LOCUS       NZ_CP053549            25270 bp    DNA     circular CON 17-AUG-2024
DEFINITION  Paenarthrobacter sp. YJN-D chromosome, complete genome.
ACCESSION   NZ_CP053549
VERSION     NZ_CP053549.1
KEYWORDS    RefSeq.
SOURCE      Paenarthrobacter sp. YJN-D
  ORGANISM  Paenarthrobacter sp. YJN-D
            Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
            Micrococcaceae; Paenarthrobacter.
REFERENCE   1  (bases 1 to 4334173)
  AUTHORS   Zhang,M.
  TITLE     Comparative genomic analysis of iprodione-degrading
            Paenarthrobacters reveals the iprodione catabolic molecular
            mechanism in Paenarthrobacter sp. strain YJN-5
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4334173)
  AUTHORS   Zhang,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-MAY-2020) College of Life Sciences, Nanjing
            Agricultural University, Weigang NO.1, nanjing, jiangsu 210095,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.3 OR MAY-2019
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015040335.1-RS_2024_08_17
            Annotation Date                   :: 08/17/2024 05:55:21
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,216
            CDSs (total)                      :: 4,145
            Genes (coding)                    :: 4,122
            CDSs (with protein)               :: 4,122
            Genes (RNA)                       :: 71
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 23
            CDSs (without protein)            :: 23
            Pseudo Genes (ambiguous residues) :: 0 of 23
            Pseudo Genes (frameshifted)       :: 6 of 23
            Pseudo Genes (incomplete)         :: 18 of 23
            Pseudo Genes (internal stop)      :: 1 of 23
            Pseudo Genes (multiple problems)  :: 2 of 23
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:51:13
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1200931
            Orig. end                         :: 1226201
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP053549.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25270
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="6"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..25270
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25270
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:15270](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15270)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(196..210)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     gene            complement(254..703)
                     /locus_tag="HMI60_RS05680"
                     /old_locus_tag="HMI60_05695"
     CDS             complement(254..703)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018778925.1"
                     /locus_tag="HMI60_RS05680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_05695"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_018778925.1"
                     /transl_table=11
                     /translation="MTPQELANLAHLRRARDFIDREYARPLDVPTMAAGALMSPAHFSR
                     QFKAAYGESPYNYLMTRRIERAMALLRAGTSVTDACMEVGCTSLGSFSSRFTEIVGITP
                     SEYRSREHHAVKAMPNCIAKQHTRPDRKGNTNLSRIEEAQAPKLQ"
     gene            730..1347
                     /locus_tag="HMI60_RS05685"
                     /old_locus_tag="HMI60_05700"
     CDS             730..1347
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014920477.1"
                     /locus_tag="HMI60_RS05685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_05700"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_055977433.1"
                     /transl_table=11
                     /translation="MESVVWSKPENQRKGTPLLVMLHGYGTSEQRMVNLFDQLPTEFTC
                     AALRGPKVIGDDYGWFLLDYFLTNDFADVIASTNAVFDWINSVKDNHSSVSLLGYSQGM
                     AMASTLLRLRPASFKATVGLSGFVLDNDLLALSESFDTPPPFFWGRDKADPVINEDAIA
                     HTEEWLNANTALTARTYPGMGHRIDPVELVDVSAFLKYYVLG"
     misc_feature    complement(1392..1407)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.24"
                     /tool="antismash"
     gene            1552..2553
                     /locus_tag="HMI60_RS05690"
                     /old_locus_tag="HMI60_05705"
     CDS             1552..2553
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018778923.1"
                     /locus_tag="HMI60_RS05690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_05705"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_227453660.1"
                     /transl_table=11
                     /translation="MTIQDVAVLSGLSICTVSRALRKLPNVSEKAQSRVAEAASKLGYK
                     ASAAASRLAGGNTGAVAIVAPTATSWFFSQAVEAAEEVLGDSGYDTVLISLRNKATVRK
                     QFFADLENLAQRVDGLLLLNIDLEPGELEALEACGLAVASVGMRNVPWDNVGIDDEHAA
                     WQATQHLLGLGHWNLAVLSSNEHSVVTETPRFRGFRRALDEHHLTVHPDLVVASGPGID
                     DGRRAMTELITRGAKPTAVFAHCDEAAFGALTALREYGLSVPKNVSVIGIDDHPMSWFL
                     GLSTVAQPVADQGAFAANLLCERLLNNESPHQPSNHLLDTKLIERKTTRHKR"
     gene            2562..3293
                     /locus_tag="HMI60_RS05695"
                     /old_locus_tag="HMI60_05710"
     CDS             2562..3293
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017197119.1"
                     /locus_tag="HMI60_RS05695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_05710"
                     /product="HAD family phosphatase"
                     /protein_id="WP_193590717.1"
                     /sec_met_domain="HAD_2 (E-value: 9.9e-16, bitscore: 56.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHMTDLRNAWTGASALLFDLDGVLTPTAVVHEQAWQELFDGYLAR
                     IGHREGYQESDYFDHIDGKPRFDGVRDFLTSRGITLPEGPTDDSPTNQTVQGLGNRKNA
                     IFNEIVDTRGVEPYEGSVKFINAALERGLKIAVVSSSRNAPAVLKAAGLDHNFEVVVDG
                     QVAAAVGLPGKPDPATYVYGAGLLGVPVEECIVVEDAVSGVQAGAGAPFYAVIGVDRGA
                     GRQTLLDAGATLVVDDLNELL"
     gene            3324..5681
                     /locus_tag="HMI60_RS05700"
                     /old_locus_tag="HMI60_05715"
     CDS             3324..5681
                     /GO_function="GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017197120.1"
                     /locus_tag="HMI60_RS05700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_05715"
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="WP_018778921.1"
                     /transl_table=11
                     /translation="MALISSDRLRFPCEPWKLVENIHVPGDEGTLETLFALGNGHLGIR
                     GSHSTAGDSELPGTFINGFHEIWDIKHAENAYGFARTGQRIVYVPDANNFTVSIDGEAL
                     SLAESTVLDYHRSVDFSTGVYEERIVWSCRSGATVTTVERRAVGFDSRGCLGLELSLSA
                     DRDVSADITSGVVNRQDQPVEDHSVHDPRRSGRHAGRVLLPLHLQGADGSLRLAWETSE
                     SRQRVAMAVDHWISAEGQPFETLVAEDESSVRYVLAIHDGDTFRLEKTVSYVVAGSAGD
                     AEDRGESLAAEAEANLVPFSEILAQSKAHYDEYWTTADVSIGGQAEMQQAVRWGLFQLA
                     QATARAGVAGIPAKGVSGSGYEGHYFWDQEIYLLPYLTYTNPCGARKVLESRHAMLPDA
                     RVRAKELSVDGALFPWRTINGLEASAYYAAGTAQFHIAAAIAFAANRYQWASGDDTFSA
                     ELGADLLIETARMWASLGFFGKDGMFHIHGVTGPDEYTAVVNDNLYTNVMARFNLRAAA
                     ALEHEGIAETERMVWRQAAERMSLPYDPHLQVFSQDNDFMTLEPWDWNTPKSKYPLLLN
                     FHPLVIYRHQVLKQADTVLAMFLQWQDFTAEEKQRAFDFYDPITTGDSTLSACVQGIMA
                     AEVGYGDVALQHFTEALFIDLDNSHGNTIDGVHIASTGGIWSSLVCGFAGMRDQGEVLR
