LOCUS       NZ_AP023440            21059 bp    DNA     linear   CON 26-MAY-2024
DEFINITION  Streptomyces aurantiacus strain JCM 4677 chromosome.
ACCESSION   NZ_AP023440
VERSION     NZ_AP023440.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces aurantiacus
  ORGANISM  Streptomyces aurantiacus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 9428393)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye
            Genome Coverage                   :: 62X
            Sequencing Technology :: Illumina HiSeq X Ten; PacBio Sequel II
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014701115.1-RS_2024_05_26
            Annotation Date                   :: 05/26/2024 05:58:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,211
            CDSs (total)                      :: 8,122
            Genes (coding)                    :: 7,928
            CDSs (with protein)               :: 7,928
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 194
            CDSs (without protein)            :: 194
            Pseudo Genes (ambiguous residues) :: 0 of 194
            Pseudo Genes (frameshifted)       :: 69 of 194
            Pseudo Genes (incomplete)         :: 161 of 194
            Pseudo Genes (internal stop)      :: 17 of 194
            Pseudo Genes (multiple problems)  :: 48 of 194
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:48:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8428329
            Orig. end                         :: 8449388
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP023440.1.
            Genome sequencing and analysis were conducted under the Global
            Catalogue of Microorganisms (GCM) 10K type strain sequencing
            project (http://gctype.wdcm.org). The genomic data are also
            available at http://gctype.wdcm.org/sequencing/GCM10017557
            Annotated by DFAST v.1.2.7 (https://dfast.nig.ac.jp).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21059
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="29"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21059
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21059
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11059](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11059)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(230..244)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     gene            2031..3206
                     /locus_tag="IGS71_RS36325"
                     /old_locus_tag="GCM10017557_74110"
     CDS             2031..3206
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433748.1"
                     /locus_tag="IGS71_RS36325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_74110"
                     /product="cytochrome P450"
                     /protein_id="WP_055508669.1"
                     /sec_met_domain="p450 (E-value: 1.6e-21, bitscore: 75.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAGSSPLGAATTLAELTRDPHARLALLREHEPVSWLPELDGWL
                     VTRRDLALSVMRDAETFTVDDPRFSTAQVVGPSMLSLDGAPHARHREPFTAPFRPRAVR
                     EGFASFIEREAGRLITELPPAGAVDLRRAFAGPLAVAVVTEALGLVGTSTATLLSWYDS
                     IVASVSDITAGHAAGPAGTAAYAQLRAAVEATVADRDASSLLGSAAGHLTLPEVASNAA
                     VLMFGGIETTEGMITNALLHLLRNPGQLALVRADIGLLDGAIEESLRLEPGAAVVDRYA
                     TRDTVLGPVTVRRGDLVTVSLAGANRDPAVFPDPDRFDVRRENARLQLAFAHGPHYCLA
                     AHLARLETRIALQYLLERLPALRLDPARPTDAYGLVFRKPLSLHVLWDRPV"
     gene            complement(3172..3819)
                     /locus_tag="IGS71_RS36330"
                     /old_locus_tag="GCM10017557_74120"
     CDS             complement(3172..3819)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474918.1"
                     /locus_tag="IGS71_RS36330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_74120"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_055508667.1"
                     /transl_table=11
                     /translation="MQQKKDAPLRSDAQRNRERILEVAVAELTLCADAPLSMIAKKAGV
                     GQGTFYRNFPNREALVLEIYRHEMQQVTEAATELLCAHEPERALREWMDRLARFAMTKA
                     GLADAIRQATSAPGSPAKPEPTPVASAAALLLRANEEAGTIRPGVTEDDFFLAIAGLWQ
                     LDAHGDWQSRAARLLDLVMDGLRAGAPAGERPAGQPRQQGPVRQDGPTGRAD"
     gene            4110..4724
                     /locus_tag="IGS71_RS36335"
                     /old_locus_tag="GCM10017557_74130"
     CDS             4110..4724
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982979.1"
                     /locus_tag="IGS71_RS36335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_74130"
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="WP_190854182.1"
                     /transl_table=11
                     /translation="MAPAPSSTYSAVTLNINGEKHTLTVDHRTTLLDALRERLDMTGTK
                     KGCDQGQCGACTVLLDNRRAVACLQLAVAAEGREITTIEGVADGDQLHAVQQAFLDLDG
                     YQCGYCTPGQICSAVAVIEEHAAGWPSAVTDDVRPEAGPPPLTAEEIRERMSGNLCRCG
                     AYVSIVQAVARAAEADARARAVDGDRTADSTQAAKHEGAAA"
     gene            4721..5713
                     /locus_tag="IGS71_RS36340"
                     /old_locus_tag="GCM10017557_74140"
     CDS             4721..5713
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011027599.1"
                     /locus_tag="IGS71_RS36340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_74140"
                     /product="xanthine dehydrogenase family protein subunit M"
                     /protein_id="WP_190854184.1"
                     /transl_table=11
                     /translation="MKEFGYQRAADVSGALALLDADPDARFLGGGTNLVDLMKTGVERP
                     GRLVDVRELPLDRIESTEDGGLRVGATVTNSDLAAHPDVRRNYPALTQAVLAGASGQLR
                     NMATVGGNLLQRTRCGYFADVSKPCNKRAPGSGCSAIEGEHHNHAILGASDHCVATHPS
                     DMGVALTAFDAVVDYETVDGPGQLALTDFYLPVGDTPHRETALPPGALITGVTLPPAPV
                     AANSRYRKVRERASYAFAIGSIAAALDVQDGVVREVRLAFGAVASRPWRAHAAEQALTG
                     GPVDAAAFAAAADAELAAARPLPHNGYKVTLMRNLVVAVLSELAEEAGR"
     gene            5710..7839
                     /locus_tag="IGS71_RS36345"
                     /old_locus_tag="GCM10017557_74150"
     CDS             5710..7839
