LOCUS       NZ_JADEWH010000004     48254 bp    DNA     linear   CON 23-DEC-2023
DEFINITION  Nodularia sp. LEGE 06071 N071000004, whole genome shotgun sequence.
ACCESSION   NZ_JADEWH010000004
VERSION     NZ_JADEWH010000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nodularia sp. LEGE 06071
  ORGANISM  Nodularia sp. LEGE 06071
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales;
            Aphanizomenonaceae; Nodularia.
REFERENCE   1  (bases 1 to 409477)
  AUTHORS   Castelo-Branco,R., Eusebio,N., Adriana,R., Vieira,A., Brugerolle De
            Fraissinette,N., Rezende De Castro,R., Schneider,M.P.,
            Vasconcelos,V. and Leao,P.N.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-OCT-2020) Cyanobacterial Natural Products, CIIMAR,
            Terminal de Cruzeiros do Porto de Leixoes, Matosinhos 4450-208,
            Portugal
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2016
            Assembly Method                   :: SPAdes v. nov/18
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 30x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 12/23/2023 19:29:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,867
            CDSs (total)                      :: 4,805
            Genes (coding)                    :: 4,703
            CDSs (with protein)               :: 4,703
            Genes (RNA)                       :: 62
            rRNAs                             :: 6, 7, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 3, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 4 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 22 of 102
            Pseudo Genes (incomplete)         :: 84 of 102
            Pseudo Genes (internal stop)      :: 12 of 102
            Pseudo Genes (multiple problems)  :: 15 of 102
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:23:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 358686
            Orig. end                         :: 406940
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JADEWH010000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..48254
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="True"
                     /product="mycosporine"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="(DHQ_synthase and Methyltransf_3 and ATP-grasp_3)"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..48254
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(DHQ_synthase and Methyltransf_3 and
                     ATP-grasp_3)"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="neighbouring"
                     /product="mycosporine"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..44799
                     /SMILES=""
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(DHQ_synthase and Methyltransf_3 and
                     ATP-grasp_3)"
                     /kind="single"
                     /product="mycosporine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..44799
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:24799](-)"
                     /cutoff="10000"
                     /detection_rule="(DHQ_synthase and Methyltransf_3 and
                     ATP-grasp_3)"
                     /neighbourhood="20000"
                     /product="mycosporine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..24799)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(DHQ_synthase and Methyltransf_3 and
                     ATP-grasp_3)"
                     /neighbourhood="20000"
                     /product="mycosporine"
                     /protocluster_number="1"
     misc_feature    complement(109..122)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.06"
                     /tool="antismash"
     misc_feature    163..180
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 18.62"
                     /tool="antismash"
     gene            168..1238
                     /locus_tag="IQ233_RS09845"
                     /old_locus_tag="IQ233_09845"
     CDS             168..1238
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (87-216). E-value:
                     4.3e-09. Score: 27.8. Matches aSDomain:
                     nrpspksdomains_IQ233_RS09845_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017804047.1"
                     /locus_tag="IQ233_RS09845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09845"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_193998694.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.1e-06, bitscore:
                     22.4, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRILITGICGFVGSTLAKALQEYFPEYQIVGIDNFSRSGSWLNKA
                     TLQQRGIEVIHSDIRHSSDVDALPSADWVIDAAANPSVLAGVDGKTSSLQLVQHNLLGT
                     INLLEYCKRYQAGFILLSTSRVYSIPGLSKLQVAEANGAFYPVPEQIFPVGISTMGVAE
                     NYSTNPPVSLYGSTKVASEHLALEYGATFEFPVWINRCGVMAGAGQFGHPGQGIFAFWI
                     HSFREQRSLKYIGFGGKGYQVRDCLHPQDLINLLQKQFAEPLNTNKPRVVNVSGGVKNS
                     MSLRQLTQWCADKFGSNEVLETNIERTFDIPWMVLDASLSEKVWGWTPQIGIEKVLEEI
                     AIFASEQPDWCRLSAT"
     aSDomain        429..815
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IQ233_RS09845_NAD_binding_4.1"
                     /evalue="4.30E-09"
                     /label="IQ233_RS09845_NAD_binding_4.1"
                     /locus_tag="IQ233_RS09845"
                     /protein_end="216"
                     /protein_start="87"
                     /score="27.8"
                     /tool="antismash"
                     /translation="DGKTSSLQLVQHNLLGTINLLEYCKRYQAGFILLSTSRVYSIPGL
                     SKLQVAEANGAFYPVPEQIFPVGISTMGVAENYSTNPPVSLYGSTKVASEHLALEYGAT
                     FEFPVWINRCGVMAGAGQFGHPGQG"
     gene            1235..2431
                     /locus_tag="IQ233_RS09850"
                     /old_locus_tag="IQ233_09850"
     CDS             1235..2431
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IQ233_RS09850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IQ233_09850"
                     /product="glycosyltransferase"
                     /protein_id="WP_193998695.1"
                     /transl_table=11
                     /translation="MTYKILYISAVIPDTTSGGRFAMYRHLIIKKDFEVAVASTNFVKL
                     PIKQQLSIRRNRLIERLRRTRLCRLIYNLEYLLNWINIPGSLLKFADDFKPDVIVSVVD
                     DWHLGLAFQLAHQLKVPLIVNFQDLFCLSQFVPLSARPYPVITSWLIQRYHQVNELANQ
                     VFYTSEGMKEWFGVDDQGNVLYPVGDFDVQVSIEQRANSQDKVKIIYAGNCYGAYGRML
                     LRLAESVQKHQHIHLQIFAAGNDWTPEKLQEMTEAGIYQGFKPFDELKDELKQADAFLT
                     VMSFEKSEEIFMRTSFTTKWLDYVPYAKPVFVWTPEYSTACGFAKKYQSGIPVIHDDPE
                     VLLKVISETASNSMAWSSACEGSRRVAETVLNAEQIHHLFVERVTNVCQECNTKNLQD"
     gene            2451..3617
                     /locus_tag="IQ233_RS09855"
                     /old_locus_tag="IQ233_09855"
     CDS             2451..3617
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017804045.1"
                     /locus_tag="IQ233_RS09855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09855"
                     /product="glycosyltransferase"
                     /protein_id="WP_322744529.1"
                     /transl_table=11
                     /translation="MNKRKIIVISSISPQPTSAGQILLYRHLNQATGWDVDIVPNPYEI
                     KTDRWQTKLIKRLEYTRFHPWGHDFQVIDQGMVWDNTLLNSHQRVFNSQTGDKTIVLTI
                     SHGDGCWAAQRFAHHYQLPLVTIFHDWWPDIPTLHKPFRQLLERRFEQLYQQSNLALCV
                     SEGMKNALGSHSNSTVLYPIPALLKEEIITQYQPENDQISSPLQVVYFGNLHEYGPILA
                     QLLEVTKDNAKIQVQVRGSNPNWSADFRSEMRDRNLWLDFAPREELNHWLASADVFLVT
                     MSFDPALRRRMETSFPSKLPEYAQFGKPLVIWGPNYCSAIRWGSEGDRALCITDENPQV
                     LVSALEKIKGFPEQQEYYAKQSRIAAQTEFNPSIIQNQFVESLQSLIK"
     gene            3642..4892
                     /locus_tag="IQ233_RS09860"
                     /old_locus_tag="IQ233_09860"
     CDS             3642..4892
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012744.3"
                     /locus_tag="IQ233_RS09860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09860"
                     /product="glycosyltransferase"
                     /protein_id="WP_193998697.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 3.4e-30,
                     bitscore: 99.4, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSSCTIKHFSTELSGGSGIAAQRLHKALLEKSISSELLFRKGST
                     SLPHSISDRRNSSLPWRDLDSITISKEWNRSVNDRSLFTNPQWIYKTQLKDFGKLPEII
                     NLHWISRWIDQPSFFDSIPPDIPIVWSLHDMNPITGGCHHALDCEKFATHCCDCPNLKN
                     SGKHDQASKNFALKAKLYQHLNLHFVGNSTWTTLQAQKSQLGKYARSIRTIPLGIDIKD
                     YQPIDRSIAKAALRVNPDDLAIAFACADLSDKNKNLPILLEAIAQLSKHHSITLILFGS
                     GQIPELNSQITTVILGHLSSPQLQSLAYSAADIFVMPSQIESFGLTALESMACGTPVLA
                     FRTGGIPDLVIHGETGWLADDIGSIESLYEGLHWMLQHPQERSHLGKAARQRVEREFTD
                     DIMANRYINLYQELISP"
     gene            4889..5989
                     /locus_tag="IQ233_RS09865"
                     /old_locus_tag="IQ233_09865"
     CDS             4889..5989
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008417 - fucosyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006197670.1"
                     /locus_tag="IQ233_RS09865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09865"
                     /product="glycosyltransferase family 10"
                     /protein_id="WP_193998698.1"
                     /transl_table=11
                     /translation="MKRVLIRPTFQDWCENKLFSDGTSFASVYQEAFSLWKQQAAKIGF
                     QLDTWDQAPLETADIFWFLDLPPSRQEFTRIRAQLQPKTPIVLQILESPFLAIHAFNNA
                     NTQDFDAVLSYEYIETIKQKERHFHYHLPNQLRQPQTNLSYSERKGLLLINSNRVAGFF
                     GMRQVGFSGIPGLGKFLAGWHCSLSMFSEALSGELYSERRKLARIAELISLNFLDIYGR
                     GWNGEQISWCPLYENRSYNSWRGIPTISKWDLCEQYRFVLSFENFKGRRGYISEKIFDA
                     MFAGSVPVYLGDDRITDYVPSDAFVDARNFDNYPDLLKYLITCPEAAWLDMRQAGQAFI
                     KSDEFQCFNSLQFAEIATQILKKVTV"
     gene            5991..6680
                     /locus_tag="IQ233_RS09870"
                     /old_locus_tag="IQ233_09870"
     CDS             5991..6680
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156: Chloramphenicol acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006197671.1"
                     /locus_tag="IQ233_RS09870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09870"
                     /product="acyltransferase"
                     /protein_id="WP_275973769.1"
                     /transl_table=11
                     /translation="MKLQNVKDRLRNSKFLRILYAKLLSRGNSFNLKGNNNILDTAGAI
                     LKKCSLQVVGNNNLISIDVGCYLEGVKIFLQGDNLKLKIGRSVFIGQGSVLWMENSDGL
                     IEIGEFTSIEKVAIAVAEGKKIIIGKDCLVSYEVDIRCSDSHAIFDQEKKCRINPAANI
                     EIGNHVWLGAKCLILKGVTIGDGSIIGAGSVVTKSVEPNSVAAGNPAKVVRSDIVWTRS
                     RSDSFPE"
     gene            6816..7763
                     /locus_tag="IQ233_RS09875"
                     /old_locus_tag="IQ233_09875"
     CDS             6816..7763
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IQ233_RS09875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IQ233_09875"
                     /product="hypothetical protein"
                     /protein_id="WP_193998699.1"
                     /transl_table=11
                     /translation="MTTNFGIVTACWKGDYFLVKATCASIRHFLGDVPICVIVDGDFSI
                     QELENLYGVQPLYLSQLSNPELRRRCPGSSRAKLAAIWEGPFEHFLYLDSDAIVWGNLL
                     EKFDLTTTDFVVMRPPLYGCLPKHEVSRWFFNVDTLLEIDPTFEWQNQPYFCAGAFAAK
                     RNCFDLQEYLRLEALADKYPELFKFWDQGIVNYMVFSANQAGLLKYKVVDIQVVTADHS
                     KSTLEEQYPCSIYKTPQNVDKTTIIHFCGNKPFIHKRKSFSKPFTTFRLLHYQKLMGDN
                     ISGKIKSIFQLFCEEFELLTNKAKSKFKRIINSQ"
     gene            7774..8517
                     /locus_tag="IQ233_RS09880"
                     /old_locus_tag="IQ233_09880"
     CDS             7774..8517
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR01444.1"
                     /locus_tag="IQ233_RS09880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09880"
                     /product="FkbM family methyltransferase"
                     /protein_id="WP_193998700.1"
                     /transl_table=11
                     /translation="MKTLFKSTLNYLEKIYHFSSFRGHSFWNIPIDSNSVVVDLGANLC
                     DFSSEVKKRFECTVFPVEPNATLNPNDSYFLDSVDRLAITNCNGEVDFTISENSEASSL
                     YSNLANLFGSTKTIKVRGMSLNEYLKLKEIEGSLSLLKVDIEGGEIDLLSKIPLKELEL
                     IDQMTVEFHSFLDPSLELEVIAIIDRISKSGFWVINCNHPYYDDVLFFNKKLFKKYHFK
                     CLDIFIMKIVYIIRGKMHKLIGTHK"
     misc_feature    8521..8533
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 21.58"
                     /tool="antismash"
     gene            8567..9421
                     /locus_tag="IQ233_RS09885"
                     /old_locus_tag="IQ233_09885"
     CDS             8567..9421
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006197673.1"
                     /locus_tag="IQ233_RS09885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09885"
                     /product="glycosyltransferase"
                     /protein_id="WP_193998701.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 7.6e-12,
                     bitscore: 39.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSISALIPTYKRVDKLENCLQKILSCDPLPSEIIIHIDAGDSET
                     EPFLIAQNYPLVTWISSNTTQGPGGGRNKLIKQAKFPIIAGFDDDSWPLDKNYFAIATE
                     LFSLYPQASVITAQEVRPSTFPKQLNNFIKEVNCFQNCACLMRREAFLQTRGYLPLRYA
                     YGMEEADVALQLLDCGWQILESFNLCVFHDTQLEHHNHPSVNAAHIANTALLAYLRYPI
                     TYWPLGIVQVFNRMRYAASVGRWKGISQGLSQIPHLLSCYANQRDPVQVHTLELSRKLA
                     SKS"
     gene            9418..10629
                     /locus_tag="IQ233_RS09890"
                     /old_locus_tag="IQ233_09890"
     CDS             9418..10629
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016860710.1"
