LOCUS       NZ_CP043317            21029 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Streptomyces olivaceus strain SCSIO T05 chromosome, complete genome.
ACCESSION   NZ_CP043317
VERSION     NZ_CP043317.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces olivaceus
  ORGANISM  Streptomyces olivaceus
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8458055)
  AUTHORS   Zhang,C., Ding,W., Qin,X. and Ju,J.
  TITLE     Genome Sequencing of Streptomyces olivaceus SCSIO T05 and Activated
            Production of Lobophorin CR4 via Metabolic Engineering and Genome
            Mining
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8458055)
  AUTHORS   Zhang,C., Ding,W., Qin,X. and Ju,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2019) Key Laboratory of Tropical Marine
            Bio-resources and Ecology, South China Sea Institute of Oceanology,
            Chinese Academy of Science, NO.164 Xingang Road, Guangzhou,
            Guangdong 510301, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 28-MAR-2017
            Assembly Method                   :: HGAP v. MAR-2017
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 8458055.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015244315.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 18:39:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,352
            CDSs (total)                      :: 7,265
            Genes (coding)                    :: 7,077
            CDSs (with protein)               :: 7,077
            Genes (RNA)                       :: 87
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 188
            CDSs (without protein)            :: 188
            Pseudo Genes (ambiguous residues) :: 0 of 188
            Pseudo Genes (frameshifted)       :: 106 of 188
            Pseudo Genes (incomplete)         :: 98 of 188
            Pseudo Genes (internal stop)      :: 7 of 188
            Pseudo Genes (multiple problems)  :: 23 of 188
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:52:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 523983
            Orig. end                         :: 545012
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP043317.1.
            Bacteria and source DNA available from South China Sea Institute of
            Oceanology, Chinese Academy of Science; 164 West Xingang Road,
            Guangzhou 510301, China.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21029
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="5"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21029
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21029
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11029](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11029
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(684..698)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.18"
                     /tool="antismash"
     gene            1962..2627
                     /db_xref="GeneID:69758849"
                     /locus_tag="FYC74_RS02160"
     CDS             1962..2627
                     /codon_start=1
                     /db_xref="GeneID:69758849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011027343.1"
                     /locus_tag="FYC74_RS02160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4232 domain-containing protein"
                     /protein_id="WP_194274488.1"
                     /transl_table=11
                     /translation="MANTSQPVRRTALLASGLAVLGLLSACGSENGTSGTPPPSQSARA
                     SDAAPSAGTGTATDPGTAAAAGTPSDTAGSASASARTDGRCHTSELRAAVGRLDPGAGQ
                     RNLPLVLTNTSERTCTVYGYPGAAFVDASGKQLGPDPERAPGSPETLTLTPGASAWAGL
                     SFSSPEISGARTATPAALLVTPPDERASLKVEWTAGAVPVGGNASSVSVTALEAGTGP"
     gene            complement(2671..3639)
                     /db_xref="GeneID:69758850"
                     /locus_tag="FYC74_RS02165"
     CDS             complement(2671..3639)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69758850"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978092.1"
                     /locus_tag="FYC74_RS02165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldo/keto reductase"
                     /protein_id="WP_194274489.1"
                     /transl_table=11
                     /translation="MQYVKLGSTGLDVSRICLGCMTYGVPGRGAHEWTLDEDAARPLIR
                     QALEAGVTFFDTANVYSDGTSEEIVGKALRDFARRDDFVLATKVHGRMRPGPNGAGLSR
                     KAIMTEIDHSLRRLGTDHVDLYQIHRYDPHTPVEETMEALHDLVKAGKVRYLGASSMYA
                     WQFSKAQYTAERHGWTKFVSMQNHYNLVYREEEREMLPLCADQGVGVLPWSPLARGRLT
                     RDWDTATGRSATDAFGSTLYPEGDRAVVEAVTRIAGERGVPRAQVALAWLLHQDTVTAP
                     IVGASKPGHIEDAVAAVELVLGEKEIEELESPYTPHPVAGH"
     gene            complement(3718..4362)
                     /db_xref="GeneID:69758851"
                     /locus_tag="FYC74_RS02170"
     CDS             complement(3718..4362)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69758851"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017944841.1"
                     /locus_tag="FYC74_RS02170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="flavoprotein"
                     /protein_id="WP_382499305.1"
                     /sec_met_domain="Flavoprotein (E-value: 3.1e-10, bitscore:
                     38.8, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEQAGNSRRAASGGPVPDGGPAGNREPARTGARAGDGDPGGSKG
                     DPFLYVVVCAAGVASGVGALIDAALRRDWEVGVFATPVAMDGFFDTADVEARTGRPIRS
                     AWRRPGEPRPFPAPDAVVVAPATFNTVNKWAAGLADTLAVATLCEACGLGVPVGVLPCV
                     SDALASHPAYRASLDRLRGMGVRFGDPYEGGAAGGDRRFHWERALDLLVRR"
     gene            complement(4410..4610)
                     /db_xref="GeneID:69758852"
                     /locus_tag="FYC74_RS02175"
     CDS             complement(4410..4610)
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69758852"
                     /gene_functions="other (smcogs) SMCOG1265: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011027347.1"
                     /locus_tag="FYC74_RS02175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ferredoxin"
                     /protein_id="WP_031031916.1"
                     /transl_table=11
                     /translation="MDIGIDKDVCIGAGQCALTAPDVFTQDDDGYSTLQAGREDGGGSP
                     LVREAARACPVGAITVSERVG"
     gene            complement(4635..5849)
                     /db_xref="GeneID:69758853"
                     /locus_tag="FYC74_RS02180"
     CDS             complement(4635..5849)
                     /EC_number="1.14.-.-"
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016712 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen, reduced flavin or flavoprotein as one
                     donor, and incorporation of one atom of oxygen [Evidence
                     IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69758853"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004978785.1"
                     /locus_tag="FYC74_RS02180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_194274490.1"
                     /sec_met_domain="p450 (E-value: 3e-26, bitscore: 90.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTTTDPDTTRPVAYPQDRTCPYHPPAAYDPLRTGPPLAPVTLF
                     DGRPAWLVTGHTLARRLLVDQRLSTDRTRDGFPLTSPRLTGIRSRKLALLGVDDPEHRA
                     QRKMVLPEFTLKRAAALRPRIQEIVDERLDAMIAAGPPADLVQAFALPVPSMVICALLG
                     VPYADHEFFEEQSRRLLRGPLPADVRDARDRLESYLGELIDGKRTSPGDGLLDDLIRDR
                     LEEGEIDREQLISFAVILLIAGHETTANMISLGTYTLLENPGRLAELREDPALLPGAVE
                     ELMRMLSIADSLLRTATEDMEVEGHTIRAGDGVVFSTSVINRDGTVYPEPDAIDWHRPA
                     RHHVAFGFGIHQCLGQNLARAELEIALRTLFERLPTLRLAVPAQEIPHKPGDTIQGMLE
                     LPVAW"
     gene            6236..6685
                     /db_xref="GeneID:69758854"
                     /locus_tag="FYC74_RS02185"
     CDS             6236..6685
                     /codon_start=1
                     /db_xref="GeneID:69758854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978086.1"
                     /locus_tag="FYC74_RS02185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nitroreductase family deazaflavin-dependent
                     oxidoreductase"
                     /protein_id="WP_194274491.1"
                     /transl_table=11
                     /translation="MPLEGEYEPSPTQWVRDQVELYEGSGGTEGTTHPDTGLPVIVLTS
                     RGARSGKIRKTPLMRVEHDGRYAAVASLGGAPKHPVWYFNVLAEPHVELQDGTRKQDMT
                     AREVTGAEKAEWWERAVAAYPPYADYQKKTGREIPVFVLEPADAG"
     gene            complement(6758..7678)
                     /db_xref="GeneID:69758855"
                     /locus_tag="FYC74_RS02190"
     CDS             complement(6758..7678)
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69758855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040579.1"
                     /locus_tag="FYC74_RS02190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_031031923.1"
                     /transl_table=11
                     /translation="MLVALAANLVIAVAKAVGGFFAGSPALLSEAAHSVADSMNEIFLL
                     AALRRSRRPADRRHPFGYGKERFFWSLLAAVGIFVMGGCFSFFQGVEALRSGAEEELSG
                     YVAGLIVLGVALLAEGASLLRALHQVRGQGGLATGLRDPALRTVVAEDGTAVLGVTLAM
