LOCUS       NZ_JACSPZ010000002     24257 bp    DNA     linear   CON 20-NOV-2024
DEFINITION  Solibacillus faecavium strain A46
            NODE_2_length_683913_cov_34.541886, whole genome shotgun sequence.
ACCESSION   NZ_JACSPZ010000002
VERSION     NZ_JACSPZ010000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Solibacillus faecavium
  ORGANISM  Solibacillus faecavium
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Caryophanaceae;
            Solibacillus.
REFERENCE   1  (bases 1 to 683913)
  AUTHORS   Gilroy,R., Ravi,A., Getino,M., Pursley,I., Horton,D.L.,
            Alikhan,N.-F., Baker,D., Gharbi,K., Hall,N., Watson,M.,
            Adriaenssens,E.M., Foster-Nyarko,E., Jarju,S., Secka,A., Antonio,M.,
            Oren,A., Chaudhuri,R., La Ragione,R.M., Hildebrand,F. and
            Pallen,M.J.
  TITLE     A Genomic Blueprint of the Chicken Gut Microbiome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 683913)
  AUTHORS   Gilroy,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-AUG-2020) Microbes in the Food Chain, Quadram
            Institute BioScience, Norwich Research Park, Norwich NR4 7UQ, United
            Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.1
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 160x
            Sequencing Technology             :: Illumina NextSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014836905.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 02:01:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,850
            CDSs (total)                      :: 3,809
            Genes (coding)                    :: 3,795
            CDSs (with protein)               :: 3,795
            Genes (RNA)                       :: 41
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 14
            CDSs (without protein)            :: 14
            Pseudo Genes (ambiguous residues) :: 0 of 14
            Pseudo Genes (frameshifted)       :: 3 of 14
            Pseudo Genes (incomplete)         :: 10 of 14
            Pseudo Genes (internal stop)      :: 2 of 14
            Pseudo Genes (multiple problems)  :: 1 of 14
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:04:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 511811
            Orig. end                         :: 536068
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JACSPZ010000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24257
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..24257
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24257
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:14257](-)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14257)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     misc_feature    complement(96..109)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     18.25"
                     /tool="antismash"
     gene            complement(354..1043)
                     /locus_tag="H9635_RS06025"
                     /old_locus_tag="H9635_06020"
     CDS             complement(354..1043)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010291077.1"
                     /locus_tag="H9635_RS06025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_06020"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_191699245.1"
                     /transl_table=11
                     /translation="MTVELLNITKTYKKNRGVHNIEVTIDAGEITALVGANGAGKSTII
                     KLLTGQLMQDEGEIIGFSKEALRYMPDDLNFPDTLTAAEILALLANLKKVPSDKIPKLL
                     EQVGLADKGHLRVSEYSKGMRQRLNLAQSLIGDGDLYILDEPTNGLDPFWIATLKKMLV
                     DEKEKGTHVLFSTHLLSFAEEIADQVIMLHEGEVIAKGNIQTLLTTYHCQTLEQLWLTL
                     TSLENVQ"
     gene            complement(1051..1848)
                     /locus_tag="H9635_RS06030"
                     /old_locus_tag="H9635_06025"
     CDS             complement(1051..1848)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010291076.1"
                     /locus_tag="H9635_RS06030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_06025"
                     /product="ABC transporter permease"
                     /protein_id="WP_191699246.1"
                     /transl_table=11
                     /translation="MIKFIQLEMKQLIRSKWLQIVTILFVVTFTSVLMIQQIAMPDAEG
                     FTRQSAAMLNVLLFLLPLFILTIGSMSLAADRESGWLNLLKTYPMSNGKYIFTKWIGLF
                     NVFLFITLLAITLSYMMGSFFGGISLNGPFIVFILILLLLFTSLSIFVGVIAKNRLHAL
                     ALALGVWSIITLILSYVLMAVGTIISENLLKTFISLSIHINPLEWLRFSYFVFTDQSAV
                     LGPAFYELVKFYDSTVGLFYYSLFTALWGVSPLLLATYLLKRR"
     gene            complement(1845..2306)
                     /locus_tag="H9635_RS06035"
                     /old_locus_tag="H9635_06030"
     CDS             complement(1845..2306)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004230382.1"
                     /locus_tag="H9635_RS06035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_06030"
                     /product="nitrous oxide reductase accessory protein NosL"
                     /protein_id="WP_191699247.1"
                     /transl_table=11
                     /translation="MKRLLVISTIIAMMLLAGCGNKEYKPKEISAETDVCEICNMTISH
                     MDYAGQIVFKNNDHLVFDDLGCLMEYIIANGESEIGAAYIKDESTNKWINVKEAVYIYE
                     ANYWTPMNYGVLAFASQESVEAYMNENGQGKQLKYDDLITFEWGIHTHE"
     gene            complement(2303..3577)
                     /locus_tag="H9635_RS06040"
                     /old_locus_tag="H9635_06035"
     CDS             complement(2303..3577)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016906.5"
                     /locus_tag="H9635_RS06040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_06035"
                     /product="nitrous oxide reductase family maturation protein
                     NosD"
                     /protein_id="WP_191699248.1"
                     /transl_table=11
                     /translation="MKKLMKWAVFTLLFTFLPYVSHSVAAESLQQLIDETSPNSTLYLK
                     NKTYEGPVTITKPITIIGDKETKIMSLSTGITIADTNNITLQAIQFETEQAPVLVEDSE
                     EIEFKNLNLIIDENGMEFYRVKNVTLSDLKIEGRKEGHFSKKPNGISLFEGEQITVKKL
                     SVQNVQDGMYFEKTKNVDVQHTIVEDGRYGLHFMYGTNIQLQHNTVKNNVSGMTIMVVE
                     NAYIAHNQIERQLQLNSNGMYLYDIEEAQITNNIFKENTTATIWNQVKNTAFSKNMFQS
                     NGTVIHSRRSPTVTVTENEFQGNILTARSDEIGFVLNRNHYDDYNGYDFNADGLGDTDY
                     HSFTSFGQWMVRKPVYQYYVESPSVTLLNKLDQQLSDTQNMVLVDKNPLMTTEKKEQSI
                     QLNWLHLLGSTASLFVLFSIWRKLR"
     gene            complement(3647..4285)
                     /locus_tag="H9635_RS06045"
                     /old_locus_tag="H9635_06040"
     CDS             complement(3647..4285)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004224489.1"
                     /locus_tag="H9635_RS06045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_06040"
                     /product="nitrous oxide reductase accessory protein NosL"
                     /protein_id="WP_318245181.1"
                     /transl_table=11
                     /translation="MFKKILLAGIITMLLSACNQTEEKNEPTVSNEESAQQQEVEQIAE
                     KDWTQDARLQEPTEDTVCAMCNMKVYTKDHEMGVFSAQAIKEDGSIAFYDDIGCLLNAE
                     FANVEVNEKFVRDYKTLNWFNVEQAYIVKTKLKSPMNWGYIFFKYEDDAKTYMDENEGS
                     ELTSYTKVRQQALERRKAKMKAGENIDKHDPEDGHVHHEGEELKHNDGE"
     misc_feature    4533..4547
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.7"
                     /tool="antismash"
     misc_feature    4546..4559
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 20.34"
                     /tool="antismash"
     gene            complement(4580..5626)
                     /locus_tag="H9635_RS06050"
                     /old_locus_tag="H9635_06045"
     CDS             complement(4580..5626)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1241: lipoprotein
                     dsbF"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014823855.1"
                     /locus_tag="H9635_RS06050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_06045"
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="WP_191699250.1"
                     /transl_table=11
                     /translation="MTYLTLGQVNIPIAWLALIIAILYSDFRSRHSDGATTKLIEHLLY
                     TYIFIWKFSYILFSSSDFFQAPLSLIYFDGGLKGHLLALAVVAFLLYRKRELFDWEVGW