                     FDPRLPVEWDGLSFRLKVQGRLLAVELEQGSIALTLVPGPDYSEEPLQVKVRDYDVTVG
                     TATVQVPLEDVPVPPPSIFPSVFPTAGLPIIR"
     gene            complement(5687..5878)
                     /locus_tag="HMI60_RS05705"
                     /old_locus_tag="HMI60_05720"
     CDS             complement(5687..5878)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018778920.1"
                     /locus_tag="HMI60_RS05705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_05720"
                     /product="hypothetical protein"
                     /protein_id="WP_018778920.1"
                     /transl_table=11
                     /translation="MAGHFELFDESGGDCRVRLVDADGTELALSICFQDRATAAKAIYS
                     LREIAASGLIEDHTSRAS"
     gene            complement(5879..6259)
                     /locus_tag="HMI60_RS05710"
                     /old_locus_tag="HMI60_05725"
     CDS             complement(5879..6259)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018778919.1"
                     /locus_tag="HMI60_RS05710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_05725"
                     /product="hypothetical protein"
                     /protein_id="WP_018778919.1"
                     /transl_table=11
                     /translation="MAPNSFKANILLTHGVAASAASVARRRAAVTQGSHGAANKPDALL
                     GAIAVRQLFHRWPLVPSRELERIRHVLLHCDQLGSPDTHHLSEPAQALLELINSELDRR
                     RTAEGRPQAPAAEAPATRKGAA"
     gene            6381..7136
                     /locus_tag="HMI60_RS05715"
                     /old_locus_tag="HMI60_05730"
     CDS             6381..7136
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /GO_function="GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA]"
                     /GO_process="GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014920482.1"
                     /locus_tag="HMI60_RS05715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_05730"
                     /product="bifunctional 2-polyprenyl-6-hydroxyphenol
                     methylase/3-demethylubiquinol 3-O-methyltransferase UbiG"
                     /protein_id="WP_018778918.1"
                     /transl_table=11
                     /translation="MTDQQELWNEETAQQYDTPGEGMFSPDVLGPTVQVLSELAGDGAA
                     VEFAIGTGRVAVPLVEAGVPVSGIELSHAMIRRLRSKADAATIPVVQGDMAEAQVQGEF
                     TLAYLVFNTIANLLTQEEQVRCFQNAARHLAPGGRFVIELWVPQLRSLPPGHGGTVEVS
                     QPGYLLVDSYDVLRQHVISHHVRFGPGLSDGRDARISRTPHRYIWPSELDLMARIAGFQ
                     LESRWADWDRSDFTAESRSHVSVYRLVHR"
     gene            7408..8526
                     /locus_tag="HMI60_RS05720"
                     /old_locus_tag="HMI60_05735"
     CDS             7408..8526
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011773077.1"
                     /locus_tag="HMI60_RS05720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_05735"
                     /product="hypothetical protein"
                     /protein_id="WP_193590718.1"
                     /transl_table=11
                     /translation="MPSYLKPTELHEALTIRDLSNPDQGPHAMQQLLHDTVRGLRGQWN
                     VSERIIRHSPLVSVSDNYDRLGFSAADVTRDQKYSRYISPTVMLRSHTSASIPSLLRSL
                     DPDGSLDELWAIPGVVYRRDAIDRTHVGTPHQVDLWRVSSKETLTASHLGEMVGSLVNA
                     VLPGADWRTVPATHPYTHNGLQLDVRMNGEWLELAECGLMAPQLFLDAGLNPGHWSGLA
                     LGMGLDRALMLRKGVPDIRLLSSDDPRIQQQMLDLSPWRPVSHMPSISRDISIVVAADM
                     DGEVLGDRVRTALGYRAEDLESVELMALTAYHELPARARDRLQILDGQANALIRLVLRP
                     LGRTMTDPEANQVRDDVYLALHEGPVKELIAG"
     gene            complement(8552..9373)
                     /locus_tag="HMI60_RS05725"
                     /old_locus_tag="HMI60_05740"
     CDS             complement(8552..9373)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018778916.1"
                     /locus_tag="HMI60_RS05725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_05740"
                     /product="tryptophan-rich sensory protein"
                     /protein_id="WP_193590719.1"
                     /transl_table=11
                     /translation="MATGSPDPTRQIAVTASLVVCIVGSMIGVGVFGGTPIAQAAGGAL
                     AADSTLLAPATPAFSIWSVVYTGLVAYTVWQWLPSQRSSIRQRALGWVVAASMILNAAW
                     ILSVQAGWLFVSVLVILALLATLVLAFLRYSRTRASSWVEAVVVDGTLSLYLGWTSVAV
                     CANIAAALKAAGFSGFGLQPEVWSVAVLVVVAVIGVALAFKGHGRLALAAAIAWGLVWI
                     TVGRSSDAPESFPTAVAAAVAAALVLGAAIAMRTRVALAGAGTRSSSSPLQ"
     gene            9485..10006
                     /locus_tag="HMI60_RS05730"
                     /old_locus_tag="HMI60_05745"
     CDS             9485..10006
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018778915.1"
                     /locus_tag="HMI60_RS05730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_05745"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_018778915.1"
                     /transl_table=11
                     /translation="MDSEGHAKGYWYGKDPGQKAIAIDVLNALRDYRASEQAMRRRTRS
                     SMGMGEKDLLALRYLFEAEADGKVMKPKDLGDKLGITSASMTTLIDRLVESGHIRREPH
                     PTDRRALILKATPGSDQEVRHTLGGMHRRMLDAASALSPDESRVVVDFLQHMREALDTI
                     DEEPGEPSGS"
     gene            complement(10001..11200)
                     /locus_tag="HMI60_RS05735"
                     /old_locus_tag="HMI60_05750"
     CDS             complement(10001..11200)
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl_fung"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018778914.1"
                     /locus_tag="HMI60_RS05735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_05750"
                     /product="prenyltransferase"
                     /protein_id="WP_193590720.1"
                     /sec_met_domain="Lycopene_cycl_fung (E-value: 2.2e-11,
                     bitscore: 42.0, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="ubiA (E-value: 2.3e-15, bitscore: 54.5,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYLWLALAFIAAAAVAGVIFARRGARQGEASRHWKAVGLAFAAL
                     AVLTAVFDSVMIGMELFHYDASHILGLKAGLAPIEDFAYPLAGVVVLPGLWMWLTRRRS
                     AGAKSDLTGLVPQAILASRPVSWINTAYPFAAAMLLTTREIDWVLIVGTFYFLIPYNLA
                     MYGINDVFDYESDLKNPRKGGIEGALLRPQLHRPMLWLAAVTNVPFLLVLAFAGGPAVW
                     LSLAVSAFAVVAYSVAGLRFKERPVLDSLTSSTHFVSPAVVGLALAGAEVTPGLLLLLT
                     AFFLWGMAAHAFGAVQDIEPDRQAGIGSIATVIGARRTVRLAVVLWFVAGLSMLATPWP
                     GPLAAIIAVPYIVNCAPYWNVTDTTAARTNVAWRRFIWLNYGSGFLVTLIFILQWSLTS
                     "
     gene            complement(11197..11547)
                     /locus_tag="HMI60_RS05740"
                     /old_locus_tag="HMI60_05755"
     CDS             complement(11197..11547)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl_fung"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018778913.1"
                     /locus_tag="HMI60_RS05740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_05755"
                     /product="lycopene cyclase domain-containing protein"
                     /protein_id="WP_018778913.1"
                     /sec_met_domain="Lycopene_cycl_fung (E-value: 2.5e-15,
                     bitscore: 54.6, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGVLYLASLLLGITCMLLLDHRFRLFFWHDAKAAAIVTAVGVLFF