                     /GO_function="GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1293: aldehyde oxidase and xanthine dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994641.1"
                     /locus_tag="IGS71_RS36345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_74150"
                     /product="xanthine dehydrogenase family protein
                     molybdopterin-binding subunit"
                     /protein_id="WP_190854185.1"
                     /transl_table=11
                     /translation="MTTTTTGTRPAQAVGTAHTRVEGPDKVTGAARYAGEIPFTELAHG
                     WLVLSTITRGRIRSVEDAAVLEMPGVLAVLHHGNAPRVDTGYTGMMGMSPDPTIAVFQH
                     DRVPHAGWPVALVVAETSEQAREAAEALVVHYEEEPHNVTFSGEHPDAYPAPGVGGPGV
                     TEKGDLAAELAASAVVLDAEYTTPEEHHNPMEPHAATAHWDGGRLEVVDSNQGTLWVAN
                     ELANLFSLDPASVRVRSEHVGGGFGNKGVRAHQVAAVMAATVLARPVRVVMTRRQMFSL
                     AGYRSPTTQRVRLGADAEGRLRALEHDCLSLTSTVHEFVEAGAGPARVMYDAPAHRTAN
                     RLVRLDVPSPTFMRAPGEAPGSFALESAFDELAEKCGIDPIELRLRNEPAAGPVSGLPF
                     STRNLPACFREGARRFGWADRDPRPGVRRDGRWLLGTGTAAASFFVGAMPSTAAATAEA
                     DGTFTVRINASDIGTGARTALTLIAADALQVPTDRVRVRIGDSDFGPAMIAGGSMGTRS
                     WAWAVTAAADELRERVALSDGIPPEGITVRSDTTDAVGALAQKERHSFGAQFAEVAVDV
                     ATGEVRVRRMLGIFAAGRIINPLTARGQLTGGMIWGISMALHEEAIRDEGTGALYGADL
                     AGYHVATNADVPLIEADWVDDPDPDDPVGIKGIGEVGIVGVAAAIANAVWHATGVRHRS
                     LPIRPDRVLTAGPHA"
     gene            7832..8977
                     /locus_tag="IGS71_RS36350"
                     /old_locus_tag="GCM10017557_74160"
     CDS             7832..8977
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005608.1"
                     /locus_tag="IGS71_RS36350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_74160"
                     /product="XdhC/CoxI family protein"
                     /protein_id="WP_055508659.1"
                     /transl_table=11
                     /translation="MLDIADELARWADEGREFAVATVVGVGGSAPRGPGAALAVDSEGT
                     VIGSVSGGCVEGAVYDLCVQALQDGETVVERFGYSDEDAFAVGLTCGGILDIMVTPVGV
                     HSPVRTVLRSALSAAASGEPRALARVVRGPAELLGRALLVHPDGSYEGSYDNGSAELDR
                     TAAAEARAMLDAGRTGTRDLAEDGTNCPGGLTLLVESNVPPPRMIVFGAIDFAAALVRA
                     GKFLGYHVTVCDARPVFATRARFPEADDLVVDWPHRYLRGTATDGRTVLCVLTHDAKFD
                     IPLLEQALRLPVAFVGAMGSRRTHADRDRKLREVGLSERELSRLRSPIGLDLGARTPEE
                     TALSIAAEIVAARRGGTGVPLTGSGTPIHRDGRQRDAAEAA"
     gene            complement(9022..9930)
                     /locus_tag="IGS71_RS36355"
                     /old_locus_tag="GCM10017557_74170"
     CDS             complement(9022..9930)
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069177.1"
                     /locus_tag="IGS71_RS36355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_74170"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_246596818.1"
                     /transl_table=11
                     /translation="MADIDIDPDSSTDAHLAAAPVPSQSTYQTRVADYWNAEENPVNLE
                     LGKIDDLYHHHYGIGTVDPSVLDGETDAESDGRRDRITAELHRLEQAQAELLASHLGDL
                     SPADRVFDAGCGRGGGSVVAHLRYGCHADGVTISRKQADFANEQARRRNIADKVRYHHR
                     NMLDTGLATGAYAASWNNESTMYVELDLLFAEHARLLRRGGRYVTITGCYNDAYGRASR
                     EVSLINAHYICDIHPRSEYFRAMARNRLVPVHVQDLTGDTVPYWELRRQAGHLVTGIEE
                     TFLDAYRNGSFQYLLIVADRV"
     gene            complement(10001..11059)
                     /locus_tag="IGS71_RS36360"
                     /old_locus_tag="GCM10017557_74180"
     CDS             complement(10001..11059)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018093087.1"
                     /locus_tag="IGS71_RS36360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_74180"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_190854187.1"
                     /sec_met_domain="T1TS (E-value: 9.3e-55, bitscore: 185.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPPVPGPALRLPGPPSLARATTARRAGTVPGLRYRPAPPADPE
                     KAAEIDRRLETWARRLELFPPTWTGDFAGFQFGRAVVLQHPGAISLEHLTAAGKLLLAE
                     NVVDSCYCEEDEGRGGSSRGLGGRLIMAQSALDPYHGTPELEEEWRRGMGADGPLRSYD
                     QALKEYAALATPSQSDRLVHDLARLHLGYLAEAAWSETGYVPRVWEYLVMRQFNNFRPC
                     LSIVDAVDGYELPEALYARPEIQRITALAANATTIVNDLYSFTKELAAGPDHLNLPQAI
                     AANERCGLKAAYLKAVEIHNTVMEAFEEESAALSGLSPLVARYAESLAAWVSGNHEWHA
                     TNSHRYHLPNYW"
     gene            complement(11056..12519)
                     /locus_tag="IGS71_RS36365"
                     /old_locus_tag="GCM10017557_74190"
     CDS             complement(11056..12519)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005613.1"
                     /locus_tag="IGS71_RS36365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_74190"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_246596636.1"
                     /transl_table=11
                     /translation="MSAPESSPDSSDGSAESSPQGAAGAAGDASQFTSLSTRAARQLTT
                     TAKTEPQMQAITSRWLLKMLPWVDVKGGTYRVNRRLQLRVGRGRVQFDQNGADDIKVIP
                     ETLTELPSLRGYSDTAALREIASRFRVRDVRAGQVLCSAGRPVREAYLVVHGRFTRYST
                     GKYGEEQVTGIVTDGDGLGDEAIGRDSPVWLNTVRADTAAVVLALNWDSLARFVERTPS
                     LAAQLAAFAEQQRKPMNRKGEADVPMQAGHVGEPVLAGGFVDYELAPREYELSLTQTVL
                     RVHSRVADLYNSPMNQTQQQLRLAIEEIRERQEWELVNNREFGLLHNVDHAQRVSTFSG
                     PPTPDDLDELLSMRRKTRVFLAHPKGIAAFFRQCNRRGLVPGTVAVEGHEVPAWRGVPF
                     LPCSKIPIGPDHTSSVIALRTGEADQGVVGLYQTGIPEEFQPGLNVRFMGIDTSAIMNY
                     LVTAYYSMAVLVPDAAGILENVQVGRTAE"
     misc_feature    complement(12545..12559)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.84"
                     /tool="antismash"
     misc_feature    12740..12758
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.12"
                     /tool="antismash"
     misc_feature    complement(13050..13063)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.77"
                     /tool="antismash"
     gene            13083..14069
