LOCUS       NZ_JACSPO010000001     21080 bp    DNA     linear   CON 29-AUG-2024
DEFINITION  Oceanitalea stevensii strain Sa1BUA1
            NODE_1_length_1311955_cov_23.248817, whole genome shotgun sequence.
ACCESSION   NZ_JACSPO010000001
VERSION     NZ_JACSPO010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Oceanitalea stevensii
  ORGANISM  Oceanitalea stevensii
            Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
            Bogoriellaceae; Georgenia.
REFERENCE   1  (bases 1 to 1311955)
  AUTHORS   Gilroy,R., Ravi,A., Getino,M., Pursley,I., Horton,D.L.,
            Alikhan,N.-F., Baker,D., Gharbi,K., Hall,N., Watson,M.,
            Adriaenssens,E.M., Foster-Nyarko,E., Jarju,S., Secka,A., Antonio,M.,
            Oren,A., Chaudhuri,R., La Ragione,R.M., Hildebrand,F. and
            Pallen,M.J.
  TITLE     A Genomic Blueprint of the Chicken Gut Microbiome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1311955)
  AUTHORS   Gilroy,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-AUG-2020) Microbes in the Food Chain, Quadram
            Institute BioScience, Norwich Research Park, Norwich NR4 7UQ, United
            Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.1
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 221x
            Sequencing Technology             :: Illumina NextSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014837105.1-RS_2024_08_29
            Annotation Date                   :: 08/29/2024 01:02:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,251
            CDSs (total)                      :: 3,198
            Genes (coding)                    :: 3,182
            CDSs (with protein)               :: 3,182
            Genes (RNA)                       :: 53
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 16
            CDSs (without protein)            :: 16
            Pseudo Genes (ambiguous residues) :: 0 of 16
            Pseudo Genes (frameshifted)       :: 2 of 16
            Pseudo Genes (incomplete)         :: 14 of 16
            Pseudo Genes (internal stop)      :: 0 of 16
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:07:08
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 500140
            Orig. end                         :: 521220
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JACSPO010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21080
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21080
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21080
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11080](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11080)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(81..902)
                     /locus_tag="H9624_RS02360"
                     /old_locus_tag="H9624_02345"
     CDS             complement(81..902)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (21-139). E-value: 2.1e-12.
                     Score: 39.3. Matches aSDomain:
                     nrpspksdomains_H9624_RS02360_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010549433.1"
                     /locus_tag="H9624_RS02360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9624_02345"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_251838302.1"
                     /transl_table=11
                     /translation="MTTSPRRPLSAPAESSVLGGRALVTGGTSGLGLEFARALAARGLS
                     LVLVARNRERLEKTAEQLRWRYGVEVETLVADLAARDDVDAVAARLLDADSPVDVLVNN
                     AGHGVHVPLLAEDLTEVERSLDVMVRAVLVLGNAAGRAMVTRGRGVIVNVASVAGLVPM
                     GAYSAIKSWVGTYSESLSLELAGTGVQATALVPGWVRTEFHERAKIRTSAIPGFLWLEA
                     DRVVADALDDVEKGRVRSVPSLRFRVIAFLAAHAPRPLVRRATALIQGGRS"
     CDS_motif       complement(447..497)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_H9624_RS02360_0002"
                     /evalue="5.50E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="H9624_RS02360"
                     /protein_end="152"
                     /protein_start="135"
                     /score="-0.2"
                     /tool="antismash"
                     /translation="GNAAGRAMVTRGRGVIV"
     aSDomain        complement(486..839)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_H9624_RS02360_PKS_KR.1"
                     /evalue="2.10E-12"
                     /label="H9624_RS02360_PKS_KR.1"
                     /locus_tag="H9624_RS02360"
                     /protein_end="139"
                     /protein_start="21"
                     /score="39.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="ALVTGGTSGLGLEFARALAARGLSLVLVARNRERLEKTAEQLRWR
                     YGVEVETLVADLAARDDVDAVAARLLDADSPVDVLVNNAGHGVHVPLLAEDLTEVERSL
                     DVMVRAVLVLGNAA"
     CDS_motif       complement(747..836)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_H9624_RS02360_0001"
                     /evalue="8.90E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="H9624_RS02360"
                     /protein_end="52"
                     /protein_start="22"
                     /score="24.8"
                     /tool="antismash"
                     /translation="LVTGGTSGLGLEFARALAARGLSLVLVARN"
     gene            complement(899..3166)
                     /locus_tag="H9624_RS02365"
                     /old_locus_tag="H9624_02350"
     CDS             complement(899..3166)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (11-327). E-value:
                     4.9e-52. Score: 168.5. Matches aSDomain:
                     nrpspksdomains_H9624_RS02365_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012398926.1"
                     /locus_tag="H9624_RS02365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9624_02350"
                     /product="HAD-IB family hydrolase"
                     /protein_id="WP_251838303.1"
                     /sec_met_domain="NAD_binding_4 (E-value: 9.8e-51, bitscore:
                     168.5, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHSPLEHAHVLVTGATGFVGQAVVEKLLAAYPTTRVSILVRPRGD
                     LSAQRRAEKLLRKPVFRSWRDSVGEENALAAFTERVTVISGDLEDVPELPDDLDVVVHS
                     ASSVSFDLPVDEAFAANVAGPVNLYERLLATGTDPHVVHVSTSYVAGLRKGVAEERSLD
                     HDVDYRTELRSALAARQTAEEASRRPEVLEPLLRQADADHRRAGPRAVSQAAEAARAAW
                     VREELVHHARTRAESLGWPDVYTFTKAMGERVAETLWQGGGHRLSVVRPTIIESSFRHP
                     YPGWIDGFKVADPLIAAYGRGMLPEFPALADTVLDVIPVDFVVNAILAAAAAPPQTGEA
                     SYYQVSSGITNPLRFGKLYEYVREYFSANPLKDSSGSHVSVPSWSFPHRGAVERAVRRR
