LOCUS       NZ_JADEWH010000020     20930 bp    DNA     linear   CON 23-DEC-2023
DEFINITION  Nodularia sp. LEGE 06071 N071000020, whole genome shotgun sequence.
ACCESSION   NZ_JADEWH010000020
VERSION     NZ_JADEWH010000020.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nodularia sp. LEGE 06071
  ORGANISM  Nodularia sp. LEGE 06071
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales;
            Aphanizomenonaceae; Nodularia.
REFERENCE   1  (bases 1 to 77825)
  AUTHORS   Castelo-Branco,R., Eusebio,N., Adriana,R., Vieira,A., Brugerolle De
            Fraissinette,N., Rezende De Castro,R., Schneider,M.P.,
            Vasconcelos,V. and Leao,P.N.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-OCT-2020) Cyanobacterial Natural Products, CIIMAR,
            Terminal de Cruzeiros do Porto de Leixoes, Matosinhos 4450-208,
            Portugal
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2016
            Assembly Method                   :: SPAdes v. nov/18
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 30x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 12/23/2023 19:29:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,867
            CDSs (total)                      :: 4,805
            Genes (coding)                    :: 4,703
            CDSs (with protein)               :: 4,703
            Genes (RNA)                       :: 62
            rRNAs                             :: 6, 7, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 3, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 4 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 22 of 102
            Pseudo Genes (incomplete)         :: 84 of 102
            Pseudo Genes (internal stop)      :: 12 of 102
            Pseudo Genes (multiple problems)  :: 15 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:23:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 23350
            Orig. end                         :: 44280
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JADEWH010000020.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20930
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20930
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20930
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10930](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10930
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(83..98)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 23.15"
                     /tool="antismash"
     gene            346..1023
                     /locus_tag="IQ233_RS22050"
                     /old_locus_tag="IQ233_22050"
     CDS             346..1023
                     /EC_number="3.2.2.27"
                     /GO_function="GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017651720.1"
                     /locus_tag="IQ233_RS22050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_22050"
                     /product="uracil-DNA glycosylase"
                     /protein_id="WP_194003167.1"
                     /transl_table=11
                     /translation="MSSDIQLNLFDDTNSNPRDLIPTDAKIPITPGTYANMTELAQDCN
                     QCHRCGLGDNRTHAVVGRGHLQAPIMLIGEAPGQNEDETGLPFVGRSGQLLEKILASVN
                     LSTEQDIYIANINKCRPPENRTPNPDEMAACIPYLLEQIRLVDPKIILLTGATAVKGIT
                     GDKRGITKIRGQWLEWEGRLCMAIFHPSYLLRNPSKEVGKPKWLMWQDIQAVRAKLDEI
                     TMN"
     gene            1036..1245
                     /locus_tag="IQ233_RS22055"
                     /old_locus_tag="IQ233_22055"
     CDS             1036..1245
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010994931.1"
                     /locus_tag="IQ233_RS22055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_22055"
                     /product="toxin-antitoxin system, antitoxin component, Xre
                     family protein"
                     /protein_id="WP_194003169.1"
                     /transl_table=11
                     /translation="MHTEDRLKQKLWEKISQMPPENILLVTDFIDSLDQPNSHRMLTLA
                     AAKLSEPALQKVWDHPDDAEYDQL"
     gene            complement(1415..1993)
                     /locus_tag="IQ233_RS22060"
                     /old_locus_tag="IQ233_22060"
     CDS             complement(1415..1993)
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016951608.1"
                     /locus_tag="IQ233_RS22060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_22060"
                     /product="Uma2 family endonuclease"
                     /protein_id="WP_194003171.1"
                     /transl_table=11
                     /translation="MVAIPQKPPKMTVQEYLEWEPQQDIRYEYVNGKIFAMTGGTIPHN
                     DIALNLYTALRPHLRSRGCRVNVSDVKVQVTPNSLYYYPDLIVSCDPQDLKAHKFIEYP
                     RIIVEVLSPGTSAKDRGEKLSDYLKMPTLQEYLLIDSEKISVERYSRGEGRMWLYYPYI
                     AGDIITLSSIEFECPIELLYENVVFATKE"
     gene            2111..2374
                     /locus_tag="IQ233_RS22065"
                     /old_locus_tag="IQ233_22065"
     CDS             2111..2374
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IQ233_RS22065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IQ233_22065"
                     /product="hypothetical protein"
                     /protein_id="WP_194003173.1"
                     /transl_table=11
                     /translation="MWSLIFLVVFFAWIFWMKNAASSASKNSRNRRQRNFRHSNSDYTS
                     SDIHYSGSYDSGSSSCDSSGYGSSNCDSGGSDGGGGCDGGGF"
     gene            complement(2371..3003)
                     /locus_tag="IQ233_RS22070"
                     /old_locus_tag="IQ233_22070"
     CDS             complement(2371..3003)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017742876.1"
                     /locus_tag="IQ233_RS22070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_22070"
                     /product="hypothetical protein"
                     /protein_id="WP_227789250.1"
                     /transl_table=11
                     /translation="MKAKVKNKNYGLWLCAFGLWLVAANSMNNSAFANTPVLLTQRQAV
                     KNGLSSTCSEQSLELLTIQLLQDLPSYANRVTQRARRRSRSSDIYSYVLLAGKPEFQPL
                     PINSGGYNADEQKSNDTGVEQVFFTTKERQYIAGKIVESQQFHWLLLTKSNSGWRLVMM
                     FTQIGDYPQKQQVVSPPRDSSKGVIAQAVKAWLRDCQAGSVRMRTGI"