                     /gene="paaA"
                     /locus_tag="IGS71_RS36370"
                     /old_locus_tag="GCM10017557_74200"
     CDS             13083..14069
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="paaA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031683.1"
                     /locus_tag="IGS71_RS36370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_74200"
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaA"
                     /protein_id="WP_055508652.1"
                     /transl_table=11
                     /translation="MTTTHSAEATLPEGSLQEHFDATIARDQRIEPRDWMPDGYRRTLV
                     RQIAQHAHSEIIGMQPEGEWITRAPSLRRKAILFAKVQDEAGHGLYLYSAAETLGADRA
                     DLTERLIEGRQKYSSIFNYPTPTFADVGVIGWFVDGAAICNQVPLCRSSYGPYARAMVR
                     ICKEESFHQRQGYELLMTMMRGTGAQREMVQDSVDRWWWPSLMMFGPPDGDSPNSAASM
                     AWKIKRHTNDELRQRFVDMTVPQAEKLGVTLPDPELRWNVERGHHDFGTPDWSELKRVI
                     GGDGPCNAQRTQRRRSAHEEGAWVRDAATAHAAKQAERAREREGAVA"
     gene            14066..14401
                     /gene="paaB"
                     /locus_tag="IGS71_RS36375"
                     /old_locus_tag="GCM10017557_74210"
     CDS             14066..14401
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="paaB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009326309.1"
                     /locus_tag="IGS71_RS36375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_74210"
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaB"
                     /protein_id="WP_055508650.1"
                     /transl_table=11
                     /translation="MSDSTPGSATPEPGQGAPKGDWPLYEVFVRGKRGLNHVHVGSLHA
                     ADDTMALTHARDLYTRRNEGVSIWVVRSEHIAASTRDEKDPFFAPSADKVYRHPTFYDI
                     PDDVPHI"
     gene            14412..15239
                     /gene="paaC"
                     /locus_tag="IGS71_RS36380"
                     /old_locus_tag="GCM10017557_74220"
     CDS             14412..15239
                     /EC_number="1.14.13.149"
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="paaC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009326306.1"
                     /locus_tag="IGS71_RS36380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_74220"
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaC"
                     /protein_id="WP_055508648.1"
                     /transl_table=11
                     /translation="MSDDHVYLSLAEGHEDDARWAYGTGFEDPLHGVDTTVPAGVDAGS
                     LAADCVALADDALVSAQRLAEWTTRAPELEEEVALANIGLDLLGQARLLYARAGQVDGT
                     GRGEDAYAYFRDAADFRNVRLAELPNGDFAFSVVRLLVLSSWRLAHFEELSAHPDPVLA
                     AVAAKGVKELTYHRQYAAEWVVRLGDGTDESHRRTRRALEQVAPYFGELFTAYDVRDGV
                     VAVLRQVTEAAGLPMPVYRPLPGAGRSGEHTGHLAPLLAELQSVARAHPGATW"
     gene            15245..15757
                     /gene="paaD"
                     /locus_tag="IGS71_RS36385"
                     /old_locus_tag="GCM10017557_74230"
     CDS             15245..15757
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="paaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010043943.1"
                     /locus_tag="IGS71_RS36385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_74230"
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaD"
                     /protein_id="WP_055508646.1"
                     /transl_table=11
                     /translation="MTASTDARRARRVAEQVPDPELPMLTLADLGVLRAVEVTGDGTVV
                     ASLTPTYSGCPAMAEMRADVAARLRGAGYARVEIRTVLDPPWTSDWITPQGRRKLTEHG
                     IAPPGAAPRHAAGPVPLVLAPTRRTVACPRCGAADTEETSRFAATSCKALWRCRVCREP
                     FEYVKEI"
     gene            15757..16935
                     /gene="paaE"
                     /locus_tag="IGS71_RS36390"
                     /old_locus_tag="GCM10017557_74240"
     CDS             15757..16935
                     /EC_number="1.14.13.149"
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="paaE"
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474890.1"
                     /locus_tag="IGS71_RS36390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_74240"
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaE"
                     /protein_id="WP_055508644.1"
                     /transl_table=11
                     /translation="MEGLREEPAASAASAASPANRAAEAPAAAPVRPVPARVRRRPAFH
                     ALRVAAVQPLCEDAAAVSFEIPAELAAEFAFAPGQSLTLRREVDGRDERRSYSICSPAG
                     SAPRIGVRVVPGGLFSAWLVREVRPGDTVQVMAPTGTFTPDLTTPGHHVLVAAGSGVTP
                     MLSIAESVLAADPRSTVTLFYGNRRTDTVMFADELADLKDLYPARFQLAHVLSREPREA
                     EVLSGRLDADRLSALVGSLVDVAAVDHWWLCGPHGMVLDAQRVLTGLGVHGDRVHRELF
                     YADDEPVREVRHEEAALRGPVSQVTVTLDGRSTTSALVRDRSILEGAQRTRPDLPFACK
                     GGVCGTCRALITDGKADMRRNFALEDAEVAAGYVLTCQSYPVSETLTVDYDV"
     misc_feature    17108..17126
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.52"
                     /tool="antismash"
     misc_feature    17124..17142
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 23.9"
                     /tool="antismash"
     gene            17178..18542
                     /locus_tag="IGS71_RS36395"
                     /old_locus_tag="GCM10017557_74250"
     CDS             17178..18542
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1285: ferredoxin fdxC"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019327819.1"
                     /locus_tag="IGS71_RS36395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_74250"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_055508642.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 8.7e-08, bitscore:
                     30.6, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRPLRVAIVGAGPAGIYAADALLKSAVAVEPGVSIDLFERMPAP
                     FGLIRYGVAPDHPRIKGIITALHQVLDKPQIRLFGNVDYPGDINLDDLRAFYDAVIFST
                     GATADRALDIPGIGLDGSHGAADFVSWYDGHPDVPRTWPLEAEKVAVLGVGNVALDVAR
                     ILAKTAEELLPTEIPPNVHEGLKANKAVEVHVFGRRGPAQAKFSPLELRELDHSPNIEV
                     IVDPEDIDYDDGSIATRRGSKQADMVAKTLENWAIRDVGDRRHKLFLHFFESPTEILGE
