LOCUS       NZ_CP053549            22392 bp    DNA     circular CON 17-AUG-2024
DEFINITION  Paenarthrobacter sp. YJN-D chromosome, complete genome.
ACCESSION   NZ_CP053549
VERSION     NZ_CP053549.1
KEYWORDS    RefSeq.
SOURCE      Paenarthrobacter sp. YJN-D
  ORGANISM  Paenarthrobacter sp. YJN-D
            Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
            Micrococcaceae; Paenarthrobacter.
REFERENCE   1  (bases 1 to 4334173)
  AUTHORS   Zhang,M.
  TITLE     Comparative genomic analysis of iprodione-degrading
            Paenarthrobacters reveals the iprodione catabolic molecular
            mechanism in Paenarthrobacter sp. strain YJN-5
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4334173)
  AUTHORS   Zhang,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-MAY-2020) College of Life Sciences, Nanjing
            Agricultural University, Weigang NO.1, nanjing, jiangsu 210095,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.3 OR MAY-2019
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015040335.1-RS_2024_08_17
            Annotation Date                   :: 08/17/2024 05:55:21
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,216
            CDSs (total)                      :: 4,145
            Genes (coding)                    :: 4,122
            CDSs (with protein)               :: 4,122
            Genes (RNA)                       :: 71
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 23
            CDSs (without protein)            :: 23
            Pseudo Genes (ambiguous residues) :: 0 of 23
            Pseudo Genes (frameshifted)       :: 6 of 23
            Pseudo Genes (incomplete)         :: 18 of 23
            Pseudo Genes (internal stop)      :: 1 of 23
            Pseudo Genes (multiple problems)  :: 2 of 23
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:51:13
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 103546
            Orig. end                         :: 125938
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP053549.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22392
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="2"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22392
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22392
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12392](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12392)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            complement(214..870)
                     /locus_tag="HMI60_RS00505"
                     /old_locus_tag="HMI60_00505"
     CDS             complement(214..870)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020608533.1"
                     /locus_tag="HMI60_RS00505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_00505"
                     /product="YitT family protein"
                     /protein_id="WP_193590351.1"
                     /transl_table=11
                     /translation="MLTRRIAQLLAGLSLFGFSIAVLIKAGLGISPWDIFHQGLARLTG
                     ISTGMVIVAISFLVLLLWIPLKMRPGWGTLANAVLIGAFVDLSMPLIPQASGLLWQLVY
                     LAGGLVLLAVASASYLGASFGPGARDGLMTGLAQRTGWSIRNCRTLIEITVAAAGWLLG
                     GTLGIGTIAEAFLIGPLIQWLMPLFSVPSSRQDLSSPTIGSRTGRPASTTTTSNS"
     misc_feature    948..961
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.21"
                     /tool="antismash"
     gene            complement(1002..2795)
                     /locus_tag="HMI60_RS00510"
                     /old_locus_tag="HMI60_00510"
     CDS             complement(1002..2795)
                     /NRPS_PKS="Domain: NAD_binding_4 (13-239). E-value:
                     5.2e-23. Score: 73.4. Matches aSDomain:
                     nrpspksdomains_HMI60_RS00510_NAD_binding_4.1"
                     /NRPS_PKS="Domain: Abhydrolase_1 (374-584). E-value:
                     1.4e-16. Score: 52.8. Matches aSDomain:
                     nrpspksdomains_HMI60_RS00510_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018778401.1"
                     /locus_tag="HMI60_RS00510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_00510"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_193590352.1"
                     /sec_met_domain="NAD_binding_4 (E-value: 3.5e-21, bitscore:
                     73.4, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 9.4e-15, bitscore:
                     53.7, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 6.5e-10, bitscore: 36.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPHADSRNALVFGASGMVGRHLVLTLAKAGANVTAAVRTAESGA
                     RVERWVREHGLERSIRTTIVDFDAPGIVTGGPSTLPFITEIHNCAGTYRFGMTAQEARS
                     ANVGIVEKLIDFAKDLPNLQRVVHVSGYRVGGQDPATVPWSDDHRIAVYKELGAYEASK
                     VESDAIFQARALEHGVPWTIVNPSSLIGDSVTGESDQLIGLATTIAQIWEGAVAALPGN
                     GSTFLPVVTVDYLAAFMTAAAVDPTAAGKAYWVLDDATPPLADLLTHVGRHLGVKVPRV
                     RMPVGVIKRLPQRITRADPETLSFMSADRYPTESAIEFANRHGIQMPDVLVSLERWADY
                     LAAHRFGDALADGRRFVDAGGVRTFELGVAGSSRVVLPGLPVNADTWAGVASGVGARVV
                     DLPGLGLSGGTGIQDWERWLPDVLGGEPADLIGHSIGAAAAVVAADRFPERVKSLTLVA
                     PFFLQTPTGVPAGLRPLVSTYLRHTNPARLSRQLTGSEANAAALQSSLSDIKRSSAKKV
                     ARQLALAGSKQWRSELQEALGRFTGPVRIITGSEDPIAPGMVGQLESLPNVELVSMPGA
                     GHHPQLTHIDPLVTLITQSVG"
     aSDomain        complement(1044..1673)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HMI60_RS00510_Abhydrolase_1.1"
                     /evalue="1.40E-16"
                     /label="HMI60_RS00510_Abhydrolase_1.1"
                     /locus_tag="HMI60_RS00510"
                     /protein_end="584"
                     /protein_start="374"
                     /score="52.8"
                     /tool="antismash"
                     /translation="VVLPGLPVNADTWAGVASGVGARVVDLPGLGLSGGTGIQDWERWL
                     PDVLGGEPADLIGHSIGAAAAVVAADRFPERVKSLTLVAPFFLQTPTGVPAGLRPLVST
                     YLRHTNPARLSRQLTGSEANAAALQSSLSDIKRSSAKKVARQLALAGSKQWRSELQEAL
                     GRFTGPVRIITGSEDPIAPGMVGQLESLPNVELVSMPGAGHHPQLTH"
     aSModule        complement(1044..2756)
                     /domains="nrpspksdomains_HMI60_RS00510_NAD_binding_4.1"
                     /domains="nrpspksdomains_HMI60_RS00510_Abhydrolase_1.1"
                     /incomplete
                     /locus_tags="HMI60_RS00510"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       complement(1464..1520)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HMI60_RS00510_0001"
                     /evalue="8.60E-04"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="HMI60_RS00510"
                     /protein_end="444"
                     /protein_start="425"
                     /score="11.2"
                     /tool="antismash"
                     /translation="EPADLIGHSIGAAAAVVAA"
     aSDomain        complement(2079..2756)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HMI60_RS00510_NAD_binding_4.1"