                     EKAVEIADRAVGRLPARARTREWMSTLYKARRDINTLRKFTALYQPYTQIEVIFDDART
                     RALHASLPPERQVEHGFDVTEIDWRHYLQEVHIPGVPGLMRGERPKAGTPRVTELPERS
                     DVVAVFDLQRTVIAATLVEQYLWVELATQPPSGWPKALGNLVALGPRYLQAEMRDRGDF
                     IRTFMRRYAGTHEAELRAAILERVQDSLRRDVLTEAVAQIRAHRAAGHRTVLVTGEIDV
                     FVEPLAPLFDVVVAGQMETDDDGRWTGHLLASPLVGESRATWLTRYARDEGLDLSASYA
                     YGDSYADRPWLEVVGNPRVVNPDAQLYRYARAQRWPVLSWTTTVEGRVAPVLRSLKEGV
                     QR"
     aSDomain        complement(2186..3133)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_H9624_RS02365_NAD_binding_4.1"
                     /evalue="4.90E-52"
                     /label="H9624_RS02365_NAD_binding_4.1"
                     /locus_tag="H9624_RS02365"
                     /protein_end="327"
                     /protein_start="11"
                     /score="168.5"
                     /tool="antismash"
                     /translation="VTGATGFVGQAVVEKLLAAYPTTRVSILVRPRGDLSAQRRAEKLL
                     RKPVFRSWRDSVGEENALAAFTERVTVISGDLEDVPELPDDLDVVVHSASSVSFDLPVD
                     EAFAANVAGPVNLYERLLATGTDPHVVHVSTSYVAGLRKGVAEERSLDHDVDYRTELRS
                     ALAARQTAEEASRRPEVLEPLLRQADADHRRAGPRAVSQAAEAARAAWVREELVHHART
                     RAESLGWPDVYTFTKAMGERVAETLWQGGGHRLSVVRPTIIESSFRHPYPGWIDGFKVA
                     DPLIAAYGRGMLPEFPALADTVLDVIPVDFVVNAI"
     CDS_motif       complement(3095..3139)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_H9624_RS02365_0001"
                     /evalue="9.90E-03"
                     /label="PKSI-ER_m5"
                     /locus_tag="H9624_RS02365"
                     /protein_end="24"
                     /protein_start="9"
                     /score="8.7"
                     /tool="antismash"
                     /translation="VLVTGATGFVGQAVV"
     gene            complement(3240..3998)
                     /locus_tag="H9624_RS02370"
                     /old_locus_tag="H9624_02355"
     CDS             complement(3240..3998)
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0051353 - positive regulation of
                     oxidoreductase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012876935.1"
                     /locus_tag="H9624_RS02370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9624_02355"
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="WP_251838304.1"
                     /sec_met_domain="Fer4_12 (E-value: 1.4e-06, bitscore: 24.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 4.3e-16, bitscore: 55.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTVAAGHPPAPARAGDLQVAGMTPLSTVDWPGRLAATVFCQGCP
                     WDCSYCHNPALIAPRTPGTLPWEDVLAFLRRRRRLLDAVVMSGGEATRQGALLPAVREV
                     RGLGFAVGLHTAGPYPRRLAALLGDVDWVGLDLKALPEDYHDVVRRPGAGHLAWECLDL
                     LVASGVDHEVRTTVAPGSPAARHAVEIARRARDAGARAFALQVVRTAGTRAEFAAAHSS
                     ADHRAWREEVTSLDEQIAALGLPHYELRPG"
     gene            complement(3995..5827)
                     /locus_tag="H9624_RS02375"
                     /old_locus_tag="H9624_02360"
     CDS             complement(3995..5827)
                     /EC_number="1.17.4.2"
                     /GO_function="GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005055152.1"
                     /locus_tag="H9624_RS02375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9624_02360"
                     /product="ribonucleoside triphosphate reductase"
                     /protein_id="WP_251838305.1"
                     /transl_table=11
                     /translation="MDHRPTHVDPITTVEEYLDRSDWRVNANANQGYSLGGMMLNTSGK
                     VVANYWLDRVYAPDAGRAHREGDLHIHDLDMLAGYCAGWSLRRLLEEGFNGVPGAISAA
                     PARHFSSAVGQIVNFLGTLQNEWAGAQAFSSFDTYMAPFVRLDDMTYPQVKQCVQELVY
                     NLNVPSRWGTQTPFTNLTFDWTCPPDLREQVPLIGGEPCDFTYGELQHEMDLVNRAYME
                     VMTEGDANGQVFTFPIPTYNITKDFDWDAENTERLFAMTAKYGLPYFQNFISSDLDPGM
                     IRSMCCRLQLDLRELLKRGNGLFGSAEQTGSLGVVTVNMARLGYLHAHDEPGLVRRLDE
                     LMDIARDTLELKRVVIQEHIDGGLFPWTRRYLGTLENHFSTIGVNGMNEMVRNFTLGEY
                     DLTDPRGHALCARLLDHVRERMVEYQEATGHLYNLEATPAEGTTYRFAKEDRKRFPGIL
                     QAGTETNPYYTNSSQLPVGFTDDPFEALERQEELQGKYTGGTVLHLYMSERISSAQACK
                     EIVRRALESFRLPYITITPTFSVCPNHGYLAGEHHTCPRCGVDREEPVACEVWTRVMGY
                     FRPVSSFNIGKKGEYAEREMFTEQAAVSSPVAAP"
     misc_feature    complement(5783..5797)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     misc_feature    5895..5909
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.12"
                     /tool="antismash"
     misc_feature    5927..5941
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 23.42"
                     /tool="antismash"
     gene            complement(5998..7917)
                     /gene="pknB"
                     /locus_tag="H9624_RS02380"
                     /old_locus_tag="H9624_02365"
     CDS             complement(5998..7917)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013117293.1"
                     /locus_tag="H9624_RS02380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9624_02365"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_251838306.1"
                     /sec_met_domain="Pkinase (E-value: 1.8e-49, bitscore:
                     164.6, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQRTVSDPMLGRLVDGRYEVRARIARGGMATVYRALDRRLDRTVA
                     LKAMHPHLAESADFVARFRREARSAARLNHPGIVAIYDQGLADDTSYLTMELIEGHNLR
                     TELRRQGALPLGRALDVVDGVLDALACAHRAGVVHRDVKPENVLLERDGRPKVTDFGLA
                     RAVTEATAASTGTVLGTVAYLAPEIVTSGVADARADVYAVGIVLFELITGSQPFVADQP
                     IRVAFQHVNDGVPRPSSRVEWLPAEVDELVAALTARDAEDRPADADAALALLRRTRATL
                     DDPTLARRADVAPAVEEEDAEATGGSATDVTPLPAGTVALPIGAIHAGAPDPGPAGPAR
                     RRRRRRVFALTMVLALLALAGGGSWWWFTQGPGAYVTVPEVVGLAEDDAVAVLSEAGID
                     LTVEREHHDTVPENEVVSADPAPGDRVRTDGTVVLHVSRGILMVEVPELVGLTQDEAAA
                     ALEEAQLGVGQVETPYDDDVPEGEVMSASQEAGEVIPYDQPVDLVVSAGREPVELVSVV
                     GADTDTAVSDLENAGLSAVVEEDYHPEVPAGRVVSQSPEPGEDVQLYRGDEVTVTVSLG
                     PQPVELPDLIGRQVGAATDELEAAGFVVKVERVLGGIFGTVRSMSPDAGELAVPGTTVT
                     LTVV"
     gene            complement(7994..9463)
                     /locus_tag="H9624_RS02385"
                     /old_locus_tag="H9624_02370"
