LOCUS       NZ_AP023440            21835 bp    DNA     linear   CON 26-MAY-2024
DEFINITION  Streptomyces aurantiacus strain JCM 4677 chromosome.
ACCESSION   NZ_AP023440
VERSION     NZ_AP023440.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces aurantiacus
  ORGANISM  Streptomyces aurantiacus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 9428393)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye
            Genome Coverage                   :: 62X
            Sequencing Technology :: Illumina HiSeq X Ten; PacBio Sequel II
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014701115.1-RS_2024_05_26
            Annotation Date                   :: 05/26/2024 05:58:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,211
            CDSs (total)                      :: 8,122
            Genes (coding)                    :: 7,928
            CDSs (with protein)               :: 7,928
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 194
            CDSs (without protein)            :: 194
            Pseudo Genes (ambiguous residues) :: 0 of 194
            Pseudo Genes (frameshifted)       :: 69 of 194
            Pseudo Genes (incomplete)         :: 161 of 194
            Pseudo Genes (internal stop)      :: 17 of 194
            Pseudo Genes (multiple problems)  :: 48 of 194
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:48:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6670551
            Orig. end                         :: 6692386
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP023440.1.
            Genome sequencing and analysis were conducted under the Global
            Catalogue of Microorganisms (GCM) 10K type strain sequencing
            project (http://gctype.wdcm.org). The genomic data are also
            available at http://gctype.wdcm.org/sequencing/GCM10017557
            Annotated by DFAST v.1.2.7 (https://dfast.nig.ac.jp).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21835
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="CDPS"
                     /product="terpene"
                     /region_number="24"
                     /rules="CDPS"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21835
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="interleaved"
                     /product="CDPS"
                     /product="terpene"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..20801
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10000:10801](+)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10801
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     misc_feature    157..171
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     protocluster    798..21835
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10797:11835](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      10798..11835
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
     gene            850..3021
                     /locus_tag="IGS71_RS28495"
                     /old_locus_tag="GCM10017557_58190"
     CDS             850..3021
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326245.1"
                     /locus_tag="IGS71_RS28495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_58190"
                     /product="bifunctional glycosyltransferase 87/phosphatase
                     PAP2 family protein"
                     /protein_id="WP_190852803.1"
                     /transl_table=11
                     /translation="MANVEHGGRPGDGFGAAAPGTAKTRLDVVRVGLWLVAAVLAVRQV
                     AVVLSTPKGERLTDLETWVGPDGVLHVNGSLYDSTRFTGTPFSGLVLKPLTKAAEQALG
                     WGWTFGTLLLVVALGLVAARALPQPVSRRTSLLAAPVAISLLMLSLPVRNALYLGQTSI
                     IPVLLVLLGCFAVRGERASGVLIGLAAALQPTVLLFAPLLWFTGRRRAAGSTGLTFAAC
                     TALAWAAMPHDSYTYWVHHLAGVGLGRPADDLANQSLHGALLRLGVEGPLEIALFLALG
                     AAVAVLGLRRAVRYARDGQLLLAVAVTGCVAVAVAPTTWQHQLLWVLLAMAGRVGRKAG
                     DRYVWPVAVILVMTLPAKMMLPNMASLYPLRDNVVLIAALAAATAVPFLSRTSEYYRSP
                     VPTRYADPVPTRWRRVPLLPFLGRVLTRPNLLLELLLIRVGYSAYQQVRLAATGGTNSG
                     GRATAEHHGEQVHSIEKFFFIDIEHWVNHTVTNVRWLEDFFNFYYTSFHFVVPLSVLGV
                     LYARRPADYRWARAALGFATLFALVGFWLYPLAPPRLMPGLGFIDTVHGVQDFSKPDYG
                     TLTALTNQYAAMPSLHFGWSLWCGLVIAILAPRWWMKALGLLHPLFTVSAIVATGNHWV
                     LDAVGGAAVVGAGFGLTYLLQGPRPRPLAEPAGRTEKAGEVGEVGEVGDTARAEGAEGA
                     EGAEGAEGADAAGEVSISGTGPAKGRTPS"
     gene            complement(2975..4681)
                     /locus_tag="IGS71_RS28500"
                     /old_locus_tag="GCM10017557_58200"
     CDS             complement(2975..4681)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016644938.1"
                     /locus_tag="IGS71_RS28500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_58200"
                     /product="hypothetical protein"
                     /protein_id="WP_190852805.1"
                     /transl_table=11
                     /translation="MVSAELPLVGPEGAQPAHASQVSDQVSSQVSSQVSEVSRKRDLRP
                     FRVRHRVPLLATLPTVPLYVVWWLFLATGGGDLAAQEAWADFASRHSGSAYSLFWYGGM
                     HTANYSLISPYLMAALGVRTVTVTAGLLAAWLAAALVVRTGIHRPLGPALLASLALWCN
                     VASGRTTFALGIALGLAACVLLTGERRTAPAVAYAAFAAMASPVAGLFLVVAGAGYALV
                     RDRARAAALIVPPVLVVGATTLLFPFTGEQLMPAARIWPPVLIGVVVLTLAPRGWLVLR
                     WGAVVYAAGTVLTFLVPSPVGTNVERLAELFAPATLLAALLAVPAEAPLRRSNRTRRLA
                     LTMALVFSVGWVGKKTVDDLEVSTVVPAWAHHTTSVVEALDRLGADRTRVEVVPARNHR
                     EATALAPHVNLARGWNRQLDMERGRLFYDGTFSEKTYRAWLDRWAVGFVVLPSGKPDGF
                     AEDEARLVRNGTPWLEPVWRDPNWRVYRVRGAVPMVSAPATVERADSAEVVVRVPRPGA
                     VTVRVAFSPWLRAEGGCLAKEGEFTRLTVTEPGEYRISSGYGPSPGPSPRC"
     misc_feature    4755..4766
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.84"
                     /tool="antismash"
     gene            complement(4843..6087)
                     /locus_tag="IGS71_RS28505"
                     /old_locus_tag="GCM10017557_58210"
     CDS             complement(4843..6087)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298257.1"
                     /locus_tag="IGS71_RS28505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_58210"