                     /evalue="5.20E-23"
                     /label="HMI60_RS00510_NAD_binding_4.1"
                     /locus_tag="HMI60_RS00510"
                     /protein_end="239"
                     /protein_start="13"
                     /score="73.4"
                     /tool="antismash"
                     /translation="GASGMVGRHLVLTLAKAGANVTAAVRTAESGARVERWVREHGLER
                     SIRTTIVDFDAPGIVTGGPSTLPFITEIHNCAGTYRFGMTAQEARSANVGIVEKLIDFA
                     KDLPNLQRVVHVSGYRVGGQDPATVPWSDDHRIAVYKELGAYEASKVESDAIFQARALE
                     HGVPWTIVNPSSLIGDSVTGESDQLIGLATTIAQIWEGAVAALPGNGSTFLPVVTVDYL
                     AAFM"
     gene            2789..2995
                     /locus_tag="HMI60_RS00515"
                     /old_locus_tag="HMI60_00515"
     CDS             2789..2995
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HMI60_RS00515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HMI60_00515"
                     /product="hypothetical protein"
                     /protein_id="WP_193590353.1"
                     /transl_table=11
                     /translation="MSSRPPGGLATLVDKLRYRTSSRSKGLGALPGARGYGRSLRRRHK
                     NGYRRPRVFGVNTAGLDGLEQGL"
     gene            complement(3179..3745)
                     /locus_tag="HMI60_RS00520"
                     /old_locus_tag="HMI60_00520"
     CDS             complement(3179..3745)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018778399.1"
                     /locus_tag="HMI60_RS00520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_00520"
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="WP_018778399.1"
                     /transl_table=11
                     /translation="MSEHNIAGKKVAFLLTDGVEQVELTSPWQAIKDAGGEPTLVALDK
                     GKLQGFNGVDKGDTFDVDLAVADANASDFDALVLPGGVVNADNLRVDKDAQNFTRSFFE
                     QHKPVASICHGPWILIEAGVIKGRNVTSYHTLQTDLKNAGANWSDEEVVCDQGLVTSRN
                     PDDLPAFNAKVVEEISEGQHAGQTA"
     misc_feature    complement(3729..3745)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 19.26"
                     /tool="antismash"
     gene            complement(3990..4787)
                     /locus_tag="HMI60_RS00525"
                     /old_locus_tag="HMI60_00525"
     CDS             complement(3990..4787)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HMI60_RS00525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HMI60_00525"
                     /product="hypothetical protein"
                     /protein_id="WP_193590354.1"
                     /transl_table=11
                     /translation="MTTLVDTARTPSLFRAELTKLVTLRSVWITAALTWLIVVLVGWSQ
                     AGPVGEALRTNDPGLAPGASPETVGFDWVALGLIGIIVIGVISASSEYVSGQLRTSLVA
                     APNRERLYLAKCTALTAFVTLLGLVTIPLLSLLSQSGLGELSVVNGSVPASLILRWAGA
                     IAFWDAIALIGFALGILLKQTLIPLFALIVVSQLSLMLLLLTPSFAYLPTVAGVLLFDP
                     GLVTGSYPAADLGALTAAIVTFTWTAGLVGFAGFKFSTRDARG"
     gene            complement(4784..5482)
                     /locus_tag="HMI60_RS00530"
                     /old_locus_tag="HMI60_00530"
     CDS             complement(4784..5482)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012865386.1"
                     /locus_tag="HMI60_RS00530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_00530"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_227453621.1"
                     /transl_table=11
                     /translation="MSKKYGQSDGIIDVSLTAEPGKVTAFLGPNGAGKSTTFRLLLGLD
                     RADSGSALIEGKPYRDLIAPLWTVGAQFDGSGAHKGRTAKAHLTWLAQSNGIPHSRIGE
                     VLELVGLADAARKRVGAYSLGMGQRLGIAAALLGDPRIIVLDEPTNGLDPEGIRWIRGL
                     LRTLASNGKTVLISSHLINEVQHVADHIVVISGGRIVQSGNVVDLVAGHHDLEAAYFDW
                     TGNAAKGSAA"
     gene            complement(5530..6351)
                     /locus_tag="HMI60_RS00535"
                     /old_locus_tag="HMI60_00535"
     CDS             complement(5530..6351)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HMI60_RS00535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HMI60_00535"
                     /product="hypothetical protein"
                     /protein_id="WP_193590356.1"
                     /transl_table=11
                     /translation="MPASSTATLDVRPGLRTTMARAVRAETTKLLTLRLCLNTMAGTVL
                     LTVFLSWILTNLIDAAHKAGRPEEAAGLEGGTAFLVILHYGQIGVILLAAWSMHQESDS
                     GSLRSTLISLPQRSAVLAAKAIVIVAAVFITAVLSVFGSAGIRCAVIDCTTETSQIAAT
                     PQAASGILWGVVLYWILIALFTYALSVVLRSGLAAMGTVLAMALIVSTYMVNITPLAKF
                     LPDQAGAQLYQLPPSAPDDLGPATGGLVLVVWVVAALVAALVLFRRQPVRR"
     gene            complement(6417..7070)
                     /locus_tag="HMI60_RS00540"
                     /old_locus_tag="HMI60_00540"
     CDS             complement(6417..7070)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018778395.1"
                     /locus_tag="HMI60_RS00540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_00540"
                     /product="response regulator transcription factor"
                     /protein_id="WP_193590357.1"
                     /transl_table=11
                     /translation="MNEISVLIADDDAHIRTSLRLLIDDEPDMTVSAVAVDGAEAVESI
                     LEHQPDVALMDVRMPRMTGLEAAGILASRKSSTRLVMLTTFDMDDYVYQALRQGASGFL
                     LKNAPLPDILKAIRTAHEGNALLAPEITRRLIDRFTQSPAAHDRISELTVRERETLTLI
                     GQGASNNEIAAALFLTRTTVRTYVSRILTKLDARDRAQLVVIAYEGGLVGPSPV"
     gene            complement(7067..7939)
                     /locus_tag="HMI60_RS00545"
                     /old_locus_tag="HMI60_00545"
     CDS             complement(7067..7939)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="HMI60_RS00545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_00545"
                     /product="sensor histidine kinase"
                     /protein_id="WP_193590358.1"
                     /transl_table=11
                     /translation="MTEDPFLVTGLCLYVAAERFGTRLFPAWLIVLEILLFASLLLVSA
                     EGAEASIRGIILGAVIIGAAWVLGIRTQRMRCETERNARAQERLRLARDIHDVLSHTLG
                     GIGVRAGVVAHVKSSTPDDLRSALQGIESDARDALGQLQVLMRQERSETADDAPPGSLP
                     ELVRELSQPAIRAGISVVIDADESAHDLPAAQRTTAYRIIQEALTNVIRHSGAGTCRIT
                     IRTEGDDLRISVLDDGPGAALASKNGHGLTGMRERAQLLGGTFEAGRETNGYRVAVSLP
                     GTAGRAHSR"
     gene            complement(8184..10004)
                     /locus_tag="HMI60_RS00550"
                     /old_locus_tag="HMI60_00550"
     CDS             complement(8184..10004)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018778393.1"
                     /locus_tag="HMI60_RS00550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_00550"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_193590359.1"
                     /transl_table=11
                     /translation="MKTAANASRRAGLTELFRHVAVQRRLVALIVLLSLLGSALSLAQP
