LOCUS       NZ_JACSPZ010000014     23039 bp    DNA     linear   CON 20-NOV-2024
DEFINITION  Solibacillus faecavium strain A46
            NODE_14_length_50243_cov_498.799047, whole genome shotgun sequence.
ACCESSION   NZ_JACSPZ010000014
VERSION     NZ_JACSPZ010000014.1
KEYWORDS    WGS; RefSeq.
SOURCE      Solibacillus faecavium
  ORGANISM  Solibacillus faecavium
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Caryophanaceae;
            Solibacillus.
REFERENCE   1  (bases 1 to 50243)
  AUTHORS   Gilroy,R., Ravi,A., Getino,M., Pursley,I., Horton,D.L.,
            Alikhan,N.-F., Baker,D., Gharbi,K., Hall,N., Watson,M.,
            Adriaenssens,E.M., Foster-Nyarko,E., Jarju,S., Secka,A., Antonio,M.,
            Oren,A., Chaudhuri,R., La Ragione,R.M., Hildebrand,F. and
            Pallen,M.J.
  TITLE     A Genomic Blueprint of the Chicken Gut Microbiome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 50243)
  AUTHORS   Gilroy,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-AUG-2020) Microbes in the Food Chain, Quadram
            Institute BioScience, Norwich Research Park, Norwich NR4 7UQ, United
            Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.1
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 160x
            Sequencing Technology             :: Illumina NextSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014836905.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 02:01:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,850
            CDSs (total)                      :: 3,809
            Genes (coding)                    :: 3,795
            CDSs (with protein)               :: 3,795
            Genes (RNA)                       :: 41
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 14
            CDSs (without protein)            :: 14
            Pseudo Genes (ambiguous residues) :: 0 of 14
            Pseudo Genes (frameshifted)       :: 3 of 14
            Pseudo Genes (incomplete)         :: 10 of 14
            Pseudo Genes (internal stop)      :: 2 of 14
            Pseudo Genes (multiple problems)  :: 1 of 14
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:04:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 12266
            Orig. end                         :: 35305
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JACSPZ010000014.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23039
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23039
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23039
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13039](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13039
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            655..1530
                     /locus_tag="H9635_RS18350"
                     /old_locus_tag="H9635_18320"
     CDS             655..1530
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR01716"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /locus_tag="H9635_RS18350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_18320"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_191701766.1"
                     /sec_met_domain="TIGR01716 (E-value: 2.1e-27, bitscore:
                     87.8, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQIGVIIKKLRIDKKIQSNTLYQNLLSRPAIAKFESGESDTTVVK
                     FMIILDRLNISLEEFEVAYRMNSTKNIMEIYSPGAYKKAFYARDVPELYYLSRMSMQKY
                     EKTKLVKYQHNSAVINLLISVIENTSDIMEDRELLQNYLSKCEYWSYYEITLFTNTLSF
                     YSNEFIDVTYKHVKRVLISYQGLVRYKNELALLLFNILQLKITTNQFTSLNYYLNELIV
                     LKDECIDNMYVQTIICFFTLLMEVIKGNKNNIAELYKIIDIFEYLEMQFKADQCRKLLT
                     HVINHSSIKT"
     CDS             complement(1683..1829)
                     /gene="allorf_13949_14095"
                     /locus_tag="allorf_13949_14095"
                     /protein_id="allorf_13949_14095"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MQNKGHPVIAGRSSRKPLDELTSTVTRRRQPFRRITITSCPKHKK
                     LSK"
     CDS_motif       complement(1797..1829)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MQNKGHPVIAG"
                     /locus_tag="allorf_13949_14095_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(1683..1796)
                     /prepeptide="core"
                     /locus_tag="allorf_13949_14095_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.80"
                     /molecular_weight="4228.9"
                     /monoisotopic_mass="4226.5"
                     /core_sequence="RSSRKPLDELTSTVTRRRQPFRRITITSCPKHKKLSK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MQNKGHPVIAG"
                     /leader_location="[1796:1829](-)"
                     /alternative_weights="4247.0"
                     /alternative_weights="4265.0"
                     /alternative_weights="4283.0"
                     /alternative_weights="4301.0"
                     /alternative_weights="4319.0"
                     /alternative_weights="4337.1"
                     /alternative_weights="4355.1"
                     /alternative_weights="4373.1"
                     /alternative_weights="4391.1"
     CDS             1687..1842
                     /gene="allorf_13953_14108"
                     /locus_tag="allorf_13953_14108"
                     /protein_id="allorf_13953_14108"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MDNFLCLGHDVIVMRRNGCLRRVTVLVSSSSGFLDDLPAITGCPL
                     FCTVYS"
     CDS_motif       1687..1770
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MDNFLCLGHDVIVMRRNGCLRRVTVLVS"
                     /locus_tag="allorf_13953_14108_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       1771..1842
                     /prepeptide="core"
                     /locus_tag="allorf_13953_14108_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.70"
                     /molecular_weight="2285.6"
                     /monoisotopic_mass="2284.1"
                     /core_sequence="SSSGFLDDLPAITGCPLFCTVYS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDNFLCLGHDVIVMRRNGCLRRVTVLVS"
                     /leader_location="[1686:1770](+)"
                     /alternative_weights="2303.6"
                     /alternative_weights="2321.6"
                     /alternative_weights="2339.6"
                     /alternative_weights="2357.6"
     CDS             complement(1876..1995)
                     /gene="allorf_14142_14261"
                     /locus_tag="allorf_14142_14261"
                     /protein_id="allorf_14142_14261"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MEALLGEEGGPIQHESLRLFVLNCQLVFVVCSSISNSPP"
     CDS_motif       complement(1966..1995)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MEALLGEEGG"
                     /locus_tag="allorf_14142_14261_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(1876..1965)
                     /prepeptide="core"
                     /locus_tag="allorf_14142_14261_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.00"
                     /molecular_weight="3137.7"
                     /monoisotopic_mass="3135.7"
                     /core_sequence="PIQHESLRLFVLNCQLVFVVCSSISNSPP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MEALLGEEGG"
                     /leader_location="[1965:1995](-)"
                     /alternative_weights="3155.7"
                     /alternative_weights="3173.7"
                     /alternative_weights="3191.7"
     gene            complement(2842..3183)
                     /locus_tag="H9635_RS18355"