                     LGWDAAGIGLGIFLRGEGTIATGLLIAPELPIEEPVFLLFLTLCTMVLYTGARRLLERS
                     PARQAERERENA"
     gene            complement(11547..13199)
                     /gene="crtI"
                     /locus_tag="HMI60_RS05745"
                     /old_locus_tag="HMI60_05760"
     CDS             complement(11547..13199)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011773083.1"
                     /locus_tag="HMI60_RS05745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_05760"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_110505965.1"
                     /sec_met_domain="DAO (E-value: 4.3e-11, bitscore: 40.9,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTVVIGGGIAGLATAALLAHEGHEVQLLEQRDRVGGRAGSLER
                     DGFRFDTGPSWYLMPGVFDHFFELLGTSTAEQLDLRTLSPAYRVFSEPNLDGVRPDTLT
                     VPLGSEQVLETFEDVEPGSARKLATYLASARHTTDMAERFFLYNPFTRLQGLLQPEVLR
                     SLPKLAQLLLTPLDKYVARRFQHPVLRQVLGYPAVFLGTSPSDAPAMYHLMSALDLGDG
                     VQYPMGGFWELVGRLEDLAVQAGVRIHTGAEALKITTRAVSRTKKVGRFDGVKLPAALT
                     GRDSREVTGVTWRDTSGNEHYSVADLVVSGADLHHTETQLLGVRDRSYPGSWWQRRTSG
                     PGAVLVMLGVKGKLPELPHHSLFFTRDWEANFASIFGENPAIPDPASIYVCKPSATDPA
                     VAPTDHENLFVLVPIPADPALGAGGPDGAGDVLIERTADAAIDQIAQWAGIPDLRDRIV
                     VRQTTGPADFARDYNSWRGGMLGPAHTLGQSAMFRPQNASKRVQGLYYAGATTAPGVGV
                     PMCLISAELVLKRIRGDHSTGPVTVRPVASRIG"
     gene            complement(13196..14101)
                     /locus_tag="HMI60_RS05750"
                     /old_locus_tag="HMI60_05765"
     CDS             complement(13196..14101)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011773084.1"
                     /locus_tag="HMI60_RS05750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_05765"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_193590721.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.9e-29, bitscore:
                     99.3, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 8.4e-31,
                     bitscore: 105.2, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLASDTSFTHFTRTAERAANQVIAAYSTSFGLACKLLGRRHRQH
                     VRNIYALVRVADELVDGVTAEAGLSYQEQCDALAHFIDETHRAVKLGYSSDLIIHAFAQ
                     TARAARIDESLIDPFFDSMRTDLGERTGTPETPLRFDADAHQGYVHGSAEVVGLMCLRV
                     FMRDENIDDGDAAALQHGASRLGAAFQNINFLRDLADDTTRLGRNYLGTSEHLEDHDRV
                     EWVRTIRAQLADADAVIPLLPRDARAAVRSALSLFTALTDRIEQTTVDELYRSRVRVPD
                     AVKAGLAARAVTSTWMELHR"
     gene            complement(14098..15270)
                     /locus_tag="HMI60_RS05755"
                     /old_locus_tag="HMI60_05770"
     CDS             complement(14098..15270)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011773085.1"
                     /locus_tag="HMI60_RS05755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_05770"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_079582359.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.9e-40, bitscore:
                     135.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVTSGALRSRTDLCTAIENELSGLIGKRAAAATTYGPHFTRLWE
                     LAGHNVLGGKFVRPLLLMETYDALRGRGTDGTGQPRTNQPQASPPDTGHRETAISIAAA
                     IELLHYSFLLHDDVIDGDLVRRGHPNLIGSLLAEAKSLSETQSLPRTNSGEGAREGSDL
                     HWAQTGGILMGDMLLAATHQAFARADLPHALRLRLLDLLEHTINETVAGEQLDVGLGDG
                     IIDPHLETILVMCGYKTATYTFELPLRAAAALAGADFAVENALATAGRHLGLAFQLQDD
                     LLSTFGDPRRHGKDPFSDLREGKETAIIAHARTTAAWPDIEPFFGRPELNGSECEYVRR
                     HLADCGAETFVNGLIEEQMRAFNELLTSTIPQGVCNVLLDLAGQLEGRQS"
     gene            complement(15267..15821)
                     /gene="idi"
                     /locus_tag="HMI60_RS05760"
                     /old_locus_tag="HMI60_05775"
     CDS             complement(15267..15821)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="idi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017200776.1"
                     /locus_tag="HMI60_RS05760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_05775"
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_018778909.1"
                     /transl_table=11
                     /translation="MNATEMVVLLDDAGTPIGEAPKAGVHTQETPLHLAFSCYLLNDDG
                     EVLLTRRSPEKKTWPGVWTNSFCGHPAPGEDPLDAVARRAQFELGVDANQVEMALPHFR
                     YRAVDPTGIVENEICPVYVARIAGDLKPNPSEVADWAWMSPALLANSLERTPSAFSPWL
                     GLQFPQLLEARVLPLGTGAKA"
     gene            15927..16514
                     /locus_tag="HMI60_RS05765"
                     /old_locus_tag="HMI60_05780"
     CDS             15927..16514
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018778908.1"
                     /locus_tag="HMI60_RS05765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_05780"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_193590722.1"
                     /transl_table=11
                     /translation="MSSLEEMPDEAGFPVSSGLYHLDANDPHQQLIDRSRFSEADIEQI
                     SELMAALGRLRDAEQRLAEASLRYMKLNQSDMRALHYLIVCANHGVIATPGAIASHLNI
                     STASTTKLLDRLERAGHVTRQAHPSDRRALAIAITPETHEAAMRTVGKQQAKRFLAAAR
                     LTPDERVAVMRFLDDMAREIEVADEPWAAAPR"
     misc_feature    complement(16541..16556)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.36"
                     /tool="antismash"
     gene            16648..17754
                     /locus_tag="HMI60_RS05770"
                     /old_locus_tag="HMI60_05785"
     CDS             16648..17754
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018778907.1"
                     /locus_tag="HMI60_RS05770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_05785"
                     /product="EAL domain-containing protein"
                     /protein_id="WP_193590723.1"
                     /transl_table=11
                     /translation="MAQEAGSLSPGDDADSSNHDGAGDTPFADEVTMRAQVLDIIESIL
                     EDAEPRSEGARNKLRELLDARPDDPEGALLKHLLLTRKTSQPASNVPVHLEHASLHLES
                     SDASRTVLVPVSHDVRAGIQSILADKLLLTAFQPIHSLPKGDPIGVEALTRFIGEDGAG
                     ADVWFSEAAAAGLGTELEIAALHCALMAAHDVPENMFVTLNLTPATSHDPRVRNLLAAA
                     ALAPERIIVELTGSLESMAAQPDGEGLEQLRALGLRVAISASGAALVSLDRIEQLRPDI
                     IKLDRHLIEGIAGNDGQKLRAKAIVELAREIGADVHAQGIETAEELHEVTALKVTAAQG
                     YLLGRPSVHPLDWSAWSVRAQTEPQPAS"
     gene            complement(17849..18730)
                     /locus_tag="HMI60_RS05775"
                     /old_locus_tag="HMI60_05790"
     CDS             complement(17849..18730)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018778906.1"
                     /locus_tag="HMI60_RS05775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_05790"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_193590724.1"
                     /transl_table=11
                     /translation="MDAPDAGGLAQDGSGSFRAGLHPWSRYVALGDSFTEGLGDPEPRS
                     PGGLRGWADRVAEELSTDHHDFAYANLAISGKLLHQILEEQVGPALDLKPDLITLNAGG
                     NDLLFHRSDPDKLALELDRGVETLASTGATIVLFTGPDWGATPVLGRTRGKVAVFNENI
                     RVVAARHDAVIADLWALRQLTDPRMWDPDRLHFSPLGQHIIAIMVLESLNVPHSLEPLA
                     PRPLPERRWREARADDIVWAREHLFPWVVRRLTQRNADGGRHPKRPQPGPVFGAAMPPG
                     SYVGNDPRRITD"
     misc_feature    18716..18730