                     /locus_tag="IQ233_RS09890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09890"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_193998702.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 4.2e-26,
                     bitscore: 86.1, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKNSRNWICCQIGAREHYAIPRALHQHEKLAHLITDAWVTPVSP
                     LKILTQSGLRERFHPALAKVQVHAFNSFLIRFEISQKLQKRFGWETIIARNNWFQQQAI
                     KKLTQLTEKFTTPPILFSYSYAALELFKFAKKQGWYTVLGQIDPGLWEEQIVIQESEKH
                     PQYHKNWQPALREYWQIWQEECNLADAIVVNSHWSSQLLEKTGIEVKKIHIIPLVYTPP
                     KIANKFIRTYPESFSQKRPLRVLFLGQVILRKGIASVLESIKSLEGYPIEFWIVGSKEL
                     QIPSYFENHPQVHWVGRVNRSETAKYYQLADVFLFPTLSDGFGLTQLEAQAWQLPIIAS
                     RNCGEVVVDGVNGWLLPEVSNVAIANILKLCLHDPENLTALSKNCQITNKFTLETLTQH
                     LLKF"
     gene            10632..11978
                     /locus_tag="IQ233_RS09895"
                     /old_locus_tag="IQ233_09895"
     CDS             10632..11978
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006197675.1"
                     /locus_tag="IQ233_RS09895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09895"
                     /product="hypothetical protein"
                     /protein_id="WP_193998703.1"
                     /transl_table=11
                     /translation="MPPNLEIPFSYYIAAALLLFFFIEAASKIHRSWAIPALMTYLTTG
                     MWYFTEVFYTPERLTIFNSSILEQAYYQICIFLILFRWLLPSFTRTIGKYSSKVNAFNW
                     FTLNPHRLLQILLVMWILLFIYGISRLDWNFFQALLPQGGRWSPKLWNRGAVGGGTEFI
                     VSAAGYTYTLICAMFGVLIFFQRQPQAKVINLVMIIISWPAFYLSGTRNSFLAVAMPAY
                     MTYLLTSRHKWWVKVALSAGLFVLINYLMLIAISFRNTGIDAYFEGAATLNTESKHEGL
                     NMAEELFYINKFYEQGELTLQYGMDYLAESLNLIPRFIFPDKPLIGHEYNLLRNPSSGI
                     QATISAGFIGRGVLNFGPWFGPIVPAILMGLWSAFLARLWNQRSSILRLSLFLVGLGIT
                     PNLGRDITLLVLWPILFGYVIVRYLERLERRRMLRYATQYHYYKHELRS"
     gene            11962..13110
                     /locus_tag="IQ233_RS09900"
                     /old_locus_tag="IQ233_09900"
     CDS             11962..13110
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006197676.1"
                     /locus_tag="IQ233_RS09900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09900"
                     /product="glycosyltransferase"
                     /protein_id="WP_193998704.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.6e-32,
                     bitscore: 107.0, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNCAPNNLQIAILFANYGPYHIARVASAYHACKSSGCNVFGIELA
                     RSEVEYPWEIQLDKFPGQIHSVIDDVPLEKVKFSHLFGKLISLLNRTCPDVIAISGYAR
                     PSMLVTLLWCLWHGKSAILLSETTENDEPRSWWKEKIKKLLITRYKAALVGGLPHKRYL
                     IKLGMPSEAIFLGYDVVGNDVFHPNQIKSLSCPLAQPFFLAINRFVSKKNLPFLLSAYA
                     KYRQTAGTDPWDLVLCGDGELRLLIEEEITNHKMQNYVHLPGFLQQDQLLPYFAHAKCF
                     IHASVQEQWGLVVNEAMAAGLPVLVSNRCGCYEDLIIEGVNGFGFDPENSQQLSELMLK
                     MSSGEIDLEIMSNEVLEHIQQFSPDYFAQGLIQSVSHASSQR"
     gene            13114..14283
                     /locus_tag="IQ233_RS09905"
                     /old_locus_tag="IQ233_09905"
     CDS             13114..14283
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006197678.1"
                     /locus_tag="IQ233_RS09905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09905"
                     /product="glycosyltransferase"
                     /protein_id="WP_193998705.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 8.5e-29,
                     bitscore: 94.9, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRILMVIPALGDVYGGTTKIVLELAESLGKLGANVDVVATNANGS
                     TTLSSPLNQWIKEKYYRVQYFSYFDFIDYKFTWSMSKWLFGNVSKYNLVHTHAIFSYPV
                     LAAYWMCQIHKIPYIATPHGMLEPWALAYKSWKKTIYFNFLEKPSLQKTSAIQMTAASE
                     VSQIKNLKLKANPVFVPNGIHRENFDSLPDKEIFYHQFPETKNKKLIIFLGRIDPKKGL
                     DLLANAFAQAYQKFPDSHLIVAGPDNTGFLPTAESYFMKAGCRNAVTFTGMLTGSIKYA
                     ALAAANIYVAPSYSEGFSMSVLEGMAAGLPCVITTGCNFPEAGEAEVASVVDINADKIG
                     NALMKLLQEPIQAKKMGDRARQFILENYTWDHIASKMLSVYQDLITQGK"
     gene            14348..14998
                     /locus_tag="IQ233_RS09910"
                     /old_locus_tag="IQ233_09910"
     CDS             14348..14998
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (43-142). E-value: 3.2e-18. Score:
                     56.9. Matches aSDomain: nrpspksdomains_IQ233_RS09910_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006197679.1"
                     /locus_tag="IQ233_RS09910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09910"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_193998706.1"
                     /sec_met_domain="PCMT (E-value: 5.3e-06, bitscore: 20.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTTTDEKYEYSYQDSETEHHHAYIIPALMEMISESAPLLESKPK
                     PRILDIGCGNGSLTNLIAQSGYEVVGVEESKSGVELAKQVFPNCQFIQGSIYNLPYAEI
                     GDNFDLVIAAEVIEHLFLPRELVRNAKKCLKPNGRLIVTTPYHGYLKNLILAVSGKMDQ
                     HFTALWDGGHIKFFSVSTITQLLELEGYGDIKFKFAGRFPYTWKSILCSSTLS"
     aSDomain        14477..14773
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IQ233_RS09910_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="3.20E-18"
                     /label="IQ233_RS09910_oMT.1"
                     /locus_tag="IQ233_RS09910"
                     /protein_end="142"
                     /protein_start="43"
                     /score="56.9"
                     /tool="antismash"
                     /translation="PKPRILDIGCGNGSLTNLIAQSGYEVVGVEESKSGVELAKQVFPN
                     CQFIQGSIYNLPYAEIGDNFDLVIAAEVIEHLFLPRELVRNAKKCLKPNGRLIV"
     gene            15028..15792
                     /locus_tag="IQ233_RS09915"
                     /old_locus_tag="IQ233_09915"
     CDS             15028..15792
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006197680.1"
                     /locus_tag="IQ233_RS09915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09915"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_193998707.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1e-18, bitscore:
                     62.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEQVTILILTYNEAPNIERTLQKLTWAKRIVVIDSYSTDETLEI
                     LSSYPQLEVCQRKFDSFANQCNYGLSKITSEWVLSLDADYILTDELINEIKTLPVEADM
                     DSYSFRFKYCVFGKPLRGTLLPPRKVLYKKEKAIYKDDGHAHRVSVEGKSRLLSAYIHH
                     DDRKSLSRWLWAQERYMVIETKKLRETPNSELSLGDRIRKQKVIAPLIILVYCLILKGG
                     ILDGWHGLYYALQRVLAEILLSIHLIEARIDK"
     gene            15860..16531
                     /locus_tag="IQ233_RS09920"
                     /old_locus_tag="IQ233_09920"
     CDS             15860..16531
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017653939.1"
                     /locus_tag="IQ233_RS09920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09920"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_193998708.1"
                     /transl_table=11
                     /translation="MISGIIKGFYYLLLKYPMRFSGWFYKKFICPKSELKVHLGPGKSN
                     YLNGWLNVDANLITAKVDVWSNLLDPLPFRKESVDIFYSHHVVEHLPDSHLIVHFQEMF
                     QALRPGGGIRIGAPNMGNACRKYLQGDYDWFSNFPENRKSLGGRFTNMIFCRGEHLTAL
                     DESYLGEIAEKCGFVDISFPLPVKETNLKDLGISEVVLSKEYESDFAFPHTVILEARKP
                     E"
     gene            16649..17236
                     /locus_tag="IQ233_RS09925"
                     /old_locus_tag="IQ233_09925"
     CDS             16649..17236
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017804042.1"
                     /locus_tag="IQ233_RS09925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09925"
                     /product="YdcF family protein"
                     /protein_id="WP_193998709.1"
                     /transl_table=11
                     /translation="MLKLNKKYGSLILAGLILGLFSMIPIRLAIAYYHSPHPQAILTLG
                     GDPVREQFTAQFAQKNPQLDIWVSSGTSPKQALAIFQNADIANHRIHLDYRAVDTVTNF
                     TSLVDDFKRQHIQHIYLVTSADHMPRAKTIATLVLGSQGIIFTPIPIPSQNPRESILRI
                     VRDSGRSLLWIVSGHTGASFHPRFREPSYAAR"
     gene            17223..17765
                     /locus_tag="IQ233_RS09930"
                     /old_locus_tag="IQ233_09930"
     CDS             17223..17765
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006197682.1"
                     /locus_tag="IQ233_RS09930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09930"
                     /product="WcaF family extracellular polysaccharide
                     biosynthesis acetyltransferase"
                     /protein_id="WP_193998710.1"
                     /transl_table=11
                     /translation="MRLDKYTLGSYTPGAPYWKQLLWYFLGSPLVESSWLPISSVKVGT
                     LRIFGASIGQGVRIKPGVRVKFPWRLSLGDYVWIGEDTWIDNLADVTIESHVCLSQGVY
                     LCTGNHNWSDPNFELKIAPIYLQESSWIAAKSVIGPGVTVGRGAVLTLGGVAAKSLASM
                     TIYAGNPAQPIKERKIV"
     gene            17878..18132
                     /locus_tag="IQ233_RS09935"
                     /old_locus_tag="IQ233_09935"
     CDS             17878..18132
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011319654.1"
                     /locus_tag="IQ233_RS09935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09935"
                     /product="TIGR03643 family protein"
                     /protein_id="WP_193998711.1"
                     /transl_table=11
                     /translation="MKLPNLDPQTIDRIIEMAWEDRTPMEAIEAQFGLQEKQVIALMRQ
                     QMKQSSFQMWRSRVTKRKTKHLKKREFIAGRFKSQNQKS"
     gene            complement(18237..18698)
                     /locus_tag="IQ233_RS09940"
                     /old_locus_tag="IQ233_09940"
     CDS             complement(18237..18698)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015364358.1"
                     /locus_tag="IQ233_RS09940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09940"
                     /product="hypothetical protein"
                     /protein_id="WP_193998712.1"
                     /transl_table=11
                     /translation="MIKSQTTLTVALAMSFMLGLFSSTPANAQETYIDSTCKQNQQLDE
                     FDRFTVMYKSEFQTKGQTYWFYSGQYIDATPIVCISQPGFQQAKPLNIKQIQLGYIDKI
                     SKDPNNQTGFLVTIRDGNGSYVPITQYRLNLSTPEKPVITKLRSWRSGR"
     misc_feature    complement(18701..18714)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.08"
                     /tool="antismash"
     gene            18889..19380
                     /locus_tag="IQ233_RS09945"
                     /old_locus_tag="IQ233_09945"
     CDS             18889..19380
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006197684.1"
                     /locus_tag="IQ233_RS09945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09945"
                     /product="DUF1499 domain-containing protein"
                     /protein_id="WP_193998713.1"
                     /transl_table=11
                     /translation="MSHLPTAFTQRLLRLITFVIFLTLISGFILPAPTWAESSGLGVDH
                     GHLSSCPASNNCVVSQDADAKHAIDPITYHVDRDAARETLLKVLSVVPRTEVVEQTDNY
                     IHALSKSRIFKFVDDVEFYFPANEPVIHTRSASRIGESDLGVNRRRVEQIRLALRDLNI
                     "
     gene            19557..19949
                     /locus_tag="IQ233_RS09950"
                     /old_locus_tag="IQ233_09950"
     CDS             19557..19949
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015116021.1"
                     /locus_tag="IQ233_RS09950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09950"
                     /product="MAPEG family protein"
                     /protein_id="WP_193998714.1"
                     /transl_table=11
                     /translation="MLPWTGLITALTLLLYFVITINVGRARAKYKVSPPQMTGNPDFER
                     VVRVQQNTLEQMVFFLPALWLFSFYVSPLWGSAIGAVWVVGRIAYAWGYYKAAEKRAIG
                     FAISSLSSIVLLLGSLVGVILSLVQS"
     gene            complement(20001..21038)
                     /locus_tag="IQ233_RS09955"
                     /old_locus_tag="IQ233_09955"
     CDS             complement(20001..21038)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     mycosporine: Dala_Dala_lig_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012411846.1"
                     /locus_tag="IQ233_RS09955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09955"
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="WP_193998715.1"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 1.9e-20,
                     bitscore: 67.7, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLLRILHLVGSAHNDFYCDLSRLYAQDCLTATADRSRYDFYIAY
                     ITPDGQWRFPRSLNREDIALTKPIPLVQAIKFLTTQNIDLVLPQMFCLPGMTYYRALFD
                     LLNIPYVGNTADIMAIASHKGRTKAIVAAAGVNVPSGELLRPGDVPTITPPVVIKPVSS
                     DNSLGVALVKEASDYEAALQKAFEYADEVIVETFIELGREVRCGIIVQDGELVGLPLEE
                     YQLDPEEKPIRSYADKLQQTDDGNLRFSAKDNMKSWIVDPNDPITQKVQEVAKKCHQAL
                     GCRHYSLFDFRIDPQGEPWFLEAGLYCSFAPKSVISCMAKAVEIPLNKLFMTVINETLS
                     SHNSK"
     gene            complement(21186..22583)
                     /locus_tag="IQ233_RS09960"
                     /old_locus_tag="IQ233_09960"
     CDS             complement(21186..22583)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     mycosporine: ATP-grasp_3"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006197688.1"
                     /locus_tag="IQ233_RS09960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09960"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_193998716.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 3.6e-07, bitscore:
                     24.9, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQSISLSLAESPTSSMGFRVKIVALFQTLGTLTLLLIALPFNAL
                     IVLISLLWGVVRSPFRKKAVVAAHPQTILVSGAKMTKALQLARCFHAAGHRVILIEGHK
