LOCUS       NZ_AP023440            31868 bp    DNA     linear   CON 26-MAY-2024
DEFINITION  Streptomyces aurantiacus strain JCM 4677 chromosome.
ACCESSION   NZ_AP023440
VERSION     NZ_AP023440.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces aurantiacus
  ORGANISM  Streptomyces aurantiacus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 9428393)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye
            Genome Coverage                   :: 62X
            Sequencing Technology :: Illumina HiSeq X Ten; PacBio Sequel II
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014701115.1-RS_2024_05_26
            Annotation Date                   :: 05/26/2024 05:58:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,211
            CDSs (total)                      :: 8,122
            Genes (coding)                    :: 7,928
            CDSs (with protein)               :: 7,928
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 194
            CDSs (without protein)            :: 194
            Pseudo Genes (ambiguous residues) :: 0 of 194
            Pseudo Genes (frameshifted)       :: 69 of 194
            Pseudo Genes (incomplete)         :: 161 of 194
            Pseudo Genes (internal stop)      :: 17 of 194
            Pseudo Genes (multiple problems)  :: 48 of 194
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:48:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8647927
            Orig. end                         :: 8679795
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP023440.1.
            Genome sequencing and analysis were conducted under the Global
            Catalogue of Microorganisms (GCM) 10K type strain sequencing
            project (http://gctype.wdcm.org). The genomic data are also
            available at http://gctype.wdcm.org/sequencing/GCM10017557
            Annotated by DFAST v.1.2.7 (https://dfast.nig.ac.jp).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..31868
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /region_number="30"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..31868
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..31868
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:17868](-)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(14001..17868)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     misc_feature    533..548
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.23"
                     /tool="antismash"
     gene            568..2562
                     /locus_tag="IGS71_RS37290"
                     /old_locus_tag="GCM10017557_76080"
     CDS             568..2562
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603521.1"
                     /locus_tag="IGS71_RS37290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_76080"
                     /product="sulfatase"
                     /protein_id="WP_190854326.1"
                     /transl_table=11
                     /translation="MSSTTNSHQLPDTDRATPEEPATPEALPPADSTPTEKPGTPAGTT
                     DAATAEPDASADGGATSAESEAEGEHEVEAEDENVPTDDLKGSPNSPDTGLPDDKDPSA
                     DDGAVGDEPPAPKGWRAKYPVAARTVTWTITVLAALLVLFALLMPNEIDRFRPGVFFRL
                     PVEAIFGAAVLMVLPKTLRLVAAVLAGLGLGALTVLNLLDLGFNEFLGRGFNVVLDWIL
                     FDDARTYLEDSMGKAGAVGVVIAVIALVVAVFALMVLSVVRLANLLARHSGRATRATLI
                     AGTVWVACSALGVQFTGVQFASRSAAGAVQNRVDRVQATLKDEAEFAKVAKKDTFANTP
                     ADQLLTDLRGKDVIFGFIESYGRSAIEDPVMAPGVDATLTDKTEELSKAGYSAKSGWLT
                     SATYGGSSWLGHSTFLSGLWISNQARYRTVTAGEHLTLTGAFQRTGAWRTVGIMPGVQK
                     NWPEASFYGLDNVYDSRELGYEGPKFSWSTMPDQYALSAYQRLEHGKKRDKPLMSEIIL
                     TSSHQPWAPIPKTIPWDEVGDGSVYKDIQKDGKKASDVFYDSTKVKEEYGKSIEYSVTS
                     LIDYVVKYGNKNTVLVFLGDHQPLARVSGNHASRDVPISIVAHDKSVLDKIDDWGWTEG
                     LKPDDTAPVWRMDSFRDRFLTAYGSTPRP"
     gene            complement(2646..3941)
                     /gene="paaK"
                     /locus_tag="IGS71_RS37295"
                     /old_locus_tag="GCM10017557_76090"
     CDS             complement(2646..3941)
                     /EC_number="6.2.1.30"
                     /GO_function="GO:0047475 - phenylacetate-CoA ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (85-335). E-value: 1.3e-22.
                     Score: 71.9. Matches aSDomain:
                     nrpspksdomains_IGS71_RS37295_AMP-binding.1"
                     /codon_start=1
                     /gene="paaK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007503538.1"
                     /locus_tag="IGS71_RS37295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_76090"
                     /product="phenylacetate--CoA ligase PaaK"
                     /protein_id="WP_190854327.1"
                     /sec_met_domain="AMP-binding (E-value: 3.2e-27, bitscore:
                     94.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANSTDLLDAGERLDADGLRALQLERLRATLRHAYENVPFYRDSF
                     DKAGLRPEDCGSLADLARFPFTTKADLRDNYPYGMFAAPRDRIRRIHASSGTTGLPTVV
                     GYTENDLSMWSDMVARSIRAAGGRPGDTAHVAYGYGLFTGGLGAHYGAERLGCTVIPAS
                     GGMTARQVQLIQDLRPGIIMVTPSYMLTILDEFERQGVDPRHTSLRVGIFGAEPWTEEM
                     RREIEERFAIDAVDIYGLSEVIGPGVAQECVETKDGLHIWEDHFYPEVVDPLTGEVLPD
                     GAEGELVFTSLTKEAMPVVRYRTRDLTRLLPGTARVFRRMQKITGRSDDLVIVRGVNLF
                     PTQIEEIVLRTPGVAPHFQLRLTREGRLDALTVRAEARTGATPEIRDAAARAIATAVKD
                     GIGVSARVEIVEPESLERSVGKIRRIVDLRPR"
     CDS_motif       complement(2907..2969)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IGS71_RS37295_0001"
                     /evalue="4.10E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="IGS71_RS37295"
                     /protein_end="345"
                     /protein_start="324"
                     /score="13.2"
                     /tool="antismash"
                     /translation="TGRSDDLVIVRGVNLFPTQIE"
     aSDomain        complement(2937..3686)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IGS71_RS37295_AMP-binding.1"
                     /evalue="1.30E-22"
                     /label="IGS71_RS37295_AMP-binding.1"
                     /locus_tag="IGS71_RS37295"
                     /protein_end="335"
                     /protein_start="85"
                     /score="71.9"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DRIRRIHASSGTTGLPTVVGYTENDLSMWSDMVARSIRAAGGRPG
                     DTAHVAYGYGLFTGGLGAHYGAERLGCTVIPASGGMTARQVQLIQDLRPGIIMVTPSYM
                     LTILDEFERQGVDPRHTSLRVGIFGAEPWTEEMRREIEERFAIDAVDIYGLSEVIGPGV
                     AQECVETKDGLHIWEDHFYPEVVDPLTGEVLPDGAEGELVFTSLTKEAMPVVRYRTRDL
                     TRLLPGTARVFRRMQKITGRSDDLVIVR"
     gene            4125..4604
                     /locus_tag="IGS71_RS37300"
                     /old_locus_tag="GCM10017557_76100"
     CDS             4125..4604
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003991797.1"
                     /locus_tag="IGS71_RS37300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_76100"
                     /product="hypothetical protein"
                     /protein_id="WP_190854328.1"
                     /transl_table=11
                     /translation="MSRTGKRAAGVGGLVAVLAAACLGWAVWAVASSERHVGEDARAGD
                     ARSRAVQVPCREALRFADQERLPAGAKDAACVMQHGIDTLYDVGFRISRTGLDAWLADT
                     YPDMKLDSTCVEDDADRCGHLDLHPYAEGGAVALELTVRDESDGSALVHFKPFNT"
     misc_feature    4299..4301
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4655..6301)
                     /locus_tag="IGS71_RS37305"
                     /old_locus_tag="GCM10017557_76110"
     CDS             complement(4655..6301)
                     /NRPS_PKS="Domain: AMP-binding (8-438). E-value: 2.2e-69.
                     Score: 225.9. Matches aSDomain:
                     nrpspksdomains_IGS71_RS37305_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662883.1"
                     /locus_tag="IGS71_RS37305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_76110"
                     /product="acyl-CoA synthetase"
                     /protein_id="WP_190854329.1"
                     /sec_met_domain="AMP-binding (E-value: 6.1e-74, bitscore:
                     247.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYNLADLFESVVDVVPDREALVHIDHPGTGAERRLTYAELDAAA
                     NRVAHHLLAGGIRPGEHLGLHLYNGIEYLQTVLGCLKARIVPVNVNYRYVEEELIYIYR
                     DADLVALVFDAEFTGRVAAALPRASALRHLVRVGVPAPDAPALPAVDFADAEAAGAPGR
                     GFPARSADDQFIIYTGGTTGMPKGVMWRQEDLFFAGLGGGAPTGEPVKSPEELAERVAA
                     GGDGITFFPTPPLMHGTSTLTAFIGFHFGQRVVIHRKFVPEQVLRTIEKEKVTSVSLVG
                     DAMLRPLIDALNGPMKGTDCSSLFSVSSSGAIMSETVRAQFQALVPNVLLLNNFGSSES
                     GFNGTATADSGPDRGFRIEVNSRTRVVDPATHEPVAVGEPGRIAQRGHVPLGYYNDPRK
                     TAETFFQKDGERWVLLGDMATVDEEGVVTVLGRGSQCINTGGEKVYPEEVEQALKSHPD
                     VYDALVAGVPDETWGTHVAAVVQLREGGGRPSLHDIQTHCRTHLAGYKIPRRLVITEAI
                     QRSPSGKADYRWARSVAAEAEAEAEAGAAPE"
     aSDomain        complement(4988..6277)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IGS71_RS37305_AMP-binding.1"
                     /evalue="2.20E-69"
                     /label="IGS71_RS37305_AMP-binding.1"
                     /locus_tag="IGS71_RS37305"
                     /protein_end="438"
                     /protein_start="8"