     CDS             complement(7994..9463)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013117292.1"
                     /locus_tag="H9624_RS02385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9624_02370"
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_251838307.1"
                     /transl_table=11
                     /translation="MKARTRTRAPRPAGRTGVGLVLAATTVAAMTVPAGAATAAPAAPT
                     VGATALALTAPATQRSLPTGTYQVRAGDTVSTIAARAGTTVSAIVSANNLNSRALIKVG
                     QVLRLPAAGKAATAAPTRAASSTTHTVAAGDTVSALAKRYGSTVEEIVSANRLGSRALI
                     IIGQRLTIPGASASGVSAAPAANRPAAQSASTHVVRAGDTVSGIAQRYGTTVERIASAN
                     GLSDPGLIRIGQRLTVSGGGSGSAPAAKPAAKPATVPVSSTASRTHVVAAGDTVSGLAS
                     RYGSTTSAIISANNLPGSGLIYVGQRLTVPGGSGGGTSAGGGSTSGGQLVGSTFLGRTY
                     ASDVVGAANTNKATLLSMSVPSRDQMRAMVRSTAVTMGVDPALALAIAQQESGFDMRAV
                     SPANAVGVMQVIPSSGQWASDLVGRRLNLLDPQDNVVAGVAILRQLVRTADNFDQAVAG
                     YYQGLAGVKRNGMYADTRNYVAGIKNLMRQF"
     gene            9620..9985
                     /locus_tag="H9624_RS02390"
                     /old_locus_tag="H9624_02375"
     CDS             9620..9985
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005049107.1"
                     /locus_tag="H9624_RS02390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9624_02375"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_251838308.1"
                     /transl_table=11
                     /translation="MTDSDPRWCSLPEVAELLDVRLRDVRDLLRDHHLAGTRPQEEGPF
                     LVPRDFIVTAEDGAAEPGPVPSLRGTLTLLTDTGFTVDEAVEWLLSEQEELGTTPIAAL
                     RAQRIHEVRRLAQTFAV"
     gene            complement(10001..11080)
                     /locus_tag="H9624_RS02395"
                     /old_locus_tag="H9624_02380"
     CDS             complement(10001..11080)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013117290.1"
                     /locus_tag="H9624_RS02395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9624_02380"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_251838309.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.2e-40, bitscore:
                     134.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAPTAGLATLVTDRVATALREHTRPFESLEGVEELLSAGEALLG
                     GGKRLRAAFCTAGWTAFTDRPVTAGSAPVLAGSALELFQGAALAHDDLMDGSLTRRGLP
                     AVHRRMAGEHAERGWLGDPDRHGAAGAILLGDLLLSVSSVEMDLARRLVDDAASTRARA
                     TWDLMTTEVAVGQYLDVRSQVLPWNEQDDVDRALTVVQHKSARYSVEHPLVLGAALAGA
                     PDEALAALRRVGLPLGVAFQLWDDVLGVFGEPEVTGKPAGDDLREGKRTVLLALALRGA
                     DAEQRATLQRHVGRPDLSADDVALLRTVLETTGAVEEHQRLVDSHLDEGLAALDTLGLP
                     AASHEMLTGLARRLTARAA"
     gene            11196..12377
                     /locus_tag="H9624_RS02400"
                     /old_locus_tag="H9624_02385"
     CDS             11196..12377
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025200.5"
                     /locus_tag="H9624_RS02400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9624_02385"
                     /product="DUF4192 domain-containing protein"
                     /protein_id="WP_251838310.1"
                     /transl_table=11
                     /translation="MNTTTITISQPEDIVAYLPYRLGFRPRDSVVLLAMCGERNRLGLV
                     TRADLADIGHPRVGPALVRDVSRLMAEEGAHDVFVVLYSDLPRDRLAADPLVRGALEHL
                     RTLTSWADPPGPWVVGAGTYGCWGTGEECAPATRDAAELDQRPVVATLVLHGLALVPAR
                     EDLAVPRTTDAERRRAATRATREGRRRLAELRARSGGGAALPGAAFGVPGAAPAVDQRE
                     VTEWREEERRRWERLVALAVRGAVLPASELGMLAAALEDNTVRDSVLCSVIHPLAGRVL
                     DRARTEEILDLAMLPGGPPPDQDRVEPAAAVLRALVACVPRRSGALALGLLAWVAWWCA
                     DGARADVLAQQALRARPRTRLAELVDEALAARLPPGWVRTASGDPAAPSPPIR"
     misc_feature    complement(11197..11211)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.72"
                     /tool="antismash"
     gene            12439..12846
                     /locus_tag="H9624_RS02405"
                     /old_locus_tag="H9624_02390"
     CDS             12439..12846
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013883481.1"
                     /locus_tag="H9624_RS02405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9624_02390"
                     /product="universal stress protein"
                     /protein_id="WP_251838311.1"
                     /transl_table=11
                     /translation="MTVVVGYLATPEGEAALETGVAEARRRDARVVVVISRRSRQEQHA
                     DVDAELDALRDRLDDADVAYDVRQLGRGNDVASDLVETAEETGAELIVIGLRRRSPVGK
                     LILGSNAQRILLDAPCPVLAVKPPSTERRSY"
     gene            12908..14299
                     /locus_tag="H9624_RS02410"
                     /old_locus_tag="H9624_02395"
     CDS             12908..14299
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018134385.1"
                     /locus_tag="H9624_RS02410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9624_02395"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_372435081.1"
                     /transl_table=11
                     /translation="MDWRPRETARTGMASYNCRQRTGSKPEPPFPSERLSVSSHAQSTS
                     SRTHAARTSAGGTTASVEETSTKTRAKAPAKSTTAKKPAAKKETSTATKRTATKTTAAK
                     KAALKAVPDVEETTATTGEASETAAAPEAEATTGKESGFVVSDNDDDDAPVQQVVTAGA
                     TADPVKDYLKQIGKVALLNAEQEVELAKRIEAGLFAEEKLASEDVSGKLKRELEWIAND
                     GRLAKNHLLEANLRLVVSLAKRYTGRGMLFLDLIQEGNLGLIRAVEKFDYTKGYKFSTY
                     ATWWIRQAITRAMADQARTIRIPVHMVEVINKLARVQRQMLQDLGREPTPEELAKELDM
                     TPEKVVEVQKYGREPISLHTPLGEDGDSEFGDLIEDSEAVVPADAVSFTLLQEQLHQVL
                     DTLSEREAGVVSMRFGLTDGQPKTLDEIGKVYGVTRERIRQIESKTMSKLRHPSRSQVL
                     RDYLD"
     misc_feature    complement(12949..12962)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.87"
                     /tool="antismash"
     misc_feature    12950..12965
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.54"
                     /tool="antismash"
     misc_feature    12953..12966
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.1"
                     /tool="antismash"
     gene            complement(14353..15147)
                     /locus_tag="H9624_RS02415"
                     /old_locus_tag="H9624_02400"
     CDS             complement(14353..15147)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015780386.1"