                     YWLSGHRFSKAVSGFYTVPAPQSDPQGYIQAIVEIVKKEKVDVYVPVCSPVASYYDSLA
                     KPALSEYCEVFHFDADVTKMLDDKFAFTDQARSLGLSVPKSFKITDPQQVINFDFSQET
                     HKYILKNIAYDSVRRLNLTKLPCDTPEETVAFVNTLPISSENPWIMQEFIPGKELCTHS
                     TVRDGELRLHCCSNSSAFQINYENVENPQIREWVQHFVQSLALTGQVSFDFIQAESGTV
                     YAIECNPRTHSAITMFYNHPGVADAYLGKTPLPNLTEPLASSKPTYWIYHEIWRLTGIR
                     SWKQLQTSVNTLLQGTDAIYQLDDPVPFLTLYHWQIPLLLLKNLQQLKGWVKIDFNIGK
                     LVELGGD"
     gene            complement(22732..23565)
                     /locus_tag="IQ233_RS09965"
                     /old_locus_tag="IQ233_09965"
     CDS             complement(22732..23565)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     mycosporine: Methyltransf_3"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006197690.1"
                     /locus_tag="IQ233_RS09965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09965"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_193998717.1"
                     /sec_met_domain="Methyltransf_3 (E-value: 3.4e-56,
                     bitscore: 184.3, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSIVGKETARPITPHSILVALLQKTLKLAQESQISPEILDSLRQ
                     GVELAAGLDPYLDDYTTPESSALKALAQKTSKEDWGKRFSDRETVRQLEQEMLSGHLEG
                     QTLKMFVHMTKAKRILEVGMFTGYSALAMAEALPSDGVLIGCEVDPYVAQFAQECFSAS
                     PHGKKIIVEVAPALETIHKLAARKESFDLIFIDADKKEYVDYFQTILEHQLLTPDGLIC
                     VDNTLLQGQVYLPADQRTANGEAIAQFNRVVAADPRVEQVLLPIRDGVTLIRRVA"
     gene            complement(23570..24799)
                     /locus_tag="IQ233_RS09970"
                     /old_locus_tag="IQ233_09970"
     CDS             complement(23570..24799)
                     /EC_number="4.2.3.-"
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     mycosporine: DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1183: 3-dehydroquinate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015206884.1"
                     /locus_tag="IQ233_RS09970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09970"
                     /product="sedoheptulose 7-phosphate cyclase"
                     /protein_id="WP_193998718.1"
                     /sec_met_domain="DHQ_synthase (E-value: 1.5e-57, bitscore:
                     189.2, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKVQASFEATETAFHVEGYEKIDFSLVYVNGAFDLKNREIADSY
                     AKFGRCLTVIDANVYELYGKQIRSYFKHYDIDLTVFPIIISEPDKSLASFEKIVDAFSD
                     FGLVRKEPVLVVGGGLITDVAGFACAAYRRKSNFIRVPTTLIGLIDAGVAIKVAVNHRK
                     LKNRLGAYHAPLKVILDFSFLQTLPTSQVRNGMAELVKIAVVSNSQVFELLYEYGEQLL
                     STHFGQVNATPEIKEIAHTVNYEAIKTMLELETPNLHELDLDRVIAYGHTWSPTLELAP
                     RVPLYHGHAVNIDMALSATIAAQRGYIPTGERDRILDLMSKIGLSLDHPLLNGDLLWDA
                     TKSISLTRDGKQRAAMPRPIGECFFVNDLNRDELDAALAEHKRLCAKYPRGGAGVDAYI
                     ESQEATLLGV"
     cand_cluster    24967..48254
                     /candidate_cluster_number="3"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    24967..48254
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[34966:38254](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      34967..38254
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="2"
     CDS             25520..25678
                     /gene="allorf_384206_384364"
                     /locus_tag="allorf_384206_384364"
                     /protein_id="allorf_384206_384364"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTLKTLNGSKRTWLTTLCGECQYHLSLFQSSYYPVFKITALVAPE
                     NSGFEYI"
     CDS_motif       25520..25546
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTLKTLNGS"
                     /locus_tag="allorf_384206_384364_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       25547..25678
                     /prepeptide="core"
                     /locus_tag="allorf_384206_384364_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.50"
                     /molecular_weight="4861.5"
                     /monoisotopic_mass="4858.5"
                     /core_sequence="KRTWLTTLCGECQYHLSLFQSSYYPVFKITALVAPENSGFEYI
                     "
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTLKTLNGS"
                     /leader_location="[25519:25546](+)"
                     /alternative_weights="4879.5"
                     /alternative_weights="4897.6"
                     /alternative_weights="4915.6"
                     /alternative_weights="4933.6"
                     /alternative_weights="4951.6"
                     /alternative_weights="4969.6"
     misc_feature    25696..25711
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.73"
                     /tool="antismash"
     misc_feature    complement(25724..25739)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.16"
                     /tool="antismash"
     misc_feature    25894..25905
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 20.11"
                     /tool="antismash"
     misc_feature    26051..26067
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 21.18"
                     /tool="antismash"
     misc_feature    26188..26202
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 24.4"
                     /tool="antismash"
     gene            26221..26358
                     /locus_tag="IQ233_RS09975"
                     /old_locus_tag="IQ233_09975"
     CDS             26221..26358
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IQ233_RS09975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IQ233_09975"
                     /product="hypothetical protein"
                     /protein_id="WP_322744530.1"
                     /transl_table=11
                     /translation="MDALRGTMLANDTSVYGIAWDWMILLLTLIGLILIYGRLYLRAAM
                     "
     gene            26379..26864
                     /locus_tag="IQ233_RS09980"
                     /old_locus_tag="IQ233_09980"
     CDS             26379..26864
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016875686.1"
                     /locus_tag="IQ233_RS09980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09980"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_193998719.1"
                     /transl_table=11
                     /translation="MELDKPTQGVTSSECAAKVMETVPLMMRFIRADMRVHSAASLSIP
                     QLRSLAFLNRNPGASLSELAEHLGVTCATASATTERLVQRNLVQRIDDPQERRRVLLNL
                     TDEGRHHLKQSQDQTRAHIAALLDHLTPEQIAHIEEGLGLLKNVFEPTEIKHINRSE"
     gene            complement(27033..28811)
                     /locus_tag="IQ233_RS09985"
                     /old_locus_tag="IQ233_09985"
     CDS             complement(27033..28811)
                     /GO_component="GO:0046930 - pore complex [Evidence IEA]"
                     /GO_function="GO:0015288 - porin activity [Evidence IEA]"
                     /GO_process="GO:0006811 - monoatomic ion transport
                     [Evidence IEA]"
                     /GO_process="GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015114495.1"
                     /locus_tag="IQ233_RS09985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09985"
                     /product="ShlB/FhaC/HecB family hemolysin
                     secretion/activation protein"
                     /protein_id="WP_193998750.1"
                     /transl_table=11
                     /translation="MFLPSWDARKKSLLFWLLVSIFLLRSITFGLLPVQAEEVLKENLI
                     FSQRFPPPQDIQPPSPAPLPTPQPLLPPPVDLLPPLLPSSIPEDVFPSEAAETITVERF
                     EILGSTVFSASELAEAVAEFTKRPITMRELFQARSQITQLYVNKGYITSGAYVPPQEIE
                     SGVIKIQVVEGELEDIKISGTERLNPDYIRSRLAIATTPPLNQERLLEGLQLLQLNPLI
                     ESVSAELSTGLRPNTSLLQVEIKEAKSFSAQVVLDNGRSPAVGSFRRRLQFNEANLLGI
                     GDGLNVTYTNTDGSNALDASYRLPLNPHNGTLSFNFGTASGNVIERPFNVLDIQSSSRY
                     YELTFRQPLVQTPTQEFALGVTASRIESEASYLEAERIPFLSLGADEAGRTRISAFRFF
                     QEWTTRNSQEVIALRSQFNLGIGALNATINPEPPDGRFFGWQGQAQWVRLLAPETLLLL
                     RANTQLASRPLLPLEQWGLGGLGSVRGYRQNFLLTDNGALASAEVQVPILRAANIGGIL
                     QVIPFADFGVGWNNSGRENPDPNTLAAIGLGLRWSQGDRFTARLDWGIPLVSVDSNNKG
                     TWQENGLYFYLQYNAF"
     gene            complement(28896..31397)
                     /locus_tag="IQ233_RS09990"
                     /old_locus_tag="IQ233_09990"
     CDS             complement(28896..31397)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1272: TPR
                     repeat-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015137996.1"
                     /locus_tag="IQ233_RS09990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09990"
                     /product="CHAT domain-containing protein"
                     /protein_id="WP_227788983.1"
                     /transl_table=11
                     /translation="MTPAWGNISESEILSFDSQNNIAESQILYETGRFAEAVESLQQAV
                     QEYQQQGNTLKQAVALSNLSLAYQQIGDWQQAQLTINTSLNLQGFQQAGTTNTNLAVLA
                     QSLDIQGRLQLLTGKLEAALDTWKQTEDIYTKLGDKNGAALAIIYQVQALRNQGFNKQA
                     IEKVKQVNQTLASQDDSLAKAAVLLSLGDTLENVGELEKSRLALEQSLAIYQRLNSPEN
                     MALSLLSLGNNAQIEQKIPQAIAFYQQTFEISPSPLTKVQARLNHLNLLIEEKQFAAAQ
                     ILIPELQSQLKELPPSRPSIYARINFAHSLGSLNTPTSQIAQLLATAVQQARSLDDIRA
                     EAYALGNLGTLYEKTQQFTEAINLTEQALMLAQTSNALEIAYLWQWQMGRLFKDQGNFT
                     GAIAAYDAAIETLESLRTDLVAVNQNIQFNFRDNVEPVYRESVALLLQNSDEKPNVKTL
                     DKARTRIEALQLAELDNFFREACLEGQKVLLDQVVDKENPHTAILYPIILPEELQVIVK
                     IPQQPLRHYTVKKSQVEVERTLAELREYILEPDRTEEVQVLSQEVYNWLIKPIESDFTT
                     NQVNTLVFVLDGALRNIPLAALYDGEKYLVEKYAVALSLGLGLLTPKPLAETPLNVLAA
                     GLVEPPPGFSTFSALPGIKLEFDLIAQTGASTKKLLDQDFTSSTLESNVTTLPFNVLHL
                     ATHGQFSSRPEETFILANDGTINVLQFDNLLRSQSDTSQQILELLVLSACQTATGDNRA
                     TLGLAGAAIKAGARSTIASLWHINDQSTAILIGEFYNELVNHKVTKAEALRRAQVKLLT
                     NYPNYRRPGYWAAYVLVGNWF"
     gene            complement(31619..32776)
                     /locus_tag="IQ233_RS09995"
                     /old_locus_tag="IQ233_09995"
     CDS             complement(31619..32776)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015137995.1"
                     /locus_tag="IQ233_RS09995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_09995"
                     /product="DUF1822 family protein"
                     /protein_id="WP_193998720.1"
                     /transl_table=11
                     /translation="MFDAAVAFAVDHELVLEMVPTSEPLEHNYSTPGGDQRAWINQICL
                     TTFLAWLQAEITPNARVHPNTAALPSFWEIVNGTAMSFDNSRLVLLPTLAMDVDELRVP
                     QEWVDIPEWVADYYLAVQVNPDEEWIRIVGYTTHQQLKTLGVYDPGDRTYSLESDHLIP
                     DLNVLWITHQLYAEEIRRASVTDLPPLPQTQAANLLQRLSNAEIKFPRLEVPFPLWGAL
                     IAHGGWRQSLYELRQGVAQPASIGQWLQEGVSNFAQQLGWEIRQFTALPSGMRSRESQT
                     SILGLSRQILIADHTYELRVFPKGNPEEQIWRFELRNANSENMIPVGLQLRLLTEDLQP
                     FPNNEDTATTPVENLYVEVMLERGEGLVWEVTPLPEEYEREILRF"
     gene            complement(32791..33966)
                     /locus_tag="IQ233_RS10000"
                     /old_locus_tag="IQ233_10000"
     CDS             complement(32791..33966)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016877859.1"
                     /locus_tag="IQ233_RS10000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_10000"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_193998721.1"
                     /transl_table=11
                     /translation="MQPRQSITEIFSTFVQLDADRFNVWATDSKLQRSIKRCLEQYPQQ
                     QSDNFWVLYWYKIWQIESNPIAVGHISAYLQEVCYWVSRKIAVNFISQFSIADCFQMAI
                     SCIYKILKNFNPEYSTNLKSYAEYAFERFLKDSLRLGKEADICTDWALLHKISRKRLGN
                     SLTNAGFNSQIINNYVLAWECFKELYTSDSQTIRQLGKPDTATWQAMTQLYNRQSLSQL
                     TPETLEKWLSTSAKAVRDFLYPKFVSVDAPIQGQDSGNLLDTLPAELPPSLLTEIIAQE
                     ESTTRETQQAQLNQVLMDALAALDIQAQKLLQAYYQQQLTQQQISEQLEIKQYTVSRRL
                     SSIKRSLLTTLTQWSQNHLHISPTPVVVDAISKSLEEWLKNYYSHTHPPLK"
     gene            34304..34543
                     /locus_tag="IQ233_RS10005"
                     /old_locus_tag="IQ233_10005"
     CDS             34304..34543
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009454932.1"
                     /locus_tag="IQ233_RS10005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_10005"
                     /product="mersacidin/lichenicidin family type 2
                     lantibiotic"
                     /protein_id="WP_193998722.1"
                     /transl_table=11
                     /translation="MSNIDIIRAWKDEDYRNSLSEEQRSQLPENPAGLIELPDEESDAL
                     SGGCSYFTGTCGRVCAVLTPRYGCTICGGGGFTS"
     CDS_motif       34304..34447
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSNIDIIRAWKDEDYRNSLSEEQRSQLPENPAGLIELPDEESDALSGG"
                     /locus_tag="IQ233_RS10005_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       34448..34543
                     /prepeptide="core"
                     /locus_tag="IQ233_RS10005_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-1.80"
                     /molecular_weight="3012.5"
                     /monoisotopic_mass="3010.4"
                     /core_sequence="CSYFTGTCGRVCAVLTPRYGCTICGGGGFTS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSNIDIIRAWKDEDYRNSLSEEQRSQLPENPAGLIELPDEE
                     SDALSGG"
                     /leader_location="[34303:34447](+)"
                     /alternative_weights="3030.5"
                     /alternative_weights="3048.5"
     CDS             34586..34726
                     /gene="allorf_393272_393412"
                     /locus_tag="allorf_393272_393412"
                     /protein_id="allorf_393272_393412"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSTPVAGIATFLSNLTVALRRLGRRWLAHFRKFPIDQDLRNNCQK