                     IGMVLHMVTGQVVWEACASLAIGALLVYVAYRLGREARDQLIGEAADPEADGRIRELLR
                     AQPEIDSVEALFTMKTGLDSALVAARVDLVPGLDSEEVEEAAVRIKRSIAHTVPEAGQV
                     FLDVTDRPAREAAQSPAATGERGGA"
     gene            7874..8899
                     /db_xref="GeneID:69758856"
                     /locus_tag="FYC74_RS02195"
     CDS             7874..8899
                     /EC_number="1.8.5.-"
                     /GO_function="GO:0004364 - glutathione transferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69758856"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978084.1"
                     /locus_tag="FYC74_RS02195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glutathione S-transferase family protein"
                     /protein_id="WP_194274492.1"
                     /sec_met_domain="GST_C (E-value: 3.7e-07, bitscore: 29.0,
                     seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGDDATPGNSGYGRKAFKRSRSHFADRITADGRDGWPVEPGRYR
                     LVVSRACPWASRALVSRRLLGLEDALSLAVADPVQDDRSWRFSLDPDGRDPVLGIRFLS
                     EAYDRRETGYPGGVSVPAVVDVPSGKLVTNDYQQITLDLATEWAALHRPGAPDLYPEAL
                     RAEIDEVMAGVYEDVNNGVYRAGFATGQEEYEAACTGVFRRLEQLTPRLEGQRYLVGDT
                     ITEADIRLFTTLVRFDAVYHGHFKCNRWKLAENPVLWAYVRDLFQTPGFGDTVDFDHIK
                     RHYYQVHTGINPTGIVPLGPDLAGWLAPHHREELGGRPFGDGTPPGPVRAEEEVPARGR
                     P"
     gene            8997..9299
                     /db_xref="GeneID:69758857"
                     /locus_tag="FYC74_RS02200"
     CDS             8997..9299
                     /codon_start=1
                     /db_xref="GeneID:69758857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676628.1"
                     /locus_tag="FYC74_RS02200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4235 domain-containing protein"
                     /protein_id="WP_194274493.1"
                     /transl_table=11
                     /translation="MAKTKKKKLPLAYKPVGFALGWLGGTLAGLAFQKTWKLIRDEDDA
                     PDALDPDRGWGEILLAAAIQGAIFAAVRSAVDRTGAKAIERSTGTWPIPGKGGRD"
     gene            complement(9345..9740)
                     /db_xref="GeneID:69758858"
                     /locus_tag="FYC74_RS02205"
     CDS             complement(9345..9740)
                     /codon_start=1
                     /db_xref="GeneID:69758858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978082.1"
                     /locus_tag="FYC74_RS02205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VOC family protein"
                     /protein_id="WP_194274494.1"
                     /transl_table=11
                     /translation="MALVNAGVVVLDCAEPERLAEFYKGLLGAEETDVTANRIEIEGPR
                     GFRLAFRRDVNATPPSWPRPENSLQVHLDLVVADLDEAERAIVGLGGRPVEAKDAAGPH
                     EERGFSDPAGHSFTLRLAVAPTAPKQG"
     misc_feature    9797..9815
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.57"
                     /tool="antismash"
     gene            10001..11029
                     /db_xref="GeneID:69758859"
                     /locus_tag="FYC74_RS02210"
     CDS             10001..11029
                     /EC_number="4.2.3.169"
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69758859"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040594.1"
                     /locus_tag="FYC74_RS02210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="7-epi-alpha-eudesmol synthase"
                     /protein_id="WP_194274495.1"
                     /sec_met_domain="T1TS (E-value: 4.8e-72, bitscore: 242.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQDVRFDLPFDTPVSPHLAHARERHLRWVRERGLVRSAAGFEEYR
                     SWDLSEAAARTYPHASADDMVVLMNWFSLAFLFDDQFDAARPDRAERIAEVARELIATP
                     LRPAGTPPRVECPITLAWAEVWGHLSDGMSLTWKSRFAASWGRFLVAHCEEVDLAAHGR
                     AATLGIEEYAVFRRRTVGIHHSIDAGERSRGFEVPAAAMAHPLMERMRDLAADTIGFMN
                     DIHSFERERRRGDGHNLVAVLQRERGCSWQEAADEAYRMTTDCLDEYVALEARVPQMCD
                     ELGLDGDGRTRVRLGVEAIQHWINGNYEWALTTGRYAAAKDGPVATAEQAGRGSVDDLL
                     GV"
     gene            complement(11091..12338)
                     /db_xref="GeneID:69758860"
                     /locus_tag="FYC74_RS02215"
     CDS             complement(11091..12338)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:69758860"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019327716.1"
                     /locus_tag="FYC74_RS02215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_194274496.1"
                     /sec_met_domain="p450 (E-value: 1.2e-06, bitscore: 26.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDDQTPSAPTGGGCPVAHGEGAVRLYGPDAATDPHEIYARLRGE
                     HGAVAPVLLEDDVPAWLVLGYRENRRVLDNPLQFSRDSRIWRDFQDGRVAETAPLMQMV
                     GWRPDCVSQDGEPHRRLRGAVTDNLYAVAGRGIRRHITHFANKQIDAFADEGRADLVAD
                     FAEYLPMLVLTRVFGLAEREGRTLAESSNQVIKGGADALTHNERIMGILGELAERKRRE
                     PGSDFASGLIEHNSGLDEDEIVNHLRLVLITAHTTTSNLLARVLQLVLTDSARLSGLVS
                     GQLNMSAVVEEVMWNSPPLAVLPGRFATADLELGGCPVKEGDLLVLGLTAGNHDPEIRP
                     DTGVSVEGNASHLAFSAGPHECPGQNIGQAIIETAVDVLLHRLPGLRLAVPASELTSTA
                     STWESRLDSLPVEFAR"
     gene            complement(12335..12940)
                     /db_xref="GeneID:69758861"
                     /locus_tag="FYC74_RS02220"
     CDS             complement(12335..12940)
                     /codon_start=1
                     /db_xref="GeneID:69758861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156547.1"
                     /locus_tag="FYC74_RS02220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_031031937.1"
                     /transl_table=11
                     /translation="MDFKGFDRPGSSTAGDTRSVKVMIAGGFGTGKTTMVRAVSDIKPL
                     TTEETLTQASADVDPLIGVADKTQTTVSLDFGKIGLNETLMLYLFGTPGQERFWFLWNG
                     LFKGALGAVVLVDTRRLASSFRAIEEMERQKVPFVIALNVFPDSRDYPVDEIRDALDIA
                     PHTPVVAFDARDPTAGRDVLVTLIRHLKDRSAAALEPR"
     gene            complement(12921..13292)
                     /db_xref="GeneID:69758862"
                     /locus_tag="FYC74_RS02225"
     CDS             complement(12921..13292)
                     /codon_start=1
                     /db_xref="GeneID:69758862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995719.1"
                     /locus_tag="FYC74_RS02225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_031031940.1"
                     /transl_table=11
                     /translation="MSAPRRPTDPSGLERYYVLTGGRSGPGGSASTLDVATLVVARAAP
                     LPGMQHEHEEILRRCRDPLSVAELGAHLHLPFNILAVLLSDLLQAGSVEARDPIPALDA
                     GRGPDLALLEEVLSGLQRL"
     misc_feature    complement(13155..13157)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13289..13699)
                     /db_xref="GeneID:69758863"
                     /locus_tag="FYC74_RS02230"
     CDS             complement(13289..13699)
                     /codon_start=1
                     /db_xref="GeneID:69758863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057749.1"
                     /locus_tag="FYC74_RS02230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_031031941.1"
                     /transl_table=11
                     /translation="MTHQGTDVSWALRDLVESIQEIRFALVASSDGKAITSYGAEDPDD
                     VDRFAAVVAGLQALAQPVAEQFPQHAGQLRLAMIEVDGGHLFVVRAGMETYLGVLAREG
                     LDQGLLGHQMRDLARRMGELLGTTPRQEEHSG"
     gene            complement(13705..15468)
                     /db_xref="GeneID:69758864"
                     /locus_tag="FYC74_RS02235"
     CDS             complement(13705..15468)
                     /codon_start=1
                     /db_xref="GeneID:69758864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015576969.1"
                     /locus_tag="FYC74_RS02235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_194274497.1"
                     /transl_table=11
                     /translation="MELATPPPAARVPVAWHSWWLMPLGLGGGTVAATFMSSERITVAV
                     AGAAATVAGTVCVRLLLRTRAQLGRAENAHRSARSENSQQWQQHVAGLERKFSAERSDL
                     DAQLTEQAQTYEERLAEHTRAYEDRLAEQATSYEARFAERTEAWQEQLGHQLAAVSRLA
                     DEQLPDAMRRLRSGDAIDDILPTVEQCSKVGADLQAELRKVLRTALIGVEAEFDRSTSA
                     EQAVISVGNRIHVLTSKLRGRLHEMQGEHGRLPTVARGLMELDQAIGPADCLAASIGVL
                     GGSDRPGRQWQEPQRLLSVMRGGIGRIKDFHRVQLRHLPELGVDGGLVDHLTLIFAHLL
                     DNAARYSPPTEPVVVSGKEVPNGVGIEIQDSGKGLSDEKKREAEHALAGTSPGAGLGGI
                     SEDANIGLRVVGALARRYGIRVTFADSPWLGTSVVVVVPHKYFSPLPSAAAPATVPDTA
                     QAATAPAADLVPPALVEAAAAPAPAVESTRAADPAPAADTAVETTPGGLPRRRSRRAEP
                     AAASGGAAPAAQQPGSEAADRAQASAVPPDASFTGLAAFATAGRDPGAGVGTSESTTGG
                     ASTEHRTEESD"
     misc_feature    complement(15619..15628)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.18"
                     /tool="antismash"
     misc_feature    complement(15620..15634)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.06"
                     /tool="antismash"
     gene            15870..16811
                     /db_xref="GeneID:69758865"
                     /locus_tag="FYC74_RS02240"
     CDS             15870..16811
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (21-310). E-value: 3.8e-56.