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            18844..19794
                     /locus_tag="HMI60_RS05780"
                     /old_locus_tag="HMI60_05795"
     CDS             18844..19794
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018778905.1"
                     /locus_tag="HMI60_RS05780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_05795"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_193590725.1"
                     /transl_table=11
                     /translation="MAASRKRSDSSSTLLTVVIAFAANALVAAAKSVAAALTGSASMTA
                     EAAHSWADTGNQVFLFLAERRSQRPRDTGHPMGYGREAYVWSMFAAFGLFTAGAVVSIM
                     HGIQQIIEPEPASDFLIAYVVLAVAFVLEGFSFVQAFRQTRKAARKLERRTLEQVLVSS
                     DPTLRAVFSEDAAALVGLVIAFTGVFLHQVTGSPLPDAVGSIVVGVLLAVVAVVLIDRN
                     RRFLVGQGVTPDIERSMGRQLLEHRDIARLTYLHLEFVGPRKLYLVAAVDLQGDHPEHE
                     VAVVLRRIERELEDHETVEEAVLTLATPDESSLQL"
     gene            complement(19805..20641)
                     /locus_tag="HMI60_RS05785"
                     /old_locus_tag="HMI60_05800"
     CDS             complement(19805..20641)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018778904.1"
                     /locus_tag="HMI60_RS05785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_05800"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_064723575.1"
                     /transl_table=11
                     /translation="MKDERRKELGLYLRTRRNQALRSDYGLPPVGRSRERGLRREEIAF
                     LSGVSVTWYTWLEQGRDISPSRQVLESIARALHLSDTGLGYVLSLGGYASTIPKGPVAA
                     DAPAHVQRLLDALDPNPSYALSPDWGVAGWNRAYEALYPNIGTFDAADRNLLWLVFTDP
                     YVRDLLPDWDVTSKRFLAEFRAETGQRLGDPDVAYQVERLKEASPEFQESWDRYDILGF
                     ESRERLFHHPAVGVLQLEHHQVSPSDRPDLHIVVYTPAPGSDAGEQMERLLETGRS"
     misc_feature    20661..20677
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 19.7"
                     /tool="antismash"
     gene            20728..22590
                     /gene="ilvD"
                     /locus_tag="HMI60_RS05790"
                     /old_locus_tag="HMI60_05805"
     CDS             20728..22590
                     /EC_number="4.2.1.9"
                     /GO_function="GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="ilvD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011773119.1"
                     /locus_tag="HMI60_RS05790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_05805"
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="WP_079582355.1"
                     /transl_table=11
                     /translation="MPALRSRTVTHGRNMAGARALLRASGVANTDIGKPIIAVANSFTE
                     FVPGHTHLAPVGRIVSDAILAAGAVPREFNTIAVDDGIAMGHSGMLYSLPSRDLIADSV
                     EYMVNAHCADALVCISNCDKITPGMLMAALRLNIPVVFVSGGPMEAGRVTLTDGSVRSL
                     DLVNAIADAVDESISDEDINLIEENACPTCGSCSGMFTANSMNCLAEAIGLALPGNGSV
                     LATHTARKALYEKAGATVVELVKRYYDGDDDSVLPRSIATAEAFDNAMALDISMGGSTN
                     TILHLLAAAQEAGVEYGLAEMDAKSRQVPCLAKVAPNVAGNKTYYMEDVHRAGGIPALL
                     GELNRGGLLHKNVHSVHSADLEGWLDDWDIRGGKATEEAQALWHAAPGGVRSSTAFSQS
                     NEWTSLDTDAEGGCIRSVEHAFSKDGGLAVLRGNVAVDGAVVKTAGVDESIWTFEGPAV
                     VCESQDEAVEMILNKTIKEGDVVVIRYEGPRGGPGMQEMLYPTSFLKGRGLGKKCALIT
                     DGRFSGGTSGLSIGHISPEAASGGAIALVENGDIISIDITQRSLQLQVSDEILAERREK
                     LEVNGGYKPKNRDRQVSPALRAYAAMALSADKGAVRDVSLVENL"
     gene            22756..24414
                     /locus_tag="HMI60_RS05795"
                     /old_locus_tag="HMI60_05810"
     CDS             22756..24414
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018778902.1"
                     /locus_tag="HMI60_RS05795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_05810"
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="WP_193590726.1"
                     /transl_table=11
                     /translation="MGIGGQVAEGQAESSSDSAVDCLEDGIDALDGVRASILAQASMFD
                     FGEASAFAGRVEDIARTVEYLQLVAARAVERTRKEAGTAAVLDDGYRNAGDFLRARLRI
                     TAKEARRRLALADAVLPGVGIAGEPVPPQREQLASAVADALVSGGSATLISTALDRVHL
                     LTDQDTITRMEKDLTSTAIQSDTDFVSTTARRWMDFIDQDGAEPTEEVLRQLQGAFIRK
                     PRFGLNHLEIFATAEQFETLTTVMNAATNPRLVEGGVRNTGSSGGPGGRNGPSRTAVHT
                     TQRGADTRGRSSAAQVRTPEGRVAATVRMEPANGRNPIPEPGRRSRAQKLLDGLVGGCA
                     LALRTGQLPANGGLKPQVMVTIDYRDLFDQLQSHAANQQTGNPVGTGETDPGTRAAGNG
                     TTGTGGLRPRLSSAVSTFQGPIHPNVIRKIACDADILPVLLGTEGQVLGIGRTSRIFPP
                     HIRKALQARDQGCAFPDCTMPAPWCEAHHITYWSQGGPTNTDNGVLLCSHHHHVIHKEQ
                     WMIASRNGIPWFIPPAHVDPSQAARRNHHHAPLRT"
ORIGIN
        1 cggcatgacg cccttggtga ggagttcctg gatggcgtca ccgtcagcct gggagcggcc
       61 ggcgtgcggc ggggagagga ccagttcgag gtcgggctgg gcgtcgctgc ccaaggtcac
      121 ccagcgctgg ccatccgagc cgacgtcgtt gcggacctcc aggccgagcg cgtcgcggta
      181 gaaggcgagc gactcatcga catcgttgac agtgacgtgt gcgtacttca atgaaatgtt
      241 catgaaccac acgctattgc agcttgggag cctgcgcttc ttcaatcctg ctcaggttgg
      301 tgttgccctt cctgtcggga cgagtgtgct gtttggcgat gcagttcggc atggctttca
      361 cggcgtggtg ctcccgggag cggtactcgc tgggcgtgat ccctacgatt tcagtgaagc
      421 ggctgctgaa ggagcccagg gaggtacagc cgacttccat gcaggcatcc gtaacgctgg
      481 tcccggcacg aaggagggcc atggcccgtt ctatccgccg ggtcatcagg tagttgtagg
      541 gcgattcgcc gtatgcggcc ttgaactggc gggagaagtg cgccggtgac attagggcgc
      601 cggctgccat ggtgggcacg tccaaaggac gcgcgtactc gcggtctatg aagtcgcggg
      661 cgcgccgcag atgggccagg ttggccaatt cctgcggtgt catggcgtca gtctactagg
      721 ctcatgccca tggaatcagt ggtctggtca aagcccgaaa accagcgcaa gggcactcct
      781 ttgctggtga tgctgcatgg ttacggcacc agcgagcagc gcatggtcaa cctttttgac
      841 caactgccca cggagttcac ctgtgctgcg ttgcgggggc ccaaggttat cggcgacgat
      901 tacgggtggt tcctgctgga ctacttcctg accaacgact tcgcggatgt gattgcctcc
      961 acaaatgcgg tgttcgactg gatcaactcc gtgaaagaca accacagcag cgtgagtttg
     1021 ctcggctact cacagggcat ggccatggcc agcacgcttc tgcggttgcg gcccgcgtcg
     1081 ttcaaagcca ccgtcggctt gtccggattt gtcctggaca acgacctgct tgccctgagt
     1141 gaatcattcg acaccccgcc gccgttcttt tgggggaggg acaaagcgga ccccgtgatc
     1201 aacgaggacg cgatcgccca cacggaggag tggttgaacg ccaacacggc gttgacggca
     1261 cgtacttatc ccgggatggg gcaccggata gaccctgtcg aattggtgga tgtcagtgct
     1321 ttcctgaagt actacgtgct gggctagggc tggattagaa ggcattccca ccccggaatc
     1381 aaacctgttg gtgagattcg cgtcacaatt tcgcattcaa gcacactcta ttgaatgaca
     1441 aaattgtaag cgcttacact tttggctggt gacccggtcc gggacacacg ccaaggcgtc
     1501 aggcgagcat ggaaagggtt gaggccgtgt tgcatggtta ggactcacag ggtgacaatc
     1561 caggacgtag ccgtcctttc cgggttgtcg atttgcacgg tatcgcgggc actcaggaag
     1621 ctccccaacg tttctgaaaa ggcccagtcg cgggtggctg aagctgccag caagctcggc
     1681 tataaagcct cggccgccgc ctccaggttg gctggcggaa acacaggggc ggtggcgatc
     1741 gtcgccccca ccgccacatc gtggttcttc tcccaggccg tggaagccgc agaggaggtt
     1801 ctgggcgaca gtggctacga cacggtcctg atcagccttc gcaacaaggc cactgtccgg
     1861 aagcagttct tcgcggacct tgaaaacctc gcgcagaggg tcgacggact gctgttgctc
     1921 aatattgacc tcgagcccgg agaactggaa gcgttggaag cctgcggact ggcagtggcc
     1981 agcgtgggca tgcgaaatgt tccgtgggac aatgtaggta tcgatgacga acacgctgcc
     2041 tggcaggcaa cccaacacct gctggggctg ggccattgga acttggccgt tctctcgagc
