LOCUS       NZ_JADBDR010000019     23535 bp    DNA     linear   CON 15-NOV-2023
DEFINITION  Paenibacillus sp. OAS669 Ga0395962_19, whole genome shotgun
            sequence.
ACCESSION   NZ_JADBDR010000019
VERSION     NZ_JADBDR010000019.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus sp. OAS669
  ORGANISM  Paenibacillus sp. OAS669
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 155773)
  AUTHORS   Northen,T.
  TITLE     Enriched cells from switchgrass and soil in EcoFAB chamber, Walnut
            Creek, California, United States
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 155773)
  AUTHORS   Northen,T., Huntemann,M., Clum,A., Wang,J., Palaniappan,K.,
            Ritter,S., Chen,I.-M., Stamatis,D., Reddy,T., O'Malley,R., Daum,C.,
            Pennacchio,C., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-OCT-2020) Prokaryote Super Program, DOE Joint Genome
            Institute, 1 Cyclotron Road, Mail Stop: 91R0183, Berkeley, CA 94720,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 196.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/15/2023 05:10:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,886
            CDSs (total)                      :: 6,766
            Genes (coding)                    :: 6,693
            CDSs (with protein)               :: 6,693
            Genes (RNA)                       :: 120
            rRNAs                             :: 11, 8, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 9, 8, 4 (5S, 16S, 23S)
            tRNAs                             :: 92
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 27 of 73
            Pseudo Genes (incomplete)         :: 56 of 73
            Pseudo Genes (internal stop)      :: 13 of 73
            Pseudo Genes (multiple problems)  :: 21 of 73
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:30:42
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 112470
            Orig. end                         :: 136005
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JADBDR010000019.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23535
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23535
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23535
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13535](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13535)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            113..1621
                     /locus_tag="GGC63_RS30370"
                     /old_locus_tag="GGC63_006275"
     CDS             113..1621
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010272838.1"
                     /locus_tag="GGC63_RS30370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GGC63_006275"
                     /product="sodium:solute symporter family protein"
                     /protein_id="WP_192705472.1"
                     /transl_table=11
                     /translation="MSMLDWIVLGLFFLLMVGIGVWSFRQISGTQDFFAAGGKMPWWLS
                     GISHHMSGYSAAVFVAYAGVAYTYGFTLYVWWAIPVSIAVFAGAALIAPRWARLRQRMN
                     IESPMEYLSTRYNVPTQQLMAWSGVLLKLFDVGAKWAAIAVILNVFAGVPLNLGIFLSG
                     LISLIYSAIGGLWADAWTDFAQFIVQLIAGIAMFVIVVMKLGGMEAITDIWDKLPPSHS
                     QPLVGPYTLGFVLAYVLIDFLSYNGGTWNLAQRYIASPNGSEARKAALLSGVLYLVWPL
                     ILFFPMWAAPLFYQNLKDPTQSYSMMTMDLLPHGLIGLVLASMFAHTMAMTTSDANAIT
                     AVITRDILPVMSKRYRSLSEKAALRVARGAMITFVVLTLIIAVYSSTFGGILNLLIVWF
                     GALVGPISIPMLLGLIPAFKRSDSTAAIVSWAAGIVTFVIVKYVITVSTATLVASPVVV
                     SAILFIGMGWLKGSAPVAPKVEELLQSLSADAKEANSPDHGMKA"
     gene            1700..2983
                     /locus_tag="GGC63_RS30375"
                     /old_locus_tag="GGC63_006276"
     CDS             1700..2983
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019004733.1"
                     /locus_tag="GGC63_RS30375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GGC63_006276"
                     /product="AGE family epimerase/isomerase"
                     /protein_id="WP_192705473.1"
                     /transl_table=11
                     /translation="MNSIMNEAWDPRTLLSFYKRHLLEDLLPFWKHAVDQRHGGLFTCF
                     TNSGSDLVNTDKYTWSQGRFLWIWSRIARLTDQGVLPGEASTFQQEAEHAAAFLKNHVV
                     LSNGNCAFLLTEDGRMKESVPGEGFDTSFYADCFVVLGFAELSRCSGRQELANDALERY
                     DRIRLRLRDGQIRSEPYPIPQGLKSHSVTMIMLNISEQLMEALQHFRHPAYERLKKDCL
                     HYAESIITEFRMPDQRIAELLPVSGETPPTVLCRHVNPGHTLECMWFVIQTARQLGRED
                     LITQTLPVIRKAFELGWDTEQGGLLRFVDQDGGPPTGQRTGDPYEALILDTWDTKLWWP
                     HSEALYASLLAYELSGDPGFKELYRQTHDYVFRTFPHTDPRIGEWIQIRDRSGEPMDKV
                     VALPVKDPFHIIRNVLLIIELYSDASSA"
     gene            2995..4290
                     /locus_tag="GGC63_RS30380"
                     /old_locus_tag="GGC63_006277"
     CDS             2995..4290
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016612.3"
                     /locus_tag="GGC63_RS30380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GGC63_006277"
                     /product="neutral/alkaline non-lysosomal ceramidase
                     N-terminal domain-containing protein"
                     /protein_id="WP_192705474.1"
                     /transl_table=11
                     /translation="MTRSLHLGTAKVDITPAMPVPLAGFAHRTGTFEHIAQPLYARIHC
                     LQQSRVSGSKTTVLLVSADLIWWGSDLVNRLSPKLRERYGLDSVLLHATHNHSGPQTSG
                     CFTDALGRPDPGYLQELERRLESGIEQALQTMEPVMMEKGTGHCRIGFNRRKDIDGHIE
                     MAPNENGPVDPEVTVIRFRTPDGRTKGLFVHYTCHPTTTGDSEISPEYCGAALERIEQA
                     LGSGVTGAFLQGCCGDIRPALVQDGQFYRGHRMEVERFGSWLCEEALRICCQPMNELAP
                     ALLPSHTLVLPLPFQSVPTVEELEEQAKLADIQGERARLLLGQPTRRQGSIPLEITRLT
                     LAKELSLITFNAEMVVDYGLFVKKASRGTMLPLGYTNGMIGYVPTAEQLEQGGYESHGS
                     VPYFGLQAPFQPQIESLIRNALAQEIREEIEP"
     misc_feature    3026..3044
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 22.72"
                     /tool="antismash"
     gene            4287..5066
                     /locus_tag="GGC63_RS30385"
                     /old_locus_tag="GGC63_006278"
     CDS             4287..5066
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010272187.1"
                     /locus_tag="GGC63_RS30385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GGC63_006278"
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="WP_192705475.1"
                     /transl_table=11
                     /translation="MNETIHPLRTQTVDRLQVHVYENREQLGKAAGSDVAAKMKELLGS
                     KSSIRMIFAAAPSQNEFLQTLKQADGIDWSRVTVFHMDEYIGLAPEAPQRFSAFLRERL
                     FDEVKPGNVHLINCSGDINEECQRYAGLLGDAPIDIVCLGIGENGHIAFNDPPVADFND
                     PALVKSVELDLPCRQQQVNDGCFASLQDVPTHALTLTIPALFSGAHLYCMVPGVTKTAA
                     VQRTLRGPISTECPSTILRRHSDCTLYLDKDAYGDLG"
     gene            5079..6269
                     /locus_tag="GGC63_RS30390"
                     /old_locus_tag="GGC63_006279"
     CDS             5079..6269
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019004744.1"