                     Score: 182.4. Matches aSDomain:
                     nrpspksdomains_FYC74_RS02240_PKS_ER.1"
                     /codon_start=1
                     /db_xref="GeneID:69758865"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978080.1"
                     /locus_tag="FYC74_RS02240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_194274498.1"
                     /sec_met_domain="ADH_N (E-value: 1.2e-09, bitscore: 36.8,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.5e-18, bitscore:
                     65.8, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTMRAVSQDVLGGPEVLKEVRVERPVPRPNEVLVRVRAAGVNPT
                     DWKHRADGGFLGEPPFVLGWDVSGTVESVGIGVAAFRPGDEVFGMLSYPFGHGSHAEYV
                     TAPARTFTHLPAGTDHVRAGALPLVSLTAWQALVERADLQPGQRVLIHAAAGGVGHVAV
                     QIAKARGAHVIGTASAGKHAFLRSLGADEAVDYRETDFTEAVRDIDVVLDTIGGDTSLR
                     SLRVLRPGGVVVSILPVGSGEFFEEAGRLGVRAVRMLVDADRADMREIARLVEAGKLEP
                     TIAKTFPLAEAAGAHALGETGRTTGKIVLVVD"
     aSDomain        15933..16799
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FYC74_RS02240_PKS_ER.1"
                     /evalue="3.80E-56"
                     /label="FYC74_RS02240_PKS_ER.1"
                     /locus_tag="FYC74_RS02240"
                     /protein_end="310"
                     /protein_start="21"
                     /score="182.4"
                     /tool="antismash"
                     /translation="RVERPVPRPNEVLVRVRAAGVNPTDWKHRADGGFLGEPPFVLGWD
                     VSGTVESVGIGVAAFRPGDEVFGMLSYPFGHGSHAEYVTAPARTFTHLPAGTDHVRAGA
                     LPLVSLTAWQALVERADLQPGQRVLIHAAAGGVGHVAVQIAKARGAHVIGTASAGKHAF
                     LRSLGADEAVDYRETDFTEAVRDIDVVLDTIGGDTSLRSLRVLRPGGVVVSILPVGSGE
                     FFEEAGRLGVRAVRMLVDADRADMREIARLVEAGKLEPTIAKTFPLAEAAGAHALGETG
                     RTTGKIVL"
     CDS_motif       16305..16367
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FYC74_RS02240_0001"
                     /evalue="1.70E-08"
                     /label="PKSI-ER_m5"
                     /locus_tag="FYC74_RS02240"
                     /protein_end="166"
                     /protein_start="145"
                     /score="26.8"
                     /tool="antismash"
                     /translation="GQRVLIHAAAGGVGHVAVQIA"
     misc_feature    complement(16888..16902)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.5"
                     /tool="antismash"
     gene            16966..17352
                     /db_xref="GeneID:69758866"
                     /locus_tag="FYC74_RS02245"
     CDS             16966..17352
                     /codon_start=1
                     /db_xref="GeneID:69758866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978079.1"
                     /locus_tag="FYC74_RS02245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="anti-sigma factor antagonist"
                     /protein_id="WP_194279297.1"
                     /transl_table=11
                     /translation="MRQESPSPTRHLRVRHERGHAVLEFRGEIDIASATEIAPHLDRET
                     RRPGARVVLDLGGIEFFDCSGLRLLARARNQVLAGGGEVHLVCSHPLTLRMLRITGLTR
                     LLPPRPTLQEVLGPALPTARRTGC"
     gene            17621..18304
                     /db_xref="GeneID:69758867"
                     /locus_tag="FYC74_RS02250"
     CDS             17621..18304
                     /codon_start=1
                     /db_xref="GeneID:69758867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007389369.1"
                     /locus_tag="FYC74_RS02250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4230 domain-containing protein"
                     /protein_id="WP_194274499.1"
                     /transl_table=11
                     /translation="MTTPVKKPTSDNRKPAPRMPGWAKALTAVVLVLAVLFAGLRLSVL
                     PGLKDLFGSETQDRSGPALLKSIQDMSRYDAASGNFQVVVDLEKDTKFLPDAIRGTRTL
                     YVGAGTVDAYVDLGKLGEDDVQVDGDRTSATLRLPHAALGEPALDPDRSYAVSKQRGLL
                     DRLGDLFSDNPNGEQAVQKLASRHIGEAAKDSELKTRAESNTTAMLQGLLRSLGFEDVR
                     VVYKG"
     gene            18438..18977
                     /db_xref="GeneID:69758868"
                     /locus_tag="FYC74_RS02255"
     CDS             18438..18977
                     /codon_start=1
                     /db_xref="GeneID:69758868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040640.1"
                     /locus_tag="FYC74_RS02255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VanZ family protein"
                     /protein_id="WP_194274500.1"
                     /transl_table=11
                     /translation="MARAVSGLRLWPRPRAAETRKADPPERHALALPLRLLATACAFVF
                     MVAFAVVLARLTLHPSPASEALTHTNMRPGSSLRAYLDQPALRDAVKQIGGNILLGVPF
                     GVLVPVVAPRTRGVLRVLLLTAVVMLLVEFAQGALVTGRAFDVDDVILNTSGALIGYLL
                     LGRRMSRTVHARKARG"
     misc_feature    complement(18988..19003)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.73"
                     /tool="antismash"
     misc_feature    complement(19024..19038)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.82"
                     /tool="antismash"
     misc_feature    19025..19038
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.32"
                     /tool="antismash"
     misc_feature    19026..19039
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.04"
                     /tool="antismash"
     misc_feature    complement(19027..19040)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.12"
                     /tool="antismash"
     misc_feature    19028..19041
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.1"
                     /tool="antismash"
