LOCUS       NZ_AP023440            22526 bp    DNA     linear   CON 26-MAY-2024
DEFINITION  Streptomyces aurantiacus strain JCM 4677 chromosome.
ACCESSION   NZ_AP023440
VERSION     NZ_AP023440.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces aurantiacus
  ORGANISM  Streptomyces aurantiacus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 9428393)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye
            Genome Coverage                   :: 62X
            Sequencing Technology :: Illumina HiSeq X Ten; PacBio Sequel II
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014701115.1-RS_2024_05_26
            Annotation Date                   :: 05/26/2024 05:58:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,211
            CDSs (total)                      :: 8,122
            Genes (coding)                    :: 7,928
            CDSs (with protein)               :: 7,928
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 194
            CDSs (without protein)            :: 194
            Pseudo Genes (ambiguous residues) :: 0 of 194
            Pseudo Genes (frameshifted)       :: 69 of 194
            Pseudo Genes (incomplete)         :: 161 of 194
            Pseudo Genes (internal stop)      :: 17 of 194
            Pseudo Genes (multiple problems)  :: 48 of 194
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:48:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6207375
            Orig. end                         :: 6229901
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP023440.1.
            Genome sequencing and analysis were conducted under the Global
            Catalogue of Microorganisms (GCM) 10K type strain sequencing
            project (http://gctype.wdcm.org). The genomic data are also
            available at http://gctype.wdcm.org/sequencing/GCM10017557
            Annotated by DFAST v.1.2.7 (https://dfast.nig.ac.jp).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22526
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="23"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22526
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22526
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12526](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12526)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(1483..1496)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.28"
                     /tool="antismash"
     gene            complement(2468..3358)
                     /locus_tag="IGS71_RS26500"
                     /old_locus_tag="GCM10017557_54180"
     CDS             complement(2468..3358)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006142885.1"
                     /locus_tag="IGS71_RS26500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_54180"
                     /product="NmrA/HSCARG family protein"
                     /protein_id="WP_190852462.1"
                     /transl_table=11
                     /translation="MSTQTTGTIAVFGATGQQGGAVVDALLDHKARVRALVRDPQSDRA
                     QALAARGVEPAAVRADDPASLAAALATVEAFYFMTPEANSLEEVEAEIRIGTALVDAAV
                     EAGVPHVVFNSVFGADRESGVPHHDSKHWIEEHLRKSGLRASMVRATAFMENFASVMAP
                     SLEHGEIVLRLPLPEDVPLKMISVRDIGRVAAALLLGTAEAPGGAVELVGDDLTGPQIA
                     AVFGAHAGLPARYEALPLSVLPTDLDRVMFREFAQAAEYPSDPAVVRSIEPATLDLAEW
                     IRATGWTAPTDVAGS"
     gene            complement(3451..3891)
                     /locus_tag="IGS71_RS26505"
                     /old_locus_tag="GCM10017557_54190"
     CDS             complement(3451..3891)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031892.1"
                     /locus_tag="IGS71_RS26505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_54190"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_190852464.1"
                     /transl_table=11
                     /translation="MDYGDKLFWLSVVIQRKYAQICAGFDLTPSQATLICAVRNEPRQM
                     ADLAASLGMTKNALSQLVDRTARRELVGRASSAQDRRVVMLSATPTGKVLAEAIYAEIA
                     KRLPEIARNLDADDQRDFERVATAIVDTSDLSSPTTDPPVTP"
     gene            complement(3962..4843)
                     /locus_tag="IGS71_RS26510"
                     /old_locus_tag="GCM10017557_54200"
     CDS             complement(3962..4843)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016641726.1"
                     /locus_tag="IGS71_RS26510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_54200"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_190852466.1"
                     /transl_table=11
                     /translation="MDVLSDAIGTMRVGRPSLSLEAADPSEEREVQTFEGARFYVGTTG
                     RIRVTAPGEAVITLLPGDAVLLPHGTAHTLVSATDSTAQFLSGAYRLERARPHPLFQDL
                     ADVVSLPARPDRYPGLQASIDLLLSELGEQMHGRDLVLPALLEVLLVHLIRACLIERAG
                     LQATGWCVALDDEVIARSLRAVHERPADPWTVESLGAHAGLSRAAFARRFTALVGQPPL
                     TYLTWWRLTTAARLLQTTDVPLFTVAQRSGYGSVYAFANAFKREYGTSAGRYRQQHRTD
                     HHAGLAEVCISW"
     gene            complement(4866..5777)
                     /locus_tag="IGS71_RS26515"
                     /old_locus_tag="GCM10017557_54210"
     CDS             complement(4866..5777)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016575033.1"
                     /locus_tag="IGS71_RS26515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_54210"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_190852468.1"
                     /transl_table=11
                     /translation="MKKIVLGDVEVSRVVEWQGAFATTDVLFPSVPGELWRRHESWLAP
                     DFLNSRTGAWQANVQTWVLRSAGRTILVDTGLGNDKQREVEVFNKLDGDFLDRLAAAGV
                     RPEDVDLVVNTHLHNDHVGWNTRLVDGEWVPTFPNARYLISRADFDFWNPANGHVPKSP
                     FQSASDTGVTFEDSVLPVHQAGQAVLWEGDSHRIDEDLVLEPAPGHTPGSTVLWLESGI
                     DRAVFVGDLVHTPLQMIEPDHDTCLSEDRTEATRSRRRVLERAAATNSLVVPAHLGGAG
                     AAEVVRSNGAVSIKRWAPFSDA"
     misc_feature    5757..5772
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.81"
                     /tool="antismash"
     misc_feature    complement(5759..5773)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.93"
                     /tool="antismash"
     misc_feature    complement(5760..5775)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.01"
                     /tool="antismash"
     gene            <5907..>6126
                     /locus_tag="IGS71_RS26520"
                     /pseudo=""