                     LLVREVIDRVSASKPLDLLPWLVGGLILVGGVLGGIRQYLIQRTAETAIRRSRHNLIDH
                     ILHLPVPTLDQRRVGDLVARVTTDTTVIRNMLSQGFVESFAGVFTIIGALVAMLFLDPV
                     LVIIALGAALVSVAAVVWVTSYIERASLGVQTALGKLSSSMDRAIRATRTVRAANASTR
                     ESQRVKEDANGVWTIGLRVAATTALVSPISSIAMQVTFLAVIGVGGLRVASGELTVADL
                     VSFILFLFLLIMPLGQLFGTVSAIGEALGGVARINEILQLPTEQDAPVVVGNVVPTIRD
                     SSLVFRGVSFEYDHPSGETEGPSLRSTLSDVSFQIESRQRVAIVGPSGAGKSTILNLIA
                     RFYDASDGQILFGGTDVDQVARSAVRANIAYVEQDAPAVAGTLRDNLNIGNPDASDKDM
                     MAILERLNLTAVLQRSELGLDAEVGEGAVLLSGGERQRIAVARALLANPSMLLLDESTS
                     NLDGVSEEKVRELIADVTSGCTLVIVAHRLATVQSSDLILVLDEGKVVASGTHTELMQT
                     SPLYRELAQNQFLTNEMAYEPTTPEHDAKR"
     gene            complement(10001..10432)
                     /locus_tag="HMI60_RS00555"
                     /old_locus_tag="HMI60_00555"
     CDS             complement(10001..10432)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="HMI60_RS00555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_00555"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_110504859.1"
                     /sec_met_domain="PF13471 (E-value: 4.4e-23, bitscore: 79.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLPISPQPTVMPQGLFRLRTHAVVGVAWVMTLLPPALLQSVLHG
                     LSHSHRSTNAHQARLMRAAVCAVSARCAGEGCLQRSIAAFMLCRMEGHSPGWKTGYQLE
                     PFAAHAWIEVDGLPIDEPHRIRSYVPVLTVAQPGEASNK"
     gene            complement(10429..10731)
                     /locus_tag="HMI60_RS00560"
                     /old_locus_tag="HMI60_00560"
     CDS             complement(10429..10731)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.4"
                     /locus_tag="HMI60_RS00560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_00560"
                     /product="PqqD family protein"
                     /protein_id="WP_081623356.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.3e-16,
                     bitscore: 58.3, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.1e-10, bitscore: 38.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKKTTRTVEAGDVFRPSPKITFNVDDDGVTVFDARGGTYWRGNA
                     TAADVMAGIEQNLNVGAVVDRISESYGVDHHRVRQDVHALIDELQQSGIIRRASS"
     aSDomain        complement(10441..10689)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_HMI60_RS00560_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="9.10E-19"
                     /identifier="RREFam002.1"
                     /label="HMI60_RS00560"
                     /locus_tag="HMI60_RS00560"
                     /protein_end="97"
                     /protein_start="14"
                     /score="58.3"
                     /tool="antismash"
                     /translation="FRPSPKITFNVDDDGVTVFDARGGTYWRGNATAADVMAGIEQNLN
                     VGAVVDRISESYGVDHHRVRQDVHALIDELQQSGIIRR"
     gene            complement(10728..12392)
                     /locus_tag="HMI60_RS00565"
                     /old_locus_tag="HMI60_00565"
     CDS             complement(10728..12392)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.4"
                     /locus_tag="HMI60_RS00565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_00565"
                     /product="asparagine synthase"
                     /protein_id="WP_193590360.1"
                     /sec_met_domain="Asn_synthase (E-value: 3.5e-30, bitscore:
                     103.7, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQLFLANRGSASGLIDESSASLSSAAVTILDSRLSERQMRDSVV
                     SHQHLRAAPGAIPGYARDITGSISTAETLYWTDIDGTPVASMSQGALRRIAHSKLDDSR
                     VRLALCTNLPGFLRHLPFWEGINAVKPGSTLTYHDGRPKVLDQAIATEHPKLDLSEAAE
                     LLLAELTRSMERRILSYGKLSADVSGGMDSTSLAYILDSLQEESIYYHAGTDDPHNRDS
                     QYARRAASELRGQFTELESLTATSGAFSEFDQNIRSLDDGPLAWAGNSKHLGFLLTDAS
                     RRGVKAHLTGVGGDELFDPLPTTALDLLTTSSWRAGLRIIRRLGKMQRWSTLAVARAVG
                     SNVNFETEMLRRIEARAGNIVGPAEAFSWAPGFGISKFATAETREVVAQKVKDALTQGA
                     RPHHKDRFRHQMTEAVMFQGEVVRQVGHAYEHLGVAWEAPFLDDAVVRLILSLPTDILV
                     GTRDSKPLLARATEPVAPRWLFTREDKGEYSSDLFTEYKKRRHDLSRLFDESYLVDMGH
                     INADAVRDALSMPVVSTDELFEIEQLAGVERWVRAIQ"
     gene            complement(12496..12633)
                     /locus_tag="HMI60_RS00570"
                     /old_locus_tag="HMI60_00570"
     CDS             complement(12496..12633)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033521.1"
                     /locus_tag="HMI60_RS00570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_00570"
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_018778389.1"
                     /transl_table=11
                     /translation="MMMKSNYSAPRVARVGSFREVTNGVWFGRWRDIFGGRAFVKVDVG
                     "
     misc_feature    complement(12740..12753)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.6"
                     /tool="antismash"
     misc_feature    complement(12823..12838)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.31"
                     /tool="antismash"
     gene            12929..13516
                     /locus_tag="HMI60_RS00575"
                     /old_locus_tag="HMI60_00575"
     CDS             12929..13516
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011689739.1"
                     /locus_tag="HMI60_RS00575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_00575"
                     /product="recombinase family protein"
                     /protein_id="WP_193590361.1"
                     /transl_table=11
                     /translation="MGVFGKLDRRNISIGYARESTLGPSLADQVRMLKAAGAVDVYEER
                     ATGATELREQWGACYKVLQPGDSLLVSDLTRLGRSTSDLAGIMALLAQRSVSFRVVGEP
                     WLDTDGQYGPVILKLFESIANYERSRLSERTTVGLAAARARGRLGGRPPAMTPHKLETA
                     RNLRSKKLTLSEIADTLGVSTSTVARALSGPL"
     gene            complement(13822..15177)
                     /locus_tag="HMI60_RS00580"
                     /old_locus_tag="HMI60_00580"
     CDS             complement(13822..15177)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018778387.1"
                     /locus_tag="HMI60_RS00580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_00580"
                     /product="uracil-xanthine permease family protein"
                     /protein_id="WP_018778387.1"
                     /transl_table=11
                     /translation="MSMLGTKWKLHGNGKSIRPGHVVAPDERLAWPLTIGIGMQHVVAM
                     FGATFLVPIITGMPPATTLFFSGIGTLLFLVITKGRVPSYLGSSFAFIAPIMASQQQYG
                     VGGALGGVVLAGVVLALIGAVVQKFGAEWINRLMPPIVTGAIVALIGLNLAPAAKANFD
                     LAPVTALITLVTIILVSVLFRGILGRLSILVGVVVGYLVAMMRGEVSYEKMDAAAWVGL
                     PFFQTPEFHIGVVGLFVPVVLVLVAENVGHVKSVAAMTGQNLDGVSGRALMADGAATVL
                     AGFGGGSGTTTYAENIGVMAATKVYSTAAYWVAGVFAILLSFSPKFGELIATVPPGVLG