                     /score="225.9"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FESVVDVVPDREALVHIDHPGTGAERRLTYAELDAAANRVAHHLL
                     AGGIRPGEHLGLHLYNGIEYLQTVLGCLKARIVPVNVNYRYVEEELIYIYRDADLVALV
                     FDAEFTGRVAAALPRASALRHLVRVGVPAPDAPALPAVDFADAEAAGAPGRGFPARSAD
                     DQFIIYTGGTTGMPKGVMWRQEDLFFAGLGGGAPTGEPVKSPEELAERVAAGGDGITFF
                     PTPPLMHGTSTLTAFIGFHFGQRVVIHRKFVPEQVLRTIEKEKVTSVSLVGDAMLRPLI
                     DALNGPMKGTDCSSLFSVSSSGAIMSETVRAQFQALVPNVLLLNNFGSSESGFNGTATA
                     DSGPDRGFRIEVNSRTRVVDPATHEPVAVGEPGRIAQRGHVPLGYYNDPRKTAETFFQK
                     DGERWVLLGDMATVDEEGVVTVLGRGSQCIN"
     CDS_motif       complement(5090..5137)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IGS71_RS37305_0002"
                     /evalue="2.00E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="IGS71_RS37305"
                     /protein_end="404"
                     /protein_start="388"
                     /score="13.8"
                     /tool="antismash"
                     /translation="VPLGYYNDPRKTAETF"
     CDS_motif       complement(5732..5782)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IGS71_RS37305_0001"
                     /evalue="3.10E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="IGS71_RS37305"
                     /protein_end="190"
                     /protein_start="173"
                     /score="19.8"
                     /tool="antismash"
                     /translation="FIIYTGGTTGMPKGVMW"
     misc_feature    complement(6419..6434)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.83"
                     /tool="antismash"
     gene            6489..7289
                     /locus_tag="IGS71_RS37310"
                     /old_locus_tag="GCM10017557_76120"
     CDS             6489..7289
                     /NRPS_PKS="Domain: ECH (9-257). E-value: 1.2e-53. Score:
                     173.9. Matches aSDomain:
                     nrpspksdomains_IGS71_RS37310_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474402.1"
                     /locus_tag="IGS71_RS37310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_76120"
                     /product="crotonase/enoyl-CoA hydratase family protein"
                     /protein_id="WP_190854330.1"
                     /transl_table=11
                     /translation="MGGTEHLTVQREGATLVLTLNRPEAKNALSLPMLVGLYDGWVEAD
                     EDDAIRSIVLTGAGGAFCAGMDLKALAGKGMEGQEHRDRLTADPDLHWKAMLRHHRPRK
                     PVIAAVEGHCVAGGTEILQGTDIRVAGESATFGLFEVKRGLFPIGGSTVRLQRQIPRTH
                     ALEMLLTGRPYSAREAADVGLIGHVVPDGTALEKALAIAAQINACGPLAVEAVKASVYE
                     TADMAESDGLAAELKRGWPVFDTADAKEGARAFSERRAAVYRRE"
     aSDomain        6516..7259
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IGS71_RS37310_ECH.1"
                     /evalue="1.20E-53"
                     /label="IGS71_RS37310_ECH.1"
                     /locus_tag="IGS71_RS37310"
                     /protein_end="257"
                     /protein_start="9"
                     /score="173.9"
                     /tool="antismash"
                     /translation="QREGATLVLTLNRPEAKNALSLPMLVGLYDGWVEADEDDAIRSIV
                     LTGAGGAFCAGMDLKALAGKGMEGQEHRDRLTADPDLHWKAMLRHHRPRKPVIAAVEGH
                     CVAGGTEILQGTDIRVAGESATFGLFEVKRGLFPIGGSTVRLQRQIPRTHALEMLLTGR
                     PYSAREAADVGLIGHVVPDGTALEKALAIAAQINACGPLAVEAVKASVYETADMAESDG
                     LAAELKRGWPVFDTADAKEGARAFSE"
     misc_feature    7351..7367
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.77"
                     /tool="antismash"
     gene            7396..8385
                     /locus_tag="IGS71_RS37315"
                     /old_locus_tag="GCM10017557_76130"
     CDS             7396..8385
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010033030.1"
                     /locus_tag="IGS71_RS37315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_76130"
                     /product="OB-fold nucleic acid binding domain-containing
                     protein"
                     /protein_id="WP_190854331.1"
                     /transl_table=11
                     /translation="MTEVLKAPLVVEFPFTRSLGPVQSAFLTGLRERVVLGVRTGDGRV
                     LVPPVEYDPVTSEEIGELVEVATTGTVTTWAWNHEPRRGQPLDTPFAWVLVRLDGADTA
                     LLHALDAPGGPDSVRTGTRVRVRWAEERSGAITDIACFEPYESPNPHELRDPYIGGAAA
                     LVGSDGRFEDPVTGIVAPARLDYTYSPGRAQSAYIRSLADRRVVGERCPSCRKVYVPPR
                     GACPTCGVATSEQVEVGPRGTVTTYCIVNIKATHTANLDIEVPYVYAHIALDGADLALH
                     GRIGGIPYDQVRMGLRVEPVWSEAGGHPDHYRPTGEPDADYETYKELL"
     gene            8386..9450
                     /locus_tag="IGS71_RS37320"
                     /old_locus_tag="GCM10017557_76140"
     CDS             8386..9450
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003987992.1"
                     /locus_tag="IGS71_RS37320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_76140"
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_190854332.1"
                     /transl_table=11
                     /translation="MPAPRPLRDIAVVAFAQTDHRRTSDDLSEVEMLMPVLHRVLAQTG
                     LKTSDIGFTCSGSTDYLAGRAFSFTMALDGVGAWPPISESHVEMDGAWALYEAWTKLLT
                     GDADTALVYAYGKSSPGSVRDVLTRQLDPYYVAPLWPDSIALAALQAQALIDAGDTDEP
                     ALAAVASRSRASATDNPHAQLRGSVPRGDYAVRPLRTGDCPPIGDGAAAVILAAGDRAR
                     DLCERPAWIRGIDHRIEAHGLGVRDLTDSPSTRLAAERAGAFERPLDTAELHAPFSSQE
                     VVLRKALRLDDGVDVNPSGGALAANPVMAAGLIRFGEAAARIGRGASDRALAHATSGPC
                     LQQNLVAVLEGDPR"
     gene            9447..10685
                     /locus_tag="IGS71_RS37325"
                     /old_locus_tag="GCM10017557_76150"
     CDS             9447..10685
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031483.1"
                     /locus_tag="IGS71_RS37325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_76150"
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_246596649.1"
                     /transl_table=11
                     /translation="MSDTESNALSNALSNASGNALSSATGKEPVAVVGIGQTKHVAARR
                     DVSIAGLVREAARRALADAELTWADIDAVVIGKAPDFFEGVMMPELYLADALGAVGKPM
                     LRVHTAGSVGGSTALVATNLVAGRVHGTVLTLAYEKQSESNAMWGLSLPIPFQQPLLAG
                     AGGFFAPHVRAYMRRTGAPDTVGSLVAYKDRRNALKNPYAHLHEHGITLEKVQASPMLW
                     DPIRYSETCPSSDGACAMVLTDRAGAARSPRPPAWLHGGAMRSEPTLFAGKDFVSPRAG
                     KDCAADVYRQAGIADPRRDIDAVEMYVPFSWYEPMWLENLGFADEGEGWKLTESGVTEL
                     DGDLPVNMSGGVLSTNPIGASGMIRFAEAALQVRGQAGEHQVDGARRVLGHAYGGGSQF
                     FSMWLVGAAPPTS"
     gene            10768..11010
                     /locus_tag="IGS71_RS37330"
                     /old_locus_tag="GCM10017557_76160"
     CDS             10768..11010
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003987990.1"
                     /locus_tag="IGS71_RS37330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_76160"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_055515382.1"
                     /transl_table=11
                     /translation="MAESTIQQHPLAGWDKPELDLSSADWHSSSRGLGDVQIAFVEGFI
                     AMRNSGRPEGPSLIFTPAEWGAFVSGAREGEFDLT"
     gene            11125..12036
                     /locus_tag="IGS71_RS37335"
                     /old_locus_tag="GCM10017557_76170"
     CDS             11125..12036
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971898.1"
                     /locus_tag="IGS71_RS37335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_76170"
                     /product="universal stress protein"
                     /protein_id="WP_190854333.1"
                     /transl_table=11
                     /translation="MNTLPVIAAVDGSDDSLRALDWALDAARGREAPLRVVHVREPGPW
                     LRPETLTAGRPEPDTDPVLDLVRDRLKDLARDAPVTEYVTTEYVTLDGAPAALLPGLGS
                     EAQLLVFGSRGRGGFASLLLGSNGTAAARDAECPVVVVPRPGREVHDSELVTPGPRVVV
                     GLHVDSPNNEALAFAFAEAARREARVQVAAVFPWLVQAGDLVPPPVVDEDAIESETRTL
                     ATGFVAPHAERHPGVGTDLHVLPGDAAGQLVAASRGADLVVVGRHRRRLLAPARMIGSV
                     TQAVLLHAASPVAVVPPDGTEG"
     gene            12243..12740
                     /locus_tag="IGS71_RS37340"
                     /old_locus_tag="GCM10017557_76180"
     CDS             12243..12740
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018550733.1"
                     /locus_tag="IGS71_RS37340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_76180"
                     /product="hypothetical protein"
                     /protein_id="WP_055515378.1"
                     /transl_table=11
                     /translation="MSFLRRRSATPAGPDFDVLAMDPGDWPGNLGAGLLPAPDGSCQGV
                     FLRYDLFGGRGPAMIIGNLPEGSPARDVPEGEVPFEVAQLLLALENDEEVTVAGAEDMP
                     VMQGDNLLIVRRLKLSETRISCVQFDRSDKVLVTIAAWDRPITDDLYALLKPLPAELFQ
                     QG"
     gene            complement(12679..14004)
                     /locus_tag="IGS71_RS37345"
                     /old_locus_tag="GCM10017557_76190"
     CDS             complement(12679..14004)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995636.1"
                     /locus_tag="IGS71_RS37345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_76190"
                     /product="type III PLP-dependent enzyme"