     CDS             5907..>6126
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143667.1"
                     /locus_tag="IGS71_RS26520"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="IS630 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVIRSGREALRCLLARRGIAVRRTRTGKESPDPERDAELDRIEHV
                     LDHFPDRVFAFDEFGALGIRPHRRLVLG"
     misc_feature    5934..5936
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6304..7017)
                     /locus_tag="IGS71_RS26530"
                     /old_locus_tag="GCM10017557_54230"
     CDS             complement(6304..7017)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="IGS71_RS26530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_54230"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_190852469.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 9.1e-10, bitscore:
                     38.4, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 2.9e-06, bitscore: 26.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVTAVAVTAVAVTAQDAPAAPGPGPGFTLRTITQKVSLTGSGPA
                     DQTLSAVEYQPGHARVKGNQVMIPGVTYDHRYFDLKTNRGWISQARKAAEDGWITVAVD
                     RLGTGDSSSPAAHRLNATTHSATIHQLITKLRTDHKGLPVALVGHSMGSVVAIQEAASY
                     KDVNVPVLSLVGRHDGLYFDPADLNTTLKAETGAYPASPDVDVKSIPGAGHDLALQRNA
                     DSTIDIINTWLSRKL"
     misc_feature    complement(7225..7243)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.88"
                     /tool="antismash"
     gene            complement(7313..8185)
                     /locus_tag="IGS71_RS26535"
                     /old_locus_tag="GCM10017557_54250"
     CDS             complement(7313..8185)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016575889.1"
                     /locus_tag="IGS71_RS26535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_54250"
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="WP_283842980.1"
                     /transl_table=11
                     /translation="MNTPPASLPGGTWTLGDLTVTRFGYGAMQLAGPGVMGPPADHDGA
                     LAVLREATDLGITHIDTAGAYGPRVTNQLIREALHPYPASLHIVTKVGADRDQQGGWPP
                     ARQPEDLRRAVHENLADLGLDALDVVNLRLGDAQGPVPGSLAEPFETLVELQRQGVIRH
                     LGVSNATAEQVTEAQAIAPIVCVQNMYNLAYRQDDELIDELADQGIAYVPFFPLGGFTP
                     LQSTALSAVATRLDATPMSVALAWLLGRSPNILLIPGTSSVAHLRENVAGAGLPLSDED
                     LAELDKIGR"
     gene            8395..9258
                     /locus_tag="IGS71_RS26540"
                     /old_locus_tag="GCM10017557_54260"
     CDS             8395..9258
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007388521.1"
                     /locus_tag="IGS71_RS26540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_54260"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_055513377.1"
                     /transl_table=11
                     /translation="MDTLETRELRYFVAVAEELHFGRAAERLGMAQPPLSRAIQQLERR
                     LGVLLLERNRRGVSLTAAGEMLLHEGRAALDATTAAARRTRRAGGADSPGGPRNRLVLA
                     VKAGASHELLHKLIDAYAAEPDSAEIEVLPSGTCEQGEMLRDGRADVALMHKPFNSLAG
                     FDSEELMTEGQIAILPTGHPLAAHKSLSLADVSDIPDLPLARWAHDGTYPPGPGPEIHD
                     QTQLAQLIALGRTAAVFPDSARAWLWAEHTAVPLADAPPVVTHIAWPAHSRSLALAGLI
                     RTATRL"
     gene            9266..9499
                     /locus_tag="IGS71_RS26545"
                     /old_locus_tag="GCM10017557_54270"
     CDS             9266..9499
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IGS71_RS26545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10017557_54270"
                     /product="hypothetical protein"
                     /protein_id="WP_190852471.1"
                     /transl_table=11
                     /translation="MPSTAAVTLLGFGPNNCGSLCVRGGHRHWARVLEVFPERYAEAER
                     QEQELRAELGDVAILRDRTGGCQAFAPSTSKC"
     gene            complement(9591..9842)
                     /locus_tag="IGS71_RS26550"
                     /old_locus_tag="GCM10017557_54280"
     CDS             complement(9591..9842)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IGS71_RS26550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10017557_54280"
                     /product="hypothetical protein"
                     /protein_id="WP_055513381.1"
                     /transl_table=11
                     /translation="MSASGFEPPHTSPEARARITSALLAHGWERGAIKEVFDLYDSELA
                     RQIREERKAVEAENVASHAYLFDGMDYAADIIDPHSPS"
     gene            complement(10001..10432)
                     /locus_tag="IGS71_RS26555"
                     /old_locus_tag="GCM10017557_54290"
     CDS             complement(10001..10432)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016638989.1"
                     /locus_tag="IGS71_RS26555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_54290"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_079103564.1"
                     /sec_met_domain="PF13471 (E-value: 2.2e-29, bitscore:
                     100.7, seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQILDTDGSRPGFGTRLTAHTAVTAARLLARLPPRRLRTVLGLA
                     RRGARPARYDEALRARQDVTAVSTLCAGRYCLPRSLATALLCRMRGHWPTWCSGVRTTP
                     FGAHAWVEADGRPVGEPSDTATYRPMITVSAADRDSTEG"
     gene            complement(10429..10686)
                     /locus_tag="IGS71_RS26560"
                     /old_locus_tag="GCM10017557_54300"
     CDS             complement(10429..10686)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lasso_Fused_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016638988.1"
                     /locus_tag="IGS71_RS26560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_54300"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_347342167.1"
                     /sec_met_domain="Lasso_Fused_RRE (E-value: 2.2e-10,
                     bitscore: 39.3, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1e-24,
                     bitscore: 85.2, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4.6e-12, bitscore: 44.9,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHRLRADVTACATGDSMVLLDERSGRYWQLNGTGALVVKFLLEGV
                     TPEQAAERLAATRPVTPERATADVTALVAHLVKEKLVTDS"
     aSDomain        complement(10438..10683)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_IGS71_RS26560_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="3.60E-27"
                     /identifier="RREFam002.1"
                     /label="IGS71_RS26560"