                     MYWVRLVAIYQLIFNSFQEQWFVAGLWIFTLILIERIKSQHVLLVQFFLLMWLDGFISS
                     FTLFHVAVLLTVYFRTKHAQYIAGAGLLSLVAMMLMDVEENITTTTRAAIDLPATTGEQ
                     YRLSDQEQSLTVVNFFATWCPPCKAEMPHLQSFADSLPMGVALIGINLTARDNGEEALT
                     DFMETYSVTYPILRDEDDAVGKAFQVKSIPTTVLLNAQGEELERIVGPVSEEGLRQLIK
                     KYESLLSE"
     misc_feature    complement(5643..5657)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 20.05"
                     /tool="antismash"
     gene            complement(5663..7354)
                     /locus_tag="H9635_RS06055"
                     /old_locus_tag="H9635_06050"
     CDS             complement(5663..7354)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008407215.1"
                     /locus_tag="H9635_RS06055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_06050"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_191699251.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 5.2e-64, bitscore:
                     211.7, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVVIIGGVAGGASAAARIRRLDEQAEIVMFEKGPHVSFSNCSL
                     PFYLSGVVADSKKLLMMTPDSFEAKHNIDARINSEVIAINRADKMVTVKNTVTGERTTE
                     SYDQLVLSPGASPIVPKLPGNDLPHVFTVRNVVDIERLHNAIVENDAQNIAVIGGGFIG
                     VEVAENLRLAGRNVSLVEFAPQILTPFDDDMAQILHKEMVDQGVELIVGDGLAEITPNL
                     IKLNSGKEVAADIVVLAIGVRPETTLATEAGLEIGEKGAIKVNQNYQTSDPNIYAVGDA
                     IEVYHRLMNKQTRLALAGPAQRQARAVADHMYGIPVLNKGVIGSSSIQVFDYAAASTGL
                     NERTAKEMGLLVEAVYIIAPDKVGLMPSSNPLHFKLVYELPTGRIVGAQAIGKGNADKR
                     IDVIATLITMNGTIEDLKELELSYSPMFSTAKDVVNLAALVATNLMAGRFKQVRVNDVR
                     RLVEEDAFIVDVREANEFAQGALKGAVNIPLSELRERMEEIPTDVPVYVHCRSSQRSYN
                     AVMALNNSGYTNVANISGSFLGISLYEYYQDQVNNREPIVTAYNFK"
     gene            complement(7682..9220)
                     /locus_tag="H9635_RS06060"
                     /old_locus_tag="H9635_06055"
     CDS             complement(7682..9220)
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008176114.1"
                     /locus_tag="H9635_RS06060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_06055"
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_191699252.1"
                     /transl_table=11
                     /translation="MTKLTVENKHQEMKNNVLKGGHEKYHEKNQEQGKLFVRERLELLF
                     DEGLQAEDGTFANVLAGDLPADGVVTGIGKIHGRTVCVMANDSTVKAGSWGKLTVEKII
                     RIQETAEKLNVPLLYLVDSSGARITDQLEMFPGRRGAGRIFYNQVKLSGRIPQICLLFG
                     PSAAGGAYIPAFCDVVVMVEGNASMYLGSPRMAEMVIGEKVDLETMGGAKMHCSVSGCG
                     DVLAKTEEEAIAYARQYISYFPDNFKNKPNVEEPKLPKTFEKSIEEIIPANQNAPFNMY
                     DLIDRIIDEGSFCEVKKLFAPEIITGFGRINGQSVGIIANQPRVKGGVLFHDSADKAAK
                     FINLCDAFHIPLIFLADVPGFMIGTNVEKMGIIRHGAKMIYAMSEATVPKITVIVRKAY
                     GAGLYAMAGPAFEPDVCIALTGAQIAVMGPEAAINAVYANKIAALPKEEQAAFIDQKRE
                     EYQEEIDVYRLASELIIDDVIEPNELRKTLEIRLEAYKTKNLTFTERKHGVSPV"
     gene            complement(9237..10016)
                     /locus_tag="H9635_RS06065"
                     /old_locus_tag="H9635_06060"
     CDS             complement(9237..10016)
                     /EC_number="4.2.1.17"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (6-251). E-value: 7.3e-74. Score:
                     240.1. Matches aSDomain:
                     nrpspksdomains_H9635_RS06065_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012292663.1"
                     /locus_tag="H9635_RS06065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_06060"
                     /product="enoyl-CoA hydratase"
                     /protein_id="WP_191699253.1"
                     /transl_table=11
                     /translation="MPNFVKVEVQDGVAVVTFMRAEAANALSVQMLHEINEALEAIHDD
                     RSIRVVIVTGDGEKAFCAGADLKERKGMNEGETRKTIALIGKTMNHFEALAQPVIAAIN
                     GVAFGGGLELALACDIRIASNTAKMGLTETALGIIPGAGGTQRLPRLIGIGKAKELIYT
                     ARRLTAEEAYQYGMIEHITQPEKLLEQAKELAYEIAKNAPLSLIQAKTAINQGMQTDIS
                     TGLQIESLAYSRLLQTEDRIEGLKAFQEKRPPAYRGK"
     aSDomain        complement(9264..9998)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_H9635_RS06065_ECH.1"
                     /evalue="7.30E-74"
                     /label="H9635_RS06065_ECH.1"
                     /locus_tag="H9635_RS06065"
                     /protein_end="251"
                     /protein_start="6"
                     /score="240.1"
                     /tool="antismash"
                     /translation="VEVQDGVAVVTFMRAEAANALSVQMLHEINEALEAIHDDRSIRVV
                     IVTGDGEKAFCAGADLKERKGMNEGETRKTIALIGKTMNHFEALAQPVIAAINGVAFGG
                     GLELALACDIRIASNTAKMGLTETALGIIPGAGGTQRLPRLIGIGKAKELIYTARRLTA
                     EEAYQYGMIEHITQPEKLLEQAKELAYEIAKNAPLSLIQAKTAINQGMQTDISTGLQIE
                     SLAYSRLLQTEDRIEGLKAFQEK"
     gene            complement(10001..10921)
                     /locus_tag="H9635_RS06070"
                     /old_locus_tag="H9635_06065"
     CDS             complement(10001..10921)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016992215.1"
                     /locus_tag="H9635_RS06070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_06065"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_191699254.1"
                     /sec_met_domain="HMGL-like (E-value: 1.5e-50, bitscore:
                     167.6, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLPKQVQIKEVGPRDGLQNETTFIPTEEKIQLVNRLSESGLNYI
                     EVTSFVHPKWIPQLADAVEVLKEIKRNSAITYAALVPNSKGLARALDVGVDEVSIFMSA
                     SEGHNKSNINKSIDETFPILKEVVDGALAAGKTVRGYISTVIACPYDGYTKPEQVVNVA
                     EKLFDMGISELSLGDTTGVGVPTQVDALLHEMLRHFKGEKLAMHFHDTRGTAIANVMTS
                     LAHGITKFDSAIGGLGGCPYAKGASGNVATEDLLYFLHEMGIETGVSLEKIQQTALYVE
                     GIIGKTLSSKLVAIAREEGESCQIS"
     gene            complement(10935..11147)
                     /locus_tag="H9635_RS06075"
                     /old_locus_tag="H9635_06070"
     CDS             complement(10935..11147)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016992214.1"
                     /locus_tag="H9635_RS06075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_06070"
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="WP_191699255.1"
                     /transl_table=11
                     /translation="MTIVKASMAGTVWKILVKEGEQVTAGQDVAILESMKMEIPIVTEE
                     AGTVKRIIVAEGDFIDEANDLVEIG"
     gene            complement(11240..12601)
                     /locus_tag="H9635_RS06080"
                     /old_locus_tag="H9635_06075"
     CDS             complement(11240..12601)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003352521.1"
                     /locus_tag="H9635_RS06080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_06075"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_191699256.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 3.6e-07, bitscore:
                     25.8, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 1.5e-10, bitscore:
                     36.3, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="RimK (E-value: 1e-08, bitscore: 30.4,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 1.9e-15,
                     bitscore: 52.3, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKKVLIANRGEIARRIIRTCNRLGIETVAIYSEADANSLHVKEA
                     TESFCIGKPPVTQSYLNIDSILDVAKQTGSDAIHPGYGLLSENATFAKRVEEAGLTFIG
                     PKFEVIQSMGSKIEARKTMEQAGVPIVQGVNEPIADTDEAAKIAEDIGYPVMLKASAGG
                     GGIGMQLVNNEQELRKAFEGNQKRAQSFFGDGTMFIEKFIAEPHHIEVQVLADAFGSVI
                     PVYERECSIQRRNQKVVEEAPSPFISEETRKKMLDAAVNAAKHIGYTNAGTIEFLVDCD
                     QNFYFLEMNTRLQVEHPVTEEITGLDLVEQQLKIANGEKLAFTREDIQQKGHAIEVRIY
                     AEHPVTFFPSPGKITKLVLPEGEGIRHEVAVETGSEVTPFYDPMIGKLVVFGSTREEAC
                     VRLADALRSYVVEGIQTNIPMLLETVTHEQFLAGSTTTKFVEEYYLPKTKAVGK"
     gene            complement(12614..14257)
                     /locus_tag="H9635_RS06085"
                     /old_locus_tag="H9635_06080"
     CDS             complement(12614..14257)
                     /NRPS_PKS="Domain: AMP-binding (12-445). E-value: 8e-101.