                     /old_locus_tag="H9635_18325"
     CDS             complement(2842..3183)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020438.5"
                     /locus_tag="H9635_RS18355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_18325"
                     /product="YolD-like family protein"
                     /protein_id="WP_191701767.1"
                     /transl_table=11
                     /translation="MDNKNRDRGTIKWTAMMMPEHVKLIREWYDEDNFVLEPQLDEFDY
                     EELAHQIQTAVQTHSVVLIHYWNSGESFTIEGTIKKLPVNAAFITTLSPQGDKRIYIPH
                     IMKIHLYEA"
     misc_feature    complement(3202..3216)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.75"
                     /tool="antismash"
     misc_feature    complement(3203..3216)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: strong, score: 23.96"
                     /tool="antismash"
     gene            complement(3295..4176)
                     /locus_tag="H9635_RS18360"
                     /old_locus_tag="H9635_18330"
     CDS             complement(3295..4176)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H9635_RS18360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H9635_18330"
                     /product="hypothetical protein"
                     /protein_id="WP_191701768.1"
                     /transl_table=11
                     /translation="MADKTFGVKVSEEMYEKAKMVIESSGVSSKDWFEKAVALYELNTI
                     KQGSSDYTQDLSELEHHTTRMYELIVNMIQRSVYLKDHAVKDISDKLESKEAIIQEFQQ
                     QLFQLKEEITLKNNMVTALQEQEKELKEKLKANETTLENNQALIAEYKEKNDTLSGLVA
                     KYQAYAEENEQLKIDFSNEKAALVEQANAAEVKGNALQQELAESRKTLASEQKKFEDTL
                     QLSIERKDLEREKALVELERQQQAQLAKANEQYNEQIQALYAEIAELRKINDESREKYQ
                     AEIEALKVQKEK"
     gene            complement(4320..5264)
                     /locus_tag="H9635_RS18365"
                     /old_locus_tag="H9635_18335"
     CDS             complement(4320..5264)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014822312.1"
                     /locus_tag="H9635_RS18365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_18335"
                     /product="DNA primase"
                     /protein_id="WP_191701769.1"
                     /transl_table=11
                     /translation="MEQVIPIEQRIKEVLANDTLFQVIQGTPNEQHFLSEPYLLELIEK
                     KYYSTPEVASWFDVTDAQLRYYIKPFEEYLFDDQATNPTTATLIRLDFKAILKLRMILL
                     LKDEYRVRGLRQLLRINEDGHIIQKRPSPSTEIATPDDIEYKLNAMSQALEQIMKTGLF
                     KMEQNEETQQMQLTINQDFLEQKIKAIPLETSQKLEKIQTITKNLEQENTELRKMVEGM
                     MASNKEDIAIRIREKSIEQTVLNRLQNEAVQQYTQQKKPLFQKLFRSAQIEIDKKRYIS
                     AYIEEHYSKQLTLALHEYHKQSLEYDDQQNVPS"
     gene            5905..6423
                     /locus_tag="H9635_RS18370"
                     /old_locus_tag="H9635_18340"
     CDS             5905..6423
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H9635_RS18370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H9635_18340"
                     /product="hypothetical protein"
                     /protein_id="WP_191701770.1"
                     /transl_table=11
                     /translation="MNKKESIKGWEFISSTPDLYTFELDDKVFYSGRKSGLLNAKIGVS
                     TREFATIVQRFQASIYLGKQIKMSCYLKAERETKCQVWLQINDSYDDIIIFNSMDNSIF
                     QGKTDWNYYSIILDVPKESACILFGMQLFGAGKVWVDNFKFEEVSEIISRTNNADRNLS
                     EQPINLDFN"
     gene            complement(6670..7851)
                     /locus_tag="H9635_RS18375"
                     /old_locus_tag="H9635_18345"
     CDS             complement(6670..7851)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016150.5"
                     /locus_tag="H9635_RS18375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_18345"
                     /product="DUF418 domain-containing protein"
                     /protein_id="WP_191701771.1"
                     /transl_table=11
                     /translation="MQKKRIDQLDALRGISLLGILLVNMLIFQYGILGKDQLIYFTDSN
                     TDIWTRNLIYILIEGSFLPIFTFLLGYSLVLYRRSSNTIRPSKIILKRSIGLLLIGFLH
                     FLFIWEGDILFSYGLTTLFLLMFIKRKPHTILIWALIFLGTISLFSYGSYNQSALDPNK
                     ISSYILNTEEVYSNGHYSEILQHRLESEALTKVLGLDIEGMGTFILILTTLVSPFTLLP
                     MALLGIYAAKMKFYKINPRYYYIGILLIPIGIVMKLLYLQYPNNDLYGMTFTLGSNFLG
                     IGYISLLFSIYPYLKLINPYLIATGRLSLSNYIAYSIIFTFIFYGYGLGLFGKIGVLNG
                     VIITFVVYVFLAILSKLYLKKWDNGPMEILLKKFINIGEKRKFESELSTKTSS"
     gene            complement(7947..8150)
                     /locus_tag="H9635_RS18380"
                     /old_locus_tag="H9635_18350"
     CDS             complement(7947..8150)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892393.1"
                     /locus_tag="H9635_RS18380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_18350"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_191701772.1"
                     /transl_table=11
                     /translation="MLDNQISIWRAHKKMTQEQLAKEVGVTRQTIVALEKNRYNPSLDL
                     AFRISKALGKQIEEVFIHIGDE"
     gene            complement(8201..8491)
                     /locus_tag="H9635_RS18385"
                     /old_locus_tag="H9635_18355"
     CDS             complement(8201..8491)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H9635_RS18385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H9635_18355"
                     /product="hypothetical protein"
                     /protein_id="WP_191701773.1"
                     /transl_table=11
                     /translation="MLDTLTTVSGFLLLATIFYWFHFLDKNKNDERGDHIVGKAAKISF
                     SSLFVIMGIITVFYTTEAITADNLFNYMLIGLSVGTLIHTVSLFLYDRKYQ"
     misc_feature    8672..8685
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.52"
                     /tool="antismash"
     misc_feature    complement(8673..8686)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.86"
                     /tool="antismash"
     misc_feature    complement(8674..8687)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.52"
                     /tool="antismash"
     gene            8800..8994
                     /locus_tag="H9635_RS18390"
                     /old_locus_tag="H9635_18360"
     CDS             8800..8994
                     /GO_process="GO:0050830 - defense response to Gram-positive
                     bacterium [Evidence IEA]"
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790340.1"
                     /locus_tag="H9635_RS18390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_18360"
                     /product="mersacidin family lantibiotic"
                     /protein_id="WP_191701774.1"
                     /transl_table=11
                     /translation="MEKVVGMSMKKLEKGEMEKIYGASGVVEPHTTPILSAATKSSKKC
                     LGAISAISGLVSYNKDCLG"
     CDS_motif       8800..8868
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MEKVVGMSMKKLEKGEMEKIYGA"
                     /locus_tag="H9635_RS18390_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       8869..8994
                     /prepeptide="core"
                     /locus_tag="H9635_RS18390_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="3.30"
                     /molecular_weight="3924.5"
                     /monoisotopic_mass="3922.1"
                     /core_sequence="SGVVEPHTTPILSAATKSSKKCLGAISAISGLVSYNKDCLG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MEKVVGMSMKKLEKGEMEKIYGA"