                     /locus_tag="GGC63_RS30390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GGC63_006279"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_192705476.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 4.9e-12, bitscore:
                     39.0, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGNVTTVEGIHYRTKEPVTVHIERGRISAIQPLSTKKKAALPWI
                     APGLVDLQINGYCGSDFNTIPIAAGAVQRATRGLWKEGVTSYYPTVITNGDAEIEQAMQ
                     SIARACDEDPAAHAGVAGIHLEGPFISPEDGPRGAHDSLYTKAPSWPLFQRWQEAARGR
                     IKIITLSPEWPGSVEFIERCVEQGVTVSIGHTSASPGQIDAAVKAGARMSTHLGNGAHL
                     MLPRHPNYIWEQLSQDGLTACLIADGFHLPESVLKVILRTKGERALLVSDAVYLSGMEP
                     GVYDNHIGGRVVLTPEGRLHLADNPGLLAGSVQLLPWGISHLARSGMAALEEAWDMASI
                     RPAAFMQLPSQNGLSVGSPADLALFEWNRQSLSIVQTYKNGNRVFDSTTSSREGSL"
     gene            6266..7024
                     /locus_tag="GGC63_RS30395"
                     /old_locus_tag="GGC63_006280"
     CDS             6266..7024
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SIS_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF002805.0"
                     /locus_tag="GGC63_RS30395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GGC63_006280"
                     /product="SIS domain-containing protein"
                     /protein_id="WP_192705477.1"
                     /sec_met_domain="SIS_2 (E-value: 3.9e-40, bitscore: 130.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAAMTQYLHKIIQHLELLHQEEQASIARAARMMAEHIKQDKLV
                     YAYGPGGHSNLGSQEIFFRAGGLMHISAILDEGTLLSGGALRSMAVERTPGYANIVLDD
                     YGLKQGDLLIIINSYGINSATIDSALEAKARGIRTIGVTSVRHALATPADHVARHPSKH
                     NLHDLVDIVLDTKIEVGDAVVEIEGLDQRVAAMSTFANAYLLNSLVAETIELLVKDGIR
                     PPIWMSGNASGGDESNSRFIQQFKGRIKKL"
     gene            7212..7628
                     /locus_tag="GGC63_RS30400"
                     /old_locus_tag="GGC63_006281"
     CDS             7212..7628
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013915072.1"
                     /locus_tag="GGC63_RS30400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GGC63_006281"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_192705478.1"
                     /transl_table=11
                     /translation="MQGYNVLMIYNHSMDRLLMCKRLKNPYKGLSNLVGGKIETGEAGF
                     EAAYRELLEETGISQEDVTLHHVMDFTYYLQQCYVEVYAGRLKHDIAVTGDENELYWSD
                     LDQDFFDMSQYAGEGNIGHMIEQVNMYKEILLTD"
     gene            complement(7625..8008)
                     /locus_tag="GGC63_RS30405"
                     /old_locus_tag="GGC63_006282"
     CDS             complement(7625..8008)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024905.3"
                     /locus_tag="GGC63_RS30405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GGC63_006282"
                     /product="FUSC family protein"
                     /protein_id="WP_264082129.1"
                     /transl_table=11
                     /translation="MTERKADPVPVKTIQRVTGTVIGVAAVSALFAYTLPEWAVVVAVG
                     LLAGLRPWLKARNYLLYSATMTPLIFLLYSATMTPLIFLLMDAGKPLDGLALLDRITAT
                     LIGAGLVVLLNLIFTRPVFQERN"
     gene            complement(8332..8799)
                     /locus_tag="GGC63_RS30410"
                     /old_locus_tag="GGC63_006283"
     CDS             complement(8332..8799)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010493230.1"
                     /locus_tag="GGC63_RS30410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GGC63_006283"
                     /product="SRPBCC family protein"
                     /protein_id="WP_192705479.1"
                     /transl_table=11
                     /translation="MAAWKNQAPVAKAEMLIRRPVEEVFEAFIDPAVTTKFWFTHSSGR
                     LEPGARVKWEWDMYGASAEVEVLEIEKNQRILIHFGSRVEWIFTSKGEKETFVTITNIG
                     FQGEADDVVKQAIGSTEGFTIVLCGLKALLEHGIVLNLVSDKAPYAHVKRG"
     gene            complement(9004..9762)
                     /locus_tag="GGC63_RS30415"
                     /old_locus_tag="GGC63_006284"
     CDS             complement(9004..9762)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019450.3"
                     /locus_tag="GGC63_RS30415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GGC63_006284"
                     /product="copper amine oxidase N-terminal domain-containing
                     protein"
                     /protein_id="WP_192705480.1"
                     /transl_table=11
                     /translation="MKKIILPLSIGVMIGLTATTVSAASESVQAAIAQFVFKVNGEEKE
                     LKNSPLVVDGTSYLPVREVAALLGYELDYDEATRTIQLDPKKANHSMYQELTAAPDLTE
                     WIKVPDLLRFYEGNDIKASLSGDSSTTHLKIGVYGVGFPFAFSDQYQQPDVPKLYQRPS
                     GKLSMLVYQSNLFVNKSEIKNLGYPIEEEWIPAAEIANDQVKLDFTPLNGVKKLQPEFL
                     NTEQGILRAMNSKDGVLLNKEDLRARGFIK"
     gene            complement(10001..11572)
                     /locus_tag="GGC63_RS30420"
                     /old_locus_tag="GGC63_006285"
     CDS             complement(10001..11572)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004436719.1"
                     /locus_tag="GGC63_RS30420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GGC63_006285"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_192705481.1"
                     /sec_met_domain="PF00881 (E-value: 3.7e-10, bitscore: 33.5,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLDRFLHSLHTANDESRPPDWEVDWEDAPLTYKLYRGLPVVPLS
                     AEMPLSLTDRPTRTFPDLLSLGHLLWYAYGLTRVSQFPADVTMYGGTQVPMYRRFVPSG
                     GGLYPNELYVYWKTSDVPEGIYHYDAAHHRLVRLREGNYDAYLTRALGGQCEMEGCCGA
                     VMVSVMFWKNFYKYHNFAYRLQGLDTGVLIGQLREAARQFGYDSAMCYQFLDRGVNHLL
                     GLSDREESVYAVIPLSAEPVRTWMYDGMRGQDGSTAMELCRELPWIRTDHYVRSQNVKE
                     FPVLTAMNAASMLESTDSLGCAGAGKHADSGLRAVYLPEVERLSYDLASLCRQRYSPES
                     DFVLKRVTPSDLAVLLREAADRLAYPNDSQSPCRSDPLVSLYCCLYNVEGIPDGAYRYD
                     RTEHALRCIAPGDHRLRLQEGMSLHNVNLFQVPICIHVAGDRNYYRSAFGYRGYRMQQM
                     EAGMLVHGLLLAASAIGMGGRPLLGFSPENSDDLYSLTGQGKTSLIQIPIGHYRQRPRL
                     EGGLHS"
     gene            complement(11592..13535)
                     /locus_tag="GGC63_RS30425"
                     /old_locus_tag="GGC63_006286"
     CDS             complement(11592..13535)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013877478.1"
                     /locus_tag="GGC63_RS30425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GGC63_006286"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_192705482.1"
                     /sec_met_domain="YcaO (E-value: 2.5e-84, bitscore: 277.2,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 4.4e-126, bitscore:
                     414.0, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTGVAVIGEGQLAELVCGELSSLCRLARRSDFKEGVPEGMGLAL
                     VLSDAWHPLLHREAEEVFRSLGIPWLRGFVAFGEGAIGPLVRPGLTGCSQCADTRHLMA
                     GRDRKEMWMLEQRLTEHGGVPHDAWASRTGLLQMAHLILKECRAVLEGGRSRLEERMLF