                     Score: 329.5. Matches aSDomain:
                     nrpspksdomains_H9635_RS06085_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012292658.1"
                     /locus_tag="H9635_RS06085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_06080"
                     /product="AMP-binding protein"
                     /protein_id="WP_191699257.1"
                     /sec_met_domain="AMP-binding (E-value: 2.3e-106, bitscore:
                     351.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAELVYQTIGELLEEKAAQYPNREALVYSDRDYRMTYAQFNKHSD
                     LVAKALMAIELEKGHHFSVWTTNVPQWPGLQFGSGKMGAPLVTVNTSYRTSELEYLLKQ
                     SDSRAIILIDNYRDHAFIDTLYDLCPELKECEPGKLQSTRLPLLKSVVVISDKKYPGTF
                     TYEEFLANGSRISDEQLEQRKQSLNYDDVINIQYTSGTTGFPKGVMLRHSNLINNAINI
                     AECMKLTHEDRLCIPVPFFHCFGCVIGTLAIVSVGGTMVPVQEFHPEEVLRTVEKEQCT
                     ALHGVPTMFISELNLPNISSFDVSSLRTGVMAGSNCPIEVMRDVINKLGMEDVTICYGQ
                     TESSPVLTQTRVDDPLNLKVETVGRALPNVEVKIMKPGTNEEVPRGEQGEICARGYVVM
                     KGYYNNPDATKEAIDTDNWLHTGDLGTMDENGYVRVTGRLKDMIIRGGENVYPREIEEF
                     LYQHPKVLDVQVTGVPDEKYGEEVAAWIILKEGQTAVEEEIRDFCKGKISRHKIPRYIF
                     FVDSYPMTASGKIQKFKIREQFASLVKTMH"
     aSDomain        complement(12923..14221)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_H9635_RS06085_AMP-binding.1"
                     /evalue="8.00E-101"
                     /label="H9635_RS06085_AMP-binding.1"
                     /locus_tag="H9635_RS06085"
                     /protein_end="445"
                     /protein_start="12"
                     /score="329.5"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="LEEKAAQYPNREALVYSDRDYRMTYAQFNKHSDLVAKALMAIELE
                     KGHHFSVWTTNVPQWPGLQFGSGKMGAPLVTVNTSYRTSELEYLLKQSDSRAIILIDNY
                     RDHAFIDTLYDLCPELKECEPGKLQSTRLPLLKSVVVISDKKYPGTFTYEEFLANGSRI
                     SDEQLEQRKQSLNYDDVINIQYTSGTTGFPKGVMLRHSNLINNAINIAECMKLTHEDRL
                     CIPVPFFHCFGCVIGTLAIVSVGGTMVPVQEFHPEEVLRTVEKEQCTALHGVPTMFISE
                     LNLPNISSFDVSSLRTGVMAGSNCPIEVMRDVINKLGMEDVTICYGQTESSPVLTQTRV
                     DDPLNLKVETVGRALPNVEVKIMKPGTNEEVPRGEQGEICARGYVVMKGYYNNPDATKE
                     AIDTDNWLHTGDLGTMDENGYVRVTGRLKDMIIR"
     CDS_motif       complement(13022..13108)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_H9635_RS06085_0003"
                     /evalue="5.60E-07"
                     /label="NRPS-A_a6"
                     /locus_tag="H9635_RS06085"
                     /protein_end="412"
                     /protein_start="383"
                     /score="22.0"
                     /tool="antismash"
                     /translation="PRGEQGEICARGYVVMKGYYNNPDATKEA"
     CDS_motif       complement(13622..13675)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_H9635_RS06085_0002"
                     /evalue="3.80E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="H9635_RS06085"
                     /protein_end="212"
                     /protein_start="194"
                     /score="22.5"
                     /tool="antismash"
                     /translation="IQYTSGTTGFPKGVMLRH"
     CDS_motif       complement(13988..14032)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_H9635_RS06085_0001"
                     /evalue="3.20E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="H9635_RS06085"
                     /protein_end="90"
                     /protein_start="75"
                     /score="-1.4"
                     /tool="antismash"
                     /translation="QFGSGKMGAPLVTVN"
     gene            complement(14284..15426)
                     /locus_tag="H9635_RS06090"
                     /old_locus_tag="H9635_06085"
     CDS             complement(14284..15426)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015864021.1"
                     /locus_tag="H9635_RS06090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_06085"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_191699258.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 5.2e-39, bitscore:
                     128.9, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.2e-27, bitscore:
                     91.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 8.4e-52, bitscore:
                     170.8, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFELSKEQEMIRDMVREFAQAEIAPHARELDEKHQFRKESFDKM
                     GELGLFGIPFPEEYGGSGGDTISFALAVEEIGRACGGTGLSYAAAVSLGATPFYNFGTE
                     EQKLEYLVPMAQGKTFGSFGLTEPNAGSDAGGTRTNAYLEGNEWVINGEKCWITNASYA
                     RQIVVTAVTGKDERGKNIITAIIVPTDTPGVTIRSEYQKMGVRASNTCEIVLENVRVPK
                     ENVLGDEKKGFGQFLNTLDGGRISIAALSVGIAQSAFEKALQYSKERVQFGKSISKLQA
                     IQFKLADMAMEIELARNMVMKAAWLKDEGKPFKKEAAFAKLFASEMGFRTCNQAIQIHG
                     GYGYMAEYDVERHLRDIKLMEIGEGTSEIQRVVISRVLGC"
     misc_feature    complement(15477..15490)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.15"
                     /tool="antismash"
     gene            complement(15524..16141)
                     /locus_tag="H9635_RS06095"
                     /old_locus_tag="H9635_06090"
     CDS             complement(15524..16141)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017437437.1"
                     /locus_tag="H9635_RS06095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_06090"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_191699259.1"
                     /transl_table=11
                     /translation="MVVKSLKERIIETALDLFRHKGYHGVSVDEIVETAGTSKGGFYHK
                     FKSKDALLYEIHDLFISHVLKETKKAYEENDTPIDKVTALLFAFTNVFDVYQRHITVFY
                     NESAYLPLEYKNIIKEKRKEYQKLIEQVIEEGKEGGQFRPEISTTITTMAIIGLVNWTY
                     KWYRQNGSLTMEQITHHFNDLILRGVLTEQGLEEAKAKKYIM"
     gene            complement(16306..16956)
                     /locus_tag="H9635_RS06100"
                     /old_locus_tag="H9635_06095"
     CDS             complement(16306..16956)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010332435.1"
                     /locus_tag="H9635_RS06100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_06095"
                     /product="CoA transferase subunit B"
                     /protein_id="WP_191699260.1"
                     /transl_table=11
                     /translation="MSVKERIVKRAVKEIRNGMNVNLGIGMPTLVANEIPSDYQVLLQS
                     ENGLLGIGPYPDESEVDPDLINAGKETVTAVPGASFFDSAESFAMIRGGHIDVAILGGM
                     EVSEKGDLANWMIPGKMVKGMGGAMDLVQGAKRVIVIMEHVSKYGESKIKKECTLPLTG
                     KKVVHRLITELAVFDFTEKGMVLIELASGVSVEEIREKTEADFLVSENLIKYT"
     gene            complement(16953..17660)
                     /locus_tag="H9635_RS06105"
                     /old_locus_tag="H9635_06100"
     CDS             complement(16953..17660)
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004229828.1"
                     /locus_tag="H9635_RS06105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_06100"
                     /product="CoA transferase subunit A"
                     /protein_id="WP_191699261.1"
                     /transl_table=11