                     /locus_tag="H9624_RS02415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9624_02400"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_251838312.1"
                     /transl_table=11
                     /translation="MTDGTGVLTVLTVGQVAERFGVTVRTLHHYDAIGLLSPSARSQAG
                     YRLYTEEDVTRLQHVVVYRRLDFSLEEIAQLLDDGTRPALLEHLRRQRSAVVSRLEELA
                     ELVTAIDRALEKEMTGVNLTKEEQRELFGDGFSDEYAAEAKDRWGDTDAWRQSQQRTSR
                     YTKADWEEIKAEAEEVNAAFVAALEAGEPATSEAAMDAAERARLHIHERFYSLSADFHR
                     NLGDMYVSDPRFTKTYEDIRPGLAQYVRDAIHANADRHAARG"
     gene            15294..16148
                     /locus_tag="H9624_RS02420"
                     /old_locus_tag="H9624_02405"
     CDS             15294..16148
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H9624_RS02420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H9624_02405"
                     /product="hypothetical protein"
                     /protein_id="WP_251838313.1"
                     /transl_table=11
                     /translation="MSTDTSTTRRPLGLRTSDLVTAAATGLLTLPDPARRTPATRFALR
                     TAVAGTTGAGVWLGTDGDSALDLPSRAAFTAGAVGLVYGAAELGEAMDRALQRRLVRMG
                     VRRPRLAMALAGVGASLAVSFLERRAEATDEEDDAPEGPVLRPLPEPVRELVGAILAHT
                     EDYDSLRLRAQLAGAREEVWGEPEDAPQMVELSVPEGAPLAVPHSFTFPVSARFTSARG
                     VPCAARVLVSGGRLAAVVVDLDDDAWEVLAEDWDPAGGDPDPLADVTLPRAQDVILVTE
                     ARG"
     gene            complement(16152..17138)
                     /locus_tag="H9624_RS02425"
                     /old_locus_tag="H9624_02410"
     CDS             complement(16152..17138)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019136975.1"
                     /locus_tag="H9624_RS02425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9624_02410"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_251838314.1"
                     /transl_table=11
                     /translation="MSTAPAPVSGLRWRPITPQDVPDWHGLVRAIEAADDPAERYTPED
                     LHDELLDGSWKDPARDSTIGIDDDGVPRAFGHVQVLPGDVRTVRAFCWGGVHPLWRGRG
                     IGRELLAWQERLGREKIAAARSTGPGRVLVNVDDGLTATERLLDRAGFRRLRVYLELTR
                     PLDAEIAAPALREGLRLVPYDPGLSEPVRLAHNEAFADHWGSEPRDPENWERQSVGGRY
                     FRPSWSFVVLDGDQVAGYSLTSAYEQDWAAQGYSAGWTDLLGVRRPWRRAGVASALLAA
                     TMRALREDGIERADLGVDVENPNRALDLYTGLGYRESRRSLAYGKDV"
     gene            complement(17242..17433)
                     /locus_tag="H9624_RS02430"
                     /old_locus_tag="H9624_02415"
     CDS             complement(17242..17433)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020014335.1"
                     /locus_tag="H9624_RS02430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9624_02415"
                     /product="hypothetical protein"
                     /protein_id="WP_251303393.1"
                     /transl_table=11
                     /translation="MTAPLTAQDRCDRCGAQAYVRVGLPVGELLFCAHHARKHAEALEG
                     VATAIQDETHRLTEDNAR"
     misc_feature    complement(17440..17455)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.55"
                     /tool="antismash"
     misc_feature    17528..17543
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     gene            17652..19787
                     /locus_tag="H9624_RS02435"
                     /old_locus_tag="H9624_02420"
     CDS             17652..19787
                     /EC_number="5.6.2.2"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013771314.1"
                     /locus_tag="H9624_RS02435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9624_02420"
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="WP_251838316.1"
                     /transl_table=11
                     /translation="MPPKSTASPSQYTARHLSVLEGLEAVRKRPGMYIGSTDSRGLMHC
                     LWEVIDNAVDEALEGHGDAIAVVLHPDGSVEVRDNGRGIPVDTVDSVGLSGVEVVFTKL
                     HAGGKFGGSSYAASGGLHGVGASVVNALSARLDVEVDRGGKTYRMTFHRGEPGTYDDRG
                     GAGPEAPFAPFTDASELAVVGKTPRGRTGTRVRYWADPQIFPSTSQFSYDELVTRARQT
                     TFLVPGLTITVRDERRLPGTPGEDGPVEEVFRHDGGVVDFAEFLATDPPVSDIWRLTGS
                     GTFTETVQQLDASGHLRPQEVERTCEVDIALRWGQGYETTARSFVNIISTPKGGSHLTG
                     FEQGLVRTVRKQIEANSRRLKVTAKDPKIEKDDVLAGLTAVVNVRLPEPQFEGQTKEIL
                     GTAPVRGIVANVVDKQLTEILTSPKRHEKAQASAVLEKVVGEMRARVQARLTKEISRRK
                     NALESSRLPAKLADCRTDDVERSELFIVEGDSALGTAKLARSSDFQALLPIRGKILNVQ
                     KASPADILRNAEVASIIQVIGAGSGRTFDLDAARYGKVILMTDADVDGAHIRTLLLTLF
                     FRYMRPLVEAGRVYAAVPPLHRVEIAGSGGKKGEKIYTYSESELHQLLRKLEKQGKRYK
                     EPIQRYKGLGEMDADQLAETTMDPAHRTLRRVSMADAQALAEAERVFELLMGNDVAPRK
                     DFIVAGAGQIDRDRIDA"
     gene            19835..20854
                     /locus_tag="H9624_RS02440"
                     /old_locus_tag="H9624_02425"
     CDS             19835..20854
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.5"
                     /locus_tag="H9624_RS02440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9624_02425"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_251838317.1"
                     /transl_table=11
                     /translation="MPDTLPDRAAPPAHAAVPAPHLGLTWRALTTDDVDHVHALIGRCE
                     AVDQPVLRTARAQVEDVLGRPATGMKADSLGGFDSSGELRAAAFVHAPLGDETHARVFI
                     SASVDPSWRGRGIGRALLTWQDDRARQILATLDPSLPGRIAAYVDEDLEDRRRLYAAAG
                     FSPKRTFREMRLRLTEPPAVVDVPEGYEIRQWSPEIDDAVRDAHNEAFRDHWGSQPVAE
                     TTWAASHRSLEAAWSVVAVHLETGSVAGYALTARHEHQWEALGHTEGYTELLGVLRAHR
                     GSGVARALLSAVLGALYRDGIEVAALDVDMENPSGAHRFYERMGYEPQGARILYTIEV"
ORIGIN
        1 ccggtgccag cgggcgtggt agcggctcag gctggaggcg tcctcgcccc cacggccgcc
       61 ccgtgcggag tccccctcgg tcacgaccga cctccctgga tgagtgcggt ggcgcgccgc
      121 acgagcggcc gcggtgcgtg cgcggcgagg aacgcgatga cgcggaaacg gagggagggc
      181 accgagcgga cccgtccctt ctcgacgtcg tccagcgcgt cggcgacgac gcggtcggcc
      241 tcgagccaga ggaagccggg gatggcgctc gtgcggatct tcgcccgctc gtggaactcg
      301 gtgcgcaccc agcccggcac gagggcggtg gcctggacgc cggtgccggc gagctcgagg
      361 gacagggact cggagtaggt ccccacccac gacttgatcg ccgagtaggc ccccatgggg
      421 acgagcccgg cgaccgaggc gacattgacg atgacgccgc gcccccgggt gaccatcgcg
      481 cggcccgcgg cgttgccgag gacgaggacg gcgcggacca tgacgtccag cgaccgctcg
      541 acctcggtga ggtcctccgc gaggaggggc acgtgcacgc cgtggccggc gttgttgacg
      601 aggacgtcga cgggggagtc ggcgtcgagg agccgcgccg cgacggcgtc cacgtcgtcg