                     /protein_id="WP_190854334.1"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 6.5e-15,
                     bitscore: 54.1, seeds: 500, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 2.1e-28, bitscore:
                     98.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSPTDAVRDRVLTLASDELPAYVYDLMALRAHAAAVRDALPERV
                     ELYYAAKANPEPTILAALDPYVDGYEVASGGELAHVAEAVPGRPLAFGGPGKTPAEIVS
                     ALELGVARFHVESEYELHMLAELARQVGPEGGRVAVLPRFNLPVAAGSLAASSLTMGGR
                     PTPFGLDPSQADTVVGLLTDGTYPHLELRGVHAHLASGLRAPEQLAVAESIVGWAVRLA
                     ERHGVRLAEVNVGGGMTVDYAAPEERFDWVAYGDGLAQLCALHPDLTLRIEPGRALTAY
                     CGWYATEVLDVKHSHGEEFAVVRGGTHHLRTPAAKGHDQPRALLPVEDWPHPWPRPVAR
                     GERVTLTGQLCTPKDVLARHVLAPGLRAGDRVAFALAGAYAWNISHHDFLMHPRPGFHF
                     LDHPDHPDHPKHLDHLDHLDGRVSPAGTAPRAAASTARTGRR"
     gene            complement(14001..15977)
                     /locus_tag="IGS71_RS37350"
                     /old_locus_tag="GCM10017557_76200"
     CDS             complement(14001..15977)
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010988717.1"
                     /locus_tag="IGS71_RS37350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_76200"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_246596650.1"
                     /sec_met_domain="IucA_IucC (E-value: 2.7e-57, bitscore:
                     193.0, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDHSSLSLHLLEPHMPSLTESLGSTSLPAPSPAPGSAASTASTA
                     RTQLPSADLAVAHTLLNCLLREVSAPEQQTAVTDGRLLLRLPRRGVLLRVALRRTSMLG
                     AHRFTGPVSEQTADGGWSEVGRRRLAELTQDELYLRTGVRNEEFLEQIDSSHRTIAAAL
                     SVRTGTAPASGSVRTGAAPASVPVHAGAGPASADAPVAAYLASEQALLFGHRFHPTPKA
                     RTGDTDSWLAYAPEAAAVFPLRHLAVREHLIAEESAEPGALDVLDTFSTLDPLDPPGRQ
                     DPRKPRNRLAAGATVPEGYRLLPAHPWQYAMLGEHPTLRAALRRGDVLDLGPGGRPFAA
                     TASVRTLYDGESFLKFSLNIRITNCMRKNASYELSGAVALTRVLGPVLAGLADRFPGSA
                     VLREPAYRSLALPGPDGTPDRDLLEGFGVIVREGLARRLLPGTTPLLAAAVADEYPTSP
                     AHISRLLDGAGPRAALDWWAAYLKLLVPPVLAAYFDHGLVLEPHLQNVLICVDGDGMPA
                     QVLFRDLEGTKLVPEHHAETLASLPPDVAGPLTYDAQRGWDRVVYCLLVNHVAELLAAL
                     ADLHPHTEAALWAEVRGTLRTYADRYGCPPPLAALLAGVPLPAKANLLTRWERKADREA
                     GYVRLPSPLGEGIMRRRTTGSPR"
     gene            complement(16066..17868)
                     /locus_tag="IGS71_RS37355"
                     /old_locus_tag="GCM10017557_76210"
     CDS             complement(16066..17868)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020117198.1"
                     /locus_tag="IGS71_RS37355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_76210"
                     /product="IucA/IucC family siderophore biosynthesis
                     protein"
                     /protein_id="WP_190855857.1"
                     /sec_met_domain="IucA_IucC (E-value: 1.7e-35, bitscore:
                     121.6, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPDADTTRGELVIRVLSALLREDVVGLRSAGRLVHRPDGAWLRR
                     ATGDGQFLLLPVAEDGFQCEYAARLPLLVREPEEPSPSPSPSPAPTPLPVRYETCDTIL
                     AALRVLADPVDRAGFDAFAEECRQTLATMRLHTAAHDEVIRRLTARHGPAVTGWTGLSG
                     GTAYDTLAAHLDHPVYPTARGRVGLNESQLRAYAPELHPAFELRWLAVPRDAVTGTFPE
                     RWPTPGLLGLPELDPTHVALPVHPLTVGAPLEGVLRATGLTDRAVLADRAHLDVVPTLS
                     MRTVALTAEPSLHVKLPLDTATLGLRNRRTIKPGTLVDGAAGQRLIEQIIVREPRFRNT
                     ILHADETVYAHAGHELLAALFRRYPDGLQDSVVVPMAALLAEAPGGRLVVDHLADRFYG
                     GDLLALLDACLTLLFDWQTTLFGYGIALESHQQNISIVLDRPPHNGPTRLRLLLKDNDG
                     PRINRLRLSERLGDAAPGAGDFDDARTFGDSDRPVVDLFTTITVHLCAGAYAFGLARHG
                     RAPLPVLLRLVRDRLAEAIERLGTGAGEPGAVLRVQLLDAPRLPVKAMVTAGTLLTKER
                     SGAADINKHYTTGPNYLRLNGTSA"
     misc_feature    complement(17269..17271)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17979..19160)
                     /locus_tag="IGS71_RS37360"
                     /old_locus_tag="GCM10017557_76220"
     CDS             complement(17979..19160)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018852068.1"
                     /locus_tag="IGS71_RS37360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_76220"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_190854336.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 7.4e-06, bitscore:
                     25.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRMFLLALNPTDSVTEGFLPAAARLGVDMTVLTDQPDAHRLAYPE
                     TEVLECDVRDLRSVVTRISTLGRPDAVFTNSDHLQTQAALAADYFGLPGKDWRVALRTK
                     NKAEMRRSLASAGADTVWSAEVTDTTDVAALDVPYPCVVKPREGVASEDVVLVEGAEDL
                     VARCAEILSRRPGSALVVEEYLPGELYTLETLGDGHVRHVLGGFHTVLSPPPYFIEERL
                     TFVPAHPAPVVTQVLAQLDALGVGFGACHTEFVVHEGRARIIEVNYRAIGDQCDLLLAH
                     LLEIPLFEHILRTHLGEPLPADLGARRDGVARLDYPCAESAGTLTAAPAAAERTVDGVR
                     LTYRPLREIGERHQVYRTNRDFLGVVRATGTDQEAVDRAVAGFLAGQRWEIQP"
     misc_feature    19391..19404
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.61"
                     /tool="antismash"
     misc_feature    complement(19404..19424)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.91"
                     /tool="antismash"
     misc_feature    19421..19435
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.18"
                     /tool="antismash"
     misc_feature    complement(19515..19533)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 24.99"
                     /tool="antismash"
     gene            19568..20422
                     /locus_tag="IGS71_RS37365"
                     /old_locus_tag="GCM10017557_76230"
     CDS             19568..20422
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006373671.1"
                     /locus_tag="IGS71_RS37365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_76230"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_190854339.1"
                     /transl_table=11
                     /translation="MTVALETPSTDVAATVPGLLSDTYRQLAETCQALTVRVADPVPRF
                     PRTGVSGAELTKDQGAREAFLSAEDYRIRERYDHVPRHDVAASRALHDYAWSVGLLMSG
                     VWYLTGRVPRIRPEDVRIDLASGAFEVSPGTDLACLPGDPAAAVPGVLALPHEEALRAE
                     LRVAVADHMEPLLSAIAPYVRRGPRALWGLVTDDLVSGIWYLGRMLGREPDAVRAATAL
                     LPSAVPPFPGGADFRHLTGGDGRQHPTRTRMGCCLYYTIRPAEACATCPRTCDAERLRR
                     IES"
     gene            complement(20534..22591)
                     /locus_tag="IGS71_RS37370"
                     /old_locus_tag="GCM10017557_76240"
     CDS             complement(20534..22591)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982676.1"
                     /locus_tag="IGS71_RS37370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_76240"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_190854341.1"
                     /transl_table=11
                     /translation="MRGSPTDPSSSTRHSTRHRSARRAAGAVASAALLLPLLGAAPYDG
                     DGDGRGDRDGPTSASFAFSASSASSAHLQNAFADAADKYDVPQSVLLAVSYLQSRWDTH
                     DGAPSVTGGYGPMHLTDARTAIARTVVAPHHSDGREDARGDASRGPLLPDTKVPENTRL
                     PARLKTLTKAAELSGIPAERLRTDAAANVAGGAALLAAAQKQLGEPLSADAADWYGAVA
                     RYSGADDTATAATYAEEVFEVIRHGERRTTDAGQRITLGAQPRLRPATAQLSGAGLRAP
                     AAGTTECPTTVSCEWIPAPYEEFGDGDYGNHDLGDRPKSQSIKYIVVHDTEGAWDGVLN
                     LVQDPTYVSWQYSLRSTDGHIAQHVKAKDVAWHAGNWYINSKSIGLEHEGFLTAPDTWY
                     TEAMYRSSARLVKYLAAKYGIPLDRQHILGHDTVPGTTTATIPSMHTDPGPYWDWRHYF
                     TLLGKPLGAAPGAKGGLVTVLPRFTANRPEFTGCVTRGEPCAAHGSSAVRLHTQPRKDA
                     PLVKDIGLRPGGDDSTTDVNDVGSRVSTGQRYAVAGRDGDWTAIWYLGQKAWFENPQKQ
                     PTAVNATGDVITPKAGLTEIPVYGRAYPEKEAYPQGVPVQSVSPLPYKLPAGQKYAAGD
                     KVPGEYFYAPTFDTTPHLVVRGSDMYYEIQFGHRVAFVRAADVRVMPSAA"
     misc_feature    22856..22875
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 25.31"
                     /tool="antismash"
     gene            complement(22893..24035)
                     /locus_tag="IGS71_RS37375"
                     /old_locus_tag="GCM10017557_76250"
     CDS             complement(22893..24035)
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474392.1"
                     /locus_tag="IGS71_RS37375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_76250"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_055517264.1"
                     /sec_met_domain="APH (E-value: 3.4e-17, bitscore: 62.0,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTASSSVSAPPRSLHARPGGGGPYLDPARPAAAPALGAGRTRRV
                     PGLGTQPLSGRLDLSGAQGAQLRTAITSVHRICPEFAPVQVLRRSGRSVLLVGTTGRST
                     AVAKCLLDHSPVWAERIRHEIAAYRSFVRHRPPVRVPRLIAADPDNCTLVIERMPGRVA
                     ALNRHPLEAPPRADIRAALGAICRLNAWRPPAGTFDAPLDYAARISRYHELGLLTDRDL
                     GDLQKLVHGIAHSAGRQGMGQFCHGDSLLSNMLLSPAGPVLVDWEHAGWYLPGYDLATL
                     WAVLGDAPAARRQISQLAQSAGPAARDAFLVNLMLVLTREIRTYETAVQRSMHDPTPVA
                     PGPAHPGAAPSGEEQRLLLRRLHDDCQMARKAVRAAVGTR"
     misc_feature    complement(23706..23708)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(24067..24079)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     gene            24268..25767
                     /locus_tag="IGS71_RS37380"
                     /old_locus_tag="GCM10017557_76260"
