LOCUS       NZ_AP023440            21098 bp    DNA     linear   CON 26-MAY-2024
DEFINITION  Streptomyces aurantiacus strain JCM 4677 chromosome.
ACCESSION   NZ_AP023440
VERSION     NZ_AP023440.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces aurantiacus
  ORGANISM  Streptomyces aurantiacus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 9428393)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye
            Genome Coverage                   :: 62X
            Sequencing Technology :: Illumina HiSeq X Ten; PacBio Sequel II
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014701115.1-RS_2024_05_26
            Annotation Date                   :: 05/26/2024 05:58:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,211
            CDSs (total)                      :: 8,122
            Genes (coding)                    :: 7,928
            CDSs (with protein)               :: 7,928
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 194
            CDSs (without protein)            :: 194
            Pseudo Genes (ambiguous residues) :: 0 of 194
            Pseudo Genes (frameshifted)       :: 69 of 194
            Pseudo Genes (incomplete)         :: 161 of 194
            Pseudo Genes (internal stop)      :: 17 of 194
            Pseudo Genes (multiple problems)  :: 48 of 194
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:48:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3182320
            Orig. end                         :: 3203418
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP023440.1.
            Genome sequencing and analysis were conducted under the Global
            Catalogue of Microorganisms (GCM) 10K type strain sequencing
            project (http://gctype.wdcm.org). The genomic data are also
            available at http://gctype.wdcm.org/sequencing/GCM10017557
            Annotated by DFAST v.1.2.7 (https://dfast.nig.ac.jp).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21098
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="18"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21098
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21098
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11098](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11098)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(340..354)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.38"
                     /tool="antismash"
     gene            556..765
                     /locus_tag="IGS71_RS12975"
                     /old_locus_tag="GCM10017557_26620"
     CDS             556..765
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019058292.1"
                     /locus_tag="IGS71_RS12975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_26620"
                     /product="YbdD/YjiX family protein"
                     /protein_id="WP_190850262.1"
                     /transl_table=11
                     /translation="MRSALHRAVRAARAVRWYVREFTDESAYDRYVAHVRKDRPDACVP
                     SRRAFERMRTDRQEEDPRQGFRCC"
     gene            900..1181
                     /locus_tag="IGS71_RS12980"
                     /old_locus_tag="GCM10017557_26640"
     CDS             900..1181
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992859.1"
                     /locus_tag="IGS71_RS12980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_26640"
                     /product="DUF3311 domain-containing protein"
                     /protein_id="WP_190850263.1"
                     /transl_table=11
                     /translation="MSETPDAPRAPEGDPPVVTPVRVVIALCLIAPFVALLWVGSYAKV
                     DPTFIGIPFFYWYQMLWVVISTVLTMTAYALWNRDQRARKSQNGGASA"
     gene            1178..2806
                     /locus_tag="IGS71_RS12985"
                     /old_locus_tag="GCM10017557_26650"
     CDS             1178..2806
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674905.1"
                     /locus_tag="IGS71_RS12985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_26650"