     gene            19111..20367
                     /db_xref="GeneID:69758869"
                     /locus_tag="FYC74_RS02260"
     CDS             19111..20367
                     /EC_number="3.2.1.-"
                     /codon_start=1
                     /db_xref="GeneID:69758869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016325253.1"
                     /locus_tag="FYC74_RS02260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycoside hydrolase family 16 protein"
                     /protein_id="WP_194274501.1"
                     /transl_table=11
                     /translation="MVRPRLLRRCLLAATLSAGLAASLVTGPAQAEPEGPATAGTAGAS
                     AAAVVFSDTFDGPAGAAVDSSKWQIETGDNVNNHERQYYTSGNKNAALDGQGHLVVTAR
                     KENPANYQCWYGTCQYTSARLNTSGKFTAQYGHVEARMKVPRGQGMWPAFWMLGTPVNW
                     PDSGEIDIMENVGFEPSTVHGTLHGPGYSGSGGIGAGYTLPGGQSFADAFHTFAVDWAP
                     DSVTWSVDGNVYQRRTPADLGGRQWVFNRPYFLILNLAVGGYWPGDPDGSTVFPQTLVV
                     DHVSVTTGDSPAGGAIRGLAGKCVDVAAADTANGTPVQLYDCNGTTAQQWTVGSDGTIR
                     ALGKCLDVNAGGTADGTVVQLWDCNGSAAQQWVVTAARDIVNPQADKCLDVTGNNSANG
                     TRLQIWTCAGTANQKWTVG"
     gene            complement(20398..20634)
                     /db_xref="GeneID:69758870"
                     /locus_tag="FYC74_RS02265"
     CDS             complement(20398..20634)
                     /codon_start=1
                     /db_xref="GeneID:69758870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004979480.1"
                     /locus_tag="FYC74_RS02265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_194274502.1"
                     /transl_table=11
                     /translation="MTEIDSPHIGSPRILVLGVQPGTPPFRIVEIDGQVVGAARDVTDV
                     LEAAAAFGITVHDLDDPDVVRWVGGDKFTWTRR"
ORIGIN
        1 ccggcggcag gacctgcgca gtcatctgag ggccgagggc gaggagcgcg cccacgcctg
       61 ggtcgccctg atggcgccgc tcaccgacgc cgacgggctg gtgcgcggcg tgtgcgtgag
      121 cgcccacgac ttcaccgagc agcacctcgc ccgggagcgg ctgcaactgg tcaacgaggc
      181 cagcgtgcgg gtcggcagca ccctcgacgt caaccgcacc gccgaggaac tggcggacgt
      241 gtgcgtgccc gcgctcgccg acttcgtgag cgtcgacctg ctggacccgc gggacaacgg
      301 cggtgagccc gacaccgtgg tcgaaccacc ggtcggcctg cgccggacgg cccaccggac
      361 gcacctgccc gaccactcgg ccggctcggc ccactcgtcg acgtgtccgc ctgcggccgc
      421 cgagaccggc cggctggact tctacccggc gggctcgccc caggccgagt gcctgctctc
      481 cggccgggcg atcgtggccg ccgaggcgca cggcgacctg gagcgctgga tgggctggga
      541 cccggcgcgc ctgcggcagg tgcgggagca cggcgtccac tccgtgatgt cggtaccgct
      601 ccaggcccgc ggcaccactc tcggcgtggc ggtcttcatc cggttccggc gcctgcaccc
      661 gttcacgcac gacgacgtcc tgctggccga ggaggtcagc gcccgcgccg ccgtctgcat
      721 cgacaacgcc cgccgctact cgcgcgagcg cgaggccacc ctgaccctgc aacgcagcct
      781 gctgccccgg tggctgccgc ccaccgcagc ggtgcaggcg gcctcccgct accttccggc
      841 ggcccgctcg ggcgtcggcg gcgactggtt cgacgtcatc ccgctgtccg ggatgcgggt
      901 cgccatggtc gtcggggacg tcgtcgggca cggcatcgcg gcgtcggcca ccatggggcg
      961 gctgcgcacc gccgtacgca ccctcgccga catcgacctg acgcccgagg agctgctcac
     1021 ccacctcgac gacctggtcg tccgcctctc cgaggagtcc ggcgacgacc gggccggcga
     1081 ggtcggcgcc acctgcctgt acgcggtgta cgacccggtc tcgcggcact gcgccatggc
     1141 cagggccggg cacccggcgc ccgtcctggt gccgccggac ggcccggcgc ggcaggtcga
     1201 gctgccctcg gggccaccgc tgggcgtggg cgggctgccc ttcgagtcgg ccgagctgga
     1261 gttgcgcgag ggcagcgtcc tggcgctcta caccgacgga ctggtcgaga gccgggaccg
     1321 ggaccccgac gccggcctgg cactgctgtg cgaggcgctg gccgcgcccg gcgactcgct
     1381 ggacgccgcc tgcgaccggg tgctgcacag cctgctcccg gcgggcagcg ccggcgacga
     1441 cgtggccctg ctgctggccc gcacccgggg gctgcccacc gggcaggtgg ccacctggga
     1501 catcccggcc gacccgtcgc tggtcgcccc ggtgcgcaag caggtgctcg accagctcgc
     1561 cgtctggggt ctgacggatg cctccttcac cgtcgagctg gtggtgagcg agctggtcac
     1621 caacgcgatc cggtacggct ccccgcccat ccggctgcgg ctcatccacg acgcgaccac
     1681 gctgatctgc gaggtctccg acagcagtca caccgcgccc cacctgcgcc gggcccgcac
     1741 ctgggacgag ggcgggcgcg gtctgctgct ggtggcccag ctcacccagc gctggggcag
     1801 caggcacacg acggagggca agacgatctg ggccgagctg ggcctggtcg aggaggagtg
     1861 agccgtcgcc gtttcccggg ccgtgcgacg ggacacccgg agtacagggc gcacggcgcc
     1921 acggcaggcg tacgcggaaa ccacgggagt gtgaggaagc catggccaac acgtcccagc
     1981 cggtgcgccg gacggccctg ctcgcgagcg gactcgcggt cctcggcctg ctgagcgcct
     2041 gcggcagcga gaacggcacg tccggcacgc ccccgccctc gcagtccgcc cgcgcctcgg
     2101 acgcggcccc gagcgcgggc accggcaccg ccaccgaccc cggcaccgcg gcggcggccg
     2161 gcacgcccag cgacaccgcc gggtccgcgt cggcctccgc ccgcaccgac ggccgctgcc
     2221 acacctccga gttgcgggcc gccgtcggcc ggctcgaccc gggcgccgga cagcggaacc
     2281 tcccgctcgt cctgaccaac acctccgagc gcacgtgcac ggtgtacggc tatccgggcg
     2341 ccgccttcgt ggacgcgtcc ggcaagcagc tcggcccgga cccggagcgc gcgcccggct
     2401 cgcccgagac cctcacgctg acgcccggcg cgagcgcgtg ggccgggctg tcgttctcca
     2461 gccccgagat cagcggcgcc cgcaccgcga ccccggccgc gctgctggtc acgccgccgg
     2521 acgagcgggc ctccctcaag gtggagtgga cggccggtgc ggtcccggtg ggcggcaacg
     2581 cgtcgtcggt gtccgtcacc gccctggagg cggggaccgg cccctgaccc accggcaccg
     2641 gcagggtgtc cgcctcgcac ggcccgaccg tcagtgaccg gcgaccgggt gcggcgtgta
     2701 ggggctctcc agttcctcga tctccttctc gccgaggacc agttcgaccg cggccacggc
     2761 gtcctcgatg tgccccggct tcgacgcgcc cacgatcggg gcggtcaccg tgtcctggtg
     2821 caacagccag gcgagggcca cctgggcgcg cggcacgccg cgctcgccgg cgatgcgggt
     2881 caccgcctcg accacggcgc ggtcgccctc cgggtagagg gtgctgccga acgcgtccgt
     2941 ggcgctgcgc ccggtggcgg tgtcccagtc gcgggtgagc cggccgcggg cgagcgggct
     3001 ccagggcagt actcccacgc cctggtccgc gcacaggggc agcatctcgc gctcctcctc