                     DGKVVGLRTERTALDGTGNVKGTGEFKDWDLGAVYRAVGYLSDKLPKLPWDVDSGTVPD
                     NAGRVIEETGEHLRSTYVTGWIRRGPVGLIGHTKGDANETVASLLDDHRNGRLQTPVSP
                     DPESVDAFLADRNVRFTTWEGWYRLDAAEKALGEPQGRERVKLVEREDMIEASGA"
     misc_feature    18545..18554
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.41"
                     /tool="antismash"
     gene            18671..19372
                     /locus_tag="IGS71_RS36400"
                     /old_locus_tag="GCM10017557_74260"
     CDS             18671..19372
                     /NRPS_PKS="Domain: PKS_KR (7-105). E-value: 6e-09. Score:
                     28.0. Matches aSDomain:
                     nrpspksdomains_IGS71_RS36400_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020117058.1"
                     /locus_tag="IGS71_RS36400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_74260"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_190854190.1"
                     /transl_table=11
                     /translation="MTAIEGSVVLVTGGGRGIGKALVEGLFERGAKKVYATARDPRTIT
                     DTRAVPLALEVTDPASVAAAAEQAGDVTVLINNAGVSVNASFLDAPVADVRRDFETNFY
                     GPLLTARAFVPVIERNGGGHILNVHSVLSWIGLAGSYSASKAALWSQTNSLRLDLAPRG
                     IGVTGLHVGYVDTDMTAAIDAPKSSPVDVAAQALDGIESGAFEVLADDLSRRVKSGLAA
                     DLSVLYPQLAA"
     CDS_motif       18692..18772
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IGS71_RS36400_0001"
                     /evalue="4.40E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="IGS71_RS36400"
                     /protein_end="34"
                     /protein_start="7"
                     /score="19.4"
                     /tool="antismash"
                     /translation="VVLVTGGGRGIGKALVEGLFERGAKKV"
     aSDomain        18692..18985
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IGS71_RS36400_PKS_KR.1"
                     /evalue="6.00E-09"
                     /label="IGS71_RS36400_PKS_KR.1"
                     /locus_tag="IGS71_RS36400"
                     /protein_end="105"
                     /protein_start="7"
                     /score="28.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VVLVTGGGRGIGKALVEGLFERGAKKVYATARDPRTITDTRAVPL
                     ALEVTDPASVAAAAEQAGDVTVLINNAGVSVNASFLDAPVADVRRDFETNFYG"
     gene            19431..20003
                     /locus_tag="IGS71_RS36405"
                     /old_locus_tag="GCM10017557_74270"
     CDS             19431..20003
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005473850.1"
                     /locus_tag="IGS71_RS36405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_74270"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_190854191.1"
                     /transl_table=11
                     /translation="MATSTDKTSTRDRLLDAAMELFYRDGVSLGVEALCRAAGVSKRSM
                     YQLFASKDEVLAASLERRAPEYGRRLRPGPDDPRSPRERILYVFEQLEQASTEDDYRGC
                     PYLSAMVELKDPEHPASVVALRVKGTLTEAFRVDAERGGARDPELLARQLTLIFDGASA
                     RAGAKAETLQGLTTTTATALLDAAGVK"
     gene            complement(20188..20664)
                     /locus_tag="IGS71_RS36410"
                     /old_locus_tag="GCM10017557_74280"
     CDS             complement(20188..20664)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571009.1"
                     /locus_tag="IGS71_RS36410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_74280"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_190854193.1"
                     /transl_table=11
                     /translation="MAVDDLDTRILRLLLEQPSTSVREYARVLGVARGTLQARLDRLER
                     DGVITGTGPSLSPAALGHPVLAFVHIEVTQGNLDDVGDALAAVPEIIEAFSITGGGDLL
                     TRVVARDNGHLEDVIQSLISLPGVVRTRTEVVLRERVPQRVLPLVESIGRTGRG"
     misc_feature    complement(20891..20906)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.95"
                     /tool="antismash"
     misc_feature    complement(20892..20906)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 20.44"
                     /tool="antismash"
ORIGIN
        1 gcagcgttac gaggccgagg tcgaggccga ggtcgaggct ggaggctccg tctcccgctg
       61 acggcgcacg ccgttcggga acggctcggg ccgctggaac gcggccggct gtccgccacc
      121 gcggtggagg cactgtgggc ggaccgggac gcggcaggca ccacggacgc ggggagcccg
      181 cggatcacgg tggcggccct gccgaacgag gcggacgcgg tggcctacct ggccgaccgg
      241 gtcgcggaag ccgggtctct cgtcgacctc gaccgtgcgg tcgccgagct gacggccgcg
      301 gcgcagcggc tgcatcccga ctccgagggc agaggagtgc tccggtggtg ccgggcggcc
      361 ggccacctcg tcgagcggcc ggccgaccgg gtcgccgccc tccaccggta tgcccgggcc
      421 gcctacaacg cgggggacca ccggaccgcc cggaccatcg ccgagtcgat cctgcgcaac
      481 ctggcggacg tcctcggccc gcgggaactg caggccaccg cggccctctt cacggcggcc
      541 accggcaacg acctggactg gcgggcgctg tcccggctgg ccacggcgca gtggtgggac
      601 gagttgcggc tgcccgccct ggtcaccgtg accggccggg ccctggccct cggccagttg
      661 gagaggtggc acgaactgct cgacctgctg tcacggaccg agcggatatg ggccaccgat
      721 gcccacgccc gggtgatgcc cgcccacttc cgcgccgtgg cggaactggc tctcggccgg
      781 ccggagcggt tccgggagtc actggccctg ccggaggcgt cgtacctcga cgccggccac
      841 gcgtacgcgc tcgccaccgc catgttcgac gaactgctca gcggccggga cctgcgagcg
      901 gcgcaggccc tgctgaccgc acagggcctg acatccgagg tgctgccccc ggccgggctg
      961 ttcctctggc gccacctcca gggccggtgg gacgaggccc tggaggtggc ccgctggatg
     1021 ctggcgaaca accggaccag cacccccgcg gcggacagcc acctgattcc cgcgcggacc
     1081 gcggccatcc ttctcgcccg gggccgcacc acgagcgccc gccgcctcgt cgacagcgcg
     1141 cgcggccgtg ccgagggccc gctggagtac tcactggacg ccgccgaggc ggaggtgctg
     1201 cggaccctcg gcgatgcgac cggggccgag aaggtgctgc gccgcggcct ggacgcggcg
     1261 gacgcgaacg gacacgtcgc aggcaccgac gaactgtggg cctcactcgt cgaggtacac
     1321 acggaggagg gacgcgcggg ccaggcggcg gactgcctgg cacgcctccg acggatctcc
     1381 gaccgcacgg gcagcggcag gacacggctg aggtatctgc tcgcgtcggc ccgggtcctg
     1441 cggcaggacg gccgtcccgg cgccgctcgc gagcacctgc gggaggccgt ggagctggcg
     1501 cgttcgcgca gccagccggt cgagacggcg gtgaccctcg tcgccgcagc cgatgcgggc
     1561 gtgggtccgc ccgcactgct gcacgaggcg tacgagctgt tcggcgggag cggtgccgcg
     1621 ctgtcgcgct tccgcaccag ggccgccatg cgggaggcgg gaatcaccgt tcccggccgc