                     /locus_tag="IGS71_RS26560"
                     /protein_end="83"
                     /protein_start="1"
                     /score="85.2"
                     /tool="antismash"
                     /translation="HRLRADVTACATGDSMVLLDERSGRYWQLNGTGALVVKFLLEGVT
                     PEQAAERLAATRPVTPERATADVTALVAHLVKEKLVT"
     aSDomain        complement(10519..10686)
                     /aSDomain="Lasso_Fused_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing fused peptidase in a lasso
                     peptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_IGS71_RS26560_Lasso_Fused_RRE.1"
                     /evalue="7.60E-13"
                     /identifier="RREFam003.1"
                     /label="IGS71_RS26560"
                     /locus_tag="IGS71_RS26560"
                     /protein_end="56"
                     /protein_start="0"
                     /score="39.3"
                     /tool="antismash"
                     /translation="MHRLRADVTACATGDSMVLLDERSGRYWQLNGTGALVVKFLLEGV
                     TPEQAAERLAA"
     gene            complement(10667..12526)
                     /locus_tag="IGS71_RS26565"
                     /old_locus_tag="GCM10017557_54310"
     CDS             complement(10667..12526)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.4"
                     /locus_tag="IGS71_RS26565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_54310"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_190852473.1"
                     /sec_met_domain="Asn_synthase (E-value: 4.7e-30, bitscore:
                     104.3, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAATPAYWFVVLPDRDLAPGLLGRLRDLAGRAVLRTVPHASGRPW
                     LAGCWPDEELAACAVGDVRLAVAGTCSLQPAELAARARQISQSAHIEPVLRDAHGCFHL
                     LASVAGHTYVRGSFSGQRRVYRAEAGGGTVCASHARVLARLTAAELDTAQLALRLTGDT
                     IAHPLGWDALWRGVHAVLPGTAMELTPGGEVRTRRWWQPPAADLPLDEAAAGLREALER
                     AVASRVRPGEVVGADLSGGMDSTSLCFLAAQAGARLVAVTLDAGAPTNEDRLFATRAAG
                     HLPGVEHLVFASADLPAQFSGLDECVDPGDEPSAIVRTRVEQRYLAGQMRAHGARLRLS
                     GFGGDQVIQSPPSYVHGLLRRSPVAGLRHAAGWRARHRRPLGALTKALLDRGSYAAWLT
                     EAAGMLRTPVSGDDLRWGLRPSLPSWASERAVQLCRERLLGAARDAAEPLHPERGRHAW
                     LASAQRGGRLAGPLAHRGQLDRLPYHSPFCDDAVIAAALAARPHEAAGPWSYKPLLAAA
                     MHGLVPEAVLRRTTKDHFGYEWHNGLRHNRRTLAAWAEDSRLVAAGLADEDALRRALLS
                     PQLLLGGTAEFETTLGVEAWLRGLEHPHTPDGTREMNSAPTTR"
     gene            complement(12622..12759)
                     /locus_tag="IGS71_RS26570"
                     /old_locus_tag="GCM10017557_54320"
     CDS             complement(12622..12759)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014140851.1"
                     /locus_tag="IGS71_RS26570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_54320"
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_245702316.1"
                     /transl_table=11
                     /translation="MQETLQGFETTDVYEPPLLAEVGQYAELTQGEFGDWPDYPVGLWL
                     "
     gene            complement(13111..13422)
                     /locus_tag="IGS71_RS26575"
                     /old_locus_tag="GCM10017557_54330"
     CDS             complement(13111..13422)
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1026: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF025063.4"
                     /locus_tag="IGS71_RS26575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_54330"
                     /product="integrase core domain-containing protein"
                     /protein_id="WP_190852475.1"
                     /transl_table=11
                     /translation="MVHSDRGSGYASAQFRAHVRELGPRSSCGRTGSCFDNAAAESFWA
                     LLKEEIGTRIWPDRAAARAEVFAFIETFYNRRRLRKHKTFGYLTPAETRQRHRHALAA"
     misc_feature    13487..13501
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.25"
                     /tool="antismash"
     misc_feature    13874..13889
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.91"
                     /tool="antismash"
     misc_feature    complement(14122..14137)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.28"
                     /tool="antismash"
     tRNA            complement(14249..14324)
                     /anticodon=(pos:complement(6221664..6221666),aa:Arg,
                     seq:tct)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="IGS71_RS26580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GCM10017557_t00540"
                     /product="tRNA-Arg"
     gene            complement(14249..14324)
                     /locus_tag="IGS71_RS26580"
                     /old_locus_tag="GCM10017557_t00540"
     gene            14646..16253
                     /locus_tag="IGS71_RS26585"
                     /old_locus_tag="GCM10017557_54350"
     CDS             14646..16253
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016435092.1"
                     /locus_tag="IGS71_RS26585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_54350"
                     /product="dynamin family protein"
                     /protein_id="WP_190852477.1"
                     /transl_table=11
                     /translation="MVTLDVRPQLLDALSALRDRVAAARFPLPLAGAPRARANRDELIA
                     QLDDYLVPRLRQPEAPLLAVIGGSTGAGKSTLVNSLVGRRVSQAGVLRPTTRTPVLVCH
                     PEDHHWFSGMRVLPDLTRVWMPRQDVDDDPLLSAEDDLRVLRIETVDTLPRGLALLDAP
                     DIDSLVADNRVLAAELMCAADIWVMVTTAARYADAVPWHLLRTAKEHDATLVTVLDRVP
                     HQVVAEVSRQFGALLAKAGLGDVPRFTVPELPESAWGGGLLPATAVAPLRAWLAQQAQD
                     PGARQQVMARTAYGVLDSLKSRMPELAGAAAAQYAAALRLTAAVDGAYDSEYTRLRGRL
                     QAGAVLAGDALKRWRSYPLDCSAGELLDALAESLAALLLCAVTAADERVDEAWRREPAA
                     GAPGLTDRDPTLESAEHRIGMAVRRWRRVLEEHAEDEVRALEKSVAPDPEVVAALVATA
                     LLGGRRARSAGEGLAERIGAHGALRLRDKGGRLLTDYLDKALHDERERRLAPLDALDVH
                     PEPQAELIAALSVLQKER"
     misc_feature    16258..16273
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     gene            16259..18328
                     /locus_tag="IGS71_RS26590"
                     /old_locus_tag="GCM10017557_54360"
     CDS             16259..18328
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013003512.1"
                     /locus_tag="IGS71_RS26590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_54360"