                     LDMKSLRASSHFFLPDPLCPVCSQLPEDTPAGAQITLQPSPKVDRASFRSKSLKDLAGV
                     LVQDYLDIKTGFLNGKMMDFVSPFADVSVNLPLFDHDEVTAGRTHSYASSELTAIMEGL
                     ERYCGMEPRGKRLVIRDSYRNLADSALHPAAAGLYATEQYERPHFPFKPFHPDDPIDWV
                     WGYSFGRQSPILVPLQLAYYTSPCGQGFVYETSNGCALGGSLEEAIFYGIMEVVERDSF
                     LLTWYARLPLPRLDPFSAGDSELELMLHRLKAVAGFDVLLYNATMENGIPSVWALAKNT
                     KPNGLNLICAAGAHPDPVRAAKSSVHELSGMMLTLNGKFEENREQYARMLHDPSLVRGM
                     EDHSMLYSLREAEERLHFLLAGDRPLRSFEEEFKRPPEHPDLTDDLKDVLQAFRRLQLD
                     VIVVDQTTPELKLNDLHCVKVLIPGMLPMTFGHHLVRLTGLDRVLKVPQQLGYTKRPLL
                     PEELNPYPHPFP"
     gene            complement(13532..15457)
                     /locus_tag="GGC63_RS30430"
                     /old_locus_tag="GGC63_006287"
     CDS             complement(13532..15457)
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03693"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009676365.1"
                     /locus_tag="GGC63_RS30430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GGC63_006287"
                     /product="putative thiazole-containing bacteriocin
                     maturation protein"
                     /protein_id="WP_192705483.1"
                     /sec_met_domain="TIGR03693 (E-value: 1.7e-211, bitscore:
                     697.0, seeds: 2, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     5.2e-51, bitscore: 164.0, seeds: 5, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 5.1e-14,
                     bitscore: 45.5, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSITPAARLKVKEDTFFLPVPDEGVYFRNNVGTFRMEGAMIDRW
                     IEKLVPMFNGEHTMADLTNGLSSPHLERVYEIAEVLYRKGFVRDVSQDIPHQLTDGIMK
                     KFAGQIAFLESFGDSGAYRFQCYRQADVLAVGSGPMFVSLVAALLESGLPKIHMLITES
                     VPTNRERIVELANQARRTDPEVEVREIEQRKEGADGWREMVEPYQSIVYVSQKGDIDEF
                     RLLHDVCKTEKKLLLPAMCLHQTGMAGPVVHPGSEGCWESAWRRVHPASVWKDPELHSF
                     STTAGAMLANVIVFELFKSMTGQSEPRNSFFLLDLETLEGSWHSFIPHPMVNGFETNRA
                     IQAPDLQLDGREETLVQGDPNRLLSYMSRLTSPQSGILHLWEEGDLRQLPLSQCRVQAV
                     DPLSEGPAALLPEQIGVGLTHEEARREAGLLGIEAYVARWAEKLVHTNEVIGIGAGATR
                     AEGIVRGLQAHLSQQQSMQLRKRVPSAARVPAGRVEDERCRYYLQQLSAWRRDPVIAFG
                     EEIAGFPAVWVGFGDGWYGGSGLNKTAALRKALQGALLGLQNGSVPPADQVQTASSVRI
                     VREVPGEITFPSIEGWSHSRSMQEALETISSQGKQLFVVDLAVEPFLKEELQGVFGVLL
                     REGGSR"
     aSDomain        complement(15161..15457)
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_GGC63_RS30430_Heterocycloanthracin_C_
                     RRE.1"
                     /evalue="8.80E-52"
                     /identifier="RREFam011.1"
                     /label="GGC63_RS30430"
                     /locus_tag="GGC63_RS30430"
                     /protein_end="99"
                     /protein_start="0"
                     /score="164.0"
                     /tool="antismash"
                     /translation="MTSITPAARLKVKEDTFFLPVPDEGVYFRNNVGTFRMEGAMIDRW
                     IEKLVPMFNGEHTMADLTNGLSSPHLERVYEIAEVLYRKGFVRDVSQDIPHQLT"
     aSDomain        complement(15191..15436)
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_GGC63_RS30430_Thiopeptide_F_RRE.1"
                     /evalue="8.80E-15"
                     /identifier="RREFam004.1"
                     /label="GGC63_RS30430"
                     /locus_tag="GGC63_RS30430"
                     /protein_end="89"
                     /protein_start="7"
                     /score="45.5"
                     /tool="antismash"
                     /translation="ARLKVKEDTFFLPVPDEGVYFRNNVGTFRMEGAMIDRWIEKLVPM
                     FNGEHTMADLTNGLSSPHLERVYEIAEVLYRKGFVRD"
     gene            complement(15637..15954)
                     /locus_tag="GGC63_RS30435"
                     /old_locus_tag="GGC63_006288"
     CDS             complement(15637..15954)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002071895.1"
                     /locus_tag="GGC63_RS30435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GGC63_006288"
                     /product="heterocycloanthracin/sonorensin family
                     bacteriocin"
                     /protein_id="WP_079912205.1"
                     /transl_table=11
                     /translation="MNEFQNDLQQLNVSQFQASDMTPWVDESQYQAAPFPMGADPNDPS
                     RLCVGFCAGFCGGFCGVFCSGFCAGVCGGFCGGFRCGGFRCGGFRCGGFRCGGFCGHRC
                     R"
     misc_feature    complement(16020..16036)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 21.5"
                     /tool="antismash"
     misc_feature    complement(16073..16089)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.93"
                     /tool="antismash"
     gene            complement(16294..16611)
                     /locus_tag="GGC63_RS30440"
                     /old_locus_tag="GGC63_006289"
     CDS             complement(16294..16611)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GGC63_RS30440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GGC63_006289"
                     /product="hypothetical protein"
                     /protein_id="WP_192705484.1"
                     /transl_table=11
                     /translation="MKLFTKEIKNIKVEGRLFHCIIDQTPQLEAVIFKIYPASTKTSYC
                     QMSFSWTAAWSVTFHKPSVCASLIRYALGSGWDPSLEKNRWEIPDADFLIHKLQLDNLE
                     G"
     gene            complement(16670..17677)
                     /locus_tag="GGC63_RS30445"
                     /old_locus_tag="GGC63_006290"
     CDS             complement(16670..17677)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013775.3"
                     /locus_tag="GGC63_RS30445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GGC63_006290"
                     /product="phosphotransferase"
                     /protein_id="WP_192705485.1"
                     /sec_met_domain="APH (E-value: 1.1e-27, bitscore: 90.8,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDQQQAIQAAVRKAYFHKDQDIRTKPVPYGVNNTTCYVLSGEQKY
                     VFRIYDNRHDEQPIQFELNVLASLKRQGLSFEVPAPVPNQEGQWITRLDNGKLGVLFHC
                     IPGERPRPEDAYRFGRAAGELSVALGSIEVSGKPPYRGGSYHLYEVHPLISKEMLHESL
                     SRPADPEDAQAAEFMLQEVVSMEKKKESFSRMPHQLVHGDLALSNMLIHDGRISGILDF
                     EFCSPDVRAMELAVGLMSFVQEESSFLTRAESIISGYSEQASLTAEEIGMLPSLIRLRY
                     IGSYIHHLGRSAAGVGAFDAARKRLHSFLKLSEALVRTEEALLQLGSKYLAARF"
     gene            complement(17697..18554)
                     /locus_tag="GGC63_RS30450"
                     /old_locus_tag="GGC63_006291"
     CDS             complement(17697..18554)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012472.3"
                     /locus_tag="GGC63_RS30450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GGC63_006291"
                     /product="aldo/keto reductase"
                     /protein_id="WP_192705486.1"
                     /transl_table=11
                     /translation="MLYRRLGVTDVQIPVIGQGTWKLGEDPSNAGREIEALRFGLENGM