                     /product="cytochrome P450"
                     /protein_id="WP_190852807.1"
                     /sec_met_domain="p450 (E-value: 7.6e-17, bitscore: 60.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPCPALPDGFDFTDPDVLHHRVPLPEFAELRRAEPVRWIPQPPNL
                     AGFGDEGYWAVTRHADVKYVSTHPELFSSTVNTAIIRFNEHIERDAIDAQRLILLNMDP
                     PEHTRVRQIVQRGFTPRAIRALEKNLHARAGRIVESALANAGPGGSFDFVTEVACELPL
                     QAIAELIGVPQEDRAKIFDWSNKMIAYDDPEYAITEEIGQEAATEILAYAMNMSADRKQ
                     CPAKDIATTLVAAENEGNLASDEFGFFVLMLAVAGNETTRNAITHGMHAFLTHPDQWDL
                     YKRERPATAAEEIVRWATPVVSFQRTATQDTELAGKQIRKGDRVGLFYSSANNDPEVFD
                     TPEVFDIDRDPNPHLGFGGGGPHFCLGKSLATLEIDLIFNAIADAMPGMRLVGDPRRLR
                     SAWINGVKELQVSAG"
     gene            6380..7549
                     /locus_tag="IGS71_RS28510"
                     /old_locus_tag="GCM10017557_58220"
     CDS             6380..7549
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124: acetyl-CoA acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003984210.1"
                     /locus_tag="IGS71_RS28510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_58220"
                     /product="steroid 3-ketoacyl-CoA thiolase"
                     /protein_id="WP_190852808.1"
                     /transl_table=11
                     /translation="MAAEPVIVEAVRTPIGKRGGALANLHPAYLLGETYRELLGRTGIH
                     ADCVEQIVGGTVTHAGEQSMNPARTAWLTMGLPYETAATTVDCQCGSSQQASHMVANMV
                     AAGVIDVGISCGVEAMSRVPLGSGSRHGPGKPFPDEWNVDLPNQFEAAERIARHRALTR
                     ENVDALGLVSQERAAIAWSEERFKRETFAVQVPTTEDEQRAGQGMWRLVDRDEGLRDTS
                     MEALAKLKPVMPTAVHTAGNSSQISDGASAIMWASKRMARALKLRPRARIVAQALVGSD
                     PHFHLDGPIDATKAVLGKAGMTLKDIDIVEINEAFASVVLSWTQTFDQDLEKVNVNGGA
                     IALGHPVGATGARLITTAVHELERRDKEFALITMCAGGALSTGTIIQRL"
     gene            complement(7640..8590)
                     /locus_tag="IGS71_RS28515"
                     /old_locus_tag="GCM10017557_58230"
     CDS             complement(7640..8590)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018539748.1"
                     /locus_tag="IGS71_RS28515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_58230"
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_190852810.1"
                     /transl_table=11
                     /translation="MTGVLVTGGTGKTGSALVDLLRGGGGVRGNGVRVRVRVASRNPSA
                     GDPDSVRFDWEDPATHPAALRGMDRVFLVPPVNVVDPMPLVGPFLAEAQRIGVRRLVLL
                     GSAIVLPNAPGPLELAERVRARPGWVVLRASGFMQNFLSPHPLGERIRQHGEIRTAAGA
                     GRLGWIDARDIAATASALLTHPDVDTGVDTGVGTSLDTGLDTGLDAGDRRDHLLTGPKA
                     LSYEDAAAIITARTGRPVRVRHIGSDELAASYRAAGLPAEFAAALAAVEDGIRAGREDL
                     VSTAVLDLTGRPPRPFAEFVQDHATEWTNTGLPDH"
     gene            complement(8587..8838)
                     /locus_tag="IGS71_RS28520"
                     /old_locus_tag="GCM10017557_58240"
     CDS             complement(8587..8838)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014059326.1"
                     /locus_tag="IGS71_RS28520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_58240"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_245702330.1"
                     /transl_table=11
                     /translation="MDAVADLWAPEGTAEFDTIVVEFTAHGRTVRTGEPYRLDYITVVT
                     ARDGLITRYRDYWSPPAAAAAAGDLPNLLDSLRPEATR"
     gene            9053..9892
                     /locus_tag="IGS71_RS28525"
                     /old_locus_tag="GCM10017557_58250"
     CDS             9053..9892
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018539750.1"
                     /locus_tag="IGS71_RS28525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_58250"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_190852812.1"
                     /transl_table=11
                     /translation="MSRAELADFLRRRREALHPDQLAATAVHPPGRRARRTPGLRREEV
                     AALAGVSNSYYERLEQARAPHPSPQVLAALAGALQLTAAERDYLARVAGQTPRGTDADR
                     PPVPADIRQFLDRLGPIPAYLADERLDILAWNSAAAELITDFGLLSGEERNVVRLAIRL
                     NGTLCSAPAGGDDEFARQSAAQLRAAAVHGPADRFLGELVNEFAAHSAAFAAGWRDHDV
                     RPIPTLRKHLRHPELGDLDLDCQTLLLPGTDLRLVMYTAQPGSSSAAALARLGTHGA"
     gene            10001..10801
                     /locus_tag="IGS71_RS28530"
                     /old_locus_tag="GCM10017557_58260"
     CDS             10001..10801
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014140974.1"
                     /locus_tag="IGS71_RS28530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_58260"
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /protein_id="WP_063792829.1"
                     /sec_met_domain="CDPS (E-value: 4.4e-70, bitscore: 234.7,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSKDVDAAEQEDPVPYGSSFTLEPYSENCRYVCGRREHVVFGVS
                     PGNSYFRVSRLADLLRWLCEEFRRVDVVIPDSALHHTYLALGYSPERAAKKVRSETNVL
                     RNRVLRGWELSGCPRDGNGLFLMSALAPRPSYQRLLAHVRSTLREDQDLRATAIRMTRE
                     ALIARGLTGEPTAEQLERGLQYLVAELPFFIGSADIFEVPSSVCFYHRPIPLADVIFDH
                     RSLLCPSPRQGYALISPTEPPAGETASAYGSGLHQRDAKEVNRT"
     gene            10798..11835
                     /locus_tag="IGS71_RS28535"
                     /old_locus_tag="GCM10017557_58270"
     CDS             10798..11835
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014151343.1"
                     /locus_tag="IGS71_RS28535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_58270"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_190852814.1"
                     /sec_met_domain="phytoene_synt (E-value: 3.3e-44, bitscore:
                     150.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.2e-24,
                     bitscore: 85.9, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQRELTAAGLTSPRVRQAYAACDAYLQRRNSAAFPAIRVLLPPA
                     KRPFWDAALAFCTFVDDLLDDPAWTVERRLARYSAYEQDLYRLMAGEERRPAPRPSDTG
                     EQLAYAFRHFVQTWRIPEHSVRRFMTTIRTDLEVTEYPRYADLTAYIEGVCVQGTLWGN
                     TLLEPQDEQSAARAAGCASFALQLTDYLQDLGEDLADGRLYLPLEELRTFGLSRADLEQ