     3061 gcggtacacg aggttgtagt ggttctgcat ggacacgaac ttcgtccagc cgtgccgctc
     3121 ggccgtgtac tgggccttgg agaactgcca cgcgtacatc gaactggccc cgaggtaacg
     3181 gaccttgccc gccttcacca ggtcgtgcag ggcctccatc gtctcctcga ccggcgtgtg
     3241 cgggtcgtag cggtggatct ggtacaggtc cacgtggtcg gtgcccagcc gccggaggct
     3301 gtggtcgatc tcggtcatga tcgccttgcg ggacagcccg gctccgttgg gcccgggccg
     3361 catccggccg tgcaccttgg tcgccagcac gaagtcgtcg cggcgggcga agtcccgcag
     3421 cgccttgccg acgatctcct cgctggtgcc gtcggagtag acgttggccg tgtcgaagaa
     3481 ggtgaccccg gcctccagcg cctgccggat cagcggacgc gcggcgtcct cgtcgagggt
     3541 ccactcgtgg gcgccgcggc cggggacgcc gtaggtcatg cagcccaggc agattcgcga
     3601 cacgtcgagg cccgtcgaac cgagcttcac gtactgcatc gttgctgctc ctgtgttctc
     3661 gggatcatcg gtacagggcg agcgtacgac ttcgcgcgca ctccaacgcc accccggtca
     3721 gcgccgtacg agcaggtcca gggcgcgctc ccagtggaac cgccggtcgc cgcccgccgc
     3781 cccgccctcg tacgggtcgc cgaagcgcac acccatcccg cgcagccggt ccaggctcgc
     3841 ccggtaggcg gggtgcgagg ccagcgcgtc ggagacgcac ggcaggacac cgacgggaac
     3901 gccgaggccg caggcctcgc acagggtggc cacggcgagg gtgtcggcca ggcccgcggc
     3961 ccacttgttg acggtgttga aggtggcggg ggcgaccacg acggcgtccg gggccgggaa
     4021 ggggcgcggc tcgccggggc gtcgccacgc cgagcggatg gggcgcccgg tgcgggcctc
     4081 cacgtcggcg gtgtcgaaga agccgtccat ggcgaccggg gtcgcgaaga cgcccacctc
     4141 ccagtcgcgt cgcagggcgg cgtcgatcag tgcgccgacg ccggacgcca cgccggccgc
     4201 gcagacgacg acgtagagga aggggtcgcc cttgcttccg cccgggtcac cgtcccccgc
     4261 ccgtgcgccg gttcgcgccg gttcgcggtt tcccgccggt ccgccgtccg gcaccggtcc
     4321 gccactcgcg gcccgtcgac tgttcccggc ctgttcgctc accccggaac cctaagggac
     4381 gggccccggg ggagccgaac gccccggggt cagcccaccc gctccgacac ggtgatggcg
     4441 ccgaccgggc acgcccgggc cgcctcccgg acgagggggc tgccgccgcc gtcctcgcgg
     4501 ccggcctgca gggtgctgta gccgtcgtcg tcctgggtga acacgtccgg ggcggtcagt
     4561 gcgcactgac cggcgccgat gcagacgtcc ttgtcgatac cgatgtccat gcccgttgcc
     4621 atgtccggac cctcctacca ggccacgggg agttccagca tcccctggat cgtgtcgccg
     4681 ggtttgtggg ggatctcctg ggcgggtacg gccaggcgca gcgtgggcag cctctcgaag
     4741 agggtgcgca gggcgatctc cagttcggcg cgggcgaggt tctggcccag gcactggtgg
     4801 atgccaaagc cgaaggcgac gtggtgacgg gccgggcggt gccagtcgat ggcgtccggc
     4861 tccgggtaga cggtcccgtc gcggttgatg acggaggtcg agaagaccac cccgtcgccg
     4921 gcccggatgg tgtgcccttc cacctccatg tcctcggtgg ccgtccgcag caggctgtcc
     4981 gcgatcgaca gcatgcgcat cagctcctcg accgcgccgg gcagcagcgc ggggtcctcg
     5041 cgcagctcgg ccaggcgccc ggggttctcc aggagcgtgt aggtgcccag cgagatcatg
     5101 ttggcggtgg tctcgtggcc ggcgatcagc aggatcacgg cgaaggagat gagctgctcg
     5161 cggtcgatct cgccctcctc cagccggtcc cggatgaggt cgtcgagcag gccgtcgccg
     5221 ggcgaggtcc gcttgccgtc gatcagctcc cccagatagg actcgagtcg gtcccgggcg
     5281 tcgcgcacgt cggccggcag cgggccgcgc agcagccgcc gggactgctc ctcgaagaac
     5341 tcgtggtcgg cgtaggggac tccgagcagc gcgcagatca ccatggaggg caccggcagc
     5401 gcgaaggcct gcaccaggtc ggcgggcggg cctgccgcga tcatcgcgtc gaggcgctcg
     5461 tcgacgatct cctggatgcg cgggcgcagg gcggcggcgc gtttgagggt gaactcggga
     5521 agcaccatct tgcgctgggc gcggtgttcc gggtcgtcga caccgagcag ggccagcttg
     5581 cggctgcgta tcccggtcag ccggggcgag gtgaggggga agccgtcgcg ggtgcggtcg
     5641 gtcgacagcc gctggtcgac gaggagccgg cgggcgaggg tgtggccggt cacgagccag
     5701 gcggggcggc cgtcgaacag ggtgacgggg gcgagcggcg ggccggtgcg cagcgggtcg
     5761 taggcggcgg gcgggtggta ggggcaggtc ctgtcctgcg ggtaggcgac gggtcgcgtc
     5821 gtgtccgggt cagtcgtcgt gtccgtcatg gaagacctcg cagacgaaat cggtgcctcg
     5881 tgccgagcta aattagatgc cctgggcacc tatgtggcca cgtcaagttc ggccagaccg
     5941 gtggcatggg cagagtggcc ggggaccgcc gggtgaggga cgcccggagc cttccccgcg
     6001 gccgggacgg acggtgggcg tggcctgatc gcgtcgttcg gcgggaccgc ccggcccccg
     6061 ggtgcggccg ggattgtccc gttccggccg tcgaacggac gcgcccgctc cggatgtccg
     6121 cgcggtgttc gggggtacag ggcaggatgc aggatggacg gacgggttcc gcaccggccc
     6181 ggtggtccgc accggccggg cggtccgaca acgcgacgat gggacggatg cacagatgcc
     6241 tcttgagggc gagtacgaac ccagcccgac gcagtgggtc cgggatcagg tcgagctgta
     6301 cgagggctcg ggcggcaccg agggcaccac tcacccggac acgggcctgc ccgtgatcgt
     6361 gctgaccagc cggggtgcgc gcagcggcaa gatccgcaag acgccgctga tgcgggtcga
     6421 gcacgacggc cggtacgccg cggtcgcctc cctgggcggg gcgcccaagc acccggtctg
     6481 gtacttcaac gtgctggccg agccgcacgt ggagctccag gacggtacgc ggaagcagga
     6541 catgacggcc cgtgaggtca ccggcgcgga gaaggccgag tggtgggagc gcgcggtcgc
     6601 ggcgtatccg ccgtacgcgg actaccagaa gaagacgggc cgggagattc ccgtcttcgt
     6661 cctggagccg gccgacgccg gctgatccgg cgcacgggac ttctcccgga cccgcggacc
     6721 cgacggcatg gaccgtcgcg tgccgggcac acgacgctca ggccccgccg cgctcccccg
     6781 tcgcggcggg gctttgcgcc gcctcccgcg cgggacggtc ggtgacgtcg aggaagacct
     6841 gcccggcctc gggcacggtg tgggcgatcg accgcttgat gcgcaccgcg gcctcctcca
     6901 cctcctcgct gtccaggccc ggcaccaggt cgacgcgagc ggccaccaga gcggagtcga
     6961 ggccggtctt catggtgaac agcgcctcga cgctgtcgat ctccggctgc gcccgcagca
     7021 gctcgcggat ccgcccgtcg gcctcggggt cggcggcctc gccgatcagc tggtcgcggg
     7081 cctcgcggcc caggcggtag gccacgtaca cgagcagcgc gccgatggcg agcgaggcgc
     7141 aggcctccca caccacctgc ccggtgacca tgtgcaggac cataccgatc atggcgaggg
     7201 tgacgccgag cacggccgtg ccgtcctcgg cgaccaccgt gcgcagcgcc gggtcgcgca
     7261 gcccggtggc gagaccgccc tgcccgcgta cctggtgcag ggcgcgcagc agggaggcgc
     7321 cctcggcgag cagggcgaca ccgagcacga tcagtccggc gacgtagccg ctcagttcct
     7381 cctcggcgcc ggagcgcagg gcctcgacgc cctggaagaa ggagaagcag ccgcccatca
     7441 cgaagatgcc gacggcggcg agcagcgacc agaagaaccg ctccttgccg tagccgaagg
     7501 ggtgccgccg gtcggcgggc cggcggctgc ggcgcagggc ggcgaggagg aagatctcgt