      661 cgcgccgcga ggtcggccac gagcgtctcc acctcgacac cgtagcgcca ccgcagctgc
      721 tcggccgtct tctccagacg ctcccggtta cgggcgacga ggacgagcga caggccccgg
      781 gccgccagag cgcgggcgaa ctcgaggccg aggccggagg tgccgccggt gacgagcgcc
      841 cgcccgccca ggacggagga ctcggcgggc gccgagagcg ggcgccgggg actggtcgtc
      901 atcgctggac gccctccttg aggctgcgca ggacgggtgc cacccggccc tcgaccgtcg
      961 tcgtccagga gaggacgggc cagcgctggg cacgtgcgta acggtagagc tgggcgtcgg
     1021 ggttgaccac acgggggttg ccgacgacct cgagccaggg ccggtcggcg tagctgtcgc
     1081 cgtaggcgta ggacgcggac aggtccaggc cctcgtcgcg ggcgtagcgc gtgagccagg
     1141 tggcccgcga ctccccgacg agcggggagg cgaggaggtg gccggtccag cggccgtcgt
     1201 cgtccgtctc catctgtccg gcgacgacga cgtcgaagag cggggcgagc ggctcgacga
     1261 agacgtcgat ctccccggtg acgaggacgg tgcggtgccc ggcggcgcgg tgcgcgcgga
     1321 tctgggcgac ggcctcggtg aggacgtccc ggcgcaggga gtcctggacg cgctcgagga
     1381 tcgccgcccg gagctccgcc tcgtgggtgc cggcgtagcg gcgcatgaag gtgcggatga
     1441 agtcgccgcg gtcacgcatc tcggcctgga ggtagcgcgg gccgagggcg acgaggttgc
     1501 ccagcgcctt gggccagccc gagggcggct gggtggcgag ctcgacccac aggtactgct
     1561 cgacgagggt cgcggcgatg acggtgcgct ggaggtcgaa gaccgcgacg acgtcgctgc
     1621 gctcgggcag ctcggtcacg cgcggcgtgc cggccttggg ccgctcgccg cgcatgagcc
     1681 cgggcacccc ggggatgtgg acctcctgga ggtagtggcg ccagtcgatc tcggtgacgt
     1741 cgaagccgtg ctcgacctgc cgctccgggg gcagggaggc gtgcagcgcc cgggtgcggg
     1801 cgtcgtcgaa gatgacctcg atctgcgtgt acggctggta gagcgcggtg aacttgcgca
     1861 gcgtgttgat gtcgcggcgc gccttgtaga gcgtggacat ccactcgcgg gtgcgggcgc
     1921 gggcgggcag gcggccgacg gcgcggtcgg cgatctccac ggccttctcc cggcggcgca
     1981 ccgcgcgctc gacggcgccg cggtggggga aggaccacga gggcaccgag acgtgggagc
     2041 cgctggagtc cttgagcggg ttggcggaga agtactcgcg cacgtactcg tagagcttgc
     2101 cgaagcgcag cgggttcgtg atgcccgagg agacctggta gtagctcgcc tcgccggtct
     2161 gcggcggggc cgccgccgcg gcgaggatcg cgttgacgac gaagtcgacg gggatgacgt
     2221 cgaggacggt gtccgccagc gccgggaact ccgggagcat gccgcgcccg taggcggcga
     2281 tgagggggtc ggcgaccttg aagccgtcga tccagcccgg gtaggggtgg cggaaggagg
     2341 actcgatgat cgtggggcgc acgaccgaca ggcggtgccc gccgccctgc cagagggtct
     2401 ccgcgacccg ctcacccatc gccttggtga aggtgtagac gtccggccag ccgagggact
     2461 cggcgcgggt gcgggcgtgg tggaccagct cctcgcggac ccaggcggcg cgggcggcct
     2521 cggcggcctg cgagacggcg cggggaccgg cgcggcggtg gtcggcgtcg gcctggcgca
     2581 gcagcggctc gaggacctcg ggacggcggg aggcctcctc ggcggtctgg cgggcggcga
     2641 gggccgagcg gagctcggtg cggtagtcga cgtcgtggtc gaggctgcgc tcctcggcca
     2701 cgcccttgcg caggccggcg acgtagctcg tcgagacgtg gacgacgtgc gggtcggtcc
     2761 cggtggcgag gagccgctcg tagaggttga ccggcccggc gacgttggcg gcgaaggcct
     2821 cgtccacggg caggtcgaag gacacgctcg aggcggagtg gacgacgacg tcgaggtcgt
     2881 cgggcagctc ggggacgtcc tcgaggtcgc cggagatgac ggtgacccgc tcggtgaacg
     2941 cggcgagcgc gttctcctca ccgaccgagt cgcgccagct gcggaagacc ggcttgcgca
     3001 gcagcttctc cgcgcggcgc tgggcgctga ggtcgccgcg ggggcggacg aggatgctga
     3061 cacgggttgt cgggtaggcg gcgagcagct tctcgacgac ggcctggccg acgaagccgg
     3121 tggcgcccgt gacgaggacg tgcgcgtgct ccaacggtga gtgcatttgc cgaactctat
     3181 agccgagggc cccgagtcca gaactccccc cggtcccgcg cgccgcgacc cggcggtgct
     3241 cagccggggc gcagctcgta gtgcggcagg ccgagcgcgg cgatctgctc gtcgaggctc
     3301 gtcacctcct cccgccaggc gcggtggtcg gccgacgagt gcgcggcggc gaactccgcg
     3361 cgcgtgccgg ccgtgcggac cacctggagg gcgaaggcgc gggcacccgc gtcgcgggcg
     3421 cgccgggcga tctcgacggc gtggcgggcg gcgggggagc cgggcgcgac ggtcgtgcgc
     3481 acctcgtggt cgacgcccga cgcgacgagc aggtcgaggc actcccacgc gaggtggccc
     3541 gcaccgggcc gccgcacgac gtcgtggtag tcctcgggca gcgccttgag gtccaggccc
     3601 acccagtcga cgtcgccgag cagcgcggcc agccgccgcg ggtagggccc cgcggtgtgg
     3661 agaccgacgg cgaacccgag cccgcgcacc tcgcggacgg cggggaggag cgcgccctgg
     3721 cgggtggcct ccccgccgga catgacgacg gcgtccagga ggcgtcgtcg tcggcggagg
     3781 aaggcgagca cgtcctccca ggggagcgtg ccgggggtgc gcggtgcgat gagcgccggg
     3841 ttgtggcagt aggagcagtc ccacgggcag ccctggcaga agaccgtcgc ggcgagccgc
     3901 ccgggccagt cgaccgtcga cagcggcgtc atcccggcga cctggaggtc gccggcacgg
     3961 gccggtgcgg gcgggtggcc cgccgcgacg gtgctcacgg cgccgcgacg ggggaggaga
     4021 cggcggcctg ctcggtgaac atctcccgct cggcgtactc gcccttcttg ccgatgttga
     4081 aggagctgac cggccggaag tagcccatga cgcgggtcca cacctcgcag gccaccggct
     4141 cctcgcggtc gacgccgcag cgcgggcagg tgtggtgctc accggcgagg tagccgtggt
     4201 tcgggcacac cgagaacgtc ggggtgatgg tgatgtaggg caggcggaag ctctccaggg
     4261 cccggcgcac gatctccttg cacgcctgcg ccgaggagat ccgctcgctc atgtacaggt
     4321 gcaggaccgt gccgccggtg tacttcccct gcagctcctc ctgccgctcg agggcctcga
     4381 aggggtcgtc ggtgaaaccg accggaagct gggaggagtt cgtgtagtac gggttggtct
     4441 cggtgccggc ctggaggatg ccggggaagc gcttgcggtc ctccttggcg aagcggtagg
     4501 tcgtgccctc cgccggcgtc gcctcgaggt tgtacaggtg cccggtggcc tcctggtact
     4561 cgaccatccg ctcgcgcacg tggtcgagga gacgggcgca cagtgcgtgc ccccgcgggt
     4621 cggtgaggtc gtactcgccg agggtgaagt tgcggaccat ctcgttcatg ccgttgacgc
     4681 cgatggtcga gaagtggttc tcgagcgtgc cgaggtagcg gcgggtccac gggaacaggc
     4741 cgccgtcgat gtgctcctgg atgacgacgc gcttgagctc gagggtgtcg cgggcgatgt
     4801 ccatgagctc gtcgaggcgg cggacgagcc cgggctcgtc gtgcgcgtgg aggtagccca
     4861 ggcgggccat gttgacggtg acgacgccga gcgatccggt ctgctccgcc gagccgaaca
     4921 gcccgttgcc gcgcttgagg agctcgcgca ggtcgagctg gagacggcag cacatcgagc
     4981 ggatcatgcc cgggtcgagg tcggagctga tgaagttctg gaagtagggc agcccgtact
     5041 tcgcggtcat cgcgaagagc cgctcggtgt tctccgcgtc ccagtcgaag tccttggtga
     5101 tgttgtacgt ggggatcggg aaggtgaaga cctgcccgtt cgcgtcgccc tcggtcatca
     5161 cctccatgta ggcgcggttg acgaggtcca tctcgtgctg gagctccccg taggtgaagt
     5221 cgcagggctc accgccgatg agcggcacct gctcgcgcag gtccggcggg caggtccagt
     5281 cgaaggtgag gttggtgaac ggggtctggg tgccccaccg ggaggggacg ttgaggttgt
     5341 acacgagctc ctgcacgcac tgcttgacct gcgggtaggt catgtcgtcc agccggacga
     5401 agggcgccat gtaggtgtcg aaggagctga aggcctgcgc gccggcccac tcgttctgga
     5461 gggtgccgag gaagttgacg atctgcccga cggcggagga gaagtggcgg gcgggtgcgg
     5521 cggagatggc accgggcacg ccgttgaagc cctcctcgag cagccgccgc agggaccagc
     5581 ccgcgcagta gccggcgagc atgtcgaggt cgtggatgtg gaggtcgccc tcgcggtggg
     5641 cgcggccagc gtcgggggcg tagacgcggt cgagccagta gttggcgacg accttccccg
     5701 aggtgttgag catcatcccg cccagcgagt agccctggtt ggcgttggcg ttcacccgcc