                     /product="sodium:solute symporter family protein"
                     /protein_id="WP_190850264.1"
                     /transl_table=11
                     /translation="MNDGVNGVALAVFIFFFLAVTVMGFLASRWRRAANEQTLDEWGLG
                     GRSFGTWVTWFLLGGDLYTAYTFVAVPAAIYAAGAAGFFAVPYTILVYPLIFTFLPRLW
                     SVSHKHGYVTTSDFVRGRFGSKGLSLAVAVTGILATMPYIALQLVGIQAVLDVMGVGGG
                     EDTNWFVKDLPLLIAFAVLAAYTYSSGLRAPALIAFVKDTLIYIVITVAIIYIPIKLGG
                     FDEIFAKAGEAYSQTNPATGAPRGALAPGEAGQWTYATLALGSALALFMYPHSITATLS
                     SRSREVIRRNTTILPLYSLMLGLLALLGFMAIAAGVKVDNGQLAIPQLFENMFPDWFAG
                     VAFAAIGIGALVPAAIMSIAAANLFTRNIYKDFIKPDATPAQETKVSKLVSLLVKVGAL
                     VFVLTMDKTVAINFQLLGGIWILQTFPALVGGLFTRWFHRWALLAGWAVGMVYGTVAAY
                     GVASPSQKHFGGSSKEIPGIGEIGYIGLTAIVLNVIVTVVLTFVLRALKAPDGVDETSA
                     EDYTADAGDKGVQVELPPATAGAGH"
     misc_feature    complement(2855..2870)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.86"
                     /tool="antismash"
     gene            2868..3392
                     /locus_tag="IGS71_RS12990"
                     /old_locus_tag="GCM10017557_26660"
     CDS             2868..3392
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326961.1"
                     /locus_tag="IGS71_RS12990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_26660"
                     /product="N-acetyltransferase"
                     /protein_id="WP_190850265.1"
                     /transl_table=11
                     /translation="MDIVIGRAEPGEYAALGEITAQAYLGDGLLDFRESEEYLGELRNV
                     AKRATAAEVLVAVEAGAGSPRGRLLGGVTFVPSGGPMAEIAREGEAEIRMLAVAKEARG
                     RGVGASLVCACVDRARATDGCAGLVLSTQRTMHSAHRIYERLGFSRDPARDWNPVPDLD
                     DIMLLTYTLTL"
     misc_feature    3452..3466
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: strong, score: 25.49"
                     /tool="antismash"
     regulatory      3477..3654
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    3483..3497
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.21"
                     /tool="antismash"
     misc_feature    complement(3600..3613)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.81"
                     /tool="antismash"
     gene            3791..6280
                     /locus_tag="IGS71_RS12995"
                     /old_locus_tag="GCM10017557_26670"
     CDS             3791..6280
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010984456.1"
                     /locus_tag="IGS71_RS12995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_26670"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_190850266.1"
                     /transl_table=11
                     /translation="MTIAPADPVSATAARDQQEHQQEHQQEHLRDRAEADGPGTALLRI
                     LTDFSADLPGAEPGKVAAAALRGRSAAADEPELRELATEAAAGLISEDPVYSKLAARLL
                     TVGIAAEAASQGVRSFSESVAVGHREGLIADRTAEFVRVHAARLDALVDASSAEGADDR
                     FGYFGLRTLHSRYLLRHPITRAVIETPQHFMLRVAAGLAEDDTVRAVDEVASLYRLMSH
                     LDYLPSSPTLFNSGTRHPQMSSCYLLDSPLDELDSIYDRYQQVARLSKHAGGIGLSYSR
                     IRSRGSLIRGTNGHSNGVVPFLKTLDASVAAVNQGGRRKGAAAVYLETWHSDIEEFLEL
                     RDNTGEDARRTHNLNLAHWIPDEFMRRVDEDRVWSLFSPSDVPELVDLWGEEFDAAYRA
                     AEAAGLAKRTVPARDLYGRMMRTLAQTGNGWLTFKDAANRTANQTALPGHTVHSSNLCT
                     EILEVTDDGETAVCNLGSVNLAAFVDADSRDTDTDTGSGSGDIDWERLDATVRTAVTFL
                     DRVVDINFYPTEQAGRSNSRWRPVGLGVMGLQDVFFKLRLPFDSPQARALSTRIAERIM
                     LAAYEASADLAERSGPLPAWEKTRTAQGVLHPDHYDVELNWPERWAALRARIASVGTRN
                     SLLLAIAPTATIASIAGVYECIEPQVSNLFKRETLSGEFLQVNTYLVAELKKLGVWDAR
                     TREALRESGGSVRDFSWVPQDVRDLYRTAWEIPQRGLIDMAAARTPFLDQAQSLNLFLE
                     TPTIGKLSSMYAYAWKSGLKTTYYLRSRPATRIARAAQAQAQPPSRSEKALPVQRAADP
                     DAVACSLENPESCEACQ"
     gene            6394..7350
                     /locus_tag="IGS71_RS13000"