     7561 tcatgctgtc ggccaccgag tgcgccgcct ccgacagcag ggccggtgag cccgcgaaga
     7621 agccgccgac ggccttggcg accgcgatga ccaggttggc ggccagggcc acgagcacgg
     7681 tgacgcgcgt tctgcgatcg gccctgctct cgccgtcgcg gccgggtttc tgttccgagg
     7741 ctgactcact cacgaaggcc cgactgcccc cggccgcgcc cctcacaccc gccgtgcggg
     7801 tggcccgcca gtgccgacgg ccgaaaacgg ggaacgcgtc cagcatggca gacgaacgac
     7861 gggaggcaga cccatgagcg gcgacgacgc gacgccgggc aacagcggtt acggcaggaa
     7921 ggccttcaag cggtcccgga gccatttcgc ggaccggatc accgcggacg gccgggacgg
     7981 ctggccggtg gaacccggcc gctaccgcct ggtggtcagc cgcgcctgtc cgtgggcgag
     8041 ccgggccctg gtctcccggc ggctgctcgg cctggaggac gccctgtccc tggcggtcgc
     8101 cgacccggtc caggacgacc gcagctggcg gttcagcctg gacccggacg gccgcgaccc
     8161 ggtcctcggc atccgcttcc tcagtgaggc ctacgaccgc cgggagacgg gctacccggg
     8221 cggagtgagc gtgccggcgg tggtggacgt gcccagcggg aagctggtca ccaacgacta
     8281 ccagcagatc accctggacc tcgccaccga gtgggccgcc ctgcaccggc cgggcgcgcc
     8341 cgacctgtat cccgaggcgc tgcgcgccga gatcgacgag gtcatggcgg gcgtctacga
     8401 ggacgtcaac aacggcgtgt accgggcggg cttcgcgacc ggccaggagg agtacgaggc
     8461 ggcgtgcacg ggcgtcttcc ggcgcctgga acagctgacg ccccggctgg aggggcagcg
     8521 ctacctggtc ggcgacacga tcacggaggc ggacatccgc ctgttcacga cgctggtccg
     8581 cttcgacgcc gtctaccacg gtcacttcaa gtgcaaccgc tggaagctgg cggagaaccc
     8641 ggtgctgtgg gcgtacgtcc gcgacctgtt ccagacgccc ggtttcgggg acaccgtcga
     8701 cttcgaccac atcaagcggc actactacca ggtgcacacc ggcatcaacc cgaccggcat
     8761 cgtcccgctg ggcccggacc tggcgggctg gctcgcgccc caccaccgcg aggagctggg
     8821 cggccggccg ttcggcgacg ggacgccgcc gggcccggtc cgtgccgagg aggaggtgcc
     8881 ggcgcgcggc aggccctgac cccttccaac gccgtcccgt tccagcaccg tcccaccgct
     8941 tccaccgctt ccaccgtttc cccgcttcac atcgcacagc gcgcaaggag atccgcatgg
     9001 cgaagacaaa gaagaagaag ctcccgctcg cctacaaacc ggtgggcttc gcgctcgggt
     9061 ggctgggcgg cacgctggcc ggactggcct tccagaagac ctggaagctg atccgcgacg
     9121 aggacgacgc gcccgacgcg ctcgacccgg accgcggctg gggggagatc ctgctggccg
     9181 ccgcgatcca gggcgccatc ttcgcggcgg tgcgcagtgc cgtggaccgg accggcgcga
     9241 aggccatcga gcgctccacc ggcacctggc cgatccccgg caagggcggg cgggactgac
     9301 cgcaccgccc ctcccccgcc gcgacggcac ccggcaggcc gcgttcagcc ctgcttgggt
     9361 gccgtcggcg cgacggccag gcgcagggtg aaggagtgcc ccgccgggtc ggagaagccg
     9421 cgttcctcgt gcggccccgc cgcgtccttg gcctccaccg gccgcccgcc gagcccgacg
     9481 atcgcgcgct cggcctcgtc caggtccgcc accacgaggt ccaggtggac ctggagcgaa
     9541 ttctccgggc ggggccagct gggcggggtg gcgttgacgt cccgccggaa ggccaggcgg
     9601 aagccgcgcg gcccctcgat ctcgatccgg ttggcggtca cgtccgtctc ctccgccccc
     9661 agcaggccct tgtagaactc tgcgagccgc tcgggctcgg cgcagtcgag caccacgacg
     9721 cccgcgttga ccagtgccat gtcgtctcgt tcccctccgg agatgccggg tgtggggcgg
     9781 tctgccccac acctcgtact gtgcggatac ccggcggagc cgggagtaac ggagatcacc
     9841 agcggacgcc gtgtagatca tttagggtac gggcagcctc gtatcgcttc tcggttcaac
     9901 tttctttccg tgaagccgag ttcgagtgcg cgggcggccc tgccgccgtc cgctcgcagg
     9961 gccgggggga ctctgcgctc cgtctcccga aaggaaccac atgcaggacg tccgcttcga
    10021 cctccccttc gacacccccg tcagcccgca tctcgcccac gcccgtgagc gccatctgcg
    10081 ctgggtgcgc gagcgggggc tggtgcgcag cgcggcgggc ttcgaggagt accgctcctg
    10141 ggacctctcc gaggccgccg cccgcaccta cccgcacgcg tcggccgacg acatggtcgt
    10201 cctgatgaac tggttctcgc tggccttcct cttcgacgac cagttcgacg ccgcccggcc
    10261 ggaccgcgcg gagcgcatag ccgaggtggc ccgggaactc atcgccacgc cgctgcgtcc
    10321 ggcggggacc ccgccgcgcg tggagtgccc catcacgctg gcgtgggcgg aggtctgggg
    10381 tcatctttcg gatggcatgt ccctgacgtg gaagtcccgg ttcgcggcgt cctggggccg
    10441 gttcctggtg gcgcactgcg aggaggtcga cctggcggcc cacggccggg ccgccacgct
    10501 ggggatcgag gagtacgccg tcttccggcg ccgcacggtc ggcatccacc acagcatcga
    10561 cgcgggcgag cgcagccgcg gcttcgaggt gccggccgcg gcgatggccc acccgctgat
    10621 ggagcggatg cgggacctgg ccgcggacac catcgggttc atgaacgaca tccactcctt
    10681 cgagcgcgag cgccgccgcg gcgacgggca caacctcgtc gccgtgctgc agcgcgagcg
    10741 gggctgctcc tggcaggagg cggccgacga ggcgtaccgc atgacgaccg actgcctcga
    10801 cgagtacgtc gccctggagg cgcgcgtgcc gcagatgtgc gacgagctgg gtctcgacgg
    10861 cgacgggcgc acgcgggtgc ggctgggcgt ggaggccatc cagcactgga tcaacggcaa
    10921 ctacgagtgg gcgctgacga ccggtcgcta cgcggcggcc aaggacggcc cggtcgccac
    10981 ggccgaacag gccgggcggg gctcggtgga cgacctgctg ggcgtgtagg acgaaagccg
    11041 ccgcccggcc ggtgttccgg ccgggcggcg gctttcgctc ggtcccgcgg ctatcgggcg
    11101 aactccaccg gcaggctgtc cagccgggac tcccaggtgg aggccgtgga ggtcagctcg
    11161 gacgccggca cggccaggcg caggcccggc aggcggtgca gcaggacgtc gacggccgtc
    11221 tcgatgatgg cctgtccgat gttctgcccc gggcattcgt gggggcccgc gctgaaggcg
    11281 aggtgcgagg cgttgccctc gaccgagacg ccggtgtcgg ggcggatctc ggggtcgtgg
    11341 ttgccggccg tgaggcccag cacgagcagg tcgccctcct tgaccggaca gccgcccagt
    11401 tccaggtcgg cggtggcgaa ccggcccggc agcacggcga gcggcgggga gttccacatg
    11461 acctcctcca ccaccgcgga catgttcagc tgcccgctca ccaggccgga cagccgggcg
    11521 gagtcggtga ggacgagctg cagcacccgg gccagcaggt tgctggtcgt ggtgtgggcg
    11581 gtgatcagca ccaggcgcag gtggttgacg atctcgtcct cgtcgaggcc ggagttgtgc
    11641 tcgatgagac cggaggcgaa gtcggacccc ggctccctgc gcttgcgctc ggcgagttca
    11701 ccgaggatgc ccatgatgcg ctcgttgtgc gtgagggcgt ccgcgccgcc cttgatcacc
    11761 tggttgctgg actcggcgag ggtgcgtccc tcccgctcgg cgaggccgaa gacccgggtg
    11821 aggaccagca tgggcaggta ctcggcgaag tcggccacca ggtcggcgcg gccctcgtcg
    11881 gcgaacgcgt cgatctgctt gttggcgaag tgcgtgatgt gccgcctgat gccgcgtccc
    11941 gcgacggcgt acaggttgtc ggtgaccgcg ccgcgcagcc ggcggtgcgg ttcgccgtcc
    12001 tgggagacgc agtcgggccg ccaccccacc atctgcatca gcggcgccgt ctccgcgacc