                     /translation="MHKVEKNIHGIVGEVQDGATILVGGFGLCGIPELAIEAIRQKGIK
                     DLTVVSNNCGVDDWGLGLLLANKQIKKMIASYVGENKTFEQQFLSGELEVELTPQGTLA
                     ERIRAGGAGIPAFYTATGVGTLIAEGKPVKEFDGKEYIEERAIVGDYAFVKAWKADKLG
                     NLVYRKTARNFNPIMATAGKITIAEVEEIVEVGELNPDEIHTPAVFVQHVILGEGYEKK
                     IEKRTIKVEEAIG"
     gene            complement(17924..19096)
                     /locus_tag="H9635_RS06110"
                     /old_locus_tag="H9635_06105"
     CDS             complement(17924..19096)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008408933.1"
                     /locus_tag="H9635_RS06110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_06105"
                     /product="MFS transporter"
                     /protein_id="WP_191699262.1"
                     /transl_table=11
                     /translation="MQRIFQYFHPLVWIILSGTIFVRTASFMAIPFLALYLHNELQASP
                     LLIGVTIGIAPLFSTFGGLIGGYLTDRFGRKAVIIITVFIWSLTFVGFALAPSAVYFVL
                     LNAVNGLCRSFFEPGTQALMIDFTEDAKKRRLFSVRYTAINIAAVMGPLLGVWVASLAS
                     PATPFMITGFMYALYGLFLIIVLNRYEMKQKRLSSKHQIRTILSAVFHDQKLLLFIAGG
                     ILITVGYSQFNSTLPQFINMNVEDGVKLFSYVIVANSITVLAFQLPLTVVSERISIYSS
                     LKIGVVIFAVGLFLFGVSDSSWMFIASMIVFSVGEIFCFPMMNAVIEEIAPEDQKGTYL
                     GASQFKNIGGFIGPILGGWLLTASINYMFAIISLIMLCSIFIYNRAQRLT"
     gene            19252..20499
                     /locus_tag="H9635_RS06115"
                     /old_locus_tag="H9635_06110"
     CDS             19252..20499
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014824186.1"
                     /locus_tag="H9635_RS06115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_06110"
                     /product="MFS transporter"
                     /protein_id="WP_191699263.1"
                     /transl_table=11
                     /translation="MKLTKEEKSWILYDCGNSAYSIAITTALFPIVFGMFNGVNNMDLG
                     YFNSLASIFVAVLSPILGAFADYKDKKKRFFTFFALVGIISTLSFTFISPESGQWQLLI
                     VMYILSCIGFAGANIFYDSFLVDVTTDEKMDKVSSSGFAFGYISSVIPFGISLAVIFVM
                     GMDEAIGYQIGFCITALWWGLLTIPMIRDVKQRHYIEPEPNPVGNSFKRLGQTFLNIKD
                     YKIVFLFLIAYFCYIDGVDTIIKMVVPYATSVLGPDSLNTFMLLGILLVIQIVAFPFAL
                     LYGSLAKKYSTRSMIIAGITTYMVVCIAAFFISEMWHIFVLGIMIGSAQGGIQALSRSY
                     YGKIIPKERSNEFFGFYNIFGKFAAIIGPFLMALTTTLTGEARYSILSIIPLFIIGLIV
                     FLMLPKDVGQQTRTVR"
     gene            20504..21787
                     /locus_tag="H9635_RS06120"
                     /old_locus_tag="H9635_06115"
     CDS             20504..21787
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014824187.1"
                     /locus_tag="H9635_RS06120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_06115"
                     /product="alkaline phosphatase family protein"
                     /protein_id="WP_191699264.1"
                     /transl_table=11
                     /translation="MTQKSKYVIVVSYDAFSIDNWESAKSKSNLAKLIENGASTNLVKS
                     VYPTLTYVIHSSYVTGMYPDKHGVFHNNPFQPFVPESEQNWHWFRKDIQAPTVYEAAHK
                     KGLTTAGLLWPVTGKAQINYNIPEIKAVKNENQALKILKSGSKLFTLQMELKYGKIRQG
                     INQPNLDDFTTVCAVDTIKKKKPNLLLMHLIDLDDSKHLHGTQGAHIEQVIDRMDRRIG
                     DLVQATKDAGIYDETTFIIVGDHSQLDVQYKVYLNRLFYEEGLIYEQHGAWHWRAYVQG
                     AGGAAYLHVQPGDSDAERIALSILQDAKQHESYGIEAILSTQELNELHVNNQFRFMIEA
                     KEGYSFGDDHLQEAIIDLHAQGKKYATHGYLPSKANYTSNLIISGNQVIAGTDIGEVSV
                     VDIGPTIAHILNLDLPNTDGRALTEIFK"
     gene            21865..22620
                     /locus_tag="H9635_RS06125"
                     /old_locus_tag="H9635_06120"
     CDS             21865..22620
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.5"
                     /locus_tag="H9635_RS06125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9635_06120"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_191699265.1"
                     /transl_table=11
                     /translation="MLINEFSDNLSKYKLPEEYDETYKNYTADLDFIKAHLGENKSAII
                     ELACGTGRLAIPLAKKGHMVYGVDIDQGMLDFARKKALSEDVDIHLSVQDCTQLNLPIT
                     SNFIYMTGNSFQHFLTNESQDALFISVKKHLNPGGEFLFDTRNPILHELAKDEIYEESI
                     EKNGETFTVVNQEKYDPLTQVLHCTSTYKSTQNEYVDSINLRYTYPIEMKRLLEQHGFE
                     LIHLYGSWTKASFNANSISMVIHAKLKEV"
     gene            complement(23323..23784)
                     /locus_tag="H9635_RS06130"
                     /old_locus_tag="H9635_06125"
     CDS             complement(23323..23784)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H9635_RS06130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H9635_06125"
                     /product="hypothetical protein"
                     /protein_id="WP_191699266.1"
                     /transl_table=11
                     /translation="MNREEIKHYVNELHWHLPEETQQDAINWLVANMPLNQLASVFPTY
                     GKSYWQNSVKVVMEIGYPYNIAAFPNMVELFQDLNWPGAEDAVQYFQTLEKQIVTPFLE
                     AGGKQAMIEQDEQWLWFLYAVCERLQMDRADFRDGTVFDAMEETYARDA"
ORIGIN
        1 attaacaaac ttttgcacat cgtcctgcct gtctttcgtt gtcatgttca ctgccaatat
       61 ttcaagctgg tcattatatt cctcatacaa acgttgcaaa tgaggtgcct ccattttaca
      121 aggttcacac cacgaagccc aaaagttcac aatcgtccat ttcccttgag aatccgacag
      181 tgagtattgt tgctcatcca gtgcttgcaa tgtgaaatta gctgctttta gaacacgtac
      241 accttcttca ttagtagtta tagttgatgg tatcttttca ttgcttgccc tgctactttc
      301 ccatattaaa attccgatta gtattgtgat tattacaagt ccaatatatt tcttcactgg
      361 acattctcca gagatgttaa agttaaccac agttgttcta acgtttgaca atggtaagta
      421 gttagaagcg tttgaatatt ccctttcgca attacttcac cttcatgaag cataatcact
      481 tggtccgcaa tttcttcagc aaaggaaagt aaatgggtag aaaacaatac atgagtccct
      541 ttttcctttt catctacaag catttttttc aatgtcgcaa tccaaaaggg gtctaagcca
      601 ttcgtcggtt catctaatat atataaatcc ccatcgccta ttaaactttg agctaaattt
      661 aaacgttggc gcatcccttt ggaatactcc gaaacccgta aatgaccttt atcagctaat
      721 cctacctgtt ccagaagttt tgggatttta tcggagggca cttttttcaa attggctaat
      781 aaggctaata tttcagcagc cgttaatgta tccggaaaat ttaaatcatc cggcatatat
      841 cggagtgcct cttttgaaaa accaatgatt tccccttcat cttgcatgag ttgcccggtt
      901 aacaatttta taatagtact tttccctgcg ccatttgctc cgacaagtgc cgtaatttca
      961 ccagcatcaa ttgtcacctc aatattgtgc acgccccggt ttttcttata tgttttcgta
     1021 atgttcaaca attccacggt catatattta tcaccttctt tttaataaat atgtagctaa
     1081 taaaagtggg ctaactcccc atagtgctgt aaataagctg taataaaata gtccgactgt
     1141 tgaatcataa aatttcacca actcatagaa agccggtcct aaaacagctg actgatccgt
     1201 aaatacaaaa taactaaagc gcaaccattc aagtggattt atatggatgg ataacgaaat
     1261 gaaagttttc aataaatttt ccgaaataat ggttcctacc gccattaaca catacgataa
     1321 aatcagtgta attattgacc aaacacctaa agcaagtgct agtgcgtgta gcctgttttt
     1381 tgctatcaca cctacgaaaa tactaagtga tgtgaaaagt aacagcaaaa taagaataaa
     1441 tacgatgaac ggaccattta gtgaaatgcc gccaaaaaag ctccccatca tataggaaag
     1501 tgtaatggct aatagtgtaa tgaataagaa tacattaaat aagccgatcc acttcgtaaa
     1561 aatatactta ccattggaca tcggataggt tttcagtaaa tttaaccatc ctgattcacg