                     TLIDTAEEYAKGGSERIVGEAVADVRKEVFLVTKVSAKHCSYEGVLQAAEASLERLRTG
                     YIDLYLQHWPSPQFEVAETMSAMAELVDRGWVRYVGVSNFSPELMMEAQRALGKHPLVC
                     NQVGYHLNDRSVEKDILPYCRSNGITVMGYSPFGYAPEVFGKKGFPAPGTKERVILEQI
                     GARHGKTAHQVALNWILRQEGMVTIPKAAGIEHIRDNRNAIGWELDVTELELIESAFPV
                     TAGD"
     gene            complement(18657..18821)
                     /locus_tag="GGC63_RS30455"
                     /old_locus_tag="GGC63_006292"
     CDS             complement(18657..18821)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GGC63_RS30455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GGC63_006292"
                     /product="hypothetical protein"
                     /protein_id="WP_192705487.1"
                     /transl_table=11
                     /translation="MNNIALICPTHDPAGGNVAFIRTCVGQLREIYRDIYITVSDESDN
                     RVVRELVPA"
     misc_feature    complement(18872..18888)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 20.89"
                     /tool="antismash"
     gene            complement(19037..19855)
                     /locus_tag="GGC63_RS30460"
                     /old_locus_tag="GGC63_006293"
     CDS             complement(19037..19855)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015846835.1"
                     /locus_tag="GGC63_RS30460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GGC63_006293"
                     /product="PPK2 family polyphosphate kinase"
                     /protein_id="WP_192705488.1"
                     /transl_table=11
                     /translation="MLKNYIWPRGKKKKLSQYDPEDTGLAASKEEAAEAVEKLKEDLQQ
                     LQDILFAQKKYSVLIVFQGMDCSGKDGVIKKVLSGVNPQGFKAIAFKKPTLDEAAHDFL
                     WRTHKEVPARGYITAFNRSYYEDVLITRVHEQIDDEEAEQRFKHIKHFEKLLSDHNTVV
                     IKLFLHISKDFQISKIEQRLKDPSKTWKFDPNDLLERNFWDSYEKVYEDVFNNCSFKHA
                     PWHIIPSNHRWYRDYLVLSIIVDELRKLPLEYPEPDAQVKERILLLPDSK"
     misc_feature    complement(19884..19901)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 17.63"
                     /tool="antismash"
     gene            complement(19971..20207)
                     /locus_tag="GGC63_RS30465"
                     /old_locus_tag="GGC63_006294"
     CDS             complement(19971..20207)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GGC63_RS30465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GGC63_006294"
                     /product="hypothetical protein"
                     /protein_id="WP_192705489.1"
                     /transl_table=11
                     /translation="MTHKAEEVFRCPWRFQCFTCNGKFLLDPSDPQYRKVKTKQTKYYV
                     CRSCNSSIQGEAVKQTGLDPKLLDPKGYDKFIP"
     gene            complement(20315..21286)
                     /locus_tag="GGC63_RS30470"
                     /old_locus_tag="GGC63_006295"
     CDS             complement(20315..21286)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015734356.1"
                     /locus_tag="GGC63_RS30470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GGC63_006295"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_192705490.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 8.3e-24, bitscore:
                     78.0, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 3.8e-15,
                     bitscore: 49.4, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLQIGFVGTGGFTKFHCNLLAKMDGVQIRAFCATNQEKADRLAA
                     EWQGAEGYDSIHRMLDETSLDAVYICVPPMAHGEIETALIERGIPFFVEKPVGLDLELP
                     HAILQKVQEKKLITSVGYHFRYMDSTQRAAAVLAERTIGMGLGYWMGGMPRVAWWRKQD
                     GSGGQFIEQTTHIVDLMRYLMGEAVEVYAAYGSRFMHTLEEGVTTPDVGTVTIKLASGA
                     VATISNTCMLPAGGPTGLHLYTDQGIMELTQGGLKDIGKTTVCEYKNQSNPYARAHEAF
                     LHAVRTGDTSGILSTYEDAVKTQAIAVAALQSAERGVPVRLG"
     gene            complement(21335..22342)
                     /locus_tag="GGC63_RS30475"
                     /old_locus_tag="GGC63_006296"
     CDS             complement(21335..22342)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013431.3"
                     /locus_tag="GGC63_RS30475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GGC63_006296"
                     /product="aldose 1-epimerase"
                     /protein_id="WP_192705491.1"
                     /transl_table=11
                     /translation="MSQASIQHVLFDDVPSIQLDAGGYRAVIAYAVGSNMVELSRPAEG
                     LSFLRTPDNGELLRQKSQRYGLPPLFPPNRIIDGKFSTPYRDYVLPLNSSDGAHFMHGI
                     LHKRPWRIESEKVLENGAAEVVLVMDMGKDGEMYPYFPHEFTYELTYTLSEQGLHQLVR
                     ITNHSHEPMPLGVGFHTALRVPFHKEGREEDYRLAISVGEEWDLTQLFVSTGKLLPLSE
                     ADRALRGEGIAPTGEPYAKHFISSAVERNGKPFSGAVLKDTARNISLVYEVDPQYGHWT
                     VWNDDGKSGFTCPEPQTWTNNAPNVPLPGEVTGFRLLEPGETWSAWTKLFAELS"
     gene            22544..23104
                     /locus_tag="GGC63_RS30480"
                     /old_locus_tag="GGC63_006297"
     CDS             22544..23104
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1278: PadR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015513.3"
                     /locus_tag="GGC63_RS30480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GGC63_006297"
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_192705492.1"
                     /transl_table=11
                     /translation="MTGQDAILGLLMRKSMSGYDIKQQFEELLSYFFDASFGTIYPTLS
                     KMEKEELITKESIEQQGKPNKNVYTITEKGKAQFHSYLESKLQDNVLRSDFMVRMFFGQ
                     FADSELIQSWMEEAILREEAHLVRLKKDYDRFGKYMTPTQEICIQIGIASAESNLKIVK
                     EGLAKIRQTEQGERPATNQIEEE"
ORIGIN
        1 tgaatagacg attgacacag gaaatgtaag cgtgttaatt tagtagtgtg aattagtcct
       61 agtttaggat taattgtccg catcctatta aaatgcagag gtgaactcca ttatgtcaat
      121 gttagactgg atcgtgttgg ggctgttttt ccttctcatg gtgggcatcg gggtttggtc
      181 ttttcgccaa atcagcggta ctcaagactt ttttgcggca ggcggtaaga tgccttggtg
      241 gctgtccggc atttctcatc acatgtccgg ttacagcgcg gctgtctttg tcgcctatgc
      301 gggtgtcgct tatacttacg gattcacgct gtacgtatgg tgggccatcc cggtatccat
      361 agcggtattt gcaggcgccg cccttatcgc tccccgctgg gcccggctgc gccaacggat
      421 gaatatcgaa tcccccatgg agtatctttc caccagatac aacgtgccta cccagcaatt
      481 gatggcctgg agcggcgtgc tgctcaagct gtttgacgtc ggggccaaat gggccgccat
      541 cgccgttatc ctcaatgtat tcgccggggt cccgttaaat ctgggcatct ttttatccgg
      601 cttgatctcc cttatttact cagctatcgg cggcttgtgg gcggatgcct ggaccgactt
      661 tgcccaattc atcgttcagc tcattgcagg aatcgccatg ttcgtcatcg tggtcatgaa
      721 gctcggcgga atggaagcga ttacagacat ttgggataag ctcccccctt cccacagtca
      781 gcctttggtc ggtccgtata ccttgggatt cgtccttgcc tacgttctga ttgacttcct
      841 tagctacaac ggcggcacat ggaacctggc gcagcgctac atcgcttctc cgaacggttc
      901 cgaggcgcgc aaagcggcct tgctgtccgg tgtgctgtat ctggtatggc ctctcatcct
      961 gttcttccct atgtgggccg cccccctctt ctatcaaaac ttgaaggatc cgacccagtc
     1021 ttactcgatg atgacgatgg atctgctgcc gcacggcttg atcggcctgg tgctggcctc
     1081 catgtttgcc catacgatgg ctatgaccac gtcggatgcc aatgccatta cagcggtaat