    12061 cggccgtcct ggaagtcccg ccagatccgc gagtcgcggc tgaactggag ggggttgtcc
    12121 agcactcgcc ggttctcccg gtagccgagc accagccagg cggggacgtc gtcctccagc
    12181 agtaccggcg cgaccgcccc gtgctcgccc cgcagccgcg cgtagatctc gtgcgggtcg
    12241 gtcgccgcgt cgggtccgta gagccggacg gcgccctcgc cgtgggcgac ggggcagccg
    12301 ccgcccgtgg gggcggacgg ggtctggtcg tcgttcatcg gggctccagg gcggcggccg
    12361 agcggtcctt caggtgacgg atcagggtga ccagcacgtc gcggccggct gtggggtcgc
    12421 gggcgtcgaa ggcgacgacc ggggtgtgcg gcgcgatgtc cagggcgtcg cggatctcgt
    12481 cgaccgggta gtcgcgcgag tcggggaaga cattgagcgc gatgacgaag ggtaccttct
    12541 gccgctccat ctcctcgatc gcccggaagc tggaggccag ccgccgggtg tccaccagga
    12601 cgaccgcgcc gagggcgccc ttgaacaggc cgttccacag gaaccagaag cgttcctggc
    12661 ccggggtgcc gaacaggtac agcatcagcg tctcgttgag gccgatcttg ccgaagtcca
    12721 ggctgaccgt ggtctgcgtc ttgtcggcca ccccgatgag ggggtcgacg tcggcgctgg
    12781 cctgggtgag agtctcctcg gtggtcagcg gtttgatgtc gctgacggcg cggaccatgg
    12841 tggtcttgcc cgttccgaag ccgccggcga tcatcacctt caccgagcgg gtgtcccccg
    12901 ccgtggatga ccccggtcgg tcaaagcctt tgaagtccac tgagtacctc ctcaaggagc
    12961 gcgaggtcgg gcccgcggcc ggcatccagt gccgggatgg gatcacgggc ttcgacgctg
    13021 cccgcctgga gcaggtcgga cagcagcacc gcgagaatgt tgaagggcaa gtgcagatgg
    13081 gcgccgagtt cggccaccga aagcgggtcg cggcagcgcc ggaggatctc ctcgtgctcg
    13141 tgctgcatgc ccggtaaggg ggcggcacgc gcgacgacga gcgtcgccac gtcgagggtc
    13201 gacgccgaac cgcccggccc gctgcgccct ccggtgagga cgtagtagcg ctcgagaccg
    13261 gacggatcgg tcggtcggcg gggagcactc atccagagtg ctcctcctgg cgcggcgtgg
    13321 tcccgaggag ttcacccatc cggcgggcca ggtcgcgcat ctgatggccc agcaggccct
    13381 ggtcgagtcc ttcgcgggcg aggacgccga gatacgtctc catgcccgcc cggacgacga
    13441 acaggtgccc gccgtccacc tcgatcatcg ccagccgcag ctgccccgcg tgctgcggga
    13501 actgctcggc caccggctgg gccagcgcct gcaggccggc caccacggcg gcgaagcggt
    13561 ccacgtcgtc ggggtcttcg gcgccgtagg aagtgatcgc cttgccgtcg ctggaggcaa
    13621 cgagggcgaa gcggatctcc tggatgctct ccacaaggtc gcggagcgcc cagctcacgt
    13681 cggttccctg gtgcgtcatg gggactagtc gctctcttca gtgcggtgct cggtggacgc
    13741 gccaccggtg gtcgattcgg aggtgccgac gccggcgccg gggtcgcggc ccgcggtggc
    13801 gaaggcggcg agaccggtga aggacgcgtc cggtggaacg gcggaggcct gggcccggtc
    13861 ggcggcttcg ctcccaggct gctgcgcggc cggcgcggcg cccccggacg cggcggccgg
    13921 ctcggcacgc ctgctccggc gtcggggcag gccgcccggg gtggtctcca ccgcggtgtc
    13981 ggccgcgggc gcggggtcgg ccgcccgtgt ggactcgacc gccggtgcgg gggcggccgc
    14041 cgcctcgacg agcgccgggg gcacgaggtc cgccgcgggg gcggtggcgg cctgcgcggt
    14101 gtccggcacg gtcgcggggg ccgcggcgga cggcagcggg ctgaagtact tgtggggtac
    14161 gacgaccacc acggacgtgc ccagccacgg cgagtcggcg aaggtgaccc ggatgccgta
    14221 gcggcgggcg agggcgccga cgacacggag gccgatgttg gcgtcctccg agatgccgcc
    14281 gagtcccgca ccgggcgagg tgccggccag cgcgtgctcg gcctcgcgct tcttctcgtc
    14341 gctcaggccc ttgccggagt cctggatctc gatgccgacg ccgttgggca cctccttgcc
    14401 ggagacgacc accggctcgg tgggcggcga gtagcgcgcg gcgttgtcca gcaggtgggc
    14461 gaagatcagc gtgaggtggt ccaccaggcc gccgtcgaca cccagttcgg gcaggtggcg
    14521 cagctggacg cggtggaagt ccttgatccg gccgatgccg ccgcgcatca cgctcagcag
    14581 ccgctgcggt tcctgccact gccgtcccgg gcggtccgag ccgccgagca cgccgatgct
    14641 ggcggcgagg cagtccgcgg ggccgatggc ctggtcgagt tccatcaggc cgcgggcgac
    14701 ggtgggcagc cgcccgtgct cgccctgcat ctcgtgcagg cggccacgga gcttgctggt
    14761 cagcacgtgg atgcggttgc cgacgctgat gaccgcctgc tccgcggagg tcgagcggtc
    14821 gaactccgcc tcgacgccga tcagcgcggt acggagcacc ttgcgcagtt cggcctggag
    14881 gtcggcgccg accttggagc actgctcgac ggtcggcagg atgtcgtcga tggcgtcgcc
    14941 ggagcgcagc ctgcgcatcg cgtcgggcag ctgctcgtcg gcgagccggg acaccgcggc
    15001 cagctggtgt cccagctgct cctgccaggc ctcggtccgc tcggcgaacc gggcctcgta
    15061 ggacgtggcc tgctcggcga gccggtcctc gtaggcccgg gtgtgctcgg cgagccgttc
    15121 ctcgtaggtc tgggcctgct cggtgagctg ggcgtccagg tcggagcgct cggcggagaa
    15181 cttgcgttcc aggccggcca cgtgctgctg ccactgctgg gagttctcgg agcgcgcgga
    15241 gcggtgggcg ttctcggccc ggccaagctg ggcgcgggtg cgcaggagga ggcgtacgca
    15301 cacggtgccg gccacggtgg ccgccgcgcc ggcgacggcc acggttattc gctccgagct
    15361 catgaacgtg gcggctaccg tcccgccgcc cagccccagt ggcatgagcc accagctgtg
    15421 ccaggcgaca gggacccgcg ccgccggtgg cggagtggcg agttccatct gcatccttcg
    15481 aagcaaaaca atcgaacagg ggggatggtc tagcaagggt gcgcaagggg gaccgcactc
    15541 agggtgtgca ccacgggccg acccgtcgcg atcgcgtcaa ctcgcagtgc cgctggggag
    15601 cttatcggtt gggaagccta aaagatcaat ttcacggctc cgcggaagtg aggattccgt
    15661 cacgacccgg cagcgggcca gaggtcgaca aatcccccaa ttgaccaggt gcaccgacac
    15721 ggtgcgcccg ggaaaccggg gcctgagcac gcccgccgcc ctgatccggc tgccgcgccc
    15781 gcgggtgccg tccggcccgg ggaatggcac gatcacgtcg gagtcgcaga ccgtgcccct
    15841 gcccccctcc cgagttgcga ggttctccga tgaccaccat gcgcgccgtc agccaggacg
    15901 ttctgggcgg acccgaggtc ctcaaggagg tacgggtcga gcgccccgtt ccgcggccga
    15961 acgaggtgct ggtccgggtg cgtgccgccg gggtgaaccc caccgactgg aagcaccggg
    16021 cggacggcgg cttcctcggc gagccgccct tcgtactggg ctgggacgtc tcgggcacgg
    16081 tggagtcggt ggggatcggc gtcgccgcgt tccggccggg cgacgaggtc ttcggcatgc
    16141 tctcctatcc cttcggccac ggttcgcacg cggagtacgt gacggctccc gcgcgcacct
    16201 tcacgcacct gcctgccggg accgaccacg tccgggcggg cgcgctcccg ctggtgtccc
    16261 tcacggcgtg gcaggccctg gtggaacggg cggacctcca gccggggcag cgggtgctga
    16321 tccacgcggc ggccggcggc gtggggcacg tggcggtgca gatcgccaag gcgcgcggcg
    16381 cccacgtcat cggcaccgcc agcgcgggca agcacgcgtt cctgcggtcc ctcggggcgg
    16441 acgaggccgt ggactaccgg gagacggact tcaccgaggc ggtgcgcgac atcgacgtcg
    16501 tcctggacac gatcggcggt gacacgtcgc tgaggtcact gcgcgtgctg cgcccgggcg