     gene            complement(3000..3740)
                     /gene="pyrF"
                     /locus_tag="IQ233_RS22075"
                     /old_locus_tag="IQ233_22075"
     CDS             complement(3000..3740)
                     /EC_number="4.1.1.23"
                     /GO_function="GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010997134.1"
                     /locus_tag="IQ233_RS22075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_22075"
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="WP_194003175.1"
                     /transl_table=11
                     /translation="MIYPERSRRANDQIIVPLDVPDLQSAIALVDQLPQVNFWKVGLEL
                     FTSSGPTILEVLKSRQKRIFLDLKFHDIPNTVAGACRSAASYGVDLLTIHATAGRDALK
                     AATEAVQVGAMQAGVKPPQLIAITLLTSISSRQLAFDLKIPLELPEYALEMALMAQECG
                     LNGAVCSPQEVAQLRQTCGDDFLLVCPGVRPSWAEKGDQKRSLTPAQAIKAGANYLVIG
                     RPITAAAEPELAWKKIVEELTTVG"
     gene            complement(3754..4953)
                     /gene="tyrS"
                     /locus_tag="IQ233_RS22080"
                     /old_locus_tag="IQ233_22080"
     CDS             complement(3754..4953)
                     /EC_number="6.1.1.1"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="tyrS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010997133.1"
                     /locus_tag="IQ233_RS22080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_22080"
                     /product="tyrosine--tRNA ligase"
                     /protein_id="WP_194003177.1"
                     /transl_table=11
                     /translation="MTQNFSWLHRGIVEIFPQPIDADSETESLEKRLVTTNRPLRIKLG
                     IDPTGSDIHLGHSIPVRKLRAFQDAGHTAVLIIGDFTARIGDPTGKSEVRRQLTEADVA
                     QNAQTYLEQVRPILDFDTPGRLEVRYNSEWLSHLDLGKILELLSTMTVGQMLAKEGFAE
                     RYKKENPIFIHEFLYPLMQGYDSVAVEADVELGGTDQKFNIAVGRDLQRHFGQKPQFGL
                     LLPILIGTDGMQKMSKSLGNYVGLSEHPAQKYQKLQGVPDNLLSQYFELLTDFSLEKLP
                     ENPRDRQMLLAWEVVKQYNGETAANEAKEAAKSGGKEGAVPEFSLAEVSEFPVKLAYLL
                     NVTGLCKSTGEGKRKIQEGGVRLDGDRMIDIDTTFEQASELHGRVLQVGKNKFVRLVNK
                     "
     gene            5241..7049
                     /locus_tag="IQ233_RS22085"
                     /old_locus_tag="IQ233_22085"
     CDS             5241..7049
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013191131.1"
                     /locus_tag="IQ233_RS22085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_22085"
                     /product="transglycosylase domain-containing protein"
                     /protein_id="WP_227789252.1"
                     /transl_table=11
                     /translation="MLASSIVAGGLVGLAISFRNLPDVRQLRNFFPSETTYIYDINGKL
                     LTSLHGEANREVMALDRISPHLKRAVLASEDSHFYDHHGINPSGVGRALIVNLAAGSVR
                     EGGSTITMQLVKNLFLSQKRAFTRKLAEGVLAIRLEQILGKDQILEMYLNQVYWGHNNY
                     GVQTAARSYFDKSAEILTLAESAMMAGLIQAPEEFSPFASMELAKRKQREVLGRMLELN
                     WISQQEYDDALKQELKLGRIRSFQGSALPYVTNTVSQELVKKFGREALIKGGMRVQTTI
                     DANFQTMAEKTVSKWSRTLRGQGLRGNEIALVAIDPRTHFVKALVGGVDSRASEFNRAT
                     QAQRQPGSAFKPLVYYAAFATGKYTPDTVVQDTPVSYRDGSGWYSPKNYDSGFQGAITI
                     RSALAQSRNIPVIKVGMSIGMNKVVEASRTLGIMSPMAPVTSLPLGAIGITPLELASAY
                     ATFANYGWQSPPTVMARVTDSSGNILLDNTPKPQLVLDQWASAATIDVMRSVVTSGTGK
                     GADIGRPSAGKTGTTSSERDIWYVGTVPQLTTAVWVGRDDNRPLSRGATGGGMVAPIWK
                     DFMQQALKGVPAENFKPPSQFQRPKS"
     gene            complement(7135..7458)
                     /locus_tag="IQ233_RS22090"
                     /old_locus_tag="IQ233_22090"
     CDS             complement(7135..7458)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006194378.1"
                     /locus_tag="IQ233_RS22090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_22090"
                     /product="DUF1825 family protein"
                     /protein_id="WP_194003181.1"
                     /transl_table=11
                     /translation="MGFFDSDIVQQEAKHLFEDYQTLINLGNNYGKFDREGKKLFIEKM
                     EVMMDRYRVFMKRFELSEDFMAQMTVQQLKTQLGQFGVTPQQMFEQMHLTLQRMKTELE
                     QQQ"
     gene            complement(7734..8180)
                     /locus_tag="IQ233_RS22095"
                     /old_locus_tag="IQ233_22095"
     CDS             complement(7734..8180)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016868364.1"
                     /locus_tag="IQ233_RS22095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_22095"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_194003183.1"
                     /transl_table=11
                     /translation="MTNQPVHVAIAILYQEDKFLMQLRDNIPGIIYPGYWGLFGGHLEL
                     GETPDVAVKREVIEEIGYTLPSFSEFGCYANDAVVRHVFHAPLLVELNQLVLNEGWDMG
                     LLTPKDIRQGNCYSPIADEIRPLGTIHQKIMLDFISQSILDFRF"
     gene            complement(8212..8613)
                     /locus_tag="IQ233_RS22100"
                     /old_locus_tag="IQ233_22100"
     CDS             complement(8212..8613)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006194375.1"
                     /locus_tag="IQ233_RS22100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_22100"
                     /product="hypothetical protein"
                     /protein_id="WP_194003260.1"
                     /transl_table=11
                     /translation="MQPTKKFHLCSMIPYRQGITLLLVAGLCSCSSLTIPSFKAGNLSI
                     GSNVTLIQEIKPETDQETIVYVQGKVEKQVPLVNQWAYQINDSTGKIWVITNQPNLKEG
                     AQVVIKGKVRYKSIPLADQEFGEVYLEES"
     gene            8875..9750
                     /gene="folD"
                     /locus_tag="IQ233_RS22105"
                     /old_locus_tag="IQ233_22105"
     CDS             8875..9750
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /gene="folD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010994389.1"
                     /locus_tag="IQ233_RS22105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_22105"
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD"
                     /protein_id="WP_194003262.1"
                     /transl_table=11
                     /translation="METKTAKLLDGKALADKIHQELSAITTETQAKIGRSPGLAVLMVG