     1141 tacccgcgat atattgcctg taatgtccaa gcgataccgt tcgcttagcg agaaagcagc
     1201 gcttcgtgtc gcccgcgggg cgatgatcac cttcgtggtg cttaccctta ttatagcggt
     1261 gtactccagc accttcggcg gcatattgaa cctgcttatc gtctggttcg gcgctctggt
     1321 cggtccgatc tcgatcccga tgctgctcgg cttgatcccc gccttcaagc gcagcgattc
     1381 tactgcggcc atagtatctt gggcggccgg gatcgtcacc ttcgttatcg tcaaatatgt
     1441 gattactgtt agtacagcaa cactggtggc ttctcccgtt gttgtttcgg ccattctgtt
     1501 tatcggcatg ggctggctca aaggcagcgc cccggttgct cctaaggttg aagagctcct
     1561 gcaatcgctt agtgccgatg cgaaggaagc aaattctcca gaccacggta tgaaagctta
     1621 aatgaaccaa atcatggggg caagtatagt cggactgaac ctttgcaaaa cttgctccca
     1681 tctacaggag gaacttggta tgaacagcat catgaacgaa gcttgggacc cccgtacgct
     1741 gctgtcattt tataaacgcc acctgctgga agacctgctt cccttctgga aacatgcagt
     1801 agatcagcgt cacggcggcc tgtttacctg ctttaccaat tcgggaagcg accttgtcaa
     1861 cacagataag tatacctggt cacagggacg attcctctgg atatggtcac ggattgcaag
     1921 attaaccgac cagggtgtac tgccagggga agcttctacc tttcaacaag aagcggagca
     1981 tgcagcggcg tttctcaaga accatgtcgt cctcagcaac gggaattgtg cctttctcct
     2041 gacggaggac ggccgcatga aggagagcgt tccgggcgag ggcttcgaca cgagctttta
     2101 tgcggattgc ttcgtcgtgc tcggatttgc cgaattatcc cgctgcagcg gacgacagga
     2161 gctcgcgaac gacgcgctcg aacgatatga ccggatacgg cttcgcttgc gggatgggca
     2221 aatccgcagt gagccctatc caatccctca aggcttgaag tcccactctg tcaccatgat
     2281 tatgctgaat atttccgagc agcttatgga ggcgctgcag catttccgcc atcctgcata
     2341 cgagcgtctc aagaaggatt gcctccatta tgcggaatcc atcataacag agttccgcat
     2401 gcctgatcaa cggattgccg agctgctccc tgtcagcggc gagacacctc ctaccgttct
     2461 atgccgccac gtcaatcccg gccatacgct ggaatgcatg tggttcgtca ttcagacagc
     2521 caggcagctg ggccgggagg atctcattac tcaaacgctg cccgtcattc gaaaggcctt
     2581 tgagctggga tgggatacgg agcaaggagg cctgctgcgc tttgtcgacc aggacggcgg
     2641 cccgccgaca ggccagcgga caggagaccc ttacgaagcg ctgattctgg atacatggga
     2701 caccaagctg tggtggcccc attccgaagc gctatatgcc tctttattgg cctatgagct
     2761 gtccggcgat ccgggcttca aggagctgta taggcagacg catgattatg tctttcggac
     2821 ctttccccac acggaccctc ggatcgggga atggattcag attcgcgacc gcagcggaga
     2881 gccgatggac aaagtcgtgg cgctgcccgt caaagacccg ttccatatta tacgtaacgt
     2941 gctgctgatc atcgagcttt attcagatgc ttcgagcgca taaggaggca ggctatgaca
     3001 agatccttac atctcggaac cgccaaagtg gatattactc cagccatgcc cgtccccctt
     3061 gccggcttcg cccaccgaac cgggacattc gaacatattg cccagccgtt atacgcgaga
     3121 attcattgct tgcagcagtc tcgagtttcg ggcagcaaga caacagtgct cttggtatcg
     3181 gcggatttga tttggtgggg cagcgacctt gtgaaccggc tctcgcccaa gctgcgggaa
     3241 cggtacggat tggattcggt gctgctccat gcaacccata accattccgg tccccagaca
     3301 agcggttgct ttaccgatgc tcttggcagg ccggatcctg gatatttgca ggaattggag
     3361 cgaaggctcg agagcggcat cgaacaagcg cttcaaacca tggagcccgt tatgatggaa
     3421 aagggaaccg gacactgccg gatcgggttt aaccggagaa aagacatcga cgggcatatc
     3481 gaaatggccc cgaacgagaa cggccccgtc gatccggaag tcaccgtaat ccggttccgt
     3541 acccccgacg gaaggaccaa agggctgttc gttcattata cctgccatcc cactacgacg
     3601 ggggatagcg aaatttctcc cgagtactgc ggagcggctc tggaacggat cgagcaagct
     3661 ctgggcagcg gcgtcaccgg cgctttcctg caaggatgct gcggggatat tcggccggcc
     3721 ctggttcagg acggtcaatt ttatcggggc caccgcatgg aggtggagcg cttcgggagc
     3781 tggctgtgtg aagaggcgct tcgcatctgc tgccagccga tgaacgagct cgctccagct
     3841 ttattgccca gtcacaccct ggtgctgccg ctgccctttc agtccgtccc gaccgtggaa
     3901 gagctcgagg agcaggcgaa gctggcagac attcagggag agcgggcccg cctgctgctt
     3961 ggtcagccta cccgcaggca aggctccatt ccgctcgaaa ttacgaggct gactttagca
     4021 aaggagcttt cccttattac ctttaatgcg gaaatggtgg tggattacgg tctttttgta
     4081 aaaaaagcat cccgcggaac tatgcttccg ctcggctaca ccaacggaat gatcggctat
     4141 gtgccaacgg cggagcagct ggaacagggc ggctatgaat cacacggctc tgtcccctat
     4201 ttcgggctgc aggcgccttt tcagccgcag attgaaagcc tcatccggaa tgccctagcc
     4261 caagagataa gagaggagat tgaaccatga acgaaaccat acacccctta agaacgcaaa
     4321 ccgtcgaccg gctgcaagtt cacgtctacg agaatagaga gcagcttgga aaagcggccg
     4381 gcagcgatgt cgccgccaaa atgaaggagc tgctcggcag caagagcagc atccggatga
     4441 tttttgccgc agcgccttca caaaacgaat ttctgcagac gttgaagcag gccgacggga
     4501 tcgactggtc ccgcgttacc gtgtttcaca tggacgaata tatcgggctt gccccggaag
     4561 ctccgcagcg attcagcgcc tttctgcggg aacggctgtt tgacgaagtc aagccgggga
     4621 acgtccattt gatcaactgc tcgggtgata tcaacgagga atgccagcgg tacgctggat
     4681 tgctagggga tgctcccatc gatatcgtct gcctgggtat cggagagaat ggtcatatcg
     4741 cctttaatga tccgcctgtc gcagacttta acgatccggc actcgtcaag agtgtcgagc
     4801 tcgatttgcc gtgccggcag cagcaggtca acgacggctg ctttgccagt ctgcaggacg
     4861 tccctaccca tgctctgacg ctgactatcc ctgccctatt ctccggagcg cacctatact
     4921 gcatggttcc gggtgtcacc aaaaccgcgg ccgttcaaag gacgctgcgc ggtcccattt
     4981 ctacggaatg tccttctacg attctccgcc ggcattcgga ttgtacgcta tatctggata
     5041 aagacgcata cggagacctc ggttaggaga tgaaggacat gtcgggaaac gtaacgacgg
     5101 tagaaggaat tcactacagg acaaaggaac ccgttacggt tcacatcgag cgcggccgaa
     5161 tctcggctat tcagcccttg tcaacgaaga agaaagcagc actgccctgg atcgctcccg
     5221 ggctggtaga tttgcagatc aacggatact gcggatccga ttttaatacg ataccgattg
     5281 ccgctggagc ggtacaacgc gctacacgcg ggctttggaa ggaaggcgtg acctcttatt
     5341 atcctacggt cattacgaac ggggacgcag agatcgagca agccatgcag tctattgccc
     5401 gcgcctgtga tgaggatcct gccgcgcatg ccggggttgc cggcatccat ctggaaggcc
     5461 ccttcatatc gccggaggac gggccccgcg gcgcacacga cagcctgtat acgaaagcac
     5521 cgagctggcc tttattccag cggtggcagg aggcggctcg aggccggatc aagatcatca
     5581 cgctgtcgcc ggaatggccg ggatcggtcg aattcattga gcggtgcgtg gagcagggcg
     5641 tgaccgtctc catcggccac acctccgcct ctcccgggca aatcgacgct gccgtcaaag
     5701 caggtgcgcg aatgtccact catctgggca acggcgctca cttgatgctc ccccggcatc
     5761 ccaactatat atgggagcag ctaagccagg acgggttaac ggcctgcctt atcgccgacg
     5821 gcttccattt gccggaatcg gtattgaagg tcattttgcg caccaaggga gaacgcgcgc
     5881 tgctcgtcag cgatgccgtc tatttaagcg gcatggagcc tggcgtgtac gataatcata
     5941 tcgggggccg ggtcgtcctt acccccgaag ggcgtcttca tctggcagac aaccccggtc
     6001 ttcttgcggg atcggtgcag ctcctgccct gggggatctc ccatctggca agaagcggaa
     6061 tggcagcgct cgaggaggcg tgggatatgg cttcgatacg ccccgccgct ttcatgcagc
     6121 tgccttcgca gaacgggctc tccgtcggtt cgcctgccga tctggccctg ttcgaatgga
     6181 accgtcagag cctcagcatc gttcaaacct ataagaacgg gaatcgcgtc ttcgattcca
     6241 ctacctccag ccgggaggga agtctatgag cacggccgca atgacccaat accttcataa
     6301 aattattcag catctggagc tgcttcatca ggaagaacag gcttcgatcg cccgggccgc
     6361 ccgcatgatg gcggagcata tcaagcaaga caagctcgtc tatgcctatg gccccggtgg
     6421 ccactcgaac ctgggctcgc aggagatttt tttccgtgcc ggggggctta tgcatatcag
     6481 tgccatcctg gacgaaggta cgctgctcag cgggggcgcc ctaagatcca tggccgtcga
     6541 gcggacgcca gggtatgcaa atatcgtact ggatgactac ggcttgaagc agggggattt
     6601 attgatcatt attaattcct atggcattaa ttcggctacg atagattcgg ccctggaggc
     6661 caaagcccgc ggaattcgaa cgatcggcgt cacttccgtc cggcacgcgc tggctacgcc
     6721 cgcggaccat gtggcgcggc atccgtccaa gcacaatttg cacgatctgg tcgatatcgt