                     /old_locus_tag="GCM10017557_26680"
     CDS             6394..7350
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010047584.1"
                     /locus_tag="IGS71_RS13000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_26680"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_246596748.1"
                     /transl_table=11
                     /translation="MRYPDFYERYRDAIKNTWTVEEVDLHSDVTDLAKLSPGEQHMIGR
                     LVAFFATGDSIVSNNLVLTLYKHINSPEARLYLSRQLFEEAVHVQFYLTLLDTYLPDPA
                     DRAAAFDAVESIPSIREKAEFCFKWMDSVEKLDRLETKADRRRFLLNLICFAACIEGLF
                     FYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMHMSFAFEVVDTVRKEEPDLFDDELRQ
                     QVTDMLREAVEAELQFGRDLCGEGLPGMNTESMRQYLECVADQRLQRLGLAPVYGSENP
                     FSFMELQGVQELTNFFERRASAYQVAVEGTVDLDEDF"
     gene            complement(7263..7532)
                     /locus_tag="IGS71_RS13005"
                     /old_locus_tag="GCM10017557_26690"
     CDS             complement(7263..7532)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992854.1"
                     /locus_tag="IGS71_RS13005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_26690"
                     /product="hypothetical protein"
                     /protein_id="WP_079103503.1"
                     /transl_table=11
                     /translation="MVSMNTTQLEGLIGMLAVLGILVLLVLPSVYGIVRDRRIDRQLRE
                     AEHVREAEREHGRRQDQKSSSRSTVPSTATWYAEARRSKKLVSS"
     gene            7617..8582
                     /locus_tag="IGS71_RS13010"
                     /old_locus_tag="GCM10017557_26700"
     CDS             7617..8582
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657912.1"
                     /locus_tag="IGS71_RS13010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_26700"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_190850268.1"
                     /transl_table=11
                     /translation="MLTNVAAILLDGAHPFELGVVCEVFGLDRSDDGLPVYDFAVASAE
                     GPDLATHVPGFTLSTPYGLDRLEEADLIVVPAGSHYIGRTYPPELLDSLVRAADRGTKV
                     LSVCSGVFVLGAAGLLDGRRCAVHWRHAETLAKRHPRAKVEPDVLYVDEDPVITSAGTA
                     AGIDACLHIVRKEQGPEVANSIARRMVVPPHRDGGQAQYVARPLPRSQCDTVGEVLVWM
                     DRHLDEEVTVEQLATRAHMSPRTFARRFQQETGTTPYRWLLRQRVLLAQELLEATDETM
                     DFIADRAGFGTAAALRHQFVRSLGTTPHAYRRTFRGPQAA"
     gene            complement(8634..10004)
                     /locus_tag="IGS71_RS13015"
                     /old_locus_tag="GCM10017557_26710"
     CDS             complement(8634..10004)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010984461.1"
                     /locus_tag="IGS71_RS13015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_26710"
                     /product="cytochrome P450"
                     /protein_id="WP_190850269.1"
                     /sec_met_domain="p450 (E-value: 3e-67, bitscore: 226.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVESVRSAAHQAAELSVPPLAGGRVPGLGHGLKLVRDPLGFLTR
                     LRDEGDVVRLKLGPKTVYAVTTPALTGELALNPDFKIDGPLWESLEGLLGKEGVATANG
                     PRHRRQRRTIQPAFRLDIIPEYGPIMEEEAHGLAERWRPGETIDGTAESFRVAVRIAAR
                     CLLRGDFMDERAERLSIALATVFRGMYRRMVIPAGPFYRLPLPANRQFDRALADLHLLV
                     DEIVAERRTSGQKPDDLLTALLAAKDENDEPIGEQEIHDQVVAILTPGSETVASTIMWL
                     LQVLAEHPEHADRVREEVESVAGDRPVAFADVRKLSHTNNVVVEAMRLRPAVWILTRRA
                     VSETALGGYRIPAGADIVYSPYAIQRDARSYDGHLEFDPDRWLPERAKDVPKYAMSPFS
                     VGNRKCPSDHFSMAQLGLITAAVASRWRLEQVSESNDTTRVGITLRPHRLLLRAVPR"
     gene            complement(10001..11098)
                     /gene="cyc1"
                     /locus_tag="IGS71_RS13020"
                     /old_locus_tag="GCM10017557_26720"
     CDS             complement(10001..11098)
                     /EC_number="4.2.3.37"
                     /GO_function="GO:0052680 - epi-isozizaene synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyc1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009190552.1"