     2101 aatgaacact ccgttgtgac tgagactcct cggttccgtg gcttccggcg tgcgctggat
     2161 gaacaccacc tcaccgttca cccggacctt gtggtggctt cagggccagg tatcgacgac
     2221 gggcggcggg ccatgactga gctcatcacc cgcggcgcga agcccacggc agtgttcgcc
     2281 cactgtgacg aggccgcgtt cggtgcattg accgcgctcc gggaatacgg cttgtccgtg
     2341 ccgaaaaacg tgtccgtgat cggaatagat gaccacccga tgagctggtt cctgggtctc
     2401 agcaccgtgg cgcagccggt agctgaccag ggcgccttcg ctgcgaacct gctgtgcgaa
     2461 cgactcctga ataacgaatc cccccaccaa ccctccaacc acttgctcga taccaagctc
     2521 atcgaacgca aaaccacgcg ccacaagcgc tgaacggaac tatgcacatg actgaccttc
     2581 gtaatgcctg gaccggcgcc tcggcgctcc tgttcgatct cgacggcgtg ctgacgccca
     2641 ctgccgtggt gcacgagcag gcatggcagg aactgttcga cggttacctg gcccggatcg
     2701 ggcaccggga gggttaccag gagagcgatt acttcgacca catcgatggc aagccgcgct
     2761 ttgacggcgt ccgggacttc ctgacctccc ggggcatcac gctcccggaa ggcccaacgg
     2821 acgactcacc cacgaaccag accgtccagg ggctcggcaa ccgcaagaac gccatcttca
     2881 acgaaatcgt ggacactcgg ggagtggagc cctacgaagg ttccgtcaaa ttcatcaatg
     2941 cggccttgga acggggactc aagatcgcag tcgtctcctc gtcaaggaac gctcctgccg
     3001 tgctgaaggc agcgggactc gaccacaact tcgaggtagt cgtcgacggc caggtggccg
     3061 ccgccgtcgg acttcccggc aagccggacc cggccaccta cgtgtatgga gcaggcctgc
     3121 tgggcgtacc cgtggaggaa tgcatcgtgg tggaagacgc cgtgtccggg gtgcaggccg
     3181 gcgcgggagc tcccttctac gccgtgatcg gcgtggaccg tggtgcgggc cgccagacct
     3241 tgctcgatgc cggcgccacg ctggtggtcg acgacctcaa cgaacttctc tgaccctact
     3301 ttttcgaagg acttcaacag cccatggcac tcatcagctc cgatcggctg cgtttcccct
     3361 gcgagccctg gaagcttgtg gaaaacatcc acgtacccgg tgacgaggga acgttggaaa
     3421 cgctgttcgc gctaggcaac ggccacctcg gcatccgtgg atcccattcc acggcgggag
     3481 acagcgagct tcccggcacg ttcatcaacg gtttccatga gatctgggac atcaagcatg
     3541 ccgaaaacgc ctatggattc gcacggacgg gccaacggat cgtgtacgta ccggatgcca
     3601 acaacttcac ggtttccatt gatggcgaag ccctgagcct tgccgagtcc acggtgttgg
     3661 actatcaccg cagcgtcgac ttctccacag gcgtttacga ggaacgcatc gtgtggtcct
     3721 gccggtccgg cgcgaccgtc accacagtgg agcgccgcgc ggtcggcttc gattcccgcg
     3781 gatgcctcgg ccttgaactg tcgttgtcag cggaccgcga cgtgtccgcg gacatcacct
     3841 ccggcgtcgt gaaccgccag gaccagcctg tggaggacca ctcggtccat gacccgcggc
     3901 gttcggggcg gcacgccggg cgggtactgc tgccacttca cctccaaggc gccgatggtt
     3961 cgctccgcct tgcctgggaa acgtcggagt cgcgccagcg cgtggcgatg gccgtcgacc
     4021 actggatttc ggccgaaggc cagccgttcg aaacgctggt ggcggaggac gagtcctccg
     4081 tccgttacgt tctggcaatc cacgacggcg acactttccg tttggagaag acggtcagtt
     4141 acgtcgtggc cgggtcagcc ggggatgccg aggaccgtgg cgagagcctg gccgctgagg
     4201 cggaggccaa cctggtgccg ttctccgaga tcctggccca gagcaaagcg cattacgacg
     4261 agtactggac cactgctgat gtatcgatcg gcggccaggc cgagatgcag caggcagtgc
     4321 gctggggtct gttccaactc gcgcaagcca ctgcccgtgc cggtgtggcc ggcattcccg
     4381 cgaagggggt cagcggctcc ggctacgagg gccactactt ctgggaccag gagatctacc
     4441 tcctgcctta cctgacctac accaacccct gcggcgcccg gaaggtgctc gaatcacggc
     4501 acgcgatgct gccggatgcg agggtacggg ccaaggaact cagcgtggac ggtgcgttgt
     4561 tcccgtggcg caccatcaac ggcctggaag cgagtgccta ctatgcggcg ggaactgccc
     4621 agttccacat cgccgccgcc attgcgttcg ctgccaaccg ctaccagtgg gccagcggcg
     4681 atgacacgtt cagcgcagag ctgggtgccg acctgctgat cgagacggcc cgcatgtggg
     4741 cctcgctggg gttcttcggc aaggacggaa tgttccacat ccacggcgtc accgggccgg
     4801 acgagtacac ggctgtggtg aacgacaacc tgtacaccaa cgtcatggca cgctttaacc
     4861 tccgggcagc ggccgcgctg gaacacgagg gcatcgccga aaccgagcgc atggtgtgga
     4921 ggcaggccgc tgaacggatg tccctcccgt acgaccccca tctccaggtc ttcagccagg
     4981 acaacgactt catgaccctg gaaccctggg actggaatac gcccaagtcc aagtacccgt
     5041 tgctgctgaa cttccacccg ctggtgattt accgccacca ggtcctcaag caggctgaca
     5101 cggtgctggc catgttcctc cagtggcagg acttcaccgc tgaagagaag cagcgcgctt
     5161 tcgacttcta cgatcccatc acgaccggcg actccaccct gtccgcgtgc gtgcagggca
     5221 tcatggcggc cgaggtcggt tacggggacg tcgcgttgca gcacttcacc gaggccttgt
     5281 tcatagacct cgacaactcg cacggcaaca ccattgacgg cgtccacatt gcctccaccg
     5341 gcggcatctg gagctcctta gtctgtggtt tcgcgggaat gcgggaccag ggcgaggtgc
     5401 tgcgcttcga tccccggctg cctgttgaat gggacggctt gtccttccgg ctcaaggtgc
     5461 agggccgcct gctggccgtc gagctggaac aagggtccat tgcgttgacc ctcgtgcctg
     5521 gacccgacta cagcgaggag ccgttgcagg tgaaagtgcg ggactacgac gtcaccgttg
     5581 gtaccgccac cgtccaggtg ccgctggagg acgttcccgt cccgccgccg tcgatcttcc
     5641 ccagcgtttt cccgacggcg ggtcttccga tcatccggta acccgttcag gaagcccgcg
     5701 acgtgtggtc ttcaatcagg ccactcgccg cgatttcccg tagcgaataa atggctttgg
     5761 ctgccgtggc cctgtcctgg aaacagatgg agagcgcgag ttcagtcccg tcggcatcga
     5821 cgaggcggac ccggcaatca ccgcctgatt cgtcgaacag ttcaaagtgg ccggccattt
     5881 acgccgcccc cttcctggtg gcgggtgcct ctgctgcggg cgcctgcggg cggccttccg
     5941 cggttcgacg ccggtccaac tcgctgttga tcagttccaa cagcgcttgg gccggctcgg
     6001 acaggtggtg ggtgtccggg gaacccagct ggtcgcagtg aaggaggacg tggcggatcc
     6061 tctccagttc gcgggagggc accagcggcc agcggtgaaa aagctgcctt acggctatgg
     6121 cgcccagcag ggcgtcgggt ttgttggctg caccatggct tccttgagtg actgctgctc
     6181 ttcgtcgagc aacggaggcc gcggaagctg cgacaccatg ggtgagaaga atgttggctt
     6241 tgaaggaatt gggggccatg aggacctccc tgatgagagc gatgaaagcc gactgcgtga
     6301 ctctgaatcc agcttacaga atgtgagtta tgtcatgtca atcgttacgc gcggttgccg
     6361 ggacctgcaa tagtggcagg atgaccgacc agcaggagct ctggaacgaa gaaaccgcgc
     6421 agcagtacga cacccccggt gaaggcatgt tctcgcccga cgtgctgggt cccaccgttc
     6481 aggtgttgtc ggaactcgcc ggtgacggtg ccgccgtcga attcgcgatc ggtaccggca
     6541 gggtggcggt gccgctcgtc gaagccggcg tgcccgtgag tggcatagaa ctttcccacg
     6601 cgatgatccg gcggctgcgg tcgaaggcag acgcggccac catcccggtg gttcagggcg
     6661 acatggccga agcgcaggtg cagggcgagt tcacgttggc gtacctggtg ttcaacacca
     6721 tcgccaacct cctgacccag gaggagcagg tccgctgctt ccagaacgcg gccaggcatc
     6781 tggcgccagg cggtcgtttc gtcattgagc tgtgggtgcc gcagctgcgc tcactgccgc
     6841 ccggacacgg tggaacagtt gaagtgagcc agcctggtta cctcttggtg gacagctatg
     6901 acgttcttcg ccagcatgtc atctcccacc acgtgcgctt cggcccgggc ctgtccgacg
     6961 gcagggatgc gcgcatcagc cggacgccac accgctacat ctggcccagc gaactggacc
     7021 tcatggcgcg gatagccggg ttccagctcg aatccaggtg ggcggactgg gaccgcagcg
     7081 acttcacggc cgagtccagg agccacgtgt cggtgtaccg gctcgtgcac cgttagggtc
     7141 aacctggctc tgaccaagcc catcacgggt tgtccgggtg cgggcctgtc aagcggtctg
     7201 cagtaaggct tccgggcctt gccataggtc cggtgccctg tgcagtcgcc acggacccgg
     7261 gtatagtcgg cccatgcctt cattgcgtcg atttacttgc ccccgaccgg tctccggtcg
     7321 cgagggctgt ttggcgcgcg cctaggtcct ggcacggaga gggtcggggg aggaagcctc
     7381 cacccacacc gaatccaagg accagccatg ccttcatatc tcaaacccac agaactccat
     7441 gaagccctga ccatccggga cctctccaat ccggaccaag gcccgcacgc catgcagcaa
     7501 ctcctccatg acaccgtgcg cggcctgcgc gggcagtgga acgtgtcgga acggatcatc
     7561 cgccatagtc cgttggtcag cgtttccgac aattacgatc ggctcgggtt cagcgccgcg
     7621 gacgtcacgc gcgaccagaa gtactcccgc tacatcagcc ctaccgtcat gctgcggagt
     7681 catacctccg cgtccatccc gtcgttgctg cgttcgctgg atccggatgg gtccctcgac
     7741 gagctctggg caatccccgg cgtggtttat cgtcgggacg ccattgaccg gacccatgta
     7801 gggacgccgc accaagtgga tttgtggcgc gtctcttcca aggagacgct gacggcctcc
     7861 catctagggg aaatggttgg ctcgctggtg aacgctgtgc tgccgggcgc ggactggcgg
