga gtcttgccga agaacagcag gtaggcggac tggtcgtcct
    20521 tcttggccga tttggtgatg ccgagcggtt ccagcagggc ggccgccagg cgttcggcct
    20581 gctcagtgtt gaggccggca ccgtcctggt cggtgggacg agcgaggcgg tggacgagca
    20641 gggcggcgat gcgcttggtg cgggtggctc ggtcggcctc cggagtgtcc ttggcgtact
    20701 cggtacgggt ggcccgcttc cacgcctggg aggagacccg ggcgcggcgg gcgccgccgt
    20761 agacggcctg cttgggcgta ccggagtcgt cccggttcac gttggacggc ggcaggctct
    20821 gcaagatgtg gacttcgacg aacagggtgg ggcggctcat ggcgtgactc cttggcagtg
    20881 tgtgggcgcc gctccggaga gggcgcgcgg agaagagggg ctgggccggg cccccggtgc
    20941 tcgctcccgg tgcgggcccc ggctgatggt tcaggcggac gcggcgcggt ggaagtcgtg
    21001 gtcccactgc tggcggtagc cggtggcgtc gtccgggcgg cgggggtcgt cccaggtccg
    21061 cagagcggtg cgcagcaggt tgtagtcgag accgatgcca gctcggttga gcagcgggac
    21121 gagggagcgc aggtgcatgg cgagttcgtc ggtatcggcg gaggtgagca gcgtgccgaa
    21181 gcgccgctcc agcgccgcag tggcggcctt gccctcaccg tccgcggcgt tcctgtgggc
    21241 gagcaggtcg gcggccgtgc ccggactgtt gcccgcgatg tgcatccggc ggctttgtga
    21301 ctgctggtgg cgggcgaaga gggtgagcgc gatgtgctcg gccgccaggt cccgggtgag
    21361 ggaccccttg tcccgccact cggactccat ccgggtgcgg tggaacggcc acatcgcggc
    21421 gaccgtgccc ggttcccggc cggtgcccga gcgcaacgcg gccagttccg ctccggtctc
    21481 cccgctctcg ggatcgaacg tcccccagta cggcgtctgc tccgcgccgg tgtcgtccgg
    21541 gtcgccttcc tgagacggcg tgccgggatc ggtgtactgc aggccccagg accggagcac
    21601 ccggtcccgc tgcggactgt cccaccgggt cagctcgtgg aacaggcgcg tgtagtcgag
    21661 gccgatgccc gccctgcgca ggagcggcac gagccgctgt aggtgctgtg ccagctcctg
    21721 gaggtcctga gaggtcgcgg ctgcggtcag acgtcgctcg acggcgctgt ccgtcaacac
    21781 ctcgctgcgg cgcaggagca ggcacgcggt acccagtccg acacccggcc ggtggacggg
    21841 ctcggacgcg gcgtgctggt gcagcccgaa caaggtgagc gtgtggtgct ctgcgacgta
    21901 ttcctccggg agacggtcgg agccgtcgtc ccggaggaag acgcgatgga ccggcaacat
    21961 ggacgcgacg gtgccggcct cccggccgag gccctcgcgc agggcccgca ggccccgcgt
    22021 gacgtactcg gggaattccg ggcggcggcc ctcgctgctc gccgagtgcc agtccccggc
    22081 cgtctcctcc cagaagaaca acctgagccg gttcgcagcg gcccgggagg ccgaagtact
    22141 gcctctgctc gtcatactgc ggcctcctcc tcgcgccggg tgcggcgttc cgcgacggcg
    22201 cgctccagga tgtcggcgag cctggaccgg aagacgccga cggccttgcc gctgcggtag
    22261 acgaactcct tgtcgccaat cttcaccgtg cgccccacca cggccctcgg tggggccgcc
    22321 gcgagcagga ggtcagcctg gcggtcggcg gcgatctgca cggactgctc ccacgcgagc
    22381 tgggcgcgct ccagaagctc ctcgtcgtcc gcgtcgacgg tccgcagccc ggcaagcaga
    22441 cggcgcatcg tcccgtcgag ggagtgcagg aactgcatgg acggacggct gcccttgtcg
    22501 cggggcagcg ggtcgccgcc ggaggctcgc cgaaggtcgt tgttgagccc gtccagtgcc
    22561 cgggcgaccc ggtccgcctg cccgacgcac ttcagcaggg cctctcgcag ccagtcgtcc
    22621 tgggcgagca gggccttgac cggcaggggc aggtcgtcac cgatggcgtt ctcgaccacg
    22681 gcggactgtg tgccgaactc gagacccgag gtctcgacct cgagtggata ctgcccggac
    22741 agcaccccac cgaactgcag gtccccgacc tgacgcagca gcagtgaggt gtaggggccg
    22801 tcgctctgca tgggcagtgc catggccagg agagtcccca gcccctgcca cgcggcgcgg
    22861 cccgaggcgt gccggcgggg ccgggtgctc ggctgcccct tcttcggctt gacggtgtgc
    22921 tgccacgccg tgtgcggctc cgtctcgggt gtccgcgtca accggtcacc ggccgacacg
    22981 atcactcggt gcacccgcag cccctgctca ctctcgcagg cgatgagacg gacacggcgg
    23041 gcctgaaagg tcagcagatc cagcagcccg gtcgccggac gctcggacca tgccgccccg
    23101 gccggtgacg tgcagcccga accggcaggc cgctcgtccc acgcccactg cggccggtcc
    23161 ccgggctcca gcccgtcgta caggatcggc gtgttcagca gcagcgtctc gtacagggtc
    23221 cgcccggtgg gtacgacgac gccgaactga cctagcggcc cggtcggatt gccggtcgtc
    23281 tttccgttct tcgcctgcgg gtctcccacg gcaccggttt tgatcgacgc cgtgtcccag
    23341 cagtgcgtgt gcagcagcca cagcgcagcg tcccccggcg tcagcagcag ctcgtcggcc
    23401 tcgctgaccg aactgaacag gggcacgttg ttgccggacg ccacggacgg caccatctga
    23461 gcggccgtct tcgtctcccc gttcaacgcc ttcaggccgg cgacctgcga gaacgggcgc
    23521 tccacgtcga acagacggaa ccggtcgccg tacctgggcc ccaggtagga cgcgagacgg
    23581 tcccgttctt cggctgagaa gtggccccga tggaaccgct cgccccactc ctgccgggtg
    23641 cggggcgccc cgagggcgtc gatcatcaca ggcagcagga cctgccggag caccaccggc
    23701 agcatcgtgt gcaccggtag ttcgagacgc cggacggtgt cggcttccga cagcgcctcc
    23761 agcagtccca tggaccgctg aacgccgtca cgaccgacgg cgccgagcca tccgtcgtgt
    23821 acgaggtctc cctcgtcggc catggtggtt ccccctccat gtactgacgt ccctgcgcct
    23881 tcgctgggac ggtgaccggc aggtcggcaa ctctgctctc cccaggcgga gttgccgacc
    23941 ctgaccggtc gccaacagca tggcactgaa cgcttggtat ttcaaccgga tcgcgcatgc
    24001 tcgatcacgg agggcgacgg cctgcatgga tgcccatcgg ggacgggtac gctgcgcacg
    24061 gcttgtggag ccggagctct ccccgaacgg gggtgttccc gcttggtact tcgcgagcag
    24121 gcgaagccgt ccccgcatgg cgggg
//