                     AARDRRMTPPLRELVEYQVRRARGYFDEAADWWRLVDPSGRELPRQCVRLGQISLDRIE
                     RSEYDIFRVPRRVTLACAAASCAQFTAGYLRKTVAGRARGRRRTGELITPSVRPAARPA
                     AETDR"
     gene            11948..12820
                     /locus_tag="IGS71_RS28540"
                     /old_locus_tag="GCM10017557_58280"
     CDS             11948..12820
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (30-169). E-value: 1.3e-38. Score:
                     124.2. Matches aSDomain:
                     nrpspksdomains_IGS71_RS28540_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014627611.1"
                     /locus_tag="IGS71_RS28540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_58280"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_190852817.1"
                     /sec_met_domain="PCMT (E-value: 1.7e-06, bitscore: 26.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYQSGTRFQEDVQELYDRASERFAALYDDNLHFGYWDDDSDDTSL
                     AAATDRMTDLFIESLEVAPGRRVLDIGCGTGRPALRLARARGAEVVGISISGRETQRAN
                     ERSLSEGLERQVRFERADAMALPYGSASFDAAWALESMGHMSDRAQTLREIARVLRPGG
                     RLVIADGYRYEDRADAAGLALMDRLCAAFRMAPPPTLDGHADLLAAAGFTLVACRDLSP
                     HARRSMTRLIEIMEEKSGELAPLVGEEAFGLLMETLRTAAPSDLMGYVLLTARRHRPGE
                     TPEGSGPTR"
     aSDomain        12038..12454
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IGS71_RS28540_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.30E-38"
                     /label="IGS71_RS28540_oMT.1"
                     /locus_tag="IGS71_RS28540"
                     /protein_end="169"
                     /protein_start="30"
                     /score="124.2"
                     /tool="antismash"
                     /translation="LHFGYWDDDSDDTSLAAATDRMTDLFIESLEVAPGRRVLDIGCGT
                     GRPALRLARARGAEVVGISISGRETQRANERSLSEGLERQVRFERADAMALPYGSASFD
                     AAWALESMGHMSDRAQTLREIARVLRPGGRLVIAD"
     gene            complement(12886..13698)
                     /locus_tag="IGS71_RS28545"
                     /old_locus_tag="GCM10017557_58290"
     CDS             complement(12886..13698)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057281.1"
                     /locus_tag="IGS71_RS28545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_58290"
                     /product="acyl carrier protein"
                     /protein_id="WP_190852819.1"
                     /transl_table=11
                     /translation="MPSKTLTTRLAATAALLLAAGALATPSAAAKPADAAPGDAYVLTV
                     STNPASTDYDNRRVDVTGTVTKADGTPAPNIPVTLQEVVRFTTWNPWGDPIDPTYYEPR
                     DLGTPVSDADGEFTVPDVDIDHVGDSSLLNVQHDVQITALYDEDGDLNTPQDGHFADTT
                     VAADAKSSSVSYTVNRKKVKAGDVLVVQGKVTLPEGVEPEGTEVFLQTYWEGQYRVKTT
                     TEDDGFFVMSVRVRGYDDTFALRTAPRDLYVAGTERTLPITNTSLPRT"
     gene            complement(14056..14481)
                     /locus_tag="IGS71_RS28550"
                     /old_locus_tag="GCM10017557_58300"
     CDS             complement(14056..14481)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009188352.1"
                     /locus_tag="IGS71_RS28550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_58300"
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="WP_055519912.1"
                     /transl_table=11
                     /translation="MPFSTRVRRIASPKTALTGAAVAAATTGMVLAAGPAQAASPTVAT
                     SASAKATAQKMIHNDAQFKAFSKIVEHESGWNAAATNSSSGAYGLVQALPGSKMASAGA
                     DWKTNPKTQIKWGLDYMNSRYGSPTAAWSFWQANGWY"
     misc_feature    complement(14483..14494)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.32"
                     /tool="antismash"
     gene            complement(14779..15936)
                     /locus_tag="IGS71_RS28555"
                     /old_locus_tag="GCM10017557_58310"
     CDS             complement(14779..15936)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056530.1"
                     /locus_tag="IGS71_RS28555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_58310"
                     /product="hypothetical protein"
                     /protein_id="WP_213089210.1"
                     /transl_table=11
                     /translation="MADVADVADVADAADAAGMTAVAAAARRRQHTPDSESLVSLVRKH
                     HLAVRLATATAGAIIASTAVSAPAEAATPPLRDPGVVAHFDRPNGQVAESIVVEPDGSA
                     DVGLILSRQVAHVSPRGRVEVLATMPLPADGGVHTPTTGAASVTGIERTEDGTLYFLYS
                     AGDEHLTGLWKLRPGGTPVRIAALPAASFANGLARDDRTGDFYITDSTQGKVWRVRPNS
                     GTATVWADGPDLDPIDFFGANGVKVHNGAVWVSNIDHGTIVRIPLTGRGTLGKSGKPQI
                     RATGLDSVDDFAFTGRGDQLLAALNIPSKVVLITPGRPARTVLDRSDGLQNTTSVAVVK
                     DANANTDTDTDTDNNTDNNTTVYVTSGALTTGGDANLLTARLDRQ"
     gene            16019..16912
                     /locus_tag="IGS71_RS28560"
                     /old_locus_tag="GCM10017557_58320"
     CDS             16019..16912
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009320532.1"
                     /locus_tag="IGS71_RS28560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_58320"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_246596558.1"
                     /transl_table=11
                     /translation="MRDTEVMSRPENSLGEALRAWRDRLTTDDVGLPATGRRRTAGLRR
                     EEVASLAGVSVDYLLRLEQGRARCPSRHVIASIARALRLTGDEVCHLHLVAGLLPPVAG
                     QVPHEVPPSVDRLVSRWEDTAVGVFSASWTLLTWTQSWAALLGDPGTRPPRERNLIRAV
                     FAEPSAAGRSALLPFPADQNTAAFKAALVADLRLALAAYPGEKELAELVRESTQVSADF
                     REVWGTATLGSRLGGRTRIQHPLVGEIVLDSDVLKVPDHDMRIMTYTAEPGTPDAEKLD
                     LLRGTAVRTALPLSAG"
     gene            17013..17357
                     /locus_tag="IGS71_RS28565"
                     /old_locus_tag="GCM10017557_58330"
     CDS             17013..17357
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004938548.1"
                     /locus_tag="IGS71_RS28565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_58330"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_190852822.1"
                     /transl_table=11
                     /translation="MAETAGSGSDADSSDLIDVFKALGNPARLQIMQWLKNPETHFGEY