     6781 gctggatacc aagattgaag tcggagacgc ggtagtggag atcgaggggc ttgatcagcg
     6841 ggttgccgcc atgtccacct tcgccaatgc gtatctctta aattcgctgg tcgcggaaac
     6901 catcgagctg ctggtcaagg acggcatccg cccgcccatc tggatgagcg gcaatgccag
     6961 cggcggcgac gaatccaact cgcgcttcat tcagcagttt aaaggacgaa tcaagaagct
     7021 atagtcaggc acttggtaga ggaatctcac aaagcggagc cttggaatcg aagctttaca
     7081 ggaagtcccg aaattctatc taaaaaagtc ctttggaact aacccaaagg actttttcta
     7141 tttacatttg caataattca gcgcatagtg aacctatact tgtctatgca atcatttcag
     7201 gaggacagct catgcaaggt tataacgttc taatgatcta caatcatagc atggaccggc
     7261 tgctcatgtg caaacggttg aaaaacccgt acaagggact cagcaatctg gtaggcggaa
     7321 aaatcgagac gggagaagcc gggttcgaag ccgcttaccg ggagctgtta gaggaaaccg
     7381 gcatttccca agaggatgtc actttgcatc atgtgatgga ttttacctat tacctgcagc
     7441 aatgctacgt cgaagtctat gccggaagat tgaagcatga tatcgccgtg acaggggatg
     7501 aaaacgaatt atactggtcg gacctggatc aggatttttt cgatatgtcg cagtatgccg
     7561 gcgaaggaaa tattggacat atgatcgaac aagtgaacat gtacaaggag atccttttga
     7621 cggattaatt ccgctcttga aagaccggcc gggtgaagat gagattaagc agcacgacga
     7681 ggcctgctcc gatcagcgtt gccgttattc ggtccagaag cgctagaccg tcgagcggtt
     7741 ttcccgcgtc catcagcaaa aaaataagcg gggtcatggt tgcggagtac agcaaaaaaa
     7801 taagcggggt catggttgcg gagtacagca aataattccg cgccttcaac cacggtctca
     7861 acccggcaag caaccccacc gccacgacga ccgcccattc aggcagcgta taggcaaaga
     7921 gcgcactgac ggcagctacg ccgatgacgg tgccggttac cctttgaatc gttttgaccg
     7981 gtaccgggtc cgctttccgt tccgtcaaga tcgccgcagt cagtacgatc caataaaaat
     8041 gatgcccggg ccatacccac cggattccct cggctagacc aagacagcac cctaatcgaa
     8101 gcgtatactg ccagccggcc agctggcgcc aaaaggcccg ggcgtaagcc tatttcacct
     8161 atggtaatgc cgcctagtgc agctatcatt ccaagaggaa gatggcccca tgcggcgaag
     8221 agacacacag gaacgcccat ccctatacag gaggaaatga gctctgcagg ctccacattc
     8281 gcctctctcg accattgcag ggcttgctgc caatgcttgt ttctatccgg cttatccacg
     8341 cttcacgtga gcataaggag ctttatccga cacaagattc aagacgatgc cgtgctccaa
     8401 tagcgcctta agcccgcaaa gcacaatcgt aaacccttcc gtcgatccta tcgcctgctt
     8461 cacgacatca tccgcttcgc cttgaaagcc gatattggta atcgtaacga aggtttcctt
     8521 ctcccccttg gaagtaaaga tccactccac cctggacccg aaatggatga gaatgcgctg
     8581 attcttctcg atctccagca cttcaacctc tgcggatgct ccatacatgt cccattccca
     8641 cttaacccgt gcccctggct ccagtcttcc gctgctgtgg gtaaaccaga atttcgtagt
     8701 cactgcagga tcaatgaaag cctcaaatac ttcttcaacc ggtctccgta tcaacatttc
     8761 cgcctttgca accggcgcct gatttttcca tgccgccatc ttggattctc ccttcagctt
     8821 caagattcat ctaacttata tcatagcata cgaaggtaaa aaaagagcac tgcctgtccg
     8881 gcagctactc tgtttggaaa cccatgagtt taaaaccatt gcaatgtaaa ccggcggata
     8941 atcccaccct cctatttcgc atatttccgc tatactaggg tgttcattac tcatgaaaaa
     9001 tcctcatttt atgaagcctc tcgctcttaa atcctctttg ttcagcagaa caccgtcctt
     9061 ggagttcata gcgcgcagaa tgccttgttc cgtgtttaaa aattcgggtt gcagcttctt
     9121 taccccattc aacggggtga aatcgagctt aacttgatca ttggctatct ccgctgcggg
     9181 aatccattcc tcttcgatag gatagcccag gttttttatt tcggatttgt tgacgaacag
     9241 attgctctgg tacaccagca tggacaattt tccgcttggc cgttgataaa gcttagggac
     9301 atccggttgc tggtactggt cgctgaaggc gaacggaaag ccaaccccgt aaacgcctat
     9361 cttcagatgg gtcgtcgagc tatcgccgga cagcgatgcc ttgatgtcgt tgccctcata
     9421 aaatcggagg agatcaggta ccttgatcca ttcggtcaag tccggggctg cagtcaattc
     9481 ctggtacatg ctatggttag ccttcttcgg gtccagctga atggttcgcg tcgcttcgtc
     9541 gtaatcaagc tcgtagccga gtaaagcagc gacctccctt accggtaaat aggaggttcc
     9601 gtctacgacc aatggactgt tcttgagttc cttctcttca ccgttcacct tgaatacgaa
     9661 ttgggcaata gcagcttgta cagactccga tgccgccgag acggtcgtag ccgttaagcc
     9721 gatcatgacg cctatggaaa gtggaagaat gatttttttc atatctagga ctcctttctt
     9781 tatataaata taccatatat taacacaacg tttcgtgaac attaatgtta gtaagctttt
     9841 ggagatacaa aaaaatccgt tctttacgaa cggatagatt gtcgagaaac ctatacaggt
     9901 tgagaaaggc actatatccc gcgctgggct cccacctggc ataattcgat gagatccaag
     9961 ctccctgggc ctctaagcaa atttcgaagc cggtgaatcg ttaactgtgc agccccccct
    10021 ccaaccgggg ccgctgacgg taatgaccga tcggaatttg gatcaggctg gtcttccctt
    10081 gcccggtcaa tgaatacaga tcatcactat tctccggact gaagccgagc aagggcctcc
    10141 ctcccatgcc gatggcggac gccgccagca acaagccgtg cacaagcatc cccgcttcca
    10201 tctgctgcat gcgatacccg cgataaccaa acgccgatcg ataatagttc cggtcacccg
    10261 ccacatgaat acatatcggc acttgaaata aattcacgtt atgcagagac attccctcct
    10321 gcagccgcag ccggtggtct cccggagcga tacagcgcag tgcatgctcc gttctatcgt
    10381 agcggtaggc tccgtccgga atcccctcca cgttatacaa acaacaatac agcgatacaa
    10441 ggggatcgga ccggcacgga ctttgcgaat cgttgggata ggctagccta tcggccgcct
    10501 ctcgtagaag cacagccagg tctgacggtg tgactctctt cagaacaaaa tccgattccg
    10561 gcgaataccg ctgccggcaa agcgatgcca gatcatagga caaccgttcc acttcaggca
    10621 ggtatacggc ccgcagcccg ctatctgcat gcttccccgc tcccgcacag cctaaggagt
    10681 ccgttgattc cagcatggac gcggcattca tcgcagtcag cacaggaaac tccttgacgt
    10741 tctgtgaacg tacatagtga tccgtccgga tccaaggcag ctccctgcat aactccattg
    10801 cggtgctccc atcctgtccc ctcataccgt catacatcca ggtcctcaca ggctctgccg
    10861 ataaagggat gaccgcatag acgctctcct ctctgtcaga cagcccgagc agatgattaa
    10921 ccccccggtc cagaaattga taacacatgg ccgagtcgta cccgaactgc cgggccgctt
    10981 cacggagctg tccgatcagg actcccgtat ccaagccttg cagccgataa gcaaagttgt
    11041 gatatttgta aaagtttttc caaaacataa cggaaaccat aacggctccg cagcacccct
    11101 ccatctcgca ttggccgcca agcgcccggg tcaggtaagc atcgtaattc ccctcccgaa
    11161 gccgaaccag ccggtggtgc gccgcatcgt aatggtatat tccctccggg acatccgacg
    11221 tcttccaata tacataaagt tcattcggat acaatccgcc gccggaagga acgaagcgcc
    11281 ggtacatcgg gacctgggtg cctccataca tcgtgacgtc cgcaggaaac tggctgactc
    11341 gggtcagacc gtatgcatac cacagcaaat ggcctaagga taacaaatca ggaaaagtcc
    11401 tcgttggacg atcagtcagc gataagggca tttccgccga taaaggaaca accggcaagc
    11461 cgcgatacag cttgtaggtc agcggcgcat cctcccaatc gacttcccaa tccggcggcc
    11521 gggactcatc atttgccgta tggaggctgt gcaggaatcg gtccagactc atcatttttc
    11581 ctcctcacgg tttaggggaa cgggtgcgga taaggattaa gctcctcggg gagtaatggc
    11641 cgctttgtat agcctagctg ctgcgggacc ttcaataccc ggtccagccc tgtcagtcgg
    11701 acgagatgat ggccgaacgt catcggaagc atgcctggaa tgagcacctt gacgcaatgc
    11761 aggtcgttga gctttaattc tggagtcgtt tgatctacta cgatgacatc gagctgcaac
    11821 cgccggaatg cttgaaggac gtctttcaaa tcatccgtca aatccgggtg ctccggcgga
    11881 cgtttgaact cttcctcaaa ggaccttaga ggccgatccc ctgccagcaa aaagtgaagc
    11941 cgttcctcag cttcccgcag gctgtacagc atagaatgat cctccatacc gcgcaccagc
    12001 gacggatcgt gaagcattcg ggcatactgc tcccgattct cctcgaattt tccgttcagc
    12061 gtgagcatca tccccgataa ttcatgaacc gagcttttcg cagcgcgaac cggatcaggg
    12121 tgagcccctg cggcgcaaat caggttaagt ccgttcggct tcgtattttt ggccagcgcc
    12181 caaacgctag gaatgccgtt ctccatcgtc gcgttataca gcaatacatc gaagcccgca
    12241 accgccttca ggcggtgaag catgagctcc agctccgaat cgcctgcgga aaaaggatcg
    12301 agccggggca gcggcagcct ggcataccag gttaacagga aggaatcccg ttccacgacc