     1681 aagcaggcca ccaccgagaa cgagcgactg ctcgccaccc tgatcgccga agggctcacc
     1741 aaccgccaga tcgccacggt gctgcggctc agtgaggacg cggtcgccaa ccgcctgacc
     1801 cggctcttcg cacgcaccgg gctccggtcc cgtaccgagg tggtcacggc ggtgctcacc
     1861 gactaccgcg tccaccgcct cgcggcggaa gcgtaggagc cccgcgccgc cccgcgccga
     1921 ggaggcggct gagcagggcc cgaagcgcgg ttgttagcct tgaatgtgat cgatcacccc
     1981 atactcgccc ggctctcgct cgacgggacg tcacccgccc ggctctcgcg atgagcaccg
     2041 ccggttcctc tccgctcggt gccgcgacca cgctcgccga actcacccgg gacccccacg
     2101 cacgactggc gctgctccgt gagcacgagc ccgtgtcctg gctgcccgag ctggacggct
     2161 ggctggtgac ccgccgtgac ctcgcgctca gcgtgatgcg ggacgccgag accttcacgg
     2221 tcgacgaccc ccggttctcc accgcacagg tcgtcggacc gagcatgctg tccctggacg
     2281 gagccccgca cgcccgccac cgtgagccgt tcaccgcgcc cttccgcccc agagcggtgc
     2341 gtgagggctt cgcctcgttc atcgagcggg aggccggccg gctcatcacc gaactgccgc
     2401 cggccggtgc cgtcgacctg cgacgtgcct tcgccggtcc gctcgcggtc gccgtcgtga
     2461 ccgaggcgct cggcctggtc ggcacgagta cggccacgct gctctcctgg tacgactcca
     2521 tcgtggcgtc ggtctcggac atcaccgccg gacacgcggc ggggcccgcc ggcaccgccg
     2581 cgtacgccca gctgcgggcg gccgtggagg ccaccgtcgc cgaccgggac gcgtcgtcgc
     2641 tcctcggctc cgccgccggg cacctgaccc tgcccgaggt ggcgtccaac gccgcggtcc
     2701 tgatgttcgg cggcatcgag accaccgagg gcatgatcac caacgcgctg ctgcatctgc
     2761 tgcgaaaccc cggtcaactc gccctcgtcc gggccgacat cggcctgctg gacggcgcga
     2821 tcgaggagtc actgcgcctt gaaccgggcg ccgcggtcgt ggaccgctat gccacccggg
     2881 acaccgtcct cggcccggtc accgtccgcc ggggcgacct ggtcacggtc tccctggccg
     2941 gggccaaccg cgacccggcc gtctttcccg accccgacag gttcgacgtc cgccgcgaga
     3001 acgcgcgact ccaactggcc ttcgcccacg gcccgcacta ctgcctcgcc gcgcatctgg
     3061 cccgcctgga gacccgtatc gcgctccagt acctgctcga acgccttccc gcgctgcggc
     3121 tcgacccggc tcgccccacg gacgcgtacg gtctggtctt ccgtaagccg ctcagtctgc
     3181 acgtcctgtg ggaccgtcct gtctgaccgg tccttgctgt ctgggctgtc cggccggtct
     3241 ttcaccggcc ggggcccccg cgcgcagtcc gtccatgacg aggtccagga ggcgggccgc
     3301 gcgtgattgc cagtctccat gggcatcgag ctgccagagg ccggcgatgg cgagaaagaa
     3361 gtcgtcctcg gtgacacccg ggcggatggt gccggcctcc tcgttggcgc ggagcaggag
     3421 tgccgccgcg gacgccaccg gagtgggctc cggtttcgcc gggcttcccg gcgcactcgt
     3481 ggcctgtcgg atcgcgtccg ccagacccgc cttggtcatg gcgaaccggg cgagacggtc
     3541 catccactcg cgtagcgccc gctcgggctc atgggcgcag agcagctcgg tcgcggcctc
     3601 ggtgacctgc tgcatctcgt ggcggtagat ttcgaggacg agcgcctccc ggttcgggaa
     3661 attgcggtag aacgtgccct gcccgacgcc cgccttcttg gcgatcatgc tgagcggggc
     3721 gtccgcgcag agcgtcagct cggccacggc cacttccagg atgcgctcac ggtttcgctg
     3781 cgcgtcggag cgcagaggtg cgtccttctt ctgctgcact cgtcctcctc acgggttcgt
     3841 ggccgaatcc cgtccttgct aagcggacaa ctgtccatta cgttttgcgg tgagcggaca
     3901 actgtccact tagggccacc ttactagtgg gtgacccctg tggacagtct tcccccccac
     3961 cggtgcctcc ccccgagacc tcttcgaacc tctccgaacc tctctgaacc cctccgaatt
     4021 cttcttcccg atacgtcttg cgtttccgtt ctctctgcct gccggaccgt ccgcgcgatg
     4081 tggtccggga atgcgaaaga aggctgatca tggcccccgc gccctcgtcg acgtacagcg
     4141 ccgtcacctt gaacatcaac ggcgagaagc acacgctgac cgtcgaccac cgcaccaccc
     4201 tgctcgacgc cctgcgcgag cgcctcgata tgaccggcac caaaaagggc tgtgaccagg
     4261 ggcaatgcgg cgcctgtacg gtcctgctcg acaaccgccg ggccgtcgcc tgtctgcaac
     4321 tggcggtggc ggccgaaggc cgggagatca ccaccatcga aggcgtcgcc gacggcgacc
     4381 aactgcacgc cgtacagcag gcgttcctcg acctcgacgg ttaccagtgc gggtactgca
     4441 cacccggcca gatctgttcg gccgtcgcgg tgatcgagga gcacgccgcc ggctggccga
     4501 gcgccgtcac cgacgacgta cgccccgaag cggggccacc acccctgaca gccgaggaga
     4561 tacgggagcg gatgagcggc aacctgtgcc gctgcggcgc gtacgtgtcc atcgtccagg
     4621 cggtcgcccg cgcggccgag gccgatgcgc gcgcccgggc cgtggacgga gaccggaccg
     4681 cggacagcac gcaggccgcg aagcacgagg gagcggcagc atgaaggagt tcggatacca
     4741 gcgcgccgcc gacgtctccg gcgccctcgc actgctcgac gccgacccgg acgcccgctt
     4801 cctcggcggc ggcaccaatc tcgtcgacct gatgaagacc ggcgtcgaac ggcccggccg
     4861 actcgtcgac gtacgcgaac tcccgctgga ccggatcgag tcgaccgagg acggcgggct
     4921 gcgcgtcggc gcgaccgtca ccaacagcga cctcgccgcg caccccgacg tgcgccgcaa
     4981 ctacccggcc ctgacccagg cggtgctggc cggcgcctcc gggcagctgc gcaacatggc
     5041 gaccgtcggc ggaaacctgc tccagcgcac ccgctgcggc tacttcgccg acgtgtccaa
     5101 gccgtgcaac aagcgggccc ccggcagcgg ttgctccgcg atcgaggggg agcaccacaa
     5161 ccacgcgatc ctgggcgcct ccgaccactg cgtggccacc cacccctccg acatgggggt
     5221 ggcgctgacg gccttcgacg ccgtcgtcga ctacgaaacc gtggacgggc cgggccagtt
     5281 ggccctcacc gatttctatc tgccggtggg tgacaccccg caccgggaga ccgccctgcc
     5341 gccgggcgcg ctgatcaccg gcgtcaccct gccgcccgcc ccggtggcgg ccaactcccg
     5401 ctaccgcaag gtgcgcgagc gggcctcgta cgccttcgcg atcggctcga tcgccgccgc
     5461 gctcgacgtc caggacggcg tcgtacgcga ggtgcgcctg gccttcgggg cggtcgcgtc
     5521 ccggccgtgg cgggcccacg cggccgaaca ggccctgacc ggggggccgg tggacgccgc
     5581 ggccttcgcc gcggcggccg acgccgaact ggcggccgcc cggccgctgc cgcacaacgg
     5641 atacaaggtg accctgatgc gcaacctcgt cgtggccgtg ctgagcgaac tcgccgagga
     5701 ggccggccga tgaccaccac cacgaccgga accaggccgg cgcaggccgt cggcaccgcg
     5761 cacacccgcg tggagggccc cgacaaggtc accggagccg cccgctacgc gggagagatc
     5821 cccttcaccg aactcgccca cggatggctg gtgttgtcga cgatcacccg tggccgcatc
     5881 cgctcggtcg aggacgccgc ggtcctggag atgccgggcg tcctcgccgt cctgcaccac
     5941 gggaacgccc cgcgggtcga caccggctac acgggcatga tggggatgag cccggacccg
     6001 accatcgccg tcttccagca cgaccgggtg ccacacgccg gatggccggt ggcgctggtc
     6061 gtcgccgaga cctccgagca ggccagggag gccgccgaag cgctggtggt gcactacgag
     6121 gaggagccgc acaacgtcac cttctccggt gagcacccgg acgcgtaccc ggcccccggc
     6181 gtcggcggac cgggagtgac ggagaagggg gacctggcag ccgaactggc cgcgtccgcc
     6241 gtcgtcctgg acgccgagta caccacgccg gaagagcacc acaacccgat ggagccccac
     6301 gcggcgacgg cccactggga cggcggccgg ctggaggtcg tggactccaa ccagggcacg
     6361 ctgtgggtcg cgaacgaact cgcgaatctc ttctcgctcg atccggcctc ggtgcgggtc
     6421 cggtccgagc acgtcggcgg cgggttcggg aacaagggcg tccgcgcgca ccaggtggcc