                     EPIADRQSVGVCVTHIQAKSGLAQSTVSSYMSTLERAGLVHPTRVGKWTHYRRDEKRLA
                     QVARAIDTTL"
     misc_feature    complement(17360..17373)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.69"
                     /tool="antismash"
     gene            17399..18091
                     /locus_tag="IGS71_RS28570"
                     /old_locus_tag="GCM10017557_58340"
     CDS             17399..18091
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003991239.1"
                     /locus_tag="IGS71_RS28570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_58340"
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="WP_190852824.1"
                     /transl_table=11
                     /translation="MSTFDAAPVALIVHAHPEPHSFSTAQMNTAAQALRDAGYRVDVLD
                     LYSDAWAPVLAREEFAPVEGHFKPQAEQQRAVEDGTLDAAVKAHLDRLLAADLLVLSFP
                     MWWFSLPSILKGWVDRVFVMGGVFGGDHGLFDDAALAGKRAMLLFTTGGSSESFRPGGA
                     FGSLDDFLFHIHRGMLEFVGFQVLDPVVTYGPARMTPQERTAALNAVGESVALVARAGT
                     PIRANTPV"
     gene            complement(18088..18945)
                     /locus_tag="IGS71_RS28575"
                     /old_locus_tag="GCM10017557_58350"
     CDS             complement(18088..18945)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015660779.1"
                     /locus_tag="IGS71_RS28575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_58350"
                     /product="ECF transporter S component"
                     /protein_id="WP_190852826.1"
                     /transl_table=11
                     /translation="MSPQPQPQPQPRTQPQPQARPIRLGPRSVAALVLVGVIGLAALTW
                     PFFSGPTSQVGAHAKDAPWLFAGLLVLLVGVVAATISESGLGPKAVAMLGVLAATGAAL
                     RPIGAGTAGIEPMFFLMVLSGRVLGPGFGFVLGAVTMFASALLTGGVGPWMPFQMLSMG
                     WFTMGAGLLPGPDRLRGRGELAMLAAYGFLAAFAYGTFMNLAGWPFMDALASNVAFDPA
                     DAVHTNLARFVAYCLATSLGWDLGRATVTVVLTLALGATVLKALRRATRRAAFETTVSF
                     EGPS"
     gene            complement(18942..20708)
                     /locus_tag="IGS71_RS28580"
                     /old_locus_tag="GCM10017557_58360"
     CDS             complement(18942..20708)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005478672.1"
                     /locus_tag="IGS71_RS28580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_58360"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_190852828.1"
                     /transl_table=11
                     /translation="MIRFEDVSVTYDGAAEPTVHGIELTVSEGELVLLVGPSGVGKSTL
                     LGAVNGLVPHFTGGTLRGRVTVAGRDTRTHKPRELADVVGTVGQDPLSHFVTDTVEDEL
                     AYGMESLGLAPDVMRRRVEETLDLLGLVELRDRPISTLSGGQQQRVAIGSVLTPHPEVL
                     VLDEPTSALDPAAAEEVLAVLQRLVHDLGTTVLMAEHRLERVVQYADRVALLPAPGAPL
                     TLGTPAEVMAVSPVYPPVVALGRLGGWSPLPLTVRDARRRAGPLRERLAEIATDGPHGD
                     PAAAPGPVRAAGPTPVAGAGARPSRRPGLFRRRTPVPPDASVSPAITPHPAVVEGLAVR
                     RGRTEVLHDVTLTVTPGETVALMGRNGAGKSTLLSALVGLVPPAAGSVRVGGLQPHRTA
                     PGELIRHVGLVPQEPRDLLYADTVAGECAAADSDAGAGPGTCRALVSELLPGIEDGTHP
                     RDLSEGQRLTLALAVVLTARPPLILLDEPTRGLDYAAKSRLVTLLRTLAAEGHAIVLAT
                     HDVELAAELSHRVVILADGEPVADGPTAEVVVASPSFAPQVTKILSPQKWLTVSQVRAA
                     LNTSEPEEGGRS"
     misc_feature    21639..21653
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.1"
                     /tool="antismash"
ORIGIN
        1 tcgggtcgtc gctgccggcg tcggtgacgg cgccgccgcg gacgacgttg tcgaggacga
       61 tcaggctgcc cgggcgggtg agtttcacgg cccattccac gtagcggggg ttgttcacct
      121 tgtccgcgtc gatgaagacc acgtcgaacg gggtggggtc ctcctcggcc agcgtccgca
      181 ggctgtccag ggccggcccc acccggacct cggtgagctt gtccaggccg gcgcgggcga
      241 ggttgtgccg ggccacctcg gcgtgccgtt cgctgtactc caggctgatg agccggccgt
      301 cctgcgggag ggcgcgggcc agccagatgg tgctgtagcc gccgagcgtg ccgatctcca
      361 ggatgcgggt cgcgccctgg atcacggcga ggaggtgcag cagcttgccc gtgttcgggg
      421 agacgttgat ctgtggcagc ccggcggcgt cgctgtcgcg cagcgcgtcg gtcagggcgg
      481 cgtccggcgg ggcaaggagg ccggtgaagt agtcgtccac gtcgtgccag agtcggggct
      541 cggtcatccg gtaggccttt cgtctctcta gttaggtgag ctaactagtt ccgttgccga
      601 atatagccgg ttaccggcag gtcgggtggt tgcattcccg tcacggcctc gcgtggcggc
      661 gttccgtggc gccatgtcgg cgtacaacac cttcatccgg acaaaagact gaaggacgtc
      721 aggtgaagag ggggttgcct gcgtcttccg acgggggtgg tgcgagcctc ttagagttcg
      781 aacaggaaac agacgcacga gacccatggg cacaacaggg gacgaacggg gcgggagggc
      841 cgacggcgcg tggcgaatgt ggagcacggt ggacgaccag gtgatggctt cggggcggcg
      901 gcgcccggga cggcgaagac acggctggat gtggtccgcg tgggcctctg gctggtcgcc
      961 gccgtcctcg cggtacggca ggtcgccgtc gtcctgagca caccgaaggg cgaacgcctg
     1021 acggatctgg agacctgggt cggacccgac ggcgtgctgc atgtgaacgg gtcgctctac
     1081 gactcgacgc ggttcacggg cacaccgttc agcggactcg tcctcaaacc cctcaccaag
     1141 gccgccgagc aggccctcgg ctggggctgg accttcggca cgctgctgct ggtggtcgcc
     1201 ctcggcctgg tcgccgcccg cgccctgccg cagcccgtca gccgccgtac ctcgctcctg
     1261 gccgcccccg tcgcgatcag cctgctgatg ctgtcgctgc ccgtgcgcaa cgcgctgtat
     1321 ctcggccaga ccagcatcat cccggtcctg ctggtgctcc tcggctgctt cgccgtgcgc
     1381 ggggaacggg cgagcggggt cctgatcggc ctcgcggcgg ccctgcagcc gaccgtcctg
     1441 ctgttcgcgc cgctcctgtg gttcaccggc cgccgccggg ccgccggctc caccgggctc
     1501 accttcgccg cgtgcaccgc gctcgcgtgg gcggcgatgc cgcacgactc gtacacgtac
     1561 tgggtgcacc acctggccgg ggtcggtctc ggccggcccg ccgacgacct cgccaaccag
     1621 tcgctgcacg gggcgctgct gcgcctcggc gtcgagggtc cgctggagat cgcgctcttc
     1681 ctggcgctcg gcgcggccgt cgccgtgctc ggcctgcgcc gcgccgtgcg ctacgcccgc
     1741 gacggacagc tgctgctcgc cgtcgcggtc accggctgcg tcgccgtcgc cgtggcgccg
     1801 accacctggc agcaccagct gctgtgggtg ctgctcgcga tggccggccg ggtcggcagg
     1861 aaagcgggcg accggtacgt gtggccggtc gccgtcatcc tcgtgatgac cctgccggcc
     1921 aagatgatgc tgccgaacat ggcgtcgctc tacccgctgc gcgacaacgt cgtactgatc
     1981 gccgccctcg ccgcggcgac cgcggtcccg ttcctgtccc gcacctccga gtactaccgc
     2041 tcgccggtcc cgacccggta cgcggacccg gtgcccacgc gctggcggcg ggtgcccctg
     2101 ctgccgttcc tgggccgggt cctcactcgg ccgaacctgc tcctggaact gctgctgatc
     2161 cgcgtcggat actccgcgta ccagcaggtc aggctcgcgg cgaccggtgg caccaactcc