     5761 agtcgctgcg gtccaggtac tcctcgacgg tggtgatcgg gtcgacgtgg gtgggtcggt
     5821 ggtccatggg cttctcccga ggctcgtgcg gtccgtggca ggacagacgc tagagccggt
     5881 gcgtcaggga gtaaccacta ggtgttgggg cgtgtcgctt ctcgcgccac aagatgtggt
     5941 ggtcgaaccg gacgaatggt ggccggcgcg ggacctttgt cccggatccg ggagacgtca
     6001 gacgacggtg agggtgacgg tcgtgcccgg caccgcgagc tcgcccgcgt ccggcgacat
     6061 gctgcgcacg gtcccgaaga tcccgccgag cacccgctcg accttgacga cgaagcccgc
     6121 ggcctcgagc tcgtcggtgg cggcgcccac ctggcgaccg atgaggtcgg gcagctcgac
     6181 cggctgcggg ccgagggaga cggtgacggt cacctcgtcg ccccggtaga gctggacgtc
     6241 ctcacccggc tcggggctct ggctcacgac ccggccggcc gggacctcgg ggtggtagtc
     6301 ctcctcgacg acggcgctca ggccggcgtt ctcgaggtcg gacacggcgg tgtcggtgtc
     6361 ggcgccgacc accgagacga gctcgacggg ctcccgcccg gcggacacga cgaggtccac
     6421 gggctggtcg taggggatga cctccccggc ctcctggctc gcggacatca cctcgccctc
     6481 ggggacgtcg tcgtcgtacg gggtctcgac ctgcccgacg ccgagctggg cctcctcgag
     6541 cgcggcggcc gcctcgtcct gcgtgaggcc gacgagctcg gggacctcga ccatgaggat
     6601 gccgcgggag acgtggagga cgacggtgcc gtcggtgcgg acgcggtctc ccggggcggg
     6661 atcggcggag acgacctcgt tctcgggcac ggtgtcgtgg tgctcgcgct cgaccgtgag
     6721 gtcgatgcct gcctcgctga gcacggcgac ggcgtcgtcc tcggcgagac cgacgacctc
     6781 gggcacggtg acgtaggcgc cggggccctg ggtgaaccac caccacgagc cgccaccggc
     6841 gagggcgagc agggccagca ccatggtgag cgcgaagacc cggcgacgac ggcgacgacg
     6901 ggccggtccg gcgggtccgg ggtcgggggc gccggcgtgg atcgcgccga tgggcagggc
     6961 gacggtgccg gcgggcagcg gcgtcacgtc ggtggcggag ccgccggtcg cctcggcgtc
     7021 ctcctcctcg acggcggggg cgacgtccgc gcggcgggcg agggtggggt cgtcgagggt
     7081 ggcacgcgtg cggcgcagga gcgcgagggc ggcgtcggcg tcggcgggcc ggtcctcggc
     7141 gtcgcgcgcg gtgagggcgg cgacgagctc gtccacctcc gccgggagcc actcgacccg
     7201 ggaggagggc cgcggcacgc cgtcgttgac gtgctggaag gccacgcgga tcggctggtc
     7261 ggcgacgaag ggctgggagc cggtgatgag ctcgaagagg acgatcccga cggcgtagac
     7321 gtccgcgcgc gcgtcggcga ccccggaggt gacgatctcg ggggcgaggt acgcgacggt
     7381 gccgagcacg gtgccggtcg aggcggccgt ggcctcggtg acggcgcgcg cgagaccgaa
     7441 gtcggtgacc ttggggcgcc cgtcgcgctc caggaggacg ttctccggct tgacgtcgcg
     7501 gtggaccacg ccggcgcgat gggcgcaggc gagggcgtcg agcacaccgt cgacgacgtc
     7561 gagcgcgcgg ccgagtggca gggcgccctg ccggcgcagc tcggtgcgca ggttgtggcc
     7621 ctcgatgagc tccatcgtga ggtagctcgt gtcgtcggcc aggccctggt cgtagatcgc
     7681 gacgatcccg gggtggttga gccgggcggc cgaccgtgcc tcgcggcgga agcgggccac
     7741 gaagtccgcg ctctccgcga ggtgcgggtg catggccttg agggccacgg tgcggtccag
     7801 gcgccggtcc agcgcccggt agacggtggc catgccgccc cgtgcgatgc gggcacgcac
     7861 ctcgtaccgg ccgtcgacga gacggccgag catggggtcg ctcacggtgc gctgcacggg
     7921 gccgagtcta gagtggcggg cccgccccga ccggtaaggg gaccggtgag gcgggccgcg
     7981 tcgtcgtgct ccgtcagaac tgccgcatga ggttcttgat gcccgcgacg tagttgcggg
     8041 tgtcggcgta catgccgttg cgcttgaccc cggccaggcc ctggtagtag ccggcgaccg
     8101 cctggtcgaa gttgtcggcg gtgcggacca gctggcgcag gatcgcgacg ccggcgacga
     8161 cgttgtcctg cgggtcgagc aggttgagcc ggcggccgac gaggtccgag gcccactggc
     8221 ccgagctcgg gatgacctgc atgacgccga cggcgttcgc aggggagacg gcgcgcatgt
     8281 cgaagccgga ctcctgctgg gcgatggcca gggccagcgc cgggtccacg cccatggtca
     8341 ccgcggtgct gcggaccatg gcgcgcatct ggtcgcggga ggggacgctc atcgacagca
     8401 gcgtcgcctt gttcgtgttg gccgcgccga cgacgtcgct cgcgtaggtg cgcccgagga
     8461 aggtgctgcc gacgagctgg ccgccgctcg tgctgccgcc acccgcgctc gtgccaccac
     8521 cggagccgcc gggcacggtg agacgctggc cgacgtagat gagcccggag ccgggaaggt
     8581 tgttggcgga gatgatcgcc gacgtcgtcg agccgtagcg cgaggcgagg cccgagacgg
     8641 tgtccccggc cgcgaccacg tgggtgcggg aggcggtgct gctcaccggg accgtcgccg
     8701 gcttggcggc gggcttggcg gcgggggctg agcccgagcc gccgcccgag acggtgaggc
     8761 gctggccgat gcggatgagg ccggggtcgc tcaggccgtt ggcggaggcg atgcgctcga
     8821 ccgtggtgcc gtagcgctgg gcgatgccgg agacggtgtc cccggcgcgg accacgtggg
     8881 tgctcgcgct ctgggcggcc gggcggttcg ccgcgggggc ggcgctcacg ccgctggcgg
     8941 aggcgccggg gatggtgagg cgctggccga tgatgatgag cgcgcgcgag ccgagacggt
     9001 tggcggagac gatctcctcg accgtgctgc cgtaccgctt ggcgagcgcc gagacggtgt
     9061 cacccgcggc gaccgtgtgc gtggtggagc tggcggcgcg ggtgggggcg gcggtcgcgg
     9121 ccttgccggc ggccggcagg cgcagcacct gtcccacctt gatgagggcc cgggagttga
     9181 ggttgttcgc cgagacgatc gcggagacgg tcgtgcccgc gcgggcggcg atcgtgctga
     9241 cggtgtcccc ggcgcggacc tggtaggtgc ccgtcggcag gctgcgctgg gtggcgggcg
     9301 cggtgagcgc gagcgccgtg gcgcccacgg tgggcgcggc gggggccgcg gtggcggcgc
     9361 cggccggcac ggtcatcgcc gcgacggtgg tcgccgcgag cacgaggccc acgccggtgc
     9421 ggccggcggg gcggggcgcc cgggtgcgag tgcgagcctt catcgatgtc ctccgcgacg
     9481 ggtcccggcg tgtcgcagac gggaccacag tggctggtgt tattggtggg gcgagagtga
     9541 acgctgtgac actagcgtta tcgaggcggc acgtaaaggc ggggacggca ggggccgccg
     9601 ggctcgttag gctgccggga tgaccgactc agacccccgc tggtgctccc tgcccgaggt
     9661 cgccgagctc ctcgatgtgc ggctgcgcga cgtccgggac ctcctgcgcg accaccacct
     9721 ggccggcacc cgcccgcagg aggaggggcc cttcctcgtc ccgcgcgact tcatcgtcac
     9781 cgcggaggac ggcgccgcgg agccggggcc ggtgccctcg ctgcgcggca cgctcaccct
     9841 gctcaccgac accggcttca cggtcgacga ggccgtggag tggctgctca gcgagcagga
     9901 ggagctgggc accacgccga tcgccgcgct ccgggcgcag cggatccacg aggtgcgccg
     9961 gctcgcccag accttcgcgg tctgaggggc gggcggcggc tcaggccgcg cgggcggtga
    10021 gccggcgcgc cagcccggtg agcatctcgt ggctcgcggc gggcaggccg agcgtgtcca
    10081 gcgcggccag gccctcgtcg aggtggctgt cgacgagccg ctggtgctcc tcgacggcgc
    10141 cggtcgtctc caggacggtg cgcagcagcg cgacgtcgtc cgcggacagg tccgggcggc
    10201 ccacgtgccg ctgcagggtg gcgcgctgct cggcgtccgc gccccgcagc gccagggcga
    10261 ggagcacggt gcgcttgccc tcgcgcaggt cgtcaccggc gggcttgccg gtgacctcgg
    10321 gctcgccgaa gacgccgagg acgtcgtccc acagctggaa ggccaccccg agggggaggc
    10381 ccacccggcg cagcgcggcg agggcctcgt ccggcgcgcc ggcgagggcg gcgccgagga
    10441 cgagcgggtg ctcgacgctg tagcgcgccg acttgtgctg cacgaccgtg agcgcgcggt
    10501 cgacgtcgtc ctgctcgttc cacggcagca cctgggagcg cacgtcgagg tactgcccca
    10561 cggccacctc ggtcgtcatg aggtcccagg tggctcgcgc ccgcgtggag gcggcgtcgt
    10621 cgacgagccg ccgcgcgagg tccatctcga cggaggacac cgacaggagc aggtcgccga
    10681 ggaggatggc gccggcggcc ccgtgccggt ccgggtcgcc cagccagccc cgctcggcgt
    10741 gctcgcccgc catccgccgg tggacggccg gcaggccgcg gcgcgtcagc gacccgtcca
    10801 tgaggtcgtc gtgggcgagt gcggcgccct ggaagagctc gagggcgctg cccgcgagga