    16561 gggtggtggt gtcgatcctg ccggtcgggt ccggcgagtt cttcgaggag gccgggcggc
    16621 tcggggtgcg ggcggtacgg atgctggtcg acgccgaccg ggccgacatg cgggagatcg
    16681 cccggctggt cgaggccggg aagctggagc ccaccatcgc gaagacgttc ccactggccg
    16741 aggcggccgg ggcgcacgcc ctgggggaga ccggccgcac caccggcaag atcgttctcg
    16801 tggtcgactg aacggtcggc acggccgtgc gatgagacgt cggcgacata tgtcagtcga
    16861 acatgctcaa actcgctcga ccgaggtaac tttctgagca gactgggtag ttgggccccc
    16921 atgacaggcc ggaacgggcc ggaacaggct ggaggcgacg tcgtcgtgcg gcaggaatcc
    16981 ccgtcgccca cccgccatct gcgggtgcgc cacgagcgcg ggcacgcggt gctggagttc
    17041 cggggcgaga tcgacatcgc gtccgccacg gagatcgccc cgcacctgga ccgggagacg
    17101 cggcgccccg gcgcccgcgt cgtgctcgac ctcggcggga tcgagttctt cgactgctcc
    17161 gggctccggc tgctcgcccg ggcccgcaac caggtgctcg cgggcggcgg agaggtacac
    17221 ctggtgtgct cgcacccgct caccctgcgc atgctgcgga tcaccggcct gacccggctg
    17281 ctgccaccgc ggccgaccct gcaggaggta ctcggccccg ccctgccgac cgctcgccga
    17341 acggggtgct gaccggctca ccaccaccgg cgcggcacac ggacccggcg gccgtcacgg
    17401 tgtccggctg agttgaaccg gggcggccgt cacggtttcg gccgacggtg catcggaggt
    17461 ggccgtcgac ggtcgcgagg accacaccgc ctccccgcgg gtgagccccg gcagccgcaa
    17521 ttcacccggg atccccgcgt cctgccgccc gttctccaac tgctccgtct ggcgggggag
    17581 atgaggggca tccgggtgag taggaaggag ggccgtcgcc atgacgactc ccgtcaagaa
    17641 gcccacgagt gacaaccgga agcccgcgcc gcgcatgccc ggctgggcga aggcgctgac
    17701 cgcggtggtg ctggtgctcg cggtgctgtt cgccgggctc cggctgagcg tcctgcccgg
    17761 cctcaaggac ctgttcggct cggagacgca ggaccggtcc ggaccggcgc tgctgaagtc
    17821 catccaggac atgagccgtt acgacgcggc gtccggcaac ttccaggtcg tcgtggacct
    17881 ggagaaggac accaagttcc tgccggacgc gatccgcggg acccgcaccc tgtacgtggg
    17941 ggcgggcacc gtggacgcct atgtcgacct cggaaagctg ggcgaggacg atgtgcaggt
    18001 cgacggggac cggacgtcgg ccacgctgcg gctgccgcac gcggcgctcg gcgagccggc
    18061 cctcgacccc gaccgctcct acgcggtctc caagcagcgc gggctgctgg accgcctggg
    18121 cgacctgttc tcggacaacc cgaacggtga gcaggccgtg cagaagctcg cgtcccggca
    18181 catcggcgag gcggcgaagg acagcgagct gaagacccgg gccgagagca acaccacggc
    18241 gatgcttcag ggcctgctgc gctccctggg cttcgaggac gtgcgggtgg tgtacaaggg
    18301 ctgagccccc cggcgggagg gcgcgcgggt ggcggcgggc ggagcggatg cggcccgttg
    18361 cgcattgccg ggcatcctcg gcggcgcggc gggtaaccgc ccttccacgc ggggacgttg
    18421 acgactggag gaccgacatg gcacgtgccg tctcaggatt gcgtctgtgg ccgcgccccc
    18481 gcgccgcaga gacgcggaag gccgacccgc ccgaacggca cgcgctcgcc ctgccgttgc
    18541 ggctgctggc cacggcgtgc gcgttcgtct tcatggtggc gttcgcggtg gtgctggcgc
    18601 ggctgaccct gcacccctcc cccgcctccg aggccctgac gcacaccaac atgcgaccgg
    18661 gcagctcgct gcgggcctac ctggaccagc ccgcactgcg ggacgccgtg aagcagatcg
    18721 gcgggaacat cctgctgggc gtgccgttcg gcgtgctcgt gccggtcgtg gcgccgcgca
    18781 cgcgcggggt gctgcgggtc ctgctgctga cggccgtggt gatgctgctg gtggagttcg
    18841 cgcagggcgc gctcgtcacc gggcgggcct tcgacgtcga cgacgtcatc ctcaacacca
    18901 gtggcgcgct gatcggatac ctgctcctcg gccggcggat gagccgcacg gtgcacgcac
    18961 gcaaggcccg gggctgaaga cggcacttct ggtccgtacc aatgtattga ccacccctta
    19021 cctcactatt tgaataaaga ggcgacatcc ccactccacc cccacctcgg tcggcgctcc
    19081 cccgcggagc gccgtacgga agggagagcc gtggtccgcc cacgcctgct ccgcagatgt
    19141 ctcctcgccg ccaccctgtc cgccgggctc gccgcgtccc tcgtgaccgg ccccgcccag
    19201 gcggagcccg aaggccccgc gaccgccggg accgccggcg cctcggccgc cgccgtggtc
    19261 ttctccgaca ccttcgacgg cccggccggc gcggccgtcg actcctcgaa gtggcagatc
    19321 gagaccggcg acaacgtcaa caaccacgaa cggcagtact acacctccgg caacaagaac
    19381 gccgccctgg acggccaggg ccacctggtc gtcacggccc gcaaggagaa cccggccaac
    19441 taccagtgct ggtacggcac ctgccagtac acgtccgccc ggctcaacac ctcggggaag
    19501 ttcacggcgc agtacgggca cgtcgaggcg cggatgaagg tgccgcgcgg gcaggggatg
    19561 tggcccgcgt tctggatgct gggtaccccg gtgaactggc cggactccgg cgagatcgac
    19621 atcatggaga acgtcggctt cgaaccctcc accgtgcacg gcaccctgca cggccccggc
    19681 tactccggct ccggcggcat cggcgccggg tacaccctgc cgggcggcca gtccttcgcg
    19741 gacgccttcc acaccttcgc cgtcgactgg gcgcccgact cggtcacctg gtcggtggac
    19801 ggcaacgtct accagcggcg caccccggcc gacctgggcg gcaggcagtg ggtgttcaac
    19861 aggccgtact tcctgatcct gaacctggcg gtcggcggct actggccggg cgacccggac
    19921 ggctccacgg tcttcccgca gaccctggtc gtcgaccacg tctcggtgac gaccggcgac
    19981 tcaccggcag ggggcgcgat ccggggcctg gccggcaagt gcgtggacgt cgccgcggcg
    20041 gacaccgcca acggcacgcc cgtgcagctc tacgactgca acggcaccac ggcccagcag
    20101 tggacggtgg gctccgacgg cacgatccgg gcgctcggca agtgcctgga cgtgaacgcc
    20161 ggcggcacgg cggacggcac ggtcgtccag ctgtgggact gcaacggcag cgccgcccag
    20221 cagtgggtcg tcaccgcggc gcgcgacatc gtcaatccgc aggccgacaa gtgcctcgac
    20281 gtcaccggca acaactcggc caacggcacc cggctgcaga tctggacctg cgcgggcacc
    20341 gccaaccaga agtggacggt cggctgagcc accgggcggg gccggcccgg acgtccccta
    20401 gcgccgggtc caggtgaact tgtccccgcc cacccagcgg accacgtccg ggtcgtccag
    20461 gtcgtggacc gtgatgccga aggccgcggc cgcctccagt acgtcggtga cgtccctggc
    20521 cgcaccgacc acctggccgt cgatctcgac gatccggaac gggggcgtcc ccggctgaac
    20581 cccgagtacg aggatccgcg ggctgccgat gtgcgggctg tcgatttcgg tcatgcctag
    20641 agggtaggcc gcgggtcgcg ccgggcgccg tgtccgtggt gcgggccccg ggccgctggg
    20701 gaaccctgga cgtggcggag gagccgtcgc gagggccggc cggaggtggt ggcgatggag
    20761 cccgtcgagg cactggagcg gatcgcgttc ctgctggaac ggtcccaggc acccacgtac
    20821 cgcgtgcgcg ccttccgcac cgcggcgcgg gtcctcggcg acctcggcgc ggacgggctg
    20881 cgcgagcggg cgggttcgct ggagtcgctg aagggggtcg gtcccaggac ggcgcaggtg
    20941 gcgcgggagg cgctggccgg ccgcacaccc ggttacctgg agaaactgga ggacgaggcg
    21001 gaggccccgc tcgccgaagg cggtgagcg
//