                     GAATMLYGMIGVLGVKIWVQNKVNFSNPINLTTAAVALIIGIADYTWTIGELKFTGIAL
                     GSAAALVIYHGMKGLARWRGTVAEPETETAGLPPAVKSAMNAAAKRGGKKGK"
     gene            complement(15258..17735)
                     /gene="opgC"
                     /locus_tag="HMI60_RS00585"
                     /old_locus_tag="HMI60_00585"
     CDS             complement(15258..17735)
                     /codon_start=1
                     /gene="opgC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018778386.1"
                     /locus_tag="HMI60_RS00585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_00585"
                     /product="OpgC domain-containing protein"
                     /protein_id="WP_193590362.1"
                     /transl_table=11
                     /translation="MPTFPLAAPRRALAVLVLLLLAFLLPSTQAWALDRQPADGDDPGQ
                     RYFGTLLDWDKDSAADYAQRLGEPAALYGQNVSMPMDEGGLDYLRDYFSQVAGQGSHAL
                     LTVRPGISLRDVSDDAAATFARQITTAAAGFRGKVFVRFAPEMNAPWVAWGQEPEAYRA
                     AFGRVAAALKSSLADPVMVWSPTAEKDYPFQTATSTPPKGVPLASLDTNANGVWDLDDS
                     AFDPYYPGDDVVDWIGLSIYHDTTGAGSAQNTLPAADEFNDSLHASSGGTGTDNFYGTY
                     AQARNKPLLIETGAFYSPGAGGAAEIDVKQTWWHQVFASVAQPENGSVRAVVWNETTDA
                     RDQSKVSIDWRATAQPLLAAPFRTSLDTSGLRVGPVTEKGLKDVPGLEIPQAKSDTVIR
                     GWAAWATAGTVLVAVAALWLLSSRAAPNKWSYTGSGRRDARIDMLRGLAIVFVVVNHVG
                     INSVFQLLSQETIGVVSGAELFVMLSGVVLGMVYGPRISTELGDVVDGTTKRAWKLYFT
                     ALAVVLIVYGLSLLPFINAAAVTTFTDQGTGAAGHSAAGTTYDLYAGMEGLLQFPVPQG
                     LIPALLLLQVGPWQFNIMGLYVILLLISPLILVALSRGLTWPVLTVSLALYIGGSVFRF
                     RLLPSQFEDSFPLLVWQLLFVLGMTAGFHRQRIIDWFAHPRQRILLGVCVFLAAACALF
                     SWSGPYLTNQLDVRLALIPETTFRYLYDTFFGRTYLGPGRVVNVLVITIALYALLSAFW
                     KPLSRAVGWFFIPLGQATLYVFIMHVFFIVAIANIPALRDGNLWLNSAVYAALLAILWV
                     MVKTKFLFKLVPR"
     gene            17941..18546
                     /locus_tag="HMI60_RS00590"
                     /old_locus_tag="HMI60_00590"
     CDS             17941..18546
                     /EC_number="1.1.1.298"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1159: dihydropteridine reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017198231.1"
                     /locus_tag="HMI60_RS00590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_00590"
                     /product="malonic semialdehyde reductase"
                     /protein_id="WP_018778385.1"
                     /sec_met_domain="PF00881 (E-value: 5.7e-10, bitscore: 37.4,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIAHEEAVIDAAAVDAIFAEARTANSFSGEVTEEQARAIYELTK
                     FGPTAFNSQPLRVTYVRSDEARAKLVDHLSRGNQAKTASAPLVAILSYDTDWQGQWDKF
                     LPEYGAPKAMYDADPAFAASTGNNNAHLQAGYFILAVRSLGFAAGPMTGADFAAIDAEF
                     FPAGDQKSFLVVNIGQPGPDAWGEAKPKFAYDDVVRTV"
     gene            complement(18647..19132)
                     /locus_tag="HMI60_RS00595"
                     /old_locus_tag="HMI60_00595"
     CDS             complement(18647..19132)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024124.4"
                     /locus_tag="HMI60_RS00595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_00595"
                     /product="DUF3806 domain-containing protein"
                     /protein_id="WP_193590363.1"
                     /transl_table=11
                     /translation="MSGPLIEEMSPAEEEWIQDLLRSFQQVGSAVDGPGSDHPRTDLEY
                     IDALWQMTVNHVEDEPDFDPNAMINIMGAALGDHLIREVPGLRWVLGTYPDGVTEATVH
                     HQTGNIVVHPMNFIGKRWPARSEEPGTWISQQAAGLVQGIQGALAAASGGTNAAQNS"
     gene            complement(19132..20802)
                     /gene="pgm"
                     /locus_tag="HMI60_RS00600"
                     /old_locus_tag="HMI60_00600"
     CDS             complement(19132..20802)
                     /EC_number="5.4.2.2"
                     /GO_function="GO:0004614 - phosphoglucomutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pgm"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018762688.1"
                     /locus_tag="HMI60_RS00600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_00600"
                     /product="phosphoglucomutase
                     (alpha-D-glucose-1,6-bisphosphate-dependent)"
                     /protein_id="WP_026267259.1"
                     /transl_table=11
                     /translation="MASRAGTVALPQDLVDITALLDAYFDVAPDLGDPAQRVAFGTSGH
                     RGSSLKASFNEPHILAITQAIVEYRGRQGITGPLFIGRDTHALSEPAQNSALEVLAANG
                     VTVLVDARHGYTPTPALSHAILKYNREAAPGTPQADGIVVTPSHNPPGDGGFKYNPPHG
                     GPADTDATGWIADRANQLLENGLRGVKRMPLNDALAADTTGKFDFLSSYVDDLPSVLNL
                     DAIREAGVRIGADPMGGASVDYWGEIGERHQLNLTVVNPTVDPQWAFMTLDWDEKIRMD
                     CSSPSAMASLIKRMSDSTGSSGAGSAFDIATGNDADADRHGIVTPDGGLMNPNHYLAVA
                     IDYLYRNRSGWNPDSVVGKTLVSSSIIDRVAAGLGRKLVEVPVGFKWFVPGLLSGEGAF
                     GGEESAGASFNKLDGSVWTTDKDGILLALLASEITAVTGKSPSQLYKGLTDQFGAPVYA
                     RIDAAATREQKAKLGKLSAADVTATSLAGEEITAKLTEAPGNGASIGGLKVVTENAWFA
                     ARPSGTEDVYKIYAESFKGADHLKQVQEEAKALVDGVIA"
     gene            21054..21761
                     /locus_tag="HMI60_RS00605"
                     /old_locus_tag="HMI60_00605"
     CDS             21054..21761
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018778382.1"
                     /locus_tag="HMI60_RS00605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMI60_00605"
                     /product="DUF4190 domain-containing protein"
                     /protein_id="WP_193590364.1"
                     /transl_table=11
                     /translation="MSDQPSKGNEDKPAGYEPPQYVPPAQFSAPEQNPPAPGAPVPPAP
                     GAPVPPAPGAPVPPAFEPPAQSFDQGNATQPLPPYEQNAYGQQNTYGQQNTYGQPGNQD
                     AYTPGDYSQQPASPYGQPPSPYQQQAFGQQPYGQPQSPYGQPAYYATPTQPKGLSIASM
                     VCGIAVYIGFGFFILPQIAAVILGHLALKREPAGKGMAIAGLVMGYLGIALTVVFGIIF
                     FAAIGASTNRYNY"
     misc_feature    22181..22195
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.74"
                     /tool="antismash"
ORIGIN
        1 gtccaaggag cgggagattc gcaatgcagg cggcacgtgg attgggccaa caattgttgt
       61 gttgtaccca gggttccgac ctgaggagcc aggaaagccg caagtagaag acagtgacgg
      121 aagggcgctc cgtggacttt cttgccgcca ccaacacttg tgtgagcaca cccgcggggt
      181 acgacgaaca catcgtttgg acccagtagg agtttacgag tttgatgtcg tcgtcgttga
      241 tgctggtcgg ccggttcggc tgccaatggt cggagatgag aggtcttgac ggcttgaagg
      301 aacactgaac aagggcatga gccactgaat cagcggtccg atcagaaacg cttcggctat
      361 ggtgccgatc ccgagggttc cgcccagcag ccagccagct gcggcgacag ttatctcgat
      421 caatgtgcgg cagttgcgga tcgaccagcc ggtccgttgg gccaggccgg tcatcaaccc
      481 gtcccgtgcg cccgggccga aggaggcccc aaggtagctg gcgctggcga cggccaggag