                     S"
     CDS_motif       34586..34639
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSTPVAGIATFLSNLTVA"
                     /locus_tag="allorf_393272_393412_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       34640..34726
                     /prepeptide="core"
                     /locus_tag="allorf_393272_393412_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.20"
                     /molecular_weight="3507.0"
                     /monoisotopic_mass="3504.9"
                     /core_sequence="LRRLGRRWLAHFRKFPIDQDLRNNCQKS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSTPVAGIATFLSNLTVA"
                     /leader_location="[34585:34639](+)"
     misc_feature    34933..34953
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 24.73"
                     /tool="antismash"
     gene            34967..38254
                     /locus_tag="IQ233_RS10010"
                     /old_locus_tag="IQ233_10010"
     CDS             34967..38254
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016860136.1"
                     /locus_tag="IQ233_RS10010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_10010"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_193998723.1"
                     /sec_met_domain="DUF4135 (E-value: 2.2e-118, bitscore:
                     390.1, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.1e-79, bitscore:
                     261.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNIQTIQTLESEEIKVNSDNTINQPITLCSAWYQAINLSERITS
                     LSLIPKDLSSRKINAEFAERHVQRWKSLPPFSTDSYFAQRLAINGITEAEFIDLLGESM
                     EAVRDRYPNPPKWLTDTTLAFSGHLPRHNPENQNFLDAIAPLILQGCDRLRAGIASLIE
                     TQSHLPFVPSTIVEVLWQNLPEKLLGMLTPTMVLELNVARLQGNLPGETSAARFHSFLE
                     HLSQPENTLNLLQEYPVLARQLATAIEQWVTFSLEFLQHLCSDWETIQNTFSPDNDPGL
                     LIGLDMSVGDRHKGGRSVAIAQFSSGLQLIYKPKSLAVDIHFQELLLWLNQHSDLPPFR
                     TLKVVDQSTYGWVEFAQVQNCSNSVEVTRFYERIGGYLALLYVLEARDFHFENLIASGE
                     HPILIDLEALFHPRIDESEHNKVNQYANSIMYDSVLRVGLLPNRVWSNPESGGIDVSGL
                     GTIGKQLTPDRLPYWEGVGTDEMQLKRRQMEMVGEQHRPTLNGAEINAFDYTESVITGF
                     SKIYQLLLQHREQLLAEDSLLSRFANDEVRVILRPTRTYGLLLMESFHPDLLRNALDRD
                     CYFDRLWMDVKNQPELARIIAAEQEDLHNGDIPIFVTRPHSLDLWSSNNVCIPNFLTEA
                     SGMVVRRSLEQLNETDLKQQLWYIRASLSTLATDVERVEPTNYFSTKPQTAANREQLLA
                     AARVIGDRLEELALPDKGNVTWIGLTPTLTSQLSLIPLGLDLYGGVAGVALFLAYLGDV
                     TKEERYTQLAESAVKTLQKQTKLGKSFLKFVGGFSGWGGVIYTLTHLSVLWSQPELLTE
                     AESLLEILPSAIAQDEQLDIIGGSAGCILSLVNLYHSHPCESIIQIARQCGERLLTQAK
                     SMAEGIGWVVHHAGTKPLAGFSHGAAGIALALLELAAFTGDTRFRTAALDAIAYERTLF
                     DIPEGNWLDQRDVESPGQAVNDHAFMTAWCHGAPGIGLARLRGLPHLDNDKIRAEINTA
                     LKNTLAQGFGSNHSLCHGDLGNLELLLQASLTLDDPQWKTEVDRLAAVILESIDQQGWL
                     CGVPLGVETPGLMTGLAGIGYGLLRLAAPQDVPSVLSLEPPHLNSQV"
     gene            38293..40521
                     /locus_tag="IQ233_RS10015"
                     /old_locus_tag="IQ233_10015"
     CDS             38293..40521
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017747626.1"
                     /locus_tag="IQ233_RS10015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_10015"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_193998724.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.3e-35, bitscore:
                     116.6, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFQLIQQQSEEDCGAASLASVAKHYGKTFSISRCREAVGTRQQG
                     SSLLGLKQGAEALGFNARAVKVALELFDETTVPLPAIIHWKGYHWVVFYGKQGNKYVVA
                     DPGAGIRYLEKKWFLEAWSNGAMLLLEPDSVRFFTQEDQQEKIGGLGRFLRRVWPYRAI
                     VGQTLLLNSILGLLSLASPFLLQILTDDVLVRGDRQLLTSVVIAVVVMQLVTSSLQLAQ
                     SNMVAHFAQRLQLGLIFEFGRQILRLPLSYYESRRSGEIVSRLEDIQQINQLISQAVVS
                     LPSQLFIALVSMSLMLFYSIKLTAVAGAIAILMTLSTILSLPTLQQKIRSVLVLSSENQ
                     GVLVETFKGAITLKTTAAAPQFWEEFQSRFSRLANLSFRTIQIGILNGIFSNLVSSIGS
                     IALLWFGSTLVIQQELSIGMLLAFNSMNGNFTSFIKTTIDFVDEYTRAKTATQRLTEVI
                     DATPETLDHSQKPWVKVQSNADITCTNLNFHHPGRMELLQDFSLTIPGGKVIALIGKSG
                     CGKSTLAKLIAGLYPLQSGNIRFGIYNLQDLALDCFRQQVVLVPQEAHFWSRSIMDNFR
                     LGSPDITLEQIVQACQIAGADEFISNLPDKYQTVLGEFGANLSGGQKQRLAIARGIVNN
                     PAVLILDESTGALDPVSEAEVLNQLLTHRQGQTTILISHRPKVIQQADWIVMLEKGELK
                     IQGSPEVLSQQVGEHLDFLDGVDISRVNGFTKNPANFHLNGSSAISIR"
     gene            40542..42050
                     /locus_tag="IQ233_RS10020"
                     /old_locus_tag="IQ233_10020"
     CDS             40542..42050
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1029: RND family
                     efflux transporter MFP subunit"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015140178.1"
                     /locus_tag="IQ233_RS10020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_10020"
                     /product="biotin/lipoyl-binding protein"
                     /protein_id="WP_193998725.1"
                     /transl_table=11
                     /translation="MVNHINADSLPIVESDEFLPPIGNWARLGSLVIVAGVGIAIALAS
                     VIEYKVTIKGEASIRPMGELRLVQAATEGQVTNIFVKENQAVKKGDVLATLDDSRLQTQ
                     KSQLQNNIQQTQLQLLQIDAQVKALNRQIQAETQRNSRAVISAQASLNRAQRNYQDQQI
                     NVKSQVEEAEANLKRAQNELTQAQVQLRSARANFQSTEAAMSAAQAKRDRYQKVVQAGA
                     LSLNQLEEVQLDVAQQQHAVEVQRATVEAQQQIIAQQQQSVAAVRAQLQRVEAGLNPSD
                     AEIAIAQETIAQESAGGEATLAILNREWEALFQQRIQIKNQIQRDTSELQQVESNLSQT
                     KITVPEDGILSQLNLRNPGQSVRVGEEIAQIFPSNAPLVIKAAVSPNDVSKLAKDQKVQ
                     MRVSACPYPDYGTLKGVVSQISEDTVKSPGNQNVSTVANASSSMQGGASSFYEVTILPE
                     SFFLGKSNHQCTIQPGMQGRADIISRSETVLKFLLRKARLIADW"
     gene            complement(42342..43190)
                     /locus_tag="IQ233_RS10025"
                     /old_locus_tag="IQ233_10025"
     CDS             complement(42342..43190)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015138297.1"
                     /locus_tag="IQ233_RS10025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_10025"
                     /product="DUF928 domain-containing protein"
                     /protein_id="WP_193998726.1"
                     /transl_table=11
                     /translation="MKNLQLTIALSIAFISNISSPLQLQALPINHHLTSIEFIPPPPPP
                     DRSAAGSRSGAASRGCDAANQTVTALVPTYQQTLNQGTPAVVPITQVWGLTNTENPNFL
                     FFVPYNASSIANIEFVLQEQTENKSKTLYRTSLKPPESPGIISVNLPPSEASLQVGKMY
                     HWFFKVRVQCDQKQPTKLDYADGWVQRINQNSTLTAQLQQATLPQQATLYAANGVWYDA
                     IMSLAELRFSNPQNETFLAQWTTLLDSAGLEEIANQPLINCCQPSLKNNLPAGQNPVPE
                     N"
     gene            complement(43218..45593)
                     /locus_tag="IQ233_RS10030"
                     /old_locus_tag="IQ233_10030"
     CDS             complement(43218..45593)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015138298.1"
                     /locus_tag="IQ233_RS10030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IQ233_10030"
                     /product="CHASE2 domain-containing protein"
                     /protein_id="WP_193998727.1"
                     /transl_table=11
                     /translation="MSKLVVLKLGTGSFEAGFPVTLQIGDENVRPVVEITGELPPDSDI
                     PLCYHQWQSIYCQLKFSGRPIGIPKRSPQTPSLVDCEKAGDVLKFHLNTWLSSTSFRPI
                     REKLLEKLLPSDQIRILLQTNDLRLQKLPWHLWDLLERYPQAEIALSAPCYEQVSRNSP
                     PQLQVKVLAILGNSQGIDIQTDSQLLKELPHANTTFLVEPSSKDLTDQLWEQDWQILFF
                     AGHSATDKSGNEGKIDLNQTECLTISQLKYALRKAVERGLHLAIFNSCDGLGLAREFAD
                     LHIPQIIVMREPVPDRVAQEFLKYFLEAFARGESLYIAVREARERLQGLESQFPCATWL
                     PVIYQNPAAMPLLWRELHFNQSIQQISSVPKISTRGGVNLGKALSAVILASIVITPLLM
                     GVRYLGLLQSWELMAFDHLLSLRPQEKPDSRILVITVTEEDVQAQSDNRRGSLSDEALD
                     QLLAKLEAYQPRVIGLDIYRDYAVQPAYPMLAERMRKSDRFVAVCQVSNPQASKPGIKP
                     PPEVSPDSLGFSDIVIDADHVVRRHLLALTPPPSSPCTAPYALNVQLTLRYLYAEGIQL
                     QFSPDGAWQLGKLTLKPIEAHTGGYQGIDALGHQILLNYRSFPNLEAMTSGRSLTIAPR
                     ITLQQALAGQLQADAVKDKIVLIGTTAESFRDYSLTPYASSQGKPQEIAGVYLQAQMVS
                     QLLSAALDGRPLLWTWNVWGEVIWVWVWAMTGGLLVVYLRQLAYLGLAVGVAFLSLYGF
                     CLILLILYSCWVPFVPAAIALGGSAVILVAVIKPIKKL"
ORIGIN
        1 taatggataa tttgaaccta tttttgaact agttttgccg atgggtattt cactaaccac
       61 tgcaaaacta ttttagaata tcctacttgt atatccatca tactaaattt ttatctaaaa
      121 atagtttaaa tatagcctaa taaggtatta cttttcacca aattgttatg cgaattttaa
      181 ttacaggaat ttgtggtttt gtcggttcta ccttagccaa agcattacaa gaatattttc
      241 cagaatatca aattgttggc attgataatt tctcccgatc agggagttgg ttgaataaag
      301 caaccttaca gcaacgagga attgaggtaa ttcatagcga tattcgccat agcagtgacg
      361 tagatgcttt accttctgct gattgggtaa ttgatgctgc ggctaaccct agtgtcttag
      421 caggagtaga tggtaaaacc agcagtttac agttagtaca acataatcta ctcggaacaa
      481 ttaacctttt agaatattgt aaacggtatc aagctgggtt tattctgctg tctaccagcc
      541 gagtttattc catacccgga ttaagtaaat tacaagttgc tgaagctaat ggagcatttt
      601 atcccgttcc tgaacaaatt tttcccgtag gtatttccac aatgggggta gctgaaaact
      661 actctaccaa tccgccagta tcattgtatg gcagtacaaa ggtagcttca gagcatttag
      721 ctttagaata cggtgcaacc tttgaatttc ccgtttggat taatcgctgt ggggtgatgg
      781 cgggagcggg acagttcggc catccaggac aaggtatttt tgctttttgg attcatagct
      841 ttcgagaaca gcgatcctta aaatatattg gctttggcgg aaaaggttat caagttcggg
      901 attgtttaca tccacaagat ttaattaatt tgctacaaaa acagtttgct gaaccattaa
      961 atacaaataa acccagggtg gttaatgtca gtggtggagt taagaacagt atgtccttgc
     1021 gacagttaac ccaatggtgt gcagacaagt ttggtagtaa tgaagttctg gaaactaata
     1081 ttgagcggac atttgatatt ccttggatgg tgttagatgc gagtttatct gagaaagttt
     1141 ggggatggac acctcaaatt gggatagaaa aagtgctaga agaaattgct atttttgcca
     1201 gtgaacaacc agattggtgt aggctatcag cgacatgact tataaaatat tgtatatttc
     1261 agcagtgatt cctgatacaa cttctggggg acgctttgct atgtatcgtc acctgattat
     1321 aaaaaaagac tttgaggtgg ctgttgctag tacaaatttt gttaaattac ctattaaaca
     1381 gcagctttcg attcgtagaa atcgattaat tgaaaggctc agacgcactc gattatgtcg
     1441 attgatatat aacttagaat acctactgaa ctggattaat attcctggtt cattgttaaa
     1501 atttgctgat gactttaagc cagatgtaat tgtatctgta gtagatgatt ggcatctggg
     1561 attagcattt cagttggcgc accaacttaa ggttccactg attgttaatt tccaagattt
     1621 gttttgtcta tctcaatttg ttcctttgtc agcgcgtcct tatcctgtga tcacatcttg
     1681 gctcatccaa cgttaccatc aagttaatga gttagccaat caggtatttt ataccagtga
     1741 aggtatgaaa gaatggtttg gagttgatga tcaaggaaat gttctttatc ccgttggtga
     1801 ttttgatgtt caggtttcca tagagcaaag agcaaattcg caagataaag ttaaaattat
     1861 ttatgctggt aattgttatg gtgcttacgg tcgtatgttg ttgcgcctag ctgaatcggt
     1921 gcagaaacat caacatattc atctccagat ttttgctgcg ggaaatgatt ggacacccga
     1981 aaaactacag gagatgaccg aagcaggaat ttatcaaggc tttaaaccat tcgatgaatt
     2041 aaaagatgaa ctcaaacagg ctgatgcgtt tttaactgtg atgagttttg aaaagtcaga
     2101 agaaattttt atgcggacga gttttaccac caaatggtta gattatgtcc cctatgctaa
     2161 accagtgttt gtttggactc cagaatattc aacagcctgt ggctttgcca aaaagtatca
     2221 gtcagggatt ccggttattc acgacgatcc agaggtattg ctcaaagtta tcagcgaaac
     2281 agcatcaaat tcgatggctt ggtcttcagc ctgtgaagga tctcgtcgag tggctgagac
     2341 tgtgctgaac gcagagcaaa tacatcatct gtttgttgag cgtgttacta atgtttgcca
     2401 agaatgcaat actaaaaatc ttcaagattg aatttactca gcataacgat gtgaacaagc
     2461 gcaaaattat tgtaatttct tctatttctc ctcaacccac cagtgctggg caaattttac
     2521 tatatcggca tttaaatcaa gctactggct gggatgttga tatcgtaccg aatccctatg
     2581 aaattaaaac tgatagatgg caaacaaagt taattaaaag gctagaatat actcgcttcc
     2641 atccttgggg tcatgatttc caagttatag atcaggggat ggtgtgggac aatacactac
     2701 tcaattccca tcaacgggtg tttaattctc aaactggcga caaaaccata gttctgacta
     2761 tttctcatgg tgatggttgc tgggctgcac agagatttgc tcaccattat caattacctt
     2821 tagtaacaat ttttcatgat tggtggccag atattcctac tttacataaa cctttccgtc
     2881 agctattaga gcgacgtttt gagcaacttt accagcaatc taatttagct ctgtgtgttt
     2941 cagagggtat gaagaatgct ttgggttcac attccaatag tacagttctt tatcccatac
     3001 ctgctttact caaggaggaa ataattacac aatatcagcc tgaaaatgat caaatatcat
     3061 ctccattaca ggtggtttat tttggaaatc tccacgagta tggaccaatt ttagctcaat
     3121 tacttgaggt gacaaaagat aatgctaaga ttcaagtaca agttcgcgga tctaacccaa
     3181 attggtcagc agattttcgt tcagaaatgc gcgatcgcaa tttatggtta gactttgccc
     3241 ctagagagga attaaatcat tggttagctt cggctgatgt gtttttagta accatgagtt
     3301 ttgatcctgc tttgcggcga cgtatggaaa ccagttttcc atctaagttg cctgaatatg
     3361 ctcaatttgg taaaccttta gtgatttggg gacccaatta ttgttcggct attcgctggg
     3421 ggagcgaagg cgatcgcgct ctttgtataa ccgatgaaaa tcctcaagtt ctagtttctg
     3481 ctctagaaaa aatcaagggc ttcccagaac agcaagaata ctatgctaaa cagagtagaa
     3541 ttgctgctca aactgagttt aatccttcta ttatacagaa ccagtttgtg gagagtcttc
     3601 aaagtctaat taaataaagt atttaatcta tatagattgt tatgagcagt tcttgtacca
     3661 tcaaacactt ttctacagaa ctatcaggcg gatctggtat tgctgctcaa agactacaca
     3721 aagccctact ggaaaaaagt atatctagcg aactactctt ccgtaaaggc tcaacttctc
     3781 tccctcacag cataagcgat cgccgtaact catcactacc ttggcgtgat ctagattcca
     3841 ttaccattag caaagaatgg aatcgctcag ttaacgatag aagtttgttc acaaatcccc
     3901 aatggattta taaaacccaa cttaaagact ttggtaaact cccagaaatt attaacttac
     3961 attggatttc tcgctggata gatcaaccta gcttttttga ttctattcct cccgatattc
     4021 ctattgtctg gtcactccat gacatgaacc ccataactgg tgggtgtcat catgcgctag
     4081 attgcgaaaa attcgccact cattgctgtg attgtcctaa tttgaaaaac tcaggtaaac
     4141 acgatcaagc atcgaaaaac tttgcactca aagccaaact ttatcaacat ctaaatcttc
     4201 attttgtcgg taacagcact tggacaaccc tacaagctca aaaatcacaa ctgggtaaat
     4261 acgctcgttc tatccgcaca attcccctag gaattgatat caaagattat caacctattg