    12361 tccataatgc cgtaaaaaat agcttcctcc agactgccgc ccagcgcaca gccgttcgag
    12421 gtctcgtaga caaagccttg tccgcagggc gaggtataat aagcaagctg cagcgggacc
    12481 aagattggac tttgcctgcc aaacgaatag ccccataccc aatctatcgg gtcatcgggg
    12541 tgaaagggct tgaacggaaa atgaggccgc tcatactgct ctgtggcata cagtcccgct
    12601 gccgcaggat gcagagcgct atcggccaga ttgcggtagc tgtcccggat caccagcctt
    12661 ttgccgcgag gctccatgcc gcagtatctc tccagcccct ccataatggc ggtcagctcg
    12721 ctgctcgcat atgaatgcgt tcgccccgcc gtcacctcgt catgatcgaa caagggaaga
    12781 ttgacgctga catcggcaaa cggagataca aaatccatca tttttccgtt caggaagccg
    12841 gtcttgatat ccagatagtc ttgaaccaga actcccgcca gatctttcaa tgacttgctc
    12901 cggaagcttg ctctgtccac cttgggactc ggctgaaggg ttatttgggc tcccgccgga
    12961 gtatcttcag gcagctggct gcagaccggg cataacgggt caggcaaaaa gaagtgactt
    13021 gaagctctca atgatttcat atccaggaac agcatccgtt cttccagccg ggaacgtccg
    13081 ccctcaagca ctgcacggca ttccttcaag atcagatgtg ccatctggag caatcctgtc
    13141 cgggatgccc atgcatcatg cggaactccg ccatgctccg tcaggcgctg ctccagcatc
    13201 cacatttcct tgcggtctcg tcccgccatc agatgccgcg tgtcggcgca ctgcgagcat
    13261 ccggtcaggc cgggtcgaac cagcgggcct atcgcccctt cgccgaaggc aacgaacccg
    13321 cgaagccatg ggatgcccaa ggagcggaac acctcttccg cttcccgatg aagtaacgga
    13381 tgccatgcat cgctcagcac cagggcgagc cccattcctt ccggcactcc ctccttgaaa
    13441 tcacttcgac gcgccagtcg gcacaaagag gacagctcgc cgcatacaag ctccgccagc
    13501 tggccttctc cgataacagc taccccggta ttcatcggga tcccccctct cgcagcagca
    13561 caccgaatac gccttgcagc tcttccttca aaaacggctc cacagccaaa tcgactacaa
    13621 agagctgctt gccctggctg ctaatcgtct ccaaagcttc ctgcatggac ctggaatggg
    13681 accatccttc tatagaaggg aacgtgattt cgcccgggac ttccctaacg atacgcacgg
    13741 acgaagctgt ctgcacctga tccgcaggag ggacagagcc gttttgcagc cctaacagcg
    13801 caccctgcag cgccttccgc agagccgcag tcttattcaa gccgctgccg ccgtaccagc
    13861 catcgccaaa cccaacccac acggcaggaa agcctgctat ttcctctccg aaggcgatca
    13921 cagggtccct tctccaggcg gacagctgct gcaaataata ccggcaccgt tcgtcctcta
    13981 ccctgccggc cggcactcgt gccgcggacg gcacccgttt cctgagctgc atggactgtt
    14041 gttgggacaa atgagcctgc aagccgcgta caattccttc cgcccgggtt gcccccgcgc
    14101 cgattccaat cacttcgttg gtatgtacaa gcttctccgc ccatcttgct acatacgcct
    14161 caatccctaa taatcccgct tcccggcggg cttcctcatg cgtcagcccc actccgatct
    14221 gctcaggcag cagagccgcg ggcccttccg acagcggatc aaccgcttga acgcggcact
    14281 gggacagggg aagctgcctc aagtctccct cctcccataa atgaagaatt cctgactgag
    14341 gtgaagtcaa ccggctcata tacgatagca gacggttggg gtccccctgg accagggtct
    14401 cttccctgcc gtcaagctgc agatccggcg cctgaatcgc ccgattcgtc tcgaagccgt
    14461 tcaccatggg atgagggatg aaggaatgcc agcttccctc caatgtttcc agatccaaca
    14521 gaaagaatga atttcttggt tcagattgtc cggtcatcga cttgaacagc tcaaatacga
    14581 tgacattcgc gagcatcgcc cctgccgtgg tggagaagga atgaagctca gggtccttcc
    14641 atacagaggc tggatgcacc cggcgccatg ccgactccca gcacccctcg gaacccggat
    14701 gcacaacagg tcctgccatg cctgtttgat gcaggcacat agccggcagc aaaagcttct
    14761 tctctgtttt gcatacatcg tgaagaagcc ggaattcatc gatatcccct ttttgggaca
    14821 catacacgat ggattggtat ggctctacca tctctctcca gccgtcggct ccttcctttc
    14881 gctgctcaat ttccctaact tcgacctccg ggtccgtacg gcgggcttga ttggccagct
    14941 ccacaatccg ctcccggttc gtcggtactg attcggttat gagcatatgg attttaggaa
    15001 gaccagactc caacagtgca gcgaccagcg aaacgaacat aggcccggac ccgaccgcca
    15061 atacgtcagc ctgacgatag cattggaacc ggtacgcgcc cgaatcgccg aagctttcca
    15121 aaaaagcgat ttgccccgcg aactttttca taatcccatc cgttaattga tgcggaatgt
    15181 cttgacttac atcccgaacg aacccttttc ggtacaatac ttcggcaatt tcatacaccc
    15241 tctccagatg agggctcgac aagccgttcg tcaaatccgc catcgtatgc tccccgttaa
    15301 acatggggac cagcttttcg atccatcggt cgatcatcgc gccttccatg cggaaggtac
    15361 cgacattgtt gcggaaatac acaccctcat ccggaaccgg gagaaaaaac gtatcctcct
    15421 ttaccttcag tcgcgcagca ggggttatac tggtcatttc actcctccta acgattgcga
    15481 attgccagtt tatggtacaa tgtattgtat attatatgta ggcagtttcg tccgacatgc
    15541 cttgccatga agaaaatgcc cctgacaaca tcatgttgtg aggggcatag ttcctcggca
    15601 ggactgccga acgtagacaa ctcagaaact aatggcttaa cggcagcgat ggccgcagaa
    15661 tccaccgcag cggaatcctc cgcaacggaa accaccgcaa cggaatcctc cacagcgaaa
    15721 accaccgcag aagccgccac agacgcccgc acaaaagccg ctgcaaaaca caccacaaaa
    15781 gccgccgcag aagcccgcac aaaaaccgac acataacctg gacgggtcgt taggatccgc
    15841 acccattggg aatggagctg cctggtactg gctttcatcg acccaagggg tcatgtcgct
    15901 cgcttgaaat tgggatacat tcagttgttg aagatcattt tggaattcat tcatcgggta
    15961 aaacctccaa gtaatttttt ctggttacgg tgaaagcagg atggaaggtt cgatcgcttc
    16021 tgaaacataa ttccaatgta tggagcatct ccgcttttgt tactgagtca accgcccatt
    16081 ttatgggcat ttgtaccaga gcaagctctc gatgctgcag agtgttgatt caagagggag
    16141 ttcgcagggc atcttgcgtt gcaaatgaaa aaagatgact cccggtcact tcggaaatca
    16201 tctattggaa cagcttatat gaaaaatgac tcaaaccgca tacgcctgaa ctagctcgtg
    16261 aatcgcccgc tccaaatcca ttttagaacg atactaccct tccaggttat caagctgcaa
    16321 tttatgaata agaaaatcgg catcgggaat ttcccatcta tttttttcaa ggctgggatc
    16381 ccagccgctt cccaacgcat accgtattaa gctggcacaa acactaggct tatgaaacgt
    16441 tacagaccag gccgccgtcc aggaaaacga catctggcaa tacgacgttt tggtgcttgc
    16501 gggatagatt ttgaatatga cggcttcaag ctgcggggtt tgatcgatga tgcaatgaaa
    16561 taaacgtccc tctaccttga tattctttat ttctttcgta aaaagcttca tagaacaact
    16621 ccattccgaa tcggcttgcc atcctgtaag ttgctgctat tgcactggct taaaagcgcg
    16681 ccgccaaata cttggaacca agctgcagca atgcctcctc agtccgtaca agagcttccg
    16741 aaagcttcaa gaatgaatgc agccttttgc gtgccgcatc gaatgctccc actcctgctg
    16801 ctgaacggcc aagatgatgg atatacgacc ctatatacct cagtctaata aggctgggaa
    16861 gcatgccgat ctcctcggcg gttaacgaag cctgttcgct gtatccggaa attatgcttt
    16921 ccgctctggt aagaaaggaa ctctcctctt gaacgaatga cattaagccc acggcaagct
    16981 ccatcgctct gacgtccggt gaacaaaatt caaagtccaa tatgccggaa atgcgtccat
    17041 cgtgaatcaa catattgctc aatgcaagat cgccatgcac caactgatga ggcattcgtg
    17101 aaaagctctc tttcttcttt tccatcgaaa caacctcttg cagcataaat tccgccgcct
    17161 gagcatcctc cgggtccgcc ggccgagaca ggctttcatg tagcatctct ttggaaatga
    17221 gaggatgaac ctcatataaa tgataggagc ctccgcggta tggcggcttg ccggaaactt
    17281 caatggagcc cagtgcaacc gacagctccc ctgcagcccg cccgaaccga taagcatcct
    17341 ccggacgggg ccgttctccc gggatgcaat gaaataatac gccaagcttg ccgttatcca
    17401 gtctcgtaat ccattgtcct tcttgattag gtacaggggc agggacttca aaggataggc
    17461 cttgccgctt caatgaagcc agcacgttca gctcgaattg aatgggctgc tcgtcatggc
    17521 ggttatcgta gatgcggaaa acgtactttt gttctcctga aagcacataa cacgtagtgt
    17581 tattcactcc ataagggacg ggcttcgtcc ttatgtcctg gtccttatga aaatacgcct
    17641 ttcgtactgc cgcttggata gcctgttgct gatccacttt gtttccctcc gctctgttaa
    17701 tcccccgctg ttacgggaaa ggcgctttct atcaactcca gctcggttac gtccagttcc
    17761 cagcctatag catttctatt atctcttata tgttcgatac cggcggcctt cgggatggtc
    17821 accatgcctt cctgacggag gatccagttt agcgcaacct gatgagctgt cttcccgtgc
    17881 ctggctccga tttgctcaag aatgactctt tctttcgtac cgggtgctgg aaagcctttc