                     /product="YfjP family GTPase"
                     /protein_id="WP_246596534.1"
                     /transl_table=11
                     /translation="MTAVTDHTDHSDQPGDDEGREGEGREGEGRQERGHARVEDDSVTD
                     RRNAYKNAHKEDPGGEAVRKEKGDSGRVRTETGGGAESGSGSGAGAGPGAGGGSVEAAV
                     GEDEAVGSGMDAVDATDSAGAWDDGLIARRVSVTAEGQTRAVQEIVVDNRSPAVTPLAY
                     DGPLRSRLDALRELVGLSRTRLDNRTLAEAGRVLDEAAARRRLSGQHTVVAIAGATGSG
                     KSQLFNALAGVAISETGVRRPTTAAPIACSWSDGAAGLIDRLGVPGRLRRRPLQSAEAE
                     AQLRGLVLVDLPDHDSAALQHREHVDRMLALVDAVIWVVDPEKYADAVLHERYLRPMAG
                     HAEVTFVVLNQIDRLPGEAADQVLDDLRRLLDDDGIALGEYGEPGATVLALSALTGEGI
                     GELREALGHFVAERGAAARRISADVDAAAVRLWPVYANRRQAGLSEEARDEFADRLADA
                     VGATAAGEAAERAWRRNAGRACGTPWLRLWRWYQDRREPPTGRLSVRPHDEEATARQRV
                     EQAVRTVAERAADGLPSPWAQAVREAAVRGSQGLCEALDELAVRAGAPVGRPPRPGWWP
                     AAVLAQAAMTVLQVVGGLWLAGQVIGFMSPNLGVPVLLMVIGIVGGPGVEWACKLAASG
                     PARRYGLDAERRLREAAAGCGRARVLDPVAAELLRYREVRGQFLRATGVDAPVG"
     misc_feature    complement(18507..18521)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.88"
                     /tool="antismash"
     gene            18606..19136
                     /locus_tag="IGS71_RS26595"
                     /old_locus_tag="GCM10017557_54370"
     CDS             18606..19136
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006379520.1"
                     /locus_tag="IGS71_RS26595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_54370"
                     /product="single-stranded DNA-binding protein"
                     /protein_id="WP_190852481.1"
                     /transl_table=11
                     /translation="MNETMVCVVGNVATQPVFRETAAGASARFRLAVTQRYWDREKNAW
                     RDGHTNFFTVWANRALASNVQASVALGEPLVVRGRLKVRSEQRDGQSWAGADIEASAIG
                     HDLARGTAAFRRTLRGDQASDQTSDGASEQAPDLASGQASGTPARPEPSWETEPTDQAD
                     EAARQGQEPALAT"
     misc_feature    complement(19245..19256)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.25"
                     /tool="antismash"
     misc_feature    complement(19245..19260)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.54"
                     /tool="antismash"
     gene            19459..20814
                     /locus_tag="IGS71_RS26600"
                     /old_locus_tag="GCM10017557_54380"
     CDS             19459..20814
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020116474.1"
                     /locus_tag="IGS71_RS26600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_54380"
                     /product="TQXA domain-containing protein"
                     /protein_id="WP_055513424.1"
                     /transl_table=11
                     /translation="MAAVALVSGLVAVSAATTAGAAVADELPLSQGGATATIGGLKASG
                     PAVIHEDGGDKQVSAGLFEMSVDNGGTLQTYCVDIYSPTQKDAKYQETPWSGTSLNENP
                     DAGRIRWILRNSYPQVNDLAALAAKAGASGLTEQDAAAGTQVAIWRYSDGADVDAVDPQ
                     AEKLADYLQRSARDLAEPAASLSLDPPAVSGHPGELLGPVTVRTNADGVTVTPPADATS
                     GVRIVGRDGKEITSAVDGGELYFDVPEDAADGSVALTVQASTTVPVGRAFASETRSQTQ
                     ILAGSSESTVSAAATANWAGSGAIPALSAEKNCAEGGLDITAVNEGDEAFTFELMGSEH
                     TVEAGTSRTVTVPLQEDQTYDVTVEGPGGYEKRFQGVLDCRTQSGVGGETVQTLNEPSP
                     ATVGGTSAATTDLAETGTSSATPVIAGIAIGLVLIGGAAVLFVRKRKTPTQD"
     misc_feature    complement(21886..21901)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.33"
                     /tool="antismash"
ORIGIN
        1 ggaggaggcc gtggaccggc tctccgccga atccgacacg ctcttcgtcg tggcggcggg
       61 aaacgacggt gagttcggcg agggcacggt cggctcgccc ggcagcgcgg acgccgcgct
      121 caccgtgggc gcggtcgaca agtccgacgc gctcgccgac ttctccagtc gcggcccgcg
      181 ggtcggcgac ggcggcgtca agccggacct gaccgcgccc ggtgtcgaga tcacggcagc
      241 ggcggcggcc ggcagcatca tcgaggagga gttcccctcc ggcgtccccg gctacgccac
      301 cctcgaaggt acgtccatgg cgaccccgca tgtcgcgggc gccgccgccc tcctcgccca
      361 gcagcatccc gactggagcg gcgagcgtct caaggcggtc ctcaccggct ccgcgaagcc
      421 ggggacgtac agctccttcc agcagggcac cggccgtacc gatctggtcc gggcgctggg
      481 acagaacgtc gtcacggagc aggggccgct cgacttcggc gagcagcagt ggccgcacga
      541 cgacgacaag ccgtccgcca agcagctcac ctaccgcaac ctcggcaccg agccggtcac
      601 cctcgacctg tccgtcgatg ccttcgcggt ggacgggaag cccgccgccg agggcatgtt
      661 cagcgtgtcc ccgcagcgga tcaccgtccc ggcgggcggc accgcgagcg ccgaggtcac
      721 ggcggacacc cgcgcgggga gcaccgacgg cagcttcggc ggttcggtgc aggccacgtc
      781 ggcggacggc aaggtccagg tgcggtccgc catgggtgcg gcgcgcgagg tggagtcgta
      841 cggcctgacg ctcaagcaca tcgacgagaa cggccggccg accggggacg ccgccaccgc
      901 cgtcgccgat ttcgacggcg acttctacgg cgagtacgcc gacgagcagg acggcgagct
      961 gacggtacgg ctgcccaagg gcgactacat cctcagcggg gtcgtccacc cggggacctc
     1021 gtcgcccgtc cacggcattc tggtggagcc gaggttccgg ctggacggcg acaagaccgt
     1081 caccgtggac gcccggcagg cgaagccggt ggacatcacc gtgccggacc cgacggccga
     1141 gaacaccgac gccagcgtcc tgatcggctt cgggcgcggc gagggcaagc gtgacggttc
     1201 attccagtac ctgatgccgg gcttccaggg ctcgcggttc gggcggctcg gcggcgggga
     1261 gcccgtggac ggtctcaacg ccctgtactc cggcggctgg agcggccggg gcacgaacgg
     1321 cgaccgggtc aactaccacg cggcctggtt gcgggagggc agtctggacg gcttcaccgc
     1381 caaggtcgag cggaagcagt tggcgaaggt cgacctccag gtgggcgagc cggtcgacgg
     1441 ccgacgcgtc caggccgagg tgagcccgca cctgccggac ggcgaacttg tgtacggctt
     1501 caccggcatg gggggcgacc tgccgttccg gagcaccgag tacatcctcg acaacggtgt
     1561 gaagtggtcc atgcgcacct ggcaggtctc gggcgaggac caggacaagg tcttcgagaa
     1621 cttcctcatg cggatgccgc agacctggaa ggccggtcac agctaccagg agcgcttcaa
     1681 cgtcgccgtc ttcggcccgg cgccggccgg caccggacag ttcggaccgg ccagtggctt
     1741 ccccggtgtc gcccgcatgg ggaacaccgt cagggcgtat gtcccgctgt tcggtgacgg
     1801 cagcggacac tggggcacca gcgacacgac cgccgtgacg accagactgg aggcggacgg
     1861 caaggagatc gccgacgact acggcatccc tccgaccgac ggcctcaccg agtacacggt
     1921 tccggcagac gacaccacgt acaagctgac cgtggacaac tcccgtgacc cggccgtgta
     1981 tccggtcagc acccgcgtcc gcgcggagtg gaccttccgc tcggcgaaga ccccggacga
     2041 cgagttcacc gctctgccgg tgtcgacggt ccgcttcagc cccgacgtga ccctggccgg
     2101 cacggcgaag gcgggcaagc gcttcgaggt gcccttcacc gtcgagggcg cggcggcggg
     2161 acagcgcccg gcgaagctcg ccttccaggt gtcctacgac gaggggaaga cctggcagtc