     4321 atcgatccat tgccaaagct gctttacgag tcaatcctga tgatttggcg atcgcctttg
     4381 cttgtgccga tctgtctgac aaaaacaaga atttgcctat cctactagaa gcaattgccc
     4441 agttatctaa acaccactct atcacgctga ttctatttgg ttcgggtcaa attcccgaat
     4501 taaacagtca aattaccacc gtaattttag ggcatttgtc ttctccccaa cttcaaagtc
     4561 ttgcctactc agctgctgat atctttgtta tgcctagtca aattgaatct tttggtttaa
     4621 ctgctctcga atcaatggcc tgtggtacac cagtattagc atttcgcaca gggggaattc
     4681 ctgatctggt tattcatggg gaaacaggtt ggttagcaga tgacattggt tcgattgaat
     4741 ctctttatga aggactccac tggatgctac aacatcccca agagcgatcg catctaggaa
     4801 aagcagcccg tcagcgagtt gagcgagaat ttacggatga tatcatggct aatcgctata
     4861 tcaatcttta tcaggagctt attagcccat gaaacgggta cttatccgcc ccacatttca
     4921 agattggtgt gaaaataaat tattttcaga tggcacatct ttcgcatcag tttatcaaga
     4981 agccttttct ctatggaaac aacaggctgc aaaaattgga tttcaactcg atacctggga
     5041 tcaagcacct ttagagacag cagatatatt ttggttttta gaccttcccc catctcgtca
     5101 agaatttaca cgtattcgcg ctcaattaca acccaaaacc cctatagttc tgcaaattct
     5161 agaaagtcca tttttagcaa ttcacgcctt taataatgcc aatactcaag atttcgacgc
     5221 agttttaagt tatgaatata tagaaactat taaacagaaa gagcgccatt ttcattacca
     5281 tttacccaat caactgcgac aaccacagac taatctatct tactcagaaa ggaaaggctt
     5341 gttgcttatt aacagcaacc gagtagcagg attttttgga atgcgtcagg tcggtttttc
     5401 tggtatcccc ggattaggaa agtttttggc aggttggcac tgttctttat ctatgtttag
     5461 cgaagcctta tcaggtgaac tctactctga gcgaagaaaa ttagcccgga ttgctgagtt
     5521 aatatctctt aattttctgg atatttacgg acgagggtgg aatggagaac aaatttcttg
     5581 gtgtccactt tatgaaaatc gttcctataa ctcttggcga ggaataccca ctatttctaa
     5641 atgggattta tgcgagcagt accgatttgt gttaagcttt gagaatttta agggcagacg
     5701 tggctacatc agtgaaaaga tttttgatgc catgtttgct ggctctgttc ctgtctattt
     5761 aggagatgac cgcattaccg attatgtgcc tagtgatgca ttcgttgacg ctagaaattt
     5821 tgataattat cctgatttat taaaatattt aatcacttgt cctgaagcag catggctaga
     5881 tatgcgtcaa gcgggtcagg ctttcattaa atcagatgaa tttcaatgtt ttaattctct
     5941 tcaatttgca gaaattgcta cacaaattct gaaaaaagta actgtttgac atgaaacttc
     6001 aaaatgtcaa agatagactt cgtaactcta aatttttgag gatactctat gctaaattat
     6061 taagtcgtgg taattctttc aacttaaaag gcaataataa tatattagat acagcagggg
     6121 ctattttaaa aaaatgttca ctgcaagttg ttggtaataa taacttaatt tcaattgatg
     6181 ttggatgtta tctggaagga gttaaaatat ttttgcaagg tgataattta aaattaaaga
     6241 tagggagaag tgtatttata ggtcaaggct ctgttttatg gatggaaaat agtgatgggc
     6301 ttatcgaaat aggagaattt acatctatag aaaaagtagc catagctgta gctgaaggta
     6361 aaaaaattat tataggtaaa gattgtttag tttcctatga ggtagatatt agatgcagtg
     6421 actctcatgc tatctttgat caagaaaaaa aatgtagaat caatcccgca gccaatatag
     6481 aaattggtaa tcatgtatgg ctaggagcaa aatgtttaat tcttaaagga gtaaccattg
     6541 gagacggttc gatcattggt gcaggttccg tagttactaa gtctgttgaa ccaaattcag
     6601 ttgcagctgg caatcctgct aaagttgtta gaagtgatat tgtttggacg cgatcgcgaa
     6661 gtgattcttt tcctgaataa ataccttgca tacatacagc agattccagg taaatgaggt
     6721 ataaatctta atactgaaac tcttgtgata tgggcatctt gccctccctt gtatacccct
     6781 ctataatcaa atgtgctgta aattggtatt agtttatgac cactaacttt ggtattgtta
     6841 cagcctgttg gaaaggagat tattttctcg ttaaagcaac ctgtgctagt attcgccatt
     6901 tcctcggaga tgtccctatt tgtgttatcg ttgatggaga tttttctatc caagaacttg
     6961 aaaatctcta tggtgttcag cctctttatt tatctcaact atctaatcca gaactccgta
     7021 ggcgatgtcc tggatctagt cgtgctaaac tggctgctat ttgggaagga ccatttgagc
     7081 attttctcta tttggatagt gacgcaattg tttggggaaa cttactggaa aaatttgact
     7141 taactactac agattttgta gtgatgcgtc ctcctttgta tggctgtcta cctaaacatg
     7201 aggtttctcg atggtttttc aatgttgata ccctcttaga aattgatcct accttcgagt
     7261 ggcagaatca accttatttt tgtgcaggtg cttttgctgc taaacgaaac tgctttgatt
     7321 tacaagaata tttgagatta gaggctttgg cagataaata tccagagtta tttaagtttt
     7381 gggatcaggg tattgttaac tatatggttt tttccgccaa ccaagcaggt ctcctcaaat
     7441 ataaagttgt tgatatccag gtagtgacag cagatcattc taagagtaca ttagaagaac
     7501 aatacccttg ttctatttac aaaacacccc aaaacgtcga caaaacaact attattcatt
     7561 tttgtggaaa caagccattt attcataaaa gaaaatcttt cagcaagcct tttactacat
     7621 ttaggttatt acattaccaa aagctaatgg gcgataatat tagtggaaaa ataaaatcca
     7681 tatttcagct attttgtgaa gagtttgagc ttttaaccaa caaagcaaaa tctaaattta
     7741 aaagaatcat taattctcaa taactttcaa aaaatgaaaa ccctgtttaa atcaacacta
     7801 aattatcttg aaaagatata ccatttttct tcatttaggg ggcattcctt ttggaatata
     7861 ccaatagata gcaattccgt ggtagttgat ctaggcgcta atctatgtga tttctcttct
     7921 gaagttaaga aaaggtttga atgcactgta tttcccgtag aaccaaatgc aactcttaat
     7981 cccaatgatt catactttct tgattctgta gataggttag ctataactaa ctgtaatggt
     8041 gaagttgatt tcacgatatc cgaaaattca gaagcaagca gcctttactc aaatcttgcc
     8101 aatctatttg gatcaacaaa gacaattaaa gtaagaggta tgtcgttgaa tgaatatctt
     8161 aaactcaaag agatagaagg cagtttatcc ttattgaaag ttgacattga aggtggagaa
     8221 atagacctac tttcaaaaat acctctcaag gagcttgaat tgattgatca gatgactgtt
     8281 gaatttcaca gctttctaga tccttctttg gagttagagg ttatcgccat aattgataga
     8341 ataagcaaat caggtttctg ggtcattaat tgtaatcatc cctattatga cgatgttcta
     8401 ttttttaata aaaaactatt caaaaaatat cacttcaaat gcttagatat ttttattatg
     8461 aagatagttt atataatcag aggaaaaatg cataaattga ttggtactca taaatgaagc
     8521 ttgaaatttg caaatctcaa atcaaaataa ctagcaaata ctaaaaatgg tcagcatttc
     8581 tgctttaatt ccaacgtata aaagagttga taagctagaa aactgtctcc aaaaaattct
     8641 ttcctgtgat cccctcccgt cagaaattat cattcatatt gacgcaggtg attccgaaac
     8701 agaacctttt cttatcgctc aaaattatcc cctcgtaact tggatcagca gcaacacaac
     8761 ccaaggacct ggcggaggta gaaataaact gatcaagcaa gccaaatttc ctattattgc
     8821 tggttttgat gatgactctt ggcctttaga taaaaattac tttgccatag cgacagagct
     8881 tttttctctt tatcctcaag cctcagtaat tactgctcaa gaggtacgac ctagcacatt
     8941 tccaaaacaa ctaaataatt ttataaaaga agtgaactgc ttccaaaact gtgcttgtct
     9001 catgcgtcga gaagcttttt tacaaacccg tggctattta cctctacgct atgcctatgg
     9061 catggaagaa gctgatgtag cgttacaact tcttgattgt ggttggcaaa tactagaatc
     9121 atttaacttg tgcgtatttc acgatactca attagaacat cacaatcatc catcagttaa
     9181 cgcggcacat attgctaata cagccctttt agcttatctg cgttatccaa ttacttattg
     9241 gcctttggga atagttcagg tgtttaacag aatgcgatat gcagctagtg tagggagatg
     9301 gaagggtatc agccaaggat tatcgcaaat tcctcatcta ctttcatgct acgctaatca
     9361 gcgtgatcca gtgcaggttc atacactgga attaagccga aaattagcat caaagtcatg
     9421 aataaaaatt ctaggaattg gatttgctgc caaatagggg caagagaaca ctatgcaatt
     9481 cccagagcat tacatcagca tgaaaaatta gctcatctga ttactgatgc ttgggttact
     9541 cctgtgtctc ctctcaaaat tttaactcaa tcaggactta gagaacgctt tcatcctgcc
     9601 ttagctaagg tacaagtcca cgcctttaat agtttcctta ttcgttttga aatcagtcaa
     9661 aaactacaaa agcgttttgg gtgggaaaca atcattgccc gtaataactg gtttcaacaa
     9721 caggctatta aaaagcttac acaattaact gaaaaattca ctactcctcc cattctattt
     9781 tcttatagct atgctgcatt agaattattt aaatttgcta aaaaacaggg ctggtacaca
     9841 gttctaggtc aaattgatcc tggtttgtgg gaagaacaaa tagttattca agagtctgaa
     9901 aaacatcccc aatatcataa aaattggcaa cctgcacttc gtgaatattg gcaaatctgg
     9961 caagaagaat gtaaccttgc cgatgccatt gtagtcaatt cacattggtc atctcaactt
    10021 ttagaaaaaa caggtattga agtcaagaag attcatatca ttcccttggt atatactcca
    10081 ccaaaaattg ctaataaatt tatccgcact tatccagaat cattttctca gaaacgacca
    10141 ttgcgtgtgt tatttctggg gcaggtaatt ttaagaaaag gaattgcatc tgttttagaa
    10201 tctataaaat ccctggaagg atatccaatt gagttctgga ttgtgggatc taaagaactt
    10261 caaattccgt catactttga aaaccatcct caagttcatt gggtaggtcg tgtcaaccgt
    10321 agtgaaaccg ctaaatatta tcaactggct gatgtttttc tctttcctac tctctccgat
    10381 gggtttggac taactcaact cgaagcacaa gcttggcaac taccaattat tgcttctcgt
    10441 aattgcggtg aggtagtggt ggatggtgtg aatggttggc tattacctga agtaagtaat
    10501 gtagctattg ctaatatatt gaaactctgt cttcatgatc cagaaaatct cacagcatta
    10561 tcaaaaaact gtcaaattac caataaattc accctcgaaa cacttacaca acatttacta
    10621 aaattctaac catgccccca aatcttgaaa tcccttttag ttattatatt gcggcagccc
    10681 tattgctctt cttctttatc gaagcagcaa gtaaaataca tcggagttgg gctattcccg
    10741 ctttgatgac ctacctaact acaggaatgt ggtacttcac cgaagtcttc tatactcctg
    10801 agcggttgac tatttttaat agctctattc tggagcaggc ttactatcaa atttgtattt
    10861 tcctgatttt attccgttgg ttactgccca gttttactcg caccatagga aaatattcat
    10921 ctaaagtcaa tgctttcaac tggtttacct taaatcctca tcggttactg caaatcttgc
    10981 tggtgatgtg gatactttta ttcatttatg gtattagtcg cttagactgg aattttttcc
    11041 aagctttact tcctcaaggt ggacgctggt ctcctaaact atggaatcga ggtgcagttg
    11101 gggggggaac tgagtttatt gtttctgctg ctgggtacac ttacacttta atatgtgcga
    11161 tgtttggggt cttgattttc tttcaacgtc aaccccaagc taaagtaatt aatttggtga
    11221 tgataatcat ctcttggcct gctttctatc tttctggcac acgaaactcc tttctcgctg
    11281 tagctatgcc agcatatatg acatatttgt tgacttctcg tcacaagtgg tgggtgaaag
    11341 tagcactttc ggctggacta tttgttttga ttaactactt gatgttaatc gcaattagct
    11401 ttcgtaatac gggtattgat gcttattttg aaggcgctgc tactctaaat actgagagta
    11461 aacatgaggg tttaaatatg gctgaggaat tattttatat caataaattt tacgaacaag
    11521 gcgaattaac tttacagtat gggatggact atttggctga atccctaaat ctcatcccta
    11581 gatttatatt cccggataaa cctctaatcg gacacgaata taatttactg cgaaacccca
    11641 gcagtgggat tcaggcaaca atctcagccg gatttattgg gcgtggagtc ctgaattttg
    11701 gcccttggtt tggacctatt gtacctgcta ttttaatggg actttggagt gctttcctag
    11761 cgcgcctttg gaatcaaaga tcatcaattt tacggctgtc acttttttta gtaggtttgg
    11821 ggattacacc aaacttaggg cgtgacatta cgcttcttgt tctttggcct atactttttg
    11881 gctatgttat tgtccgctat ttagaacgcc ttgaacgtcg ccgaatgctt agatatgcaa
    11941 ctcagtatca ctattataaa catgaattgc gctcctaaca acttacaaat agcaatttta
    12001 tttgctaatt atggtcccta tcatatcgcc agagttgcat ctgcctatca cgcttgcaaa
    12061 tctagcggat gtaatgtttt tggcattgaa ttagctcgtt cagaagtaga atatccctgg
    12121 gaaatacaac ttgataaatt tcctggtcaa attcactcag ttatcgatga tgttccccta
    12181 gaaaaagtaa aatttagtca tttatttggg aaattaatct ctctcttgaa tcgaacttgt
    12241 cctgatgtta tagcaatttc tggttatgct cgtccttcta tgcttgttac tttattatgg
    12301 tgtctctggc atggtaaatc tgctattctt ttatctgaaa caacagagaa tgatgaacct
    12361 cgttcttggt ggaaagaaaa aattaaaaag ttgctaatta caagatataa agctgcctta
    12421 gtaggaggac taccacacaa gcgttattta atcaagttgg gaatgccctc tgaagctatt
    12481 tttttaggct atgacgtagt tggtaatgat gttttccacc ctaatcagat taaatcctta
    12541 tcttgtccat tagctcaacc attcttttta gctattaata gatttgttag caaaaaaaac
    12601 ttaccatttc tcctttcagc ttatgctaaa tatcgtcaaa cagcaggaac tgatccttgg
    12661 gatttagttc tctgtggaga tggtgaacta cgtttgctaa tagaagagga aattactaat
    12721 cataaaatgc aaaattacgt ccatcttccg ggttttctgc aacaagatca acttttacct
    12781 tattttgctc atgctaaatg ctttatccat gctagtgttc aagaacaatg gggtttagtt
    12841 gtaaatgaag caatggccgc aggtttacca gtattggttt ctaatcgttg tggctgttac
    12901 gaagatttaa tcatagaagg cgttaatgga tttggttttg atccagaaaa ctctcaacag
    12961 ctaagtgaat tgatgctgaa aatgagttcg ggcgagattg atttagagat aatgtctaat
    13021 gaggttttag aacatattca gcaattctcc cctgactatt ttgcccaagg tttgatacaa
    13081 tctgttagtc acgcttcatc tcaacgttaa tgtatgagaa ttttaatggt tattcctgct
    13141 ttgggagatg tgtatggtgg aacgacaaaa attgttcttg aattagcaga atctcttggt
    13201 aaattaggtg ctaatgttga tgttgtagct actaatgcca atgggtcaac aaccttaagt
    13261 tcacctctca atcagtggat taaagaaaaa tattatagag tccaatattt ttcttatttc
    13321 gattttatag attataaatt tacttggtca atgagtaaat ggttatttgg caatgtatct
    13381 aagtataatt tagtccatac tcatgctatt ttttcctatc cagttctcgc tgcgtattgg
    13441 atgtgtcaaa tacacaaaat tccttatatt gcgacacctc atggaatgtt agaaccttgg
    13501 gcattagctt ataaaagctg gaaaaaaaca atctatttta attttttgga aaagccatca
    13561 ttacaaaaaa caagtgctat ccaaatgaca gcggctagtg aagttagcca aatcaaaaac
    13621 cttaaattaa aagctaatcc agtttttgta cctaatggaa ttcatagaga aaattttgac
    13681 tctctccctg acaaagagat tttttatcat caatttccag agactaaaaa taaaaagtta
    13741 attatatttt taggacgcat tgatcccaaa aaaggattag atttattagc taatgctttt
    13801 gctcaagcat atcaaaaatt tcctgatagt catctgattg ttgccggacc agataataca
    13861 ggatttttac ccactgctga aagctacttt atgaaagcag gttgtagaaa tgctgtcaca
    13921 tttacgggga tgttgacagg ttctattaaa tatgcagctt tagcagcagc taacatctat
    13981 gttgcccctt cctattccga aggttttagt atgtcagtcc tagagggtat ggcggcgggt
    14041 ttaccctgtg tcattaccac tggctgtaat tttccagaag ctggtgaggc tgaggtggct
    14101 agtgttgttg atattaatgc tgataaaata ggcaatgcct taatgaaact tttgcaagaa
    14161 cctattcaag cgaaaaaaat gggcgatcgc gctcggcaat ttatcctaga aaattataca
    14221 tgggatcata tcgcctccaa aatgctttca gtttatcaag acctcattac tcaggggaaa
    14281 taatttaagc tagtaagtat tcagccgtca aagtcaacat ttagtaaata atctggtaga
    14341 aaaaacaatg tccacaacta ctgatgaaaa atacgaatac tcataccaag atagcgaaac
    14401 agaacaccat catgcttata ttattccggc tctgatggag atgatatctg aatctgctcc
    14461 tttgcttgaa agtaagccaa aacctcgcat tttagatatt ggttgtggta atggcagttt
    14521 gactaactta attgcacagt ctggttatga agttgtggga gtcgaagaat caaaatcagg
    14581 agtagaatta gccaaacaag ttttccctaa ctgccaattt attcaaggta gtatttataa
    14641 tctaccctat gcagaaatag gagacaattt tgatcttgtc atcgctgctg aagtaattga
    14701 gcatttgttt ctccccagag aattagttag aaatgctaaa aaatgcctga agccaaatgg
    14761 tcgtttaata gtgactaccc cttatcatgg ctatctcaaa aatctcatac ttgctgtttc
    14821 tggcaaaatg gatcagcact ttactgctct ctgggatggc ggacatatca agtttttctc
    14881 tgtatcaaca attacacaat tgctagaatt agaaggctat ggagatataa agtttaaatt
    14941 tgccgggcgc tttccttata cttggaaatc aattttatgt tctagtaccc tttcatagtc
    15001 aaaattattt ttgcctactt acccgctatg ctagaacaag ttaccatttt aattctgaca
    15061 tacaacgaag cacccaacat tgaacgcact cttcaaaaac ttacatgggc taagagaatt
    15121 gttgtcattg atagttatag tacagatgaa actttagaga ttttgtcttc ctaccctcaa
    15181 ctggaagttt gtcaacgcaa atttgattct tttgctaatc aatgtaacta tggtttatca
    15241 aaaattacat cggaatgggt actatctcta gatgcagatt atatcttaac tgatgaactt