      541 caccagtccc ccggcaagat agacgagttg ccagagaagc ccgctggctt gcggaatcag
      601 aggcatcgac aagtcgacga aagcgccgat caggacggcg ttcgccaggg tgccccagcc
      661 tggccgcatc ttcagtggga tccacagaag gagcaccaga aagctgattg cgacgatgac
      721 cattccggtg ctgatccccg tcagccgagc cagaccttgg tggaagatgt cccatgggga
      781 gatcccaagc ccagccttga taaggactgc gatggaaaag ccgaagagcg acagtccggc
      841 aagcaattga gcgattctgc gtgtcaacat cacctcagca tcccctgaac tggctttgaa
      901 atatgtagcc agtttgaacc tctggctatc ttcctggtca gagctcgttg acggatctca
      961 atcggcatgt gtatttctca acatggaccg ggggcccctg ttcacccgac ggattgcgtg
     1021 atgagtgtga cgagtggatc tatatgagtc agctgcggat ggtgccctgc gcccggcatc
     1081 gagacgagct caacgttcgg aagtgattcg agctgcccaa ccatgcccgg ggcgattggg
     1141 tcctcgcttc ccgtaatgat gcggaccggg ccggtgaatc gccccagggc ctcctggagt
     1201 tcgctacgcc actgtttcga tcctgcaagg gcgagttgcc tggccacctt cttggcgctg
     1261 cttcgtttga tgtcactgag gctggactgg agagcagccg cgttcgcttc tgatccggtc
     1321 agttggcgtg acagccgcgc cggattggtg tgtcgcaggt aggtggatac gagcggccga
     1381 agcccggctg ggacgcccgt tggggtttgg aggaagaacg gtgcgaccag tgtcagggac
     1441 ttgacccgct ccgggaaccg gtccgccgcg accactgccg cagccgcgcc gatggaatgg
     1501 ccgatgaggt cagcaggttc accgcccagc acatcgggaa gccaccgctc ccagtcctga
     1561 atgcctgttc ctccgctgag gccgagtccg ggaaggtcga cgacgcgcgc gccgacaccc
     1621 gaagcgacgc cggcccatgt gtctgcgttg accggcaagc cggggaggac cacccggctg
     1681 gatccggcta ctccgagctc gaatgtcctt acaccgccgg cgtcgacgaa tcggcggccg
     1741 tcagccaagg cgtcgccaaa ccggtgtgcg gccaagtagt cggcccaccg ttccagggac
     1801 accagtacgt ccggcatctg tatcccgtgt ctgtttgcga actcgatggc tgactctgtc
     1861 ggatagcggt cggcggacat gaaggaaagt gtctcgggat ccgccctggt gatccgctgc
     1921 gggagtcgct tgatgacgcc gaccggcatc cgtacccgcg gaaccttgac tccgaggtgc
     1981 cgcccgacgt gggtgagcag gtcagccagc ggcggggtag cgtcgtcgag aacccaataa
     2041 gccttgcccg cagcagtggg atcgaccgct gctgccgtca tgaaggcagc caagtagtcg
     2101 accgtgacga ccgggaggaa cgtcgatccg tttccgggca gtgcggccac ggctccctcc
     2161 cagatttgcg cgatggtggt agccaggccg atgagctggt cggactcccc ggtcacgctg
     2221 tcgccgatca ggctggacgg attgacgatc gtccagggga ctccgtgctc caaggcacgt
     2281 gcttggaaga tggcgtcgga ttccactttc gacgcctcgt aggcgccaag ttccttgtag
     2341 accgcgatgc ggtggtcatc tgaccatggg acagtggcgg ggtcctgtcc gcccacccgg
     2401 tagcccgaca cgtggacgac gcgctgcagg ttggggaggt cctttgcgaa gtcgatcagt
     2461 ttctcgacga tgccaacatt tgcgctgcgt gcctcctggg cggtcatccc gaatcggtag
     2521 gtcccggcgc agttgtggat ctcggtgatg aacggcaatg tcgatggtcc acccgtgacg
     2581 atcccgggag catcgaagtc gacgatcgtc gtcctgatgc tacgttccag gccatgctcc
     2641 ctgacccatc gctccacacg cgctccggac tcggcggtcc ggactgccgc agtcacgttc
     2701 gcgccagcct ttgcaagggt caggacgagg tgccggccga ccattcccga ggccccgaag
     2761 accagggcgt tgcgggagtc tgcgtggggt gtcatcgcgt cctcccggcg gtctggcaac
     2821 gctggttgac aagctccgct accgcaccag cagccgcagc aaggggttgg gtgctctgcc
     2881 tggtgcgaga ggctatggtc gcagtctccg ccgacggcac aagaacggct accggcggcc
     2941 gcgcgtcttc ggcgtcaaca ccgctggtct ggacgggctg gagcaggggc tctgagagcc
     3001 gttctcttgt cagggttcct ttggatggca tgaagaaata atagaccagt ctatatattt
     3061 tgcaaatcac tcaagtgccc gggcgaacga gccttcctgg cagttaaacg caagtgccgc
     3121 cgtcgtactt cttgtgaaag tacgacggcg gcactcgcct taaggacgct ggtggccgct
     3181 aagccgtctg gccggcgtgc tggccttccg agatctcttc aacaaccttg gcgttgaagg
     3241 cggggaggtc gtccgggttg cggctggtga ccagtccctg gtcgcacacc acttcttcat
     3301 cgctccagtt ggcgccagcg ttcttcagat ccgtctggag cgtgtggtac gaggtgacgt
     3361 tgcggccctt gatcactccg gcttcgatga ggatccacgg tccgtggcag atcgaagcca
     3421 cgggcttgtg ctgctcgaag aaggagcgcg tgaagttctg ggcgtccttg tccacgcgga
     3481 ggttgtccgc gttgacgacg ccgcccggga gaaccagggc gtcgaagtcc gaggcgttgg
     3541 cgtccgcaac tgcgagatcg acgtcgaacg tgtcgccctt gtccacgccg ttgaaaccct
     3601 ggagcttgcc tttgtcgagg gctaccaggg tgggctcgcc tccggcgtcc ttgatggcct
     3661 gccacgggct ggtgagttcc acctgctcca cgccgtccgt caaaaggaat gcgaccttct
     3721 tgcctgcgat gttgtgttct gacattgttc ctcctcttgt tcggctgctt tttgggcatg
     3781 tgccggtgct gcgagagttg tttgtctgac ctgaaccagc ctagggaagg atgctttagt
     3841 aagcaagctg actatttcga tggcgttggt gaacatacgc ctaaccggac atattcagtc
     3901 gcagcgaaaa ccggcctcga acgtcgctaa gccaagcccg acggcggtcc ccgcctcagt
     3961 ctgaggtgag gaccgccgtc gtggttcagc tatccgcggg cgtcccgcgt gctgaacttg
     4021 aaccctgcaa aacccacgag gccggctgtc caggtgaagg ttactatcgc agcggtgaga
     4081 gcacccaggt ccgcggccgg gtatgacccc gtcaccaagc cgggatcaaa cagcaggacc
     4141 ccggccactg tgggcaggta ggcaaaagac ggagtcagca agagcaacat caacgacagt
     4201 tgcgacacta caatcagcgc aaacagcggt atcagcgtct gcttgagcaa gatgcccagc
     4261 gcgaacccaa tgagggctat ggcatcccag aaagcgatgg caccagccca gcggagaata
     4321 aggcttgccg gaacgcttcc gttcaccacg gaaagttcgc cgagaccgga ttgggacagc
     4381 aggctcaaca gcgggatggt caccaggccc agcagcgtga cgaacgctgt caacgcagtg
     4441 catttcgcca agtacaggcg ctcgcggttc ggcgcggcca ccaggctggt ccgcagttgg
     4501 cccgacacgt actcactcga tgcggaaatg acgccgataa caatgattcc aatcagtccc
     4561 agcgcaaccc agtcgaagcc caccgtctcc ggactcgccc ctggggcaag tccggggtca
     4621 ttcgttcgga gcgcttcccc caccggaccc gcctgggacc acccgacgag gacgacgatg
     4681 agccacgtca gggcggcagt gatccacacg gaccttaaag tgacgagctt ggtgagttcg
     4741 gcgcggaaca gactgggcgt tcgggcagtg tcgacgagtg tcgtcatgcg gcgcttccct
     4801 tagctgcgtt gccggtccag tcaaagtagg cggcttccag gtcatggtga ccggctacca
     4861 gatcaacgac gtttccggac tggacgatgc ggccaccgga aatgacgacg atatggtcag
     4921 ctacgtgctg gacctcgtta atgagatggc tggagataag gacagtcttg ccgttggacg
     4981 cgagggttct cagaagcccc cggatccagc ggataccttc gggatccaag ccgttggtcg
     5041 gctcatcgag aacaataatg cgtggatcgc cgaggagggc cgcggcgatc cccagccgtt
     5101 gacccatccc caatgagtac gctcccacgc gtttccgggc ggcgtccgca agtccgacga
     5161 gctccaggac ttcaccgatc ctcgaatgcg ggatgccatt ggactgagcc agccaagtga
     5221 gatgggcctt ggctgtgcga cccttgtggg ctcctgagcc atcgaactga gctccaacgg
     5281 tccagagggg ggcgatgagg tcccggtaag gctttccttc gatgagcgcg gacccgctgt
     5341 ccgcccggtc gaggccgaga agcagacgga acgtggtcga cttgccagcc ccgttcgggc
     5401 cgagaaaggc ggtgactttc ccgggctcgg ccgtcagtga gacgtcgata attccgtccg
     5461 actgcccgta tttcttgctc aaattcttaa tctcgatcac tgtctgatct cctcggtagt
     5521 cgatgtcact tagcggcgaa ctggttggcg gcggaacaga acaagagcag cgaccaacgc
     5581 tgcgaccacc cacaccacga ggaccaatcc gcccgtcgca ggtcccaaat cgtccggcgc
     5641 ggaagggggc agttggtaga gctgggcgcc cgcctgatcc ggcaggaact tggccagggg
     5701 ggtgatgttc accatgtagg tggagacaat gagggccatc gccaagaccg tgcccatggc
     5761 cgccaatccg ctgcgaagga ccaccgacaa ggcgtaggtg aacagggcga tgagtatcca
     5821 gtaaaggacc acgccccata ggattcctga tgccgcttgt ggagttgctg ctatctggct
     5881 tgtttcggtg gtgcagtcga tgaccgcgca acgaatacct gccgacccga acacgctcag
     5941 gacggccgtg atgaatacgg cagcgacaat cacgatcgct ttggcagcca acacggcact