    10861 cgggcgccga gccggccgtc accggccggt cggtgaaggc agtccagccg gcggtgcaga
    10921 aggccgcgcg cagccgcttg cccccgccga gcagggcctc accggcggac agcagctcct
    10981 ccaccccctc gagggactcg aaggggcggg tgtgctcgcg cagggcggtg gcgacacggt
    11041 cggtcacgag cgtggccagg ccggcggtgg gtgctgccat gcagggcagc ctacgggtgg
    11101 tggccgctgc tccccaggcg agcaggcccg ggtgtcctcc acaacgggcg cctgcgcccc
    11161 ggtggtggac acccgcggcg gtgtgcgatg ggcccatgaa cacgacgacc atcacgatct
    11221 cccagcccga ggacatcgtc gcctacctgc cctaccggct cggcttccgc ccgcgggact
    11281 cggtggtcct gctcgcgatg tgcggggagc gcaaccgcct gggactcgtc acccgggccg
    11341 atctcgcgga catcggtcac ccgcgggtgg gacccgccct cgtccgcgac gtctcccggc
    11401 tcatggcgga ggagggggcc cacgacgtct tcgtcgtcct ctactccgac ctgccccggg
    11461 accggctcgc ggccgaccct ctcgtgcgtg gcgccctgga gcacctgcgc accctcacct
    11521 cgtgggcgga cccacccggc ccctgggtgg tgggcgccgg cacctacggg tgctggggga
    11581 ccggcgagga gtgcgccccc gccacccgcg acgccgccga gctcgaccag cggcccgtcg
    11641 tcgccaccct cgtcctccac ggcctcgccc tcgtccccgc gcgggaggac ctcgcggtgc
    11701 cccgcaccac cgacgccgag cgtcgacggg ccgccacgcg tgcgacgcgg gagggccgcc
    11761 gccggctcgc ggagctgcgc gcccgcagcg gcgggggagc ggcgctgccc ggtgcggcct
    11821 tcggtgtccc gggtgcggcg ccggccgtcg accagcggga ggtgaccgag tggcgggagg
    11881 aggagcggcg ccgctgggag cggctcgtgg ccctcgccgt acgcggcgcc gtcctgccgg
    11941 cgagcgagct cggcatgctc gcggccgccc tggaggacaa caccgtgcgc gacagcgtcc
    12001 tgtgctcggt gatccacccg ctggccggcc gcgtgctcga ccgggcccgg accgaggaga
    12061 tcctcgacct cgcgatgctc cccggtgggc ccccgccgga ccaggacagg gtggagcccg
    12121 ccgccgccgt cctgcgggcg ctcgtggcct gcgtgccacg ccgctcgggg gcactggcgc
    12181 tcggcctgct cgcctgggtc gcgtggtggt gcgccgacgg cgcccgcgcc gacgtcctcg
    12241 cccagcaggc gctgcgtgcg cggccgcgca cccgcctggc cgagctcgtc gacgaggccc
    12301 tcgcggcgcg cctcccgccg gggtgggtcc ggaccgcctc gggtgacccg gcggccccga
    12361 gcccgccgat ccggtagcgt cagcccacac ggagcaggcc caggacgtcc cggcgcgagc
    12421 cggaggatgg agtgctgaat gacggtcgtc gtgggctacc tcgcaacccc ggagggcgag
    12481 gcggcgctgg agaccggcgt cgcggaggcc cgacgacggg acgcacgcgt cgtcgtcgtc
    12541 atctcccggc gctcccggca ggagcagcac gccgacgtcg acgccgagct cgacgccctg
    12601 cgtgaccgac tggacgacgc cgacgtcgcc tacgacgtgc gccagctcgg ccgcggcaac
    12661 gacgtcgcct ccgacctcgt cgagaccgcc gaggagacgg gggccgagct catcgtcatc
    12721 gggctgcgcc gccgttcgcc ggtgggcaag ctcatcctcg gctccaacgc ccagcgcatc
    12781 ctcctcgacg cgccgtgccc ggtgctcgcg gtcaagccgc cctccacgga gcgccgctcc
    12841 tactgagttt ccgccaccgg ccggggaatg ccgggggcgc ctgccgtgtt gacacgggtg
    12901 gctgccgatg gactggcgtc cgcgtgagac cgcgcggacg ggcatggcga gttataattg
    12961 taggcagcgc accggctcga agccggaacc cccattcccc tccgaaaggc tttctgtgtc
    13021 gtcgcacgcc cagagcacct ccagccgcac gcacgccgcg cgcacctctg ccggcggcac
    13081 caccgcgtcg gtcgaggaga cgtcgacgaa gacccgggcc aaggcgcccg cgaagtcgac
    13141 cacggccaag aagcccgcgg cgaagaagga gaccagcacg gctaccaagc gcacggccac
    13201 gaagaccacc gccgccaaga aggcggccct caaggcggtc cccgacgtcg aggagaccac
    13261 ggcgaccact ggcgaggcga gcgagaccgc cgccgcgccg gaggccgagg ccaccaccgg
    13321 caaggagagc gggttcgtcg tctccgacaa cgacgacgac gacgccccgg tccagcaggt
    13381 cgtcaccgcc ggcgccaccg ccgacccggt caaggactac ctcaagcaga tcggcaaggt
    13441 cgccctcctc aacgccgagc aggaggtcga gctcgccaag cgcatcgagg ccggcctgtt
    13501 cgccgaggag aagctcgcca gcgaggacgt ctccggcaag ctcaagcgtg agctcgagtg
    13561 gatcgccaac gacggccgcc tcgccaagaa ccacctcctc gaggccaacc tccgcctcgt
    13621 cgtctccctc gccaagcgct acaccgggcg cgggatgctc ttcctggacc tcatccagga
    13681 gggcaacctc ggcctcattc gcgccgtgga gaagttcgac tacaccaagg gctacaagtt
    13741 ctcgacgtac gccacctggt ggatccgtca ggcgatcacc cgcgccatgg ccgaccaggc
    13801 ccgcaccatc cgcatccccg tgcacatggt cgaggtcatc aacaagctgg cccgcgtcca
    13861 gcgccagatg ctccaggacc tgggccgcga gcccaccccg gaggagctgg ccaaggagct
    13921 ggacatgacg cccgagaagg tcgtcgaggt ccagaagtac ggccgtgagc cgatctccct
    13981 gcacaccccc ctcggtgagg acggtgacag cgagttcggt gacctcatcg aggactccga
    14041 ggccgtcgtc ccggccgacg ccgtgagctt caccctcctc caggagcagc tccaccaggt
    14101 gctcgacacg ctctccgagc gcgaggccgg cgtcgtgtcc atgcgcttcg gcctcaccga
    14161 cggccagccg aagaccctgg acgagatcgg caaggtctac ggcgtcaccc gtgagcgcat
    14221 ccgtcagatc gagagcaaga cgatgtccaa gctccgtcac cccagccgct cgcaggtcct
    14281 gcgcgactac ctggactgag cgcacgcgta cgacgaaggc ccgcaccggc acggtgcggg
    14341 ccttcggccg tcctagccgc gtgccgcgtg gcggtcggcg ttggcgtgga tggcgtcgcg
    14401 gacgtactgc gccagcccgg gacggatgtc ctcgtaggtc ttcgtgaagc gcgggtcgct
    14461 cacgtacatg tccccgaggt tgcggtggaa gtccgccgag agcgagtaga agcgctcgtg
    14521 gatgtggagc cgggcccgct cggcggcgtc catggcggct tcgctcgtcg cgggctcacc
    14581 cgcctccagg gcggcgacga aggcggcgtt gacctcctcg gcctccgcct tgatctcctc
    14641 ccagtcggcc ttggtgtagc gggacgtgcg ctgctgggac tggcgccacg cgtcggtgtc
    14701 gccccagcgg tccttcgcct cggcggcgta ctcgtcgctg aacccgtcgc cgaacagctc
    14761 gcgctgctcc tccttggtga ggttcacccc ggtcatctct ttctccagtg ctcggtcgat
    14821 ggccgtgacg agctcggcga gctcctccag ccgggacacg accgcggaac gctgccgtcg
    14881 caggtgctcg agcagggccg gccgcgtgcc gtcgtcgagc agctgggcga tctcctccag
    14941 ggagaagtcc agccgccggt agacgacgac gtgctgcagg cgggtgacgt cctcctcggt
    15001 gtagagccgg tagccggcct ggctgcgggc gctcgggctc agcaggccga tcgcgtcgta
    15061 gtggtgcagc gtgcgcaccg tgacgccgaa gcgctcggcc acctggccca ccgtcagcac
    15121 cgtgaggact cctgttccgt cggtcatgcc tccaccgtgg cgcctgacgc cgcgtgaggg
    15181 tcaagcccat cctcccggac cgcggggctg cgcgtgcggg atgtgggccc ggaccgcccg
    15241 gcaggtccgg ctgcggacga ggggggggcg cggccgacct ctacgatcga ccggtgagca
    15301 ccgacacctc gaccacgcgc cggccgctgg gcctgcgcac ctccgacctc gtgaccgccg
    15361 ccgccaccgg gctcctcacg ctgccggacc cggcccgccg caccccggcc acccgcttcg
    15421 cgctgcggac cgccgtcgcc gggaccaccg gcgccggcgt gtggctgggc acggacgggg
    15481 actccgccct cgacctgccc agccgggccg cgttcaccgc cggcgccgtc gggctcgtct
    15541 acggggccgc cgagctcggc gaggccatgg accgggcgct ccagcgccgg ctcgtgcgca
    15601 tgggggtgcg ccgcccgcgg ctggcgatgg ccctggccgg cgtcggcgcc tcgctggccg
    15661 tctccttcct cgagcggcgg gccgaggcca ccgacgagga ggacgacgcc cccgagggtc
    15721 ccgtcctgcg tcccctcccg gagcccgtgc gcgagctcgt cggcgcgatc ctcgcgcaca
    15781 ccgaggacta cgactccctg cgcctgcgcg cccagctcgc cggtgcccgc gaggaggtct
    15841 ggggcgagcc ggaggacgcc ccgcagatgg tcgagctgtc cgtgcccgag ggcgccccgc
    15901 tcgccgtgcc gcactccttc accttcccgg taagtgcgcg cttcacctcc gcgcgcgggg