     CDS             24268..25767
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020118050.1"
                     /locus_tag="IGS71_RS37380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_76260"
                     /product="hypothetical protein"
                     /protein_id="WP_190854343.1"
                     /transl_table=11
                     /translation="MSGQPNTRLSDLFGLAGWSKGELARMVNRQAAAMGHPQLATDTSR
                     VRRWIDMGEIPRDPVPRVLAALFTERLGRVVTMEDLGLVRHGRTGKRQSGGSAEHPDGV
                     PWAPERTAAVLTEFTGMDLMLNRRGLVGAGAALAAGSAISSSMHEWLHTDPALAADAPE
                     TDHPLHADPAGFDRYEAAPIGSQEIEELERSVEVFRAWDAARGGGLQRKAVVGQLNEVG
                     GMLSYRHPDHLQRRLWGVAANLAVLAGWMSHDVGLEPTAQKYFIIAAHAAREGGDRPRA
                     GEALSRAARQMVHLGRPDDALDLMKLAKSGSGDEVLPRTQAMLHTIEAWAQASMGKGQA
                     MRRTLGEAEDLFVSDSGDVPPPSWMQLFDEADMHGMQALAYRTLAEHEPAAAAVAQRHA
                     KEALALREKGRNRSQIFDHISLASACFIADDPEQADRYARLALTSMGSNSSHRTWDRLR
                     EMYRLTGQYSSYPKIHDLREEIKLSMPKGSLKQRGTNNARA"
     misc_feature    24310..24325
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.26"
                     /tool="antismash"
     gene            complement(25812..27332)
                     /locus_tag="IGS71_RS37385"
                     /old_locus_tag="GCM10017557_76270"
     CDS             complement(25812..27332)
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474388.1"
                     /locus_tag="IGS71_RS37385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_76270"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_190854344.1"
                     /transl_table=11
                     /translation="MPSHLSADHPAAQPPPRGSVDALISQTRRLRGDMDAVRRDAPTDG
                     TDPEGRWQRALCDLAMHQLNDLDAHLAQLRDGPRPVPVEPEAAPPAVRAVPAASSPHGS
                     LISRVGSAEWNLLTDEASWSGELYRIVGRDPAAPPLTLDELPSVVLDEDRPRLTSMVTD
                     CLIDAKPIDGEFRMLRPDGDVRTVHMMGEPVLDVDGSTVSMWAVLRDVSELRRSQRTVS
                     ETRDSLQRQRHVAQTEHRLAVELQEAVLPPWRGSLRPEQGPGTLELAARYLPSSTSALI
                     GGDWYDAFELPGGDTLLSAGDLTGHGVTVTSGVAMLLGALRGMAVAGTEPGRLMTWLNQ
                     LFDASARPTLGSAVCCRYRPQSRTLVWAQAGHPAPLLFRNGTGRTLTPPAGVLLGATSG
                     AVYGQAEEPLEPGDLLLLHTDGLAPLREGSPRPAAAHTGRPDLIGTDDTGGTVETGEGA
                     AAVSRLLGLAPRFGEARTAQDCVRTVVEEFGETERADDACVLVARVTT"
     gene            complement(27610..28350)
                     /locus_tag="IGS71_RS37390"
                     /old_locus_tag="GCM10017557_76280"
     CDS             complement(27610..28350)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563866.1"
                     /locus_tag="IGS71_RS37390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_76280"
                     /product="HAD family hydrolase"
                     /protein_id="WP_190854346.1"
                     /sec_met_domain="HAD_2 (E-value: 2e-11, bitscore: 43.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRSPLPVCGPEGPLRATTPERVPAPVRAVLFDFGGTLFQVGTYA
                     DRIRTVLRQPVGEREMDRLLDGLETGLTDPQVVEAQRGRDVSSRAHRHAFTTWYASVPE
                     LAPHADALYAQLRAPEHWVPYADTGSTLARLTGGGIALGVVSDVGWDLRATFAHHGLDQ
                     HISSWVHSYAHDTEKPDPVLFGHACRELGVSPAETLMVGDHPAKDGGAAGAGLRAYVLP
                     AGAAPGAHRGLDAVLRLAGVSSGA"
     misc_feature    complement(28349..28365)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.86"
                     /tool="antismash"
     gene            complement(28453..30138)
                     /locus_tag="IGS71_RS37395"
                     /old_locus_tag="GCM10017557_76290"
     CDS             complement(28453..30138)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (101-306). E-value:
                     4.1e-20. Score: 64.4. Matches aSDomain:
                     nrpspksdomains_IGS71_RS37395_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019526797.1"
                     /locus_tag="IGS71_RS37395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_76290"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_246596651.1"
                     /sec_met_domain="PF00561 (E-value: 1.1e-26, bitscore: 92.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLPTQRRRAFTCAMTMALLGAGLPSVAAAAADRSDLSHFYDQRIK
                     WSACAGDGLPEGLQCGKVTVPLDYANPADGTLDLAMARFRATGKSRGSVLLNFGGPGGP
                     GVSELSDGGKDFMGLTNGYDVVTFDPRGVGRSSPVSCGDSTDEAMGSTDVDPDDPDDGA
                     EAESEADESADVRAALDVLRKVAKDCADHSGPVLEHIGTVDASRDLDVMRAAVGDKKLN
                     YLGFSYGTRLGAVYAAKFPKKTGRMVLDGVDTLTEPLSEQGIIGAQGQQTALEDFLDWC
                     TEDVNCAFGQDPRSAREEVVRLIHSLDEDPVPSDFGIPFSGQDLVGAMGQALYSKELWP
                     TLSRALTSLVQDGDTRGIMGFHSGGSKVPGTGGHARNEDRNGNGNGNANGNGNRDEGGG
                     GSGDWDGGLVDEGDIPLDNLPAALMAINCADDPDRPTAHQITENLRKLRAKYEQASPVF
                     GRYRLAEALMCYGRPKGTSYIRDEVRDVDTSEMLLVGTRGDPATPYRWTTETADRLGPS
                     AVVLDNKGEGHTGYASSKCVHRKVDDFLLYGRLPADGSSCGSEE"
     aSDomain        complement(29221..29835)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IGS71_RS37395_Abhydrolase_1.1"
                     /evalue="4.10E-20"
                     /label="IGS71_RS37395_Abhydrolase_1.1"
                     /locus_tag="IGS71_RS37395"
                     /protein_end="306"
                     /protein_start="101"
                     /score="64.4"
                     /tool="antismash"
                     /translation="GGPGVSELSDGGKDFMGLTNGYDVVTFDPRGVGRSSPVSCGDSTD
                     EAMGSTDVDPDDPDDGAEAESEADESADVRAALDVLRKVAKDCADHSGPVLEHIGTVDA
                     SRDLDVMRAAVGDKKLNYLGFSYGTRLGAVYAAKFPKKTGRMVLDGVDTLTEPLSEQGI
                     IGAQGQQTALEDFLDWCTEDVNCAFGQDPRSAREEVVRLIHS"
     misc_feature    complement(30302..30319)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 23.88"
                     /tool="antismash"
     gene            30413..31144
                     /locus_tag="IGS71_RS37400"
                     /old_locus_tag="GCM10017557_76300"
     CDS             30413..31144
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662903.1"
                     /locus_tag="IGS71_RS37400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_76300"
                     /product="chaplin"
                     /protein_id="WP_190854347.1"
                     /transl_table=11
                     /translation="MKRVARNGLIIAAAASGAVAVTMPAYADSAADGASAHSPGVISGN
                     TLHLPVHVPVNACGNTVNVVGLLDPAAGNSCADEGDGRGGGKGHGKGSGTAGGHKGSAG
                     TVAEGGAKGSPGLISGNGVALPVDLPVNVTGNSVNVVGIGNPAVGNESTNTSGDRPHHP
                     ATPSKPPVKPADAADPVEPEAAPRILPQGATEATLARTGTDLMGPTVAAGAALMLGGAA
                     LYRRFRPTAAVQRSERRAAGR"
ORIGIN
        1 gttccactcc ggtgacctcg cggtgcggga cgtccacggg tacttcaccg tcgtcgaccg
       61 ggtgaaggac gtcatcaact ccggaggcgt actggtcgcc tcccggcagg tcgaggacgc
      121 gctctacacc catccccagg tggccgaggt cgcggtgatc gggctgccgg acgagcggtg
      181 gatcgaggcg gtcaccgcgg tggtcgtccc ccgcggcgag gccggcgggg tcggcgagac
      241 cggcggggtc acggaggccg aactgatcgc ccacgcacgc gagaagctcg cccacttcaa
      301 ggcaccgaag cgggtgctct tcgtggcgga gctgccgcgc aacgcgagcg ggaagatcct
      361 caagcgggaa ctgagggacc ggttcgggga gggttcccgc gcggccgggc ccggtgactg
      421 aataccagct ggccgaatcc cgatcggccg aatcctcaca gggttgaact caagccgccg
      481 gtgagccgta ccagtaacgg cggcccgacc acccgagcct ggtctccgcc gagtcaccac
      541 cgggtttcgc acggaaggac cttcgggttg tctagcacca cgaactctca ccagttgccg
      601 gacacggacc gggcaacccc ggaggaaccc gcgacgccgg aggcactgcc tccggcggac
      661 agcacaccca ccgagaaacc gggcacgccc gccgggacga cggacgccgc caccgcggaa
      721 ccggatgcgt cggctgatgg cggagccacg tcggccgagt ccgaggccga gggcgagcac
      781 gaggttgagg ccgaggacga gaacgtcccc accgacgacc tcaaaggttc ccccaactcc
      841 ccggacacgg gcctgcccga cgacaaggac ccgtccgccg acgacggggc cgtgggcgac
      901 gagcccccgg ctcccaaagg ctggcgcgcc aagtaccccg tcgcggcccg gaccgtgacc
      961 tggacgatca ccgtcctcgc cgccctgctc gtgctgttcg cgctcctcat gccgaacgag
     1021 atcgatcgct tccggcccgg agtgttcttc cgcctgccgg tggaggcgat cttcggcgcg
     1081 gccgtcctca tggtcctgcc gaaaacactg cggctggtgg cggcggtcct cgccggtctg
     1141 ggactgggcg cgctgaccgt cctcaacctt ctcgacctcg gcttcaacga attcctcggc
     1201 cgcggcttca acgtcgtact cgactggatc ctgttcgacg acgcccggac gtaccttgag
     1261 gactcgatgg gcaaggccgg cgcggtcggt gtcgtgatcg cggtcatcgc gctcgtcgtc
     1321 gccgtgttcg cgctgatggt cctgtccgtc gtccggctcg ccaacctgct ggcccggcac
     1381 agcggtcgcg cgacccgtgc cacgctgatc gccggcaccg tctgggtcgc ctgttccgcg
     1441 ctcggcgtgc agttcaccgg ggtgcagttc gcgtcccgca gcgccgcagg cgccgtccag
     1501 aatcgggtgg accgggtgca ggcgaccctc aaggacgagg cggagttcgc caaggtggcc
     1561 aagaaggaca ccttcgccaa cacgccggcc gaccagctcc tcaccgatct gcggggcaag
     1621 gacgtcatct tcggcttcat cgagagctac ggccgcagcg ccatcgagga cccggtcatg
     1681 gcgcccggtg tcgatgccac gctcaccgac aagaccgagg agctgagcaa ggccggatac
     1741 tcggccaaga gcggctggct cacctcggcg acgtacggcg gcagcagctg gctcggccac
     1801 tccaccttcc tgtccgggct gtggatcagc aaccaggccc gctaccgcac cgtcaccgcc
     1861 ggcgagcacc tgacgctcac cggcgccttc cagcgcaccg gcgcctggcg gaccgtcggc
     1921 atcatgccgg gcgtccagaa gaactggccc gaggcctcgt tctacggcct cgacaacgtc
     1981 tacgactcac gggaactcgg ctacgagggc cccaagttca gctggtcgac catgcccgac
     2041 cagtacgccc tgagcgccta ccagcgcctg gagcacggca agaagcgcga caagccactg
     2101 atgtcggaga tcatcctcac ctccagccac cagccctggg cgccgatccc caagaccatc