     6001 gcgctgcggg aggctgatca aggtgctacg aagcgagccg ctgtccgatt cctggtgcat
     6061 cgaccacgca gcaagaagga tgacccctat ttgtccatag tgaaggatga ccagaaaggc
     6121 cgtacctccc tcaaggccag ctgcctcctc cggcctccct gccttatggg cagcgtcgat
     6181 caggtttgtc agtatccagg aaagaaacac cgtgagcagc accgttcccg ccatggtgtt
     6241 gaggcaaaga cgcagcgtca ggagtttggt ggtctcggcc ctgacggcgc gggccatggt
     6301 ggttcgtaac cccggccgca cgtcgagggt cgctgtggaa gatgctggca tgactcaagt
     6361 caatccggac cggcatcgct tgtctgtctg caggtgttga cagtcgtggc acgttcctaa
     6421 acgggcgaag ggcccaccag gccgccttcg taggcgatga caacaagttg ggctctgtcc
     6481 cgcgcgtcca gtttcgtcag gattctactc acataggtcc gcaccgtggt tcgcgtgaga
     6541 aacagggcag ccgctatttc gttgttggag gcgccttgtc cgatgagggt caaggtttcg
     6601 cgttcgcgga ctgtcagttc gctgatgcgg tcgtgtgcgg ccgggctctg ggtgaagcgg
     6661 tctatgaggc ggcgggtgat ctccggggcg aggagggcgt taccttcatg tgcggtccgg
     6721 attgccttga ggatgtccgg cagcggcgca ttcttgagga gaaagccgga ggcgccctgt
     6781 cggagagctt ggtacacgta atcgtccata tcgaaggtgg tcagcatgac caaccgggtg
     6841 ctggatttcc gggaggccag aatgcctgca gcttcaaggc ctgtcatccg tggcattcga
     6901 acatccatga gggccacatc cggttgatgc tccaagatgg actccacggc ctccgcgccg
     6961 tccacagcca cggcggacac ggtcatgtcc ggctcgtcgt cgatcaagag gcgcagtgac
     7021 gtcctgatgt gagcatcgtc gtctgcgatg agcacactga tttcattcat cggctgtgcg
     7081 ccctccctgc agttcccggc agtgaaacag ccacacggta tccattggtc tcccgtcctg
     7141 cttcgaaggt cccgcccaat aactgagccc gttcacgcat gcctgtgagt ccgtgaccgt
     7201 tcttggaggc caaagccgcc cccgggccgt cgtcgaggac gctgatccgc aggtcgtcgc
     7261 cttcagtcct gatggtgatc cggcaggttc ctgctccgga atgccggatc acgttcgtca
     7321 gggcttcctg aatgattcga tacgcggtgg ttcgctgcgc ggccggaaga tcgtgggcac
     7381 tttcgtcggc gtcgatcacg acagatatac cggcccgtat ggccggctgc gacagctccc
     7441 gcaccagttc cggaaggctt cccggcggag cgtcatcagc cgtttcgcta cgttcctgtc
     7501 gcatcaacac ctgaagttgg cccaacgcat cacgggcgtc ggactcgatg ccctgcagtg
     7561 cagatcgcag atcgtcgggg gtggacgact ttacatgggc cacgacgccc gcccgcaccc
     7621 caatccctcc cagggtgtgg gacagtacgt cgtggatatc ccgtgcgagg cgaagccgtt
     7681 cctgcgcccg ggcattgcgc tcggtttcgc aacgcatgcg ttgggtgcga attcccaaaa
     7741 cccatgcggc cccgatgatg acggcgccca ggatgatgcc ccggatgctc gcttcggcgc
     7801 cctccgcaga gaccagaagc aaggacgcaa acagaagaat ttccagcacg atcagccatg
     7861 caggaaagag gcgtgtcccg aatcgttccg cggcaacgta caggcagagc cctgtcacca
     7921 ggaaaggatc ctcggtcatt cccaagctcc agccaacggc cgtcacaacg ccggtccaag
     7981 cggcagctag ccaaggaaac cttgaccgaa ggcagagtcc cagaacaaca aggcccccca
     8041 aagccagttg gaccagcctg cccggtgatt ccggcggaac cacggtgatc caaagccctg
     8101 ccaccacgat gatgccgacc aagccgttca gtagaacggg aatgatcgtt tcccggacta
     8161 cggagacgtg aacgttgtct ggatcagcgc tttgcgtcgt gctcgggtgt cgttggttca
     8221 taggccatct catttgtcag gaattggttc tgagcgagtt cccgataaag aggcgacgtc
     8281 tgcatcaatt ctgtgtgggt accgcttgcc acgaccttgc cttcatcgag caccaggatc
     8341 aagtcagagc tttgcacggt ggcgaggcgg tgggcaacga tgaccaaggt gcagcccgaa
     8401 gttacgtcgg cgatgagctc ccgcaccttt tcctcgctca ctccgtccag gttggaggtt
     8461 gattcgtcca ggagaagcat tgaagggttt gcgagcaagg ctcgggccac agcaattcgc
     8521 tgccgttctc ccccggagag gagcaccgct ccctcgccta cttccgcgtc gaggccaagt
     8581 tctgacctct gaaggacagc cgtgagattc agccgttcca gaatggccat catgtccttg
     8641 tcggatgcat ccggattccc tatgttcagg ttgtcccgga gggttccggc aacagcggga
     8701 gcgtcctgct ccacataggc aatgttggcc cggaccgccg accttgctac ttggtcaacg
     8761 tcggttccgc cgaacaggat ttgcccatcg gaagcatcgt agaagcgggc tataaggttc
     8821 aggatggtgc tcttgccggc gccggagggg ccgacgattg caacccgctg acgggattcg
     8881 atctggaatg agacatcgct caaagttgaa cgcagactgg gcccctccgt ctccccggaa
     8941 ggatggtcgt actcaaagct caccccacgg aaaaccaagc tggaatccct gatggtgggg
     9001 accacgttgc ccacaacgac gggcgcgtcc tgttcggtgg ggagctgcag gatctcgtta
     9061 atgcgcgcca cgcctccaag ggcctccccg atggcactca cggttccgaa gagctggccg
     9121 aggggcatga tgaggaggaa caggaagagt atgaaggaaa cgaggtccgc caccgtcaat
     9181 tcgcccgatg ccactctgag cccgccaacc ccgataacgg cgaggaaagt cacttgcatg
     9241 gcgatggagg aaatcgggga taccaaggct gtggtggccg caacacgcag tccaatggtc
     9301 cagacgccgt tcgcgtcttc cttaacgcgt tgggattcac gtgtacttgc gttggctgcg
     9361 cgcacagttc gtgtcgcccg gatggcgcgg tccattgagg acgagagttt ccccagggca
     9421 gtttgaaccc cgaggctggc gcgttcgatg taggaggtga cccaaacgac cgctgcgacc
     9481 gagaccaggg cggctcccag ggcaatgatc accagaaccg ggtccagaaa gagcattgcc
     9541 acgagcgcgc cgatgatggt gaaaacgcca gcgaaggact ccacaaagcc ctggctgagc
     9601 atgttccgga tcacggtggt gtcggtggtg acacgggcga cgagatcgcc tacacggcgc
     9661 tggtccaatg ttggtaccgg caggtgaagg atgtggtcga tgagattgtg gcgcgacctc
     9721 ctgatggccg tctcagcagt gcgctggatc aggtactgcc ggatgccacc aagaactcct
     9781 cccacaagga tgagcccacc cacaagccac ggcaagaggt ccaacggctt ggaagcactg
     9841 actcggtcga tcacttcacg gaccagcaaa ggttgcgcca aggaaagcgc ggatcccaga
     9901 aggctgagga gcacgatgag ggcaacgagc cggcgttgaa cggctacgtg gcggaacagt
     9961 tcggtcagcc cggcgcgtcg ggaagcattg gctgcggtct tcatttgtta ctcgcttctc
    10021 cgggctgggc cacggtgagg acggggacgt agctgcggat gcggtggggc tcatcgatcg
    10081 gcaacccatc cacttcaatc catgcatggg cggcgaaggg ctcaagttgg taccccgttt
    10141 tccatcccgg agagtgacct tccatccggc acagcatgaa ggctgcgatc gaccgctgca
    10201 ggcacccctc gccggcgcag cgggcgctga cggcacatac agctgcccgc atgaggcgcg
    10261 cttggtgggc gttggtggaa cggtgtgaat gtgaaaggcc atggagaact gactggagca
    10321 gcgccggtgg cagcaaggtc atgacccagg cgacgccgac taccgcgtga gtccgcaatc
    10381 ggaacagccc ctgtggcatg acggtcggct gcgggctgat gggaagactc atgagctggc
    10441 cctccgaatg attcctgact gctggagctc gtcaatcaaa gcgtgtacgt cttgacgcac
    10501 gcggtggtgg tcaactccgt aggattcaga aattctgtca acgacggcac cgacgttgag
    10561 attttgctcg attccggcca tgacgtccgc tgctgtggca tttccacgcc agtaggtgcc
    10621 gcctcgggcg tcgaacaccg ttaccccgtc atcatctacg ttgaaggtaa ttttcggtga
    10681 aggccggaat acgtctccag cctcgacggt gcgggttgtc ttcttcctca ttgaatggcc
    10741 ctaacccatc tctcgacgcc ggcgagttgt tcgatttcaa agagctcgtc cgtgctgacg
    10801 accggcatgc tcaaagcatc gcgtacagcg tcagcgttga tatggcccat gtccaccaga
    10861 tagctttcgt cgaaaaggcg ggacagatcg tgccggcgct tcttgtactc ggtgaacagg
    10921 tcggagctgt attcaccctt gtcttcgcgg gtgaacagcc aacggggggc aacaggctcc
    10981 gtcgcccgcg ccaggagcgg tttgctatcg cgggttccaa cgaggatgtc agtaggcagg
    11041 ctcagaatga gacggactac cgcatcgtcc aagaagggcg cctcccaagc gacgccgagg
    11101 tgttcgtagg catggcccac ttgccgcaca acttcgcctt ggaacatgac tgcctcggtc
    11161 atctgatgcc tgaagcgatc cttatggtgc gggcgggctc cctgtgtgag cgcatccttc
    11221 actttttgcg ccactacttc ccgggtttct gctgtggcga atttagaaat gccgaagccg
    11281 ggcgcccatg agaaggcctc ggccggcccc acgatgttcc ccgcccgggc ttcaatacgc
    11341 cgtagcatct cagtttcaaa gttgacgttg gatcccaccg cgcgggctac tgccagcgtg
    11401 gaccaccgct gcattttgcc taaccgccga atgatccgca gaccggccct ccacgatgaa