    17941 ttgccaaaca cctcgggagc ataaccgaaa ggagagtagc ccataacggt tattccattg
    18001 cttcggcaat aaggcagtat atccttctca accgatctat cgttcagatg atagcctacc
    18061 tgattgcaga ccaggggatg cttgcccaaa gcgcgctgtg cttccatcat cagctcaggg
    18121 ctaaaattgc tgaccccaac gtaccggacc cagcctctat cgaccaattc ggccatcgcg
    18181 ctcattgtct ctgccacctc gaactgcggg cttggccaat gctgcaaata aaggtcgata
    18241 tagccggttc gcagacgctc cagactggcc tccgccgcct gcaaaactcc ttcgtacgag
    18301 caatgcttgg cggacacctt cgtaaccagg aagacctcct tgcgcacgtc cgcaacagcc
    18361 tcgcctacga tgcgctccga gcctcctttg gcatattcct ctgccgtatc gatcaaggtc
    18421 atcccatttt ccaaaccaaa ccttaaggct tcgatttctc tcccagcgtt actcgggtcc
    18481 tccccgagct tccaggttcc ttgaccgatt acaggaattt gtacgtccgt cacgcctaat
    18541 cttcggtata acatcaagcc tcatcccttt ccatggatta acagcgttgg tgtgcttatt
    18601 ttatcgctac gattatgatg caaggctaag ccgtccgccc ccattacact tgaatcttat
    18661 gctggaacca attcacgaac cactctgtta tcgctttcat cgctcactgt aatgtagata
    18721 tctcgataga tctcacgcag ttgccccaca caggtacgaa taaaggctac attgccgccg
    18781 gcaggatcat gggtaggaca gatcaatgca atgttgttca tataccattt ctccttgctt
    18841 tctttattcc aacctcatct tccattcagg gttggtatta ttttacaagc cggtcttata
    18901 aggcagcaag aggttttttg attataggca aacttacctg aggaaaagcc gatcagagga
    18961 actagatgcg ggatatcgat tgaacaaaaa aagagccgcc agcacattag catgttgacc
    19021 gctcttcttg ggatcatcac ttgctgtccg gaagcagcag gattcgttcc ttcacttgcg
    19081 catccggctc gggatattcc agcggcagct ttcgcagctc atcgactata atgcttagaa
    19141 caagataatc acggtaccag cgatgattcg aagggatgat atgccatgga gcgtgcttga
    19201 agctgcaatt attgaaaaca tcctcgtata ccttttcata ggaatcccag aaattgcgct
    19261 ccagcaaatc attaggatcg aatttccacg ttttggacgg gtcttttagc ctttgctcga
    19321 ttttggaaat ttggaagtct ttggatatat gaagaaacag cttaatgact acggtgttat
    19381 ggtcgctcag cagcttttca aaatgcttaa tgtgcttaaa gcgctgttct gcctcttcat
    19441 catcgatctg ttcgtggacg cgggttatga gcacatcctc gtagtaagaa cgattgaagg
    19501 cggtgatgta gccccgggca ggcacttcct tgtgggttct ccataaaaaa tcgtgagccg
    19561 cctcatccag cgtcggtttt ttgaaggcta ttgccttgaa gccctgcgga ttcacaccag
    19621 acagcacctt tttaataaca ccgtccttgc cgctgcaatc catcccttga aatacaataa
    19681 gcaccgaata tttcttttgg gcgaatagta tgtcctgcag ctgctgcaga tcctccttca
    19741 gcttctccac agcttcggcg gcttcttcct tactcgcggc taatcccgta tcctccggat
    19801 cgtattgact tagcttcttt ttctttccgc ggggccagat gtagtttttc agcacaagat
    19861 cagcctcctg aagtatccat agttttacaa gaatgtaacc tgactcaaat ctaggctgca
    19921 gccaatctct ctgatgtttt taccctttca gccgtgcggg cgaaaaggag ttacgggatg
    19981 aacttgtcat agcctttcgg atcaagcagc ttagggtcca agccggtttg cttcacggcc
    20041 tctccttgga tcgacgaatt gcaggatcgg catacataat atttggtttg cttggttttg
    20101 accttcctat actgcgggtc gctaggatca agaagaaatt tgccgttgca ggtaaagcat
    20161 tgaaacctcc agggacatcg aaagacctcc tccgccttat gcgtcacctc tctagtatcc
    20221 catatttttc cacgcttgac tgtgaccatt atttgaactt gccggtaaaa aagactaacg
    20281 gagcgtcctg cggcgaacac tccgtttatt ctcatcagcc tagacgtaca ggcactcccc
    20341 gctcggcaga ttgaagagca gctacagcaa tcgcctgtgt tttgaccgca tcctcgtacg
    20401 tggatagtat gccgctggta tcgcctgtcc gtacggcatg aaggaacgct tcatgcgcgc
    20461 gagcgtaagg gttgctctga ttcttatatt cgcacaccgt cgttttgccg atatccttca
    20521 agcccccctg tgtcagctcc ataatgcctt gatccgtata cagatgcaga cctgtcggcc
    20581 ctcctgcagg aagcatgcac gtgttcgaga tagtcgctac cgcgccgctc gccagcttga
    20641 tcgtcaccgt tccgacatcc ggggtcgtta ctccttcttc caaggtatgc ataaaacggc
    20701 tgccgtaggc tgcgtacact tccaccgcct cgcccatcag atagcgcatc aaatcgacga
    20761 tatgcgtcgt ctgctcgatg aactgcccgc cggagccgtc ctgcttgcgc caccaagcca
    20821 cccgtggcat tccgcccatc cagtagccga ggcccatccc gatcgtacgc tcggctaaca
    20881 ccgccgccgc acgctgcgtg gaatccatat accggaaatg atacccgacg gaggtaatca
    20941 gctttttctc ctgaaccttt tgcaaaattg cgtgaggaag ctccagatca agccccaccg
    21001 gcttctctac aaaaaagggg atgccccgct caatcaacgc ggtttcgatt tctccatgag
    21061 ccatcggggg aacgcaaatg tagacggcgt ccagggacgt ctcgtccagc atccggtgaa
    21121 tgctgtcgta gccttcggct ccctgccact cagcggctag ccggtccgcc ttctcctggt
    21181 tcgtcgcgca gaaggcccgt atttgcactc catccatttt ggccaataaa ttgcagtgaa
    21241 acttcgtaaa gcctccggtg ccgacaaatc cgatttgcag tgtcatcgac tcactctccc
    21301 cttaatgatt ccatcatgct tcttccttac aaatctagct tagctctgca aatagcttcg
    21361 tccatgccga ccaggtctct cccggctcca gcagccggaa tccggtcact tcccctggga
    21421 gcggcacgtt aggcgcgtta ttcgtccagg tttgcggctc aggacatgta aatccgctct
    21481 tgccgtcatc attccaaacc gtccaatgcc catattgagg atcgacctca tagaccaggc
    21541 tgatgttcct tgccgtatcc ttcagtacag cacctgaaaa cggcttgccg ttccgctcca
    21601 cggcgctgct tataaaatgc ttcgcatacg gctcccccgt tggagcaatt ccttccccgc
    21661 gcagtgctcg atctgcttcg gataatggca gcagcttgcc ggtagacacg aacaattgcg
    21721 tcaggtccca ttcttcccct acggaaatcg cgagacggta gtcttcctcc cgtccttcct
    21781 tgtgaaacgg gacgcgcagc gccgtatgaa atccaacccc aagcggcatc ggttcatggc
    21841 tatggttcgt aatccgcacc agctgatgaa gaccctgctc tgacaaggta taggtgagct
    21901 cataagtaaa ttcatgagga aaatagggat acatttcacc gtccttaccc atgtccataa
    21961 caagaaccac ctcggctgcg ccgttctcaa gaaccttctc cgattcgata cgccaaggac
    22021 gtttgtgcaa aatgccatgc atgaaatgag ccccgtccga gctgttcaac gggagaacat
    22081 aatcccggta tggcgtggaa aatttcccgt caataatccg gttaggagga aataaggggg
    22141 gcagcccgta gcgttggctt ttttgccgca gaagctctcc attatccggg gtgcgaagaa
    22201 agctcaaccc ttcggcaggc cggctaagct cgaccatatt gctgcccacc gcgtacgcaa
    22261 taacagcccg gtatcctccg gcatccagtt gaatcgaagg cacatcatca aaaagtacat
    22321 gttgaatcga agcctggctc atgaaaaagc cctcctgaaa tctatgtagt agttggaata
    22381 aagacgatat cctgacttca ttatccaata aaacccctgg aagcgcaaaa aggttttgaa
    22441 tattttgggc aaaataaggc aagtctatat attgacacga tatatatcgg atgttaatat
    22501 aacctcacga ttgatatatc agttcgatat aggagtgaca aagatgacag gtcaagacgc
    22561 aattcttggt ttattgatgc gcaaaagcat gtccggctat gacattaaac agcaattcga
    22621 agagctgctt tcctactttt ttgacgcaag cttcggtacc atctacccta ccctaagcaa
    22681 gatggagaaa gaggagctca ttaccaagga aagcatcgag cagcagggaa agcctaacaa
    22741 aaacgtgtac accatcacgg aaaaaggcaa agcgcaattc cacagctatt tggagagcaa
    22801 gctgcaggat aacgtgcttc gctctgattt catggttcgg atgtttttcg gccaattcgc
    22861 cgactctgag ctgatccaaa gctggatgga agaagctatc cttagagagg aagcgcacct
    22921 cgtgcgattg aaaaaagact acgatcgctt cggcaaatac atgacgccga cgcaggaaat
    22981 ttgcatccaa atcgggatcg ccagcgcgga gagcaatctg aagatcgtca aggaaggatt
    23041 agctaaaata aggcaaacgg agcaaggcga acgccctgca accaaccaaa ttgaggagga
    23101 atgatagatg agcaagcagc ataacggttt gatcttatta gccatggcgc tcggtctgct
    23161 aatgtcatcg ctagataata ccatcacttc ggccgcggtg agccacatta ttaaagacat
    23221 cggcggcttt gaaagcatga gctgggtatt ctccgcttac atgcttgctg cgaccagcac
    23281 catgctggtc ttcggcaaaa tgtccgatct gttcggacgc aaacgatttt acctgatcgg
    23341 gatcggcttc ttcctgatcg gctccgcctt gtgcggcatc tcgcaaaata taacacagct
    23401 gatctggttc cgcgctcttc aaggcatcgg ttccggagcg ttaatgccta tcagctttac
    23461 gatcatctac acgctgttcg cggaccccaa gcaagccgcg aagctgtccg gcgtctttgc
    23521 ggccatcttc ggcct
//