     2161 ccctgggacg aggtcggcga cggctcggtc tacaaggaca tccagaagga cggcaagaag
     2221 gcctcggacg tcttctacga ctccaccaag gtcaaggagg agtacggcaa gtccatcgag
     2281 tactcggtga ccagcctcat cgactacgtg gtgaagtacg gcaacaagaa caccgtgctg
     2341 gtcttcctgg gcgaccacca gcccctggcc agggtcagcg gcaaccacgc cagccgggac
     2401 gtgccgatct cgatcgtcgc ccacgacaag tccgtgctcg acaagatcga cgactggggc
     2461 tggaccgagg gcctcaagcc cgacgacacg gccccggtct ggcggatgga ctccttccgc
     2521 gaccgcttcc tgaccgcgta cggctcgacc ccccggccgt agaagccccc tggacccccg
     2581 gctgtgaaga ggaggccggg ggactcgggg agggccgggg aagaaggcct ctcgcgggca
     2641 taggcctacc gcgggcgcag gtccacgatg cgcctgatct tgcccaccga gcgttccagt
     2701 gactccggct cgacgatctc gacccgcgcc gagacgccga tgccgtcctt cacggccgtc
     2761 gcgatggccc gtgcggccgc gtcacggatc tccggtgtcg caccggtacg cgcctcggcc
     2821 cgtacggtga gcgcgtcgag gcggccctca cgcgtcagcc gcagctggaa gtgcggggcg
     2881 acgcccggtg tgcgcaggac gatctcctcg atctgcgtgg ggaagaggtt cacgccgcgc
     2941 acgatgacca ggtcgtcgct gcggccggtg atcttctgca tccggcggaa gacgcgtgcc
     3001 gtgccgggca ggagccgggt caggtcccgg gtccggtagc ggaccacggg catcgcctcc
     3061 ttggtgaggg aggtgaacac cagctcgccc tccgcaccgt ccggcagcac ctcgcccgtg
     3121 agcggatcga cgacttccgg atagaaatgg tcctcccaga tgtgcagtcc gtccttcgtc
     3181 tccacgcact cctgggccac tccggggccg atcacctccg acagtccgta tatgtcgacc
     3241 gcgtcgatgg cgaaccgctc ctcgatctcc cggcgcatct cctcggtcca gggctcggcg
     3301 ccgaagatgc ccacgcggag cgaggtgtgg cgcgggtcca cgccctgccg ctcgaactcg
     3361 tcgaggatcg tcagcatgta cgagggcgtc accatgatga tgccgggccg caggtcctgg
     3421 atcagctgga cctggcgagc ggtcatgccg cccgacgcgg ggatgaccgt acagccgagc
     3481 cgctcggcgc cgtagtgtgc gccgagccca ccggtgaaca gtccatagcc gtatgccaca
     3541 tgggccgtgt caccaggccg gccgcccgcc gcgcggatcg agcgggccac catgtcggac
     3601 cacatggaca ggtcgttctc ggtgtatccg acgaccgtgg ggagtcccgt ggtgccgctg
     3661 gaggcatgga tgcggcggat acggtcccgg ggcgcggcga acatcccgta cgggtagttg
     3721 tcgcgcaggt ccgccttcgt ggtgaagggg aagcgtgcca gatcggcgag cgagccgcag
     3781 tcctcgggcc gtagcccggc cttgtcgaag gagtcgcgat agaacggcac gttctcgtag
     3841 gcgtgccgca gggtggcccg gagccgctcc agctggagtg cgcgcagacc gtccgcgtcg
     3901 agccgttcgc ccgcgtccaa caggtccgtc gagttcgcca caggcactgc tcccctcacc
     3961 catgcgccat ttcggacgac cgatcattcg gttgtgccgt cggagatcaa gtaatccagc
     4021 cgcgagggcg gccgtcaagg agtgcggtgg gaaccggcgg ctcccgttca ccctcttcgc
     4081 taccgaaggg tgatcgaggt tcgagagatg ggagggggcc gctgatgtca cgcactggga
     4141 agagggctgc cggggtgggc ggactggtcg ccgtactggc ggcggcctgt ctcggctggg
     4201 cggtctgggc ggtggcttct tccgagcgcc atgtcggcga ggacgcgcgg gccggagacg
     4261 cgcggagccg agcggtgcag gttccgtgcc gggaggcgtt acggttcgcg gaccaggagc
     4321 ggctgccggc cggggccaag gacgccgcct gtgtgatgca gcacggcatc gacacgctgt
     4381 acgacgtcgg gttccgcatc agcaggaccg gcctcgacgc atggctggcg gacacctacc
     4441 ccgacatgaa gctggactcc acgtgcgtcg aggacgacgc cgaccgctgc gggcacctgg
     4501 acctccaccc gtacgccgaa ggaggcgccg tggccctgga gttgacggtg cgggacgaga
     4561 gcgacggctc cgccctcgtg cacttcaaac ccttcaacac gtgaaccgac gacgtgcgcg
     4621 tgacgctgcg ccggcgtgcc cccgactcct actcctactc tggcgccgcc cctgcctccg
     4681 cctccgcctc tgcttccgcc gccaccgacc gtgcccaccg gtagtccgcc ttgccgctcg
     4741 gggaccgctg gatggcttcc gtgatcacca gccggcgcgg gatcttgtag cccgccagat
     4801 gcgtacgaca gtgggtctgg atgtcgtgca gggagggtcg gccgccgcct tcgcgcagct
     4861 gcaccacggc cgccacatgg gtgccccatg tctcgtcggg caccccggcc accagcgcgt
     4921 cgtacacgtc cgggtgtgac ttgagggcct gctcgacctc ctccggatac accttctccc
     4981 caccggtgtt gatgcactgc gaaccgcggc ccaggacggt gacgacgccc tcctcgtcga
     5041 cggtcgccat gtcgccgagc agcacccacc gctcgccgtc cttctggaag aaggtctcgg
     5101 cggttttccg cgggtcgttg tagtagccga gaggcacgtg tccacgctgg gcgatgcggc
     5161 cgggctcgcc cacggcgacc ggctcgtgcg tcgccgggtc caccacccgc gtgcgggagt
     5221 tgacctcgat gcggaagccg cggtccgggc ccgagtcggc cgtcgccgtg ccgttgaatc
     5281 cggactccga ggacccgaag ttgttgagca gcagcacgtt cggcacgagg gcctggaact
     5341 gggcgcgcac cgtctccgac atgatcgcgc cggacgagga gacgctgaac agggaggagc
     5401 agtcggtgcc cttcatgggc ccgttcagcg cgtcgatcag cgggcgcagc atcgcgtccc
     5461 cgaccagcga cacactggtc accttctcct tctcgatggt acgcagcact tgttcgggca
     5521 cgaacttgcg gtggatcacg acgcgttggc cgaagtggaa gccgatgaag gcggtgaggg
     5581 tcgaggtgcc gtgcatcagc gggggcgtgg ggaagaaggt gatcccgtcg ccgccggccg
     5641 cgacccgctc ggcgagctcc tccggcgact tcaccggctc tccggtcggg gcgccaccgc
     5701 ccaaccccgc gaagaacaag tcctcctgac gccacatcac gcctttcggc atcccggtcg
     5761 tgccgccggt gtagatgatg aactggtcgt cggccgagcg tgccgggaag ccccgcccgg
     5821 gggctccggc ggcttcggcg tccgcgaagt ccaccgcagg caaggcggga gcgtccggtg
     5881 ccgggacccc cacccgtacg agatgccgca gcgccgaggc gcgcggcagg gccgccgcga
     5941 cccgtccggt gaactccgcg tcgaagacca gcgccaccag gtccgcgtcc cggtagatgt
     6001 aaatcaactc ctcctccaca taccggtagt tgacgttcac cggcacgatc cgcgccttca
     6061 ggcaccccag gacggtctgc aggtattcga tgccgttgta gaggtgcagc ccgagatgct
     6121 caccgggacg gatgccgccg gcgagcaggt ggtgggcgac acggttggcc gccgcgtcca
     6181 gctccgcgta tgtcaggcgc cgctcggctc ccgtaccggg atggtcgatg tggacgagcg
     6241 cctcgcggtc ggggaccacg tcgacgaccg actcgaacag gtcggcaagg ttgtactcca
     6301 ccgctcctcc tgaccccggc aagcatcgac gagtggacgt gcgtcatcgc ttcgccggtc
     6361 atcagagcaa agcgaggcac aactgggaag ggtccgcaca gaagtaatct gactggctgt
     6421 cagaaaaccc ttgaactgct tccgcgcctc ctgcaacctg ttctcgttcc tgagacggga
     6481 ggacggcaat gggtgggacg gaacacctca ccgtgcagcg cgaaggcgcc acactggtgc
     6541 tcacgctcaa caggcccgag gccaagaacg cgctctcgct gccgatgctg gtcggcctct
     6601 acgacggctg ggtggaggcc gacgaggacg acgccatccg ctcgatcgtc ctgaccggcg
     6661 cgggcggcgc gttctgcgcg ggcatggacc tcaaggccct cgcgggcaag gggatggagg
     6721 ggcaggagca ccgggaccgc ctcacggccg accccgatct gcactggaag gcgatgctgc
     6781 gccatcaccg gccgcgcaaa cccgtgatcg ccgccgtcga gggccactgc gtggccggcg
     6841 gtaccgagat ccttcagggg accgacatcc gggtcgcggg ggagtccgcc accttcgggc
     6901 tcttcgaggt gaagcgcggg ctctttccga tcggtggctc gacggtgcgt cttcagcggc
     6961 agattccgcg cacgcatgcg ctggagatgc tgctcaccgg ccgtccgtac tcggcgcggg
     7021 aggccgccga cgtcggtctg atcggtcacg tcgtcccgga cgggaccgct ttggagaagg
     7081 cactcgccat cgccgcgcag atcaacgcct gcgggccgct tgccgtcgag gcagtcaagg
     7141 cgtccgtgta cgagaccgcc gacatggccg agtccgacgg gctcgccgcc gagctgaagc
     7201 gggggtggcc cgtgttcgac acggccgatg ccaaggaggg ggcgcgggcc ttcagtgagc
     7261 ggcgcgcggc ggtgtatcgg cgggagtgag ctccgctcgc cggtcggttc acagccgcgg
     7321 gttcgttgtg gctggtcgcg cagttccccg cgcccctttc aggggcgcgg ccccgccatt
     7381 ccgtgaggag atgctgtgac tgaagttctc aaagctccgt tggtcgtcga gtttcccttc
     7441 acccggtctc tcgggcccgt gcagagcgcg tttctcaccg ggctgcgtga gcgggtcgtg
     7501 ctcggggtgc ggaccgggga cggccgcgtt ctcgtgccgc ccgtcgagta cgaccccgtc
     7561 acctccgagg agatcggcga gctcgtcgaa gtcgcgacca ccggcaccgt caccacctgg
     7621 gcctggaacc acgaaccccg ccgggggcag cccctcgaca cgccgttcgc ctgggtcctg
     7681 gtgcggctgg acggtgccga caccgccctc ctgcacgccc tcgacgcccc cggcggaccc
     7741 gactccgtac gcaccggcac acgggtacgt gtccgctggg ccgaggaacg ctccggcgcc
     7801 atcacggaca tcgcctgctt cgaaccgtac gaatcgccca acccgcacga actgcgcgat
     7861 ccgtacatcg gcggcgccgc cgcactcgtc ggcagcgacg gtcggttcga ggatccggtg
     7921 acgggcatcg tcgcgcccgc ccgtctcgac tacacctact cgccagggcg cgcccagtcc
     7981 gcctacatcc ggtcgctcgc cgaccggcgg gtcgtcgggg agcgctgccc gtcgtgccgc
     8041 aaggtgtacg tcccgccgag gggtgcctgc cccacatgtg gtgtggccac atcggaacag
     8101 gtcgaggtgg gtccgcgcgg gaccgtcacg acctactgca tcgtcaacat caaggccacc
     8161 cacacggcga acctcgacat cgaagtgccg tacgtctacg cgcacatcgc cctcgacggc
     8221 gccgacctcg ccctgcacgg ccggatcggc ggcatcccct acgaccaggt gcgcatgggc
     8281 ctgcgggtcg agccggtgtg gtcggaggcg ggcggccatc ccgaccacta ccggcccacc
     8341 ggtgaacccg acgcggacta cgagacgtac aaggagctgt tgtagatgcc cgcaccgagg
     8401 ccgctcaggg acatcgcagt cgtcgccttc gcgcagaccg accaccggcg caccagcgac
     8461 gatctctccg aggtcgagat gctcatgccg gtcctgcacc gggtcctggc gcagaccggg
     8521 ctgaagacca gcgacatcgg attcacctgc tccggctcca ccgactatct cgccggccgg
     8581 gccttctcct tcaccatggc actcgacggc gtgggtgcct ggccgccgat ctccgagtcg
     8641 cacgtcgaga tggacggcgc gtgggcgctg tacgaggcct ggacgaagct cctcaccggc
     8701 gacgcggaca ccgcgctcgt gtacgcgtac ggcaagtcgt cccccggctc cgtacgcgac
     8761 gtactgaccc ggcagctcga cccgtactac gtcgcgcccc tgtggcccga ctccatcgcc
     8821 ctggccgccc tccaggcgca ggcgctcatc gacgcgggcg atacggacga gccggcgctc
     8881 gccgccgtcg cctcccgcag ccgcgcctcc gccaccgaca acccccatgc ccagttgcgc
     8941 ggttcggtgc cgcggggcga ctacgccgta cgccccctgc gtaccgggga ctgtccgccc
     9001 atcggggacg gggcggctgc cgtgatcctc gccgcggggg accgggcccg tgacctgtgc
     9061 gagcggcccg cctggatacg aggcatcgac caccgcatcg aggcgcacgg gctgggcgta
     9121 cgggacctga ccgactcacc gtcgacacgc ctggcggcgg agcgggccgg tgccttcgaa
     9181 cggcccctgg acacagccga gttgcacgct cccttcagct cccaggaagt ggtactgcgc
     9241 aaggccctgc gactggacga cggcgtcgac gtcaacccgt cggggggagc gctcgccgcc
     9301 aaccccgtca tggccgcggg cctcatccgc ttcggcgagg cggctgcccg gatcggccgc
     9361 ggtgcctccg acagggcgtt ggcgcacgcc acttcgggcc cctgcctgca gcagaacctg
     9421 gtcgccgttc tggaaggaga cccgcgatga gcgacaccga gagcaatgcg ctgagcaatg
     9481 cgctgagcaa tgcgtcgggt aatgcgctga gtagtgcgac gggcaaggag cccgtggcgg
     9541 tcgtcgggat cggtcagacc aagcacgtcg cggcccgaag ggacgtgtcg atcgcgggac