                     /leader_location="[8799:8868](+)"
                     /alternative_weights="3942.5"
                     /alternative_weights="3960.5"
                     /alternative_weights="3978.6"
                     /alternative_weights="3996.6"
                     /alternative_weights="4014.6"
                     /alternative_weights="4032.6"
                     /alternative_weights="4050.6"
                     /alternative_weights="4068.7"
     gene            9022..9198
                     /locus_tag="H9635_RS18395"
                     /old_locus_tag="H9635_18365"
     CDS             9022..9198
                     /GO_process="GO:0050830 - defense response to Gram-positive
                     bacterium [Evidence IEA]"
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016078397.1"
                     /locus_tag="H9635_RS18395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_18365"
                     /product="mersacidin family lantibiotic"
                     /protein_id="WP_191701775.1"
                     /transl_table=11
                     /translation="MNVNSTVGKSLKKLNKTEMEKVFGATGSEIQPQSTPLCSFLASYI
                     ISAQFKCGGDNKP"
     CDS_motif       9022..9096
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNVNSTVGKSLKKLNKTEMEKVFGA"
                     /locus_tag="H9635_RS18395_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9097..9198
                     /prepeptide="core"
                     /locus_tag="H9635_RS18395_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="2.90"
                     /molecular_weight="3362.8"
                     /monoisotopic_mass="3360.7"
                     /core_sequence="TGSEIQPQSTPLCSFLASYIISAQFKCGGDNKP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNVNSTVGKSLKKLNKTEMEKVFGA"
                     /leader_location="[9021:9096](+)"
                     /alternative_weights="3380.8"
                     /alternative_weights="3398.8"
                     /alternative_weights="3416.8"
                     /alternative_weights="3434.8"
                     /alternative_weights="3452.9"
     gene            9279..10007
                     /locus_tag="H9635_RS18400"
                     /old_locus_tag="H9635_18370"
     CDS             9279..10007
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821814.1"
                     /locus_tag="H9635_RS18400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_18370"
                     /product="flavodoxin family protein"
                     /protein_id="WP_191701776.1"
                     /transl_table=11
                     /translation="MTKKILLYSGSRNLSSRTNIIIEQIHSYIVGNYADIQTTKIDPLS
                     MPLRHSTGCKNCFEHGTCPSEGYADDNGKFLKEKADEADLIIFATPVYSHNVSSDSKIF
                     IDRLSYWGHLMKFAGKSVITIVTCESNGGEHVDSYLKKVFTFMGANILHSEIFFKNYDE
                     DEYREGLEEIESVIHDHYKNDFPVVISDKHESTFQTMKSILNKYPKEHFEYRYWEESGM
                     FKSPTLKEHIKSKSSEGLKC"
     gene            10001..13039
                     /locus_tag="H9635_RS18405"
                     /old_locus_tag="H9635_18375"
     CDS             10001..13039
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="H9635_RS18405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_18375"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_191701777.1"
                     /sec_met_domain="DUF4135 (E-value: 5e-90, bitscore: 294.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.3e-50, bitscore:
                     162.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDNLYLSLNIKERYSILKTNKELLNDLNTKALDSWRSEMSILTD
                     SAFAEMISINNYNLNVFSHVVDKDVSAANKKLYQLYAEKSEWYQKFVQMVNEVNADKSI
                     HFKKDILFLLRPYTYYVEKSIDELLSTPLIKRIVGKEIKKCFVEHFAITAIEIAQKPIV
                     LELNIDREKGELSGESKEDRFKSFIDSFSSNSKLLSFYNKYIVLTRLLTDISLNYIKNA
                     ETLLKRIEENKDLLSSKFGITDFVLEKVKMGQGDTHGRGNTVTELVFKDSTKIIYKPKN
                     VKIHKVYKEFVDIFNKKENILEMQVTEALHLNDYTFEEFIEYKGCNNNNEVKDYYRRFG
                     QLMGILYFLNGTDMHMENLISRGNQPIVVDLETLFQQPIPFDSRDYPIMKDVRKILFGN
                     VTSTMLLPVKHGSGREDDFGVDLSALDGKASKLPRKVLQPVNLGTDEMKYDFKEVSSTD
                     SNNIPFLKDPTDKVYYKDFIDEILIGFKNIALEVMRNKDEFLNGLWLKTLQEDILVRTI
                     FRDTSQYGNILEHSNHPDLLMDMLDRDKVLENMWSFGLSNKKVIYYEIEDMRINDIPIF
                     FSNIKENNLLSSNLYPIEGERDYNSLTLVTDKINNIDNDVLDKQLSVIKVALGLYPKTL
                     PTKTAPLISDVQYEYDFIEEAKKIADFLIENITIEDDKYVYWMSVVHGLDVEWEVGYLD
                     NDFYDGIAGVYLFFESLYLETKIKKYKEYAKKIVNSLKMNFNKNTVGLSSGYVGLIHAT
                     AYIKNRRVIREISEDLQTQFSYLENDHDDIPMDYLNGTPSLINSLLKIYQRDDDMDVLL
                     QATKYAEKYMSLPVAEEMKSDLGFGHGYLSIALVFYRLWNITDNVRYCKSAEQYYSYFE
                     SSYEAEKESLESNLSWCRGLLGVLIGQLEIYQITKDEKHLKIINELEEIIFKMNELNDD
                     GLCHGNIAYSEFFVKKYEYFDSPTDFAHAKNIVQNVLNSAKEGFKLRKTDGFQSLGLFT
                     GLSGIGYQLLRVNNPKKINSILD"
     gene            13059..15191
                     /locus_tag="H9635_RS18410"
                     /old_locus_tag="H9635_18380"
     CDS             13059..15191
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000708395.1"
                     /locus_tag="H9635_RS18410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_18380"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_191701778.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.1e-40, bitscore:
                     130.3, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHKRKVPYIEQMESVECGLACFAMISSYYNLNATLSDIRKENPA
                     PREGFSFLSLSNIANEYGFETNAYKASLEDLKNVRLPCILQWEHNHFVVLEKINKSSYQ
                     ILDPNSGKFSISHEEFKEKYSEYALEIYPGEKGILTGKKGKEERIVSKYLLKHKYIFLS
                     LIGVSILIQGLMALIPLATRWVTDNAINTANIDNLQLFGWLIIVFLFSYVIVQSARAVI
                     IALFQKRLDESIMNDFMNKLYKLPYSFFEHRSKGDLLFRANSAIFIRDIISTSMITIFI
                     DSLLIITYTIVMINFSVQLSMFLFLLSIFLIFFLILNTNIIRQMSKKNLLDKAKTQSVL
                     SENIHNILDIKSLGLEKNRLNLWSEKYGAELKTTQKLNVYQSLIGTVTSLIQVGTPLVI
                     LFLGGGLYIDGKISLGTLFAFSSIAVTFITPIISIGTNYTQLISIGTYFARIKDILTAE
                     EERVGEKEGQKLKGTIEFRNVGFKYNKHSYPVLKDVSFSIERGQKVAIVGPSGSGKSSI
                     AKLLLGLYEASSGKIFIDGKEFSDYSLTDIRYSIGTVLQESKLFSGSIGDNVSMSKNKN
                     KYSDGKLADAAYKAGVLDDILKTPMAFETLISENGNNFSGGQKQRLLIARALYQEPNIL
                     LFDEATSHLDMITEEHISKTLKELNITQVVIAHRLNTIVNADKIIFIEDGEVKEIGTHD
                     ELIEKKSYYYRLYFAE"
     misc_feature    complement(15385..15402)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 22.53"
                     /tool="antismash"
     CDS             complement(15429..15578)
                     /gene="allorf_27695_27844"
                     /locus_tag="allorf_27695_27844"
                     /protein_id="allorf_27695_27844"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MIVMRRNGCLRRVTVLVSSSSDFLDDLPAITGCPFFLHSIFQHQQ
                     GGLF"
     CDS_motif       complement(15525..15578)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MIVMRRNGCLRRVTVLVS"
                     /locus_tag="allorf_27695_27844_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(15429..15524)
                     /prepeptide="core"
                     /locus_tag="allorf_27695_27844_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.70"
                     /molecular_weight="3335.7"
                     /monoisotopic_mass="3333.6"
                     /core_sequence="SSSDFLDDLPAITGCPFFLHSIFQHQQGGLF"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MIVMRRNGCLRRVTVLVS"