    15301 attaatgaaa ttaagacact gccagtagaa gcagatatgg acagctacag cttcagattc
    15361 aagtattgtg tctttggtaa acctttacgt gggactctac ttccaccccg caaggtactg
    15421 tataaaaagg aaaaggcaat ttacaaagat gatggacacg ctcatcgggt ttcagtagag
    15481 ggtaaatcca gattgctttc agcatacatt catcatgacg atcgcaaatc cttaagtcgt
    15541 tggctatggg cgcaagaacg ttacatggtg attgaaacca aaaagctccg agaaactccc
    15601 aacagtgaac tgagtttagg cgatcgcatt cgtaaacaaa aagttatcgc acccttaatt
    15661 atactggttt attgcctgat cctcaaaggt ggtattctgg atggttggca tggtttatat
    15721 tatgcattac agcgagtctt ggcggaaatc ctgctcagca tacatttaat agaagctagg
    15781 attgataaat aattggctta attagcctac tttttcaggt gttaatattg tattaaatca
    15841 cttttagttg gagtgaatta tgatttctgg aattatcaag ggattttatt acttgctttt
    15901 aaaatatcct atgagattta gtggttggtt ttataagaaa tttatatgtc ccaaaagtga
    15961 attaaaagtt cacttaggac caggaaaatc taactatctc aatggctggc tgaatgttga
    16021 tgctaattta atcactgcca aagtggatgt atggtctaat ctattagatc ccttgccatt
    16081 tcgtaaggaa tcagtagata tcttttattc acatcatgtt gtagaacatt taccagattc
    16141 acatttaatt gtccactttc aagaaatgtt tcaggcacta cgtccaggag gcggtatacg
    16201 tattggtgcg ccgaacatgg gtaatgcgtg tcgcaaatat cttcagggtg actatgattg
    16261 gtttagtaat ttcccggaaa atcgcaagag tttaggggga agattcacaa acatgatttt
    16321 ttgtcgagga gaacacttaa cagctttaga tgaatcatat ttaggtgaaa tagctgaaaa
    16381 atgtggcttt gtggatatct catttccctt acctgtgaag gaaaccaact tgaaagacct
    16441 gggaatcagc gaagttgtct tgtcaaaaga atatgaatct gattttgctt ttccacacac
    16501 agttatttta gaagctagaa aaccagaata ggtatttatt ataaataatc acctcaacga
    16561 gggcgatcgc ctaaatagct agagttggcc ggatcgattc gggaaattat agaatacggt
    16621 agaatcaaaa ctaatttcag ttgatgccat gttgaaactg aacaaaaaat acgggtctct
    16681 aattttagca ggtttgattt tgggattatt cagcatgatt cccatccgac tagcgatcgc
    16741 ctattaccat tccccccatc cccaagctat cctcaccctt ggaggagatc cggtacgaga
    16801 acaatttacg gctcaatttg cccaaaaaaa tccccaatta gatatatggg tttctagcgg
    16861 tacttcccca aaacaagctc ttgccatctt ccaaaatgca gatattgcca accaccgcat
    16921 tcacctagat taccgtgctg ttgacactgt taccaacttt accagcctcg ttgacgattt
    16981 taagcgccag cacattcagc atatctattt agttacctcc gctgatcata tgcccagagc
    17041 caaaactata gccaccttag ttctgggtag tcaaggcata atttttaccc ctatccctat
    17101 tccgtcccaa aaccctagag aatcaatact ccgcattgtc agagatagtg gacgttccct
    17161 attgtggatt gtatcgggtc atactggagc tagctttcac cctcgctttc gtgagccatc
    17221 ttatgcggct agataaatac actctgggca gttatacccc tggcgcaccc tactggaaac
    17281 agcttttgtg gtacttcctt ggttctccct tagttgagag ttcttggctt cccatttcat
    17341 ctgtgaaggt gggaacatta cgaatttttg gagctagtat tggtcaaggt gttcgcatta
    17401 agccaggagt gcgggtgaag tttccttggc ggctaagttt aggtgattat gtttggattg
    17461 gtgaagatac ttggatagat aacctcgctg atgtgactat agaaagtcat gtttgcttat
    17521 ctcaaggtgt gtatctctgt acggggaatc ataactggag tgaccctaac tttgagttaa
    17581 aaattgcccc gatttatctt caagaaagta gttggattgc ggctaagtca gtcattgggc
    17641 ctggagttac tgttggtaga ggtgctgtgt taactctagg tggagttgcg gctaaatcat
    17701 tggcatcgat gactatttat gcagggaatc cggcacaacc aattaaggaa aggaagatag
    17761 tataacattt cttcgtgtgc tgagttactt agctaggagg aatttaggga tttctctgac
    17821 atttaaaaca aaaagtaaaa tagatgtaac tctaattcat aaattacaag caaaggcatg
    17881 aagttaccca accttgatcc ccaaactatt gatcgcatca tcgaaatggc atgggaagat
    17941 agaacaccta tggaagctat tgaggctcag tttgggctac aagagaaaca ggtaattgct
    18001 ttaatgcgcc agcaaatgaa acaatctagt ttccaaatgt ggcgatcgcg agttaccaaa
    18061 cgcaaaacaa aacatttaaa gaagcgagag tttattgcag gtagatttaa gtcacaaaat
    18121 caaaaatcct gaatatgtga cagatacggc attctcctga aaatttatct ttttgccatt
    18181 gttgctcctg gctaggggcg ttgctggggt ttttttcaga atagaggcga tcgcaattac
    18241 cgtcctgacc tccaagacct gagtttggtg atgacaggtt tttcaggtgt ggacaaattg
    18301 agtcgatatt gggttattgg tacataagaa ccattaccat cacgtatggt tacgagaaag
    18361 cctgtttgat tgtttgggtc tttactaatt ttatcgatgt aaccaagctg tatttgtttg
    18421 atatttaagg gttttgcttg ttgaaatcct ggttgggaaa tacaaacaat tggcgtagca
    18481 tctatatact gacctgaata aaaccaataa gtttgtcctt tggtttgaaa ttcggatttg
    18541 tacatcaccg taaatctgtc aaactcgtct aattgctgat tttgtttgca ggtactgtca
    18601 atatatgttt cttgagcatt ggcgggagtg ctggaaaata accccaacat gaaactcatc
    18661 gctaatgcaa ctgtgagtgt ggtttgagac tttatcatta gtttattaaa aaatttggtg
    18721 cgcgatcgct ttcaggtcac agggtattgg gactgttaaa acagttggca caaagactag
    18781 atatactgat ctctgaggca ttgagaacgc tggtgccaag tttggtaatt ccgccctcaa
    18841 aaacctcaga taattgagtg ctatttaaag cttaaggata attttatcat gtcccatctg
    18901 ccaacagcct tcacacagcg actcctgcgg ctgattacct ttgtcatctt cctcaccctg
    18961 attagtggtt tcatccttcc tgctcctact tgggctgagt cttctggttt aggagttgat
    19021 catggtcatc tgagttcttg tcccgcttcc aataactgtg ttgtcagcca agacgctgat
    19081 gcaaaacacg ccattgaccc gattacatat catgtagacc gcgatgcagc aagagaaact
    19141 ttacttaaag ttctcagtgt tgttccccgc acagaggttg tagaacagac agataattac
    19201 attcatgctc tttctaaaag ccggatcttt aaatttgttg atgatgtaga gttttatttc
    19261 ccagccaatg agccagtgat tcatacccgc tctgcatctc gcataggaga gtcggatctt
    19321 ggtgtcaacc gcaggcgtgt agagcaaatt cgtctggctt tgcgcgattt aaatatctaa
    19381 ttttagtctt ataaaatcaa atacattcaa atttttcggg gtttgggtgt agtcctctct
    19441 ggggcgatcg catcgggcgc agtcttggta gatatgcggc gggattaatg atactgtttg
    19501 agcgatcgct ttatttatta aagaattaga tttttttatt ccgcgaggat tttgatatgt
    19561 tgccttggac tggtctaatc accgctctca cactgttgct gtatttcgtg atcaccatta
    19621 atgttggtcg agccagagcc aaatacaagg tgtcacctcc ccaaatgact ggaaaccccg
    19681 actttgaaag agtggtgcgt gttcaacaaa ataccctaga gcaaatggtt tttttcttac
    19741 cggctttatg gctattctct ttctacgtta gcccattatg ggggtcggct attggtgcag
    19801 tttgggttgt gggtcgtatt gcctacgctt ggggatacta taaagcagcc gaaaaacgag
    19861 ccattggctt tgccatcagt tctctaagca gtatagtgct acttttaggt tctctggtgg
    19921 gtgtcatcct atctttggtg caatcataga acttctccaa aagacggtct ttagcaccca
    19981 gtcaaaatga ataaatttat ttatttggaa ttatgactgc tcaacgtttc attgataacc
    20041 gtcataaata acttatttag agggatttcc actgctttcg ccatacagga aattacactt
    20101 ttgggagcaa aagaacaata caaaccggct tctaaaaacc aaggttctcc ctgtgggtcg
    20161 atgcggaaat caaataaact gtagtggcga caacccaaag cctgatgaca cttcttagcc
    20221 acttcctgaa ccttttgggt aatgggatca ttcgggtcta caatccaaga cttcatattg
    20281 tctttagcgc taaaacgcaa attaccatca tcggtttgtt ggagtttatc agcataactg
    20341 cggatgggtt tctcttcagg gtctaactga tactcttcca ggggtaaacc tactaactcc
    20401 ccatcttgga caataatgcc acatcggact tcgcgaccga gttcgatgaa tgtttctaca
    20461 atcacctcat ctgcatattc aaatgctttc tgcaaagcag cctcatagtc actagcctct
    20521 ttgactaaag ccacccctaa agagttgtca gaacttacgg gtttgatcac tactggaggt
    20581 gtaattgttg gcacatctcc tgggcggagc agttctccac ttggcacgtt cacccctgcg
    20641 gcggcaacaa ttgctttagt tctgcctttg tggctcgcta ttgccatgat atccgcagta
    20701 ttgcctacgt aggggatatt cagcaggtcg aatagggcgc ggtagtaagt cattcccgga
    20761 agacaaaaca tttgtggtaa cacgaggtca atgttttgcg tggtgagaaa cttgatggct
    20821 tgaaccagag gaatcggttt ggtgagagcg atatcttctc gattcaggga gcgaggaaat
    20881 cgccactggc catcaggtgt aatatatgca atataaaagt catagcgtga tcggtctgcc
    20941 gttgctgtga ggcagtcttg ggcgtaaagg cgtgacaaat cacagtaaaa atcattgtgt
    21001 gcagacccaa ccaaatgaag gatacgaagt aatggcataa ttcatcttcc tatatacagc
    21061 agtcttcatt gagataaaca acaaatttat ctgtgttcaa ccgtggttga ttatttagcc
    21121 ttgtggagtg acaatatgat taatttcacg caaaggcgca aagacgcaaa gataaaaata
    21181 gtcttttagt cgccacctaa ttccaccagt ttgccaatat tgaaatctat ttttacccag
    21241 cctttgagtt gttgcaggtt ctttagcaaa agtaagggaa tctgccagtg atacaaagtt
    21301 aaaaatggta cagggtcatc aagttggtaa atggcatcag ttccttgcaa tagggtatta
    21361 accgatgttt gcaactgttt ccaggaacgg ataccagtta gtcgccaaat ttcgtgatat
    21421 atccagtaag tgggcttgct acttgctagg ggttcggtga ggttaggtag gggagtttta
    21481 ccaagatagg catctgccac accaggatga ttgtaaaaca ttgtgattgc tgaatgagtc
    21541 cggggattgc attcaatggc gtaaactgta ccggattcag cttgaataaa atcgaaagaa
    21601 acttgtccag tcagtgccaa actctggacg aagtgttgca cccattcccg aatttgcgga
    21661 ttttcgacgt tttcatagtt gatttgaaac gcagaagagt ttgaacaaca atgcaatctt
    21721 aattctccgt cccgcactgt actatgtgtg cataactcct taccaggaat aaactcttgc
    21781 ataatccaag ggttttctga actgatgggt aaagtgttga caaaggcgac tgtctcttct
    21841 ggggtgtcgc agggcagttt ggttaaattt aagcgacgaa cggaatcgta agcaatattt
    21901 tttaggatat atttgtgggt ttcttgacta aaatcaaaat tgatcacttg ttgaggatct
    21961 gtaattttaa aggatttggg gacagataaa ccaagcgatc gcgcttgatc agtaaaggca
    22021 aatttatcat cgagcatctt ggtaacatct gcatcgaagt ggaaaacttc gcagtattct
    22081 gataatgccg gttttgctaa agagtcgtag taactagcta caggactgca tacagggaca
    22141 taaacgtcaa ctttctcctt tttaacgatt tctacgatcg cctggatata gccttgtggg
    22201 tctgattgcg gtgcgggaac tgtataaaaa ccactgacag ctttggagaa tctatgccca
    22261 gataaccagt atttgtgacc ttcaatcagt atcactcgat gtccggctgc atggaagcaa
    22321 cgagccagtt gcaatgcttt ggtcatcttg gctccactca ctaagatagt ctgaggatga
    22381 gccgcgacga cagctttttt tctgaatggc gatcgcacaa cgccccacaa caaagatatc
    22441 aacactatca aagcattaaa cggcaaagct ataagtaata acgtcaaagt accgagagtc
    22501 tggaataaag ctactatctt taccctaaaa cccattgatg acgtgggaga ttccgccaga
    22561 gataaagaaa ttgattgtgc cataagtctt tgaaagtacg aaaagtaagg ggtagccctc
    22621 tcaaaagatt cctctttaac ctctttactc tgtgtcctct gcgtctctgt ggttaaataa
    22681 aattcttttc aaaccacgga ggcacagaga acgctgagga aaaaaggaag tttacgcgac
    22741 gcgtctaatt agggtgacac catctctgat gggtaacaaa acttgttcta cacgaggatc
    22801 ggcggcgaca acacggttga actgtgcgat cgcttcacca ttggcggtgc gttggtctgc
    22861 ggggaggtaa acttgtcctt gcaacaaagt attatccacg cagattaaac catcgggagt
    22921 cagtaactga tgctccaaaa tagtctggaa gtaatctaca tactcctttt tatcggcatc
    22981 gatgaaaatc aaatcaaatg attcttttct agctgctagc ttgtggattg tctctaaggc
    23041 tggtgcaacc tccacaatga tttttttgcc gtgaggagat gcactaaagc attcctgagc
    23101 aaattgggcg acataggggt ctacttcaca acctatgagt accccatcac tgggtagtgc
    23161 ttctgccatt gccaaggctg aatatcctgt aaacattcct acttccagaa tgcgcttggc
    23221 tttggtcatg tgaacaaaca tttttaatgt ctgtccttcc agatgtcctg agagcatttc
    23281 ctgctctagt tgacgcactg tttcgcgatc gctaaaacgt tttccccagt cttctttgct
    23341 ggttttttgc gccaatgctt ttaatgcgct cgattccggc gtagtgtaat catccaaata
    23401 gggatctaaa cctgcggcta attccactcc ctggcgcaga gaatctaata tttctgggga
    23461 aatctgactt tcttgggcta atttgagagt tttctgtagc agggctacta aaatgctgtg
    23521 tggcgttatc ggtctagctg tttcttttcc tacaatactg gtcatatctt cacaccccca
    23581 atagcgtggc ttcttgactt tcaatgtatg cgtcaacgcc ggctccacca cgagggtatt
    23641 tagcacaaag acgtttgtgt tcagctaacg cagcatcaag ttcatcacgg ttgagatcat
    23701 tgacaaagaa gcactcacca ataggacgag gcatagcggc gcgttgtttg ccgtctcgtg
    23761 ttaggctaat agactttgta gcatcccaaa gcaaatcgcc atttagtaga ggatgatcga
    23821 gagataaacc aattttactc attaagtcta gaatgcgatc gcgttcccct gtaggaatat
    23881 agccccgttg tgcagcaata gttgcagaca aagccatatc tatattcacc gcatgaccat
    23941 gatagagagg tacacgaggt gctaattcta gagtaggact ccaagtgtgt ccataggcaa
    24001 tcactcgatc caagtctaat tcatgcaagt taggagtctc taactccagc atagttttga
    24061 tagcttcgta gttgactgta tgagcaattt ctttgatttc cggtgtcgca ttcacctgtc
    24121 caaagtgagt cgaaagcagt tgttcgccat attcgtatag cagttcaaac acttgtgaat
    24181 tagacactac agcgattttt actaactctg ccatcccatt gcgaacttga gatgttggca
    24241 aggtctgcaa aaatgagaaa tccagaatca ctttcaaagg tgcatgatat gctcccaagc
    24301 gatttttcaa cttgcgatga ttaacggcga ccttaattgc tacacctgca tcaattaaac
    24361 caattaaggt ggtgggaacg cgaataaaat tgctcttgcg acggtaagca gcgcaagcaa
    24421 acccagccac atcagtaatt agaccaccac caacgactaa aactggttct ttccgaacta
    24481 aaccaaagtc ggaaaaagca tcaacaattt tttcaaagct agcaaggctt ttatctggct
    24541 cggaaataat gatcggaaat actgtcagat caatgtcata gtgcttaaaa tatgacctga
    24601 tttgcttgcc ataaagttca tagacattgg catcaatcac agtcaaacag cgaccaaatt
    24661 tcgcgtaact atcggcaatt tctcggtttt taagatcaaa tgcaccgttc acataaacaa
    24721 ggctaaaatc aattttttcg taaccttcta cgtgaaatgc agtttctgta gcttcaaacg
    24781 atgcttgaac tttattcatc tctcttgacc ttattccaag taaaaaattg tgaaatttcg
    24841 ggcttaattc ctatttagcc taatgtcagc cagtcagaaa ttatgctttt aatcctttga
    24901 gattaaagac acaacaaaat aggcttgcaa taaaaaagcg aagcttgatt actggctggc
    24961 gatgttatta aacaacgccg tttatttgat tgagtaaatt ctgtaggtgg cttcacctct
    25021 aattcgagat tacctctaaa ttagtcaact agtcccacta gcaatatttt gctaagtaat
    25081 tgcactccct ctttcgggat tgttgacact aatttggaaa atttatctga atttagatgt
    25141 attccactat gtttaatttt agtggctttc cgattgtgag atttcgtgaa actcctgtcc
    25201 tggagaaatg ttcgtatcgt ttatctccaa gctttaattt gagcttagaa ccatgattca
    25261 ctcttaattc gctgtttctt agcatgacta tcaaacctta tattgctaaa ctcgctacat
    25321 tctatttggt tcagaatgac agtggatttt gaggattttt tccggaattt tgaggaattc
    25381 cactactttt gactctagca actttccgag cattgaattt ggcaaaactc ctatgtttct
    25441 aaactactga tattgtctat ttacaagctg atatttgtga ttatcgccat gattaattcc
    25501 cagttagctg ttttttagca tgactctgaa aacattaaat ggctcaaaac gaacatggtt
    25561 gactactctt tgtggagaat gtcagtatca tttgtctctc tttcagtcca gttactaccc
    25621 agtattcaaa atcactgcct tagtagctcc tgaaaattca ggatttgaat atatctgagt
    25681 taaatgtaac aaaccttaaa gtttttttca ggaatgggcg tgtgttaaaa aaatgctaaa
    25741 tctgtttgaa ttagctttct agttctcaat taagctggtt tagcttaaaa cagcaaatta
    25801 tttgctgctc agtaacttag aagcacgata caaaacataa cattagaata atatgaatca
    25861 taacatatgt aaatcattaa accagcattt tttgcaaatg aacgcaaaaa tcaaggttct
    25921 agctcttgtg atcagcctga cagcatggcg atgagctatg ttttgcatga taaatttgtt
    25981 gttcagcgat cgctcacaaa tccgctaata ttgattaagt ttgattacgt ttaggtctaa
    26041 aagataacaa cgctcattgt aggtgctact aatcttctta gccgtgattt gtatcactgc
    26101 gaagtatcct tggtatgagt gcgcgagtgt aatttgtcaa gattcttcag atatattttg
    26161 atgcaaagta tgatgggttt tccaaaaaat tctcagaaaa tttaatttaa acattatgaa
    26221 gtggacgcat tacgtgggac gatgctagct aatgatacta gtgtctatgg tattgcttgg