     9601 tcgtccggga agcggcccga cgcgccctcg ccgacgccga gttgacgtgg gcggacatcg
     9661 acgccgtcgt catcggcaag gcccccgact tcttcgaggg cgtcatgatg cccgagctct
     9721 acctcgccga cgccctgggc gccgtcggca aaccgatgct gcgcgtccac accgcgggct
     9781 ccgtcggcgg ctccaccgcg ctcgtcgcca cgaacctggt cgcgggccgc gtccacggca
     9841 ccgtactgac cctcgcctac gagaagcagt ccgagtccaa cgccatgtgg ggcctgtccc
     9901 tccccatccc cttccagcag cccctgctcg ccggcgcggg cggcttcttc gccccgcacg
     9961 tgcgtgccta catgcgacgc accggcgctc ccgacacggt cggctccctg gtcgcgtaca
    10021 aggaccgccg caacgcgctc aagaacccgt acgcgcatct gcacgaacac gggatcacgc
    10081 tggagaaggt ccaggcgtcg cccatgctct gggacccgat ccgctactcg gagacctgcc
    10141 cgtcctccga cggcgcctgc gcgatggtcc tcaccgaccg cgcgggggcg gcccgttcgc
    10201 cgcggccacc cgcctggctg cacggcggcg cgatgcgcag cgagccgact ctcttcgccg
    10261 gcaaggactt cgtctccccg cgcgccggca aggactgcgc ggccgacgtg taccggcagg
    10321 cgggcatcgc ggacccccgc cgcgacatcg acgcggtcga gatgtacgtc ccgttctcct
    10381 ggtacgagcc catgtggctg gagaacctcg gcttcgccga cgagggcgag ggctggaaac
    10441 tcaccgagtc cggggtcacg gaactggacg gtgacctgcc ggtgaacatg tcgggcgggg
    10501 tgctgtccac caaccccatc ggggcctccg ggatgatccg gttcgccgaa gccgcacttc
    10561 aggtgcgtgg acaggccgga gaacaccagg tcgacggcgc ccgccgggtg ctcgggcacg
    10621 cctacggcgg cggttcgcag ttcttctcga tgtggctggt cggagccgcg ccgcccacct
    10681 cctgaactgt ccccctcgcg tggcctgtgc ggggcaggga ccgaaagcta ggctggccgc
    10741 gcacgacgca accgggagga gcacgacgtg gccgagagca ccatccagca gcacccgctc
    10801 gcgggctggg acaagccgga gcttgacctc agcagcgccg actggcattc gagcagccgg
    10861 gggctggggg atgtccagat cgcctttgtc gagggattca tcgcgatgcg caacagtggc
    10921 cgcccggaag gcccctcctt gatcttcaca cccgcggagt ggggcgcgtt cgtgtcgggg
    10981 gcacgggagg gggagttcga cctcacctga tgagggtttc cggttccttt ttccggacac
    11041 gcgatcttcg acctcttcct ggggactgcc tgagcgaggc tgaccccagg aagcggatga
    11101 agacgttccg gaggcgagaa cttcatgaac accctgccgg tcatcgctgc ggtcgacgga
    11161 tcggacgaca gcctgcgcgc cctcgactgg gctctcgacg cggcccgtgg gcgcgaggca
    11221 cccctgcgcg tggtccacgt gcgggaaccg gggccctggc tgcggcccga gacactcacc
    11281 gccggccggc cggagccgga caccgacccg gtcctcgacc tggtccgcga ccggctcaag
    11341 gacctggcgc gcgacgcgcc ggtcacggag tacgtcacga cggagtacgt cacgctggac
    11401 ggcgcccccg ccgccctgct gcccggcctc ggctccgaag cgcagctgct ggtctttggc
    11461 tcccgtggcc gtggggggtt cgcgagcctg ctcctcggtt cgaacgggac ggccgccgcg
    11521 cgcgacgcgg agtgtcccgt cgtggtggtc cccaggcccg gacgcgaggt ccacgactcc
    11581 gagctcgtca cccccggacc gcgtgtggtc gtcggcctgc acgtggacag cccgaacaac
    11641 gaggcacttg ccttcgcgtt cgccgaggcc gcccggcgcg aggcccgcgt ccaggtggcc
    11701 gccgtgttcc cctggctggt gcaggccggg gacctcgtgc caccgccggt cgtcgacgag
    11761 gacgccatcg agtccgagac aaggaccctg gccacgggct tcgtcgctcc gcacgccgag
    11821 cggcaccccg gggtcggcac cgacctccac gtgctgccgg gcgacgcggc gggccaactc
    11881 gtcgcggctt cccgaggcgc cgatctcgtg gtggtgggcc gccaccgcag gcgcctgctc
    11941 gcgcccgccc gcatgatcgg ctcggtcacg caggcggtgc tgctgcacgc ggcgagcccg
    12001 gtggcggtgg ttccgccgga cgggacggag gggtgagggc cgaggaccga ggaccgagga
    12061 ccgaggaccg acggccgatg gctgaatact gagaaagcgg cacagcctcc ggccgtgagc
    12121 ggcgcgagcg gcctgggcga cgcgtgggcg gcgtgcggga ggcgcgggag cggtgtgagc
    12181 agggaggccg gcagccgtcg gccccgcgcc ggttcgcccc ccggtgcacg taccattgcg
    12241 gcatgtcctt cctccgccgc cgcagcgcca ctcccgccgg gccagacttc gacgttctgg
    12301 ccatggatcc gggcgactgg ccgggcaacc tcggcgcggg cctgctgccc gcacccgatg
    12361 gcagctgtca gggtgtgttc ctgcgctacg acctgttcgg cggccgcggc cccgcgatga
    12421 tcatcggcaa tctgccggag ggctccccgg cccgggacgt ccccgaggga gaggttccgt
    12481 tcgaggtggc ccagctgctg ctggcgctgg agaacgacga agaggtcacc gtcgccggcg
    12541 ccgaggacat gccggtgatg cagggcgaca acctcctcat cgtgcgccgc ctcaagctct
    12601 ccgagacgcg catctcctgt gtgcagttcg accgcagtga caaggtcctg gtgacgatcg
    12661 ccgcctggga ccgccccatc accgacgacc tgtacgcgct gttgaagccg ctgcccgcgg
    12721 agctgttcca gcagggctga ccctgccgtc caggtggtcc aggtggtcca ggtgcttcgg
    12781 gtggtccgga tggtccggat ggtccaggaa gtggaagccg ggccgtgggt gcatgaggaa
    12841 gtcgtggtgg gagatgttcc acgcgtaggc acccgcgagc gcgaacgcca cccggtcacc
    12901 cgcccgtagc cccggcgcga ggacgtgccg ggccaggacg tccttcggag tgcacaactg
    12961 gccggtgagc gtgacccgtt cacctcgcgc caccggccgg ggccacggat gcggccagtc
    13021 ctccaccggg agcagggcgc ggggctggtc gtgccccttg gccgccgggg tgcgcaggtg
    13081 gtgcgtgccg ccgcgcacca cggcgaactc ctcgccgtgg ctgtgcttca catccaggac
    13141 ctcggtcgcg taccagccgc agtacgccgt cagcgcgcgg cccggctcga tacgcagcgt
    13201 cagatccggg tgcagggcgc agagttgggc gagcccgtcc ccgtaggcga cccagtcgaa
    13261 acgctcctcg ggagccgcgt agtcgaccgt catgccccca ccgacgttca cctcggcgag
    13321 ccgcaccccg tgccgctcgg ccagtcgcac ggcccacccc acgatggact cggcgaccgc
    13381 gagctgttcc ggagcccgaa gtccgctcgc caagtgggcg tgaacacccc ggagttcgag
    13441 gtgtggatag gtgccgtcgg tgagcagacc cacgaccgtg tccgcctggg acgggtcgag
    13501 gccgaaggga gtgggacgcc cgcccatggt gagggagctc gccgccaagg agcccgcggc
    13561 gacgggcagg ttgaagcgcg gcagcacggc gacccggccc ccctccggac cgacctgtcg
    13621 cgccaactcg gccagcatgt gcagctcgta ctcgctctcc acatggaagc gcgccacgcc
    13681 cagctccagc gcggacacga tctcggcggg agtcttgccg ggcccgccga aggccagcgg
    13741 ccggccgggc accgcctcgg cgacatgggc gagttcgccg cccgacgcga cctcgtagcc
    13801 gtccacgtac gggtcgagcg cggccaggat cgtcggctcc gggttggcct tcgccgcgta
    13861 gtagagctcg acgcgctccg gcagcgcgtc ccgcacggcc gccgcgtgtg cccgtagggc
    13921 catcaagtcg tagacataag cggggagttc atcggaggcc agggtgagta cgcgatcccg
    13981 tacggcgtcg gtggggctgg tcatcggggg ctcccggttg tgcggcggcg catgatgccc
    14041 tcgccgagtg gtgagggcag acggacgtat ccggcctcgc ggtcggcctt tcgctcccag
    14101 cgggtgagga ggttcgcctt ggcgggcagg ggcacgcccg cgagcagcgc ggccagcggc
    14161 ggcgggcagc cgtaccggtc ggcgtacgtc cggagggtgc cgcggacctc cgcccacagc
    14221 gcggcctcgg tgtgcgggtg cagatcggcg agggcggcga gcagctcggc gacgtggttc
    14281 acgagcaggc agtagacgac ccggtcccag ccgcgttgtg cgtcgtacgt cagcgggccc
    14341 gcgacgtcgg gaggcagcga ggcgagggtc tcggcgtggt gctcgggtac gagtttggtg
    14401 ccctccaggt cccggaagag gacctgggcg ggcatgccgt cgccgtcgac gcagatcagc
    14461 acgttctgca gatggggttc cagcaccaga ccgtggtcga agtaggcggc gaggacgggc
    14521 ggcacgagca gcttgagata ggccgcccac cagtcgagcg cggcccgcgg gccggctccg
    14581 tcgaggagac gggagatgtg cgcgggactg gtggggtact cgtccgccac cgccgccgcg
    14641 agcagcgggg tggtgccggg cagcagacgc ctggccaggc cctcgcggac gatgacgccg
    14701 aagccttcga gcaggtcgcg atccggggtt ccgtcggggc cgggcagggc gagactgcgg
    14761 tacgcgggct cgcggagcac cgcgctgccg gggaaccggt cggccaggcc ggcgagcacc
    14821 gggcccagca cacgggtgag cgcgacggcg cctgacagct cgtaactcgc gttcttgcgc
    14881 atgcagttgg tgatccggat gttcagactg aacttaagga acgactcgcc gtcgtagagc
    14941 gtccgtacgg acgcggtggc ggcgaagggc ctgccgcccg ggccgaggtc gaggacgtcc
    15001 ccgcgtcgca gagccgcacg cagtgtcggg tgctcgccca gcatcgcgta ctgccaggga
    15061 tgcgcgggca gcagccggta gccctcgggg acggtggcgc cggcggccag ccggttccgc
    15121 ggcttccgag ggtcctgcct gcccggcgga tcgagcgggt cgagagtgct gaaggtgtcg
    15181 agcacgtcga gcgcgcccgg ctccgcggat tcctccgcga tcaggtgctc gcgtacggcg
    15241 aggtggcgca gcgggaagac cgcggcggcc tccggcgcgt aggcgagcca ggagtccgtg
    15301 tccccggtgc gcgccttggg agtggggtgg aaacggtgcc cgaacagcaa cgcctgctcg
    15361 gaggcgaggt aggcggcgac gggcgcgtcc gccgacgccg ggccggcccc cgcgtgtacg
    15421 gggacggagg cgggggcggc cccggtccgt accgacccgg aggccggagc ggtccccgtc
    15481 cgtacggaaa gggccgcggc gatggtccga tggctggagt cgatctgctc caggaactcc
    15541 tcgttgcgca cgccggtacg caggtacagc tcgtcctgcg tgagctccgc gagccgccgc
    15601 cggccgacct cactccaacc accgtccgcc gtctgctcac tcaccgggcc ggtgaagcgg
    15661 tgcgcgccga gcatcgacgt acggcgcagc gcgacacgca acagcacgcc gcggcggggg
    15721 agccgcagca acagccggcc gtcggtgacc gcggtctgct gctcgggcgc cgacacctcg
    15781 cgcaacaggc agttgagcag cgtgtgcgcc acggccaggt cggcggaggg gagttgggtt
    15841 cgtgcggtgg aagcggtgga agcggcggaa ccgggggcgg ggctgggggc gggcagggaa
    15901 gtgctaccga gtgactcggt cagcgagggc atgtgcggct ccagcaggtg caaagagagc
    15961 gaagaatggt cgcgcatgag gtgatggggg cgacggcggc gcccgaccgg agtcggggag
    16021 ggggtcggca acgccatggg ggtcggcaac gccgtgcctc gcctctcacg ccgaagtgcc
    16081 gttgagccgc aggtagttgg gcccagtggt gtagtgcttg ttgatgtccg ccgcgccgga
    16141 ccgttccttg gtgaggagcg ttccggcggt gaccatcgcc ttgaccggca ggcgtggcgc
    16201 gtccaggagc tggacccgca gtacggcacc tggctcgccc gctcctgtcc cgagccgctc
    16261 gatcgcctcg gcgagccggt cgcgtacgag ccgcagcagt acgggaagag gcgcgcgacc
    16321 gtgccgcgcg agcccgaagg cgtaggcgcc cgcgcacaga tggaccgtga tggtggtgaa
    16381 caggtccacg accggccggt cactgtcgcc gaaggtccgg gcgtcgtcga agtccccggc
    16441 gcccggagcc gcgtccccga gccgttcgct cagccgcagg cggttgatgc gcggcccgtc
    16501 gttgtccttc aacagcagcc gcagccgcgt aggaccgttg tgcggcggcc ggtcgaggac
    16561 gatcgagatg ttctgctggt gcgactcaag cgcgatcccg tacccgaaca gcgtggtctg
    16621 ccagtcgaag agcagggtca ggcaggcgtc gagcagcgcg aggaggtcac cgccgtagaa
    16681 ccggtcggcc agatgatcga cgaccagccg gccgccgggt gcttcggcga gcagcgcggc
    16741 catcggcacg acgacggagt cctggaggcc gtcggggtaa cgccggaaca gcgcggcgag
    16801 cagttcgtgt ccggcgtgcg cgtacaccgt ctcgtcggcg tgcaggatcg tgttccggaa
    16861 ccgtggctca cggacgatga tctgctcgat cagccgctgt cccgcagcgc cgtcgaccag
    16921 tgtgccgggt ttgatggttc gccggttgcg cagccccaac gtagcggtgt ccagcgggag
    16981 tttgacatgc agggacggct ccgcggtgag ggccacggta cgcatcgaca gggtcggtac