                     DNPASAAYVRNKERACAKVGIASFGQHFPTETTQGELEAVIAALNEDERVDGILVQLPL
                     PSHLDAVALLNKIDPDKDADGLHPVNLGRLVRGEPGLRSCTPAGVMRLLQEYEISLQGK
                     HAVVVGRSILVGKPMALMLLEADATVTIAHSRSLDLGTITKNADLIIAAVGRPGLITAQ
                     MVKSGSVVVDVGMNRVTDASGKSRLVGDVDWESTAGVAEYITPVPGGVGPMTVAILLQN
                     TVASYLKKAK"
     gene            10001..10930
                     /locus_tag="IQ233_RS22110"
                     /old_locus_tag="IQ233_22110"
     CDS             10001..10930
                     /EC_number="2.5.1.10"
                     /GO_function="GO:0004337 - geranyltranstransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010994390.1"
                     /locus_tag="IQ233_RS22110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_22110"
                     /product="farnesyl diphosphate synthase"
                     /protein_id="WP_194003185.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.6e-63, bitscore:
                     206.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVAADNFQKMKEEATFNLVAYLKERQKLCETALDQAIPVIYPEKI
                     YESMRYSLLAGGKRIRPILCLAACEIMGGTIEMAMPTACATEMIHTMSLIHDDLPAMDN
                     DDYRRGRLTNHKVYGDNIAILAGDGLLAYAFEFVATQTPENVPRERVIQVIARLGKALG
                     AAGLVGGQVVDLDSEGKSDISLETLNFIHNHKTAALLEASVVCGGMIAGASAEDVQRLS
                     RYSQNIGLAFQIIDDILDITATQEQLGKTAGKDLIAKKVTYPSLWGLEESRSKAQQLVE
                     AACKELETFGKLAQPLQALAHFITSRNH"
     gene            11127..11582
                     /locus_tag="IQ233_RS22115"
                     /old_locus_tag="IQ233_22115"
     CDS             11127..11582
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015207140.1"
                     /locus_tag="IQ233_RS22115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_22115"
                     /product="divergent PAP2 family protein"
                     /protein_id="WP_194003188.1"
                     /transl_table=11
                     /translation="MQDIGNILDNRVLLVALVACLIAQGLKLVVEVVKNRKLNVRVLVT
                     TGGMPSAHSALVTALAAGVGQSLGWASPEFALATVFAIIVMYDAAGVRQAAGKQARILN
                     QMIDELFHEKPDFSQDRLKELLGHTPVQVIVGSALGITIYWLARSAY"
     gene            complement(11691..12347)
                     /locus_tag="IQ233_RS22120"
                     /old_locus_tag="IQ233_22120"
     CDS             complement(11691..12347)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006194371.1"
                     /locus_tag="IQ233_RS22120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_22120"
                     /product="hypothetical protein"
                     /protein_id="WP_194003190.1"
                     /transl_table=11
                     /translation="MQPNFVQKFDNLSSALALAAAGLIGSMTSVTAQQNVPVCQPPRPG
                     EYLLLVVSPTANSQKQLLSALPNQIQATTCQYLSDTVTRIGGFNRIDDANRWATYVNSI
                     VGLSATITTRPAAANVTQTPNLPQTISFNPQVLGDGYAVLVEYFNKPELANSIHQVVGG
                     NIGFASYGQRPYLLAVYTGNQQEAYNALQKLTERGFFAVLVDGSKVMLLRSSVRL"
     gene            complement(12659..12988)
                     /locus_tag="IQ233_RS22125"
                     /old_locus_tag="IQ233_22125"
     CDS             complement(12659..12988)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016875706.1"
                     /locus_tag="IQ233_RS22125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_22125"
                     /product="MgPME-cyclase complex family protein"
                     /protein_id="WP_194003192.1"
                     /transl_table=11
                     /translation="MKTYYYALASHKFLIQEEPTAEVLKERTRHYHEQEKEIDFWLVNQ
                     PAFLESPEMAEVKAKCPRPAAAIISTNAQFITWLKLRLEYVITGEFQAPSETISDPLAS
                     LSSVS"
     misc_feature    complement(12981..12996)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 23.6"
                     /tool="antismash"
     gene            complement(13069..13851)
                     /locus_tag="IQ233_RS22130"
                     /old_locus_tag="IQ233_22130"
     CDS             complement(13069..13851)
                     /GO_process="GO:0030638 - polyketide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006194369.1"
                     /locus_tag="IQ233_RS22130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_22130"
                     /product="ester cyclase"
                     /protein_id="WP_194003194.1"
                     /sec_met_domain="PF07366 (E-value: 5.1e-10, bitscore: 31.5,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTESNNLPLWVQHRDKVLEQSTDIEWRYGKFPDYTRSNENIAR
                     ESTRNHPEGSLEAIVQNLVRTFDVEANFKTNPQQWISVVNEKFRMSTNGGPGYTVSDLV
                     ESGTYKLLIGNTKHYKAAEENFETSTNLFHTAFPEGFTWEVLEVFSAPPTVAFKWRHWG
                     HFKGAYKDNAPTGETIEVIGMSVAHVTDDLKILSLEHYYDNTKFLDKLTAKGQQETGEQ
                     KHKKPNFWNFFSQLWHWQEKPRTGVAKTSACPFSALMK"
     gene            complement(14046..14789)
                     /locus_tag="IQ233_RS22135"
                     /old_locus_tag="IQ233_22135"
     CDS             complement(14046..14789)
                     /EC_number="2.6.99.2"
                     /GO_function="GO:0033856 - pyridoxine 5'-phosphate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006194368.1"
                     /locus_tag="IQ233_RS22135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_22135"
                     /product="pyridoxine 5'-phosphate synthase"
                     /protein_id="WP_194003196.1"
                     /transl_table=11
                     /translation="MPTLGVNIDHIATIRQARRTVEPDPVAAAVLAELAGADGITVHLR
                     EDRRHIQDRDVLLLRQTVRSHLNLEMAATDEMLAIALDIKPDYVTLVPEKREEVTTEGG
                     LDIVGQIARIGEIVDKLQSVGIPVSLFIDAQPAQIEASVKVKAQFIELHTGQYAEAKDE
                     THRQQELAVLAQGCEQAIKAGLRINAGHGLTYWNVYPVAALPGMEELNIGHTIISRAAL
                     VGIERAVREMKQAITVNSYHNFLAR"
     gene            14970..15608
                     /locus_tag="IQ233_RS22140"
                     /old_locus_tag="IQ233_22140"
     CDS             14970..15608
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009454908.1"
                     /locus_tag="IQ233_RS22140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_22140"