     7921 acggttccgg caacccatcc ctacacgcac aacggcctgc agctcgatgt gcgtatgaac
     7981 ggtgagtggc tggagcttgc ggagtgcggg ctgatggccc cgcagctgtt cctggatgcc
     8041 ggattgaacc ccggtcactg gtcgggactg gctctcggga tgggcttgga ccgggccctg
     8101 atgctccgca agggcgttcc cgacatcaga ttgctcagct cggacgatcc ccggattcaa
     8161 cagcagatgc tggacctctc accgtggaga ccggtgtccc acatgccgtc catcagcagg
     8221 gacatctcaa tcgtcgttgc cgcggatatg gatggcgaag tgctcggaga ccgggtgcgg
     8281 acggctctgg gttaccgggc ggaggacctg gaaagcgtcg aactgatggc cttgactgcg
     8341 taccacgagc ttcctgccag agcgcgtgac cgtttgcaga tcctcgacgg gcaggccaac
     8401 gcgctgatcc ggctcgtctt gcggcctctc ggccgcacga tgacggatcc ggaagccaac
     8461 caagtccggg acgatgtcta tctggcgttg cacgaaggcc cggtgaagga gctcatcgca
     8521 ggctgaagca acccgtgcca aggccgccgg gctattgcag cggggaggac gaactccggg
     8581 tacctgcccc ggccaaggcc acccgcgtcc tcatcgcgat cgcagcaccc aggaccagtg
     8641 cagctgcgac ggcggccgcg accgccgtcg gaaatgactc aggtgcgtcc gagctgcggc
     8701 caaccgtgat ccataccagg ccccacgcga tggccgcagc gagggcgaga cggccatggc
     8761 ctttgaaggc caacgcgacg ccaatgaccg ccaccaccac cagcacggca acggaccaca
     8821 cctcgggttg caggccgaat ccggagaatc cggcagcctt caaagcggca gcgatattgg
     8881 cgcacaccgc cacgctggtc cacccaagat agaggctcaa agttccgtcc accacaacgg
     8941 cctccaccca tgaggacgcg cgggtccggc tgtagcggag aaacgccagg acgagggtcg
     9001 caaggagtgc caggatcacc aggacgctga caaaaagcca tcccgcctgc actgacaaga
     9061 tccatgccgc attcaggatc atcgacgcgg caaccaccca gcccaacgcc cgctgccgga
     9121 tactggaacg ctgggacggc aaccactgcc acacggtgta ggcaaccagt ccggtgtaaa
     9181 ccacggacca gatggagaac gcgggcgtgg ccggcgccag gagggtggaa tcagcggcca
     9241 aggcaccgcc cgcggcctgg gcaatgggtg tgccgccaaa gactccgact ccgatcatcg
     9301 agccaacaat gcagacaacc agactcgccg ttacagcgat ctgtcgtgtg ggatcggggc
     9361 ttccggttgc catatgctgc gcctctttcc tgatgggatg tgcggtttca tgcattcggg
     9421 gtgtccgtga cttagtatca aattgctagt gaagcgagct ttatgcttat cgaaggaaca
     9481 tcggatggat tcggaaggcc acgcaaaggg ctattggtac gggaaagacc ccgggcagaa
     9541 ggccatcgcc atcgatgtcc tgaacgcgct gcgggactat cgagcctccg aacaagcgat
     9601 gcgccgcagg acccgctcgt ccatggggat gggcgagaaa gacttgctgg ccctgcggta
     9661 cctttttgag gcggaagccg acggcaaagt gatgaagccg aaggacctgg gcgacaagct
     9721 gggaataacg tcggcgtcca tgaccacctt gattgaccgt ctggtggagt caggccacat
     9781 ccgccgtgaa ccccatccca ccgatcgtcg cgcgctgatc ctgaaggcca ccccgggatc
     9841 ggaccaggaa gtccggcaca ccctgggcgg aatgcaccgc cggatgttgg acgcagcgtc
     9901 tgcgctgagc ccggacgagt cacgggtcgt ggtggatttc ctgcagcata tgcgggaggc
     9961 cttggacacc atcgacgaag agcccggaga accgtccggg tcatgacgtc aggctccact
    10021 gcaggatgaa gatcagggtc accaggaatc ctgaaccgta gttgagccag ataaaccgcc
    10081 gccatgccac attggtgcgt gccgccgtcg tatccgtgac gttccagtac ggtgcgcaat
    10141 taacgatgta cgggacggcg atgatcgccg ccagcggccc gggccacggc gtggccagca
    10201 tcgagagtcc cgcaacaaac cacaggacga cggcgagccg caccgtccgg cgggcaccga
    10261 tgaccgttgc gatggagccg atgccggcct gccggtcggg ctcgatgtcc tgtacggcac
    10321 cgaaggcgtg ggcagccatg ccccagagga agaacgcggt caacagaagg aggagaccgg
    10381 gcgtcacctc ggcaccggcg agggccaaac cgacgacggc gggactcacg aagtgcgtac
    10441 tcgacgtcag cgagtccagg acggggcgtt ccttgaagcg gagtcccgcc acggagtagg
    10501 ccaccacggc gaaggcactc acggccaggc tcagccacac tgccggtccg ccggcgaagg
    10561 cgaggaccag caggaacggc acgttggtga cggcggcgag ccacagcatt ggccggtgca
    10621 gctggggccg gaggagtgcg ccttcgatgc cgcccttgcg cggattcttg aggtccgatt
    10681 cgtaatcaaa gacgtcgttg atgccgtaca tggccaggtt gtaggggatc aggaagtaga
    10741 acgtgcccac gatcaggacc cagtcgattt cgcgggtggt caggagcatg gccgcggcaa
    10801 acggatacgc ggtgttgatc caactgaccg gccgggacgc cagtattgcc tgcggaacca
    10861 ggcctgtgag gtcggatttt gctccggcac tccgacggcg ggtcagccac atccacagcc
    10921 cgggaagcac cacgacccct gccagcggat aggcgaaatc ctcgatgggt gccagcccgg
    10981 ccttcaagcc aagaatgtgc gaggcgtcgt agtggaaaag ctccatgccg atcatcacgg
    11041 agtcgaacac cgcggtcagc acagccaggg cggcgaacgc cagccccacg gctttccaat
    11101 gcctggaggc ttcgccctgc cgggcacccc ggcgggcaaa gatcacgccg gcgacggctg
    11161 ccgcggcgat gaaggcaagt gcgagccaca ggtacgtcat gcgttctccc gctcccgctc
    11221 cgcttgcctc gcgggagacc gttccagcaa ccgccgggcg cccgtgtaca ggaccatggt
    11281 gcacagggtc aggaagagca ggaacacggg ctcctcaatg ggcagttcgg gagcgatcaa
    11341 caggcccgtg gctatggttc cttcgccgcg gaggaaaatc cccagtccga ttccggctgc
    11401 gtcccagccg aggaagaaca aaaccccgac ggcggttacg atcgccgctg ccttcgcgtc
    11461 atgccagaag aacaggcgga atctgtgatc cagcagcagc atgcaggtga tgccgagcag
    11521 caacgaggcc aagtagagga ctcccatcag ccaatcctgc tggctacagg cctcacggtg
    11581 acagggccgg tgctgtgatc gccgcggatc ctcttcagca ccagctcggc gctgatcagg
    11641 cacatgggca cccccacgcc aggggccgtt gtggcgccgg cgtagtagag gccctgcacg
    11701 cgcttggagg cattctgggg ccggaacatg gcgctttgtc ccagtgtgtg ggccggtccc
    11761 agcatgcctc cgcgccatga gttgtagtca cgggcgaagt ccgctggtcc tgttgtctgc
    11821 cggaccacga tcctgtcgcg aaggtccggg atgcctgccc attgggcgat ctggtcgatc
    11881 gccgcgtcgg cggttcgttc tatgagcacg tctcccgccc cgtccggccc gccggctccc
    11941 agtgcgggat cggccgggat gggaaccagg acgaagaggt tctcgtggtc tgtgggcgct
    12001 acggcgggat cggttgcgct gggtttgcag acatagattg acgccgggtc cggaatggcc
    12061 gggttttcac cgaagatgga ggcgaagttt gcctcccaat cacgggtgaa gaacaaagag
    12121 tggtgcggca attcagggag cttgcccttg actcccagca tcaccaggac tgctcccgga
    12181 ccgctggtac gccgctgcca ccaggaaccg gggtagctgc ggtcccgcac gcccagcagt
    12241 tgggtttcgg tgtggtgcag atcggcgccg gagaccacga ggtccgccac gctgtagtgc
    12301 tcgttcccgg aggtgtcacg ccaggtcacg ccggtgactt cacggctgtc cctgccggtc
    12361 aaggcggccg gaagcttgac gccgtcgaac cgtcccacct tcttggtcct gctgacggcg
    12421 cgggtggtga tcttgagggc ctcggcgccg gtgtggatcc gaaccccggc ctggactgcc
    12481 agatcctcaa gccggcccac gagctcccag aagccgccca ttgggtattg caccccgtca
    12541 ccgaggtcca gcgcactcat caagtggtac atggcaggag catcggaagg gctggtgccc
    12601 aggaagacgg ccggataacc caggacctgc cgcagcacag gatgctggaa acgccgggca
    12661 acgtatttgt ccaggggcgt cagcagaagc tgcgcaagct tgggcaggct gcgcagcacc
    12721 tcgggttgga gcagtccttg caacctggtg aaggggttgt agaggaagaa gcgctccgcc
    12781 atgtcggtgg tgtgccgcgc cgatgccaga taggtggcca gcttcctggc gctgccgggt
    12841 tccacgtcct cgaacgtttc caaaacctgt tcgctgccca aggggacggt cagcgtgtcc
    12901 ggccggacgc cgtcgaggtt tggttcgctg aacacgcggt acgcgggact aagcgtgcgg
    12961 agatccaact gttccgcggt gctggtgccc agaagctcga aaaaatggtc gaagacgccg
    13021 ggcatcaggt accaggaggg gcccgtatca aagcggaagc cgtcgcgctc aaggctgccg
    13081 gcgcgcccgc caacgcggtc acgctgctca aggagttgga cttcgtgtcc ttcgtgggcg
    13141 aggagggcgg cggtggcaag cccagcgatg ccaccgccga tcactactgt ccgggtcatc
    13201 ggtgcagctc catccaggtt gaggtgactg cccgcgcggc aaggccggcc ttcacggcat
    13261 ccgggacgcg cacccgtgaa cggtagagct cgtccacggt ggtctgctcg atcctgtccg
    13321 tcagggctgt gaagagggaa agggcgctgc ggacagcggc ccgggcatcg cgcggcagca
    13381 aagggatgac ggcgtcggcg tcggccaact gggcgcggat ggtgcgtacc cattccacgc
    13441 ggtcgtggtc ctcaaggtgc tcggaggtgc ccaggtaatt gcgtcccaga cgggtggtgt
    13501 catcggccag gtcgcgcagg aaattgatgt tctggaaagc agcccccagc cggctggcgc
    13561 catgctgcaa agccgcggcg tcgccgtcgt cgatgttttc atcccgcatg aaaacgcgca
    13621 ggcacatcag ccctacaacc tcggcggagc cgtggacgta accctggtgg gcgtcggcgt