     6481 gccgtgatgg cggcgaccgt cctggcgcgc cccgtccgcg tcgtcatgac gcgccgccag
     6541 atgttctcgc tcgccggcta ccgcagcccc accacccagc gggtccggct cggcgccgac
     6601 gccgagggac gcctgcgcgc gctggagcac gactgcctga gcctcacctc gaccgtgcac
     6661 gagttcgtcg aggcgggcgc cggtccggcg cgggtgatgt acgacgcccc cgcccaccgc
     6721 accgccaacc ggctcgtccg gctcgatgtg ccgagtccga cgttcatgcg cgctcccggc
     6781 gaggcacccg ggtccttcgc cctggagtcg gcgttcgacg aactcgccga gaagtgcggc
     6841 atcgacccga tcgagctgcg cctgcgcaac gagcccgcgg ccgggccggt ctccgggctg
     6901 ccgttcagca cccgcaacct gcccgcctgc ttccgtgagg gcgcccgcag gttcggctgg
     6961 gccgaccggg acccgcgtcc gggcgtgcgc cgggacggcc gctggctgct cggcaccggg
     7021 acggcggcgg cctccttctt cgtgggagcg atgccgtcca cggcggccgc gaccgcggag
     7081 gccgacggca ccttcaccgt gcggatcaac gcctcggaca tcggaaccgg ggcgcggacg
     7141 gcgctcaccc tgatcgccgc cgacgccctt caggtgccga ccgaccgggt gcgtgtgcgg
     7201 atcggcgaca gcgacttcgg cccggcgatg atcgccggtg gttcgatggg cacccggtcg
     7261 tgggcctggg cggtcaccgc cgcggccgac gaactgcggg agcgggtcgc cctgagcgac
     7321 ggcatcccgc cggagggcat cacggtacgg tcggacacca ccgacgccgt cggagccctc
     7381 gcgcagaagg aacggcactc gttcggcgcg cagttcgccg aggtcgccgt ggacgtggcc
     7441 accggagaag tgcgggtacg tcgcatgctc ggcatcttcg ccgcgggacg gatcatcaac
     7501 ccgctcacgg cccgcggcca gctcaccggc gggatgatct ggggcatctc catggccctg
     7561 cacgaagagg ccatcaggga cgagggcacc ggcgcgctct acggcgccga cctcgcgggc
     7621 taccacgtcg ccaccaacgc cgacgtgccg ctcatcgagg cggactgggt ggacgacccg
     7681 gacccggacg acccggtcgg gatcaagggc atcggcgagg tcggcatcgt gggggtcgcg
     7741 gcggcgatcg ccaacgccgt ctggcacgcg accggcgtac gccaccgcag cctgcccatc
     7801 cggcccgacc gcgtcctcac ggcaggcccg catgcttgac atcgccgacg agctggcccg
     7861 ctgggccgac gagggacggg agttcgccgt cgccaccgtc gtgggcgtcg gcggcagcgc
     7921 gccgcgcggt ccgggcgcgg ccctcgccgt cgacagcgag ggcacggtca tcggctcggt
     7981 ctccggcggc tgtgtggaag gcgcggtgta cgacctgtgc gtccaggcgc tccaggacgg
     8041 cgagaccgtc gtggaacgct tcggatacag cgacgaggac gccttcgcgg tcgggctgac
     8101 ctgcggcggg atcctcgaca tcatggtcac cccggtcggc gtgcactcgc ccgtccgtac
     8161 ggtgctcagg tcggcgctct cggccgccgc ctcgggcgaa cccagggccc tggcccgggt
     8221 cgtccgcggc ccggccgaac tcctgggcag ggccctgctg gtgcaccccg acgggtcgta
     8281 cgaggggtcg tacgacaacg gctccgcgga gctggaccgg acggccgcgg ccgaggcgcg
     8341 ggcgatgctg gacgccggac gcaccggcac ccgcgacctc gcggaggacg gcacgaactg
     8401 ccccggcggc ctcaccctgc tcgtcgagtc gaacgtgccg cccccgcgca tgatcgtgtt
     8461 cggtgcgatc gacttcgcgg cggcgctcgt ccgggccggc aagttcctcg gctaccacgt
     8521 gacggtgtgc gacgcccgtc ccgtgttcgc cacccgggcc cgcttccccg aggccgacga
     8581 cctcgtcgtc gactggccgc accgctatct gcggggcacg gcgaccgacg ggcgcacggt
     8641 cctgtgcgtg ctcacccacg acgccaagtt cgacatcccc ctgctggagc aggccctgcg
     8701 gctgccggtc gcgttcgtcg gggcgatggg ctcgcgcagg acccacgcgg accgtgaccg
     8761 gaaactgcgt gaagtcggcc tgagcgagcg ggagctgtcc cggctcaggt cgccgatcgg
     8821 cctcgacctc ggggcccgta cgcccgagga gaccgccctg tccatcgcgg cggagatcgt
     8881 ggcggcccgg cgcggtggca cgggcgtccc gctcaccggc tcgggaacgc cgattcaccg
     8941 cgacgggagg cagcgggacg cggcggaggc cgcgtagccg gccccggccc cggcagccga
     9001 gccggggccc cgtcggcccc ctcagacccg gtcggccacg atgagcaggt actggaagct
     9061 gccgttgcgg tacgcgtcca ggaacgtttc ctcgatgccg gtgaccagat ggcccgcctg
     9121 ccggcgcagc tcccagtagg ggacggtgtc gcccgtgagg tcctgcacat ggacgggtac
     9181 gagccggttg cgggccatcg cccggaagta ctccgagcgt gggtggatgt cgcagatgta
     9241 gtgggcgttg atgagcgaca cctcacggga ggcccgcccg tacgcgtcgt tgtagcagcc
     9301 ggtgatcgtc acatagcggc cgccgcggcg cagcaaccgg gcgtgctcgg cgaagagcag
     9361 gtccaactcc acgtacatgg tggactcgtt gttccaggaa gccgcgtacg cgccggtggc
     9421 caggccggtg tcgagcatgt tccggtggtg gtagcgcacc ttgtcggcga tgttccgcct
     9481 gcgggcctgc tcgttggcga agtcggcctg tttcctggag atcgtcaccc cgtcggcgtg
     9541 gcagccgtac cgcagatggg ccaccacgct gccgccgccg cgcccgcatc cggcgtcgaa
     9601 gacccggtcg gcgggggaga ggtcaccgag atgggaggcg agcagctcgg cctgggcctg
     9661 ctccagccgg tgcagctcgg cggtgatccg gtcgcgacgc ccgtcgcttt cggcgtcggt
     9721 ctccccgtcg agtacggacg ggtcgacggt tccgatgccg tagtggtggt ggtacagatc
     9781 gtcgatcttc ccgagttcga ggttgaccgg gttctcctcg gcgttccagt agtccgccac
     9841 gcgggtctgg tacgtcgact ggctcggcac cggcgctgcc gcgaggtggg cgtcagtgct
     9901 ggaatcgggg tcgatgtcga tgtcggcgat ggtcacgggg cactcctcgt ggggcggtgg
     9961 cgctgtggcg cggtggtgat ggaccggggg cggacggcgg ttaccagtag ttcggcaggt
    10021 ggtagcggtg ggagttggtg gcgtgccatt cgtggttgcc ggacacccac gcggccaggc
    10081 tctcggcgta gcgcgcgacg aggggcgaga ggccggacag ggccgcggac tcctcctcga
    10141 acgcctccat gaccgtgttg tggatctcga cggccttcag ataggcggcc ttcagtccgc
    10201 accgctcgtt ggcggcgatg gcctggggca gattcagatg gtcggggccg gcggccagct
    10261 ccttggtgaa ggagtacagg tcgttgacga tggtggtggc gttggcggcg agcgcggtga
    10321 tccgctggat ctcgggccgg gcgtacaggg cttcgggcag ttcgtagccg tccacggcgt
    10381 cgacgatcga caggcagggc cggaagttgt tgaactgccg catcaccagg tactcccaga
    10441 cccgcggcac gtagccggtc tcggaccagg cggcctccgc gaggtacccc aggtgcagcc
    10501 gggccaggtc gtgcacgagc cggtcgctct ggctgggtgt ggcgagggcg gcgtactcct
    10561 tcagggcctg gtcgtacgag cggagcggcc cgtcggcgcc catgccgcgg cgccactcct
    10621 cctccagctc gggtgtgccg tggtacgggt cgagcgccga ctgggccatg atcagccgtc
    10681 cgccgagacc gcgcgacgat ccgcccctgc cctcgtcctc ctcgcagtag caggagtcga
    10741 cgacgttctc ggcgagcagc agtttcccgg ctgccgtgag gtgttcgaga ctgatcgcgc
    10801 cggggtgctg gagcacgacg gcgcggccga actggaaccc ggcgaagtct cccgtccacg
    10861 tagggggaaa cagctccagc cggcgtgccc aggtctccag cctgcggtcg atctccgcgg
    10921 ccttctccgg gtccgcgggc ggggcgggcc ggtaccgcag cccgggaacc gtgccggccc
    10981 gccgggcggt ggtggcgcgg gcgagactcg gcggcccggg cagccggagc gccggaccgg
    11041 gtacgggcgg tgagctcatt ccgcggtccg cccgacctgg acgttctcca ggattcccgc
    11101 cgcgtcggga acgaggaccg ccatcgagta gtaggcggtg accagatagt tcatgatcgc
    11161 gctggtgtcg atgcccatga accgcacgtt gaggcccggc tggaactcct cgggaatgcc
    11221 ggtctggtac agcccgacga cgccctggtc ggcctctccg gtgcgcaggg cgatgacgct
    11281 gctcgtgtgg tcggggccga tcggaatctt gctgcagggc aggaagggaa caccacgcca