                     /product="Uma2 family endonuclease"
                     /protein_id="WP_194003198.1"
                     /transl_table=11
                     /translation="MLLELQQIIVKPGQEMLLKDISWQQLENILAEMGEKRAARISYSD
                     GWLEIMVPLPEHEKDKEIVGELVRILLDYLQIDFEPFGSTTLKNEQMRQAVEPDTCFYI
                     QNQAAVIGRNRLDLTVDPPPDLAIEIDITSRTRFDNYEILGVPELWRYTKEGLEISVIQ
                     EGKYIKVPSSPNFPDIPIVELINEYVQQCLTIGRSQAIRNFRTWLNSNL"
     gene            complement(15649..18174)
                     /locus_tag="IQ233_RS22145"
                     /old_locus_tag="IQ233_22145"
     CDS             complement(15649..18174)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1282:
                     extracellular ligand-binding receptor"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012410137.1"
                     /locus_tag="IQ233_RS22145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_22145"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_194003201.1"
                     /transl_table=11
                     /translation="MAKFALLIGVSEYEGGLPPLPAAVKDVEAMERVLQHPEIGNFDVE
                     KLVNPQRQEMAEAIEILFKGINGNGRQKDDLILLFFSGHGIKDERGHLYFATRNTRKTD
                     NGLLLQATTVPASFVHDVMSNSRSKREVVILDCCFSGAFAEGMSAKDNGFVDVKNQLGG
                     EGRAILTSSTSTEYSFEDTGTDTSIYTRYVVEGLGTGVADKDKDGWISVDELHEYATRK
                     VQEASPAMKPQIYAIKEGYKINLAKAPNDHPHLQYRVEVEYWVEGGNGEISSTGRSALE
                     ELRNKLQLTTEEAKGIENQVLEPFKIYQQKLSRYEQALGKEIELKFPLSDKAITDLKRF
                     QQVLGLTDEAIALIEAPIIAKQQTNKTPVSSDIASSLNSNILNKNTGLGIIIGTIIGGT
                     VFAMFLRPSVPKSCAVDTYTFSDKMSVGEEILLTQNTNPDKQAGVKALAKGDCQTAINK
                     LNLYRQANRTNRSDPEALIYLNNAKALQQTQRLKIAVSVPIGSNPDVAQELLRGVAQAQ
                     NEVNNNNGIQGKLLLVEIANDNNDPVQSERIASQFVKDNNILAVVGHNTSDASLRAAPK
                     YELGGLVMIAPTGFSDGFSNAGTYIFRAIPRIRLSAVKLANYIITTVDTSNIAICRDFR
                     NLDNDSVRDHFVTAVVEARATINNTHCDLSDDNLNAEVKISEAINSGANALFLAPHIDR
                     ISNAIKLAKAANQRGLPIFSSPTMYTNETLEKGKADVNGMVLTAAWHPQAFPNNPFANN
                     ALNLWGGIVNWRTATAYDATKAIIKGLQQSNTRSELQQVLRNSNFSADGGAVGNIKFEP
                     SGDRKGDFVLIKIQKKSGIDKYEFVRINP"
     gene            complement(18205..18582)
                     /locus_tag="IQ233_RS22150"
                     /old_locus_tag="IQ233_22150"
     CDS             complement(18205..18582)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015079175.1"
                     /locus_tag="IQ233_RS22150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_22150"
                     /product="hypothetical protein"
                     /protein_id="WP_194003203.1"
                     /transl_table=11
                     /translation="MSSQSNVTLTITLANPDLDAEEQERETHNLLREIKELDVESAGLV
                     AVTEIPEASKPVGGFLLGVLRAEVSIGNTKKLLGFLGDRLGNKTIELEVEANGKKLKIK
                     ASSSQELITAIEQAQKFIAGN"
     misc_feature    18681..18697
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 23.32"
                     /tool="antismash"
     gene            complement(18733..19515)
                     /locus_tag="IQ233_RS22155"
                     /old_locus_tag="IQ233_22155"
     CDS             complement(18733..19515)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016870495.1"
                     /locus_tag="IQ233_RS22155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_22155"
                     /product="ABC transporter permease"
                     /protein_id="WP_194003205.1"
                     /transl_table=11
                     /translation="MSRYWQLLGIFWSTAIAAEMEYRLNFLIATLSSLGNLAGSLFGLF
                     LFYRTDYTFPGWSWFAALLVLGIFTLLQGFAATFLAPNLNRIVRHVQEGTLDFVLLKPI
                     RSQFWLSTHTLSPWGVPDLVFGSIVIGYAGNRLGLGINNYLMSAVPLLFGLVILYSLWF
                     MLGATSIWFVKIYNATEVLRGLLEAGRYPMVAYPTAYRFFFTFVVPVAFLTTIPAEAML
                     GRGQISWSIGAGVLAIVLFWVSSVFWRFALRFYTSASS"
     misc_feature    complement(19546..19564)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.53"
                     /tool="antismash"
     gene            19634..19816
                     /locus_tag="IQ233_RS22160"
                     /old_locus_tag="IQ233_22160"
     CDS             19634..19816
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006194362.1"
                     /locus_tag="IQ233_RS22160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_22160"
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="WP_194003207.1"
                     /transl_table=11
                     /translation="MIKLDQFLKFMGVTSTGGQAKLIILDGGVKVNGTVETRRGRKLVL
                     GDKVTVEGQTFEVEL"
     misc_feature    complement(20269..20280)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
ORIGIN
        1 gcaatattag tttggtacag ttccagacga ctttggaatt gcggctcttg caaagtacca
       61 aataaagatg aaactgacaa caggattgct atcggcgtta ggacaaaaaa taaaatcaac
      121 cgcttaatcg tcattattcc cctttaaaaa ttcaccaggg caacgcgtac cctttggaaa
      181 ttatcgcaag aaaacgccga aggttgatca atatattcat attgtcacgg ttggcgatgc
      241 tttacggtac agcgtagcga tcgccatcgg aatcgataca atggtaatat catgactcag
      301 taagcaatag cgccatctgg tgctaaccct aaaattctgg ttttaatgag cagcgacatc
      361 caactaaacc tcttcgatga caccaactcg aacccacgag atttaatccc cacagacgca
      421 aaaattccca ttacacctgg aacctatgcc aatatgaccg agttggcaca ggattgtaat
      481 cagtgccatc gttgtggctt gggagacaat cggactcatg ctgtggttgg gcgtggtcat
      541 ctccaagcac caattatgtt aataggtgaa gcaccaggtc aaaacgaaga tgaaaccggt
      601 ttaccatttg taggtagatc aggacagtta ctagagaaaa tattagcatc tgtgaatctg
      661 agtaccgaac aggatatata tattgccaat atcaataaat gtcgtccacc agaaaaccgc
      721 acccccaacc ctgatgaaat ggcggcttgc ataccctact tactagaaca aattcgcctt
      781 gttgatccga aaatcatttt actcacaggt gcaactgcgg tcaaagggat aactggcgat
      841 aagcggggaa ttacaaaaat tcgcggtcag tggttggagt gggaagggcg tttatgtatg
      901 gcgatttttc acccctctta cttgttgcgt aatccttcta aagaagttgg taagcctaaa
      961 tggttaatgt ggcaagatat ccaagcagta cgtgccaagt tggacgaaat cactatgaac
     1021 taagagaagt aaaaaatgca cacagaagat cggttaaaac aaaagctatg ggaaaaaatt
     1081 agccaaatgc ctcctgaaaa cattttgcta gttacagact ttatagactc tttagatcag
     1141 cctaattcac accgaatgct cactttagca gctgcaaagc tttctgagcc agctttgcaa