     2221 gggggccggg ccaccgccga gcaccacggc gagcaggtcc actccatcga gaagttcttc
     2281 ttcatcgaca tcgagcactg ggtcaaccac acggtgacga acgtgaggtg gctggaagac
     2341 ttcttcaact tctactacac gtcgttccac ttcgtggtcc cgctgagcgt cctcggtgtt
     2401 ctgtacgccc gcaggcccgc cgactaccgc tgggcccgtg cggcgctcgg cttcgccacg
     2461 ctgttcgcgc tcgtcgggtt ctggctctac ccgctggccc cgccgcggct gatgcccggc
     2521 ctcggcttca ttgacaccgt gcacggcgtg caggacttct ccaagccgga ctacgggacg
     2581 ctgacggcgc tcaccaacca gtacgcggcg atgccctcgc tgcacttcgg ctggtcgctg
     2641 tggtgcgggc tcgtcatcgc gatcctcgcc cccaggtggt ggatgaaggc cctgggcctg
     2701 ctgcacccgc tgttcacggt ctccgcgatc gtggcgaccg gcaaccactg ggtgctggac
     2761 gcggtgggcg gcgcggccgt cgtcggcgcg ggcttcgggc tgacctacct gctccagggc
     2821 cccagacccc gaccgctcgc cgaaccggcc gggaggaccg agaaggccgg cgaggtcggc
     2881 gaggtcggcg aggtcggcga tactgcgcgg gccgaggggg ccgagggggc cgagggggcc
     2941 gagggggctg aaggggccga tgcggccgga gaggtcagca tctcggggac gggcccggcg
     3001 aagggccgta ccccgagctg atccggtact cgcccggctc ggtcaccgtc agccgcgtga
     3061 actcgccctc cttcgcgagg cagccgccct cggcgcgcag ccagggcgag aaggcgaccc
     3121 gcacggtcac cgcgccgggc cgtggcacgc gcaccacgac ctcggcgctg tcggcgcgct
     3181 cgaccgtggc gggcgccgac accatgggca ccgccccgcg cacccggtag acccgccagt
     3241 tcgggtcccg ccagaccggc tcaagccacg gggtgccgtt cctgaccagg cgcgcctcgt
     3301 cctccgcgaa gccgtccggc ttccccgagg gcagcacgac gaagccgacc gcccaccggt
     3361 ccagccaggc acggtacgtc ttctccgaga acgtcccgtc gtagaagagc cggccccgct
     3421 ccatgtccag ctgccggttc cagccgcgtg ccaggttcac gtgcggggcc agggcggtgg
     3481 cctcgcggtg gttgcgggcc gggaccacct cgacccgggt acggtcggcg ccgagccggt
     3541 cgagggcttc cacgacgctg gtggtgtggt gggcccaggc gggcacgacc gtcgacacct
     3601 ccagatcatc gacggtcttc ttaccgaccc accccacgga gaagaccagc gccatcgtca
     3661 acgcgagacg ccttgtccta ttgctgcgcc gcaggggcgc ctccgccggt accgcgagca
     3721 gcgccgccag caacgtggcg ggcgcgaaca gttccgcgag ccgttccacg ttcgtgccga
     3781 cgggggaggg gaccaggaac gtgaggaccg tcccggccgc gtacacgacg gcgccccagc
     3841 gcagcaccag ccagccgcgc ggcgccagcg tcagcacgac gacaccgatc agcaccggcg
     3901 gccagatccg ggcggcgggc atcagctgct cgccggtgaa cgggaagagc agtgtcgtcg
     3961 cgcccaccac caggaccggg ggcacgatca gcgcggcggc ccgcgcccgg tcccgtacga
     4021 gggcgtagcc ggcccccgcg acgaccagga acaggcccgc caccggactc gccatggccg
     4081 cgaacgccgc gtacgccacc gccggcgctg tccgccgctc cccggtcagc agcacacagg
     4141 ccgcgagccc gagggcgatg ccgagcgcga acgtcgtacg gcccgacgcg acgttgcacc
     4201 acagcgcgag cgacgcgagc agcgccgggc cgagggggcg gtggatgccc gtacggacga
     4261 cgagggccgc ggccagccag gcggcgagga gcccggccgt caccgtcacg gtccgcacgc
     4321 cgagggcggc catcagatag ggcgagatca ggctgtagtt ggcggtgtgc atcccgccgt
     4381 accagaagag gctgtacgcc gaaccgctgt gccgggacgc gaagtcggcc cacgcttcct
     4441 gtgcggccag atcgccgccg ccggtggcga ggaacagcca ccacaccacg tacagcggaa
     4501 cggtcggaag ggtggcgagg aggggcacac ggtgccggac ccgaaacggc cggaggtccc
     4561 gcttccggga gacctcggag acctgactgg agacctgact ggagacctga tcggagacct
     4621 gagaggcgtg ggcaggctgg gcaccctccg gtccgacgag gggcagttcg gctgagacca
     4681 cggctcgacg tttccgttcg aagtcttcga aggtgtgagt tggctgtgcc acctgtgaag
     4741 acgcgtaacg cgtcgaaaac gttgaccggc tgccgggggg agggaacccg cggaggcagg
     4801 ggcgcggcgg agggggagcg cccctgcctc tcgggcggcg ggtcagccgg cgctgacctg
     4861 cagctccttc acgccgttga tccaggcgga gcgcagccgg cgggggtctc cgaccaggcg
     4921 catgccgggc atcgcgtcgg cgatcgcgtt gaagatgagg tcgatctcca gggtggcgag
     4981 ggatttgccc aggcagaagt gcgggccgcc gccaccgaag cccaggtgcg ggttcgggtc
     5041 gcggtcgatg tcgaagacct ccggtgtgtc gaagacctcc gggtcgttgt tggcggagga
     5101 gtagaagagg ccgacgcggt cgcccttcct gatctgcttg ccggccagct cggtgtcctg
     5161 ggtcgccgtg cgctggaagg agacgacggg cgtggcccag cggacgatct cctcggcggc
     5221 ggtcgccggg cgctcccgct tgtagaggtc ccactggtcg gggtgggtga ggaaggcgtg
     5281 catgccgtgc gtgatggcgt tacgggtcgt ctcgttgccg gcgacggcca gcatcagcac
     5341 gaagaagccg aactcgtcgg aggcgaggtt gccctcgttc tcggcggcca ccagcgtggt
     5401 cgcgatgtcc ttggcggggc actgtttgcg gtcggccgac atgttcatcg cgtaggcgag
     5461 gatctcggtg gcggcctcct ggccgatctc ctcggtgatc gcgtactccg ggtcgtcgta
     5521 cgcgatcatc ttgttggacc agtcgaagat cttggcgcgg tcctcctgcg ggacgccgat
     5581 gagctccgct atcgcctgga ggggcagctc gcaggcgacc tcggtgacga agtcgaagga
     5641 gccgccgggg cccgcgttcg cgagcgcgct ctcgacgatc cggcccgcgc gcgcgtgcag
     5701 gttcttctcc agggcgcgga tggcacgcgg ggtgaagccg cgctggacga tctggcggac
     5761 ccgggtgtgc tcaggcgggt ccatgttgag caggatcagc cgctgggcgt cgatcgcgtc
     5821 gcgctcgatg tgctcgttga agcggatgat cgcggtgttg acggtggagg agaacaactc
     5881 ggggtgcgtg gacacgtact tgacgtcggc gtgccgggtg acggcccagt aaccctcgtc
     5941 cccgaagccg gcgagattgg gcggctgtgg gatccagcgg accggttcgg cccggcgcag
     6001 ttcggcgaac tccgggaggg gcacgcggtg gtgcagcaca tcgggatcgg tgaaatcgaa
     6061 cccgtcgggc agcgctggac agggcatcgg caactccagg tcgtacgacg atcgggttct
     6121 gacggcccat caggaaccgg gaattgtcgt gaaggtagta acgggttcta caagaggcaa
     6181 gaggcgcggc acctccaatc cgtgcgggat tcctccgtgc aggattcgtg cagatcacga
     6241 cttcgggagc tgcacgaccc ttgcggtggc ggacgccggg tcagcagact gcacacagaa
     6301 ctagaacgcg tactagttca gcgtggcggg tgggccggga cgcccgcgcc gcgcgggtga
     6361 cccgaggaga ggactcccca tggccgcgga acccgtgatc gtcgaagccg tacgcacccc
     6421 catcggcaag cgcggcggcg cgctcgccaa tctgcatccc gcctatctgc tgggcgagac
     6481 ctaccgtgaa ctcctcggcc gcaccggcat ccacgccgac tgcgtcgagc agatcgtcgg
     6541 cggcacggtg acgcacgccg gcgagcagtc catgaacccg gcgcgcacgg cctggctgac
     6601 gatggggctg ccgtacgaga cggcggcgac gactgtggac tgccagtgcg gttcctcgca
     6661 gcaggcctcg cacatggtcg ccaacatggt cgcggcgggc gtgatcgacg tcggcatctc
     6721 gtgtggtgtc gaggccatgt cgcgggtgcc gctgggctcc ggctccaggc acgggccggg
     6781 caagccgttc cccgacgagt ggaacgtgga cctgccgaac cagttcgagg cggcggagcg
     6841 gatcgcgcgc catcgcgcgc tgacccggga gaacgtcgac gcgctggggc tcgtctcgca
     6901 ggagcgggcg gcgatcgcct ggtccgagga gcgtttcaag cgcgagacgt tcgccgtgca
     6961 ggtgccgacg acggaggacg aacagcgtgc cgggcagggc atgtggcggc tcgtcgaccg
     7021 ggacgagggt ctgcgcgaca cctccatgga ggccctcgcg aagctgaagc cggtcatgcc
     7081 gacggcggtc cacacggcgg gcaactcgtc ccagatctcc gacggggcct ccgcgatcat