    11461 gtcgtgagga gatccagggc ggttgtggga agtggatcaa acaattcgtc gccaccaacg
    11521 cccgtcaggt gagccttgac gccacgccgg gaggcatctg tgagcaaaaa tccgaggtgc
    11581 ttggaattcc cggcccatgc cagcggaccg tcatcgaggc tccggatgtt ctggtcgaat
    11641 tcgctgaacg cgcctgatgt ggcggtcagt gactccagct cagtgaattg cccgcgtagt
    11701 tccgatgctg ctcgacgcgc gtactggcta tcccggttat ggggatcgtc cgtacccgca
    11761 tggtagtaaa tgctctcttc ctgaagtgaa tccagaatgt aggccaggct ggttgaatcc
    11821 atgccgccgg acacatcagc gctcaatttc ccgtaggaca ggatgcggcg ttccatggac
    11881 cgtgtcagtt cagccagcag cagttcagcc gcctcggaaa gatccagctt ggggtgctcc
    11941 gtcgcaatcg cctgatccag caccttggga cgcccatcgt ggtaggtgag cgtggaacct
    12001 ggtttaactg cattgattcc ttcccagaac ggaagatggc gtaggaagcc gggcaaattt
    12061 gtgcacaggg caagccggac cctgctgtca tcgagcttgc tgtgggcaat gcgtcgcagt
    12121 gctccctgcg acatcgaggc aaccggtgtt ccgtcgatgt cggtccagta cagtgtctcc
    12181 gcggttgaga ttgatccggt gatgtcgcga gcgtagcccg ggattgcgcc tggggcggca
    12241 cgcaaatgtt ggtgggagac gacagaatcc cgcatttgcc gctcactgag cctggaatcg
    12301 aggatcgtga cagcggcgct ggacagcgac gccgaggatt cgtcgatcaa tcccgaggcg
    12361 ctgcccctgt tggctaagaa gagttgcggc attgtgtcct gacacctgac gtgtaatgga
    12421 gcgaatggaa agcctgatgc agaacgggag cctcgtcgcg atgacgaggc tcccgctcgt
    12481 acctctgtac tgctatcagc cgacgtcgac cttaacgaat gcccgaccgc cgaagatgtc
    12541 gcgccagcgt ccgaaccaaa caccgtttgt cacttcacgg aacgaaccca cccgcgctac
    12601 acgcggagca gaatagttgc ttttcatcat catccctcct ccctaggtga taattacacg
    12661 gctactttgc cggttgtaac tcgagtatca cttctggttg agaacgtgac aagagccatc
    12721 aaggggtttc ttaaagttgt tttagtttct aatttcctta tgccatactg gcgatgcgga
    12781 tgctgttctt caggccaggt caggatcgct ggcgcgcttc ccgaaagtca ttatcgatca
    12841 cttgtgaacg cagtaagcct gccgggccca tccgccggtc tctatctgtc aaaactcaat
    12901 tcgatattca aatagtttca actcaaaaat gggggttttt gggaaattgg ataggcgcaa
    12961 tatttctatt ggttacgcca gggaaagcac gcttggtccg tcgctggcgg atcaggttcg
    13021 aatgctcaag gcagccggag ctgtggatgt ctatgaggag cgtgcaaccg gagctaccga
    13081 gctgagggag caatgggggg cctgttacaa ggtgctccag ccgggggact cgctgcttgt
    13141 gagtgacctg accaggctgg ggcggagtac ctcagacttg gcgggcatca tggcgctgct
    13201 ggcccagcgg agcgtgagct tccgtgtagt gggagaacct tggttggata ccgatggcca
    13261 gtacggccct gtcattctca agctattcga gtccatcgcg aactatgaac gcagcaggtt
    13321 gtcggagcga acaactgtgg ggctcgcagc cgcacgtgcg cgtgggcgcc ttggcggccg
    13381 acctccggcg atgaccccac acaagcttga gacggcgcgc aaccttagaa gcaagaagct
    13441 gaccctcagt gaaattgcgg ataccttggg ggtcagcacg tcgacggtag caagagccct
    13501 gagtggtcct ctgtaagccg ctgcggatcg gcggtatcag taccccagct gctcgcacaa
    13561 cgacgcgagc tgatgaattg atgacggtgc gtcgatgttt atgccggtca ctgtgtacgg
    13621 ctatccagcg ggtgtcgcct cttaggcggg gctacgccgg cagggtactg aaagcgccgg
    13681 gacaaggcct acgagcaggc gttgtcccgg tcctgcgacg gcatgaagac tcaagtcacc
    13741 gactcagcca gcgggtgccg ttcccttgtt cagaggcgat tttgttcagg ggcgaatccc
    13801 gggcgcctcg cttgctaccg cctacttccc tttcttcccg ccccgcttgg ccgcagcgtt
    13861 catcgccgac ttcaccgctg gcggcagccc cgccgtctcg gtttccggct cagcgacggt
    13921 cccgcgccag cgagccagtc ccttcatgcc gtggtagatc accagcgcag cagcggagcc
    13981 aagggcaatg cccgtgaact tcagctcacc gatggtccag gtgtagtccg cgatgccgat
    14041 gatcaaggcc acagcagcgg tggtgaggtt gatcgggttg gagaagttga ccttgttctg
    14101 aacccagatc ttcacgccaa gcacgccgat catgccgtag agcatggtcg cggcaccgcc
    14161 caggacaccc ggcgggacgg tcgcgatcag ttcgccgaat ttcggggaga agctcagcag
    14221 gatggcgaag acgccggcca cccagtaggc cgccgtcgaa tagaccttgg tggccgccat
    14281 gacgccgatg ttctccgcgt acgtcgtggt accggaaccg ccgccgaacc cggcaagtac
    14341 cgtcgcggcg ccgtcggcca tcagcgcgcg gccggagacg ccgtcgaggt tctggcccgt
    14401 catggcggct accgacttca cgtgccccac gttctcagcc accagcacca gcaccaccgg
    14461 cacaaacaga cccactacgc cgatgtggaa ttcgggcgtc tggaaaaacg gcaagccaac
    14521 ccaggctgcg gcatccatct tttcgtagct gacctcgccg cgcatcatcg ccacgaggta
    14581 gccgacaacg acgcccacca gaatgctcag gcgcccaagg atgcctcgga acagtacaga
    14641 aaccaggatg atcgtcacca gcgtgatgag cgcggtgacg ggcgcgaggt cgaagttcgc
    14701 cttcgccgcc ggagccaggt tcaggccgat cagcgcgaca atggcgccgg tgacgatcgg
    14761 cggcatgagc cggttgatcc attcggcgcc gaacttctgg accaccgcac caataagcgc
    14821 cagtacgacg ccggcaagca ccacgccgcc caaggcgccg ccaacgccgt actgctgctg
    14881 ggacgccatg atcggggcga tgaacgcgaa gctcgatccc aggtagctgg gcactcgccc
    14941 cttggtgatc accaggaaca gcagtgttcc gataccggaa aagaacagcg tggtggccgg
    15001 cggcatgccc gtgatgatcg ggaccaggaa agtcgcgccg aacatggcaa ccacgtgctg
    15061 catgccgatg ccgatggtca ggggccaggc gagccgctca tcgggtgcca ccacgtgacc
    15121 ggggcggatg gacttgccat taccgtggag cttccatttg gtgccgagca tgctcatggc
    15181 ggagccttcc tcagaagagt attgggattc ggtgcaacat taccgccaaa gtacccgcgc
    15241 cgccccgcta aagctgctta ccgtggaacc agcttgaaga ggaacttcgt tttcaccatg
    15301 acccacagaa tggcgagtaa agctgcgtac acggccgagt tcagccagag gttgccgtcc
    15361 cgcagcgccg ggatgttggc gatagccacg atgaagaaca cgtgcatgat gaacacgtac
    15421 agggtggctt ggccaagagg tatgaagaac cagccaacag cgcgtgagag cggcttccag
    15481 aacgcactca ggagggcata aagggcgatg gttatgacga ggacattcac aacacggccc
    15541 gggcccagat aagtgcggcc gaagaaggtg tcgtagaggt acctgaacgt ggtctccggg
    15601 atgagggcaa ggcgcacatc caactggttt gtcagatagg gtccgctcca cgagaaaagc
    15661 gcgcaggctg cggccaggaa aacgcacacg cccagaagaa tccgctgacg gggatgggcg
    15721 aaccagtcga tgattcgttg gcggtggaac cccgcagtca tgccgaggac gaacagcaac
    15781 tgccatacga gcaggggaaa ggagtcctcg aactgcgagg gaagcaaccg gaaccggaac
    15841 acggatccac cgatgtagag cgccagactg accgtaagca ccggccaggt gagtccgcgg
    15901 gacagtgcca ccaggatcaa agggctgatc aacaacagga tgacgtagag gcccatgatg
    15961 ttgaactgcc acggaccgac ctgcaacaac agcagggccg gaatcaggcc ttgcgggacc
    16021 ggaaactgca gcaaaccttc catcccggcg tagaggtcat aggtcgttcc ggcggctgaa
    16081 tgcccggctg cgcctgtgcc ttgatcggtg aaggtggtga cggcagcggc gttaatgaag
    16141 gggagcaggc tcagaccgta gacaatcagg accacggcca gggcggtgaa gtagagcttc
    16201 cacgcccgtt tggttgtccc gtccaccacg tcccccagct ccgtggagat gcgcggcccg
    16261 tagaccatgc ccagcaccac cccggagagc atgacaaaga gttccgcccc ggagaccact
    16321 ccgatggtct cctggctcag cagttggaaa accgagttga tgcccacgtg gttgaccacc
    16381 acgaagacga tcgccagtcc gcggagcatg tcgatcctgg catcccgcct gccggaaccc
    16441 gtgtacgacc acttgttggg ggccgcccgc gatgacagaa gccagagtgc cgcgacggcc
    16501 acgaggaccg ttccggcggt ggcccatgca gcccatccac ggatcacagt gtcggacttc
    16561 gcttgcggga tctcaagacc cggaacgtcc ttcagcccct tctcggtgac aggaccgact
    16621 cttaggccgg aggtgtccaa agaggttcgg aatggagcgg ccagcaacgg ttgggcggtg
    16681 gcgcgccagt caatggacac cttgctctga tcgcgtgcat cggtggtttc gttccagacc
    16741 actgcccgga cggacccatt ctcgggctgg gccaccgacg cgaagacctg gtgccaccac
    16801 gtctgcttga cgtcaatctc tgcggcgccg ccggctcctg gcgagtagaa agccccggtt
    16861 tcgatcagca gcggcttgtt ccgggcttgt gcataggtgc cataaaaatt gtccgttccg