    11341 cgcggggacc tcgtgtcctt cgacagcgac cgtgccgggc acgagaccgc gccggttgca
    11401 ctgccggaag aacgccgcga tccccttcgg gtgggccagg aacacccggg tcttgcggcg
    11461 catcgacagg agttcgtcga ggtcgtcggg ggtcggggga ccggagaagg tgctgacgcg
    11521 ctgggcgtgg tcgacgttgt gcagcagacc gaactcgcgg ttgttgacca gctcccactc
    11581 ctggcgttcg cggatctcct cgatggccag gcgcagttgc tgctgggtct ggttcatcgg
    11641 gctgttgtag aggtccgcga cccggctgtg gacgcgcagg acggtctggg tgagcgacag
    11701 ttcgtactcg cgcggggcga gttcgtagtc gacgaagccg ccggcgagga ccggctcgcc
    11761 cacgtgccct gcctgcatgg ggacatcggc ctcgcccttg cggttcatgg gcttgcgctg
    11821 ctgctcggcg aacgcggcca gttgggcggc gagggagggg gtgcgctcca cgaaccgcgc
    11881 gaggctgtcc cagttcaggg ccagcaccac ggccgcggtg tcggcccgca ccgtgttcag
    11941 ccacaccgga ctgtcccggc cgatggcctc gtcgcccagt ccgtcgccgt ccgtgacgat
    12001 cccggtcacc tgctcctcgc cgtacttgcc ggtgctgtag cgggtgaacc ggccgtggac
    12061 gacgagatac gcctccctga cgggccggcc ggcgctgcac aggacctgtc cggcacgtac
    12121 gtcccgcacc cggaaacggg aggcgatctc ccgcagggcc gccgtgtcgg agtagccgcg
    12181 cagggaaggc agttcggtga gtgtctcggg gatgaccttg atgtcgtccg cgccgttctg
    12241 gtcgaactgc acccggccgc ggccgacgcg caactgcagt cgccggttca cccggtaggt
    12301 gccgcccttg acgtccaccc acggcagcat cttgagcagc cagcgcgagg tgatggcctg
    12361 catctgcggt tcggtcttgg cggtggtggt gagctgccgt gcggcccggg tgctgaggct
    12421 ggtgaactgc gacgcgtcgc cggcggctcc ggcggcgcct tggggggagc tttcggcgga
    12481 accgtcagaa ctgtcggggg agctttccgg ggcagacaca tgtcctccca atacgtgatc
    12541 ggtcatcggt atacgtgatc ggtcgtgggt cgatacgcac gaaggcgaga ggtgagaagc
    12601 gagagggggc ggccgtcggt gacccgggct ccggacggct gggttcacgg aggcggtgga
    12661 ggtcgaggac gggttccggg gatcgggccg ccggggcggc ggccgtgggg ccactgcgga
    12721 cggctgggca gtgcgtgctg cctgtaaagc caaacagccg cgggtggcgg ccgggaaccg
    12781 cgtgaaaggg gcgtgttcgc gcctcggaag tgaagatccg ccgtacgggg cgggacgccg
    12841 gcgccggtgt gctcccgcgc cggtcgcagc ccccctgccc cggcacacag ggcgcgcgag
    12901 cggctcggaa ccgccgactc cgcaagccct gataagcagc tcatcagccc ttctgccgtt
    12961 cgaccccgca tccggccctg gcctcggtcc gaccccgctt gatcgtgccc gggtcttgcc
    13021 gggtcgccgg aaaggcgtca cactgatacc gaacgaatgg tcggtagggg aagctggtat
    13081 cgatgaccac gacacactcg gccgaggcga ccctcccgga ggggtcgttg caggagcact
    13141 tcgacgcgac gatcgcccgg gaccagcgga tcgagccccg cgactggatg cccgacggtt
    13201 accgcaggac gctcgtccgg cagatcgcgc agcatgcgca ctcggagatc atcggcatgc
    13261 agccggaggg cgagtggatc actcgcgccc cgtcgctgcg ccgcaaggcc atcctgttcg
    13321 cgaaggtcca ggacgaggcc gggcacggtc tgtacctgta ctcggccgcc gagacgctgg
    13381 gcgccgaccg cgcggacctg accgagcggc tgatcgaggg gcgccagaag tactcgtcga
    13441 tcttcaacta cccgacaccg accttcgccg acgtcggagt gatcggctgg ttcgtggacg
    13501 gtgcggcgat ctgcaaccag gtgccgctgt gcaggagttc gtacgggccc tacgcgcgcg
    13561 cgatggtgcg gatctgcaag gaggagtcgt tccaccaacg gcagggctac gagctgctga
    13621 tgaccatgat gcgcggcacc ggggcgcagc gggagatggt ccaggactcg gtggaccgct
    13681 ggtggtggcc ctcgctcatg atgttcggcc cgcccgacgg cgactcgccc aactcggcgg
    13741 cctcgatggc ctggaagatc aagcggcaca ccaacgacga actgcgtcag cggttcgtcg
    13801 acatgaccgt cccgcaggcc gagaagctcg gcgtgacgct cccggacccg gagctgcgct
    13861 ggaacgtgga gcgcggccac cacgacttcg gcacccccga ctggtccgag ctgaagcggg
    13921 tcatcggcgg cgacggaccg tgcaacgcgc agcggacgca gcgccgcagg tccgcccacg
    13981 aggagggcgc gtgggtacgg gacgcggcca cggcccacgc ggccaagcag gcggagcgcg
    14041 cgcgtgagcg ggaaggagcg gtggcatgag cgactccacc ccgggaagcg ccacgccgga
    14101 gcccggccag ggcgcgccga agggcgactg gccgctgtac gaggtcttcg tgcgcggcaa
    14161 gcgcgggctg aaccacgtcc acgtgggctc cctgcacgcg gccgacgaca ccatggccct
    14221 cacccacgcc cgcgacctct acacccgccg caacgagggc gtctcgatct gggtggtgcg
    14281 ctcggagcac atcgccgcgt ccacgcgcga cgagaaggac ccgttcttcg cgccgagcgc
    14341 cgacaaggtc taccgccacc cgaccttcta cgacatcccc gacgacgtcc cgcacatctg
    14401 aggagcaggg catgagcgac gaccatgtct acctgtccct cgccgagggg cacgaggacg
    14461 acgcccgctg ggcgtacggc accggcttcg aggacccgct gcacggggtg gacaccaccg
    14521 tgcccgcggg cgtcgacgcc ggctcgctgg ccgcggactg cgtggccctc gccgacgacg
    14581 ccctggtgag tgcccagcgg ctggccgagt ggaccacccg cgctcccgag ctggaggagg
    14641 aggtcgcgct cgccaacatc ggcctcgacc tcctcggcca ggcccgcctg ctgtacgcac
    14701 gcgcgggcca ggtcgacggc accgggcgcg gcgaggacgc gtacgcctac ttccgggacg
    14761 cggcggactt caggaacgta cggctggccg aactgccgaa cggggacttc gcgttctcgg
    14821 tcgtccggct gctggtgctg tccagttggc ggctcgcgca cttcgaggag ctgtcggcgc
    14881 atcccgaccc cgttctggcg gccgtcgccg cgaagggcgt caaggagctg acgtaccacc
    14941 ggcagtacgc ggccgagtgg gtcgtgcgcc tgggggacgg tacggacgag tcgcaccgcc
    15001 gtacgcgtag ggcgctggag caggtcgccc cgtacttcgg agagttgttc acggcctacg
    15061 acgtacggga cggggtcgtc gccgtcctgc ggcaggtcac cgaggcggcc gggctgccca
    15121 tgccggtgta ccggccgctg cccggggccg gccggagcgg ggagcacacc gggcatctgg
    15181 cgccgctgct ggcggagttg cagagcgtgg cccgtgcgca cccgggggcg acatggtgac
    15241 ggccatgacc gcatcgacgg atgcgcggcg cgcccggcgc gtcgccgagc aggtgccgga
    15301 ccccgaactg cccatgctca cgctggccga cctcggcgtc ctgcgtgcgg tcgaggtgac
    15361 cggggacggc accgtggtcg cgagcctgac gccgacctac tcgggctgcc ccgcgatggc
    15421 cgagatgcgc gcggacgtgg cggcacggct gcgcggcgcg gggtacgcgc gcgtggagat
    15481 ccgtacggtc ctcgacccgc cgtggaccag cgactggatc actccgcagg gccggcgcaa
    15541 actcaccgag cacgggatcg cgccaccggg agccgcaccc cggcacgccg cggggcctgt
    15601 gccgctcgtg ctggctccca cccgccgcac ggtggcgtgt ccgcgctgcg gtgcggcgga
    15661 caccgaggag acctcccgtt tcgccgccac gtcctgcaag gcgctgtggc gctgccgcgt
    15721 gtgccgcgag ccgttcgagt acgtcaagga gatctgatgg aaggcctgag ggaagagccg
    15781 gcggcgagtg cggcgagtgc ggcgagtccg gcgaaccggg ctgccgaggc cccggcagcc
    15841 gcccccgtgc ggccggtgcc cgcgcgcgtg cgccgccgcc cggccttcca cgctctgcgc
    15901 gtcgccgccg tgcagccgct ctgcgaggac gcggcggccg tgagcttcga gatcccggcg
    15961 gagctggcgg cggagttcgc cttcgcgccc gggcagtcgt tgacgctgcg gcgcgaggtc
    16021 gacggacggg acgagcggcg ctcgtactcg atctgttcgc cggccggttc ggcgccccgc
    16081 atcggagtgc gcgtggtgcc gggcggcctt ttctcggcgt ggctcgtgcg tgaggtgcgg
    16141 ccgggggaca cggttcaggt gatggccccc accggcacgt tcacgcccga cctcaccacg