     1201 aaagtctggg atcaccctga tgatgctgaa tatgatcaac tataggaatc cggtttgatt
     1261 tatgaaaaaa ttaagtattg tagggtgcgt taggatgaag tccgtaacgc accattatta
     1321 aggctttggt gcgttacgct accgctaaca caccctacgt gtctattcaa aaatcaaata
     1381 gtagtcctat atgaatttgg cgatgttttt ttagttattc tttagttgca aatacaacat
     1441 tttcatagag gagttcaata ggacactcaa attcaatact tgatagagta ataatatctc
     1501 ctgctatata gggataataa agccacattc taccttcacc ccgtgagtaa cgctcaacag
     1561 aaattttttc agagtcaatc agcagatact cttgtaaagt aggcatcttc aaataatcag
     1621 atagtttttc acctctatct ttggcgctag ttcctgggga aagaacttcg acaattatcc
     1681 gaggatattc aataaatttg tgagctttaa ggtcttgagg atcacaactg acaatcaaat
     1741 caggataata gtaaagactg ttgggagtga cttgcacctt cacatctgaa acattgactc
     1801 gacaacctct ggagcgtaga tgagggcgta aagcagtata aagattaaga gcaatatcat
     1861 tgtgaggaat tgtcccgcct gtcatggcaa aaattttgcc gttgacatat tcatagcgaa
     1921 tatcctgttg gggttcccat tccagatatt cctggacggt catttttggg ggtttttgag
     1981 gaatagctac cattatcctt gaacacctgt gatgatttca gacttgcttc aatttagcca
     2041 aatgatcaaa tcaggaaaag cggctgcaag aattgtagtt aatacggtgg tttagcacag
     2101 aaaaataatt atgtggagct taatattttt agtggttttc tttgcctgga tattctggat
     2161 gaaaaatgct gcttcatctg ctagcaaaaa ttcccgtaat cgtcgtcaaa gaaattttcg
     2221 tcacagcaac agtgattaca ctagctcaga tatacactat tctggcagct atgactcagg
     2281 tagcagcagt tgtgacagta gtggatatgg cagcagtaat tgcgatagtg gtggttctga
     2341 cggcggtggc ggttgtgatg gtggaggatt ttaaattccg gtacgcatcc gcacactacc
     2401 cgcctgacaa tctcgcaacc aagctttcac tgcttgggca attacaccct tactactatc
     2461 cctggggggc gatactactt gttgtttttg aggataatca ccaatttggg taaacatcat
     2521 tactaaacgc cagccactgt tactttttgt caataacaac caatgaaatt gctgtgattc
     2581 aacgattttt ccagctatat attgccgttc tttagtagta aagaaaactt gctcaactcc
     2641 tgtgtcatta cttttctgct catcggcgtt gtatccacca gagttaatgg gtaggggctg
     2701 aaactctggt tttcctgcta gtagcacata actgtaaata tcactgctac gactgcgacg
     2761 gcgggcgcgt tgagtaacac gatttgcata acttggtaaa tcttgcaata gctgaatagt
     2821 taataattct aaactttgtt cagaacaagt agaacttaag ccatttttaa ctgcttgacg
     2881 ctgagttagt aaaacaggtg tattggcaaa tgctgagtta ttcatgctat ttgccgctac
     2941 tagccacaag ccgaaagcgc aaagccataa gccataattt ttgtttttga cttttgcctt
     3001 catcccactg tcgttaactc ctcaacaatc tttttccagg ctaactcagg ttcagcagcg
     3061 gcagtgatgg gacgaccaat tacgaggtaa tttgcacctg ctttgatagc ttgggcgggg
     3121 gtaagcgatc gcttttgatc tcccttctct gcccaactgg gacggacacc tggacaaacc
     3181 agcaaaaagt catctccaca agtttgtcgt aactgtgcga cctcctgggg tgaacaaaca
     3241 gccccattca acccgcattc ctgcgccatc agtgccattt ccaaagcata ttctggtaat
     3301 tccaggggaa tttttaaatc aaacgccagc tgtctggaag aaatactcgt cagtagggta
     3361 atggcaatta attgcggtgg tttaaccccg gcttgcattg ctcccacctg taccgcctca
     3421 gttgccgctt tcagggcatc tctgccagcc gtggcgtgaa tcgtcagtaa atccaccccg
     3481 taacttgcag cactacgaca agccccagcc acagtattgg ggatatcgtg aaacttcaaa
     3541 tctaaaaata tgcgtttttg ccgggatttt aaaacttcca ggattgtggg gccagaacta
     3601 gtaaataatt ctaaacccac tttccagaaa tttacttggg gcaattgatc tacaagagcg
     3661 atcgcacttt gtaaatcagg cacatccaaa ggcacaatta tttggtcatt agcccttcgg
     3721 ctacgctcag gataaatcat tggtcattag tgattattta ttcacaagtc ggacaaactt
     3781 atttttacca acttgcagca cacgtccgtg taattcacta gcctgctcaa aagtggtatc
     3841 aatatcaatc atgcgatcgc catctagacg caccccaccc tcttgaattt tccgtttacc
     3901 ttcccctgta cttttgcaca aaccagtcac attgagaaga tacgctaact tcaccggaaa
     3961 ctctgacacc tcagccagag aaaattcggg aacagcacct tccttaccgc cgctttttgc
     4021 cgcttcctta gcctcattag ctgctgtttc gccgttgtac tgtttcacca cttcccatgc
     4081 taaaagcatt tggcgatcgc ggggattttc tggcaatttt tccaaactga aatccgtcaa
     4141 cagttcaaaa tactgagaca gcaaattatc gggaacacct tgtaacttct gatatttttg
     4201 ggcagggtgt tctgacaacc ccacataatt accgagagac ttagacattt tttgcatccc
     4261 atctgtacca attaaaatcg gtaacagcaa cccaaattgg ggcttttgtc caaaatggcg
     4321 ttgcaaatct cgccccacag caatgttaaa cttttgatca gttcccccca actccacatc
     4381 tgcctcaaca gccacagaat catagccctg catcaatgga tataggaact catggatgaa
     4441 aataggattc tcttttttat aacgttcagc aaatccctct ttggctaaca tctgccccac
     4501 cgtcatcgta gaaagtaact ctagaatctt ccctaaatcc agatgggaaa gccattccga
     4561 gttataacgc acctccaacc gtcctggtgt gtcaaaatcc aaaatagggc gcacttgctc
     4621 aagatacgtt tgagcatttt gtgccacatc tgcctctgtt agctgacgac gcacctcaga
     4681 tttacctgta ggatcgccaa tacgagctgt aaaatcacca ataatgagaa ctgctgtatg
     4741 accagcatct tgaaacgctc gcagtttgcg tactggtatg ctatgaccaa gatgaatatc
     4801 agatcctgtc gggtcaattc ccaatttgat ccttaaaggt cggttcgtag ttaccaagcg
     4861 tttctctaaa ctttcagttt cactatcagc atcaattggt tggggaaaaa tttctactat
     4921 tccacgatgt agccaagaaa aattttgcgt catactcaga gattcgctat taactacgct
     4981 ttttactcta taagttaggt tggttatatt cactagcaat ttgtccgtac tttaatctac
     5041 agaattcata taattgccaa aaattaaccg ccaggcttca ttgaacgaat tacagttata
     5101 tttaccagtg aggaagtgag aacgccgtgt cgtcttctag gacttttaca aataagcagc
     5161 cacaacgtca ggcttcatca ggttttgagt ttttgaaagg agtaggccaa attaccggcg
     5221 ctactctgct gtcaataacc atgctggcaa gctctattgt agccggaggg ctggttggtc
     5281 tggctattag tttccgtaac ttgccagatg tgagacagct gcgtaacttt tttccctcgg
     5341 aaacaactta catttatgac attaatggca aactcttaac aagtcttcac ggtgaagcca
     5401 accgagaagt catggcctta gatagaattt ctccacatct gaaacgggca gtcctagcca
     5461 gcgaagatag tcatttttac gatcatcacg gaatcaatcc cagtggtgtc ggacgggctt
     5521 tgatcgttaa cttggcagca ggtagtgtgc gagaaggagg ctccaccatc accatgcagc
     5581 tggtgaaaaa tttgttttta tctcaaaaac gtgcctttac tcggaagtta gctgaaggag
     5641 tactggcaat tcggttagag caaattctcg gcaaagacca aattttagaa atgtacctca
     5701 atcaagttta ttggggtcat aataactatg gtgtacaaac agcagcacgc agctattttg
     5761 acaaatcagc agaaatctta accttggctg agtcagcaat gatggcgggt ttaatccaag
     5821 ccccagaaga atttagtccc tttgcgagta tggaactggc aaaacgcaaa caaagggaag
     5881 ttttgggacg gatgctggaa ttgaactgga tcagccagca agagtatgat gatgctctca
     5941 agcaagaact gaaattgggt cgcatcaggt cattccaagg aagtgcctta ccttatgtca
     6001 ccaatactgt gtctcaagaa ttagttaaaa aatttgggcg tgaggcgctg attaaaggtg
     6061 gaatgcgtgt gcaaaccact attgatgcta acttccaaac gatggcggaa aaaactgtca