    16921 gtgccaccac tggacgcgtg cagggaatcg ttgaactcgt cggccgcagg gagggtgttc
    16981 tgggcggagc ctgcaccggt ggtgtcgtga taaatggaca ggcctatcca gtccacaacg
    17041 tcatcgcccg ggtaataggg gtcaaacgcg gagtcgtcga ggtcccagac gccgttagcg
    17101 ttggtgtcca gcgaggccaa ggggacgcct ttgggtggcg tggacgtggc cgtctggaac
    17161 gggtagtcct tctccgctgt cggcgaccac accatcacgg gatctgccag gctgctcttg
    17221 agcgcggcag caacccggcc aaatgctgcc cggtatgctt cgggttcctg gccccaagcc
    17281 acccatgggg cgttcatttc cggtgcgaag cggacgaaga ccttgcccct gaagccggca
    17341 gccgccgtcg tgatttgacg tgcaaaagtg gccgcggcgt cgtcgctgac gtcccggagg
    17401 gatattccgg gacgtacggt gagcagcgcg tgggagcctt ggccggctac ctgggagaag
    17461 taatccctga ggtaatccag accgccttcg tccatgggca tggatacgtt ctgtccgtac
    17521 agggcagctg gctcgccgag gcgctgggcg tagtccgcag ctgagtcctt gtcccagtcg
    17581 agcaaagttc cgaagtagcg ctgaccggga tcgtcgccgt cggccggttg ccggtccaag
    17641 gcccaagctt gcgtggaggg gagcaggaac gccagaagca gcaggacaag tactgccagg
    17701 gcccgtcgag gggccgccag gggaaaggta ggcatcaggc cccttctggt gtcgtcattc
    17761 ccacagttga gacgccaacc cacacggacg ccggctcgta aaaacgatgc tacccatttt
    17821 cccgctgtgc ccaacgtcac gggccgtcat gggaagagga cagcggaagt tgaagttgca
    17881 accatggaaa gcagaagtgc ccggccagcc cagggtcagg gcccagcgaa aggttcacaa
    17941 atgacgattg cccacgaaga agcagtcatt gacgccgcag cagtcgacgc catttttgcc
    18001 gaagcccgta ccgccaacag cttctccggt gaggtcaccg aggagcaggc ccgcgccatc
    18061 tacgagctca ccaagttcgg ccccaccgcc ttcaactccc agccgctccg cgtgacgtac
    18121 gtccgctccg acgaagcccg ggccaagctg gtagaccacc tgtcccgcgg caaccaggcc
    18181 aagaccgcct cagctccgct ggtcgccatc ctgtcttacg acaccgactg gcagggacag
    18241 tgggacaagt tcctccccga gtacggcgcc cccaaggcaa tgtatgacgc cgatcccgcc
    18301 ttcgctgcct ccaccggcaa caacaacgcc cacctccagg ccggctactt catcctggcc
    18361 gtgcgctccc tcggtttcgc cgctggcccg atgaccggcg ctgacttcgc cgccatcgac
    18421 gccgagttct tcccggccgg cgaccagaag agcttcctcg tggtcaacat cggacagccc
    18481 ggcccggacg cctggggcga agccaagccg aagttcgctt acgacgatgt cgtccgcacc
    18541 gtctagtcat cccggggccg tcgtccagga cacccataac gcctgatgac gcagaaacgg
    18601 attgaggaca cccaaattca ggtgtcctca atccgtttgg gtgtcgctag ctgttttgcg
    18661 cggcgttggt accaccagat gccgccgcaa gcgccccctg aatcccctgg accaggccag
    18721 ctgcctgttg cgatatccag gtgcccggtt cctccgagcg ggcgggccag cgtttgccga
    18781 tgaagttcat cggatgcacc acaatgttgc cggtctggtg gtgcactgtg gcttccgtta
    18841 cgccgtccgg gtaggtgccc agaacccacc gaagcccggg gacctccctg atgaggtgat
    18901 ctccaagagc tgcgcccatg atgttgatca tcgcgttggg atcgaaatcg ggctcatcct
    18961 cgacatggtt gacagtcatc tgccacaggg cgtcgatgta ctcgagatca gtgcgtggat
    19021 gatcgctccc agggccgtcc accgccgaac ccacttgctg gaatgaacgg agaagatcct
    19081 gaatccactc ttcctccgct ggggacatct cctcgatcag cggccccgac actacgcgat
    19141 gaccccgtcc accagcgcct tggcctcttc ctgaacttgc tttaggtggt ctgcgccctt
    19201 gaacgactcg gcatagatct tgtagacgtc ctcggtgccg gaggggcggg ccgcgaacca
    19261 ggcgttctcg gtgacgacct tcagaccacc gatcgaagcg ccgttgccgg gagcctcggt
    19321 gagcttggca gtgatctctt cgccggcaag ggaggtggca gtgacgtcgg cagcggagag
    19381 cttgcccagc ttggccttct gctcacgcgt ggcggcagcg tctatgcggg cgtagacagg
    19441 cgcgccgaac tggtcggtga ggcccttgta caactgcgac ggcgacttgc ccgtcacagc
    19501 ggtgatctcc gacgccagca aggccagcag gattccgtcc ttgtccgtgg tccacacgct
    19561 gccatcaagc ttgttgaagg aggcgccggc agattcttcg cctccgaatg ccccttcgcc
    19621 ggacaggagg cccgggacga accacttgaa gccgaccgga acttcgacca gcttgcggcc
    19681 gagtccggcg gcaacgcggt cgatgatcga ggaagacacc agcgtcttgc cgactactga
    19741 gtccgggttc cagccgctgc ggttgcggta caggtagtcg atggcgacgg cgaggtagtg
    19801 gttcgggttc atcagcccac cgtcgggcgt cacgatcccg tggcggtcgg cgtcggcgtc
    19861 gttacccgtg gcaatgtcga acgctgagcc cgcgcccgag gagccggtgg aatcggacat
    19921 ccgcttgatc agcgacgcca tggccgacgg cgatgagcag tccatgcgga tcttctcgtc
    19981 ccagtcgagg gtcatgaagg cccactgcgg gtccacggtg gggttcacca cggtcaggtt
    20041 gagctggtgg cgctcgccga tctcgcccca gtagtccacg gaagctccac ccatggggtc
    20101 ggcgccgatg cggacgccgg cctcgcggat ggcgtcgagg ttcagcaccg acgggaggtc
    20161 gtcgacgtag ctgctgagga agtcgaactt gccggtggtg tcagcagcca gggcatcgtt
    20221 gagcggcatg cgcttgacgc cgcggagccc gttctcgagc aactggttgg cgcggtcggc
    20281 gatccagcca gtggcgtcgg tgtcggccgg gccaccgtgc ggggggttgt acttgaagcc
    20341 accgtcgccc ggcgggttgt ggctgggggt aaccacgatg ccatcggcct ggggtgtgcc
    20401 cggcgcagct tcacggttgt acttgaggat cgcgtggctc agggccggag tgggtgtgta
    20461 tccgtggcgg gcatccacca gaacggtcac accattggcg gccagcacct ccaacgcgga
    20521 gttctgcgcc ggctcgctca aggcatgcgt gtcgcggcca atgaacagcg gcccggtgat
    20581 gccctgacgg ccacggtact caacgattgc ctgtgtgatg gcaaggatat gcggctcatt
    20641 gaacgacgcc ttcaagctgg aaccgcggtg ccccgaagtt ccaaacgcca cgcgctgcgc
    20701 gggatcgccc aagtccggag ctacgtcgaa atacgcgtcc agcagggctg tgatgtcaac
    20761 aaggtcctgg ggaagggcaa ctgtgcccgc tcggctagcc atggggtcca gcatgccaga
    20821 ccgagggccc cgctgacacg aaatgtccgt gatccggccc ctgtgacgcc gaatggcgga
    20881 cttcttcgga cgatatctcc cggtatcgcc aaaggttcac tccgcgttta ccataagtga
    20941 ccttagtgcc ggccttccgc caagacagcc ggccgccaca atgcgcgcta ccttatatgc
    21001 ggccccggac ggcggtagtg ttgggatcaa agaccacatt cagggggatt cctatgtcag
    21061 atcagccatc caagggtaac gaggataagc cggccggcta cgagccgccg cagtacgttc
    21121 ctccggcgca gttcagcgct cccgagcaga acccgccggc cccgggcgct cccgtgccgc
    21181 cggccccggg cgctcccgtg ccgccggccc cgggcgctcc cgtcccgccg gcgttcgagc
    21241 cgccagccca gtcgttcgac cagggcaacg ccacccagcc gctgccgccg tatgagcaga
    21301 acgcttacgg ccagcagaac acttacggcc agcagaacac ctacggccag ccgggcaacc
    21361 aggacgccta caccccgggc gactacagcc agcagcctgc ctcgccgtac ggccagccgc
    21421 cgagcccgta ccagcagcag gctttcggcc agcagcccta cggccagccg cagtctccgt
    21481 atggccagcc cgcctactac gcaacgccca cccagcccaa gggcctgagc atcgccagca
    21541 tggtgtgcgg tatcgccgtc tacatcggct tcggattctt catcctcccg cagatcgctg
    21601 ccgtgatcct gggccacctc gcacttaagc gtgaacctgc aggcaagggc atggcgatcg
    21661 ccggtttggt gatgggttac ctcggaatcg cgctgacggt ggtgttcggc atcatcttct
    21721 tcgccgccat cggtgcctcc accaacaggt acaactacta aacaaaaacg ttcgacggcg
    21781 ccccttgcgt caggtgggaa tcccgcctga cgcaaggggc gccgtcgttg gttaacgcag
    21841 gctacgccac ccaaattcgc cggggacaga gaaacggacc aacgctgccc ggatgtgggc
    21901 ggcgctggtc cgtttgcgtg tcgctgggca aagtcttagc gaacgccgcc catcaacttc
    21961 ttgattgccg gcgatgccgc ggcaagtcca acggccagga ccactgccac gccgccgatg
    22021 cccaggaagt aggggagctc gtcgtcgggg ttgtacagcc ccgcgaggat gcctgccaag
    22081 gtggttccga gcgagaccga caggaagaac agtgccacca tctgggtgtg gaatgcctgc
    22141 ggggcgagct tggtgctcac ggacaggccg atgggagaca ggaacaactc ggccagggtg
    22201 aacaggaaca ggatccccac cagggccagc agcggggtct tgccttctcc ggccagcggg
    22261 atgaacgcca ggaacgccag gcccatgatg agcaggcccg cggagaactt caacggtgaa
    22321 ctcggttgcc tggagccaag cttcgtccac agggcagcca tcacaccggc aaagatgatg
    22381 atgaagacgg gg
//