    17041 gacgtcgagg tgggcgcggt cggcgagcac ggcccggtcc gtcagaccgg tggcgcgcag
    17101 gacaccctcc agcggggcac cgacggtcaa tgggtggacg ggcagcgcca catgggtcgg
    17161 gtcgagctcc gggaggccga gcagcccggg cgtgggccag cgctccggaa acgtcccggt
    17221 gaccgcgtca cggggcacag cgagccagcg cagctcgaac gcgggatgta actccggcgc
    17281 gtacgcccgc agttgtgatt cgttcagtcc gacgcggcca cgtgcggtcg ggtagacggg
    17341 atggtcgagg tgggcggcga gggtgtcgta cgccgtccct ccgctcaatc ccgtccagcc
    17401 ggtcaccgcc gggccatgac gggctgtcag tcgccggatc acctcgtcgt gggccgcggt
    17461 gtgcaggcgc atggtggcca gtgtctgacg gcactcttcg gcgaaggcgt cgaatcctgc
    17521 ccggtcgacg ggatcggcga ggacgcgcag ggcggcgagg atcgtgtcgc acgtctcgta
    17581 gcggacgggc agaggcgtgg gtgcggggga gggtgagggg gagggcgagg gctcctcggg
    17641 ctctcttacg agcaacggca gccgggccgc gtactcgcac tggaacccgt cttcggcgac
    17701 cggaagcagc aggaactgcc cgtccccggt ggcccgtcgc agccacgcgc cgtccggcct
    17761 gtgcaccagc cggccggccg aacgcaggcc gaccacgtcc tcgcgcagca gtgcgctgag
    17821 cacccggatg accagctcac cgcgggtggt gtcggcgtcg ggagacacgc caccgtgctc
    17881 gccagtgcca gtgccggtgc cggtgccggt gccggtgccg gtgccggtgc cggtgccacc
    17941 gctccccgtg gagctgccgg ccgtcgccgt ccgggcagtc acggctggat ctcccaccgc
    18001 tgcccggcca ggaaaccggc cacggccctg tccacggcct cctggtcggt tccggtggcc
    18061 cgcaccacgc cgaggaagtc gcgattggtg cgatacacct ggtgccgctc accgatctcc
    18121 cggagcgggc ggtaggtcaa ccgaacgccg tcaacggtcc gttcggcggc ggcgggcgct
    18181 gcagtcagcg tccccgcgct ctcggcacac gggtagtcca gccgggccac gccgtcacgc
    18241 cgagctccga gatccgcggg aaggggctca cccaggtgcg tacgcaggat gtgctcgaag
    18301 agcggaatct ccagcaggtg cgccaacagc aggtcgcact ggtcgccgat ggcacggtag
    18361 ttgacctcta tgatcctcgc ccggccttcg tgaaccacga actcggtgtg gcaggcaccg
    18421 aaaccgacgc cgagcgcgtc gagctgggcc agtacctggg tgacgaccgg tgcgggatgg
    18481 gcggggacga aggtcagccg ctcctcgatg aagtacggcg gcggggacaa cacggtgtgg
    18541 aaaccgccca ggacatggcg cacgtgaccg tcgccgagcg tctccagtgt gtagagctcc
    18601 ccgggcagat actcctcgac gaccagggcg gaccccgggc ggcggctcag gatctccgcg
    18661 cagcgcgcca ccaggtcctc ggcaccctcg acgagtacga cgtcctcgct ggccacgccc
    18721 tcgcgtggct tgacgacaca cgggtacggc acgtcgaggg cagccacgtc ggtggtgtcg
    18781 gtgacctcgg ccgaccacac cgtgtccgcg cccgcggagg cgagactgcg ccgcatctcg
    18841 gccttgttct tggtgcgcag ggcgaccctc cagtccttgc cgggcaggcc gaagtagtcg
    18901 gcggccaggg cggcctgggt ctgcagatga tcgctgttgg tgaagaccgc gtcgggacgg
    18961 ccgagcgtcg agatccgggt gacgacggag cggaggtcgc gtacgtcgca ctccaggacc
    19021 tcggtctccg ggtacgcgag ccggtgggcg tccggctggt cggtgaggac cgtcatgtcg
    19081 acgccgagcc gtgccgcggc gggcagaaac ccttcggtga cggagtcggt ggggttgaga
    19141 gcaagcagga acatacgcat gcgaggagaa caactcccgc tctgtggtcg gcggttggag
    19201 gtaaacgacg gttgagggca gacggctgtc gagggcggac ggctgctgag gcagggctca
    19261 gggaggcgcc gggcgcgaag gagctccgac gccggcgagc ggcacgggta tgtgcggctg
    19321 ctggaagatg cgcgcgggca cacctgtagg cgcggcccgc gtaggtgcga cctgttcggt
    19381 cgctgtcaca tcgagtgaga tcaaattagg catgttctat ttctcaaccg gcaatggatc
    19441 tgctgtgacg tgcgcctccc ttgatcgatg tttcgggagg cgtggtcacg cactgctgtt
    19501 agcgatctct atactaaggt aaggcttacc tggttttctc gctttgcccc catgtacagg
    19561 agtaccgatg accgtggccc tggagacccc gtcgaccgat gtggccgcga ccgtgccggg
    19621 cctgctctcc gacacgtatc gacaactcgc cgagacatgc caggcgttga cggtgcgagt
    19681 ggccgacccg gtgccgaggt tcccccgaac gggcgtcagc ggcgcggagt tgacgaagga
    19741 ccaaggtgcc cgggaagcat tcctgtcggc cgaggactac cgcatccggg aacgctacga
    19801 ccacgtcccg cgccacgatg tcgccgcctc ccgcgccctt catgactacg cgtggtcggt
    19861 cggcctgttg atgagcggcg tctggtatct cacgggccgg gtgccgcgta tccgccccga
    19921 ggacgtacgg atcgacctgg cctccggcgc cttcgaggtc agccccggaa cggacctggc
    19981 ctgtctgccg ggcgacccgg ccgccgcggt ccccggcgtg ctggccctcc cccatgagga
    20041 ggcgttgcgc gcggagttgc gggtcgccgt cgccgaccat atggagccgc tgctctccgc
    20101 gatcgccccg tacgtccggc gtggcccgcg cgcactgtgg ggcctggtca ccgacgacct
    20161 cgtctccggc atctggtacc tcggccgcat gctcggccgg gaacccgacg cggtgcgggc
    20221 cgccaccgca ctgctcccct ccgcggtccc gcccttcccc ggcggcgcgg acttccgcca
    20281 cctcaccggc ggcgacggcc gacagcaccc gacccgtacc cgcatggggt gctgcctcta
    20341 ctacacgatc cgccccgccg aggcctgcgc cacctgcccg cgcacctgcg acgccgagcg
    20401 cctgcgccga atcgaatcct gacgcttttc aagggactcc cgcttctcag cgaccctgaa
    20461 ccaccccaaa cctgacaggg ctgccttgac gaaaaacata gaggcacccc ccccggcccc
    20521 tccctctgtc ccgttacgcg gcggacggca tcacccgcac atcggcggcc cgtacgaacg
    20581 ccacccggtg cccgaactgg atctcgtagt acatgtccga accacgcacc accaggtgcg
    20641 gtgtcgtgtc gaaggtcggc gcgtagaagt actcgcccgg caccttgtca ccggccgcgt
    20701 acttctggcc cgccggcagc ttgtacggca gcggtgagac cgactggacg ggcacgccct
    20761 gcggataggc ctccttctcc ggatacgcac gcccgtagac ggggatctcg gtcaacccgg
    20821 ccttgggcgt gatgacgtcg ccggtcgcgt tcaccgcggt cggctgcttc tgcgggttct
    20881 cgaaccaggc cttctggccc aggtaccaga tcgcggtcca gtcgccgtcg cgtccggcga
    20941 ccgcgtaccg ctggccggtg gagacgcgtg agcccacgtc gttcacgtcg gtcgtggagt
    21001 cgtcaccgcc gggccgcagg ccgatgtcct tgacgagcgg ggcgtccttg cgcggctggg
    21061 tgtggagacg tacggcgctc gatccgtgcg ccgcacaggg ctcgccccgg gtgacgcagc
    21121 cggtgaactc cggccggttc gcggtgaacc gcggcaacac ggtgaccagc ccgcccttcg
    21181 ctccgggcgc ggcccccagc ggcttgccga gcagagtgaa gtagtgccgc cagtcccagt
    21241 acgggcccgg gtccgtgtgc atcgacggga tggtcgcggt cgtcgtaccg ggcacggtgt
    21301 cgtggcccag gatgtgctgc cggtccagcg ggatgccgta cttggcggcg aggtacttca
    21361 ccagacgcgc cgacgaccgg tacatcgcct ccgtgtacca ggtgtcgggc gcggtgagga
    21421 atccctcgtg ctccaggccg atcgacttcg agttgatgta ccagttgccc gcgtgccagg
    21481 ccacgtcctt ggccttcacg tgctgggcga tgtgcccgtc ggtggagcgc aggctgtact
    21541 gccacgacac ataggtcggg tcctgcacca ggttgaggac accgtcccag gcgccctcgg
    21601 tgtcgtggac gacgatgtac ttgatgctct gcgacttcgg ccggtcgccc aggtcgtggt
    21661 tgccgtagtc gccgtccccg aactcctcgt acggcgccgg gatccactcg caggacacgg
    21721 tcgtcggaca ctcggtggtg cccgcggcgg gcgcccgcag tcccgcaccg ctcagctgcg
    21781 ccgtcgcagg gcgcagccgc ggctgcgcgc cgagcgtgat ccgctgcccc gcgtccgtgg
    21841 tgcgccgctc gccgtggcgg atcacctcga agacctcctc ggcgtacgtc gcggccgtcg
    21901 ccgtgtcgtc ggcacccgag tagcgggcca ccgctccgta ccagtcggcg gcgtcggcgc
    21961 tgagcggctc gccgagctgc ttctgggccg ccgccagcag cgcggcaccg cccgccacat
    22021 tcgccgccgc gtccgtacgc agccgctccg cggggatgcc gctcagttcc gcggccttcg
    22081 tcaaggtctt gaggcgggcc gggagccggg tgttctccgg gaccttcgtg tcgggaagga
    22141 gggggccgcg tgacgcgtcg ccccgggcgt cctccctgcc gtcgctgtgg tgcggtgcca
    22201 ccacggtccg ggcgatcgcc gtgcgggcgt cggtgagatg catcgggccg tagccgcccg
    22261 tgacactggg cgccccgtcg tgcgtgtccc agcgggactg cagataggac acggcgagga
    22321 gcacgctctg cggcacgtcg tacttgtcgg ccgcgtcggc gaaagcattc tgcagatgcg
    22381 cggaggacgc ggaggacgcg gagaacgcga aggacgcgga cgtcggcccg tccctgtcgc
    22441 cgcggccgtc accgtcgccg tcgtacgggg cggcgccgag caggggcagc agcagagcgg
    22501 ccgaggcgac ggcacccgcg gcccggcggg cacttctgtg gcgggtggaa tgccgggtgg
    22561 aagagctggg gtcggtgggg gatcctcgca aggcagacct cctgggacga tcgagtgtga
    22621 cggtgcgtgc gtacgggggc gggtgtgcgt cagtgctacc ggctctccga caatccgtca
    22681 atcattccca gaggaagcgg atttcccacg tcagcggcgg gggttcaccg tattcggggc
    22741 ggcgatgacc cggcctgcgc ggcaacaggg gaagtgacct ctgacccgat cgggtgaaac
    22801 ccttcaccac cgggtgaacg acggaggtcc gcgacacgcc cctgtcctgg gcgcatcgcg
    22861 gaccaccgtc cctgtcagcg ctatcagcgc cgtcagcgcg taccgaccgc cgcgcgaacg
    22921 gccttgcggg ccatctgaca gtcgtcgtgc agccgcctca gcagcagccg ctgttcctcg
    22981 ccggacggcg cggcacccgg atgggccgga cccggcgcca ccggggtcgg gtcgtgcatc
    23041 gaacgctgca cggccgtctc gtacgtacgg atctcccggg tgaggacgag catcaggttt
    23101 acgaggaacg cgtcacgcgc cgcgggtccc gccgactggg cgagctggct gatctgccgg
    23161 cgggcggccg gagcgtcccc gaggaccgcc cacagcgtcg ccaggtcgta ccccggcaga
    23221 taccagcccg cgtgctccca gtccaccagc actggaccgg ccggtgagag gagcatgttc
    23281 gacaggaggg aatcgccgtg acagaactgg cccatgccct ggcggccggc cgagtgcgcg
    23341 atgccgtgca ccagtttctg caggtcgccc aggtcccggt cggtgagcag ccccagctcg
    23401 tggtaccggg agatccgtgc cgcgtagtcc agcggggcgt cgaacgtccc ggccggcggc
    23461 cgccacgcgt tgagccggca gatcgcgccg agcgccgccc tgatgtccgc gcgcggcggg
    23521 gcctccagcg gatgccggtt cagcgccgcc acccgtcccg gcatccgctc gatcaccagt
    23581 gtgcagttgt ccgggtccgc cgcgatcaga cgcggcaccc gcaccggcgg ccggtgccgt
    23641 acgaacgagc ggtatgccgc tatttcatgc cggatccgct cggcccacac cggggagtgg
    23701 tccagtaaac acttggccac ggcggtgctg cgccctgtcg taccgaccag gagcacggag
    23761 cgtccgctgc ggcgcagcac ctgcaccgga gcgaactccg gacagatgcg gtgcaccgac
    23821 gtgatcgccg tacgcagctg ggcgccctgg gcgccggaca ggtcgagtct gccgctgagc
    23881 ggttgcgtgc cgagccccgg cacgcgccgt gtccggccgg cgccgagggc gggggccgcc
    23941 gcggggcgcg cggggtcgag gtaggggccg ccgcctccgg ggcgggcgtg cagcgaccgg
    24001 ggtggggcgg acacggagga cgatgctgtg tacatgggcg agacagatcc cttcgtgtgc
    24061 cggcgagtta ccgcgtcacc cgccccggtc acaccggtac accctgggga atgtccctcg
    24121 gcgaccgggt cggggtggcg cgttcctacc tgacacccgg cgcccactgg cacaccatct
    24181 ggcgtgccct ggcgaaccct ggcgaatagt cgctcagcaa ctgtcggacg gttactgtca
    24241 actcagccga gaacctgggg gcttgacgtg agcggacaac ccaacacccg tctgtcggac
    24301 ctgttcggcc tggccggctg gtccaagggc gaactcgcga ggatggtcaa ccggcaggcg
    24361 gcggccatgg gccaccccca gctggcgacc gacacttcga gagtgcggcg gtggatcgac