     7141 gtgggcgtcg aagcggatgg cgcgagcact gaagctccgc ccgcgcgccc ggatcgtcgc
     7201 ccaggcactg gtcggctccg acccgcactt ccacctcgac ggcccgatcg acgcgacgaa
     7261 ggcggtcctg gggaaggccg ggatgacctt gaaggacatc gacatcgtcg agatcaacga
     7321 ggcgttcgcg tcggtggtgc tgagctggac gcagaccttc gaccaggacc tggagaaggt
     7381 gaacgtgaac gggggcgcga tcgccctcgg gcatccggtg ggcgcgacgg gggcgcggct
     7441 catcaccacg gcggttcatg aactggagcg cagggacaag gagttcgcgc tgatcacgat
     7501 gtgcgcgggt ggggcgttgt cgacggggac gatcattcag cggctgtagg tggccggccg
     7561 cctcgaaggt gtgttgatcc cgtacggtcc tgcgtccgtg ggggtgtgca gagtcggcga
     7621 gtccgagcgc gggagccggt cagtgatcgg gcaagccggt attcgtccac tcggtcgcgt
     7681 ggtcctggac gaactcggcg aaggggcggg gtgggcggcc ggtcaggtcc agtaccgcgg
     7741 tgctgaccag gtcctcccgg ccggccctga tgccgtcctc cacggcggcg agtgcggcgg
     7801 cgaactcggc cggcaggccg gcggcccggt aggaggccgc cagttcgtcg gacccgatgt
     7861 gccgtacccg gaccggccgg ccggtgcgtg cggtgatgat cgccgccgcg tcttcgtagc
     7921 tcaacgcctt gggcccggtg agcaggtggt cacgccggtc gccggcatca agtcccgtat
     7981 cgagccccgt atcaaggctc gtaccgacac ccgtatcgac gcctgtatcg acgtcggggt
     8041 gggtcagcag ggcggaggcg gtggccgcga tgtcgcgtgc gtcgatccag cccagtcggc
     8101 cggcgccggc ggcggtgcgg atctcgccgt gctgccggat ccgttcgccc agtgggtgag
     8161 ggctcaggaa gttctgcatg aacccggacg cgcgcagcac gacccacccg ggcctggccc
     8221 gtacccgctc ggccagttcc agtgggccgg gagcgttcgg cagcacgatc gcggagccga
     8281 gcagcaccag gcggcgcacg ccgatgcgtt gtgcctccgc caggaacggg ccgaccagcg
     8341 gcatcgggtc cacgacgttc accggaggca ccagaaagac ccggtccatg ccccgcagcg
     8401 cggccgggtg ggtcgccggg tcctcccagt cgaaccggac cgagtcggga tcgccggcgg
     8461 acgggttgcg gctggccact cggacccgga cccggacccc gttccctcgc acacctcctc
     8521 cgccgcgcag caggtccacc agcgcgcttc cagtcttccc ggtgccgccg gtcaccagta
     8581 cgccggtcat cgggtggcct ccgggcgaag cgagtcgagc aggttcggca gatcgccggc
     8641 ggcggcagcg gcggccggcg gactccagta gtcccggtag cgggtgatca gcccgtcccg
     8701 ggcggttacc accgtgatgt agtccagccg gtacggctcg ccggtacgca ccgtgcgccc
     8761 gtgcgcggtg aactccacca cgatggtgtc gaactcggcg gtgccttccg gcgcccacag
     8821 gtcggcgacg gcatccatgt ccttggccgg cagcgactcc agcagccgac ggaagatctc
     8881 atcaggggta cgttcatcag gggtacgtga ggtacgtggc acggtgatcc tccggtgtcg
     8941 agcggtgtgt ccccaccagg ctgggccggg aatcccggcc gaggaacagt cggccgagcc
     9001 ccggaccacc agtccgtggc tgggccgggt ccccctgtgc caccctggcc gcgtgagcag
     9061 agccgaactg gcagacttcc tgcgccgccg acgggaagcg ctgcaccccg accagctggc
     9121 ggccaccgcc gtccacccgc cgggccggcg cgcgcggcgt acccccgggc tgcgacgcga
     9181 agaggtggcc gcgctggccg gggtgtcgaa cagctactac gaacgactgg aacaggcacg
     9241 cgcaccgcat ccgtccccgc aggtactggc cgcgctggcc ggcgcgctgc agctcaccgc
     9301 cgcggaacgc gactacctgg cacgggtggc ggggcagacc ccgcgcggca ccgacgccga
     9361 caggccgccc gtgcccgccg acatccgcca gttcctggac cggctcgggc cgatcccggc
     9421 ctacctggcc gacgagcgac tggacatcct cgcctggaac agcgcggcag ccgagctgat
     9481 caccgacttc gggctgctgt ccggcgagga acgcaacgtc gtccggctgg ccatccggct
     9541 gaacggcaca ctctgctcgg caccggccgg aggcgacgac gagttcgccc ggcagtccgc
     9601 cgcccagctg cgcgcggcgg ccgtccacgg ccccgccgac cggttcctcg gcgaactcgt
     9661 caacgagttc gcggcgcaca gtgccgcctt cgcggccggg tggcgcgacc acgacgtgcg
     9721 ccccatcccc accttgcgca agcacctgcg ccacccggag ctgggcgacc tggacctgga
     9781 ctgccagacc ttgctgctcc ccggcaccga cctgcggctg gtgatgtaca cggcgcagcc
     9841 gggcagctca agcgccgcgg cactcgcccg gctcgggacc cacggcgcct gaggcgaggg
     9901 cgcccgtgcc acccgaaggg cggaatggaa tcgctgggga tcatatgtgc ggttaccgtg
     9961 aatttgttct gagacgtgcg ggtaacgacg tctttttctt ttgtccagca aggacgtcga
    10021 cgcggcggaa caggaggatc ccgtgcccta cggctcttcc ttcaccctgg agccctacag
    10081 cgagaactgc cggtacgtct gtggcaggag agagcatgtg gtcttcggcg tcagcccagg
    10141 taacagctac ttccgggtga gcagactggc cgacctgctg cggtggctgt gcgaggaatt
    10201 ccgccgggtc gacgtggtga tcccggactc ggccctgcac cacacgtatc tggccctcgg
    10261 atactcgccg gagcgggcgg cgaagaaggt gcggagcgag acgaatgtcc tgcgcaaccg
    10321 cgttctgcgt ggctgggagt tgagcggctg tccgcgagac ggcaacgggc tcttcctcat
    10381 gtcggctctc gcgccccggc cgagttacca acggctgctg gcacacgtcc ggtccaccct
    10441 gcgcgaggac caggacctgc gcgccaccgc gatacggatg acacgggagg ctctgatcgc
    10501 ccgggggctc accggggagc ccactgccga gcagctggag cgcgggctcc agtacctggt
    10561 cgcggagctt ccgttcttca tcggctcggc ggacatcttc gaggtgccgt cgtcggtgtg
    10621 cttctatcac cggcccattc ccctggcgga cgtcatcttc gaccaccggt ccctgctgtg
    10681 tccgtcaccc cggcagggat acgcactgat ctccccgacg gaaccgcccg cgggcgagac
    10741 cgcctcggcc tacgggagcg gcctgcatca gcgagacgcg aaggaagtca accgcacatg
    10801 agccagcgag aactcaccgc ggcggggctg acgtcccccc gcgtgcgcca ggcctacgcc
    10861 gcctgcgacg cctacctgca acggcggaac tcagccgcgt tccccgcgat ccgtgtcctg
    10921 ctgccgccgg ccaaacggcc gttctgggac gccgccctgg cgttctgtac cttcgtcgac
    10981 gacctcttgg acgatccggc gtggaccgtg gagagaaggc tggcccgcta cagcgcgtac
    11041 gagcaggatc tgtaccgcct gatggcggga gaggagcggc ggccggcccc gcgtccgagc
    11101 gacacggggg aacaactggc ttacgccttc cggcacttcg ttcagacctg gcgcatcccc
    11161 gaacactccg tacgccggtt catgaccacc attcgcacgg atcttgaggt gaccgagtac
    11221 ccccgctacg cggacctgac ggcctacatc gagggcgtct gcgtccaggg caccctgtgg
    11281 ggcaacacgc tgctggagcc acaggacgag cagtcggcgg cccgggcggc aggctgcgcc
    11341 agcttcgccc tccagctcac cgactacctt caggacctgg gagaagacct ggcggacggg
    11401 cggctctacc ttccgctgga ggagctgaga acgttcggcc tcagccgcgc ggatctggaa
    11461 caggcggccc gtgacaggcg gatgacccct ccgctgcggg aactggtgga gtaccaggtc
    11521 cgccgagcac ggggttactt cgacgaggcg gccgactggt ggcggctcgt ggacccgtcc
    11581 ggacgcgagc tgccccgtca gtgcgtgcgg ctggggcaga tcagcctgga ccggatcgag
    11641 cgctcggagt acgacatctt ccgggtaccg cggcgggtga cgctcgcctg cgccgccgcg
    11701 tcctgcgcgc aattcaccgc tggatacctg cgcaagaccg tcgccggccg ggcccggggc
    11761 cgcaggcgaa caggagagct catcaccccg agtgtccggc ctgcggcgcg ccccgccgcg
    11821 gagacggacc ggtgacggcc accggcgccg tcaccgcacc ggccggcacc gcgcgacacg
    11881 gcctcgggcc ccgtccacag gacactgtcc cctcggtcaa ctcggtcaac tcggtttgag
    11941 gaaagccatg tatcagtccg ggacccgttt ccaggaagac gtacaggagc tgtacgacag