     1621 gtccgccgct agactcattg aaccaattgt caatataaat aacggaagta aaaataataa
     1681 tacgtttaac attgctgctg attgacgcgt aaatccttct gcatcaggca ttgcaatttg
     1741 ttgaatcatt aacacggatg taaaggtaac aacaaataat atggtaacga tttgaagcca
     1801 tttactacgg attaattgct tcatctcaag ttgaataaac tttatcattc gtgcgtatgg
     1861 attccccatt caaaagttat taaatcatca tatttaagct gtttaccttg tccattttca
     1921 ttcatataag cctccacact ttcttgtgat gcaaatgcaa gtacgccgta gttcataggt
     1981 gtccagtagt tcgcttcgta gatgtacacg gcctctttaa cattaatcca tttatttgtt
     2041 gattcatctt taatatatgc cgccccaatc tcgctctcgc cattagcgat aatgtattcc
     2101 atcaaacagc ctaaatcatc aaaaacgaga tgatcattat ttttaaacac aatttgacct
     2161 gcgtaatcca tatgtgaaat tgtcatatta caaatttcac atacatctgt ttctgcagaa
     2221 atttctttcg gcttgtattc tttattgcca cagcctgcta ataacatcat tgcaataata
     2281 gtacttataa ctaatagccg tttcatctta atttcctcca aatactaaat aatacgaata
     2341 aacttgccgt acttcccaat agatgtagcc agttcagttg aatgctttgt tcttttttct
     2401 ccgtcgtcat aagcggattt ttatcaacta agaccatatt ttgtgtatcg gagagttgct
     2461 gatccaattt attaagtaat gtgacactag gggattctac ataatactga tacacgggct
     2521 tacgcaccat ccattgtcca aaacttgtga atgaatggta gtctgtatcg cctaatccat
     2581 cagcattgaa atcatagccg ttataatcgt cataatggtt acgatttaac acaaagccaa
     2641 tttcgtctga ccgagccgtt aatatattac cttgaaactc attttcagta actgttacgg
     2701 ttggtgacct tctactgtga atgaccgttc catttgactg aaacatattc ttgctaaatg
     2761 ctgtattctt tacttgattc caaatcgtcg cagtcgtatt ttccttaaat atattattcg
     2821 tgatttgcgc ttcttcaata tcatataaat acatgccgtt actgtttaat tgaagctgtc
     2881 tctcgatttg gttatgggca atataagcat tttcaacgac cataatcgtc atgcccgata
     2941 cattattctt aaccgtattg tgttgcagct gtatattagt accatacatg aaatgcaatc
     3001 cataccgccc atcttcaact atcgtatgtt ggacgtctac attttttgtt ttctcaaaat
     3061 acataccatc ttgaacattt tgaaccgaaa gtttttttac tgtaatttgt tccccttcaa
     3121 ataggctaat cccgttaggc ttttttgaaa aatgcccttc ttttcttcct tctattttta
     3181 agtcggaaag agtaacattt tttacgcgat aaaactccat accgttttca tcaataataa
     3241 ggttcaaatt tttaaattca atctcttcac tgtcttcaac aagtacaggt gcttgttccg
     3301 tttcaaattg aattgcttga agagtaatat tatttgtatc cgctattgta attcctgtgg
     3361 ataaggacat aatttttgtt tctttgtcgc caatgattgt aataggtttt gtaatggtga
     3421 ctggcccttc gtacgttttg ttttttaaat aaagcgtact attgggacta gtttcgtcta
     3481 ttaactgctg taagctttca gctgctacgc tatgtgaaac gtagggaagg aaagtaaata
     3541 gcagcgtaaa aacagcccat ttcattaatt ttttcataag caaaatgcac ctctattaac
     3601 ggtgtgtata cagagattag tcgctttcag acgaatcacc tgctgattat tctccatcat
     3661 tgtgctttag ttcttcccct tcatgatgga catgaccatc ttcaggatca tgcttgtcaa
     3721 tattttctcc cgctttcatt tttgctttac ggcgttctaa agcttgttga cgtacttttg
     3781 tataggatgt caattccgat ccttcatttt catccatata cgttttggca tcatcttcat
     3841 atttaaagaa aatataaccc cagttcatcg gtgattttaa ctttgttttg acaatataag
     3901 cttgctctac gttaaaccaa tttaatgttt tataatcacg tacaaatttt tcatttactt
     3961 ctacgttggc aaactcagca ttcagtaaac aaccgatatc atcataaaat gcaatggacc
     4021 cgtcctcttt aattgcctga gccgagaata cacccatttc atgatctttt gtataaactt
     4081 tcatattaca catggcgcat actgtatctt ctgtaggctc ttgcaaacgt gcatcctgcg
     4141 tccaatcctt ctcggcaatt tgttcaactt cctgctgctg tgcagattct tcgtttgaaa
     4201 ctgttggctc attcttctct tcagtttggt tgcaagctga taataacatt gtgattattc
     4261 ctgccaataa tattttttta aacacgtaca tcactccatt tcttatattt cgcttactat
     4321 gataacactt ggttagaata ttatatttga caaagtaatc acaatatttt gtgctaattg
     4381 tgaaattttt ataataccca tgtaggtata aaaaatccca taaataaaag ccgctaaatt
     4441 tcgcggcttt aaatgactat tttttgtttg ttatatcaat atatttatct acctttaatt
     4501 ctcgagatct ttgacactat atgataccca tttgaaaatt tttttcaaac ggtagattga
     4561 ggtggagcat aaacatcaat tattcactca ataatgattc atattttttg attaattggc
     4621 gcaatccttc ttcacttacc ggacctacaa tccgttcaag ctcttccccc tgtgcattaa
     4681 gcaataccgt cgtaggaatg gattttactt ggaaagcttt tcctactgca tcatcctcat
     4741 cccttaagat tggatacgtc acgctgtatg tttccataaa atctgtaagt gcttcttccc
     4801 cgttgtcacg tgccgttaaa ttaataccga ttaaagcaac ccccataggt aagctatcag
     4861 caaaactttg caaatggggc atctccgctt tacatggcgg gcaccacgtt gcaaaaaaat
     4921 taacaaccgt taaagattgt tcctggtcag acaggcgata ttgttcacct gtcgtagctg
     4981 gtaaatcaat cgctgcacgg gtcgttgtcg ttatgttttc ttcaacatcc attagcatca
     5041 ttgcaactaa gcttaaaagt cctgcacctg ctatatattg agcatgcttc gttctaaaat
     5101 aaactgttag taatacggcg acatgaaaaa gcgtaaagct agaaataaag ccgtctaacc
     5161 acatgagcag gaaaaattga acgagcaaaa catgctgact ttttattcgt tcaattaaaa
     5221 taagggtaaa aatccacaaa cctgcaacaa accactgttc ctgaaaactg ttaaaaataa
     5281 gctgataaat ggcgacaagt cttacccaat acatccagcc aacttcccaa tcaaacaatt
     5341 cccgttttct atacaatagg aaagcaacaa ctgccagtgc taacagatgg ccttttaaac
     5401 caccatcaaa ataaattagt gataatggtg cttgaaagaa atctgagctt gaaaaaagaa
     5461 tataactgaa cttccaaatg aaaatataag tataaagcaa atgttcaatt agtttagttg
     5521 ttgctccatc cgaatggcga ctacgaaaat cgctataaag gatggcaatg atcaatgcga
     5581 gccatgcaat cggaatattt acttgtccca atgttaaata tgtcatgttt cattcctttc
     5641 caatcgcaga gctcccaaaa cgttacttaa agttataagc tgtgacaatt ggttcacgat
     5701 tgttcacttg atcttgatag tattcatata aggaaatacc taaaaatgaa cccgagatat
     5761 tcgctacatt tgtatagcca ctattattaa gtgccattac tgcattatag ctacgctgtg
     5821 atgaacggca atgtacataa acaggaacat ctgtcggaat ttcttccata cgctcacgta
     5881 attcgctcag tggaatattt acagcccctt ttaacgcccc ttgcgcaaac tcatttgctt
     5941 cacgcacatc gacaataaaa gcatcttctt ctactaaacg gcgtacatcg ttcacacgca
     6001 cttgcttgaa gcgacccgcc attaaatttg ttgccactaa agccgctaaa ttcacaacat
     6061 cttttgctgt actaaacata ggcgaatacg aaagctccaa ctcttttaag tcctcaattg
     6121 tcccgttcat tgtaatcaat gtcgcaataa catcaattcg cttatctgca ttaccttttc
     6181 cgattgcttg cgcaccgaca atacgacccg taggcaactc ataaactaac ttgaaatgaa
     6241 gggggttact tgaaggcatt aaaccgactt tatccggtgc aataatatat acggcctcca
     6301 ctaataaacc catttccttt gcagtacgct catttaatcc cgtagacgct gctgcatagt
     6361 caaaaacttg aatgcttgat gatccgatga cacctttatt taagaccgga attccataca
     6421 tatgatctgc taccgcacgt gcctgacgtt gagcaggacc agcaagagct aaacgcgttt
     6481 gtttgttcat cagacggtga tacacctcga tggcatcgcc aactgcataa atattcgggt
     6541 cgcttgtttg gtaattttga ttaactttaa ttgcaccctt ttctccaatt tctaagcctg
     6601 cttctgtagc taaagtagtt tccgggcgta caccaattgc taaaacgaca atgtcagcag
     6661 cgacttcttt acctgaattt aacttaatca aattcggcgt gatttctgct aagccatcac
     6721 cgacgattaa ctcgacacct tgatcaacca tttctttgtg taaaatttgc gccatgtcgt
     6781 catcaaacgg tgttaaaatt tgtggtgcaa attcgacaag cgatacattt ctacctgcta
     6841 aacgtagatt ttccgctact tccactccga taaatcctcc accaattacc gcaatgtttt
     6901 gggcgtcatt ttctacaatt gcattatgta aacgctcaat atccacaaca tttcttacgg
     6961 taaatacatg aggcaggtcg ttacccggca atttcggtac gattggactc gcacccggag
     7021 ataacactaa ttgatcgtag ctttctgttg ttcgttcgcc tgtaacggta ttttttactg
     7081 tcaccatctt gtctgcacga ttaatagcaa taacctcact attaatgcgg gcatcaatgt
     7141 tatgcttagc ttcaaatgaa tccggtgtca tcattaacag cttcttgcta tctgcaacaa
     7201 ctccacttaa ataaaacggt aatgaacaat tcgaaaatga tacatgtggt cctttttcaa