     6121 gcaagtggag tagaacattg aggggtcaag ggttgcgtgg taatgaaatt gctctggtag
     6181 ccatcgaccc ccgcacgcat tttgttaagg cactagtagg cggtgtagat tctagagcta
     6241 gcgaattcaa ccgtgcaacc caagcgcagc gtcaaccagg ttctgccttt aaaccattgg
     6301 tatattatgc cgcctttgct actgggaaat atacaccaga tacagtagta caagatacac
     6361 cagtcagtta tcgagatggt agcggttggt atagtccgaa gaactacgat agtggctttc
     6421 aaggagcaat aacgattcgg tcagccctag cccagtctcg caatattccg gtaatcaagg
     6481 tgggtatgtc tatcggcatg aataaagtcg tagaagcttc ccgtaccttg ggaatcatga
     6541 gtccgatggc acctgtgact tctttgcccc tgggagctat cggcattaca ccgctagaac
     6601 tcgctagtgc ttacgcgact tttgccaatt atggctggca atcgccacca acagttatgg
     6661 ctcgtgtcac cgatagtagt ggtaatatct tgctagataa tacacccaaa ccccagttag
     6721 ttctggatca atgggcatcg gcagcaacta tcgatgtcat gcgttcagta gtcacttcgg
     6781 ggactggtaa aggtgcagat ataggtcgcc ccagtgctgg taagacaggc acaacttcat
     6841 ctgaaaggga tatttggtat gtgggtaccg taccacagtt aacaacagct gtctgggtcg
     6901 gtagagacga taacagacca ttatctagag gtgcaaccgg tggcggtatg gtggctccta
     6961 tctggaaaga ttttatgcag caagccctca aaggtgtacc ggcggaaaac tttaagcccc
     7021 cttctcagtt tcagcgcccc aaatcttaaa caaatcaaaa atcaaaaatc aaaaataaat
     7081 agggattttg gatgggcagt taatccaaaa tccctactat aaatttccaa ttcactattg
     7141 ctgttgttct agttcggttt tcatcctctg tagggtaaga tgcatttgct caaacatctg
     7201 ttgcggtgtc acaccaaatt gacctaactg agtcttgagt tgctgcacag tcatctgcgc
     7261 catgaaatcc tctgaaagct cgaatcgctt cataaagacg cgatagcgat ccatcataac
     7321 ttccattttc tcaataaaca gctttttgcc ctcacgatca aacttgccgt agttgttgcc
     7381 aagattgatc agtgtttgat aatcctcaaa aagatgtttt gcttcttgct gaactatatc
     7441 agagtcaaag aatcccattt tgcttatatt caactgagta ttgagactca gcagcttaat
     7501 atttttgcct ctatcattat cttagtctag ggaattcatc tagggaacaa gtttcggttt
     7561 aagtacggtt ttttaccgga atttcaacac ttgactgggg gagtggggag gagaagaggc
     7621 aggggtgcag ggagcagggg gcaggggggc aaagaatttt ggattttgga gaaagcgtta
     7681 gcgaagcgta cgcagcgagt gcgagtattt tagattgcag tctaatccaa aatctaaaat
     7741 ctaaaatcta aaattgattg actaatgaaa tccaacataa ttttctgatg tatagtgcct
     7801 aaaggtcgga tttcatcggc aattggggaa taacagttac cttggcgaat atctttaggt
     7861 gttaataatc ccatatccca accttcgttt aaaacaagtt ggtttaattc gactagcagt
     7921 ggtgcatgaa agacatgacg aacaacagca tcatttgcat aacaaccaaa ttccgaaaat
     7981 gatgggaggg tatagccgat ttcttcgata acttctcgct tgactgctac atctggcgtt
     8041 tcaccaagtt caagatgtcc accgaatagc ccccagtaac cagggtagat aatccctggg
     8101 atgttgtctc gcagttgcat gagaaacttg tcttcttggt aaagaattgc gatcgctaca
     8161 tgaactggtt gattagtcat gaatttttac tggtaatttc tcctgaaaat cttaactttc
     8221 ctctagataa acttccccaa actcttggtc agctaaggga atactcttgt agcgaacttt
     8281 acccttaatt accacttgcg ccccctcctt gagattgggt tgattagtaa tcacccaaat
     8341 tttaccagtg gagtcattaa tttgatatgc ccattgatta actaagggaa cttgcttttc
     8401 caccttacct tggacgtaaa cgatagtctc ctggtctgtc tctggtttaa tttcctgaat
     8461 cagggtgaca ttgctgccaa tgcttaagtt accagctttg aagctcggta ttgtcaagga
     8521 actacaactg caaagacccg caacaagtaa caaagtaatt ccctggcggt aaggaatcat
     8581 actgcaaagg tgaaattttt tggttggttg catcaagtta gttaccgtgc gtaaatttgg
     8641 ggagggttgc gggggatgat ttcccattac cctttatatt tcattccttc gcgttcagat
     8701 gaggcagttg atctgagaag ataaacaata taaatatagt cttgtggata gaaagacgct
     8761 aaggcactaa gcagcaacgc cttgatagtc aatagacaaa agttatttat gactgttgac
     8821 tctgctgcaa aagacagcaa atctagacta aaggcgcgtc ttgtaggaat tctaatggaa
     8881 acaaaaactg ccaaacttct cgatggtaaa gctttagctg acaaaattca tcaagaactt
     8941 tcagctatca ctacagaaac acaagcaaaa attgggcgat cgcctggttt agctgtatta
     9001 atggtggggg ataacccagc ctcagctgct tatgtccgca acaaagaaag agcctgcgct
     9061 aaagttggta ttgcttcttt tggacagcat tttcccacag aaaccaccca aggggaacta
     9121 gaagcagtca ttgctgcact caacgaagat gaacgtgtgg atggtattct cgtgcagtta
     9181 cctctaccta gccacttgga tgctgtcgcc ctgctgaata aaatagaccc agacaaagat
     9241 gctgatggac tgcatccagt caacttgggg cgattagtgc ggggagaacc tggtttacgc
     9301 agttgtaccc cagctggtgt gatgcggcta ttacaggaat atgaaatttc tttgcaggga
     9361 aaacacgctg tagtggtggg acgcagtatt ttagtaggca aaccaatggc cttgatgcta
     9421 ctggaagctg atgctactgt cacaattgct cactcgcgat cgcttgacct tggtacgatc
     9481 acgaagaatg ctgatctgat cattgcagct gtaggtcgcc caggattaat tacagcccag
     9541 atggtaaaat caggctccgt tgtggtagat gtggggatga atcgtgtaac agatgccagt
     9601 ggcaaaagtc gcttagtcgg cgatgttgac tgggaatcaa ctgctggtgt agcggaatat
     9661 atcactccag ttcctggtgg tgttggtccg atgacagttg ctattttatt gcaaaataca
     9721 gtcgccagct atttgaaaaa ggcgaagtag ttgtgagttg tgagttatga actctaaatt
     9781 attaacacct tacccctaac tcatcaccaa tagttcctta atgctacaaa ctcccaaatt
     9841 atctgtagaa tcaatcgaaa atcctcaagt ccctagattg tcaatccaaa atctaaaatc
     9901 taaaatctaa aattgtttga ctttttccgc gccacagcat cttaaaattg tgacggataa
     9961 gacaaacagc caacagccta aaattgaagg aatttgaaga atggtagcag ctgataactt
    10021 ccagaaaatg aaagaggaag ccacctttaa cctggtagcc tatctcaaag agcggcaaaa
    10081 gctttgtgaa actgctctgg atcaggctat tcccgtgatt tatccagaaa agatttatga
    10141 atcaatgcgc tactcgctat tagctggagg taagcgcata cgccccattc tctgcctagc
    10201 ggcttgtgaa atcatgggtg gcacaattga aatggccatg ccaacagcct gtgcgacaga
    10261 aatgatccat acaatgtcct taattcacga cgacctgcca gcaatggata atgatgatta
    10321 tcgtcggggc agactgacaa atcacaaagt ttatggggac aatatcgcca ttttggctgg
    10381 tgatggcttg ttggcttacg cttttgagtt tgttgccact caaactccgg aaaacgttcc
    10441 tagagaaaga gttatacaag taattgcccg tctcggcaaa gccttgggag ccgccggctt
    10501 agtcggcggt caagtggttg atttagactc agaaggtaaa tcagatattt ctctagaaac
    10561 cctgaatttt attcataacc acaaaacagc tgccctttta gaagccagtg ttgtttgtgg
    10621 aggcatgatt gccggggcat ctgcggaaga tgtccaacga ctttctcgct attctcaaaa
    10681 cattggtctg gcatttcaga tcatcgatga tattctggat atcactgcta cccaggaaca
    10741 attaggtaaa actgctggta aagacctcat agctaaaaaa gttacctatc ccagcctttg
    10801 gggacttgaa gaatcacgct ccaaagctca acagctagtg gaagcagctt gtaaggaatt
    10861 ggaaacattt ggcaaattgg cacagccact ccaagcgctg gctcacttta tcaccagtcg
    10921 caatcactag tacaagttgg cgtaaatcaa cagaccattc aaaatccatg aaaagccaat
    10981 tttataagct ttttgacttt tgacttttga cttttgactt ccgccttgcg gtactaggtc