                     /leader_location="[15524:15578](-)"
                     /alternative_weights="3353.7"
                     /alternative_weights="3371.7"
                     /alternative_weights="3389.7"
                     /alternative_weights="3407.8"
     misc_feature    15466..15482
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 19.91"
                     /tool="antismash"
     gene            15936..16376
                     /locus_tag="H9635_RS18415"
                     /old_locus_tag="H9635_18385"
     CDS             15936..16376
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025541.5"
                     /locus_tag="H9635_RS18415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_18385"
                     /product="YkyB family protein"
                     /protein_id="WP_191701779.1"
                     /transl_table=11
                     /translation="MKRFENRSVITRMDYPNDNIGRDLKINEIAQAIHVINRRAKVVPD
                     SSALYSLKYAVIKKLLLEQRATKLCVHRFKRVHQLHSIRDSRIDIQTIFVVVSCGEYTF
                     HYPAEKQDIKDLKFEKKIVSIRNPRSEMSYASAKRLLLQYLQ"
     gene            complement(16639..16788)
                     /locus_tag="H9635_RS18420"
                     /old_locus_tag="H9635_18390"
     CDS             complement(16639..16788)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H9635_RS18420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H9635_18390"
                     /product="hypothetical protein"
                     /protein_id="WP_191701780.1"
                     /transl_table=11
                     /translation="MVIQHENNLPLETKEFLKDNGHIIYFEFLIDEQRHYVAVDLETID
                     PEYL"
     misc_feature    complement(17173..17187)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.56"
                     /tool="antismash"
     gene            complement(17208..17939)
                     /locus_tag="H9635_RS18425"
                     /old_locus_tag="H9635_18395"
     CDS             complement(17208..17939)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H9635_RS18425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H9635_18395"
                     /product="hypothetical protein"
                     /protein_id="WP_191701781.1"
                     /transl_table=11
                     /translation="MKSVKIYLAIILGGILLHNLIFIETASATNDSIHTPEETTIISTE
                     IFEPNKSNTNGYFNGEIISPLSNDPGYGAVKINDALSSLNGLREQADRNFTSFESFKGA
                     SIEIASSLPVIGKWVETGSTIWSHLKNVGADIGSGTGKTTDVKTSYSDRYFYHWLYVWD
                     YTNSWKDMGYSVSRYWYKNITVSYLDKSCDCVQNAAYDYSRLANSPNKISKAPNYMNKT
                     RLSTIVQSRWSSNFGSYTESY"
     gene            18275..19144
                     /locus_tag="H9635_RS18430"
                     /old_locus_tag="H9635_18400"
     CDS             18275..19144
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR01716"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /locus_tag="H9635_RS18430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_18400"
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="WP_191701782.1"
                     /sec_met_domain="TIGR01716 (E-value: 1.7e-37, bitscore:
                     120.8, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKGEIFKVLRNSKNITLKQASDGIVSESFLSKFERGKNDISLTN
                     FLLLLEKLNISMNEFNIISEEIDLIFPFKELLNSINSAYQRKDIDLLINIKFELRNQWI
                     KSEIKSYKCNSIMVDALIKNLNPEYKINNTDVEFLKDFLFSRDHWGYYEMTLFGNSLDI
                     FKFELIDLLGNELINQKVFFQDSQHKKEKINILLNITALYIKNNKIKKAEFYSRKANEL
                     LNNENFMLQRCICKFFGGMILFKNGNTVEGENVCRDMIEIMNRLDYKIMSENYKVFFQE
                     NYLVMSAN"
     CDS             19249..19443
                     /gene="allorf_31515_31709"
                     /locus_tag="allorf_31515_31709"
                     /protein_id="allorf_31515_31709"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MKPSSCFLTSSKMLASKAAGGFSFDSYRHPYVQLPPGVINDHKSP
                     LYCLSSPSIKSIALRLIRY"
     CDS_motif       19249..19311
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKPSSCFLTSSKMLASKAAGG"
                     /locus_tag="allorf_31515_31709_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       19312..19443
                     /prepeptide="core"
                     /locus_tag="allorf_31515_31709_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.90"
                     /molecular_weight="4853.6"
                     /monoisotopic_mass="4850.6"
                     /core_sequence="FSFDSYRHPYVQLPPGVINDHKSPLYCLSSPSIKSIALRLIRY
                     "
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKPSSCFLTSSKMLASKAAGG"
                     /leader_location="[19248:19311](+)"
                     /alternative_weights="4871.6"
                     /alternative_weights="4889.6"
                     /alternative_weights="4907.6"
                     /alternative_weights="4925.7"
                     /alternative_weights="4943.7"
                     /alternative_weights="4961.7"
     misc_feature    complement(19610..19623)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 20.74"
                     /tool="antismash"
     misc_feature    complement(19614..19627)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.68"
                     /tool="antismash"
     gene            19798..20691
                     /locus_tag="H9635_RS18435"
                     /old_locus_tag="H9635_18405"
     CDS             19798..20691
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF012798.5"
                     /locus_tag="H9635_RS18435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_18405"
                     /product="site-specific integrase"
                     /protein_id="WP_191701783.1"
                     /transl_table=11
                     /translation="MEETLFSLQQYKMQQQKDETIQAMKKKKLDMYKPDFNLFQAFCEQ
                     NFLAINFDSLELYLHELITHQHARLSTFNRRFAGVKYWLVHEYGLQMTNEQESGVKMLR
                     SLYNEEDYLRLKSMRGIRAEKQTDVLRLIDRYDTGKKGDIRKRAICLVNLITANRPSEM
                     VRLKVSDFDLENRTVQVMMVKQGDMKEKRLTLECVQAVRNYIKACELIAEDYFVGAADK
                     WGNHTSRQISEVSYNQAIQSWLGFAPYTFRKTQITAMYQKGADIPTIAKQSGHKSHQTI
                     MEHYINLRSDDVDEYL"
     gene            complement(21128..22006)
                     /locus_tag="H9635_RS18440"
                     /old_locus_tag="H9635_18410"
     CDS             complement(21128..22006)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037206.5"
                     /locus_tag="H9635_RS18440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_18410"
                     /product="S-4TM family putative pore-forming effector"
                     /protein_id="WP_225231402.1"
                     /transl_table=11
                     /translation="MSEISSILERQNTDENIRYLHAQRQSYKVSKRFYLARMILSIFTP
                     LISIILYFIFNNTLVNYVLIFSSLILILSVILELFEQKYNKIGANIQEIFDTSVFQIRW
                     NSALLDKKISDEELYELASKEETDEEELKNWYSGLESKNEKINILVAQRMNVCWTLQQK
                     KKFKWLLFICLLSLITTFILISSINSFTVNELFLTLIFPATPLFIYLGKNFLEIWQQEK
                     DLERIANYINQLYEKGHPTDNEIRSIQDCIYIFGRLPNHIVPDVFYKKVRKKLENVFRV
                     INRELTSNDKD"
     gene            complement(21999..22988)
                     /locus_tag="H9635_RS18445"
                     /old_locus_tag="H9635_18415"
     CDS             complement(21999..22988)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015010637.1"