    26281 gactggatga ttctcttgtt aacattaata ggcttgatcc ttatctatgg acgactttat
    26341 ctacgggcgg caatgtaatc aggagaacaa caagcattat ggaactcgat aaacctactc
    26401 agggcgtaac ttcctctgaa tgtgctgcta aagtaatgga gacagttccg ttaatgatgc
    26461 ggtttatccg agcggatatg cgagttcaca gtgctgcttc cttatcgata ccacagttgc
    26521 gatcgctagc cttcctcaac cgcaatccag gtgcttcact ctctgagttg gcagaacatc
    26581 tgggtgtcac ctgtgctaca gcatcagcaa ccacggaacg gttagtacaa cgcaacttag
    26641 tccaacgcat agatgatccc caagaacggc ggcgagttct cttgaatctg actgatgagg
    26701 gaagacatca tttaaagcaa tcccaagacc aaactcgcgc tcatattgcc gcacttttgg
    26761 atcatctcac accagagcaa attgcccata ttgaagaagg gttgggtcta ctgaaaaatg
    26821 tcttcgagcc aacagaaatt aaacatataa ataggtcgga gtaaataaag ttaactggct
    26881 agggtcgtca tttgtccttt gtcattggtc attggtgagg gtttcaggag tatttacata
    26941 taataagttt gattatccgt ttatgtctgg aatacggcac tacgtgcctg ttcctccggg
    27001 gctttcagac tgccgttaag tttttggtaa tttcaaaaag cattgtattg caaataaaag
    27061 tacaatccat tttcttgcca tgtcccttta ttgttggagt caacagatac taacggaata
    27121 ccccagtcaa gacgagccgt gaagcgatcg ccctgtgacc atcgtaaacc taaaccaatg
    27181 gcggctaagg tgttagggtc aggattttct ctaccagaat tattccaacc cacgccaaaa
    27241 tctgcaaagg gaatcacctg caatatacca ccgatgttag ctgcccgtag gattgggact
    27301 tgtacctcag ctgaagctaa agcaccattg tcagttaaca agaaattttg acggtaaccc
    27361 cgcacactac ccaagcctcc caagccccac tgctctaaag gcaaaagcgg cctggatgca
    27421 agttgcgtat ttgcacgtag taaaagtaaa gtttcagggg ctaatagacg tacccactga
    27481 gcttgtccct gccacccgaa aaagcgacca tcggggggtt caggattaat tgtggcattt
    27541 aacgccccga tacccaaatt aaattgtgac ctgagcgcaa tgacttcctg gctgttgcga
    27601 gtcgtccatt cttggaaaaa ccggaacgcg gatatgcgtg tacgtccggc ttcatcagct
    27661 cccagggaaa ggaaaggtat gcgttctgct tccagataag aggcttcact ttcgatgcga
    27721 gaagctgtca caccaagggc aaattcctgg gtgggagttt ggactaatgg ctggcgaaat
    27781 gtcaattcgt agtagcgaga agaagattgg atatctagaa cgttgaaagg acgttcaatc
    27841 acattgccag aggcagtacc aaagttaaaa ctgagtgttc cgttgtgagg attgaggggt
    27901 agtcggtaac tagcatctaa ggcattgcta ccatcggtgt tggtataagt tacattcaga
    27961 ccatctccta ttcccagtaa gttagcttcg ttaaattgta acctccgccg gaaactacct
    28021 acggctggcg atcgcccatt atctaaaact acttgggcgc taaaggattt cgcctcttta
    28081 atttccactt gtagcagact ggtattgggg cgcaaccctg ttgacagttc agccgacaca
    28141 ctttcgatca aaggattaag ttgcaaaagt tgcaatccct ccaataaacg ctcctgattc
    28201 aaaggcgggg tagtggcgat cgccagacgg ctacggatat aatcggggtt cagtcgctca
    28261 gtcccactaa ttttgatatc ctccaattca ccttccacca cctgaatttt aatcacacca
    28321 gactcaatct cttgaggtgg aacataagcg ccagaagtaa tgtagccctt attgacgtat
    28381 agttgtgtaa tttgagaacg agcctgaaaa agttccctca tcgtgattgg ccgtttagta
    28441 aactcagcca cagcttcagc taactccgac gcactaaata ctgtactgcc cagaatttca
    28501 aacctttcca cagtaatagt ttcagccgcc tcactgggga atacatcttc tggaatggaa
    28561 cttggcagca aaggtggaag taagtctact ggtggcggta atagcggttg tggtgttggg
    28621 agtggcgcag gtgaaggtgg ttggatatcc tgcggcggcg ggaatctctg ggagaagatc
    28681 aaattttcct ttagtacttc ttcggcttga acaggcagaa gtccaaaagt gatactccta
    28741 agtaaaaata tacttacaag cagccaaaac aacagagatt ttttgcgagc atcccaactt
    28801 ggtaaaaaca taaaatactc atacaaaaaa cctattaaaa cctctttcct tggcgttctt
    28861 tgcgtcttgg cggtttgttt attcatattt ttacttcaaa accaattacc aactaacaca
    28921 taggcagccc agtaaccagg gcgacgataa ttaggatagt tggttaataa ttttacttga
    28981 gcgcggcgca aagcttctgc tttagtcact ttatgattaa ctaattcatt gtaaaattcc
    29041 ccaattaaga tcgcagtaga ttgatcattg atgtgccaca gtgaagcgat tgtgctgcgt
    29101 gcgcctgctt ttatagctgc accggctaac cctaatgtag cccgattgtc acctgtggca
    29161 gtttggcaag cactcaaaac taataattct aaaatttgtt gactagtgtc gctctgactg
    29221 cggagcaaat tatcgaactg tagaacattg atagtaccat cattcgctaa aataaaagtc
    29281 tcttccgggc gagaactaaa ctgcccatga gttgccaaat gtaagacatt aaaaggcaaa
    29341 gtagtgacat tgctttcgag agtgctgctg gtaaagtctt gatctagtag ttttttggta
    29401 gatgctcctg tttgagcaat caggtcaaat tctaacttga ttcctggtaa agctgagaat
    29461 gtggaaaaac ccggaggtgg ttccactaaa ccagccgcga gtacattcag tggtgtttca
    29521 gccagaggtt tgggagttaa tagcccaagc cctaaactga gagcaacagc gtatttttct
    29581 accaaatatt tctcgccgtc ataaagagca gctaggggaa tatttcttaa tgctccgtct
    29641 aaaacgaaga ccaaagtatt aacttgattt gtggtgaaat cagattcaat aggtttaatt
    29701 aaccagttat agacttcttg ggaaaggact tgtacttcct ctgttctatc tggttctaaa
    29761 atatattccc gcagttctgc caaagtgcgc tcaacttcaa cctgggattt tttaactgta
    29821 taatgacgca gtggttgttg aggaattttg acaattactt gaagttcctc tggcagaata
    29881 attgggtaga ggatggcagt gtggggattt tccttgtcta ctacttgatc taaaagcact
    29941 ttctgtcctt ctaaacaagc ttctcggaaa aagttatcta gttctgctaa ctgtaaagcc
    30001 tctatccttg ttctagcttt atctaatgtt ttaacgtttg gtttttcgtc tgaattttgc
    30061 agcagcaaag ccaccgattc ccgataaact ggctctacat tgtcgcggaa attaaactgg
    30121 atattttgat tgactgctac taagtcagta cgtagagact ctaatgtttc tatagctgca
    30181 tcataagcgg cgatcgctcc ggtaaaatta ccttggtctt tgaataatct acccatctgc
    30241 cattgccaca aataagcaat ttccagcgcg ttgctagttt gcgctaacat caaagcctgt
    30301 tctgtcaggt taatagcctc agtaaattgt tgtgtttttt catacaaagt ccccaaattc
    30361 cctaaagcat aggcttcggc gcggatatca tccaaactcc gggcttgctg tacagcagta
    30421 gctaggagtt gagcaatttg ggatgtggga gtatttaaac tacccaagct gtgagcaaag
    30481 ttaatgcggg cgtaaatcga tgggcgtgaa ggtggaagtt ctttcagctg agattgaagt
    30541 tcgggaatta aaatttgggc tgctgcaaat tgtttttcct ctatgagtaa attcagatga
    30601 ttgagtcggg cttgaacttt tgtcagaggt gaaggtgaga tttcaaacgt ttgctgataa
    30661 aatgcgatcg cctggggtat tttttgttct atctgagcat tattacctaa actgagcaga
    30721 cttaaagcca tattttctgg tgaattaagt ctttggtaaa ttgctaaact ttgttctaaa
    30781 gccagacgag atttttctaa ctcgcccaca ttctctaatg tatcacccag cgaaagcaaa
    30841 actgctgcct tcgccaaaga atcatcctga gatgctaaag tttgatttac ctgttttacc
    30901 ttctcaatag cttgcttatt aaaaccttga ttgcgtaatg cttgaacttg ataaattata
    30961 gccaaagccg caccattttt atcgccgagt ttagtgtaaa tatcttcagt ttgtttccaa
    31021 gtatccagag cggcttctag ttttcctgtc aaaagttgta agcgcccttg gatatctaga
    31081 ctttgagcta aaactgctaa atttgtattg gttgtgcctg cttgttgaaa tccttgtaaa
    31141 tttaagctgg tattaatagt taattgcgct tgttgccaat caccaatttg ttgataagcc
    31201 agtgataaat tgctcaaagc tacagcttgc tttaaagtat ttccctgctg ttgatattct
    31261 tgcacagctt gttgtaaact ctccacggct tcggcaaatc tgccagtttc atataatatt
    31321 tggctttcag caatgttatt ctgtgaatca aatgatagaa tttcactttc agaaatatta
    31381 ccccaagccg gagtcaccaa aatacatata catacactta gtaaaaccaa taaacaaaaa
    31441 tttattaact tacttttttg atatctttga tttttcacca gtccccacac ctcctaaaaa
    31501 gaaatcaaaa aatgaattta tagcaaacag agacactcca gatgcagaga gacagaatta
    31561 aataaagact cataaattct tggcgttttt ggcgacttgg cggttcgata ctcctaaatt
    31621 aaaaacgtaa aatttcccgc tcatattctt ccggtaaagg cgtaacttcc caaactaacc
    31681 cttcaccacg ttctaacatc acttctacat acaaattttc tacaggcgtt gtcgccgtat
    31741 cttcattgtt gggaaatggt tgtaagtctt ccgtgagtag tctgagttgc aaccctacag
    31801 gaatcatatt ttctgaattt gcattgcgta attcaaagcg ccaaatttgt tcttcgggat
    31861 tgcctttagg aaaaactcgt aattcataag tatgatcagc tatgagtatt tggcgagata
    31921 agcctaaaat agaagtttga ctttctcgac tcctcattcc tgaaggcaaa gctgtaaatt
    31981 gtcgtatttc ccagcctagt tgttgagcaa aatttgatac cccttcttga agccattgcc
    32041 cgattgatgc tggttgtgca actccttggc gcaattcata caagctttgt cgccaaccgc
    32101 catgagcgat taatgcaccc cagagaggaa agggaacttc taaacgagga aatttgattt
    32161 ctgcgttact taatctttgg agtaaattgg ctgcttgagt ttggggtaaa ggtggtaagt
    32221 cagtcaccga tgcacgtcta atttcttcag catataattg gtgagttatc caaagcacat
    32281 tcaagtctgg gatgagatga tcagattcta aactgtaagt gcgatcgcct ggatcataaa
    32341 cccccagagt tttcaattgt tggtgagttg tatagcctac aattctgatc cattcctcat
    32401 caggatttac ctgtaccgct aagtaataat cagccaccca ttctggaata tccacccatt
    32461 cttgaggtac gcgcaactca tccacatcca ttgctaaggt aggaagtaac accaagcggg
    32521 agttatcaaa actcatcgct gtaccattga ctatttccca aaaactcggt aaagcagctg
    32581 tattgggatg cactctcgca ttgggtgtaa tttccgcttg caaccaagct aaaaatgtcg
    32641 ttaaacaaat ttgattgatc caagcacgct gatcaccacc aggggtagaa taattatgtt
    32701 ctagaggttc tgatgtcgga accatttcta gaaccaattc atgatcaaca gcgaaagcaa
    32761 cagcagcatc aaacataatc tcaagcggtt ttactttaaa ggtgggtggg tatggctata
    32821 ataatttttg agccattctt ctagactttt acttattgca tccactacga cgggtgtagg
    32881 cgagatatgc aaatgatttt gactccactg cgttagggta gtgagtaatg agcgtttaat
    32941 gctgctaagg cggcgagaga ctgtatattg tttaatttct agctgttcag agatttgttg
    33001 ttgagtcagc tgttgctgat aataagcttg gagtaatttt tgagcctgaa tatccaacgc
    33061 tgctaaagca tccatcaaaa cttggtttaa ttgggcttgt tgtgtttctc tggttgtaga
    33121 ctcttcttgg gcaataattt ctgtgagtaa ggatggtggt aactctgcgg gtaatgtatc
    33181 taatagatta cctgagtctt gcccctgaat cggagcatct acagacacaa acttggggta
    33241 aagaaaatca cgcaccgctt tagcggaggt actcagccat ttttccaaag tttctggagt
    33301 cagttggctt aagctttgtc tattgtacaa ctgagtcatt gcttgccatg tagcagtatc
    33361 cggtttccct aattgacgga tagtttggct gtcactggtg tagagttcct taaaacattc
    33421 ccaagctaag acgtaattat tgataatttg actattaaaa cccgcattcg ttaaggaatt
    33481 tcccagccgt ttgcgactaa ttttatgcag taaagcccaa tctgtgcaga tatccgcttc
    33541 ctttcctaga cgtaatgaat ctttgaggaa acgctcaaaa gcatattctg catagctttt
    33601 taaatttgta ctgtattcag gattaaaatt tttgagaatt ttataaatgc aggaaatcgc
    33661 catctgaaaa caatcagcga tagaaaattg actgataaaa tttacggcga tttttctcga
    33721 aacccaataa cagacttctt gtaaataagc cgaaatatgt cccactgcta tggggttaga
    33781 ttctatttgc cagattttgt accaataaag cacccaaaaa ttatcagatt gctgttgggg
    33841 gtattgttct aagcatcttt tgatacttcg ctggagtttg ctatctgtag cccaaacgtt
    33901 gaacctatct gcatccaact gcacaaaagt ggagaagatt tccgtaatgc tctgtcgggg
    33961 ttgcataaat attttgtgag tatagaaaat ttagaggtta cgaatttcta cctaattgta
    34021 atatacagga ctgcggggga agcaaaagtc aaaaattgac cctgagcgta gccgaagggt
    34081 aaaaagtgaa atgcttgctg tgaataggtt ttggactttt gttatgtcct aaccgccaag
    34141 gacgttgcta tattttcgac attttggaaa aaaatttttc tcccaggtgc ataaacatat
    34201 aacgccatcg tatacagcca cagagagacg caagcacagg ttaatacctg aaagcccagg
    34261 tcaatttatc acaatcatta ccaaatatca aaggaaaaaa atcatgtcta atatcgatat
    34321 tatccgcgct tggaaagatg aagactatcg caacagcttg agtgaagaac agcgttccca
    34381 attacctgaa aatcccgctg gactcatcga actacctgat gaggagtccg atgctttgtc
    34441 tggtggttgt tcatatttta caggaacttg tggacgtgtc tgcgcggtac tcacacctag
    34501 atatggctgc acaatctgtg gaggcggagg tttcacatct tgaggtagtg gaatcgagaa
    34561 cctaaatagc ccatttcggt atgcgatgtc tacgcctgtc gcaggcatcg caactttctt
    34621 aagtaatctt actgtagcac taagaagatt gggtaggcga tggcttgccc attttcggaa
    34681 atttccaata gaccaggact tacgcaacaa ttgccaaaaa tcttgattta tcgaaccgcc
    34741 aagccgccaa gaacgccaag aaaacgtaga ttatgcgtaa gtcctataga catctccaga
    34801 aaagaattag agaagttcca tggaacgtct ctacaagggt tatagaaaac gcacatttaa
    34861 ttctcaccag atgtctaatg agataatttc atttttgttg atgcggcaat tgggcttttt
    34921 ttgatttttt acaaatattt cattggttat ttttaaggaa aaaattatgt caaatataca
    34981 gacaatacaa actttagaat ctgaagaaat taaagtaaat tcagataata caattaatca
    35041 gccaattaca ttatgttctg cttggtatca agctataaat ttatcggagc ggataacatc
    35101 cttatctcta attcccaaag atttaagttc tagaaaaatt aatgctgaat ttgcggagcg
    35161 tcatgtacag cgatggaagt ctttacctcc gttttctact gattcttatt tcgcgcaacg
    35221 tctagcaatc aatggcataa ctgaggcgga atttattgat ttactgggtg aatcaatgga
    35281 ggcggtacgc gatcgctatc ccaatccccc aaaatggtta acagatacaa ctttagcctt
    35341 ttctggccat ttaccgcgac acaatccaga aaatcaaaat tttttagatg cgatcgctcc
    35401 actaatcctc caaggatgcg atcgcctgcg agccggaatt gcatcactga ttgaaacaca
    35461 atctcacctc ccttttgttc ccagcactat tgtagaagtg ctttggcaaa atctgccaga
    35521 aaagttactg gggatgttaa ctccaacaat ggttttggaa ctgaatgtag cccgcctcca
    35581 aggaaatctc ccaggggaaa catccgcagc cagattccac agctttttag aacatttatc
    35641 ccagcctgaa aacacactaa atctgttaca agagtatccc gttttagccc gccaactagc
    35701 aacagcgatt gaacagtggg taacatttag tttagagttc ttacagcact tatgctctga
    35761 ttgggaaaca atccaaaata cttttagccc agacaacgat cccggcttgc tgatcggatt
    35821 agatatgagt gtaggcgatc gccataaagg tggacgcagc gtagccattg ctcagttcag
    35881 ttctggtttg caactaattt ataagcccaa atcattagct gtagacattc atttccaaga
    35941 attattactc tggttaaatc aacacagcga tcttcctcca ttccgcaccc tgaaagttgt
    36001 tgatcaaagt acatacggat gggttgagtt tgcacaagta caaaactgct ccaactcagt
    36061 ggaagttacc cgattttacg agcggatagg gggatattta gcgttactgt acgttctcga
    36121 agccagagac tttcactttg agaatctgat tgcatcggga gaacatccca tattaattga
    36181 cttggaagca ctttttcatc cccgaattga tgaatcagaa cacaacaaag taaatcagta
    36241 tgctaacagt atcatgtacg attcagtttt acgggtcgga ctcctaccca atcgcgtctg
    36301 gtcaaaccct gagtctggag gtattgatgt cagtggttta ggcacgatcg gcaaacaact
    36361 aacaccagac cgtcttcctt actgggaagg tgtaggtaca gatgaaatgc agttgaaacg
    36421 ccgacaaatg gagatggttg gggagcaaca tagaccaact ctgaatgggg ctgaaatcaa
    36481 tgctttcgat tatacagaat ccgtaattac tggatttagc aaaatttatc agctgttgtt
    36541 acaacaccga gagcaactat tagcagaaga tagcttgtta agtaggttcg ctaacgatga
    36601 agtgcgggtg attctgcgtc ccacacggac ttacggatta ttactcatgg agagtttcca
    36661 tcccgactta ctccggaacg cactggatcg agattgctac tttgacaggt tgtggatgga
    36721 tgtcaaaaat caaccagaac tagccagaat catcgctgct gaacaggagg atttacacaa
    36781 tggtgatatt cccatatttg tcacccgtcc tcactcccta gacctctgga gcagtaataa
    36841 cgtctgcatc cccaatttcc tcacagaagc cagtgggatg gtagttagac gttccttaga
    36901 acaactcaat gaaactgatc tcaaacaaca actctggtat attcgggctt ccctcagcac
    36961 cttagctact gatgtagagc gagtagaacc caccaactac ttttccacaa agccccaaac
    37021 tgctgcgaac agggaacagc tgttagcggc ggcgcgagtg attggcgatc gcttagagga
    37081 actagcacta ccggacaaag gtaatgtgac ttggattggt ttgacaccga ccctcaccag
    37141 ccaattatcc ttaattccct tggggttgga tctttatggt ggtgttgctg gggtggcact
    37201 tttcctcgct tacctcggtg atgttaccaa agaggaacgc tacactcaac tggcagaatc