    11041 aatttgggat ttgggatatt gggttgcatt gaaatgtttt ctcagaaaat aattgctgct
    11101 aaatttacta accgaaccaa aacaccatgc aggacatagg caacatttta gataaccggg
    11161 tgctgttggt ggctctggtc gcttgtttaa ttgctcaagg attgaagctt gtagttgagg
    11221 tagtcaaaaa tcgcaaactg aatgtccgtg ttttagtgac aactggaggt atgcccagcg
    11281 cccattcagc tttggttaca gctcttgcag ctggtgtagg gcaaagtctt ggttgggcat
    11341 cgcctgagtt tgctttggct actgtttttg cgatcattgt catgtatgat gcagccggag
    11401 tccgccaagc tgctggcaag caagctcgga ttctcaatca aatgattgat gaattattcc
    11461 acgaaaaacc agactttagc caagaccgtc tcaaggaatt actgggacat acaccagtgc
    11521 aggtgatagt tggttcagct ttgggcatca ccatctattg gttagctcgc tctgcttact
    11581 agtaccgtaa ttcgtaattc gtaattcgta attcgtaatt cgtaattccg ataccatata
    11641 cgttttattg atttcaaatg gtctgtttat ttacgctgac ttgtacaagt ttataaacgc
    11701 acagatgagc gcagtaacat taccttactt ccatccacta gaacggcaaa aaaaccgcgc
    11761 tcggtaagct tttgcagtgc gttgtatgct tcttgttggt tgccagtata aactgccaat
    11821 aagtaagggc gttgtccgta agaagcaaaa cctatgttac ctcccactac ttgatgtatg
    11881 ctatttgcca gttctggttt gttaaaatac tctaccaata cagcataacc atctcctaga
    11941 acttggggat taaagctgat tgtctgaggt agatttggtg tttgtgtgac attagctgct
    12001 gccggtcttg tagtgatggt ggcagataaa ccgacaatac tatttacata tgtagcccaa
    12061 cgattggcat catcaattct gttaaacccc cctatccgcg ttactgtatc agaaagatat
    12121 tgacaagttg tcgcttgaat ttgatttggc aaggcactaa gtagctgttt ctgactattt
    12181 gctgtgggac taactaccag caaaagatac tctccagggc ggggaggttg acaaacggga
    12241 acattttgtt gggcagtgac agaagtcatg ctacctatca agcctgctgc tgcaagtgct
    12301 aatgcactag ataaattatc aaatttctgc acaaaattgg gttgcataaa ctggattttt
    12361 tccaaagatt ttcaaaatgc cttttctgtt ccccgacttt cagggcaggt tttttaccta
    12421 ccccaaattg ttctagcttc gttttgaggg tttgtagtca gcactttagt gcttatacca
    12481 atttcagagg aatgaaggcc gaagggcttg ccgcaggcta ccgcattctc ttacaaaacg
    12541 cgttcgcgta gcgtcccgta gggaaggaga aggacgcaaa gaaagccaga aattcggcac
    12601 ggttcctcac aaagaaatgg taggagaaga caggactgaa atcctgacta cgaacttgtt
    12661 aagacactga gctgagggaa gctaaaggat ctgagatagt ctcagaagga gcctgaaatt
    12721 ctcctgtaat cacatactct aatcgcagtt tgagccaggt aataaattgg gcattggtag
    12781 aaataatggc ggcggctggt cgaggacact tcgcctttac ttctgccatt tcaggcgatt
    12841 ctaaaaaagc tggctggttc accaaccaaa aatcaatttc tttttcttgt tcatggtagt
    12901 gacgagtgcg ttctttcaga acttctgcgg ttggttcttc ttgaatcagg aatttgtgac
    12961 ttgccaaagc gtaatagtat gttttcattt ttaaaccttt gcttgctatt caataattta
    13021 agggtacagt gctatatcct atacccctaa aaaataatta aaccagaatt acttcatcaa
    13081 agcactgaaa ggacaagcac tggtttttgc aacgcccgtt ctgggttttt cttgccaatg
    13141 ccacaattgt gagaaaaaat tccaaaaatt tggttttttg tgcttttgtt caccagtttc
    13201 ttgttgtcct tttgctgtca gcttatctaa gaacttggtg ttgtcatagt agtgttccaa
    13261 agaaaggatt ttcaagtcat cggtgacgtg ggcaacgctc atgccgataa cttctattgt
    13321 ctctcctgtg ggtgcgttgt ctttgtatgc gcctttaaaa tgtccccaat gccgccactt
    13381 aaaggcaacg gtgggtgggg ctgagaacac ctctaggact tcccaggtaa atccttcggg
    13441 gaaggctgta tggaagaggt ttgtggatgt ttcaaagttt tcttcagcag ctttgtagtg
    13501 tttggtgtta ccaattagga gtttgtaagt tcctgactcg actaaatctg atactgtgta
    13561 gcctggacct ccattggtac tcatgcggaa cttttcgttg acaaccgata tccactgttg
    13621 ggggttggtt ttaaagttcg cttccacatc gaaggttctc actaagtttt ggactatggc
    13681 ttctagtgaa ccttctggat gattgcgtgt gctttctctg gcgatatttt cgttggaacg
    13741 agtatagtct ggaaatttgc catagcgcca ttcgatatcc gtactctgtt ctagtacttt
    13801 atctctgtgc tgtacccaaa gcggtaggtt gttagactct gttgaggtca tagcagtttt
    13861 tgctgaaaaa tttaactcca aatttctgga tttcgcagtt acaacccctc tttttcagtt
    13921 acagcacttc ccagtgttat gaggtacaag aaccccaccc ccaaccccct ccccgcaagc
    13981 gatgaggggg ctaagagtac ttcatataat aattggaaat cgctgtatca gttgttagtt
    14041 atcagttatc gggctagaaa attgtgataa ctgttcactg taattgcttg tttcatttcg
    14101 cggacggctc tttcgattcc tactaatgcg gctcgactga taatggtatg accaatgttc
    14161 agttcttcca ttcctggtag tgcagccacc ggataaacgt tccagtaggt gagtccatga
    14221 cctgcgttga tgcgtaagcc tgcttttatt gcttgttcac atccttgagc taataccgct
    14281 aattcttgct ggcgatgagt ttcgtcttta gcctcagcgt actgcccggt gtgcagttca
    14341 ataaattgcg ctttcacctt gacagatgct tcaatttgtg ctggctgtgc gtcgataaat
    14401 aaactaacgg gaataccaac gctctgcaat ttatctacta tctcacctat tctagcaatt
    14461 tgtccgacaa tatctaatcc gccttctgtt gtgacttctt cgcgcttttc ggggactaag
    14521 gtcacgtaat cgggtttgat atcgagggcg atcgctaaca tttcgtctgt agcggccatt
    14581 tctaaattga gatgcgatcg cactgtctgc cgcaagagta gcacatctct gtcttgaata
    14641 tgtcgccgat cttcccgtag atgcactgta atcccatctg cacccgctaa ttctgctagt
    14701 accgccgccg ctacggggtc tggttccact gtccgccgcg cttggcgaat ggtagcgatg
    14761 tggtcaatgt taactcccag tgtaggcacc cttgtatctc cctatctata atccctaagt
    14821 cttgatttta aaggatttta gcggctgctt gagcaaattt gagtcaatgt aattatagtg
    14881 gtgcgatcgc ctttggcggg gcgtagtcca tcgcctaaat tacaaagccg gatttagaat
    14941 aatatttaca cccactcttt gaggtcgata tgcttttaga actacaacag attatcgtca
    15001 aaccaggaca agaaatgttg ctaaaagata ttagttggca gcagttagag aatattttgg
    15061 cagaaatggg agaaaaacgg gctgcacgca tttcttatag tgatggttgg ctagaaatta
    15121 tggttccttt acctgaacac gaaaaagata aagaaattgt tggggagttg gtaagaattt
    15181 tattagacta cctccaaatt gattttgaac cttttggttc caccacacta aaaaatgaac
    15241 aaatgcggca agcagtggaa ccagatactt gtttttatat tcaaaatcaa gctgctgtaa
    15301 ttgggagaaa tcgtcttgat ttaactgtag atccaccacc agatttagca attgaaattg
    15361 atattacttc ccggactcga tttgataatt atgaaatttt gggagttcct gaactttggc
    15421 gatatacaaa agaaggttta gaaatttctg taatacagga aggaaagtat atcaaagtgc
    15481 catctagccc taattttcct gatatcccca ttgtggaatt aattaatgag tatgttcagc
    15541 aatgtttaac tattggcaga agtcaagcta tacgtaattt tagaacttgg ctcaacagta
    15601 atttataata aatttttatt tatacatctt aattacaaat aaactaattc aaggattaat
    15661 ccgcacaaac tcatacttat caatgcctga ttttttttga attttgatta atacaaaatc
    15721 acccttgcga tcgcccgatg gttcaaattt gatgtttcca actgcaccac catcagcaga
    15781 aaaatttgag ttgcgtagca cctgttgcaa ctcagaacgg gtgttacttt gttgtaagcc
    15841 tttgataatt gctttagtcg cgtcataagc tgtagccgtt cgccaattga caattccacc
    15901 ccaaaggttt agagcattgt ttgcaaaggg attgtttgga aatgcctgtg gatgccaagc
    15961 tgcggtcagt accatgccat taacatcggc ttttcctttt tctaaggttt cgttagtgta