                     /locus_tag="H9635_RS18445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_18415"
                     /product="SMODS domain-containing nucleotidyltransferase"
                     /protein_id="WP_225231403.1"
                     /transl_table=11
                     /translation="MTTYTKVNMDNFIKKHINLDTEVTKKARSSRDFLHEQLSALPNKA
                     ENFPRLYPGKEIYNYGSFSRKTKIRPLDDIDFMLIFSADGTTYKHISETIKMTVPESAA
                     NLYKLRDENGYLSSRKIANKIKNNISKVAQYQKSEIRSSQEAVILNLVSYDWTFDIIPA
                     FKTVEESDGRSYYLIPDGDGHWKKTDPRIDQARVTNVNKNTDYNVLEFIRIIKFWNQIQ
                     NIKISSYLLENIVLNYFEEGEGEIWNTKPYQLKSFFNYLSSAIFQPVWDPKSLQGDLND
                     LEHSKQIIIENKANKSMNAASNAITYENDKKYEEADKQWRIIFGDDYV"
     misc_feature    complement(22944..22957)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 25.42"
                     /tool="antismash"
ORIGIN
        1 ttccattaga tgttttataa aaaatcccaa ttccggtagg tagtccaatt gctattttat
       61 cagaaagatt ccatactgga gtttttaacc atcggaaagt tgacatagcc ataaacttcg
      121 tataacctga aacatcacta tcattaaact tatagacatt cccccataag tttagatcag
      181 atttggttaa agcaagtggt tgaatttcag catcattagg ttcttctaca ttataatatt
      241 cgtcaaaatc taagactatt tcagcttgcc cttccactag ggcttttaag tccattaaag
      301 gcatagcttc aatttttttt tcattaaaat tcagattatt atacaaatag tctaattctt
      361 cctctgataa ttgatcaact tgtgcagctt ctgtaaccga attaaaaata aacgctgata
      421 taacaatcgt aatacctatt aaaaatttct tcaactgtat cttcctctct tttataaata
      481 ttgatataac aatgtgcaat aataaattac ttacttccaa ttaaatcaaa tactagtgta
      541 gtaatatcaa gtaataaaat ttccattttt tcacatccct tcaaaaaaat tatacgacaa
      601 aattatccat ttacgttata atgtaaacaa tagttaacat taggcggtgt gaaaatgcaa
      661 attggtgtta tcatcaaaaa actacgaata gataaaaaaa tccaatccaa tactttatat
      721 caaaatctat tatctcgtcc ggccattgcg aaatttgaaa gtggagaaag cgatacgaca
      781 gttgtgaagt ttatgattat cctcgataga ttgaacattt cattagaaga attcgaagtt
      841 gcatatagga tgaatagtac taagaatatt atggaaattt attcgccagg ggcatacaaa
      901 aaggcatttt atgctagaga tgttccggag ctttattatt tgtcgagaat gtcgatgcag
      961 aagtatgaaa aaacaaaact tgtaaaatat caacataata gtgctgtaat caatttacta
     1021 attagcgtta ttgaaaatac atcagacatt atggaagacc gtgaattatt acaaaactat
     1081 ttatcgaaat gcgagtattg gagctattat gaaattacac ttttcaccaa tactttgagc
     1141 ttttattcga atgagtttat tgacgttact tataaacatg ttaaacgagt cttaatctct
     1201 tatcagggat tagtacgata taaaaatgaa ttagcacttt tattgtttaa tattcttcag
     1261 ttaaaaataa caactaatca atttacgtcc cttaattact acttaaatga actcatagtg
     1321 ttaaaggatg aatgtataga taatatgtat gttcaaacaa taatttgttt cttcacatta
     1381 ttaatggaag taatcaaagg aaataaaaat aatatagcag aactctataa aataattgac
     1441 atttttgaat atctagaaat gcaatttaaa gccgatcaat gccgaaagtt gcttactcat
     1501 gtgataaatc attcaagcat taaaacttga tatagcccaa atgagtttat tgcattgaga
     1561 ccaattcgcc acttaattgg caaggttttt aaagaagctg gcgcgtaaaa ccagcgaaat
     1621 aggtgtttcc agttgttttt cttgtgtcct tcagtatcat attaacaaaa aaaggaacaa
     1681 ctttatttgg acaatttttt gtgtttaggg catgacgtga tagtaatgcg ccggaacggt
     1741 tgtctccggc gagttacggt gctggtcagt tcgtcgagtg gttttctcga cgatctgcca
     1801 gcaatcacgg gatgcccttt attttgcaca gtatattctt agtatgaaca tgctcgtatg
     1861 atgaaattta tttcatcatg gcgggctatt tgagatggaa gagcaaacga caaaaaccag
     1921 ctggcaattc agcacgaaca agcggagcga ttcgtgctga attggtcccc cttcctcccc
     1981 taagagcgcc tccaagttta atcctgtcct tgctgacggg ggatggaggg gtttgccggg
     2041 aggtttggag ggcggcaggg gaggaagggg gacggttttc agcgattctc agctgaaaac
     2101 aggctggttt ttgtggtttg cggactttgt tggccgactt gatgataagg gaaatgttta
     2161 ttgagaggga agatttagcg agccatgacg taataatgag gtgccggaac ggttgtctcc
     2221 ggcacttcat ggttttttct tggtgccggt ggttttccgg cacggagaaa aaaattacgg
     2281 gatggcgagc gtgggggaaa tattttttgt ggttatctaa tatttattta atattgttta
     2341 tttaatattt aagaaaatgt gtaaatatca acgtttaatg ggatatgcaa ggtgttcttc
     2401 aatctgtcga aagcattata tgaacttaaa aagaaatatt taatctggta caacacagaa
     2461 tttaaacgca caaatgctgt taaatcaaca tttgtgcgtt taaattaaaa gtccattatg
     2521 taatataaat ttatagcgct tgaccggtat agtataccga gtcaagcgct accaatattt
     2581 tgttcggttt tgtttagcta atgatgaata atgacgttac aatgactaca acttcccaat
     2641 agaaataagg gacagtttga aaggtaataa gtaactttat tagttgcatg tatattttat
     2701 tcaacgtcat cgcctccttt tctttaaaga aaaaggtagc gcttgtttct atttatatta
     2761 tacacggttt cacttaaaag gtttcaccat gtcggtcggt taaatgtact attttgtggg
     2821 ggaatatgaa ttatcggctt cttacgcttc atacaaatga attttcatga tgtgtgggat
     2881 ataaattctt ttatcccctt gaggtgatag ggttgtgata aatgctgcgt tcacgggcag
     2941 tttttttatt gttccttcga ttgtgaagga ttcaccgctg ttccagtaat ggatgaggac
     3001 aacactatgc gtttgtacgg ctgtttgtat ttgatgagcg agttcttcat agtcaaattc
     3061 atcgagttgt ggctcaagta caaaattatc ttcatcgtac cattcacgta ttagttttac
     3121 atgctcgggc atcatcattg ctgtccattt aattgtgcca cgatcccggt ttttattatc
     3181 catttagtca cctctaaaat acggaacgtt tgttcttatc ttagcagaat gatgaaataa
     3241 agtaaaacag gaaaaaatcg ctaaaccctt ttcaccaaag gatttagcga ttttttattt
     3301 ctccttctgc acctttaacg cttcaatttc agcttgatac ttctcacgac tttcatcatt
     3361 aattttacgt aactcagcaa tctctgcata aagcgcctgg atctgttcgt tgtactgctc
     3421 gtttgccttg gctagttggg cttgttgctg acgttccagt tcgactagtg ctttttcacg
     3481 ctctagatct ttgcgttcga tagatagttg gagagtgtct tcaaactttt tctgttctga
     3541 agctaaggtc tttctagatt ctgcaagttc ctgttgaagt gcgttgcctt ttacttctgc
     3601 agcgtttgct tgttctacta atgctgcttt ttcattgctg aaatcgattt tcagctgttc
     3661 attttcttcg gcataggctt ggtattttgc gactaagcca cttaacgtat catttttttc
     3721 tttatattca gcaataaggg cctggttgtt ttccaaggta gtttcattcg cttttaattt
     3781 ctcttttaac tctttttctt gttcttgtaa tgccgttacc atattatttt tcaacgtgat
     3841 ttcttctttt aattggaaaa gttgttgttg gaactcctgg ataatggctt ctttgctctc
     3901 taatttatcg ctaatatctt tcacagcgtg gtccttcaga taaaccgaac gttgaatcat
     3961 attgacgatt agctcataca tgcgggttgt atggtgttca agttccgata aatcttgcgt
     4021 gtagtcactt gaaccttgct taatagtatt caattcatac aatgccacag ccttctcgaa
     4081 ccagtccttt gaagatacac cacttgattc gataaccatc ttcgcttttt catacatttc
     4141 ttcgcttact ttgactccaa atgttttatc agccatttta actcctccta atggttaact
     4201 aataaaatca ataatatcaa agggttaacc tagttttttt aagttaactt tattataatt
     4261 caatgcgact gaaaattcaa atattaatcc tgtattggcg tataaaaaac gctccctgtt
     4321 caagagggaa cgttttgttg atcatcgtat tccaaagatt gtttgtgata ttcgtggagc
     4381 gctaacgtta actgtttaga atagtgttct tcgatataag cagagatata gcgtttctta
     4441 tcaatctcaa tttgcgcaga acggaaaagt ttttggaaaa gcggtttctt ttgttgggta
     4501 tactgttgaa ctgcttcgtt ctgtaaacga ttaagcacgg tttgttcaat agatttttcc
     4561 ctaatacgta ttgcgatatc ctccttatta gatgccatca ttccctcgac cattttcctc
     4621 aactcagtgt tttcctgttc aagatttttt gtgatggttt gaatcttttc taatttttgc
     4681 gaagtttcga gaggaatggc ttttattttt tgttctagaa agtcttgatt tatggttagt
     4741 tgcatttgtt gggtctcttc attttgctcc attttaaata aacctgtctt cataatttgt
     4801 tctaatgctt gactcatggc attgagtttg tattcaatgt catcgggcgt agcaatttct
     4861 gttgaaggag acggtctttt ttggataata tggccatctt catttatccg taaaagttgt
     4921 cttagtcccc ttacgcgata ctcatccttt aatagcagaa tcatacgcaa ttttaaaata
     4981 gctttaaaat ctaaacgaat aagggtagct gttgtgggat ttgtcgcttg gtcatcaaat
     5041 aaatactctt caaagggttt gatgtagtaa cgcagctgtg catccgtaac atcaaaccag
     5101 ctcgccactt cgggtgtgga atagtatttc ttttcaatga gctcgagtaa ataaggctca
     5161 gataaaaaat gctgctcgtt gggtgttcct tggatgactt gaaataaagt atcgtttgca
     5221 aggacttctt ttatacgttg ctcaatggga atcacttgtt ccatattcta ttctctccta