    15961 tgccctgtgc cgcgcgtgtc ctcgtcagcg gcggccggct cgccgccgtc gtcgtcgacc
    16021 tcgacgacga cgcgtgggag gtgctcgccg aggactggga ccctgccggc ggcgaccccg
    16081 acccgctcgc ggacgtgacg ctgccgcggg cgcaggacgt catcctggtg accgaggcgc
    16141 ggggctgagc ctcacacgtc cttgccgtag gcgagggacc ggcgcgactc gcggtagccg
    16201 aggcccgtgt agaggtccag ggcccggttc gggttctcga cgtcgacgcc gaggtcggcc
    16261 cgctcgatcc cgtcctcccg cagggcccgc atggtcgccg ccaggagggc gctggccacg
    16321 cccgcgcgcc gccacggccg ccggacaccg aggaggtcgg tccacccggc cgagtagccc
    16381 tgcgccgccc agtcctgctc gtaggcggag gtgaggctgt acccggcgac ctggtcgccg
    16441 tcgaggacga cgaagctcca cgaggggcgg aagtagcgcc cgccgacgct ctggcgctcc
    16501 cagttctccg ggtcgcgggg ctcgctgccc cagtggtcgg cgaaggcctc gttgtgggcc
    16561 agccggaccg gctcgctgag gcccgggtcg tagggcacga gccgcaggcc ctcccgcagg
    16621 gcgggcgcgg cgatctcggc gtccagcggg cgggtgagct cgaggtagac gcgcagccgc
    16681 cggaacccgg cccggtccag gaggcgctcg gtggcggtga gcccgtcgtc gacgttgacg
    16741 agcacgcgtc ccggtccggt ggaccgtgcg gcggcgatct tctcccgccc cagccgctcc
    16801 tgccaggcga gcagctcgcg gccgatcccg cggccgcgcc acagcgggtg caccccgccc
    16861 cagcagaagg cacggaccgt gcgcacgtca cccgggagca cctggacgtg cccgaaggcg
    16921 cgcgggacgc cgtcgtcgtc gatgccgatg gtgctgtcgc gggccgggtc cttccacgag
    16981 ccgtcgagca gctcgtcgtg gaggtcctcg ggggtgtagc gctcggcggg gtcgtcggcc
    17041 gcctcgatcg cccggacgag cccgtgccag tcggggacgt cctgcggggt gatgggccgc
    17101 cagcgcaggc cggagacggg ggcgggtgcg gtgctcatgc cgcggagatt acggggcgcg
    17161 ccgccggccg tcatgggaaa tagcgcaggc gccgacaccc atcgggtgcc ggcgcctgcg
    17221 gtctgtcgtg gagggcgcct ctcagcgggc gttgtcctcg gtgagacggt gcgtctcgtc
    17281 ctggatggcc gtggcgaccc cttcgagtgc ctcggcgtgc ttgcgggcgt ggtgcgcgca
    17341 gaagagcagc tcccctacgg gcagtcccac gcgcacatac gcctgggcgc cgcagcggtc
    17401 gcagcggtcc tgtgcggtca gcggggcggt catcgttgcg ttcacacctg catacaacca
    17461 cgtcggcgcc ggaaacatcc ccgggacggc accccgttcg cttccagcgg accgggtggc
    17521 gggatccggt gaccagggtc acgacgacgg ccggcgcgcg ggtgctcccc atcacctcct
    17581 cacggggtcg tcttgcgcga ttccgcgggt cagtccgcgg gagcggggca agtcgttcgt
    17641 atgatcgccg ggtgcctccc aagtcgaccg cgtcgccctc gcagtacacc gcccgtcacc
    17701 tctccgtcct cgaggggctg gaggcggtcc gcaagcgccc gggcatgtac atcggctcga
    17761 ccgactcgcg cggcctcatg cactgcctgt gggaggtcat agacaacgcg gtcgacgagg
    17821 ccctcgaggg ccacggcgac gccatcgccg tcgttctcca ccccgacggc tccgtggagg
    17881 tccgcgacaa cggccgcggc atccccgtcg acaccgtcga ctccgtgggc ctgagcggcg
    17941 tcgaggtcgt cttcaccaag ctgcacgcag gcggcaagtt cggcggcagc tcctacgccg
    18001 cctcgggcgg cctgcacggc gtcggcgcct ccgtcgtcaa cgccctgtcc gcgcgcctgg
    18061 acgtcgaggt cgaccgcggc ggcaagacct accggatgac cttccaccgc ggcgagccgg
    18121 gcacctacga cgaccgcggc ggcgccggcc ccgaggcgcc gttcgcgccc ttcaccgacg
    18181 cgagcgagct cgccgtcgtc ggcaagacgc cgcgcgggcg caccggcacc cgcgtgcgct
    18241 actgggccga cccgcagatc ttcccctcga cctcccagtt ctcctacgac gagctcgtca
    18301 cccgcgcccg ccagacgacc ttcctcgtcc cgggcctgac gatcaccgtc cgcgacgagc
    18361 gccgcctgcc cggcacgccg ggggaggacg gcccggtcga ggaggtcttc cggcacgacg
    18421 gcggcgtcgt cgacttcgcg gagttcctcg ccaccgaccc gcccgtctcg gacatctggc
    18481 gcctcaccgg cagcggcacc ttcaccgaga cggtccagca gctcgacgcc tccggccacc
    18541 tgcggccgca ggaggtcgag cgcacctgcg aggtcgacat cgcgctgcgg tgggggcagg
    18601 gctacgagac gacggcccgc tccttcgtca acatcatctc cacgcccaag ggcggcagcc
    18661 acctcaccgg cttcgagcag gggctcgtgc gcacggtgcg caagcagatc gaggcgaact
    18721 cccggcgtct caaggtcacc gccaaggacc cgaagatcga gaaggacgac gtcctcgccg
    18781 gcctcaccgc cgtcgtcaac gtccgcctgc ccgagccgca gttcgagggc cagaccaagg
    18841 agatcctcgg cacggcgccg gtgcgcggca tcgtcgcgaa cgtcgtcgac aagcagctca
    18901 ccgagatcct cacctcgccc aagcgccacg agaaggcgca ggcttccgcg gtgctcgaga
    18961 aggtcgtggg ggagatgcgc gcccgcgtgc aggcgcggct gaccaaggag atctcgcggc
    19021 gcaagaacgc gctggagagc tcacggctgc ccgccaagct cgcggactgc cgcaccgacg
    19081 acgtcgagcg ctccgagctg ttcatcgtcg agggcgacag cgccctcggc acggcgaagc
    19141 tcgcgcggtc cagcgacttc caggcgctgc tgccgatccg cgggaagatc ctcaacgtcc
    19201 agaaggcctc acccgccgac atcctccgca acgcggaggt cgcctcgatc atccaggtca
    19261 tcggcgccgg atccgggcgc accttcgacc tcgacgccgc ccgctacggc aaggtcatcc
    19321 tcatgaccga cgccgacgtc gacggcgccc acatccgcac cctcctcctc acgctgttct
    19381 tccggtacat gcgcccgctc gtcgaggccg gccgcgtgta cgccgcggtg ccgccgctcc
    19441 accgcgtgga gatcgcgggc tcgggcggca agaagggcga gaagatctac acctactccg
    19501 agagcgagct ccaccagctg ctgcgcaagc tggagaagca gggcaagcgg tacaaggagc
    19561 cgatccagcg ctacaagggc ctgggggaga tggacgccga ccagctcgcc gagacgacga
    19621 tggaccccgc ccaccgcacc ctgcggcggg tgagcatggc cgacgcccag gcgctggccg
    19681 aggccgagcg ggtcttcgag ctcctcatgg gcaacgacgt cgcccctcgc aaggacttca
    19741 tcgtcgccgg tgccggccag atcgaccggg accgcatcga cgcgtgacgc gccccgcacc
    19801 gaccaccatc gccagcgcac tttaggattc cgacatgccc gacaccctcc ccgaccgcgc
    19861 cgcccctccc gcccacgccg ccgtgcccgc cccacacctc ggcctcacct ggcgggcgct
    19921 caccaccgac gacgtcgacc acgtccatgc gctcatcggg cgctgcgagg ccgtggacca
    19981 gcccgtcctg cgcacggcgc gcgcccaggt ggaggacgtc ctcgggcgcc cggccaccgg
    20041 gatgaaggcc gacagcctgg gcggcttcga cagctccggg gagctgcgcg ccgcagcctt
    20101 cgtccacgcg ccgctcgggg acgagaccca cgcccgcgtg ttcatctccg cgtcggtcga
    20161 cccgtcgtgg cgcggacgcg gcatcggccg cgccctgctc acctggcagg acgaccgtgc
    20221 ccgccagatc ctcgccacgc tcgacccgag cctgcccggg cgcatcgccg cctacgtcga
    20281 cgaggacctc gaggaccgcc gtcgcctgta cgccgcggcg ggcttcagcc ccaagcgcac
    20341 cttccgggag atgcgcctgc ggctcaccga gccgcccgcc gtcgtcgacg tccccgaggg
    20401 ctacgagatc cggcagtgga gcccggagat cgacgacgcc gtccgcgacg cccacaacga
    20461 ggccttccgg gaccactggg gctcccagcc cgtcgccgag accacctggg cggcctccca
    20521 ccgttcgctc gaggcggcgt ggagcgtcgt cgccgtccac ctcgagaccg gcagcgtcgc
    20581 gggctacgcg ctcactgccc gccacgagca ccagtgggag gcgctgggcc acaccgaggg
    20641 ctacaccgag ctcctcgggg tgctgcgcgc gcaccgcggc tccggggtgg cgcgcgcgct
    20701 gctctccgcg gtcctcggtg cgctgtaccg cgacggcatc gaggtcgcgg cgctcgacgt
    20761 cgacatggag aacccctccg gcgcccaccg cttttacgag cgcatgggct acgagccgca
    20821 gggcgcccgg atcctctaca cgatcgaggt gtgacgcgtc ccgctcagcg gtgccgccgg
    20881 taggccgcgg cgcggtgagc acgtatcgtc ggagcatgct cgaggactac gacggcgccg
    20941 gccgcgcccc ggcgccccgc gccgccgtgg aggggaccgg cgtcgagctg ccgcacgggc
    21001 acgacctgcg gtggcactgg ctgaccctgg agagcaacga cgcgctcgtc gagctgctcg
    21061 ggcgcatcga ggagcacgac
//