    13681 cgaaacgcag gggggtctcc ggggtcccgg tgcgctcgcc gaggtccgtg cgcatggagt
    13741 cgaagaacgg atcaatgagc gactcgtcaa tacgggccgc gcgggcagtc tgcgcgaagg
    13801 catggatgat gaggtcgctg ctgtagccca gcttgacggc ccggtgggtc tcgtcgatga
    13861 agtgggccag ggcatcgcac tgttcctggt agctgaggcc ggcctccgcg gtgacaccat
    13921 ccacgagttc gtccgcgacg cgcaccaagg cgtagatgtt ccggacatgt tggcggtgcc
    13981 gccgcccgag cagcttgcac gccagcccga acgaggtgga atatgcggcg atcacctggt
    14041 tggcggcccg ctcggccgtc cgggtgaaat gggtgaatga ggtgtctgag gcgaggctca
    14101 tgactgccgt ccttccaatt gcccggcaag gtccagcaac acattgcaca cgccctgcgg
    14161 gatggtgctg gtcagcagct cgttgaaggc ccgcatctgc tcctcgatga gtccgttgac
    14221 gaacgtttcc gccccgcaat cggccaagtg ccggcgaacg tattcgcatt ccgagccgtt
    14281 cagctccggc ctgccgaaga aaggctcaat gtccggccat gccgccgtgg ttcgtgcatg
    14341 ggcgatgatg gccgtttctt ttccctcccg cagatccgaa aagggatcct tgccgtgccg
    14401 gcgggggtcc ccgaacgttg acaggaggtc gtcctggagt tggaaggcga ggcccagatg
    14461 gcggccggcc gtggcgagcg cattttcgac ggcgaagtcc gcgcctgcca gcgcggctgc
    14521 ggcccgcagg ggaagttcga aggtgtaggt ggcggttttg tagccgcaca tcaccaggat
    14581 ggtctcgagg tgggggtcga tgatgccgtc cccgaggccc acgtccagct gctcaccggc
    14641 cactgtttca ttgatggtgt gttccaggag atccaggagc cgcagcctca gtgcatgcgg
    14701 gaggtcagcc ctggcgaagg cctggtgggt ggcggcgagg agcatgtccc ccatgaggat
    14761 gccgccggtt tgggcccagt ggaggtcgct gccttcccgg gcgccttcac cactgttggt
    14821 ccggggaagt gactgggttt ctgaaagcga ctttgcttct gcgaggaggg agccgatgag
    14881 gttcgggtgc ccgcgccgga ccaggtctcc gtcgatcacg tcgtcgtgga gcaggaaaga
    14941 gtagtggagg agttcgatcg cggccgcaat gctgatggcc gtttcgcggt ggcccgtgtc
    15001 cggcgggctg gcttggggct ggttggtgcg gggctggcct gtgccgtccg tgccgcgccc
    15061 cctgagggca tcgtaggtct ccatgagcag caagggacgc acgaactttc cacccaggac
    15121 gttgtggccg gccagttccc agagcctggt gaaatgcggc ccatacgttg ttgcggcggc
    15181 ggcccgcttg ccgatgagcc cgctgagctc gttctcaatc gccgtgcaaa ggtcggtgcg
    15241 gctgcgtaaa gcaccggagg tgacggtcat gctttggctc cggtcccgag ggggagtacc
    15301 cgcgcttcaa gcagctgagg gaactggagt cccaaccacg ggctgaaagc ggagggggtg
    15361 cgctccaggg agttggccag cagggccggt gacatccagg cccagtccgc tacctctgaa
    15421 ggattgggtt ttagatcgcc ggcgatcctg gctacgtaga ccgggcagat ttcgttttcc
    15481 acaattcccg tggggtccac ggccctgtac cggaagtggg ggagcgccat ttcaacctgg
    15541 ttggcatcca ccccgagttc gaattgcgcc cggcgggcta ctgcgtccaa ggggtcctcg
    15601 ccgggtgccg ggtgtccgca aaagctgttg gtccacactc cgggccaggt tttcttctcc
    15661 ggcgagcggc gggtcaggag aacctcgccg tcatcgttga ggaggtagca ggagaatgcg
    15721 aggtggaggg gcgtttcctg tgtgtggacc cctgctttgg gggcttcgcc tatgggtgtg
    15781 ccggcgtcgt caaggaggac aaccatctct gtagcgttca tactgcgcct tcctcctgca
    15841 acctgagtct ttacagcagc ccgaatattg ctagacaagc tagaagaaag gctaccatgt
    15901 aggaagttag gtgtaacata ctcagcatgt ccagtcttga agaaatgcct gatgaagccg
    15961 ggttcccggt ctcatccggc ctctatcatc tggacgccaa cgatccccat caacagttga
    16021 ttgaccgctc ccggttctcc gaagccgaca tcgaacagat cagcgaactc atggcagcgc
    16081 tcgggaggct ccgcgacgcc gaacagcgct tggcggaggc ttcactccgg tatatgaaac
    16141 tgaaccaatc ggacatgcgg gcgctgcatt acctgatcgt ctgtgccaac catggcgtca
    16201 tagccacgcc cggagccata gcttcccacc tgaacatctc gacggcgtca accaccaaat
    16261 tgctggaccg gctggaacgc gccggccacg tcacccggca ggcgcacccc tccgaccgac
    16321 gggccctcgc gatcgccatt accccggaaa cgcacgaagc cgcgatgcgt actgtgggca
    16381 agcaacaggc gaagcggttc ctggcggccg cacgcctcac tcccgacgag cgcgtggccg
    16441 tgatgcggtt cctcgatgac atggcgcggg agatcgaagt ggcggacgag ccctgggctg
    16501 cggctccacg ctgaaagctt cctgtgattc gaatgataag tgtgagccaa gtgacacttt
    16561 tctctgtaag attcgaggca aggccctcat gcggcgggcc ggcagttgtc tggcctggcc
    16621 agcgggggat acacaaagga ataattgatg gctcaagaag cgggctctct atcaccgggt
    16681 gacgacgcgg acagcagcaa ccacgacggc gcaggggaca cgccgttcgc ggatgaagtg
    16741 accatgcggg cacaggtcct ggacatcatc gagtccattc ttgaggacgc tgaaccgcgc
    16801 agtgaggggg ccaggaacaa gctccgtgag cttcttgacg cgcggccgga cgaccccgag
    16861 ggtgcattgc tgaagcacct gctcctcacc cggaaaacat cacagccggc gtccaacgtg
    16921 cctgttcact tggaacacgc cagcctgcat ctggaatcgt ccgacgcgtc acgaaccgtg
    16981 ctggtccctg tcagccacga cgtccgcgcc ggcatccaat cgatcctggc cgacaagctt
    17041 ctcctgacgg cgttccagcc gatccactcc cttcccaagg gcgacccaat cggcgtcgag
    17101 gccctgacaa ggttcatcgg tgaggacggt gcgggcgccg acgtgtggtt cagtgaagct
    17161 gctgctgccg gtctgggaac tgagctggag attgcagcgc tgcattgcgc cctgatggct
    17221 gcgcacgacg tcccggaaaa catgtttgtc actctgaatc tcaccccggc cacctcgcac
    17281 gatccccggg tgcggaacct tctggccgct gccgccttgg cccccgagag gatcatcgtt
    17341 gagctgacgg gcagcctgga atccatggcg gcccagccgg acggcgaagg cctcgaacaa
    17401 ctgcgggcct tggggttgcg ggtggcgatc agcgcctcgg gtgccgcatt ggtctcgctg
    17461 gacaggatcg agcaattgcg ccccgacatc atcaaactgg accgccacct gattgaagga
    17521 atcgccggaa acgacggcca gaagctccgc gccaaggcca tcgttgagct ggcccgtgag
    17581 atcggggcag atgtccacgc gcaaggcatc gaaacggccg aagaactgca cgaagtcacc
    17641 gccttgaagg tcaccgctgc gcagggatac cttttgggcc gtccctcggt gcacccgctt
    17701 gattggtcgg cctggagcgt ccgggcgcaa acggaaccgc agcctgccag ctgaccgtcg
    17761 ttgaatcgac gacgccggtc ctcgcccggg gtgccaggcg gcaggccgcg tggccggtca
    17821 gttgttcggc ggccggtcag tcagttgttc agtccgttat acggcgggga tcgttcccga
    17881 catagctgcc tggcggcatc gccgcaccga aaaccggccc gggctgtgga cgcttggggt
    17941 gccgaccgcc gtcggcgttc cgctgcgtca acctccgcac aacccaagga aaaaggtgct
    18001 cccgggccca cacgatgtca tccgcgcggg cctcgcgcca acggcgctcg ggaagcggcc
    18061 gcggagccag cggttcaagg gaatgcggga cgttcaatga ctccaggacc atgatggcga
    18121 tgatgtgctg gccgagcgga gagaaatgaa gccggtccgg atcccacatc cggggatcgg
    18181 tgagttggcg caaagcccag agatcggcaa tcacggcatc atgacgggcg gccaccacgc
    18241 ggatgttctc gttgaaaaca gccactttgc cgcgggtcct gccaagcacc ggggtcgcgc
    18301 cccagtccgg gccggtgaag aggacgatgg tggcgcccgt tgaggccagc gtttccacgc
    18361 cacgatccag ttccagtgcc agcttgtcgg ggtcgctcct atgaaagagc aggtcgttgc
    18421 cgccggcgtt gagagtaatg agatcgggtt tgaggtccaa tgccggaccc acttgctcct
    18481 ccaggatctg atggaggagc ttcccgctga tcgccaggtt ggcataggcg aaatcgtggt
    18541 ggtccgtact caactcttcc gctacacggt ccgcccatcc ccggagtccg cccgggctgc
    18601 ggggttcggg gtcgcccaga ccctccgtga acgagtcccc caatgccaca taacggctcc
    18661 acgggtgcag tccagcccgg aagctaccgg aaccgtcctg cgccaaaccg ccggcatcag
    18721 gagcgtccat ccctccatag tgcgccacat cctgaaaatg tgtgctgaaa cgggaattct
    18781 tttattcagc tgcggaacct cggtccgccg tccatttcgt gcgctgttgg gtacggtaag
    18841 cctatggctg cctcacgaaa gcgatcggac tccagctcca ccctgctgac cgtcgtcatc
    18901 gctttcgcgg cgaacgccct ggttgcagcg gccaaatcag tggccgccgc gctcaccggt
    18961 tcggcgtcca tgactgctga ggcggcgcac tcctgggccg acaccggcaa ccaggtgttc
    19021 ctgttcctgg ccgaacgccg ctcccaacgt ccgcgcgata cgggacatcc catgggttac
    19081 ggccgcgaag cgtacgtctg gtccatgttt gccgctttcg ggctgttcac tgccggcgcc
    19141 gtggtttcca tcatgcacgg gatccagcag atcattgagc cggagcctgc atccgacttc
    19201 ctgattgcgt acgtggttct ggcagtggcc tttgtcctgg aagggttttc cttcgtccag
    19261 gccttccgcc agacccgaaa ggcggccagg aagctggaac ggcggacctt ggaacaggtt
    19321 cttgtcagct cggatcccac gctgcgtgcc gtcttttcgg aggatgccgc agccctggtt
    19381 gggctggtga tcgcattcac tggcgtcttc ctccatcagg tcacgggttc gcccttgccc
    19441 gatgctgtcg gatcgattgt cgtcggtgtc ctcttggcgg ttgttgccgt cgttctgatc