    12001 ggcgtcggag aggttcgccg ccctgtacga cgacaatctg cacttcgggt actgggacga
    12061 cgactccgac gacacctccc tcgccgccgc caccgaccgg atgacggacc tgttcatcga
    12121 gtccctcgaa gtcgctcccg gccgacgggt gctggacatc ggatgcggga ccggcaggcc
    12181 agccctgcgc ctggcccggg cgcgcggcgc ggaggtcgtc ggcatctcca tcagcggccg
    12241 ggagacgcag cgcgccaacg agcgcagcct gagcgaagga ctggagcggc aggtgcgctt
    12301 cgagcgggcc gacgcgatgg cgctgccgta cgggagcgcg tccttcgacg ccgcgtgggc
    12361 gctggagtcc atgggccaca tgtcggaccg cgcgcagacg ctgcgcgaga tcgcccgggt
    12421 cctgcggccc ggcggacggc tggtgatcgc cgacggctac cgctacgagg accgcgccga
    12481 cgccgccggc ctcgcgctca tggaccgcct gtgcgcggcc ttccggatgg ctcccccgcc
    12541 caccctggac gggcatgccg acctgctggc cgccgccggg ttcaccctcg tggcgtgcag
    12601 ggacctctcc ccgcacgccc ggcgctcgat gacccgcctg atcgagatca tggaggagaa
    12661 gtccggggag ttggcaccgc tcgtggggga ggaggccttc ggccttctga tggagacctt
    12721 gaggacggcc gcgccctccg acctcatggg atacgtcctg ctgaccgccc ggcgtcaccg
    12781 gcccggggaa acacccgagg gcagcggtcc gacccggtga acgcgggccg gtcggtcgaa
    12841 gcaccgacgc atgaggacaa agggccggtc ccggttccct cggggctacg tgcgaggcag
    12901 tgaggtgttg gtgatcggga gcgtccgttc cgtgccggcc acgtagaggt ccctcggggc
    12961 cgtgcgcagc gcgaacgtgt cgtcgtagcc ccggacacgc acggacatca cgaagaagcc
    13021 gtcgtcctcg gtggtcgtct tcacgcggta ctggccctcc cagtaggtct gcaggaagac
    13081 ctcggtgccc tcgggctcga ccccctcggg gagggtgacc ttgccctgga cgacgaggac
    13141 gtcgcccgcc ttcacctttt tcctgttgac cgtgtaactg accgagctgg acttggcgtc
    13201 ggcggccacg gtggtgtccg cgaagtggcc gtcctgcggg gtgttgaggt cgccgtcctc
    13261 gtcgtacagg gccgtgatct gtacgtcgtg ctggacgttg agcaggctgc tgtcgcccac
    13321 gtggtcgatg tcgacgtccg ggacggtgaa ctcgccgtcg gcgtcggaga ccggagtgcc
    13381 caggtcgcgc ggctcgtagt aggtggggtc gatcgggtcg ccccacgggt tccaggtggt
    13441 gaagcggacg acctcctgga gggtgacggg gatgttcggt gccggggtgc cgtcggcctt
    13501 ggtcacggtg ccggtgacgt cgacgcggcg gttgtcgtag tcggtggagg ccgggttggt
    13561 gctcacggtc agcacgtagg cgtcgccggg agcggcgtcc gcgggcttcg ccgctgcgga
    13621 gggtgtggcc agggcgcctg cggcgagcag gagcgcggcg gtggcggcaa gccgcgtcgt
    13681 cagggtttta ctgggcacgg gtcaactcca agttcggtcg ggactgcagg agtcgcgccg
    13741 ggcggcaccg gttccgccgc ggcacacgtg tctgacacat caggtgcgac cggtggggtc
    13801 gggcggaagt tgtacctgtg cgggccccgt tacgcggctg tggcggggga ccgttatggg
    13861 cgggtttcgg gttcacctgg gcgttgggcg tgggccgccc tccgttaccc gacacaatcg
    13921 ttgcccctgc ccctgcccgc gacaagcgaa ggcggcggcc caggggatca ggggccgccg
    13981 ccttcgcgta cgggggagtc gtgagcggtg ccggtgcctc gtgggcgccg tccggtcggc
    14041 tcggtgccgg tcggctcagt accagccgtt cgcctgccag aagctccagg ccgccgtcgg
    14101 gctgccgtag cgggagttca tgtagtcgag gccccacttg atctgggtct tcgggttcgt
    14161 cttccagtcg gcacccgcgg aggccatctt cgagcccggc agggcctgga ccaggccgta
    14221 ggcgccggag gaggagttcg tggcggcggc gttccagccg ctctcgtgct cgacgatctt
    14281 cgagaacgcc ttgaactggg cgtcgttgtg gatcatcttc tgcgcggtcg ccttggccga
    14341 ggcggacgtg gccaccgtgg gggaagcggc ctgggcggga cccgccgcga gcaccatgcc
    14401 ggtcgtggcg gcggccacgg cggcaccggt gagggccgtc ttcggggagg cgatgcggcg
    14461 gacgcgggtg gagaagggca cggagaacct tttctacggg gacgggggcg gccgctcgta
    14521 cgccctgacg tccagccctg gcatgcggtg gcgccgagtc ccggacgggt acgtcggcgc
    14581 cttgcgactc ctccagagaa acaggcccgc acggtgtccg caatgccccc ttttgctagt
    14641 tgaggccgta ctcgccgcac aaggtcccgc tgtggcgtgg gtctcaatcc gcaggtcaga
    14701 ggccgtgggt ggggtgggca tgacaaggga atcggctacg aaggtgcctc gtaggggacc
    14761 aaggtcctgt gggccgcttc actgccggtc gaggcgtgcc gtcaggagat tcgcgtcgcc
    14821 gcctgtggtg agtgcgccgc tggtcacgta gacggtggtg ttgttatcgg tgttgttgtc
    14881 ggtgtcggtg tcggtgtcgg tgttggcgtt ggcgtccttt acgacggcga ctgatgtggt
    14941 gttctgcagg ccgtcgctcc ggtcgaggac cgtgcgtgcc ggcctgcccg gggtgatgag
    15001 caccaccttg ctggggatgt tcagggcggc cagcagttgg tcgccccggc ccgtgaaggc
    15061 gaagtcgtcg acgctgtcca gtcccgtggc cctgatctga ggcttcccgg acttcccgag
    15121 cgttcccctg cccgtcagcg ggatgcgcac gatcgttccg tggtcgatgt tggacaccca
    15181 tacggcgccg ttgtggacct tcacgccgtt ggcaccgaag aagtcgatcg ggtcgaggtc
    15241 gggcccgtcg gcccagaccg tcgccgtgcc ggagttcggg cggacccgcc acacctttcc
    15301 ctgtgtggag tcggtgatgt agaagtcccc ggtgcggtcg tcccgcgcga gcccgttggc
    15361 gaagctcgcc gccggcaggg ccgcgatacg taccggggtg ccgccggggc gtagcttcca
    15421 caggccggtg aggtgctcgt cgcccgcgga gtagaggaag tagagcgtgc cgtcctcggt
    15481 ccgttcgatt ccggtgacgg aggcggcgcc ggtggtcggg gtgtgcacgc ctccgtccgc
    15541 cgggagcggc atggtggcca gcacctcgac gcgtccgcgg ggggagacgt gggccacctg
    15601 gcgggacagg atcaggccga cgtcggccga accgtcgggc tccacgacga tgctctccgc
    15661 gacctgcccg ttcggccggt cgaagtgcgc cacgacgccg gggtcccgga ggggcggcgt
    15721 ggccgcttcg gctggtgccg ataccgcggt ggaggcgatg atcgcccccg cggtggctgt
    15781 cgccaggcgg acggcgaggt ggtgcttgcg cacgagtgac acgagtgact ccgaatctgg
    15841 ggtgtgttgc cggcggcggg ccgcggcggc cacggcagtc atgccggccg cgtcggccgc
    15901 gtcggccacg tcggccacgt cggccacgtc ggccacggaa cagcgtcggt ctctgcgtgc
    15961 cgctcagcca gtaccctgct caaccctgga atcgcagtac cacgctaacg atcgcccggt
    16021 gcgcgacact gaagtcatga gccggccgga gaactccctg ggtgaggcgc tgcgtgcctg
    16081 gcgcgaccgc ctcacgacgg acgacgtcgg cctgccggcc accggacgcc ggcggacggc
    16141 cggactgcgt cgtgaggaag tcgcgtcact tgccggagtc tccgtcgact acctcctgcg
    16201 cctggagcag ggccgcgccc ggtgcccgtc gcgccacgtc atcgcctcga tcgcccgcgc
    16261 gctgcgcctg accggcgacg aggtgtgcca tctgcatctc gtcgcggggc tgctgccgcc
    16321 ggtggcgggc caggttccgc atgaggtgcc gccgagtgtc gaccggctcg tcagccggtg
    16381 ggaggacacg gccgtggggg tgttctcggc ctcctggacc ctgctgacct ggacgcagtc
    16441 ctgggcggcc ttgctgggtg acccgggcac ccggccaccg cgggaacgca acctgatacg
    16501 agcggtcttc gccgagccct cggcggccgg ccgctccgcc ctcctcccct tccccgccga
    16561 ccagaacacc gccgccttca aggcggccct cgtcgccgat ctgcggctcg ccctcgccgc
    16621 gtacccgggg gagaaggaac tcgccgaact ggtccgggag agcacacaag tcagtgcgga
    16681 cttccgggag gtgtggggca ccgcgacgct cggttcgcgc ctcggcggcc ggacgcggat
    16741 ccagcaccct ctcgtcggag agatcgtgct ggacagcgac gtactgaagg tgccggacca
    16801 cgacatgcgg atcatgacgt acaccgcgga acccggcaca ccggacgccg agaagctcga
    16861 ccttctgcgg ggtaccgccg tccgcaccgc actgccgctt tccgccggat gaggtgtgtg