    37261 ggcagtcaag acattacaaa agcagaccaa gttaggtaaa tcttttctca agttcgttgg
    37321 tggctttagc ggatggggag gcgtgatcta taccttgact catctgagtg tattgtggtc
    37381 acagccagaa ctattaactg aagctgaatc cctgctggaa attctcccct ctgcgatcgc
    37441 tcaggacgaa caattagata ttatcggtgg atcagccgga tgtattctca gcttagtcaa
    37501 tctctatcat tctcaccctt gtgaaagcat tattcaaatc gcccgtcaat gcggtgaaag
    37561 gttgctgaca caggcgaaat caatggcaga aggcatcggt tgggtggtgc atcacgctgg
    37621 tacaaaacct ctagctggtt tttctcacgg tgcagccggg atagccttag cattgctgga
    37681 attagctgca ttcacagggg atacacggtt ccgtacagcc gccttggatg cgatcgccta
    37741 cgaaagaact ctatttgata tccccgaagg aaattggcta gatcagcgcg acgtagagag
    37801 tccaggccaa gccgttaacg atcatgcctt tatgacagcc tggtgtcatg gtgcgccggg
    37861 aattggatta gctcgtttgc gcggtcttcc acacctcgac aatgacaaaa ttcgggcgga
    37921 aattaacaca gccctgaaaa acactcttgc tcagggattt ggtagcaatc attccctctg
    37981 tcacggagat ttgggcaacc tcgaattact attgcaagcc agtctcaccc ttgacgatcc
    38041 tcagtggaaa actgaagttg accgcctagc tgccgtcatt ctcgaaagta ttgaccaaca
    38101 aggctggctc tgtggtgttc ccttgggagt ggagacacca ggactaatga ccggactagc
    38161 aggtattggt tatggattat tacgcctagc agcaccccag gatgttcctt ccgtactaag
    38221 tctagaaccc cctcacctga acagccaagt atagaaacca atcgagtctg ccacactacc
    38281 ccataactaa ccatgaaatt ccagctgatt caacaacaaa gtgaagaaga ctgtggcgct
    38341 gctagtctgg cttctgttgc taaacattat ggtaaaacct ttagcattag ccgatgtcgg
    38401 gaagctgtcg gcactagaca gcaaggaagt tccctcttag gattgaaaca aggcgcagaa
    38461 gctctgggtt tcaatgccag agccgttaaa gtcgctctgg aactctttga tgaaacaacc
    38521 gttcctctac cagcaatcat ccactggaaa ggttatcatt gggtagtttt ctatggtaag
    38581 cagggtaata aatacgtcgt tgccgacccc ggtgcaggca ttcgttattt agaaaaaaag
    38641 tggtttctag aagcatggag caatggggcg atgctcctac tagaaccaga ttcagtccgc
    38701 ttttttactc aagaagatca acaagaaaaa attggcggtt tgggacgatt cctgcggcgt
    38761 gtttggcctt atcgtgccat tgttggacaa accctgttgc tcaactcgat tttaggtctg
    38821 ctctccctcg cttctccctt tttgttgcaa attctcaccg atgatgtgct agttcgcgga
    38881 gacagacaac ttttgacgag cgtggtaatt gctgtggttg ttatgcagct agttaccagt
    38941 agcctacagt tagcacaatc aaatatggtc gctcactttg cccaacgtct gcaactaggg
    39001 ctaatttttg aatttgggcg acaaattctc cgcttgcctt taagttatta tgaatcccgt
    39061 cgcagtggcg aaattgtcag tcgcctagaa gatattcaac aaattaatca gttaatttct
    39121 caagctgttg tcagtctacc gagtcagtta tttatcgcct tagtttccat gagcttgatg
    39181 ctgttctaca gtataaaact gacagctgtg gctggtgcga tcgctatttt aatgactctt
    39241 tccacaatcc tttcactgcc cactctccag caaaaaattc gcagtgtttt agtcttatcc
    39301 tccgaaaacc aaggcgtttt agtcgaaacc ttcaaaggtg cgattactct caaaaccacc
    39361 gccgcagctc cccaattctg ggaagagttc cagagtcgat ttagtcgcct cgctaacctg
    39421 agcttccgga ctattcaaat tggtattctc aacggcatat tttccaactt agtctccagc
    39481 atcggcagta ttgccttgct ctggtttggt agcactctag tgattcagca ggaattatct
    39541 attgggatgc tcttggcatt taacagtatg aatggtaact ttaccagctt tattaaaact
    39601 actatcgatt ttgtggatga atacacccgt gccaaaactg ctacccaacg cctcacagaa
    39661 gttattgacg ctacccccga aactttagat catagccaaa agccttgggt aaaagttcaa
    39721 agcaatgcag acatcacctg tactaacctc aacttccatc atccaggcag aatggaactg
    39781 ctgcaagatt tctccctaac tattcctggc ggtaaagtaa ttgccctgat tggtaaatct
    39841 ggttgtggta aaagtacctt agcgaaatta attgcaggtt tatatcccct ccagtctgga
    39901 aatattcgct ttgggattta taatctccaa gacctggctt tagactgctt ccgccaacaa
    39961 gtggttttag ttcctcaaga agcgcacttt tggagtcgct cgattatgga caacttccgc
    40021 ttaggttccc cggatattac cttggagcag attgtgcaag cttgccaaat tgctggggct
    40081 gatgagttta tcagcaacct cccggacaaa tatcaaacgg tgttaggaga atttggtgct
    40141 aatctctctg ggggtcaaaa gcaaagatta gccattgcta gaggaattgt gaataaccca
    40201 gccgtgctga ttttagatga atctactggc gctcttgacc ctgtgagtga agccgaagtc
    40261 ttaaaccaat tgctgactca tcgccaaggt caaaccacta ttttaattag ccatcgccct
    40321 aaagtgattc agcaagctga ttggattgtg atgttagaaa aaggagaact gaaaattcaa
    40381 ggttctccag aagttttatc tcagcaagtt ggggagcatt tagactttct cgacggtgtg
    40441 gatatatcga gagtcaatgg tttcaccaaa aatcccgcta actttcattt gaatggaagt
    40501 tctgcaatca gcattcgcta atctctaccc agaaaactat tatggttaac cacattaacg
    40561 cagactctct gcccatagtt gaaagtgatg aatttctgcc gcccattggt aattgggcaa
    40621 gattaggcag tttggtaatc gtcgctggtg tggggatagc gatcgcacta gcttctgtga
    40681 ttgaatataa agtcaccatt aaaggcgaag ccagtatccg cccgatggga gaattacgcc
    40741 ttgtgcaagc agccacggaa ggtcaggtaa caaacatctt tgtgaaagaa aatcaagccg
    40801 tgaaaaaagg agacgtgctg gctactctcg atgattcccg cctgcaaact caaaaaagtc
    40861 aactgcaaaa caacattcag cagacacaac tgcaattact acaaatcgat gcccaagtta
    40921 aagctttaaa tcgtcaaatt caagcagaaa cacaacggaa tagtcgtgca gttatttcgg
    40981 ctcaagcctc gctgaatcgc gcccaaagga attatcaaga ccagcaaatt aatgtgaaat
    41041 cccaagtaga agaggctgaa gctaatttaa aaagagcgca aaatgagtta actcaagcac
    41101 aggtgcaact gcgttcagct cgtgctaact tccagtcaac agaggcggcg atgagcgcag
    41161 ctcaagctaa acgcgatcgc tatcagaagg tagtgcaagc aggtgctttg tctctcaatc
    41221 aattagaaga agtgcagtta gatgtggctc aacaacaaca cgcggttgaa gtgcaacgag
    41281 ctactgtgga ggcgcaacaa caaattattg cccagcaaca acaatctgta gccgcagtcc
    41341 gagcgcaact gcaacgagtt gaagccggac tcaatcccag tgatgccgaa attgcgatcg
    41401 ctcaagagac tattgctcaa gaaagtgctg gcggtgaagc cactctcgcc atcctcaacc
    41461 gagaatggga agctttgttt cagcagagga ttcaaatcaa aaatcagatc cagcgtgaca
    41521 ctagcgaact acaacaagta gaaagcaatc tcagtcaaac caaaattaca gtcccggaag
    41581 acgggattct ctctcaatta aacctgcgaa accctggtca atcggtgcgt gtgggtgaag
    41641 aaattgctca aatttttcct agcaatgcgc ctttagtgat caaagccgcc gtctccccta
    41701 atgatgtgag taagttggca aaagatcaaa aagtgcagat gcgggtttct gcctgtcctt
    41761 atcccgatta cggtactctt aaaggtgttg tcagtcaaat ttctgaagat acggtcaaat
    41821 ctccaggaaa tcagaatgtc tccacagtcg ccaatgcttc tagttccatg cagggtggtg
    41881 caagttcttt ctacgaagtc acgatactcc ccgaaagctt tttcttaggt aagagcaacc
    41941 atcagtgtac tattcaacca ggaatgcagg gaagagctga tattatttcg cgctcagaaa
    42001 cagtcctgaa attcctgctc agaaaagcta ggttaattgc cgactggtag tatgatgtcc
    42061 ggcaaatgac caaaaatata gatgtaggtg tataaatggg tgcgatggtg cggagcgatc
    42121 gcactaggcg atcgcaatgc caaaaattag aaaaactcag ccatagatca atacagttca
    42181 gttaagcaat tttttccttc tctttatttt ctctctgtgt cctctgcgcc tctgcggttc
    42241 gttaaaaaaa ataaaattag ccttaactga accgtattga gccatagatg accatctcat
    42301 aaagatgtgt caaattaaac actctctaca tcgtaggata tttaattttc aggtacaggg
    42361 ttttgtccag caggtaaatt attcttcaaa ctgggttggc aacaattaat taatggttga
    42421 ttagctattt cttctaagcc agccgaatcg agtaaagttg tccactgtgc taagaaagtc
    42481 tcattttggg gattgctaaa gcgtaattct gccaaactca taatagcatc ataccaaaca
    42541 ccatttgctg cataaagcgt cgcctgttgt ggcaatgttg cttgttgaag ttgtgctgtt
    42601 aacgtggaat tttggttaat cctttgcacc caaccatcgg cataatctag tttcgtcggt
    42661 tgtttttggt cgcattgaac ccgtacctta aaaaaccagt gatacatttt tcccacctgc
    42721 aatgaggctt cacttggggg taaattaacg ctaataattc ctggtgattc tggtggtttc
    42781 aaagaagttc gatacaaagt tttacttttg ttttccgttt gctcttgcaa aacaaactcg
    42841 atgttagcta tagatgaggc attgtaggga acaaaaaaca agaaattagg attttcagtg
    42901 tttgttaaac cccaaacttg agttatggga acaaccgctg gcgtaccttg gttcagagtc
    42961 tgttgatagg tcggcactaa ggctgttacc gtttgattag ctgcgtcgca tccacggctt
    43021 gcagccccac ttctcgaacc tgctgcactt cggtctggtg gtggtggtgg tgggataaat
    43081 tcgattgagg tcagatgatg attaattggt aacgcctgga gttgtaaagg ggaggatatg
    43141 ttactaatga atgctatgct caaagctata gttaattgca ggtttttcat aattcgttgt
    43201 taagcaaaaa aatagtttta taattttttg atcggcttga tcacggctac taagatgaca
    43261 gcactacctc ctaaagcgat cgccgcaggt acgaagggaa cccaacaact atatagtatt
    43321 aataatatca ggcaaaaacc gtataaactc agaaatgcca ccccaaccgc caagcctaaa
    43381 taagcgagtt gtcgcagata aaccaccagc aaaccccctg tcatcgccca aacccaaacc
    43441 caaatcactt ccccccagac attccaagtc cataacaaag gtcgcccatc caaagccgca
    43501 ctcaacaact gactcaccat ctgtgcttgt aaataaactc cggctatttc ctgtggctta
    43561 ccttgagagg aagcataggg agtcaatgaa taatcacgaa agctttcggc tgttgtgcca
    43621 attaaaacta ttttgtcttt gactgcatcg gcttgtagtt gaccagccag tgcttgttgt
    43681 agggtaatgc ggggtgcgat ggtcaaagac cgaccggagg tcatcgcttc taagttcgga
    43741 aaggagcgat aattgagtaa aatttggtgt cccaacgcgt caataccttg gtagcctccg
    43801 gtatgagcct caattggttt taaggttagc ttacctaatt gccatgcacc atcagggcta
    43861 aattgtaact ggattccttc agcatataaa taacgtaatg tcaactgcac atttaaggca
    43921 taaggtgcag tacagggaga tgagggaggg ggagttaacg ccaacagatg ccggcgtacc
    43981 acatgatcag catcaatcac aatatcactg aagccgagag agtcagggga aacttctggc
    44041 ggtggtttga tgcctggttt gctagcttgg gggttgctaa cttgacatac tgccacaaag
    44101 cgatcgcttt ttctcatccg ttctgccaac attggataag ctggctgtac agcataatct
    44161 cggtatatat ccaaaccaat cacccttggt tgatatgcct ccaattttgc taacaactga
    44221 tccaaagctt catctgataa agacccccgt ctattgtcag attgggcttg tacatcttct
    44281 tcagtcacag taattaccag tatgcgagaa tctggttttt cctggggacg caaacttagc
    44341 aagtgatcaa acgccattaa ctcccatgat tgcagtaaac ccaaataccg tacccccatt
    44401 aacaatggtg tgatgactat gctggcaagg atcaccgcag acaaagcttt tcctaagttc
    44461 acacctcccc tagtggagat tttaggtaca gaagatattt gctgaatact ctggttgaag
    44521 tgtaattctc gccacagtag aggcatcgct gcgggatttt gataaattac aggcaaccaa
    44581 gtcgcacagg gaaattgact ttctagccct tgcaaccgtt cccgcgcttc tctgactgct
    44641 atgtataaag actcaccacg agcaaaagct tctaaaaagt acttcaggaa ttcttgcgcc
    44701 acccgatcag gaactggttc ccgcatcaca atgatttggg gtatatgcaa atcggcaaac
    44761 tcccgcgcca aacccaaacc atcacaagaa ttaaaaattg ccaaatgtaa acctcgttcc
    44821 actgcttttc gcaaggcgta ctttaactga ctaattgtca aacactctgt ttgattaaga
    44881 tcaattttgc cttcattccc gcttttatca gtagcactat gtccggcgaa aaacaaaatc
    44941 tgccagtctt gttcccatag ctggtcagtc aagtctttgc ttgatggctc cactaagaag
    45001 gtagtattag catgaggtaa ttcttttaaa agctgactat ctgtttggat atcaattccc
    45061 tgactattac ccaaaattgc taaaaccttc acctgcaatt gagggggtga gttgcggcta
    45121 acttgttcat aacaaggcgc actcagagcg atttcggctt ggggatagcg ttctaataaa
    45181 tcccacaaat gccaaggcag tttttgcaat ctcaggtcat tggtttgtag tagtatgcgg
    45241 atctggtctg acggtagcag tttttccagc aatttttcac ggatagggcg aaaactagtg
    45301 gatgatagcc aggtatttaa gtgaaatttc aaaacatccc cagccttttc gcaatctacc
    45361 agagaaggag tttgtggcga tcgcttagga ataccaatgg ggcgaccaga aaatttcagt
    45421 tgacagtaaa tagactgcca ttgatggtaa caaagaggaa tatctgagtc tggtggtaat
    45481 tcgccagtaa tttcgacaac tggtcgcaca ttttcatcac caatttgtag cgttacagga
    45541 aaccccgcct caaaactgcc tgtacctaac tttaaaacta ctaacttgct caacgtcagt
    45601 actccacata tggcgatgta acttaccgtg agttagataa cctctcccca acccctttcc
    45661 gacgcgaaga atggtttaaa tatctttgaa tttcaaggaa aaatcaaact ttgaaagcct
    45721 ctctccttct aggctatcgt gtacacacat cctgaactaa agagattttc cagttctgaa
    45781 aacagaattt aaccgaaaat ccagttcccc tcctcgcttg cggggagggg ctaggggtgg
    45841 ggtcttatgg cagaaaaaag caatttcccg acttgtgtat acaccgtagc tccttctagg
    45901 ggagaggttt ggagaggggt tttttccatc cgtcgaactc acgttacttt agtacaaaat
    45961 cagacactac tatatacgac tgcgatcagg atctatgcaa cgaatgagcc ataaattaat
    46021 caaccgagca aacaccacca gagacagata aaccacgagg ggtaatattt gggacttgag
    46081 ctactagaga tacattaccg tttttatcga caatccagcc ttgcgcctcc actattttcg
    46141 gtgcggaaga tagaagactt tcattgctca catgactatt ttgatgctga tttatcgtat
    46201 ctaacgtgat ccatcgtgct gtagatactt caccttggaa tggttctata ggactgcggg
    46261 caattccgcc ccgtccggtg acagtgaaag aactacgtct agcagaactt ccgggattac
    46321 aactagaaac aatttcttgt gacacatctg tgaaattatc cggcaactgt accaaaccgc
    46381 gactaggatc taaatcaggt gtattaactg tgactgtacc tgttaagcca aactgggaac
    46441 tagcatcaat atcgttggta ttatttcgtg gagttgataa gcgttcttct agactaaaaa
    46501 taccacgagc attaatatca accttgccac ctcgcccttg aaaagcatta gcagtgatat
    46561 cgttattttc attagggata gcaacaataa aaccatccgg tgcatcaatg aagatgttgc
    46621 caccatcacc accagcccca tcaatacctg cggtagttga gatttgatta ttgcggcgta
    46681 ataacaaaat atcgtcgatt ttgagccgaa tatttccgcc ctgacctaat ctagttgtgg
    46741 ctgagatcac cccttttttg tctagcaaca ggttacgagc tagcactttt aaatcacctg
    46801 catctcctcc tccctgatta ttcacagcaa tttcggctcc atctcgcagc gttaacctct
    46861 gggtttcaat tctcaagaat cccgcattgc cggcaccttg agagccagta aacacaccgc
    46921 taggaaaccg ctgacccgac tgatctcgaa aaaacggtcg attgggaacc tgtggtactg
    46981 tgccaacgag ttcaattgaa tcatcagctg tgatagaaac atttccacct tgaccgctac
    47041 taaaagtccc agcgcctatt tgcgctcctt ctgcgacgat taatcgatcc gtgtcaattt
    47101 taatttcgcc tccgttgcct ttaccgcgag tagccgcaaa cacaatagtg ggagagccat
    47161 tatcagcagt gccagttaat tggatctcgt cagcctcgat gttaatgctc cccccctggc
    47221 ctgtactgtt ctcaaaaaca gctgctaaaa tttgcgctcc gttgctagcg aaaaacctgc
    47281 ccgtaatgac tgtcaccgta ccgccttccc catcaccttc ggtctgtgct gtcaaactgc
    47341 tcccaaaacc aattgctgtc actgactcta aggcatttat gactatatgg cctccctcac
    47401 cattattagt agttatggca gttacttttc ccccatccag gagaatcagc ttccctgtgt
    47461 gaatctctac atcaccagct tttccagtcc ctctggtctg tgcttccaag gtactggcaa
    47521 cattcgtatt ttggtcaatg ccaatcactt ggactgactc cctcgcattc acgattatat
    47581 tgcctcccct accctcatta agtgtggcag cgcttacctg tccgccatcc aggataatca
    47641 gcttccctgt gtgaatctct acatcaccag cgtttccagt acctctggtc tgtactccca
    47701 aggtgctggc aacattcgta ttttggtcaa tgccaatcac ttccactgac tttgaagcat
    47761 tgacaagtat attgcctcca gtaccctgat tcaatgtggc agcgcttacc tgtccgccat
    47821 ccaggataat cagattccct gtgtgaatct ctacatcacc agcttttcca gtccctctgg
    47881 tctgtgcttc caagctgctg gcaacagtcc cattttggtc aatgccaatc acttcgactg
    47941 actccctcgc attcacgagt atattgcctc cactaccctg attagatgta gtagagctta
    48001 cctgtccgcc atccaggagt atcagattcc ctgtgtgaat ctctacatca ccagcttttc
    48061 cagtccctct ggtctgtgct tccaagctgc tggcaacagt cccattttga gcaatgccaa
    48121 tgacttcgac tgattccctc gcattcacga gtatattgcc tccacgaccc tgattcaatg
    48181 tggtagcgtt tacctgtccg ccatccagga gtatcagatt ccctgtatta atttctattg
    48241 tgccaccctc acca
//