    24421 atgggagaga tcccgcgcga tccggtgccg cgggtgctgg cagccctgtt caccgagcgt
    24481 ctcggccgtg tcgtgaccat ggaggatctc ggtctggtcc ggcacgggcg tacggggaaa
    24541 cggcagagcg gcgggagtgc ggaacatccc gacggtgtgc cgtgggcgcc cgagcggact
    24601 gccgcggtcc tcaccgaatt cacgggaatg gacctcatgc tcaaccgacg cggcttggtg
    24661 ggtgcgggcg ccgcgctcgc cgcaggatcc gcaatcagca gctccatgca cgagtggctg
    24721 cacaccgatc cggccctcgc ggccgacgct ccggaaaccg accatcccct gcacgccgac
    24781 cccgccgggt tcgaccgcta cgaggccgcc cccatcgggt cgcaggagat cgaggaactg
    24841 gagcgctctg tcgaggtgtt ccgggcctgg gacgcggccc gcggtggcgg cctgcaacga
    24901 aaggctgtcg taggacagct caacgaggtg ggaggcatgc tctcctaccg acatcccgac
    24961 catctgcagc ggcgcctgtg gggcgtcgcc gccaacctcg ccgtcctcgc gggctggatg
    25021 tcgcacgacg tcggcctgga gcccacggct cagaagtact tcatcatcgc cgcgcacgcg
    25081 gcccgagaag gcggtgaccg gccccgcgcg ggcgaggcgc tctcccgagc ggcccgtcag
    25141 atggtgcacc tcggccggcc cgacgacgcg ctcgacctca tgaagctcgc caagtcggga
    25201 tccggcgacg aggtcctgcc ccgtacgcag gccatgctcc acaccatcga ggcctgggcg
    25261 caggcgtcga tgggcaaggg ccaggccatg cggcgcacgc tgggcgaggc ggaggacctc
    25321 ttcgtctcgg acagcggtga cgtgccgccg ccgagttgga tgcagctgtt cgacgaggcg
    25381 gacatgcacg ggatgcaggc tctggcctac cggacactcg ccgagcacga accggctgcg
    25441 gccgccgtcg cgcagcgcca tgcgaaggag gccttggcac tgcgggagaa gggccggaac
    25501 cggtcacaga tcttcgacca catctcgctc gcctcggcct gtttcatcgc cgacgacccc
    25561 gagcaggccg accggtacgc acgactggcc ctgacgtcga tgggttcgaa ctcgtcccat
    25621 cgcacctggg accggctccg tgagatgtac cggctgacgg ggcagtactc cagctatccg
    25681 aagatccacg atctgcggga ggagatcaaa ctctcgatgc ccaagggttc gttgaagcag
    25741 aggggcacca acaacgcacg ggcgtagcgg gcccgtgcgt cgatggctca gccgatggct
    25801 cagccgatga ctcaggtggt gacccgggcg acgaggacgc aggcgtcgtc cgcgcgttcc
    25861 gtctcgccga actcctccac caccgtccgt acgcagtcct gggcggtgcg ggcctcgccg
    25921 aagcgggggg ccaggccgag gagacggctg acggccgcgg cgccttcccc ggtctcgacg
    25981 gtgccaccgg tgtcatcggt gccgatgagg tccgggcgcc cggtgtgggc cgcggccgga
    26041 cggggggacc cctctcgcag gggggccagt ccgtcggtgt gcaggagcag taggtcgccc
    26101 ggctccaggg gctcttccgc ctgcccgtag acggcacccg aggtggcgcc gagcaggacg
    26161 ccggccggcg gggtcagcgt gcgccccgtc ccgttgcgga acagcagcgg ggcggggtgt
    26221 cccgcctgcg cccagacaag ggtccggctc tgcggccggt agcggcagca caccgcgctg
    26281 cccagcgtcg gccgggccga ggcgtcgaac agctggttga gccatgtcat gagccggccg
    26341 ggctcggtgc ccgccacggc catgccgcgc agcgccccga gcagcatcgc cacgcccgag
    26401 gtgacggtga ccccgtggcc ggtgaggtcg cccgcactca acagcgtgtc gccgccgggc
    26461 agttcgaagg cgtcgtacca gtcgccgccg atcagcgcgc tggtcgagga ggggagatag
    26521 cgggcggcca gctccagtgt tcccgggccc tgttcagggc ggagggaacc tcgccagggt
    26581 ggcagaacgg cttcctgcag ctcgaccgcg aggcgatgct cggtctgcgc gacatgccgt
    26641 tgacgctgca gcgagtcgcg ggtctcgctg acggtccgct gactgcgccg cagctcactg
    26701 acgtcacgca gcacggccca catggagacg gtgctgccgt ccacgtcgag cacgggctcg
    26761 cccatcatgt gcacggtccg tacgtcgccg tcgggccgca gcatgcggaa ctcgccgtcg
    26821 atcggcttgg cgtcgatcag acagtccgtg accatcgagg tcagcctcgg acggtcctcg
    26881 tcgaggacga cggagggcag ttcgtcgagg gtgagcgggg gagcggcggg gtcccggccg
    26941 acgatccggt agagctcacc ggaccaactc gcctcgtccg tgaggaggtt ccactcggca
    27001 ctgccgaccc ggctgatcag cgagccgtgc ggggaggacg cggccggcac ggctcgtacg
    27061 gcgggaggcg ccgcttcggg ctcgacgggc acgggccgag ggccgtccct cagctgcgcc
    27121 aagtgcgcgt ccaggtcgtt gagttggtgc atcgccagat cgcacagggc gcgctgccag
    27181 cgtccttccg ggtccgtgcc gtcggtcggc gcgtcgcgtc gtacggcgtc catgtcgccc
    27241 cgcagccgac gcgtctgcga gatgagcgcg tcgaccgagc cgcgcggagg cggctgggcg
    27301 gccgggtggt ccgccgagag atgggacggc atgacgtact ccgatacagg cacggtacga
    27361 ccaaggcaga aggagggacc gttacgactg ttgcacagcc tgcgacgcgc tgtaagggat
    27421 ttggcaacac gcgactcggt catgcctgtg gcgtatgccg cagtccttgc ggagcccctg
    27481 acggggacga tctcagtacg cgggcccgac tttcaagtcg cgggccggac aagtgaattg
    27541 atatggcgcc cggcgtgctc gacgtccagt ggacatgcgt tcggtgagca tatgtgcggg
    27601 tgtcctcgcc tacgcaccag aactcacccc ggccagtcgc agcaccgcgt ccaggccccg
    27661 gtgcgccccc ggggctgctc cggcgggcag cacataggca cgtagtccgg caccggccgc
    27721 cccgccgtcc ttggccggat ggtcgcccac catcagcgtc tcggcggggc tgacccccag
    27781 ttcgcggcag gcgtgcccga agagcaccgg gtcgggtttc tccgtgtcgt gggcgtagga
    27841 gtgcacccac gacgagatgt gctgatcgag accgtggtgc gcgaacgtgg ctcgcaggtc
    27901 ccagcccacg tcactgacca cgccgagtgc gatccccccg ccggtcagcc gcgcgagcgt
    27961 ggacccggtg tccgcgtacg gcacccagtg ctcgggcgcc cgcaactgcg cgtagagcgc
    28021 gtccgcgtgg ggtgccagct ccggcaccga cgcgtaccag gtggtgaagg cgtggcggtg
    28081 tgcccgcgac gacacatcgc gcccgcgctg cgcctcgacc acctgcgggt cggtgagccc
    28141 cgtctccagc ccgtccagta gccggtccat ctcccgctcg ccgacgggct gcctgagcac
    28201 ggtgcggatc cggtccgcgt acgtgccgac ctggaagagc gtgccgccga agtcgaagag
    28261 cacggctcgt acgggggccg gaacccgctc gggggtcgtg gcgcgcaagg ggccctcggg
    28321 gccgcagacc gggagcgggg agcgagtcat gtgatcttcc tacccgctcg gcgcggcagg
    28381 ggcaatgccc gtgtcccacg gctccctgac catgcggccc ccacgacccc accgccctca
    28441 tggcaaggcg cctcactcct ccgagccgca cgagctgccg tcggcaggca gtcgtccgta
    28501 cagcaggaag tcgtcgactt ttcggtgtac gcatttcgag gaggcgtaac cagtgtggcc
    28561 ctcgcccttg ttgtcgagga cgacggccga cgggccgagc cggtccgccg tctccgtggt
    28621 ccagcggtac ggggtcgccg ggtcaccgcg ggtgccgacg aggagcatct ccgacgtgtc
    28681 gacgtcccgt acctcgtcgc ggatgtacga ggtgcccttg gggcggccgt agcacatcag
    28741 ggcctcggcg agccggtacc ggccgaagac cggcgacgcc tgctcgtact tggcgcgcag
    28801 cttgcggagg ttctcggtga tctggtgcgc ggtgggccgg tcgggatcgt cggcgcagtt
    28861 gatggccatc agcgcggccg ggaggttgtc gagggggatg tctccctcgt cgacgaggcc
    28921 tccgtcccag tctccgcttc caccgccgcc ctcgtccctg ttcccgttcc cgttcgcgtt
    28981 cccgttcccg ttcccgtttc tgtcttcgtt ccgggcgtgt ccgccggttc cgggtacctt
    29041 gctgccgccg ctgtggaacc ccatgatgcc ccgcgtgtcc ccgtcctgga ccagggacgt
    29101 gagtgcccgc gagagggtcg gccacagctc cttgctgtag agggcctgcc ccatggcgcc
    29161 caccaggtcc tggccggaga acggtatgcc gaagtcggac ggcaccgggt cctcgtccag
    29221 cgagtggatc agccggacca cctcctcccg ggccgagcgc gggtcctggc cgaacgcgca
    29281 gttgacgtcc tccgtgcacc agtcgaggaa gtcctccagg gcggtctgct ggccctgggc
    29341 gccgatgatg ccctgctcgc tcagcggttc ggtgagggtg tccacgccgt cgaggaccat
    29401 gcggcccgtc ttcttgggga acttcgccgc gtacaccgcg cccagccgcg ttccgtacga
    29461 gaagccgagg tagttgagct tcttgtcgcc cacggccgcg cgcatcacgt cgaggtcgcg
    29521 cgaggcgtcg accgtgccga tgtgctccag cacaggaccc gagtgatccg cgcagtcctt
    29581 ggcgaccttt cgcagcacgt cgagagcggc ccggacgtcg gcgctctcgt ccgcctccga
    29641 ctcggcctcc gcgccgtcgt cggggtcgtc ggggtcgacg tcggtggatc ccatggcctc
    29701 gtccgtgctg tcgccgcagc tcaccgggga gcttcggccg acgccgcgcg ggtcgaaggt
    29761 caccacgtcg tagccattcg tgagacccat gaagtccttg ccgccgtcgg agagttcact
    29821 gactccaggc ccaccgggcc caccgaagtt cagcagcacc gaacctctgg acttgccggt
    29881 cgcccggaac ctggccatgg ccaggtcgag cgtcccgtcg gcggggttcg cgtagtcgag
    29941 gggaaccgtc acctttccgc actgcaggcc ctcgggcagc ccgtcgccgg cacaggccga
    30001 ccacttgatt ctctggtcgt agaaatggga caggtcggaa cggtctgcgg cagccgcggc
    30061 caccgacggc agccctgctc cgagcagggc catcgtcatg gcgcaggtga aggcgcggcg
    30121 tcgttgcgtt ggcagcatca ggcctcccgg gacgtcccgg cccgcagccg ggattccccc
    30181 tcgatcacga taagggggct cctccggcca cgcctctcgg cgagcgaagc ggccacgcag
    30241 gccctatcct gtgccgctcg aaccgcgctt cgaaccgcgc ttcgaaccgc gcttcgatcg
    30301 gtatccgctc gaaggggtgg tcaagggcgg acgggccata acccgcgtgg gttgcccgcg
    30361 tttgaccggt gcgggcgacc gcccgcgacc gtgtctggaa ggcagggaac ctatgaaacg
    30421 ggttgcccga aatggtttga tcatcgcggc cgccgcctcc ggcgccgtgg ccgtgacgat
    30481 gccggcgtac gcggactccg cggccgacgg agcctcggcc cactcgcccg gcgtgatctc
    30541 cggcaacacc cttcacctcc cggtacacgt tccggtgaac gcgtgcggga acaccgtgaa
    30601 cgtggtcgga ctcctcgacc ccgcggcggg caacagttgc gccgacgagg gcgacggtag
    30661 gggcggcggt aaaggccacg gcaagggaag cggcacggca ggcgggcaca agggatccgc
    30721 cggcacggtc gccgagggcg gtgcgaaggg ctcaccgggc ctgatctccg gcaatggtgt
    30781 ggcgctcccg gtcgatctcc ccgtgaacgt caccggcaac tcggtgaatg tcgtcggcat
    30841 cggcaacccc gccgtaggca acgaatccac gaacacgtcc ggcgaccggc cgcaccaccc
    30901 ggccacgccg tcgaagccgc ccgtgaaacc ggccgacgcg gccgacccgg tggagcccga
    30961 ggccgcgccg cgcatcctgc cgcagggagc caccgaggcg accctcgccc gcaccggtac
    31021 ggacctgatg ggcccgacgg tcgccgccgg cgccgcgctg atgctgggcg gagccgcgct
    31081 gtaccgccgc ttccggccca ccgccgccgt acagcggtcc gagcgccggg ccgccgggcg
    31141 ctgacgcgaa cccatgggcg caccggcccg ggccacggtt ttccgcgaac cgtggcccgg
    31201 ggcggtgcgc acaccgccga gacctcctcc ctctcttctt ccccctcttc ccctctcccc
    31261 acgaacggag cgcatcgatg acctcgccga accccgaagg cctcgtcgtc acccaggcct
    31321 cgctcgccga ctggccggtg atccgggcgt gggcggggga cgaggggtgg gaccccgggg
    31381 tgtcggacgg gccgtgcttc ttcgcccagg accccgacgg gttcttcctc ggccggatcg
    31441 acggcgaacc ggtctcggcg atctccgtcg tcaactacgg tgccgagtac gcctttctgg
    31501 gctgttacct cgtccggccg gacctgcgtg gccgcggcta cggaatcgcc acctggaaga
    31561 cggccctggc ccacgcgggc ggacggaccg tgggactcga cggcgtggtc gcacagcagg
    31621 gcaactaccg gcagtcgggg ttcgaactcg cctacaagac gttccggttc gcaggagtcc
    31681 cggcagcgag gtcggccacc gccacagcca cagccaccgc cacagccacc ggtgtccgcg
    31741 gtgccgagaa gagtgacgtc gaggcggtcg tcgcgtacga caggggctgt taccccgccg
    31801 accgtccgca gttcgtggag cgctggctcg gcggcaccgg acaccgggcc ctggtgcgtg
    31861 tcgtcgac
//