    19501 gaccgcaacc gccggttcct ggtagggcag ggggtcacgc cggacataga acggtccatg
    19561 gggcggcagc tcctggaaca ccgggacatt gcacggctca cgtacctcca cctggaattc
    19621 gtgggccccc gcaagctcta tcttgtagcg gccgtggact tgcaaggcga ccacccggaa
    19681 cacgaggttg ccgtggtgct gcgcaggatc gagagggagt tggaggacca cgagactgtg
    19741 gaggaagcag tgctgacgct tgccaccccg gacgaatcgt ccctgcagtt gtaggaacgc
    19801 cgggttacga ccgcccggtc tccagcagcc gctccatctg ctcaccggcg tcactgcctg
    19861 gtgccggggt gtaaaccaca atgtgcaggt ccggccggtc cgacggcgat acctggtggt
    19921 gctccagctg cagcactccc actgcgggat ggtggaaaag gcgctctcgg gactcaaagc
    19981 caaggatgtc gtagcggtcc cagctttcct ggaattccgg gctggcctcc ttgagtcgtt
    20041 ccacctgata agcgacatcc ggatcaccca gccgctgacc cgtctctgca cgaaattcgg
    20101 cgaggaacct cttgctggtg acgtcccagt ccgggagcag gtcccggacg taggggtcgg
    20161 tgaagacgag ccacaaaagg ttcctgtcgg cggcgtcgaa agttccaatg ttcgggtaca
    20221 gcgcctcgta ggcgcggttc cacccggcca cgccccagtc cggtgaaagc gcatacgagg
    20281 gattgggatc caaggcgtcc aacaggcgct ggacatgcgc cggtgcatcg gcggcaaccg
    20341 gacccttggg aatggtggag gcgtatccgc ccaaggagag cacgtagccg agcccggtat
    20401 ccgaaaggtg cagggcccgt gcgatggact caaggacctg ccgggaaggg ctgatgtccc
    20461 ggccttgttc gagccaggtg taccaggtga cgctcacccc ggacaggaac gcgatctcct
    20521 cccggcgcag tccgcgctcg cgggaccgcc ccaccggggg cagcccgtag tcggagcgca
    20581 gggcctggtt gcggcgggtc ctgaggtaaa gccccagttc cttgcgcctc tcatctttca
    20641 cactgacaac actattactc tggtactttc actactagta gcagcaccgt cttccagggg
    20701 taacaaaacc ccagcaggat ggtacttatg cctgcactac gctcacgaac agtcacccac
    20761 ggccgcaata tggccggcgc ccgcgcactg ctgcgcgcct ccggcgtcgc caacacggac
    20821 atcggcaagc cgatcattgc cgtggcgaac tccttcaccg agttcgtccc cggtcacacc
    20881 caccttgccc ccgtgggccg gatcgtctcg gacgcgatcc tcgccgccgg cgcagtaccg
    20941 cgcgaattca acaccatcgc cgtcgacgac ggcatcgcca tgggccactc cgggatgctc
    21001 tactccctgc cgtcccgcga cctgatcgcc gactccgttg agtacatggt caacgcacac
    21061 tgcgcggacg ccctcgtatg catctccaac tgcgacaaga tcactccggg catgctcatg
    21121 gcagcgctgc gcctgaacat cccggtggtc ttcgtctccg gcggtcccat ggaggccggc
    21181 cgcgtgaccc tgaccgacgg ttccgtgcgt tccctggacc tggtgaacgc catcgccgac
    21241 gccgtggacg aatccatctc cgacgaggac atcaacctca tcgaagagaa cgcctgcccc
    21301 acctgcggtt catgctcggg catgttcacg gccaactcca tgaactgcct cgccgaggcc
    21361 atcggcctgg ccctgccggg caacggctcg gtcctcgcga cccacaccgc ccgcaaggcg
    21421 ctgtatgaga aggccggtgc caccgtcgtc gagctcgtga agcgctatta cgacggcgac
    21481 gacgactccg tgttgccgcg ctccatcgcc accgctgagg cctttgacaa cgccatggcg
    21541 ctggacatct ccatgggcgg ctccaccaac accatcctgc acctgctggc tgcggcccag
    21601 gaagccggcg tggagtacgg actggccgaa atggacgcca agtcccgcca ggtgccctgc
    21661 ctggccaagg tggccccgaa cgtcgccgga aacaagacct actacatgga agacgtgcac
    21721 cgcgccggtg gcatccccgc cctgctgggt gagctgaacc gcggcggcct cctgcacaag
    21781 aacgtccact cagtgcactc cgccgacctc gaaggctggc tggacgactg ggacatccgc
    21841 ggcggcaagg caacggaaga ggcgcaggca ctgtggcacg cggctcccgg cggcgtccgt
    21901 tcctcaacag cgttctcgca atcgaatgag tggacctccc tggacaccga cgccgagggt
    21961 ggctgcatcc gttccgtgga gcacgcgttc tccaaggacg gcggcctcgc tgtgctgcgc
    22021 ggcaacgtgg cggtggacgg tgccgtggtg aagaccgcag gcgtggacga gtccatctgg
    22081 accttcgagg gccctgccgt tgtgtgcgag tcgcaggacg aagccgtgga aatgatcctg
    22141 aacaaaacca tcaaggaagg cgacgtggtg gtcatccgct acgaaggccc ccgcggtggc
    22201 ccgggcatgc aggaaatgct ctacccgacg tcgttcctta agggccgggg attgggcaag
    22261 aagtgtgccc tcatcaccga cggtcgcttc tccggcggca cctccgggct gtcgatcggg
    22321 cacatttccc cggaagctgc ctccggcggc gccatcgcct tggtggagaa cggtgacatc
    22381 atcagcatcg atatcaccca gcgctcgctc cagttgcagg tttcggacga gatcctcgcc
    22441 gaacgccgcg agaagctcga agtcaacggc gggtataagc ccaagaaccg cgaccgccag
    22501 gtgtcgccgg ctctccgcgc ctacgcggcc atggcactct ccgctgacaa gggcgccgtc
    22561 cgggacgtct cgctggtgga aaacctctaa ggcctagcgc cgcgcctttt gcgcccgggc
    22621 cgcctgccgc cgtcgtgctt ttacaacgca cgacggcggc aggcggcctt tttctgctta
    22681 actgcggttg atgcgttatc cacatacaca gattggcgtg gttactgggg attggggccg
    22741 tgacaggctt gctttatggg gatcggaggg caggtggctg aagggcaggc ggagtcttca
    22801 tcagactccg cggtggactg cctcgaagac ggtattgatg ccctggatgg tgtgagggcg
    22861 tcgatccttg ctcaagcctc gatgttcgat ttcggcgagg cgagcgcttt cgccggcaga
    22921 gtcgaggata ttgcccggac cgtggagtac cttcagctcg tcgcagcccg ggccgtggag
    22981 cgaacccgca aggaagccgg aactgccgcg gtgctcgatg acgggtaccg gaacgctggg
    23041 gatttcctcc gtgcacggct gcggatcaca gccaaggaag cccggcgtcg cctggccctt
    23101 gcggacgccg tcctgcccgg cgtcggcatt gccggagagc cggtcccgcc gcagcgcgaa
    23161 cagctggcct ccgctgtggc cgacgcactg gtatccggcg gctcggccac cctgatcagc
    23221 acagcactgg accgcgtcca tcttctgacc gatcaggaca ccatcaccag gatggagaag
    23281 gacctcacgt ccacagccat ccagtccgac acggatttcg tttccacgac ggcccgccgc
    23341 tggatggatt tcattgacca agacggtgcc gaacccacgg aagaagtgct tcggcaactc
    23401 caaggtgcgt tcattcgaaa gccacgcttt ggcctgaatc atctcgaaat cttcgcaacg
    23461 gccgagcaat tcgagaccct caccaccgtc atgaacgccg ccacgaaccc ccgcctcgtt
    23521 gagggcgggg tgcgcaatac tggcagttct ggcggcccgg gagggagaaa tggcccaagc
    23581 cgcacggctg tccataccac ccagcgcggc gcggacacca ggggtcggag ttcagccgcc
    23641 caggtccgca ccccagaggg cagggtagcc gccaccgttc gcatggagcc cgcgaacggg
    23701 aggaacccga ttccggaacc gggtcgccgc tcccgcgccc agaaactcct cgacggtctg
    23761 gtcggtggct gcgcgttggc cctgagaacc ggtcagctac cagccaatgg cggcttgaaa
    23821 ccccaagtca tggtcaccat cgactaccgg gatctctttg accagctcca gagccacgct
    23881 gccaatcaac aaaccggcaa ccctgtgggc accggtgaaa ccgacccggg cacaagagcg
    23941 gcaggcaacg gcacaacagg cacaggcggc ctgcgaccca ggctcagcag cgcggtatca
    24001 accttccaag gacccatcca cccgaacgtc atccggaaga tcgcctgcga cgccgatatc
    24061 ctcccggtct tgctcggcac cgaaggccag gtcctcggaa ttggccggac cagccggatc
    24121 ttcccgcccc acatccgcaa ggccctccag gcccgcgacc aaggatgtgc tttcccggac
    24181 tgcaccatgc cggcgccttg gtgcgaagcc caccacatca cctactggtc gcaaggtggc
    24241 cccaccaaca ccgacaacgg cgtgctcttg tgctcacacc atcatcacgt catccacaag
    24301 gaacagtgga tgattgcgag cagaaacggc atcccgtggt tcatcccgcc ggcgcacgtc
    24361 gatcccagcc aagccgcccg acggaaccat caccacgcac cgctgcggac atagaccgcc
    24421 agccttcacg gccatggcgg gcgactgtca aaggcggcct accgatagag ctcggccagc
    24481 aatgcaacca cagcctgctg atcctggggc gggtcgttct tcagccacgc cacgtacacc
    24541 ggaaccatgg gtgcgtcacg caccggccgg taggcgactc cccggcgtcg atattgatgt
    24601 gccgtggagg ctgcagtgat gccccgcgcg gccccgctgc cgatcacggt cagccaatcg
    24661 tcgatgtcgt ggatagggat aacctccggg ggcttaccct gctccggcca taggtccagt
    24721 gttgtgctgc ctgtgcgcag gtccattgcc acgggcaatg tggcgatttg cgccaaagac
    24781 actgacctcc ttggggccag cggatcgtca gtggacatgg cgcagtagcg cttttcctcc
    24841 ccgacgcgca catgctcgac ggcggcggcc tgcgggagtc gtcgaaggat tgcgtaatcg
    24901 gtggttccat ccagcaggcc gccgcttggg gtgttggaac gggtgagttg aagcccggtg
    24961 tgcgggaagc gcaatttcca gcggtgttgg aattcggttg tgtgctcacc cagagccgac
    25021 cacgcgtaac ccatgcggat ctgccccgtt ccggcccggg catcccgttc aagatcggcc
    25081 aggagcgcga tgatcctgcg ggccttgccc agtgcgcgct caccggcggc tgtcagcccc
    25141 acgctgcggg tggttcgctc cacgatgcgt gtccccagtg cttgctcaag ggctgcgatg
    25201 cttcgcgaca cggcggcctg ggacattcga agctcgatgg cggcgtcggt gaacgtgcct
    25261 tgctccacta
//