    16021 catagtaggg ctgctgaata tcggtagccc tctttgatta gcagcttttg caagctttat
    16081 ggcattagaa attctatcta tatgtggagc taagaacaag gcatttgctc cactattaat
    16141 agcttcagaa attttgacct cggcattcaa gttatcatct gacaaatcac aatgtgtatt
    16201 attaatcgtg gcacgagcct ctacaactgc tgtaacaaag tgatccctaa cagaatcatt
    16261 atctaaattt ctgaaatcac gacaaatagc aatgttactt gtatcaactg ttgtgatgat
    16321 atagttagcg agtttaactg ctgataaacg aattctggga atagcacgaa atatatatgt
    16381 gccagcatta gaaaagccgt cggaaaagcc tgtcggagca atcatgacta atcctccaag
    16441 ttcatacttt ggcgcagcac gcaaggaagc atcgctagtg ttatgtccta ctacagctag
    16501 gatgttatta tctttgacaa attgagaagc gattctttcg gattgaactg gatcattatt
    16561 atcgttagca atttctacga gtaaaagttt accttgaata ccgttattat tgttaacctc
    16621 attttgtgct tgtgctacac cacgcagtag ctcttgtgca acatctggat tactaccaat
    16681 gggtacactg acggctattt tcagcctttg tgtttgctga agcgctttgg cgttatttaa
    16741 ataaattaac gcttccgggt cactccgatt agtccgatta gcttggcggt ataaatttaa
    16801 cttattaata gcagtctgac aatcaccctt ggccaatgct ttaactccag cctgtttatc
    16861 tggatttgta ttttgtgtca ataaaatttc ttcacctaca ctcattttat cactgaaagt
    16921 atatgtatct acagcacaag atttaggtac agatggacgt aaaaacatag caaatacagt
    16981 gccgccaata attgttccaa taataattcc caatcctgta ttcttattca agatattgct
    17041 atttagggaa cttgcaatat ctgaagatac tggagtttta ttagtttgtt gtttagcaat
    17101 tataggagct tcaattaggg cgatcgcttc atcggttagt cctaatactt gttgaaaacg
    17161 tttcaagtca gtgatagctt tatcactgag aggaaatttc aattcaattt ctttacctaa
    17221 agcctgctca taccgagaca atttctgttg ataaattttg aaaggttcta aaacttgatt
    17281 ttcaattccc ttagcttcct cagttgttag ttgtagctta tttcttagct cctctaatgc
    17341 agagcgacct gtagaagaaa tttcaccgtt accaccttct acccaatact caacttctac
    17401 acgatattgt aaatgtgggt gatcatttgg tgctttggca agattaattt tataaccctc
    17461 tttaatagca tatatttgcg gtttcattgc tggcgatgct tcttgcactt ttctagtagc
    17521 atattcatgc aattcatcaa cacttatcca accatcttta tctttatctg ctacaccagt
    17581 tcccaagcct tccactacat agcgggtata aattgaggta tctgtccctg tatcttcaaa
    17641 agaatattcg gttgaagtcg aagatgtcag aattgcccgt ccttctccgc ctaattgatt
    17701 cttgacatcc acaaaaccat tatcttttgc tgacattccc tccgcaaacg cgccactaaa
    17761 gcaacaatca agaatcacta cctcccgttt ggagcggcta ttactcatga catcatgcac
    17821 aaagctagct ggtactgttg tggcttgaag cagtaagccg ttgtcagttt tacgggtgtt
    17881 acgagtggca aaatacagat gaccacgttc gtctttgata ccgtgaccag aaaaaaatag
    17941 cagtatcaag tcatcttttt gacgaccatt gccattaata cccttaaata aaatttctat
    18001 ggcttctgcc atttcttgtc tttgaggatt aaccagcttt tctacatcaa aattgccaat
    18061 ttctgggtgc tgtaaaactc gctccattgc ctccacatct tttactgctg ctggtaatgg
    18121 gggaagacca ccttcatatt cactgactcc gattagcagt gcaaatttcg ccattttgcg
    18181 atttttcctc tgtgatttaa tacctcagtt acctgcaata aacttttgcg cttgttcaat
    18241 agcagtgatt aattcttgac tactactagc cttgattttc agttttttac cgttagcttc
    18301 gacttccaat tcaatggttt tgttaccgag gcgatcgcct agaaatccca gcaatttctt
    18361 agtattgcca atactgactt cagcccgtaa aacccccagc agaaaaccac caaccggctt
    18421 gctggcttca ggtatttctg taactgctac gagtcctgcg ctttctacat ctaactcttt
    18481 tatctctcgc aagagattgt gcgtttcccg ttcttgttcc tctgcatcta agtcaggatt
    18541 ggcaagagtg atcgtgagtg tgacattaga ttgagaactc atattgtata tttttagatt
    18601 ttctagcagt gaatagtcta gtatattttc tgagtatact tgtataacat cctaatttat
    18661 taactaattt atggtaaatt ctgtaatatt ttgacaaaac ttagccaaaa atctgtagag
    18721 atgcgatacg ccctaacttg aagcactggt ataaaagcgc aaagcaaacc gccaaaatac
    18781 actggaaacc cagaacagga ctatagctaa aactccagca cctatagacc aactaatttg
    18841 accccgaccc agcatcgctt ctgctggtat agttgttaaa aatgccacag ggactacaaa
    18901 ggtgaagaaa aagcggtaag cggtgggata agctaccata ggatatctgc cagcttctaa
    18961 caaaccccgt aaaacttcag tggcattgta tatttttaca aaccaaatgc tagttgcacc
    19021 cagcataaac cacaaactat aaagaattac caagccgaat aacaatggca ctgcactcat
    19081 caggtaatta ttgattccta aacctaagcg gttacctgca tagccaatga caatactgcc
    19141 aaaaactaaa tctggtactc cccaaggtga caaggtatga gtggaaagcc aaaactgact
    19201 gcggataggt ttgaggagga caaaatctaa tgtcccttcc tgaacatggc gaacaatgcg
    19261 atttaggttc ggcgcgagaa aggtagctgc aaagccttgt aacaacgtga aaattcccaa
    19321 aaccaacaaa gctgcaaacc atgaccagcc cggaaaggtg tagtcagtac ggtaaaataa
    19381 gaataatcca aaaagactgc cggcgagatt acccaaactg ctgagggtag ctatgagaaa
    19441 attgaggcga tactccatct cagctgcgat cgcggtactc caaaatatcc ctaatagttg
    19501 ccaatatctg ctcattttgc acccttaacc tcatatattg ccagcatagc taatcattgg
    19561 caatcttggc cagtggatga actattcaac ctaaaatgaa attatcgtgc ataaattaaa
    19621 tttcccagat taaatgatta aactcgacca gtttttaaag tttatgggtg taacctcaac
    19681 tggaggacaa gccaaactga taattcttga tggtggtgtc aaagtcaatg gtacagttga
    19741 aacccgacgc ggacgaaaat tagtattagg cgacaaagta acagtagaag ggcaaacttt
    19801 cgaggtcgaa ctataatgta tccctttcct gcaaaaatct gtccttaaaa ccctacccga
    19861 cctgtaatat cgccaaactg cccctttcca ctcacgggta gggttcgggg tatgatgctt
    19921 aaggcatcga acttgatata aattttttca tataatcact aattactttt tatttatttt
    19981 taaatttcaa aatcaggtaa tcgactgcga tatttgtgcc aaaacgtgac tagcttaggg
    20041 ttaaaaaact aaataggaaa gttaattacc gcctttaggg ttagcctgtc atcagtgtgt
    20101 tgtagaaact cgacaacttt tggttgtatg gagtggttga acccttgatt tgctggcatt
    20161 tttgtcaaga atatgctcat ttgaatacat tctggattta gcaatttatt gatgctttat
    20221 atcttgagtt aggcgaagaa attgccctaa ttcagatgga tctagcacgc gttcatgtaa
    20281 cgaataaatt tcgctgaaca gagaatttaa ttatgatctg tcaacccgca catagtccag
    20341 agatcaattg cattgaacga gtttggtaag caggaataaa ccaaactata ttacaactcg
    20401 taaatactcc tgaaaccctc accaatgact aatgacaaag gacaaatgac gaccctagcc
    20461 agttaacttt atttacgccg acatacttaa tttattcaat accaagttca aggcgaagtt
    20521 ttgacaacac ttgaataatt acgagagcgc tgacaagaag ggaactgaaa aatcacgcca
    20581 gaataaatct gctggttttt atctgataat ttcattctgg aagccctatt ctaggaagct
    20641 gaatcttaaa ttggtattag catattctga ttagtataaa aactctattt ggtagtatta
    20701 ttttaaagtt ggtattgttt ttgcgaaaag atttaaactt aaaacttttt atggttaata
    20761 caggtcggga gccattacct ttacacgaac ttatttccca gatattaaca ccggaatctt
    20821 ccgttcagaa aggaagggga ctgctatcgg gattgggtag tatgcaagca ctcaatcagc
    20881 gccttgttaa tcaaccctta cccgatttca tcaacgcgag tttgcgggga
//