     2221 cgccaagtcc ctcggcggta cgcacctgtc gctgaagcac ccggcgacgg caggctccgt
     2281 ctccctgcgc gcggagctga cggaccgggc gggcaacacc ctcacccaga cgatagaaag
     2341 ggcctacctg accaccccgt agctccctgt acccacacct gcccgggacg gtctcgccgc
     2401 tgtcccgggc aggtgtgttc acgtctgcgg ccgaggctca acaggccgcg gagatccatc
     2461 agaaggctca ggaaccggcc acgtccgtgg gtgcggtcca gccggtggcc cggatccact
     2521 cggccaggtc cagggtggcc ggctcgatcg agcgcaccac cgcaggatcc gaagggtact
     2581 ccgccgcctg cgcgaactcg cggaacatca ccctgtcgag gtcggtggga agcacgctca
     2641 acgggagggc ctcgtaccgt gccgggagcc cggcgtgcgc gccgaacacc gcggcgatct
     2701 gggggcccgt caggtcgtcg ccgacgagct cgacggctcc gccgggcgcc tccgcggtgc
     2761 cgagcaggag cgcggcggcg acccggccga tgtccctgac cgagatcatc ttcaggggga
     2821 cgtcctccgg caggggcagc ctcagcacga tctccccatg ttccaggctc ggtgccatca
     2881 cgctcgcgaa gttctccatg aaggcggtcg cgcgaaccat cgaggccctc aggccggact
     2941 tcctcaggtg ctcctcgatc cagtgcttcg agtcgtggtg cggcacgccc gactcccggt
     3001 ccgctccgaa gaccgagttg aacacgacgt gcgggacgcc cgcctcgacc gccgcgtcga
     3061 cgagcgcggt accgatgcgg atctccgcct cgacctcttc gaggctgttc gcctccgggg
     3121 tcatgaagta gaacgcctcg accgtcgcca gcgcggcggc cagcgacgcc gggtcgtcgg
     3181 cccggacggc cgccggctcg acgccgcggg cggccagcgc ctgagcccgg tcggactgcg
     3241 ggtcgcggac cagggcccgt acccgcgcct tgtggtccag cagcgcgtcg accaccgccc
     3301 cgccctgttg ccccgtcgcg ccgaagactg cgatcgtgcc ggtcgtctgt gtgctcatcg
     3361 ctgccaccct tcagtagttc atggcgtgaa cgaaactagt tcacgccatg aactacgtca
     3421 aggtgcgggt gcggcgggtg cagcgggacc tcacggtgtg acgggtgggt ccgtggtggg
     3481 cgacgagagg tctgaggtgt ccacgatggc ggtggccacg cgctcgaagt cgcgctggtc
     3541 gtcggcgtcg aggttcctcg cgatctcggg caggcgcttg gcgatctcgg cgtagatggc
     3601 ctcggcgagc accttccccg tgggcgtcgc actgagcatg acgacccgcc ggtcctgcgc
     3661 cgagcttgcc cggccgacca gctcgcgccg cgcggtgcga tcgaccagct ggctcaatgc
     3721 gttcttggtc atacccaacg acgcggcgag gtcagccatc tgccgcggct cgttcctgac
     3781 ggcgcagatc agcgtggcct gcgagggggt caggtcgaac ccggcgcaga tctgcgcgta
     3841 cttgcgttga atcacgaccg agagccagaa gagcttgtcg ccatagtcca cgccggcctc
     3901 ccccggtccg atgacgaacg aacgatcagc ctactcgtcg cgggcctgca gaccacgcca
     3961 ctcaccagga gatgcacacc tccgcgagac cggcgtggtg gtcggtgcgg tgctgctgcc
     4021 ggtaacggcc ggctgaggtc ccgtactcgc gtttgaaagc gttggcgaag gcatagacgg
     4081 agccgtagcc gctgcgctgc gccacggtga acagcgggac gtcggtcgtc tggagcaggc
     4141 gtgccgccgt ggtgagccgc caccacgtca gataggtgag cggtggctgc cccaccaggg
     4201 cggtgaacct acgggcgaag gcggcacggg acaggcccgc gtgcgcgccc agcgactcca
     4261 cggtccaggg atcggcgggg cgttcgtgca cggcacggag tgatcgcgcg atcacctcgt
     4321 cgtcgagggc gacgcaccag ccggtggcct gcagccctgc acgttcgatc aggcaggccc
     4381 ggatcaggtg cacgaggagc acttcgagca gcgccggcag caccaggtcc ctgccgtgca
     4441 tctgttcgcc cagttcgctg agcaacaggt cgatcgacgc ctggagaccc gggtagcgat
     4501 ccggccgcgc cggaaggctc accacatcgg cgaggtcctg gaacagcggg tgcgggcggg
     4561 cccgctcaag ccggtaggca ccggacaaga actgggcagt gctgtcggtg gcgctcacga
     4621 gcgtgtgcgc agtcccgtgc gggagcagta cggcgtcgcc cggtagcaag gtgatgaccg
     4681 cttcgcccgg tgccgtcacc cggatgcgtc ccgtggtgcc cacgtagaac cgggcaccct
     4741 cgaaggtctg gacctccctc tcctccgacg ggtccgccgc ctccagcgac agggaggggc
     4801 gccccactcg catggtgccg atcgcgtcgc tgagcacgtc catggccgca tcttccctta
     4861 ccgggtcagg cgtccgagaa cggcgcccat cgcttgatcg agacggcccc gttcgaccgt
     4921 acgacttcgg cggcacccgc tccgcccagg tgcgccggca cgaccaggct gttcgtcgcg
     4981 gctgcccgct ccaggacgcg acgccgggac cgggtggcct cggtccggtc ctcactcagg
     5041 caggtgtcgt gatcgggttc gatcatctgc agcggggtgt ggacgaggtc gccgacgaat
     5101 accgctcggt cgatgccgga ctccagccac agcaccgtcg aaccgggcgt gtgaccgggg
     5161 gccggttcca ggaccaggtc ctcgtcgatg cggtgactgt cgccctccca cagcaccgcc
     5221 tgaccggcct gatggacggg caggacgctg tcttcgaacg tgaccccggt gtccgaggcg
     5281 gactggaacg gagacttcgg gacgtggccg ttggcggggt tccagaagtc gaagtcggcc
     5341 cggctgatca gatatcgcgc gttggggaac gtcggcaccc actcgccgtc gaccagccgg
     5401 gtgttccacc ccacgtggtc gttgtgcagg tgggtgttga cgacgagatc cacgtcctcc
     5461 ggccgcaccc cggccgccgc cagtcggtcg aggaaatcgc cgtcgagctt gttgaacacc
     5521 tcgacctcgc gttgcttgtc gttgccgaga ccggtatcga ccagaatggt gcggcccgcg
     5581 cttcgcagca cccaggtctg cacgtttgcc tgccacgcgc ccgtcctgga gttcaggaag
     5641 tcgggcgcca gccaggattc gtgccggcgc cacagttcgc cgggcacgga cgggaacagg
     5701 acatcggtgg tggcgaaagc accctgccat tcgaccaccc gcgagacctc gacatcaccg
     5761 agaacgattt tcttcaccac gtcaccgtag gaagaaacgg tgagacgcga aatgctccga
     5821 cgtctctctt tgttaagcga gcgtcttgcg ggagttctcg aacgtcccgg ccgccgcgtg
     5881 tgaccagcct gctggtgcgt tggttccgcg tcatccggag cggccgcgag gcgttacggt
     5941 gcctgctcgc tcgccgcggc atcgccgtcc ggcgcaccag gaccgggaag gagtccccgg
     6001 accccgagcg cgacgccgag ctcgaccgca tcgagcacgt cctggaccac ttcccggacc
     6061 gcgtcttcgc gttcgacgag ttcggcgcgc tcggcatccg cccccaccgc cggctcgtcc
     6121 tgggccgggg caaggtcctc gcgccgcgcg acgtgtgccc ggacaccggg ctggtccggc
     6181 tgtcgtacgg gcaggcccgt gtgccgctgg acgagcacac cgccctcggc gacagaagcg
     6241 gcaccggttg gggtctgcac cccctgctgc cccggggctt gcggggagcc gggttgcgtc
     6301 ctcctagagc ttgcgggaca gccatgtgtt gatgatgtcg atggtgctgt cggcgttgcg
     6361 ctggagggcc aggtcgtggc cggctccggg aatggacttc acgtcgacgt cagggctggc
     6421 cgggtaagcg ccggtctccg ccttgagggt cgtgttcagg tcggcgggat cgaagtacag
     6481 gccgtcgtgc cggcccacga gcgacaggac gggaacgttg acgtccttgt aggacgcggc
     6541 ttcctggatg gcgaccacgc ttcccatgga gtggccgacc agtgcgaccg gcagcccctt
     6601 gtggtcggtc ctcagcttgg tgatcagttg gtggatggtg gcggagtgag tcgtggcgtt
     6661 cagccggtgc gcggccgggc tgctggagtc gccggttccg aggcggtcga cggcgacggt
     6721 gatccagccg tcctcggccg ccttgcgtgc ttgcgagatc cagccgcggt tcgtcttgag
     6781 atcgaagtac cggtggtcgt aggtgacgcc cgggatcatc acctgattgc ccttcacgcg
     6841 ggcgtgtccc ggttggtatt ccacggcgct cagcgtctgg tcggccggtc cgctgccggt
     6901 gagcgagacc ttctgggtga tcgtgcggag ggtgaaaccc ggcccggggc cgggggcggc
     6961 gggcgcgtct tgggccgtga cggctacggc cgtgaccgct acggccgtga cgagcaacgc
     7021 ggcggacgcc gcgtcctcgg agcggctgcg ggagcagttc taaggagtgg tgtggcggtt
     7081 ccgcaccggc agtccgtggc gggacatgcc tgctgatcac gacgcctgga cgacggccta
     7141 tcaccgggtt ttgcagtggc acgacttgga ccgaccggta attggggggg ggtgcgtgcc
     7201 cagcccccgc gacgtcgccc cccaattgcc ggtcggtctc aaggtgtctg aggtcctcgg
     7261 ctccctgatc cgcagcctcc gcctcaccgg gtgatcccac ccggaacagg tcctaacggc