     7261 acatcacaat ttctgcctgc tcgtctaaac gacgaatcct tgctgctgca gaagcaccgc
     7321 ctgcaacccc accaataatg actacttttt tcatcttgaa ccctcccata aattacacta
     7381 actatgtttt ttcttcttat ccacatatta tacccctgta ggtataatgt caattttttt
     7441 atgacgaata ttaccttact tgtagctttt taatagatgt tccaatcaca cacctaaata
     7501 aaaagacgac cgacaagttg attgtcgatc gtccaaacta atccgtaaat aataaccgta
     7561 tagacaatga cgatatttta gtaaatataa ggtaatttat tttttcttaa tttttaaaaa
     7621 tataaaaggc taacattgct attaacaagc gaagctagcc cttttttgtt ctgttatagg
     7681 attatactgg actgacacca tgcttgcgtt ctgtgaatgt cagatttttt gttttgtacg
     7741 cttcgaggcg aatctccaat gtcttgcgca gttcgttcgg ttcaatcaca tcatcaatga
     7801 ttaactccga tgccagacga tacacatcga tttcttcctg gtactcttcc cgcttctgat
     7861 cgataaatgc ggcctgctct tcttttggca aagctgcaat tttatttgca tataccgcat
     7921 tgatagctgc ttccggtccc attacagcga tttgtgcacc tgttaaagca atgcatacat
     7981 ctggttcaaa tgctggaccc gccattgcat aaagtcccgc accataggcc ttgcggacaa
     8041 taaccgtgat tttcggtact gtcgcttcac tcatcgcata aatcattttc gcgccatgac
     8101 gaataattcc catcttctca acatttgtac caatcataaa tccaggcacg tctgctagga
     8161 aaattaacgg aatgtggaat gcatcacata agttgatgaa ttttgcagct ttatcagctg
     8221 aatcatggaa taacacgcca cctttaacgc gcggttgatt ggcgataata ccgacagatt
     8281 ggccattaat acgcccaaag cctgtaatga tttcaggagc aaatagcttt ttcacctcac
     8341 agaatgagcc ttcgtcaata atacggtcaa ttaaatcata catattgaac ggtgcatttt
     8401 ggtttgcagg gatgatttcc tcaatcgact tttcaaacgt tttcggcaat tttggctctt
     8461 ccacattcgg cttgttttta aagttatctg ggaaatagct gatgtattgt cttgcgtaag
     8521 caattgcctc ttcctctgtt ttcgctagta catcaccaca acctgaaact gaacagtgca
     8581 tttttgcccc acccatcgtt tcaagatcga ccttttcccc tatgaccatc tccgccatac
     8641 gcggtgatcc taagtacatg gaagcattcc cttccaccat aactactaca tcacagaatg
     8701 cgggaatata cgcaccacct gctgctgaag gtccgaataa tagacaaatt tgcggaatac
     8761 ggccagataa tttgacctga ttgtaaaaga tgcggcctgc tcctcggcgg ccggggaaca
     8821 tctccagttg atccgtaata cgggcacctg atgagtctac taaataaagt agcgggacat
     8881 taagtttttc agccgtctcc tgaatacgga taattttctc aaccgttagc tttccccaag
     8941 agcccgcttt tactgttgag tcatttgcca ttacacatac agttcgccca tgaattttcc
     9001 cgatccctgt gacaacgccg tctgcaggta ggtcacctgc aagtacatta gcaaacgttc
     9061 catcctctgc ctgtaaccct tcatcaaaga ggagctccaa acgctctcga acaaataatt
     9121 ttccttgttc ctgatttttt tcatgatact tttcatgacc gccctttaac acattattct
     9181 tcatttcttg gtgtttgttt tcaactgtca attttgtcat ttcttccatc ctccttttat
     9241 ttgcctctgt aagctggtgg tcgtttttct tggaaagcct tcaatccttc tatccggtct
     9301 tccgtttgta gtaatcggct atatgccaat gattcgattt ggagtccggt agaaatatct
     9361 gtctgcatcc cctgattgat cgccgttttt gcctgtatga gtgaaagtgg tgcatttttg
     9421 gcgatttcgt acgcaagctc cttggcctgt tcaagcaatt tttctggctg ggtaatgtgc
     9481 tcaatcatcc cgtactgata cgcttcctcc gctgtcagac gacgggcagt gtaaattagc
     9541 tcttttgcct ttcctatacc aattagacga ggaagacgct gtgtcccgcc tgctcctgga
     9601 ataatgccaa gtgctgtttc agtcaagccc atttttgccg tattgctagc tatacgaata
     9661 tcacatgcaa gtgctagctc cagacctcct ccaaacgcaa caccattaat agcagcgata
     9721 actggctggg caagcgcttc aaaatgattc atcgtctttc caattagtgc aatggttttt
     9781 cgagtttctc cctcattcat ccctttacgt tcctttaggt cggctccagc acagaaggcc
     9841 ttttctccgt ccccggtaac aataacaaca cggatagaac gatcatcgtg aattgcttct
     9901 agtgcctcat tgatttcatg taacatttga acagatagcg cattagcggc ctccgctctc
     9961 ataaacgtga ccactgctac cccgtcttgc acctctactt ttacgaaatt tggcatgatt
    10021 ccccctcctc tcttgcaata gcaactagct ttgaagatag tgttttgccg attattccct
    10081 cgacataaag ggctgtttgc tggatttttt ccaagctgac acctgtttcg atgcccatct
    10141 catgcaagaa atacaataaa tcttcagttg ctacattgcc tgatgccccc ttagcatacg
    10201 gacatccgcc aagcccacca attgcactat caaatttcgt aattccatgt gcaagacttg
    10261 tcatgacatt agcgatggcc gtgccacgtg tatcatgaaa atgcatcgct agcttttcac
    10321 ctttgaagtg acgcagcatt tcatgaagta gcgcatctac ctgtgtcggt acacccacac
    10381 ctgtcgtatc tccaagcgat agttctgaaa tgcccatatc aaacaatttt tctgccacat
    10441 ttacgacctg ctccggcttt gtatagccgt cataggggca tgcaatgacc gtagagatat
    10501 aacctcgtac ggtcttgcct gctgctagtg caccatccac aacttccttt aatatcggaa
    10561 acgtctcatc aatggatttg tttatattcg atttgttgtg gccctcactt gctgacataa
    10621 aaatacttac ttcatcgaca ccgacgtcga gtgctcgtgc tagcccttta ctgttcggca
    10681 caagtgcagc atacgtaata gcgctatttc gcttaatttc ttttagaacc tctacagcgt
    10741 ctgccaactg tggaatccat ttcggatgta cgaaactcgt gacttcgatg taattgagcc
    10801 cggactcgct taaacgatta acgagctgga ttttctcttc cgtcggtata aaagtcgttt
    10861 cattttgtaa cccatcgcgt ggccctactt cttttatttg cacttgcttc ggcagttgca
    10921 tagactacac tcccttatcc gatttcaact aaatcgtttg cttcatcgat aaaatcgcct
    10981 tcagctacaa tgattcgctt cactgtccct gcttcttcag ttacaatagg aatctccatt
    11041 ttcatagatt ccaaaatagc aacatcttga cctgctgtta cttgttcgcc ttctttcact
    11101 aaaatcttcc atactgttcc tgccatactc gcttttacta ttgtcatata ttattcctcc
    11161 atttaatata aagtgtagag aagtggcacg cagtagatac gatctcgcca aagttcaatc
    11221 ttttgcgcct cttctcctct tatttaccga ctgcttttgt ttttggtaaa tagtattcct
    11281 ccacaaactt agttgtagtg ctacctgcta aaaattgctc atgtgtgaca gtttcaagca
    11341 gcatcggtat attcgtttga ataccttcca ctacataact gcgcaatgca tcggctaacc
    11401 ttacacatgc ttcctctcgt gttgaaccaa acacaacaag ctttccaatc attggatcat
    11461 aaaaaggagt tacctcgctt cctgtttcca cagctacctc atgtcgaatc ccttctcctt
    11521 caggtaatac tagtttcgta attttccctg gtgacgggaa gaaggttacg ggatgttccg
    11581 cataaatacg cacctcaatc gcgtgccctt tttgttgaat atcctctctt gtaaaggcaa
    11641 gcttttcgcc atttgctatc ttcaactgct gctcaacaag atccagtcct gtaatctctt
    11701 ctgttaccgg atgttccacc tgtaagcggg tattcatctc taggaagtag aagttttgat
    11761 cacagtccac taaaaactca atcgtgccag catttgtgta gccaatatgt tttgctgcat
    11821 tcactgcggc atctaacatt ttcttacgtg tctcttctga tatgaacgga gaaggagctt
    11881 cctctaccac tttctgattg cgacgctgta tagaacattc acgctcatag acgggaataa
    11941 cgctgccaaa tgcatcagct agcacctgca cttcaatatg atggggttct gcaatgaatt
    12001 tttcgataaa catcgtcccg tcaccaaaga agctttgcgc acgtttttga tttccttcga
    12061 atgccttacg cagctcctgt tcattgttga ccagctgcat accgattcca ccgccacctg
    12121 cagatgcttt taacatgaca ggatacccaa tgtcctctgc aatttttgca gcttcatctg
    12181 tatcagcgat tggttcatta accccctgca caattggcac tccagcttgc tccatcgttt
    12241 ttcgtgcctc tattttgctg cccattgatt gaatgacctc aaattttggt ccgataaacg
    12301 ttaatcctgc ctcctctaca cgtttggcaa atgttgcatt ttcagataat aagccatagc
    12361 ctggatgaat ggcatcagaa cctgtttgct ttgccacatc taaaatggaa tctatattta
    12421 aatagctttg tgttactggt ggtttaccaa tacagaagct ttctgttgcc tcttttacat
    12481 gcagactgtt cgcatcagcc tccgaataaa ttgccaccgt ttcgatgcct aatcggttac
    12541 acgttctgat aatgcggcgc gcgatttcgc ctcgattggc aatgagtacc tttttgaaca
    12601 tatttcaacc tccctaatgc attgttttca ctaaacttgc aaactgttca cgaattttga
    12661 acttctgtat ttttcctgac gcggtcattg ggtaactgtc gacaaaaaag atatagcgcg
    12721 gtattttatg cctcgatatt ttccctttgc agaaatccct tatttcttct tccaccgctg
    12781 tctgcccttc tttcaggata atccatgccg ctacttcctc gccgtacttc tcatccggaa
    12841 cgccggtcac ttgtacatct agcacttttg gatgttgata aaggaattct tctatttcac
    12901 gaggatacac gttctctcca cctctaataa tcatatcctt caatcgtcct gtaacacgga