     5281 ttctattcaa aactttttta ttcttttgta cgcaactcta cggaaaactt ttcaattctt
     5341 ttctacgcta gggcaaattt gaaaatattt ctctatttct ctctattctt ttgtgggcgt
     5401 ttttatgcta gttttcttcg gaaagagcgc aaaaaaagcg tcctcatgag attcgagatg
     5461 gataccccat acatcgaatt tatgagaacg ctgagatatt tgatttttca aatagctgac
     5521 agcgagcctt ggagtgatat cccatttcat ttgattaacc tttaaacgtt aatttcaaag
     5581 aggttaacca gttaactatt tataccgtaa ctcaccggag acaacctacg ttgtcgaagt
     5641 aacattcttt aaagtatctt gattgcttct tgactgcttg gcgaaattta tgaagtgcta
     5701 ccataaattg tttgaaaagt gttgttcttt gatgtaagca ccgttacaga agtgcttttt
     5761 ccaaatatct ttaaatagtt taattattaa agcgcaatat atatcaaaaa atattgttta
     5821 aatttgttat aattttgaac taataaaata aatatttaga gatttttaat aaaacttagc
     5881 ttaattataa aggagtagaa acaaatgaat aaaaaggaat caattaaagg gtgggaattt
     5941 ataagttcta ctccagattt atacacattt gagttagacg acaaagtatt ttattcaggt
     6001 agaaaatcag gattgcttaa tgcaaaaata ggagtaagta ctagagaatt tgcaacaata
     6061 gtacagagat ttcaagcaag catttattta gggaaacaaa ttaaaatgtc ttgttattta
     6121 aaagcggagc gagagacaaa atgccaagta tggcttcaaa ttaatgattc atatgatgat
     6181 ataattattt ttaatagtat ggataacagt atttttcaag gaaaaacaga ttggaattat
     6241 tactccataa tacttgatgt acctaaagaa agtgcttgta ttctttttgg aatgcaactt
     6301 tttggtgcgg gaaaagtttg ggttgataat tttaagttcg aagaggtaag tgaaataata
     6361 agtagaacaa ataatgcaga taggaaccta tcagaacaac caattaattt agattttaac
     6421 taatagataa acaataattg aaggctcagg tattcataga atatagtaag agtatgatat
     6481 ttggtaagga atttgaatgg aacaattatg ggtattataa gtttggaata taaacgatta
     6541 aacggcttaa accctcagaa tttaggctca agccgcataa tttctaatgt ctacttgacg
     6601 gggagtaaca attggggtgc aattcactaa aaagaacctt ctatatatta attttcctca
     6661 tgtgtggttt tatgaactgg tctttgtaga caattcactt tcaaatttcc tcttttcacc
     6721 tatattaatg aattttttca ataaaatttc catggggcca ttatcccatt tctttaaata
     6781 taatttgctc aatatagcaa ggaatacata aaccacaaaa gtaattatca caccatttaa
     6841 aactccaatc ttgccaaata aacctaaacc ataaccatag aaaatgaatg taaaaataat
     6901 agaatatgca atgtaatttg ataatgatag tcttcctgta gcaattaaat aggggttaat
     6961 aagtttaaga tatggatata tcgaaaataa aagagaaata taaccaattc ctaaaaaatt
     7021 tgatcctagt gtaaatgtca ttccgtacaa atcgttgtta ggatattgta aatataatag
     7081 tttcattaca atgccaatgg gtattaaaag tattcctata taataatacc ttggatttat
     7141 tttataaaat ttcattttag cagcgtatat acctaacagc gccattggta ataatgtaaa
     7201 aggagaaaca agagtagtta agattagtat aaacgttccc attccttcga tatccagacc
     7261 caaaacttta gttaatgctt ctgattcaag ccgatgttgc agaatttctg aataatgacc
     7321 gtttgagtaa acctcttccg tatttaatat ataggacgat attttatttg gatctagagc
     7381 actctgatta taagatccgt aactaaacaa actaatagtg cctaaaaata taagagccca
     7441 tattaatatt gtatgaggtt ttctcttaat gaacatgaga agaaataatg tagttaaacc
     7501 atacgaaaaa agaatgtcac cctcccatat aaacaaaaaa tgtaaaaatc caattaaaag
     7561 taaaccgatt gagcgtttta aaattatttt agaaggtcga atagtatttg agcttcttct
     7621 gtataaaact aagctatatc ctaataagaa tgtgaaaatt ggtaagaaac taccttctat
     7681 aaggatatag attaaattac gtgtccatat atcagtattt gaatcagtaa aatatattaa
     7741 ttggtctttc cccaaaattc catattgaaa aattaacata ttgactaata aaattcctaa
     7801 aagagagata cctcttaaag catctagctg atcaattctt tttttctgca tttttagctc
     7861 cttaaaaagt atttttgact tcaataaagg caaccaagag attttatttt actgatagaa
     7921 gttcttgatt gccttaaagt aattatttat tcgtcaccaa tgtgtatgaa tacttcttct
     7981 atttgcttac ctaaggcttt tgaaattcta aatgctaaat ccagagaagg attatatcta
     8041 tttttttcaa gagcgactat ggtttgtcga gttactccta cttctttagc tagttgttct
     8101 tgcgtcattt ttttatgagc cctccaaata ctaatttggt tgtctagcat acctatcctc
     8161 ctacctctaa ttcattatta tttcgaaata taattattcc ttactggtat ttccgatcat
     8221 acagaaagag gctcactgta tgaattaagg ttcctactga tagtccaatt aacatgtagt
     8281 taaaaaggtt atccgcggtg atagcttcag tagtgtaaaa aacggtaatt atccccatta
     8341 tcacaaataa tgaagagaat gaaattttgg ctgctttccc tactatatgg tcacctcttt
     8401 catcattttt atttttgtct aagaagtgaa accagtaaaa aatggttgct aatagtagga
     8461 atcctgagac agttgtcaac gtatcaagca tttcaatacc tccaattttt tattataaat
     8521 ttaaagtaac atatttctta cattttgtaa agcatttctt acgtcaatag acaccattcg
     8581 ataatattgt gaatatttat aatcgtttgt aaagtaatgt atttaagtca atttgtaatg
     8641 aattctagat aaaaagaata aaatatttta cattttttta aaaaaatcct tgatttagat
     8701 attttgggat gttaagttat ttgtaacaaa taaaggaaaa aaatatgaca tatttttaca
     8761 taatttttcc aatatttgaa attttatagg aggtgcgtta tggaaaaagt agttggaatg
     8821 agcatgaaaa agttagagaa gggtgaaatg gagaaaattt atggggcttc tggtgtagta
     8881 gaaccacata caactccaat ccttagtgct gctactaaaa gtagtaagaa atgtttagga
     8941 gcaatctctg caatcagtgg tctagtttct tacaacaaag attgtttggg atgattttac
     9001 aaaaaggagc gtgactatta aatgaatgtt aactctactg ttggtaaaag tttgaaaaag
     9061 ttaaataaaa cagagatgga gaaggttttc ggagctacag gctctgaaat tcaacctcaa
     9121 tctacaccgc tttgtagctt cctagcttca tatattatat ctgctcagtt taaatgtggc
     9181 ggagataata aaccttgatt tgtatagttt cttaaagtat tttgggcaaa gtgttgaatt
     9241 tcactttgcc tatttttata aaggaaggga gtataaaatt gactaaaaaa attttactat
     9301 actcaggatc aagaaacctg agttctagaa caaatattat tattgaacaa atacattcat
     9361 atatagttgg aaattatgct gacatccaaa cgacgaaaat agatccatta tcaatgccac
     9421 ttagacattc gaccggttgt aaaaattgtt ttgagcatgg gacttgtcct tctgagggat
     9481 atgctgatga taacgggaaa ttcttaaagg aaaaagcaga tgaagctgat ttaatcatat
     9541 tcgctactcc tgtatattca cataatgttt catctgacag caaaattttt atagatagat
     9601 tatcttactg gggccactta atgaagtttg ctggaaaatc ggttataacg attgttacat
     9661 gcgaaagtaa tggaggggaa catgtagata gttatcttaa aaaggtgttt acatttatgg
     9721 gtgcaaatat attacactct gaaattttct ttaaaaatta tgatgaagat gaatataggg
     9781 aaggtctaga agaaatagaa tctgttatac atgatcatta taaaaatgat ttcccagttg
     9841 taattagtga taaacacgag agtacgttcc aaactatgaa atcaatttta aataaatatc
     9901 caaaagagca ttttgaatat cgatattggg aagaaagtgg gatgtttaaa agccctactc
     9961 taaaagaaca tataaaatct aaatcaagcg aggggttaaa atgttagata acctatattt
    10021 aagtttaaac atcaaggaaa ggtattctat tttaaaaaca aacaaagaat tattaaatga
    10081 tttaaatacc aaggcattag atagctggcg atcagaaatg agtattttaa cagatagtgc
    10141 atttgccgaa atgatttcca tcaacaatta taatcttaat gttttctcac atgtagttga
    10201 taaagatgta tctgcagcta acaaaaagtt atatcaatta tatgcagaga aatcggaatg
    10261 gtatcaaaaa tttgtacaaa tggtaaatga agtgaatgca gataagagta ttcacttcaa
    10321 aaaagatatt ttatttttac taagacctta tacatactat gttgaaaaat caattgatga
    10381 attactttct actccattaa ttaaaaggat agtaggtaaa gaaataaaaa aatgctttgt
    10441 agagcacttt gcgattactg ctatagaaat tgctcaaaaa cctattgttt tagagttaaa
    10501 tatcgatagg gaaaaagggg aattatccgg tgaatctaag gaagacaggt ttaaatcttt
    10561 catagattca ttttcttcta attccaaatt actttccttt tacaacaaat acattgtgtt
    10621 gacacgcctg cttacagata tttctttgaa ctatattaaa aatgcagaaa ctttgctgaa
    10681 aagaatagag gaaaacaaag acttattgtc atccaaattt gggatcactg attttgtatt
    10741 agagaaggtc aaaatgggac aaggagatac tcatggacgt ggtaatacag taacggagtt
    10801 agtttttaaa gatagcacaa agattattta caaacccaaa aatgtaaaga ttcataaagt
    10861 atataaagaa ttcgttgata ttttcaataa aaaagaaaat atattagaga tgcaagtaac
    10921 agaagctctt catcttaatg attatacgtt tgaagaattt atagaatata aggggtgtaa
    10981 taataataat gaggtaaaag attattaccg acgctttggg caattaatgg gtattctata
    11041 tttcttaaat ggaacagaca tgcatatgga aaatttaata tcacgtggta atcaaccgat
    11101 cgtagtcgat ttagaaacgt tattccaaca accaatccca tttgattcaa gggactatcc