     7321 cgatcttgtc cagctcggcg aggtcctcgt cggagagcgg gagtcccgcg ccggcgacgt
     7381 tctcgcgcag gtgcgccacc gaggaggtgc cgggaatgag caggatgttc ggtgaccgcc
     7441 ccagcagcca ggccagggcg accgacatcg gcgtcgcgtc cagccgggtg gccacggcgg
     7501 acagcgccgt ggactggagc ggggtgaagc cgccgagtgg gaagaaaggc acgtaggcga
     7561 tgccttggtc ggcgagttcg tcgatcagct cgtcgtcctg gcggtaggcg aggttgtaca
     7621 tgttctgcac gcacacgatc ggtgcgatcg cctgcgcctc ggtgacctgt tccgccgtcg
     7681 cgttgctcac tccgaggtgc cggatgacgc cctgccgctg gagttcgacg agggtctcga
     7741 agggctcggc gagcgagccg ggcacggggc cctgggcgtc gccgagccgg agattgacca
     7801 cgtcgagcgc atcgaggccg aggtctgcaa ggttctcgtg gacggcgcgg cgcaggtcct
     7861 cgggctgtcg ggcggggggc cagccgccct gctgatcgcg gtccgcgccg accttggtca
     7921 cgatgtgcag cgatgcgggg taggggtgca gtgcttcacg gatcagctgg ttggtgacac
     7981 gcggtccgta tgcgccggcg gtgtcgatgt gggtgatccc gagatcggtg gcctcgcgca
     8041 ggacggcgag cgcgccgtcg tggtcggcgg gcgggcccat gacgccgggg ccggcgagct
     8101 gcatggcgcc gtagccgaag cgggttacgg tcagatcgcc cagggtccag gtgccgccgg
     8161 gcagtgacgc ggggggtgtg ttcatggctg tgtctttcct gctgagccgg atacttcgga
     8221 gggctgtggg tcgcgtggcc cgtcgctcgt cgacggcgcc ttgtccgcgt cagctaccgg
     8281 agcggactgc ggctccccat ggcgtcgatg ttcgctcgcc gaccagcggc gcagccaata
     8341 ccgacacggt gccctgtcat acccggcgag tatcacggag ttaggctggg gcccatggac
     8401 accttggaga cccgcgagct gaggtacttc gtggccgtcg cggaggaact ccacttcggc
     8461 cgcgccgccg agcgcctcgg catggcccag ccaccgctct cccgggccat ccagcagctt
     8521 gagcggcgcc tcggcgtcct gctgctggaa cgcaaccgtc gcggagtctc cctcaccgcc
     8581 gccggagaga tgctgctgca cgagggccgc gcagccctcg acgcgaccac cgccgccgct
     8641 cgccgcaccc gtcgcgccgg tggcgccgac agtccgggcg gcccccgcaa ccgcctggtc
     8701 cttgcggtga aggccggcgc gtctcacgaa ctgctgcaca agctcatcga cgcctacgcg
     8761 gccgagcccg actccgccga gatcgaggtg ctgccgagcg gcacatgtga gcagggggag
     8821 atgctgcgcg acggccgcgc cgacgtggcg ctcatgcaca aaccgttcaa ctccctcgcc
     8881 gggttcgaca gcgaggaact gatgaccgag gggcagatcg ccatcctgcc caccgggcac
     8941 cccctcgccg cgcacaagtc cctgtccctg gccgacgtca gcgacatccc cgatctgccg
     9001 ctcgcccgct gggcccacga cggcacgtac ccgcccggcc cgggccccga gatccacgac
     9061 cagacgcagc tggcccagct gatcgccctc ggacgcaccg cggccgtctt ccccgactca
     9121 gctcgcgcct ggctgtgggc cgagcacacc gccgtacccc tggccgacgc accccccgtc
     9181 gtcacccaca tcgcctggcc cgcgcacagc cgctccctcg ccctcgccgg gctgatccgc
     9241 acagccaccc gactatgacc ctctcgtgcc ttccaccgcc gccgtcaccc tgctcggctt
     9301 cgggcccaac aactgcggct cgctgtgcgt ccgtggcggc caccggcatt gggcccgcgt
     9361 actggaggtc ttccccgagc ggtacgcgga agccgaacgc caggagcaag agctgcgagc
     9421 cgagctcggc gacgtggcga tcctgcgtga ccggaccggc ggctgccagg ctttcgcccc
     9481 gtcgacgtcg aagtgctagc cgaccatgcc cagcttcgcg acgcggtcgg cgtccagtgc
     9541 agcccgctcc cggcatttct cggcctcggg ggttcgcagt ccccagtgcg tcagctcggc
     9601 gagtgcgggt cgatgatgtc ggccgcgtag tccatgccat cgaagaggta agcgtgcgag
     9661 gcgacgttct cggcttccac ggccttgcgc tcttcgcgga tctgccgtgc cagttcgctg
     9721 tcgtagaggt cgaacacctc cttgatcgcc ccgcgctccc acccgtgcgc gagcagggcg
     9781 gaagtgattc tcgcgcgagc ctccggagag gtgtgaggcg gctcgaagcc ggatgcgctc
     9841 atgcggtctg ctcccagcgc tcggcccggg ccttgtctgt cgatccgtcg gccccgtctt
     9901 ggcggggcgg tcgcgcacgg gctcctcacc gcgcttgtcg ggcggagctg cggcgagcga
     9961 tgcggctggg tcaccgacag gggcggtgtt gctggcggca tcagccctcc gtgctgtcgc
    10021 ggtccgccgc cgacacggtg atcatcggcc ggtaagtggc ggtatcagat ggttcgccga
    10081 cgggtcggcc gtcggcttcg acccaggcgt gggctccgaa gggtgtggtg cgtactccgc
    10141 tgcaccaggt gggccagtgg ccgcgcatcc ggcacagcag ggcggtggcc agggagcgtg
    10201 ggaggcagta gcggccggcg cacagggtgc tgaccgcggt cacgtcctgc cgggcgcgca
    10261 gcgcctcgtc gtagcgggcg ggcctggctc cgcgccgggc caggcccagt acggtacgga
    10321 gccggcgtgg tggcagacgg gcgaggagcc gggcggcggt gacggcggtg tgggcggtga
    10381 gccgggtgcc gaagccgggg cgggagccgt cggtgtccag gatctggctc acgagtcggt
    10441 caccagcttc tcctttacga ggtgcgcgac cagcgcagtc acgtcggcgg tggcgcgctc
    10501 gggggtgacc gggcgggtgg cggcgagccg ttcggcggcc tgctcgggcg ttacgccctc
    10561 cagcaggaac ttcaccacga gggctccggt gccgttcagc tgccagtagc gtccgctgcg
    10621 ttcgtcgagc aggaccatgc tgtcgcctgt ggcgcaggcg gtgacatcag cgcgtagtcg
    10681 gtgcactgtt catctccctc gtaccgtccg gggtgtgcgg gtgctccagg ccgcgcagcc
    10741 acgcctccac tccgagggtg gtctcgaatt ccgcggtccc gccgagcagc agctggggcg
    10801 agagcagggc acggcgcagg gcgtcctcgt cggccagtcc ggcggccacc aggcgggagt
    10861 cctcggccca ggctgcgagc gtgcgccggt tgtggcgcag gccgttgtgc cattcgtatc
    10921 cgaagtggtc cttggtggtg cggcgcagga cggcctcggg caccaggccg tgcatggcgg
    10981 cggcgaggag aggcttgtag gaccaggggc cggcggcctc gtgcgggcgg gcggcgagcg
    11041 cggctgcgat gacggcgtcg tcgcagaacg ggctgtgata gggcagcctg tcaagctgcc
    11101 cgcggtgggc cagagggccg gcgagccggc ccccacgctg cgcggaggcc agccaggcat
    11161 ggcgcccgcg ttctggatgc agcggctcgg cggcgtcccg ggccgcgccg agcagccgct
    11221 cacggcacag ctgaacggcc cgctcgctcg cccaggacgg aagagaggga cgcagccccc
    11281 agcgcagatc gtctccggac accggcgtgc gcagcattcc ggcggcctcg gtgagccatg
    11341 ccgcgtacga gcccctatca agcagcgcct tcgtgagggc ccccaggggc cggcggtgcc
    11401 gcgcacgcca cccggccgca tggcgcaggc cggccacggg tgagcgccgc agcagaccgt
    11461 gcacatacga aggcggcgac tggatgacct ggtccccgcc gaaaccggac aaccgcagcc
    11521 gggccccgtg cgcccgcatc tgcccggcca ggtatcgctg ctccacccgt gtacgcacga
    11581 tcgcggacgg ctcgtcgccc ggatccacgc attcgtccag cccgctgaac tgggcgggca
    11641 gatcagccga agcgaacacc agatgctcga cacccggaag gtgcccggcc gcccgggtgg
    11701 cgaagaggcg gtcttcgttg gtgggtgcgc ccgcgtccag tgtgacggcg accagccggg
    11761 cgcctgcctg tgcggccagg aagcacagcg aggtcgagtc catgccgccg gacaggtccg
    11821 cgcccaccac ctcgccgggt cgcacccgcg acgcgaccgc ccgctccagc gcctcgcgca
    11881 gcccggccgc ggcctcgtcc agcgggaggt cggccgcagg cggctgccac cagcgccggg
    11941 tgcgcacctc gccgccgggc gtcagttcca tcgctgtgcc gggcagtacg gcgtgcacgc
    12001 cgcgccacag cgcgtcccag ccgagcgggt gcgcgatggt gtcgccggtg agccgcagtg
    12061 ccaactgtgc ggtgtccagt tccgccgcgg tgagccgggc gaggacgcgg gcgtggctgg
    12121 cgcagaccgt gccgccgccg gcctccgccc ggtacaccct gcgctgcccg gagaagctgc
    12181 cccgcacgta cgtgtgtccc gcgacggatg cgaggaggtg gaagcagccg tgggcatcgc
    12241 gcagcaccgg ctcgatgtgc gcgctctggc tgatctgccg ggcccgtgcg gccagttcgg
    12301 cgggctgaag ggaacaggtc ccggcgaccg ccaggcgcac gtcaccgacg gcgcaggcag