    12961 catagccatt ttcatccatc gttcctagat cgcccgtgtg cagccagtta tcggtgtcga
    13021 tcgcttcttt tgtcgcatcc ggattattgt aataaccttt catgacgaca tagccccgag
    13081 cacaaatttc tccttgctcc cctcgaggaa cctcttcatt tgtacctggc ttcataattt
    13141 tcacttccac atttggtaaa gcacggccaa ctgtctctac tttcagattc agtgggtcat
    13201 ctactcgtgt ttgtgttaac actggtgaag actcggtctg accgtagcaa atcgtcacat
    13261 cttccatacc aagtttattg atcacgtccc tcattacttc gataggacaa ttggagcctg
    13321 ccatcacacc cgttcgcaat gacgagacat caaaactcga aatattcggt aaatttaact
    13381 cactgataaa catcgttggt acgccatgga gcgccgtgca ttgctccttt tcaactgtac
    13441 gaagtacttc ctcaggatgg aactcctgca ccggtaccat cgttcctccc actgaaacga
    13501 tcgctagtgt acctattaca cagccgaagc aatggaaaaa tgggacgggg atacatagtc
    13561 gatcttcatg tgtcagcttc atgcattctg caatgttgat cgcgttgtta attagattgg
    13621 aatgccgtag catcacacct tttggaaagc ccgtcgttcc cgatgtatat tgaatattaa
    13681 tgacatcatc ataatttaag gattgtttgc gttgctctag ttgttcatct gatattcggc
    13741 tgccattcgc caaaaattcc tcgtaggtga acgtcccagg atatttttta tcactaatta
    13801 cgacaacgct ttttaaaagt ggaagtcggg tactttgtaa tttacctggc tcacattctt
    13861 tcaactctgg acataagtca tataaagtat caatgaatgc atgatcccgg tagttgtcga
    13921 ttaaaataat cgcccttgaa tcagattgct taagtaaata ttccaactcg cttgtccggt
    13981 aactcgtatt cacagtgact agcggtgcgc ccatcttccc tgacccaaat tgaagtcccg
    14041 gccactgcgg aacatttgtc gtccaaaccg agaaatgatg tcctttttca agttcaattg
    14101 ccattaacgc ttttgcgact aaatcactgt gtttgttaaa ctgggcatat gtcatgcgat
    14161 aatctcggtc tgaataaact aatgcctccc gattagggta ttgtgcagcc ttttcttcca
    14221 gtagctcgcc aatcgtttga taaacaagtt ctgccatacg cattcctccc ttttgtcaaa
    14281 aaactaacaa cctaacactc gtgaaataac tacgcgttgg atttcagatg taccttctcc
    14341 gatttccatc aatttgatgt cacgcaaatg acgttctaca tcgtactctg ccatataacc
    14401 gtaaccacca tggatttgaa tcgcctgatt acatgtacgg aagcccattt ctgacgcaaa
    14461 tagttttgcg aatgcggctt cttttttaaa tggctttcct tcatctttca gccacgctgc
    14521 cttcattacc atattgcgtg ccaattcaat ttccatcgcc atatccgcta atttaaactg
    14581 aattgcctgt aatttagaaa tcgattttcc aaactgtaca cgttccttag aatattgtag
    14641 tgctttctca aatgcggact gcgcaatgcc gaccgatagt gcagcgatgg aaatacgacc
    14701 tccatccagc gtatttaaaa attgaccaaa tccctttttt tcgtctccca acacgttttc
    14761 ttttggtact cgaacgtttt ccaaaacaat ttcacatgta ttcgatgcac gcacacccat
    14821 tttttgatat tcagaacgga tcgttacgcc tggtgtgtca gttggaacga tgattgccgt
    14881 tataatattc ttcccacgct catcttttcc cgtaacagcc gtcactacaa tttgacgggc
    14941 ataactggca ttcgtaatcc aacatttctc gccgttaatg acccactcat ttccttcgag
    15001 ataagcattt gtccgagtac cccctgcatc agatcccgca tttggctccg taagtccaaa
    15061 cgaaccgaac gtctttcctt gcgccattgg aacaaggtat tctagcttct gctcctctgt
    15121 accaaagtta taaaaagggg ttgcgcctaa gctgacagcg gctgcatagc ttaagcctgt
    15181 tcctccacat gcacgaccga tttcttccac ggctaatgca aaggaaatag tgtctccgcc
    15241 tgacccgccg tattcttcag gaaatggaat tccaaataat ccaagttctc ccatcttatc
    15301 gaagctttct tttctaaact gatgcttctc atccagctca cgtgcatgtg gagcaatttc
    15361 agcttgcgca aactcacgta ccatatcacg aatcatttct tgttctttag ataattcaaa
    15421 attcattttt aaagccccct tagtttttgg attaaagacc gactagtcgg tttgtattat
    15481 tttaaaaaaa accagacttt taattgcctg actgttacta aatttacata atgtactttt
    15541 tcgctttagc ttcctcaaga ccttgctctg tcagaacacc tcggagaatc aaatcattga
    15601 aatgatgtgt aatctgctcc atcgttaagc taccgttctg ccggtaccat ttatatgtcc
    15661 agttcaccaa tcctatgatt gccattgtcg taattgtagt agaaatctcg ggtcgaaatt
    15721 gtccaccctc ttttccctcc tctatcacct gctcaatcaa cttttggtat tccttccgct
    15781 tttctttgat gatattttta tattctagag gtaaataagc gctttcatta tagaacaccg
    15841 taatatgacg ttgataaaca tcaaatacat tggtaaatgc aaataacaga gcagtcactt
    15901 tatcgattgg cgtatcattt tcttcatagg ctttttttgt ttcttttaat acgtgggaga
    15961 tgaacaaatc atgtatctca tataacaagg catccttcga tttaaattta tgataaaatc
    16021 cgcccttaga tgttccagct gtttccacaa tttcatccac tgatacaccg tggtagccct
    16081 tgtgcctaaa aaggtcaagt gctgtttcaa taatccgttc ttttagcgat ttcacaacca
    16141 acttctcgcc tcccatcaat catccgttaa aattaagatg attttctgcg aaaatactca
    16201 tattttctgt taatcttctt atttttgtat gattatagca ttcttcgatt tcatcgtcta
    16261 ttatttattt gcaaaatttt atcgaaaata caatttttat ctacttcaag tatattttat
    16321 tagattttca gaaaccaaga agtcagcttc cgttttctct cttatttcct ctacagaaac
    16381 gccggatgct aattctatca gaaccattcc tttttcggta aaatcaaaga cagccaattc
    16441 cgtaatgaga cgatgaacaa cttttttccc agtcagtggc aacgtacatt ccttcttaat
    16501 ctttgattct ccgtatttcg atacatgctc catgataacg ataactcgct tcgctccttg
    16561 cacaagatcc atagcgccac ccataccctt gaccattttt cctggaatca tccagttcgc
    16621 taaatcacct ttctcagaca cttccatgcc tccaaggata gcgacgtcga tatgtccacc
    16681 acgaatcatg gcaaaacttt cagcgctatc gaagaaggat gcgccgggta ccgctgttac
    16741 agtctctttt cctgcattga ttaaatcagg atctacttcg ctttcatccg gatatggccc
    16801 aatacctaac agtccgtttt ctgattgcaa tagcacctga taatcactcg gaatttcatt
    16861 tgcaactaaa gtcggcatac caataccgag gttgacgttc atgccgtttc tgatttcctt
    16921 taccgctcgt ttaacaatcc gctcttttac actcatccaa tagcctcctc tacttttatt
    16981 gtgcgttttt caattttctt ttcgtagcct tcacctagaa ttacatgttg aacgaatacg
    17041 gctggcgtat ggatttcatc ggggttcagt tccccaactt cgacgatttc ctcaacttca
    17101 gcaattgtaa ttttccctgc agtagccata attggattaa aatttcgggc cgttttacga
    17161 tagacaagat tccctagttt gtcagccttc catgctttta caaaggcata atcccctaca
    17221 attgcacgtt cctcaatata ctctttgccg tcaaattcct taaccggttt tccctctgca
    17281 atgagtgtcc ccactccagt agctgtgtaa aacgccggga taccagcacc gcctgctcgg
    17341 atacgctctg ccaatgtccc ttgaggcgtc agttcaactt ctagctctcc gcttaaaaat
    17401 tgttgctcaa aagtcttatt ttcccctaca taagatgcaa tcattttttt gatttgcttg
    17461 ttcgctagta ataatccaag cccccaatcg tcaacaccgc aattattgct gacaaccgtc
    17521 aaatctttga tgcctttttg acgaatagcc tcgattgcta gttcaggaat accacaaagt
    17581 ccgaatccac cgactaatat ggttgcacca tcttgcactt ctccgacaat tccatgtatg
    17641 tttttctcta ctttatgcac aatattcctc ctttaagtaa aattaacatc attataaaca
    17701 ggttatttta gaatagcaaa ttaaaattct gaattttcta atacgaagaa tgctagttta
    17761 aaagctagcc ctgttttatt gacagcacgc tcataacatt ttactttttt ctcctaagtc
    17821 agtaaaaaac cccgtcaatc aacattgatt aacgaggttg gatactatta attacgcagc
    17881 atgtaaaatt aacatcttaa agcttaaatt aaagaagtta aatttaagtc agcctctgtg
    17941 cacggttata tataaaaata ctacataaca tgattaagga aataattgca aacatataat
    18001 tgattgaagc tgttaataac cagcctccca gtattgggcc gataaagccg ccaatatttt
    18061 taaactggga agcaccaaga tatgttccct tttgatcttc cggtgcaatt tcttctatca
    18121 ctgcattcat cataggaaaa cagaaaattt caccgaccga aaacacaatc atactcgcga
    18181 tgaacatcca cgaactatcg gaaacaccaa acaaaaataa cccgactgca aagatgacta
    18241 cgcctatttt tagcgaagaa taaatcgaaa ttctctcact tactacggtt aaaggcagct
    18301 gaaatgctaa taccgttatg gagttcgcga cgatcacata agaaaacagc ttcaccccat
    18361 cttccacatt catgttaata aattgcggta gtgtcgagtt aaactgggaa tagccaactg
    18421 taattaaaat gcctcctgcg ataaacagca atagcttttg atcatgaaaa accgcgctca
    18481 aaatcgttct aatttgatgc tttgaactaa gtcttttttg cttcatttca tagcgattta
    18541 aaacaatgat taaaaataaa ccatataacg catacataaa gcctgtaatc ataaacggtg