    11161 tattatgaaa gatgtacgaa aaattttgtt tggtaatgta acttcaacta tgctactacc
    11221 tgtcaaacat ggatctggga gagaagatga ctttggcgtg gatttaagtg ctcttgatgg
    11281 aaaagcttct aaattaccaa ggaaggtttt acagcctgta aatttaggaa ctgatgaaat
    11341 gaaatatgat tttaaagaag tatccagtac tgactcgaat aatattccat ttttaaaaga
    11401 tccaacagat aaagtgtatt ataaagattt tatagatgaa atcttaattg gatttaaaaa
    11461 tattgcttta gaggttatga gaaacaaaga tgagttcctg aatggattat ggttaaaaac
    11521 gcttcaagaa gatattttag ttagaaccat cttccgagac acaagccagt atggaaatat
    11581 attggaacac tctaaccatc cagatttatt aatggatatg ctagatcgcg ataaagtact
    11641 ggaaaatatg tggagctttg gcttatctaa taaaaaagtt atttattatg aaatagaaga
    11701 catgagaatt aatgatattc ctattttttt ctcgaatata aaagaaaata atttactcag
    11761 cagtaatttg tatcctattg aaggtgagag agactacaat agccttacat tggtaacaga
    11821 taaaataaat aatatagata atgatgtttt agataaacag ctctctgtaa taaaagtagc
    11881 tttaggtctt tatccgaaga cattacctac taaaacagca cccttaattt cagatgttca
    11941 atatgaatac gattttatag aggaagcgaa aaaaattgct gattttttaa tagaaaatat
    12001 tactattgaa gatgacaaat atgtgtattg gatgtctgta gtacatggtt tggatgttga
    12061 atgggaagtt ggctatttag ataatgattt ttatgatggg atagcaggag tttatttatt
    12121 tttcgagtca ctttacttag aaacaaaaat taaaaagtat aaagagtatg ctaagaaaat
    12181 agtcaactct ttaaaaatga atttcaataa aaacactgta ggattaagta gcggatatgt
    12241 tggactaata catgctactg cttatatcaa aaataggaga gtaatacgag aaataagcga
    12301 ggatcttcaa acacaattct cttatcttga aaatgatcac gatgatatcc cgatggatta
    12361 cttaaatgga accccaagtc taatcaattc cttgttaaaa atataccaac gagacgatga
    12421 tatggatgtg ctattacaag caactaaata cgccgaaaag tatatgtcct taccagtggc
    12481 agaagaaatg aaatctgact taggctttgg gcatggttat ttaagtatag cgctagtgtt
    12541 ttatagattg tggaacataa ctgataatgt tagatattgc aaaagtgccg agcaatatta
    12601 tagttatttt gaaagcagtt atgaagctga aaaagaaagt ttggaatcaa atttatcctg
    12661 gtgtcgtggt ttgttaggcg tattaatcgg acagttggaa atatatcaaa taacaaaaga
    12721 cgagaagcat ctaaaaatca ttaatgaact tgaagagatt attttcaaaa tgaatgaact
    12781 taatgatgat ggattgtgcc atggtaatat cgcatactct gagtttttcg ttaaaaagta
    12841 tgaatatttt gattccccta cagattttgc tcatgcaaaa aatattgtcc aaaatgtatt
    12901 aaattcagcc aaagaaggat ttaagttaag gaaaacggat ggatttcaat cattgggatt
    12961 atttactgga ttatcaggaa ttggctatca actattgagg gtcaataatc cgaaaaaaat
    13021 aaactccatt ttagattaaa aaaaggaata caaacaatat gaagcacaag agaaaagtac
    13081 cttatattga acaaatggaa agtgtagaat gcggactggc ttgctttgcg atgatttcaa
    13141 gttactataa tttaaatgca acactaagcg atattagaaa agaaaatcct gctccaaggg
    13201 aagggttttc ttttctaagt ttatccaata tagctaatga gtatggattt gaaactaatg
    13261 catataaagc tagtttagaa gacttgaaga atgtacggct accctgtatt cttcagtggg
    13321 aacataacca ctttgtagtt ttagagaaaa taaacaagtc aagttatcaa atattagatc
    13381 ctaatagtgg taaatttagt atatcccacg aagaattcaa agaaaaatat agtgaatatg
    13441 ctttagaaat ttatcctgga gaaaaaggga ttcttactgg aaaaaagggg aaagaagaaa
    13501 gaatagtaag taaatattta ttaaagcata aatatatttt tctaagttta attggtgtat
    13561 caatcttaat tcaagggtta atggccttaa ttccattagc tactagatgg gtaacagata
    13621 atgctattaa cactgcaaat atagataact tacaattgtt tggttggtta ataattgttt
    13681 tcttattctc gtacgtcata gtccaatctg ctagagcagt aatcatagct ttgttccaaa
    13741 agcgtcttga tgaatctata atgaatgact ttatgaataa gttatataag ctaccttatt
    13801 cgttctttga gcatcgaagt aaaggtgatt tgttatttag agctaattca gcaatattta
    13861 ttagggacat aatatctaca tcaatgatta cgatatttat agatagttta ttgattatta
    13921 catacactat agtaatgatt aacttttcag tacaattgag tatgtttttg ttcctattaa
    13981 gtatttttct aattttcttc ttaattctaa atacgaatat tattaggcag atgtcaaaaa
    14041 agaatttgtt ggataaagct aaaactcaat cggttttatc tgaaaacatc cataatatct
    14101 tagatattaa aagtctagga cttgaaaaga acagactaaa tttatggtca gaaaagtatg
    14161 gtgctgaatt aaaaacgaca caaaagttaa atgtatatca atctttaata ggtacagtca
    14221 ctagtctaat acaagttggt acccctttag ttattctgtt tttaggggga ggcttatata
    14281 tagatggaaa aatatctttg ggtactctct ttgcatttag ttcaattgca gttacattta
    14341 taaccccaat tatttcaatc ggtacaaatt atacgcagct aatttcaatc gggacatatt
    14401 ttgcgagaat aaaagatatt cttacagcag aggaagaaag agttggcgaa aaagaaggac
    14461 aaaaattaaa aggtactata gaatttagaa atgttggatt taaatataac aaacatagtt
    14521 atcccgtatt gaaagatgtt agtttttcta tagagagagg acaaaaagta gctatcgttg
    14581 gaccttcggg atcagggaaa agttctatag cgaaactact gttagggcta tatgaagcat
    14641 catcaggtaa aatttttatt gatggaaaag agttttcaga ttatagcctc acagatatac
    14701 gatattcaat tggtacagta ttgcaggaat ctaagttgtt ttcaggttct attggagaca
    14761 atgtttcaat gtcgaaaaat aaaaataaat atagtgacgg gaaattagca gatgctgcat
    14821 acaaagcagg tgtattagac gatattctga aaactcctat ggcttttgaa accttaatat
    14881 cagaaaatgg taataatttt tcaggtggtc aaaaacaaag gcttttaatt gctagagcct
    14941 tatatcaaga accaaacatt ttactttttg atgaagcaac aagccatcta gatatgataa
    15001 ccgaagagca tattagcaag acacttaaag aattgaatat tacacaagtc gttatagctc
    15061 accgtctaaa tactattgta aatgcagata aaattatttt tattgaagat ggggaagtta
    15121 aggaaatagg cacacatgat gaattaatag agaaaaaatc ttattactat agattgtact
    15181 ttgcagaata agtatttttt acaaggtatt tatttcaata tcttctagag ctatgaatag
    15241 ctcttttttt gttatgtagc tatcagtaaa atataggggt cgttaacttt tattatagcg
    15301 aaggaaataa ttaaaggaaa tcgaaaaaag cgctcagatg aattgagatg catgatgaac
    15361 caataaactt cttcacaaaa tcattatggg ctttatggaa tattactcat taccgcttgt
    15421 ttgccctcct aaaatagccc gccttgttgg tgctgaaata tactgtgcaa aaagaagggg
    15481 catcccgtga ttgctggcag atcgtcgaga aaatcactcg acgaactgac cagcaccgta
    15541 actcgccgga gacaaccgtt ccggcgcatt actatcacgt catgccctcg ctccgtataa
    15601 atttagactt cagatagagt gcattaataa agtgcctgct cctaacacgc gattggacaa
    15661 aaaacatcag gcatgttgaa aaaccttcac ggcatcgagg taaacctcgc taccgctcgc
    15721 gtttttaaca tgcctgtgca gctctaagct tgcattgtgg tggaaacctg caccaccaca
    15781 atgcaaacta agagctgatt ttttgtcaaa tcacttaaaa taaactaatt cagcaaaaaa
    15841 aaacgttgaa acagtgactt tccggagaat atgaagttta cggttttacc aaccgtaaaa
    15901 atactgtaaa atatctccaa agaggtgatg attaaatgaa acgctttgaa aatagaagtg
    15961 ttattactcg aatggattac ccaaatgata atataggtag agatttaaaa ataaatgaaa
    16021 ttgcacaggc cattcatgta attaaccgca gagccaaggt tgtaccagat tccagtgccc
    16081 tctattcgct gaaatatgca gtaatcaaga agctactatt agaacagcgt gccacaaaat
    16141 tatgtgtcca tcgatttaaa agagtccatc aacttcattc aattcgagat tcaagaattg
    16201 atatccaaac aatattcgta gtagtttctt gtggtgaata taccttccat tatcccgctg
    16261 aaaaacaaga tattaaggat ctgaaatttg agaaaaaaat cgtcagtatt cgaaatccac
    16321 gttctgaaat gagttatgcc tcagctaagc gactactctt acaatatctc cagtagggat
    16381 accgtaactt gccggctaac cgtagcacag agatggactc ccctatagtt tttcttgcag
    16441 gtctctattg cttcttaaaa ccatcccgcg tttatacatc ttaaattgaa tcactgtatt
    16501 ttgtattttg aaaagaagtt ccttttcgca cattgaaaag acgttggttc aatatggaac
    16561 caacgtcttt ttgttgtttt tgtagtattc tacgaaatag ttgataactt attaaacgtc
    16621 atttgagtgt atttataatt acaaatattc aggatctata gtttcgagat cgactgcaac
    16681 atagtgtcgc tgttcatcaa ttaagaattc aaaataaata atatgaccgt tgtcttttaa
    16741 aaattccttt gtctctaatg gcaaattatt ttcatgttgt ataaccatag attgagtcgc
    16801 ttctattgtt tgctgaggct tcaatttctg acttctaaag tctatatact ctctgcttaa
    16861 ataatatgaa ttcaactctt taggaaaata gccgatgtag gcaatattta tatgctgctc
    16921 agttaaattt ttaacttgaa actgaaaggt taaccttttt tcaaattcat tttccgtgtc
    16981 gtcgatacga aaagtttttt gcttaatcga aataatttcc tgtaatactt tattctcagc
    17041 agggttagtt aggttatcta ttcctagtgc aacttgctca taagagtttt gttcagatgt