    16201 cccggtcacc atgtgctggt cgcggccggc tccggtgtca cgccgatgct ctccatcgcc
    16261 gagtccgtcc tggccgccga cccgcgctcg acggtcaccc tcttctacgg caaccggcgc
    16321 acggacacgg tgatgttcgc cgacgaactg gcggacctga aggacctgta tccggcccgg
    16381 ttccagctcg cccacgtgct gtcccgcgag ccccgcgagg ccgaggtgct ctccggccgg
    16441 ctcgacgcgg accggctctc ggcactcgtc ggctcgctgg tcgacgtggc ggcggtggac
    16501 cactggtggc tgtgcgggcc gcacggcatg gtcctcgacg cccagcgggt cctgaccggc
    16561 ctcggcgtgc acggcgaccg cgtccaccgg gaactcttct acgccgacga cgagcccgta
    16621 cgagaggtgc gtcacgagga ggccgcgctg cgggggcccg tcagccaggt caccgtcacg
    16681 ctcgacggcc gctccaccac ctcggccctg gtcagggacc ggagcatcct cgaaggcgcc
    16741 cagcggaccc gccccgacct gcccttcgcc tgcaagggcg gcgtctgcgg cacctgccgc
    16801 gccctgatca ccgacggcaa ggccgacatg cgccgcaact tcgccctgga ggacgccgag
    16861 gtggccgcgg gctacgtcct gacctgccag tcataccctg tctccgagac gctgaccgtg
    16921 gattacgacg tctgacgggc actgacagcc ggtgacgggc ggtgctgagg ggcgctgacg
    16981 ggcggcgagg ggcgctgccg gggtacgggc ggggcacggg cggtggacgg atactcacca
    17041 cgggccactc accatgggca cttaactcat aagtcggcct tatgacgtca tagatccagc
    17101 ccggctactg acttaggctt gccttagttt aggctccccg tgagtactcc tgatcatcgc
    17161 tcgaagggaa cctgaacatg cctcgccccc tgcgggtagc catagtcgga gccggccccg
    17221 ccgggatcta cgccgccgac gcgctgttga agtccgcagt ggccgtcgag cccggtgtct
    17281 ccatcgacct cttcgagcgg atgccggccc ccttcggtct gatccgttac ggcgtcgccc
    17341 ccgaccaccc gcgcatcaag ggcatcatca cggccctgca ccaggtgctg gacaagccgc
    17401 agatccgcct cttcggcaac gtcgactacc cgggcgacat caacctggac gacctgcgcg
    17461 ccttctacga cgcggtgatc ttctccaccg gagcgacggc cgaccgggcc ctcgacatac
    17521 ccggtatcgg gctcgacggc tcccacggcg cggcggactt cgtctcctgg tacgacgggc
    17581 acccggacgt gccgcggacc tggccgctgg aggccgagaa ggtcgccgtc ctcggcgtcg
    17641 gcaacgtcgc gctcgacgtg gcgcgcatcc tcgcgaagac cgcggaggag ctgctgccga
    17701 ccgagatccc gccgaacgtc cacgaggggc tcaaggccaa caaggccgtg gaggtccacg
    17761 tcttcggccg ccgcggcccg gcgcaggcga agttcagccc gctggagctg cgggagcttg
    17821 accactcgcc gaacatcgag gtcatcgtcg accccgagga catcgactac gacgacggct
    17881 cgatcgcgac ccggcgcggc agcaagcagg ccgacatggt cgccaagacc ctggagaact
    17941 gggcgatccg cgacgtcggc gaccggcggc acaagctgtt cctgcacttc ttcgagtcgc
    18001 cgaccgagat cctcggcgag gacggcaagg tcgtcggcct gcgcacggag cgcacagcgc
    18061 tggacggcac cggcaacgtc aagggcaccg gcgagttcaa ggactgggac ctcggcgcgg
    18121 tctaccgtgc cgtcggctac ctgtccgaca agctgcccaa gctgccctgg gacgtcgact
    18181 cgggcaccgt cccggacaac gcgggccggg tgatcgagga gaccggcgag cacctgcggt
    18241 cgacgtacgt caccgggtgg atccggcgcg gtccggtggg cctcatcggc cacaccaagg
    18301 gcgacgccaa cgagacggtc gccagcctcc tcgacgacca ccggaacggc cgtctgcaga
    18361 cccccgtgtc gccggacccg gagtcggtgg acgcgttcct cgccgaccgg aacgtccgct
    18421 tcaccacgtg ggagggctgg taccgcctgg acgccgccga gaaggcgctg ggggagcccc
    18481 agggccgcga gcgggtgaag ctcgtggagc gcgaggacat gatcgaggca agcggcgcgt
    18541 agcttgcttt gtgaaaccga tcggtttacc gtttcgagca gacggaaacc gatcggtttc
    18601 cgcgtgatgc acgtgatgca cgtgatgcgt gtgatgcgtg tgatgcacgt gctgagtctc
    18661 ggagggtgtc atgaccgcaa tcgagggttc cgtcgtcctg gtgaccggcg gcggccgggg
    18721 catcggcaag gcgctggtgg aagggctctt cgaacggggg gcgaagaagg tgtacgccac
    18781 cgcccgcgac ccgcggacga tcacggacac ccgggccgtg ccgctggccc tggaggtcac
    18841 cgaccccgcg tccgtcgcgg cggcggccga gcaggccggc gacgtcaccg tcctgatcaa
    18901 caacgcgggc gtctccgtca acgcgtcctt cctcgacgcg ccggtcgccg acgtgcgccg
    18961 ggacttcgag acgaacttct acgggccgct gctcaccgcc cgggcgttcg tccccgtcat
    19021 cgagcgcaac ggcggcggcc acatcctcaa cgtccactcc gtgctgtcgt ggatcggcct
    19081 cgccggctcg tacagcgcct ccaaggccgc gctctggtcc cagacgaact ccctgcggct
    19141 ggacctggcc ccgcggggaa tcggtgtcac ggggctccat gtcggctacg tcgacacgga
    19201 catgaccgcg gcgatcgacg cgcccaagtc ctcgcccgtg gacgtggcgg cccaggcgct
    19261 cgacggcatc gagagcgggg ccttcgaggt gctcgccgac gacctgtccc gacgggtcaa
    19321 gtcgggactc gcggccgacc tgtcggtcct gtacccgcag ttggcggcct gaccgtcccg
    19381 gtataccgac cagtttccgg ctgtcgtccc ccggaggtag cctcgctccc atggccacca
    19441 gtacggacaa gacatccacg agggaccggc tgctcgacgc ggccatggag ctcttctacc
    19501 gcgacggcgt ctccctcggc gtcgaggcgc tgtgccgggc cgccggggtg tccaagcgct
    19561 cgatgtacca gctcttcgcg agcaaggacg aggtgctcgc ggcgagcctg gagcggcgcg
    19621 cgccggagta cgggcgcagg ctccgccccg gccccgacga cccccggtcg ccccgggagc
    19681 ggatcctgta cgtcttcgag cagttggagc aggcgtcgac ggaggacgac taccgggggt
    19741 gtccgtatct gtcggccatg gtcgagctca aggaccccga gcatccggcg agcgtcgtcg
    19801 ccctgcgggt caagggcacg ctgaccgagg cgttccgggt ggacgccgag cgcggtggcg
    19861 cccgcgaccc cgaactcctg gcccgccagc tcaccctgat cttcgacggc gccagcgccc
    19921 gagccggcgc aaaggcggaa accctccagg gcctgaccac caccacggca acggccttgc
    19981 tggacgcggc gggagtgaag tagcaggggc acccacccgg cgccccgtca ggggcgcggg
    20041 gaaaccgcgc gccaagccct gaccgaaggg gcggacggac gacggcgatg gccgggggtg
    20101 cttttcgggg gcgcggggaa ctgcgcaccc agcccccacc gaaggcgcgg acaaccaacc
    20161 aaccaaccga ccggcccgca ccgccgctca accccggccc gtacggccga tcgactccac
    20221 caacggcagc acccgttgcg gcacccgctc ccgcagcacc acctcggtcc gcgtacgaac
    20281 gacccccggc agactgatca gcgactggat cacatcctcc agatgaccgt tgtcccgcgc
    20341 gacgacccgc gtcagcagat ctcccccacc ggtgatcgag aacgcctcga tgatctccgg
    20401 cacggcggcc agcgcgtccc ccacgtcgtc gagattcccc tgggtgacct cgatgtgtac
    20461 gaacgcgagc accgggtggc ccagcgcggc aggggacagt gacggacccg taccggtgat
    20521 caccccgtcc cgctccagcc ggtcgagccg cgcctgcagc gtgccccggg cgacaccgag
    20581 gacgcgggcg tactcccgaa cgctcgtgct cggctgttcc aggagcagcc ggaggatacg
    20641 ggtgtcgagg tcgtccactg ccatggtccg ttggccttcc tgcggtctcg gctgatcatc
    20701 gccgactgta ccaatggctc agtggttcag aagcctgttg agccactgcc ctccccttgc
    20761 ctaacgtatg gtcatcaatg gcgtcgtgaa gcgccggacg gcaaggaagc cggccggacc
    20821 agcggcgcca ttcccatgcc ccggaagcca tgtccgggac ggtgtgtgaa acgggggcgg
    20881 gtttccgacg gtgaagaaga tgttcatggc tccggatccg ggcctggtac ggctgcggat
    20941 ctcactgcgg gccgtgctcg gcatcggtct cgcggtgacc gtgtcggagc tcgccgggct
    21001 ctcgctgccc gcctcgatca ccggagggct caccgcgctc ctcgcgctgt tcacggtcg
//