    18601 ttgccggact tgccaagcta gcgacccata ctccaagcag tggacccata acagccgcaa
    18661 tattaattgc cgtatagcgt acggaaaaga ggcgcctttt tttagcatcc tccgtaaaat
    18721 caatcattaa tgcttgtgta cctggttcaa aaaatgagcg acataatcca ttaactgcat
    18781 tcaacaaaac gaaataaaca gcagaaggag ccaatgcaaa accaacgaat gtgaggctcc
    18841 atataaagac ggtaataata ataactgctt ttcgtccaaa acgatcggtt aaatacccgc
    18901 cgattaagcc gccaaacgtt gaaaataacg gggctattcc aattgtcaca ccgattaaca
    18961 aaggagaggc ttgaagttca ttatgtaaat ataaagctaa aaacgggata gccataaaac
    19021 tggctgttcg aacaaaaatt gttccgctta atatgatcca tacaagtgga tggaaatatt
    19081 gaaaaattct ttgcatacat tgtctcctct agtttttcat tggatgtaat ttccattata
    19141 cataacttcc gtaaataata tttcactaat gtgaattttc aatattttat ctcttcattt
    19201 ccagtaaaat ggtataattg cagaaaataa taggttagga gggaaattca agtgaaactt
    19261 acgaaagaag agaaatcgtg gatattgtat gattgtggga attcagctta ttcaatagcc
    19321 attacaactg ccctgtttcc aattgtcttt ggtatgttta atggggtaaa taatatggac
    19381 ttggggtact ttaattcact tgccagtata tttgttgctg tacttagccc cattttagga
    19441 gcatttgcag attacaaaga taagaaaaaa cgtttcttca ccttttttgc attagtcggt
    19501 attatttcta ctctttcctt tacatttatt tcacctgaaa gtggacaatg gcagctatta
    19561 attgtcatgt acattttatc ctgcattggt tttgccggag caaatatttt ctatgattct
    19621 ttcttagttg atgttacgac agatgaaaag atggataaag tatcctcatc cggttttgca
    19681 ttcggctaca tttcaagcgt catccctttt ggaattagtt tagccgttat tttcgtaatg
    19741 ggaatggatg aagcgattgg ctatcaaatc ggtttttgta ttacagcatt atggtgggga
    19801 ttactgacaa tcccgatgat tcgtgatgtg aagcagcgtc attatatcga accagaacca
    19861 aatccggttg gtaacagctt taaacgatta ggtcagacgt ttttaaacat taaagattat
    19921 aaaatcgtat tcttattttt aatcgcctat ttctgctata tcgatggagt cgatacgatt
    19981 attaaaatgg tagtacctta tgcaacgagc gttttaggac cagatagttt aaatacattt
    20041 atgctattag gaattttact cgtcattcaa attgttgctt ttccatttgc ccttctctat
    20101 ggttctcttg ctaaaaaata ttccacacgc tcgatgatta ttgccggtat tacgacatat
    20161 atggttgtat gtattgcggc atttttcata tctgaaatgt ggcatatctt tgtgcttggg
    20221 attatgattg gctctgcgca aggcggaatt caggccctta gccgatcgta ctatggaaaa
    20281 attataccga aagaacgatc gaacgaattt ttcggctttt ataatatttt cggcaagttc
    20341 gctgcgatta tcggtccctt tttaatggca ttgacaacta cattaacagg tgaagcaaga
    20401 tatagtattt tatcaattat tccattattt attatcggtc tcatcgtatt cctcatgctt
    20461 ccaaaagatg taggtcaaca aacaagaaca gtaaggtgat tatatgacac aaaaaagtaa
    20521 atatgtcatc gtcgtttcgt acgacgcttt ttccatcgat aactgggaaa gcgcaaagtc
    20581 gaaatcgaat ttggcaaagt taattgaaaa tggtgcttcc acaaatttag taaaaagtgt
    20641 gtatccgacc ctcacctatg ttattcacag ttcgtatgtg acgggtatgt atccagataa
    20701 acacggtgta tttcataata atccgttcca gcctttcgtg cctgaaagcg aacaaaactg
    20761 gcattggttc aggaaggata ttcaagcgcc aactgtgtat gaggccgctc ataaaaaggg
    20821 tcttacaaca gcaggattat tatggccagt aacaggaaaa gcacaaatca attacaatat
    20881 tcctgaaatt aaagcagtca aaaatgaaaa ccaggcatta aagattttga aaagcggaag
    20941 taaattattc acgctccaga tggaattaaa atacggcaaa atcagacaag gaattaacca
    21001 acctaatttg gatgacttca caacagtttg tgcagtcgat acaattaaaa agaaaaagcc
    21061 caatttactg cttatgcatt taatcgattt ggatgattca aagcacttgc acggtacaca
    21121 aggggcacat attgaacaag tcatcgatcg tatggatcgg cgtatcggtg atttagttca
    21181 ggcgacaaaa gatgccggca tttatgatga aacgactttt ataattgttg gggatcatag
    21241 ccagcttgat gttcaatata aagtgtattt aaatcggtta ttttatgaag agggtctaat
    21301 ttatgagcag catggagcat ggcattggcg tgcctatgtg caaggtgctg gtggcgctgc
    21361 ctatttgcat gtgcaaccag gagattccga tgcggaaaga attgctcttt ccattttaca
    21421 agatgcaaag caacatgaat cctatggcat agaagccatt ttaagtacac aagagctgaa
    21481 cgaactccat gtaaataatc aattccgttt tatgattgaa gcaaaggaag gctactcttt
    21541 tggagatgac cacttacagg aagcgattat tgatttacat gcacaaggta aaaaatacgc
    21601 aacacatggt tatttaccat ctaaagcgaa ttatacgagt aatttaatta tttcaggtaa
    21661 tcaggtcatt gccggcactg atattggtga agtaagtgtt gtcgacattg gtcctacaat
    21721 tgcacatata ttaaatcttg atttacctaa tacagatggc cgggcgttaa ccgaaatatt
    21781 taagtgatga cttctttaag ccgtttgtca ttttactgat agacggcttt tcaacttaac
    21841 caaaattgcg aggtaactaa ctatatgtta ataaatgaat tcagtgataa tctctctaaa
    21901 tacaaactac cggaagaata tgacgagact tataaaaatt acacagcaga tttagatttt
    21961 atcaaggctc atttaggaga aaacaagagc gccattattg aacttgcttg tggtacagga
    22021 cgcttggcca tcccattagc aaaaaaaggt catatggttt atggtgttga tattgatcaa
    22081 ggtatgctgg atttcgcacg gaaaaaggcc cttagcgaag atgttgatat tcatttgagt
    22141 gtacaagact gcacacaatt gaacttaccg attacatcca attttattta tatgaccggt
    22201 aattcatttc aacatttctt aacgaatgaa agccaggatg ctctttttat atcagtcaaa
    22261 aagcatttaa acccaggtgg cgaatttcta tttgatacgc gaaatccgat tctccatgaa
    22321 cttgcgaaag acgaaattta tgaggaatct atagagaaaa atggtgaaac attcaccgtc
    22381 gtaaatcagg aaaagtatga tccattaaca caagttttac attgtacttc cacctataaa
    22441 tctacacaaa acgaatatgt agatagtatt aatttaagat atacatatcc aatagaaatg
    22501 aaacggcttt tagagcagca tggatttgaa ctgattcatc tttatggttc ctggacaaaa
    22561 gcaagcttta atgcaaatag catttcgatg gtgattcatg caaagttaaa ggaagtttaa
    22621 tacgggtgcc taaaccatta ttctccttgg gggaaatgga tttttttcgc tggcataaaa
    22681 aatttattat cattccggga cgctatccgc gggcacggct ttacacgaac gtctcaggcg
    22741 tcggtgctcc tgcgattact cgtcgcataa ataattgctc ctgcgattac tcgtcgcata
    22801 aataattgct cctgcggtta ctcgtcgcat aaataattgc tcctgcggtt actcgtcgca
    22861 aaataaattt tgctgttccc gcaggaagct ttgcttgtag cgaaaggcgt tagccgtcag
    22921 ctatactcgc cctccattcc aatcaatttt taaagtatcc gttttttaat tggtgctgtt
    22981 aaaaaaaatt tgaattatat attcctcaaa taaagtttaa taattaggac tcacaaagac
    23041 tattgcatct gactttaatc tcctcgggta ttatttaagc gatgattcta caattaatag
    23101 catcctctac gtgtttagga atctctatac gtctgctatt ttctaaatat cagagcgcaa
    23161 attaattttt acagccactc aataataggt ggagtaaacg tttcgggaat cattggagaa
    23221 ggcaaacttc cagtatgatt tgttaaacca aatgacgcac catctatatc aatccaatct
    23281 tattctctaa cattagggat ttcgccaata aaatgatagt cattacgcat cacgcgcata
    23341 ggtttcttcc attgcatcaa acacggttcc gtctcgaaaa tctgctcgat ccatctgtaa
    23401 tcgctcgcat acggcatata aaaaccaaag ccattgttca tcctgctcta tcattgcttg
    23461 ctttccaccc gcttctaaaa atggtgtgac gatttgcttt tcaagtgttt gaaaatattg
    23521 tacggcgtct tctgcccctg gccagttcaa atcttgaaac agttcgacca tgtttggaaa
    23581 agccgcgata ttgtaagggt aaccgatttc catcacgact tttacgctat tttgccagta
    23641 gctttttccg tacgttggaa aaacgctggc cagttggttg agtggcatat ttgcgacgag
    23701 ccagtttatt gcgtcctgct gtgtctcttc tggtaaatgc caatgcaatt cattaacgta
    23761 atgctttatt tcctctcgat tcatgttgtc atctcctcgt attctagatg cccatgctgc
    23821 gggcatccaa atagctgaca tccaccgtct gggtacatat catattcaaa tggcggcaca
    23881 acaccttgtt caagtcgtaa aagcagcatt tcaagcactt tgagctgctt attacactca
    23941 attaggcact catcacggtc ctgcgccgac cagtgctcat ctagctctct ttgtcgctcc
    24001 tctacgattt cttctttttt ctgctgaatt gcttgaagaa tgaccttttg gcaagttttg
    24061 aaatcttcca gttgccagag cgtatatgca tagcgactca caatataggg cgtcacataa
    24121 tattggttcc actctttttc aaattgcaca cgtgcctcag caaagcagcc taactcgata
    24181 tacacatcag ccatttcaat tgcacccgta taatcactcg attcctcatt ccaattgtct
    24241 aaaagtgcct tggcctt
//