    17101 agaatcagtt tgttgtgtac agccacttag acatatacta agtagaatta ttaatataat
    17161 tttagatatt ggaattttca gataaataac cccctttttt cgaattctca gtaggattca
    17221 gtatatgaac caaaattact gctccaacgg ctttggacaa tagtacttaa tcgtgtttta
    17281 ttcatatagt taggagcttt tgaaatttta tttggactat ttgctaatct tgaatagtca
    17341 taagctgcat tttgaacgca atcacaagat ttatctagat aactaactgt tatattttta
    17401 taccaatatc gacttacact ataccccata tctttccaag aatttgtata atcccatacg
    17461 tatagccaat gatagaaata gcggtcagag taactagttt taacgtctgt agttttacca
    17521 gtcccactcc caatatcagc acctacattt tttagatgtg accaaatagt tgaaccggtc
    17581 tcaacccatt ttccaataac agggagtgaa gaggcgattt caatactagc ccctttaaaa
    17641 gattcaaacg aagtaaaatt tctgtcagct tgttctctga gaccgttaag agatgataat
    17701 gcatcattaa ttttcactgc gccatatcct gggtcattac ttaatggact aatgatttca
    17761 ccattaaagt agccattcgt gttactctta tttggttcaa aaatttcagt actaataatt
    17821 gtcgtttcct caggagtatg gatgctatca ttagttgcac ttgctgtttc aataaaaatt
    17881 agattatgca acaaaatccc ccctagtatt atagctagat atatttttac acttttcata
    17941 ttatacctcc aattaaaaaa attttataat tctacactta ggattttaaa taatagagaa
    18001 tgagtagtat aatttcgaaa attatcaata agtattataa ttattatggt acttcaagta
    18061 ttttttttgt ttcattttaa aatacttgat ttagatttga aatattttca ccgcctccac
    18121 ctataatgag ataaatacct aagccaataa ctattaaata ataaagcaaa gcatttctat
    18181 tcattttctc cccccttact tccatattta actaaattat aataagatat ttaccataag
    18241 tatttttttt gtcatatatg aaagtaggtt agatatgaat aaaggtgaaa tctttaaagt
    18301 cttaagaaat tccaaaaata taactttaaa acaggcctca gatgggattg tgagtgagtc
    18361 atttttatca aaatttgaga gaggtaaaaa tgatatatca ctaactaatt ttttattatt
    18421 attagaaaaa cttaatataa gtatgaatga atttaatatt atttctgaag aaatagattt
    18481 aatatttccg tttaaggaat tattaaattc aattaattct gcatatcaaa gaaaagatat
    18541 agaccttctg ataaatatta aatttgaact acggaatcaa tggataaaat cagagataaa
    18601 atcttataaa tgtaatagta taatggtaga tgcgcttata aaaaatctaa atcctgaata
    18661 taaaataaat aatacagatg ttgaattttt aaaagatttt ttattttcta gagaccactg
    18721 gggttattat gaaatgacgt tatttggtaa ttcattagat atatttaaat ttgaattaat
    18781 tgatttatta ggaaatgagt taataaatca aaaagtattc ttccaagata gtcaacacaa
    18841 aaaggaaaaa ataaatatac ttttgaatat tactgcttta tacattaaaa ataataaaat
    18901 aaaaaaggct gaattttata gtagaaaagc taatgaacta ttaaataatg aaaattttat
    18961 gttgcaaaga tgtatatgta aattttttgg aggtatgatt ttatttaaaa acggaaatac
    19021 agttgaggga gaaaacgttt gcagagatat gattgaaatt atgaacagac tagattataa
    19081 aataatgagt gaaaattata aagttttttt tcaagaaaat tatttagtca tgtctgctaa
    19141 ttaactaatt atttttgtta gaattttaat taggtagatg tatgaaacat tatttctaaa
    19201 aatattagct tcataatacc ttacctttgg ataaatatta ataaattctt gaaaccgtca
    19261 agctgttttt taactagttc taagatgcta gcttcgaaag cagcgggtgg tttttcattc
    19321 gatagctatc gccatccata cgtccaactt ccaccaggtg taataaacga tcataaatca
    19381 cctttgtact gccttagttc cccatcaatt aaatccattg ctctacgtct tattcgatat
    19441 tagaatagtc gctctatcat tccaattcgc aatatctctg tagattctgc tatctgcaaa
    19501 aattcctata attgaatggt ttcctgcata ttatacgttc ctatgtaata cttactaaaa
    19561 ttattaacct taaaaaataa tgcttgttta aggttgagaa tggtataata aaagaaacgt
    19621 ttgttctcct gaaaagtcag attccttcaa taaaatattt aggtaaaggc aaaggtctta
    19681 cttaccaaaa gtaatttctc tttcatggaa cacatacata ttggctgatg aatcaaaaga
    19741 ataaaaaaga atagaaaaga aataaaaaga acggaatgga atagggaggt atatataatg
    19801 gaagaaactc tgttttcttt gcagcaatat aagatgcagc aacagaaaga tgaaacgatt
    19861 caggcgatga aaaagaagaa gctcgacatg tacaaaccag atttcaattt atttcaggcg
    19921 ttctgtgagc agaacttttt agcaatcaat tttgactcgc ttgaacttta tttacacgaa
    19981 ctcattacgc accaacatgc acgcctttca acatttaacc gcagatttgc cggggtgaaa
    20041 tactggctgg tccatgaata cggactgcag atgacgaatg agcaagagtc gggtgtgaaa
    20101 atgctgcggt cactctacaa tgaggaagat tatctgcgct taaaatcgat gcgtggtatt
    20161 cgtgccgaga aacaaacgga tgtgctacgt ttaatcgatc gctatgatac ggggaagaaa
    20221 ggcgatatcc gtaagcgtgc gatttgtctc gtaaatttaa tcactgccaa ccgaccgtcg
    20281 gaaatggtgc gcctcaaagt aagtgatttt gatttagaga atcgaacggt tcaggtgatg
    20341 atggttaaac aaggcgacat gaaagaaaaa cgcctgacac tcgagtgcgt gcaggcggtt
    20401 agaaattata taaaagcatg tgaactgatt gccgaagatt attttgtcgg tgctgcagat
    20461 aaatggggca accatacaag ccgtcaaatt agtgaagtaa gctataatca agccattcaa
    20521 agctggcttg gctttgctcc gtatactttc cgtaaaacac agattacggc aatgtatcag
    20581 aagggagccg atattccaac gattgcaaaa cagtctggtc ataaatcgca tcagacgatt
    20641 atggaacatt atattaattt gcgatcagat gatgttgacg agtatttata aatgcacaat
    20701 ataatagtag aaactcatat ttttatgaac tacttcatcc aactctaggt taattcatta
    20761 aaaaatacgt aaaaagtggc gctcagtcaa attgagatgg aatagataat tcatcatctc
    20821 aattcaattc atctgagcag gtattgtcag gtatttaaag agggaaaata atttaataac
    20881 aggataaatt tcttggactc acccctttaa acaaattgct tcaatgggta attccaattt
    20941 gtacccgtga tctttaaact ggattaaatc catgttagga taattgttaa atgcctgtga
    21001 aggtttgttt cttaatgatg aaattgtgcg ctttacgaac atggaggtag ttgaataaat
    21061 gcaataagaa gcgtgctcaa atgttaaatt gggcacgctc ttgaatttat tatcaattac
    21121 aattacttta atctttatcg ttagatgtaa gttctctatt tataactcga aatacatttt
    21181 ctaatttctt tctaactttt ttataaaata catctggaac aatatgatta ggcagcctgc
    21241 caaatatata aatgcaatct tgtatagagc gaatttcgtt gtctgtagga tgtccctttt
    21301 catataactg gttaatataa ttcgcaattc tctccaaatc tttttcttgt tgccagattt
    21361 caaggaaatt ttttcctaaa taaataaata agggtgtagc agggaatatt aaagtaagaa
    21421 ataattcatt aactgtgaaa ctattgatac ttgatatgag aataaatgta gtaattaaag
    21481 ataataaaca aatgaataaa agccatttga attttttctt ttgttgtagg gtccaacaga
    21541 cattcattct ttgtgcaact aagatattta ttttttcatt tttagactct agtccggagt
    21601 accaattttt tagttcttct tcatctgttt cttctttaga ggcaagctca tataattctt
    21661 catcgctaat ttttttatct aatagggcac tattccatct gatttgaaag acactggtat
    21721 caaaaatttc ttgaatatta gcgcctattt tattatactt ttgctcaaat aattctagta
    21781 ttaccgataa gattagtata agtgagctga atattaaaac ataattaact aaagtattat
    21841 tgaaaataaa atacaggata attgatatta atggtgtgaa gatacttaaa atcattcgag
    21901 ctaaataaaa tcttttagat actttataac tctgtctttg ggcgtggaga tatctgatgt
    21961 tctcatcggt attttggcgc tcaagtattg atgaaatttc agacatagtc atcaccgaaa
    22021 ataatacgcc attgtttgtc agcttcttcg tatttcttat cattctcata agtaatggca
    22081 ttacttgcag cgttcatact tttattagct ttattttcaa taataatctg cttagaatgt
    22141 tctaaatcat ttaaatcacc ctgcaatgat tttggatccc acactggctg gaaaatggca
    22201 gatgataaat aattaaagaa tgatttaagt tggtatggtt tagtattcca aatttcccct
    22261 tctccttctt caaagtaatt taaaacaata ttttctagta ggtaagagga aattttgata
    22321 ttttgtattt gattccaaaa tttaatgatc cggataaatt cgagtacatt gtaatcagta
    22381 tttttattta catttgtaac cctagcctga tctattctag gatctgtttt tttccaatga
    22441 ccatctccat ctggaatcaa gtaataagat cgcccatctg actcttctac cgttttaaat
    22501 gcggggataa tgtcaaatgt ccaatcatag cttactaaat ttaaaataac ggcttcttga
    22561 cttgaacgga tttctgactt ttggtactga gccacttttg aaatattatt tttaatttta
    22621 ttagctatct ttctagagct taaatatccg ttttcgtctc gtaatttata caaattagca
    22681 gctgattcag gtacagtcat tttaatagtt tctgaaatgt gtttataagt cgtaccgtct
    22741 gcagaaaaaa tcaacataaa atcaatatca tctaaaggtc taattttagt tttacgagaa
    22801 aacgaaccat aattatatat ttctttacca ggatagagac gagggaaatt ttctgctttg
    22861 ttaggtaatg cggataactg ttcatgtaaa aaatctcggc tcgaacgggc ttttttcgtt
    22921 acttctgtat ctaaattaat gtgttttttt ataaaattgt ccatatttac ttttgtataa
    22981 gtggtcatta aaaggctcct ttgtttcata aattgataaa ggcaaaagtt actgctcac
//