    16921 ccaggtccca gcggcctcgg tccggccggc cgctgcgaac cggataccga gatatcgtgg
    16981 tgtgtcgaag tgtctggtgg gaggggtgac tcatggccga aacggcgggc tcgggctcgg
    17041 atgcggattc gagtgatctc atcgacgtgt tcaaggccct tggcaacccc gcccgtttgc
    17101 agatcatgca gtggctgaag aatcccgaaa cgcacttcgg cgagtacgag ccgatcgcgg
    17161 accggcagtc cgtcggtgtg tgcgtcacgc acatccaggc gaagtcggga ctcgcccagt
    17221 caaccgtctc cagctacatg agcacgctcg aacgggcggg cctcgtgcat cccacccggg
    17281 tgggcaagtg gacccactat cggcgcgatg agaaacggct ggcgcaggtg gcgcgagcga
    17341 tcgacaccac tctctgattt ttgattgacg aatcgcaata tgtcgatatg atctcgtcat
    17401 gtcgaccttc gatgctgccc ccgtcgcctt gatcgtgcac gctcaccctg agccccactc
    17461 gttcagtacg gctcagatga acactgcggc tcaggccctg cgcgatgccg ggtaccgggt
    17521 cgacgtcctc gacctctact ccgacgcatg ggccccggtc ctcgcccgcg aggagttcgc
    17581 accggtggaa ggtcacttca agccgcaggc cgagcagcag cgcgcggtcg aggacgggac
    17641 gctcgacgcg gccgtcaagg cccatctcga tcggctgctc gccgctgacc tgctcgtgct
    17701 gtcgttcccg atgtggtggt tctcgctgcc gtccatcctc aagggatggg tggaccgggt
    17761 cttcgtgatg ggcggggtct tcggcgggga ccacggactc ttcgacgacg cggcgctcgc
    17821 ggggaagcgg gcgatgctgc tgttcacgac cggcgggtcc agcgagtcgt tccggcccgg
    17881 tggcgccttc ggctcgctgg acgacttcct gttccatatc caccggggga tgctggagtt
    17941 cgtcggcttc caggtactcg accccgtggt cacctatgga cctgcccgca tgactcccca
    18001 ggaacgcacg gcggcgctga acgcggtcgg agagtctgtc gcgctcgtcg cgagggcagg
    18061 cacgcccatc agggcgaaca cgcccgttta ggaagggcct tcgaagctga ctgtcgtctc
    18121 gaaagccgcc ctccgtgtgg cccggcggag cgccttgagg accgtcgccc ccagcgcgag
    18181 ggtcaggacg accgtcaccg tggcccggcc caggtcccag ccgagcgacg tggccaggca
    18241 gtacgcgacg aagcgggcca gattggtgtg cacggcgtcg gccgggtcga aggcgacgtt
    18301 cgaggccagc gcgtccatga agggccagcc ggccaggttc atgaacgtgc cgtacgcgaa
    18361 ggccgccagg aagccgtacg cggcgagcat cgccaattca cccctgccac gcagccggtc
    18421 gggccccggc agcagccccg ctcccatcgt gaaccagccc atcgagagca tctggaacgg
    18481 catccagggc ccgaccccgc ccgtgagcag cgccgacgcg aacatcgtga ccgcccccag
    18541 cacaaagccg aaccccggcc cgagcacccg cccgctcagc accatcagga agaacatcgg
    18601 ctcgatccct gccgtaccgg ccccgatcgg ccgcaacgcg gccccggtcg cggcgagcac
    18661 cccgagcatc gccacggcct tgggcccgag acccgactcg gagatcgtcg ccgcgacgac
    18721 cccgaccagc agcacgagca acccggcgaa cagccagggc gcgtccttcg cgtgggcgcc
    18781 cacctgcgag gtcggcccgc tgaagaaggg ccaggtcagc gcggcgagac cgatgacacc
    18841 caccaggacg agggcggcga cggagcgggg gcccaggcgg atggggcggg cttggggctg
    18901 gggttgagtg cggggctgtg gttgaggctg tggctgaggg ctcatgagcg tcctccctcc
    18961 tccggctcgg acgtgttcag cgccgcgcgc acctgggaga ccgtcagcca cttctgcggg
    19021 gagaggatct tggtgacctg cggggcgaac gacggggagg cgacgaccac ctcggccgtc
    19081 gggccgtcgg ccaccggttc gccgtcggcg aggatgacca cccggtggga gagttcggcg
    19141 gccaactcca cgtcatgggt ggccagaacg atggcatggc cctcggcggc gagggtccgc
    19201 aggagcgtga ccaggcggga cttggccgcg tagtcgaggc cgcgggtcgg ctcgtcgagg
    19261 aggatcagcg gcggccgggc cgtcagtacg acggccagcg ccagggtgag ccgctgcccc
    19321 tccgagaggt cccgcggatg cgtaccgtcc tcgatgcccg gaagcagctc ggacaccagc
    19381 gcccggcagg tgcccggccc cgcccccgcg tcggagtccg ccgccgcgca ctcaccggcc
    19441 accgtgtccg cgtacagcag gtcccggggt tcctgcggta cgaggcccac gtggcggatg
    19501 agttcaccgg gcgccgtgcg gtggggctgg agcccgccca cgcgtaccga acccgccgcg
    19561 ggagggacta ggccgacgag ggcggagagc agcgtcgact tgccggcgcc gttgcggccc
    19621 atgagtgcga cggtctcgcc gggggtgacg gtcagggtga cgtcgtggag tacctcggtg
    19681 cggccacggc ggaccgcgag tccctcgacc accgccgggt gcggggtgat ggcgggggac
    19741 acagaggcgt cggggggcac gggggtgcgc ctgcggaaga gtcctgggcg gcgggagggc
    19801 ctcgcgccgg ctccggccac cggcgtcggg cctgccgcgc gtacgggtcc cggcgccgcg
    19861 gccgggtcgc cgtgcgggcc gtcggtcgcg atttccgcca ggcgttcccg tagtggtccc
    19921 gccctgcggc gggcgtcccg gaccgtcagt ggcaggggtg accagccgcc gagcctgccc
    19981 agggccacca ccggtgggta caccggtgac acggccatga cctcggcggg cgtgcccagc
    20041 gtcaacgggg cgcccggggc cgggagaagg gcgacccggt cggcgtactg cacgacgcgt
    20101 tccaggcggt gttcggccat gaggaccgtc gtgccgaggt cgtggacgag gcgttggagg
    20161 accgcgagga cctcctcggc ggcggccggg tcgagggccg aggtcggctc gtcgaggacc
    20221 aggacctcgg ggtgcggggt gaggaccgag ccgatcgcca cccgctgctg ctgtccgccg
    20281 gagagcgtgg agatggggcg gtcgcgcagt tcgacgagtc cgagcaggtc aagggtctcc
    20341 tcgacgcggc ggcgcatcac gtccggcgcc aggcccaacg actccatccc gtaggcgagt
    20401 tcgtcctcga ccgtgtccgt gacgaagtgc gacagcgggt cctggcccac cgtgccgacc
    20461 acgtcggcga gttcgcgggg cttgtgtgtg cgcgtgtcgc ggcccgccac cgtcacgcgc
    20521 ccgcgcaggg tgccgcccgt gaagtgcggg accagcccgt tcaccgcacc gagaagcgtc
    20581 gacttgccga cgcccgaggg gccgaccagc agtaccaact cgccctcgga gacggtgagt
    20641 tcgatgccgt ggacagtggg ctccgccgcc ccgtcgtacg tcacggagac atcctcgaag
    20701 cggatcacga agactccttg ccgaagcccc tgggggcggg ggagggggcg accagggccg
    20761 gggtcagacc gaggaggatc gccgccgcgg gccacagtgg aagcgtcggc gccgtcagcg
    20821 ggacgacatc ggggtgcagg gccgcgtagg cgtacgggtc gtgggaggcg tacaggatca
    20881 gcagcgccgc gacggccgcg ccggacgcgg cgacgagcca cgcgcggacg ccccacgcgt
    20941 ccggccggta ccgggtgcgc agcgagcggc ggccaccgag ccacaggtcg ccgagggcag
    21001 cgccgagtcc ggcgagcagc acgggcaggc cgtagctgcc gccctccgcg gtgagcaggc
    21061 cgtacgttcc cgcgcagacc ccgacaagac cgccgagggt gagcgcggcg gtggtgcggt
    21121 gcacggccgg cgccacctcg gcggtgcggc cgtatccgcg cgcgtccatc gccgccgcga
    21181 gcgccaccga acgctccaac gcgccctcca ggaccggcag tccgacctgg agcaggccgc
    21241 gtacgccgct gtcgggccgg ccgcgcaggc gccgggccgc gcgcagccgc tggacgtccg
    21301 cgatcaggtt cggggcgaag gtgagcgcga ccactacggc gacgcccgcc tcgtacaggg
    21361 cgcccgggag ggatttgagg aggcgggccg ggttggcgag ggcgttcgcg gcgcccacgc
    21421 agatgaggag cgtggcgagt ttcaggccgt cgtagagggc gaagaccagg ccctcggccg
    21481 tgacacggcc accgacgcgg atgccttcgg cccaggcggg gagcgggagt tcggggaggg
    21541 tgacgagggt gtgcgtaccc gggatgggtg agccgaggag gacggcgaag gccagccgga
    21601 tgccgagcac ggcgagcgcg agcttgacga aggcgccgta ggagcgcgcc cagggggcct
    21661 ccgtccggcg cgccgccacc acgtaaccgg cgacgccgac gaggagtccg aggaggagcg
    21721 ggttcgtggt gcgggacgcg gcggtgccca ggcccagggc ccagatccac caggcaccgg
    21781 ggtggacggc gttggtacgg gtcgcgcgcg gggcacggag cttccgcagg attct
//