    12361 ccagctcctc gtccggccag cagccggcca gccaaggacg gccggaagcg tgcggcacgg
    12421 tgcgcagcac ggcccggccg gcgaggtccc gcagacggcc gaggagacca ggtgccagat
    12481 cccggtcggg aaggacaacg aaccagtagg ccggcgtggc ggccatcgac atctccagtt
    12541 tgggggacaa gtgagtgcgg acgacatgac accgggtgcc ggtccggtcc tcgcggccca
    12601 ggccggcacc cgccgggatc gtcagagcca gaggccgacc gggtagtcgg gccagtcccc
    12661 gaactcgccc tgggtcagct cggcgtactg cccgacctcc gccagcagcg gcggctcgta
    12721 cacatccgtg gtctcaaagc cctgcagcgt ctcctgcacg gtgatcacct ccatccatgt
    12781 gaagacggaa cgtccgcctc ccgtaaggaa gttagacaga cccgcgcgcc gcacaggcag
    12841 caacgccggg ccaatccacc cgcaggaggg aagcaggtcg acggcccggc atcacgcgcc
    12901 gggcgtgcac caccgcctgc cctgcccgcg cctgcccggt cccactcctc accggctttc
    12961 gacacgatgt cgtcggcctg ctcgtgtccg atcccgacgg cggccagggc ctggaagacc
    13021 gtgaaccgcg ccgccgtggt ctcgtgctgg tggtggcgat acgggccagc tcctggcggg
    13081 agcttccccg tgatcttgga cactcatcgg ttatgccgcg agggcgtgtc ggtgccgctg
    13141 cctggtctcg gctggcgtga ggtagccgaa ggtcttgtgc ttgcgcaggc ggcggcggtt
    13201 gtagaaggtc tcgatgaagg cgaagacctc ggcgcgggcg gcggcccggt cgggccatat
    13261 gcgggtgccg atctcttcct tgagcagagc ccagaagctc tctgcggcgg cgttgtcgaa
    13321 gcatgatccg gtccgcccgc agctgctccg tggccccaac tcccgtacat gggcacggaa
    13381 ttgagccgag gcgtacccgc tgccgcgatc actgtggacc acgcagccgg actctggacc
    13441 gcctcggccg tgggccatgt cgagggcgtc gacgacgagc tcgcgcggtg gtggtcggcc
    13501 atggcatgac cgaccacttc acgggtagcc aggtccagcc ggcacgcgag gtagagccag
    13561 ccctcggcgg tgggcaggta agtgatatcg ccgaccagct tggtcccggg ccgctcggcg
    13621 tgaaagttgc ggccgatcag gtccggggcc ggcgtcgcct tcttgtccgg ccgggtcagc
    13681 gagcggcgcc tgcgccgggt gacgcctcgg atgtcacgct cgcgcatcac gcgggcgatg
    13741 cgcttgcggt tcacccgccg tcaaggggcg cagattccgc tgaacagtgt tggtcccgcc
    13801 ctgttcgtgc tcctggaagt aggcacggaa gaagcagttc agtgtggctg tgtcgactga
    13861 ggtgaagtcc tcttcgaacc cctgtgccgt catccactgg tccagcgcac ggaccgcctt
    13921 gctgtacgcc gtgacggtct tctcctggta gggccgaccg tgcttgttgt tggtcgcccg
    13981 gaggtgcgtg gcgtagtcct gagctgtgcc ctgcctgacc tctgacgtgt ccgggtcagt
    14041 ggggaggagt cggagcgctg cgcccctggt ggttccctga gacgccctga gaggtgactt
    14101 cttggcctgt gccgacacgg ggtgactccc tggtgtccgg gctaggcaag gtgcagtccg
    14161 ttaggcgcct tacctaaccg agtctggtag gtaagtcacg cggctttcga tgatccaact
    14221 gacctataca tgcaggtcag agactcaatg gcgcccccgg caggactcga acctgcggcc
    14281 aagcgcttag aaggcgcctg ctctatccac tgagctacgg gggccgggtg tggtggcctg
    14341 tggtgctggt gcccgggtgc gggcggggct gtgaccttgc cggggacaag gatagagctc
    14401 ctgggtcctt gtgcttcgcg cttcgccttc gtggctcgat gtggaggctc gtggaggttc
    14461 ggtgaagcgg tcccgataat cgcaggcagg tacgaatcgt gcatcgcttt tggcgcctcg
    14521 cgccccgggt gttgtgcact cgttatgcct gcgccccagt cgtcccttcc gccccgtgtg
    14581 tccgatcggc gcgcagacag gcccatatgc tttagaaagc ctccaaaatt gggcattctt
    14641 cgcatgtggt gaccttggac gtacggcccc agctgctcga cgcactctcc gccctgcgcg
    14701 accgtgtcgc cgccgcacgc ttcccgctgc ccctggcggg ggctccacgc gcgcgtgcca
    14761 accgcgacga gctgatcgca caactcgacg actatctcgt gccccggttg aggcaacccg
    14821 aagcacccct gctcgccgtg atcggaggat cgaccggggc aggcaagtcg acgctggtca
    14881 actcccttgt ggggcggcgg gtcagccagg ccggggtgct ccggcccacg acgcgtactc
    14941 cggtgctcgt ctgccatccg gaggaccatc actggttcag cgggatgcgg gtactgcccg
    15001 acctcacgcg cgtgtggatg ccccggcagg acgtcgacga cgatccgctg ctgtcggcgg
    15061 aggacgacct gcgtgtcctg cgcatcgaga ccgtcgacac ccttccccgg gggctcgcgc
    15121 tgctcgacgc gcccgacatc gactccctgg tggccgacaa ccgggtgctc gccgccgaac
    15181 tcatgtgcgc ggccgacatc tgggtcatgg tcaccacggc ggcacggtac gccgacgcgg
    15241 tgccgtggca tctgctgcgt accgccaagg agcatgacgc caccctcgtc accgtgctcg
    15301 accgggtgcc ccaccaggtg gtggccgagg tgtcgcgcca gttcggcgcg ctcctcgcca
    15361 aggcgggact cggcgacgta ccccgcttca ccgtgcccga gctgcccgag tcggcatggg
    15421 gcgggggact gcttccggcc accgccgtgg cacccctgcg tgcctggctg gcccagcagg
    15481 cacaggaccc gggcgcccgg cagcaggtga tggcgcgcac ggcgtacggg gtgctcgact
    15541 cgctgaagtc acggatgccc gagctcgccg gcgcggccgc ggcccagtac gccgccgcgc
    15601 tgcggctcac cgcggccgtc gacggggcgt acgacagcga gtacacgcgc ctgcggggcc
    15661 ggctgcaggc gggggccgtc ctcgccgggg acgcgctcaa gcggtggcgc agctacccgc
    15721 tggactgcag cgccggtgaa ctgctcgacg cgttggccga gagcctggcc gcactcctgc
    15781 tgtgtgccgt caccgcggcc gacgagcgcg tcgacgaggc ctggcggcgc gaacccgccg
    15841 cgggcgcccc cggcctgacg gaccgcgatc cgacgttgga gagcgccgag caccgcatcg
    15901 ggatggcggt acggcgctgg cggcgggtcc ttgaggagca tgccgaggac gaagtgcgcg
    15961 ccctggagaa gagcgtcgca ccggaccccg aagtggtggc cgcgctggtc gccaccgcgc
    16021 tcctgggcgg ccggcgggcg cggtcggcgg gcgaggggct cgccgagcgg atcggcgccc
    16081 acggcgcgct gcggctgcgc gacaagggtg gccggctgct caccgactac ctcgacaagg
    16141 cgctgcacga cgaacgggag cggcggctcg ccccgctcga cgccctcgac gtacaccccg
    16201 aaccccaggc cgaactcatc gccgcgctgt cggtactgca gaaggagagg tgaccgcggt
    16261 gaccgccgtc acggaccaca cggatcactc cgaccagccg ggagacgacg agggacggga
    16321 gggtgaagga cgggagggcg aggggcgaca ggaacgtggg cacgcacgcg tggaggacga
    16381 ttccgtgacc gaccggagaa acgcttacaa gaacgcccac aaggaggacc ccggcgggga
    16441 ggccgtccgc aaggagaagg gcgattcagg gcgcgtgcgt acggagacgg gtggcggcgc
    16501 cgagtccggt tccggctccg gtgctggtgc tggtcctggt gccggcggcg gctccgtgga
    16561 ggccgctgtc ggcgaggacg aggccgtcgg cagtggcatg gacgctgtgg acgccacgga
    16621 ctcggcgggc gcctgggacg acgggctgat cgcgcggcgc gtgtccgtca cggccgaggg
    16681 gcagaccagg gccgtacagg agatcgtcgt ggacaacagg tcccccgcgg tgactcccct
    16741 cgcgtacgac gggccgctac ggtcccgcct cgacgcgctg cgcgaactcg tggggctctc
    16801 ccgtacgcgg ctcgacaacc ggaccctcgc cgaggcggga cgcgtcctgg acgaggccgc
    16861 ggcgcggcgc aggctctccg ggcagcacac cgtcgtcgcc atcgcgggag ccaccggaag
    16921 cggcaagtcg cagctcttca acgcgctcgc cggagtggcc atctcggaga ccggggtacg
    16981 caggccgacc accgccgccc ccatcgcgtg cagctggagc gacggcgcgg ccggactcat
    17041 cgaccggctc ggtgtccccg ggcggctgcg ccgcaggccg ctgcagagcg ccgaggccga
    17101 ggcgcagttg cgcgggctcg tcctggtgga cctgcccgac cacgactcgg cggccctcca
    17161 gcaccgggaa cacgtggacc ggatgctggc gctcgtggac gccgtcatct gggtcgtcga
    17221 cccggagaag tacgccgacg cggtgctcca cgagcgctat ctgcggccca tggcgggcca
    17281 cgcggaagtc accttcgtgg tcctcaacca gatcgaccgg ctgcccggag aggccgccga
    17341 ccaggtcctc gacgaccttc ggcggctgct cgacgacgac gggatcgccc tcggcgagta
    17401 cggcgagccg ggcgcgaccg ttctcgcgct gtccgcgctc accggagagg gcatcggcga
    17461 actgcgcgag gcgctcggtc acttcgtggc cgagcggggc gccgcggccc gccggatctc
    17521 cgccgacgtg gacgcggccg cggtacgcct gtggcccgtc tacgccaacc ggcggcaggc
    17581 cgggctcagc gaggaggcgc gcgacgagtt cgccgaccgc ctcgccgacg cggtgggtgc
    17641 cacggcggcg ggcgaggcgg ccgagcgcgc gtggcgccgc aacgcgggcc gcgcgtgcgg
    17701 tacgccctgg ctgcggttgt ggcgctggta ccaggaccgg cgcgagcccc cgaccgggcg
    17761 cctctccgtc cggccgcacg acgaggaggc caccgcacgg cagcgcgtcg agcaggcggt
    17821 gcgcacggtg gccgagcggg cggccgacgg gctgccttcg ccctgggcgc aggcggtgcg
    17881 cgaggcggcc gtacgcgggt cgcaggggct gtgcgaggca ctggacgaac tggccgtacg
    17941 ggccggtgca ccggtcggac ggccgccgcg gccgggctgg tggccggctg ccgtactcgc
    18001 gcaggcggcc atgaccgtcc ttcaggtcgt cggcgggctg tggctggcgg ggcaggtcat
    18061 cggtttcatg tcgccgaacc tcggcgtgcc cgtgctgctg atggtcatcg gcatcgtggg
    18121 cggcccgggc gtcgagtggg cctgcaaact ggccgcgagc gggcccgcgc gacggtacgg
    18181 gctcgacgcg gaacggagat tgcgggaggc ggcggcggga tgcggccggg cccgggtcct
    18241 cgatccggtg gcggcggagc tgctgcggta tcgggaggtg cgggggcagt tcctgcgggc
    18301 cacgggggtc gacgccccgg tgggttgagg tcccgcaggg tggagcaacg cgagccggct
    18361 gcgggctggg ctgggacgag gggggcggaa gtcctcgttc gggtggcgga gttgtccaca
    18421 acggggtggt ggcccacagc gctcagcggg atcgggccgg ccgaggcagt ctgaggtcgt
    18481 ggcgatcgcg acgtgaccgc gacgtgatcg ccacgccaga tggacagtga caggcaggca
    18541 ggcaggcagg cagacgcagc cgtgcgggac gggcccgtac gtgtgggcaa gggagggctt
    18601 ccgcgatgaa cgagacgatg gtgtgcgtgg tggggaacgt ggctacgcag ccggtgttcc
    18661 gagagacggc ggcaggcgcg tcggcgaggt tccggctggc ggtcacgcag cggtactggg
    18721 accgcgagaa gaacgcctgg agggacgggc acaccaactt cttcacggtg tgggccaatc
    18781 gggcgctcgc gtcgaatgtg caagcgtccg tggcactggg cgaaccgctg gtggtgcgag
    18841 gcaggctgaa ggtccgctct gagcagcgcg acggacagtc gtgggcgggc gcggacatcg
    18901 aggcatcggc gatcgggcac gatctggcgc gcggcacggc ggcgttccgg aggacgctca
    18961 ggggtgatca ggcctctgat cagacgtctg acggagcgtc ggagcaagct cctgatctgg
    19021 cctccggtca ggcatcgggc acaccggccc ggccggagcc cagctgggag acggagccga
    19081 cggatcaggc cgatgaggcg gctcgacagg ggcaggagcc ggcattggcg acgtgaccag
    19141 aggtgctggt tccacggtct ggccgaagtg cggcttatcg gcggatgcaa ccggaagagt
    19201 cccggtggat ttgtcgatat gcccagctcg caaccggtcc tggcgataac gattccgagt
    19261 cggatcactc atcggatgac atgaccgggg agggaggtgc gccccgtcct taggatgccg
    19321 ggcatagctc tcggggcttc tgattccgct ggtgggaccg taacccccca ggtcaacggg
    19381 tcccgctcga aagggaattc tgtgctttct tcgttctctg cgccgtccgt gcacgggcga
    19441 ggtgccgctg ccgctcgcct ggccgcggtg gcgctcgtgt ccggactcgt cgccgtgagc
    19501 gccgcgacca ccgccggtgc ggccgtcgcg gacgaactcc ccctgagcca gggcggggcg
    19561 accgccacca taggtgggtt gaaggcgtct ggtccggctg tcatccatga ggacggcggg
    19621 gacaagcagg tctcggcggg cctgttcgag atgtccgtcg acaacggcgg cactctgcag
    19681 acctactgcg tggacatcta cagcccgacg cagaaggacg ccaagtacca ggaaaccccc
    19741 tggagcggta cgtcgctgaa cgagaacccc gacgcgggcc ggatccgctg gatcctgcgg
    19801 aactcctacc cgcaggtcaa cgacctcgcc gcgctggccg cgaaggcggg cgcgagcggc
    19861 ctcacggagc aggacgcggc ggcgggtacg caggtggcga tctggcggta ctcggacggc
    19921 gccgacgtgg acgccgtgga cccgcaggcg gagaagctcg ccgactacct gcagcgcagc
    19981 gcacgcgacc tcgcggaacc ggcggcttcc ctgagcctgg atccgcccgc ggtctccggc
    20041 caccccggcg aactgctcgg cccggtcacc gtgcgcacca acgcggacgg ggtgacggtg
    20101 acgccgcccg ccgacgccac gagcggggtc aggatcgtcg gccgggacgg caaggagatc
    20161 acgtccgcgg tcgacggcgg cgagctgtac ttcgacgtac ccgaggacgc cgcggacggt
    20221 tcggtggcgc tgacggtgca ggcctcgacc actgtgccgg tcgggcgggc cttcgcctcg
    20281 gagaccagga gccagaccca gatcctggcc ggttccagcg agtcgacggt ctccgcggcg
    20341 gcgaccgcga actgggccgg ttccggggcg atacccgcgc tgtcggccga gaagaactgc
    20401 gcagagggcg gcctggacat cacggcggtc aacgagggtg acgaggcgtt caccttcgag
    20461 ctgatgggct ccgagcacac cgtcgaggcg ggtacgtcac ggaccgtgac ggtcccgctg
    20521 caggaggacc agacgtacga cgtcacggtc gaggggccgg gcggctacga gaagcggttc
    20581 cagggcgtgc tcgactgccg gacacagagc ggcgtcggcg gcgagacggt ccagacgctg
    20641 aacgagccca gccccgccac ggtgggcggt acctccgccg cgaccaccga cctcgccgag
    20701 accggcacgt cgagtgccac cccggtgata gccgggattg cgatcggcct ggtcctgatc
    20761 ggcggcgccg cggtgctctt cgtccgcaag aggaagaccc cgacgcagga ctgacgtgac
    20821 gcggtgcgtg cgacagcctc ggactccatg gactccacgg actccacggc gatacggcag
    20881 cctccacgcg acgatctcct ctcccggatg gagggcgagg agatcggagt gatggacgcg
    20941 atgggggcgg tgggaagcga tggaggcact gccggccggg cgcggcgggt gacgctcagg
    21001 ccgaggagag ctgactggtg atctccttct cccaagcggt ctgcagcgcg gagttgttga
    21061 gtgaggcctc ccactcctcg cgcgtctgct tgtgctggga cggaccggcc ttgaggacga
    21121 tgagcatcgc acgtgccgat tcacggatgt cgtcggcaac gttgctgccc acgggaacgt
    21181 ctggcccggc tgcgagtgca tagagtttct gagccatgaa gtggcgctcg ccctgttgga
    21241 cggacttcgt caccttgaag aactccttca acgcgtcgcg ccgttctgcg ggtgcgggtg
    21301 cgggtgcgga cgcgggtgtg ggtgactcgg ccctctccgt cccggagtcg tcctgagccg
    21361 atgtgggccg ggcccagcgg tcgggatgcc gcgccgcgac ataccgattg ctgccggccc
    21421 tggctccctt gtagagagcg ttgccgagca ggagggccgc tgccacgccg gccacggcgg
    21481 gtgctgccgg accgctgagc gcaccggcgg caccagcgat cgccaggccg ccgccggcgg
    21541 cacgcaccgt gtttcccccg aggctggtga tgcgcttgcc caacttggtg tgctgcttgt
    21601 gccgtgcgta ctggcctatg tgggcgagct cggcctccag caggtggttg agctcaagaa
    21661 tttggttccg cagcgccgca acggccgttt cctcgtccgc cgaggggccg cccgcttgct
    21721 cccgcggggc ctcggcctgg gccagccgct gccgcacctg ccccagtcgg tcgagtacgt
    21781 cctggagccg gccctcgttc gcgggggcct cgccggacgc ttcttccacc atttccttga
    21841 gcgcgcggtt cttgttgtag gtgctccaga cgacagggac ctcacggatg gctatcagcg
    21901 tggaatagaa cacgctggca ccgccggtca cctctccgag agcaggcact cctgccagct
    21961 ggccggcgtt tcgcaccgcg gcgttggcca tgccgctgat gtcgccgacg accatgctgg
    22021 agttctgcgc cacgccgaga ggcttcccct tccagtcctt cctgggcttg tgggactccg
    22081 gacccgtgcc cttgcggtcc ttcctcgcgg ccagcagggc acgcccgtcg ttgaacgccc
    22141 ccaaggcatc ggtcaccgtg ttgatcccgg tgtcgacctg cgcgacgatc gcggtggcct
    22201 gtacctgacc ggtgtccgac gtggcctgcc cgtgcatccg gacaccgccc tccgtggggg
    22261 cgttgatgcg gttggccacc gtgtcgggct ggtcgaggac cttcttggtc ttgtcggcct
    22321 tggagggggt accgagaatt tgtttgatct tcccggtgac cttcttgagc gtcgtcccgg
    22381 cactgaacaa ccgccgcagc ctgcttcgcc gccgcttctc ttccggctgg ggctgctcct
    22441 gtgccgcggc ggcttcctcc tggcggcgct gttcctgtgc tgcggcggcc tcttcctgtt
    22501 ggcgcagctc ctcagcggca gcttcc
//