                     /locus_tag="IGS71_RS13020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_26720"
                     /product="epi-isozizaene synthase"
                     /protein_id="WP_190850270.1"
                     /sec_met_domain="T1TS (E-value: 1.6e-63, bitscore: 214.5,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAFSPSTTTKHTSALVPPALSLPVIETEFPRRLHPYWPKLQEKT
                     RDWLLEMRLMPAAKVEAYADGLCYTDLMAGYYIGAPDEVLQAIADYSAWFFVWDDRHDR
                     DVVHGRPAAWQRLRNRLHTALDSPKDHLYHQDPLVAGFADSVVRLYSFLGEGWNARFAG
                     HFHAVIEAYDREFRNRTSGTVPTVEEYLELRRNTFAHWIWLDLLEPSAEYELPATVREN
                     AAYRRAALLCQDFAAWYNDLCSLPKEIAGAEVHNLGISLIHHEGMRLEESVREVRRRVE
                     ECITEFLDVEKEVLRYAERIDKGIDNGSARDAELAAAVRACLCNMRNWFSSVYWFHHES
                     GRYMVDSWDDRSTPPYVNNEAAGEK"
     gene            complement(11473..12123)
                     /gene="def"
                     /locus_tag="IGS71_RS13025"
                     /old_locus_tag="GCM10017557_26730"
     CDS             complement(11473..12123)
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="IGS71_RS13025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_26730"
                     /product="peptide deformylase"
                     /protein_id="WP_190850271.1"
                     /transl_table=11
                     /translation="MAQQDTEQQHSGVLPVDDEGFVIDTENSAEREAAYRGRGTSRPIT
                     VVGNPVLQKECKDVTEFGDELARLVDDMFASQHIAEGVGLAANQIGVDLKVFVYDCPDD
                     EGKRHTGVICNPVLVELPAERRHLDESNEGCLSVPTAYAPLARPDYAEVTGQDEKGNPV
                     KVRGTGYFARCLQHETDHLYGYLYIDRLSKRERKDALRQMAENEPRYPIVAND"
     gene            complement(12353..13360)
                     /locus_tag="IGS71_RS13030"
                     /old_locus_tag="GCM10017557_26750"
     CDS             complement(12353..13360)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089486.1"
                     /locus_tag="IGS71_RS13030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_26750"
                     /product="hypothetical protein"
                     /protein_id="WP_055512858.1"
                     /transl_table=11
                     /translation="MRIFGKGRHRPSASWRQATDRAFTLIGDGRYEDAGALLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARAAGLRAVALLDRETGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLRVPGGASRPKAGAGAAASGEPVGMDLGSAAVRLSPEGEAEVVWGRRLDPA
                     RVEVLSIPLPSSGRRWGEVVLHDGVPHGERTTTAGHAYPVFDEIELWAPSPVPTWVVLL
                     EAETEDDRDALERLAADAGFAAEDWSSSVRLLCRMCSESRMPSDEGDGEHLDPHDHSEP
                     GHPGPLGHRTDGQLWVPERECGLAAPASLVRGLLDGWVADSPDSRDWRDLEEVC"
     gene            complement(13519..13908)
                     /locus_tag="IGS71_RS13035"
                     /old_locus_tag="GCM10017557_26760"
     CDS             complement(13519..13908)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007495794.1"
                     /locus_tag="IGS71_RS13035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_26760"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_055512861.1"
                     /transl_table=11
                     /translation="MSDTSPPHPLTEILTSLRDRVMGVSESVLSTADGLLVVADTDSSH
                     AESVAALAAATLGVGRRMADQAGVGALREVVARCGSGHVIVMAVGDRALLTVMGDDGLD
                     LAALQRESPATVERLSRALAADVAR"
     gene            complement(14305..15243)
                     /locus_tag="IGS71_RS13040"
                     /old_locus_tag="GCM10017557_26770"
     CDS             complement(14305..15243)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005480438.1"
                     /locus_tag="IGS71_RS13040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_26770"
                     /product="hypothetical protein"
                     /protein_id="WP_246596368.1"
                     /transl_table=11
                     /translation="MTTATAAARNLPALLQGLYEEGYSGTVRVSGSPGGTIHLRDGLIG
                     AVETPGAPTATSVLLTPGRIDDESWLAACAVERDTERLGAHLVATGLIGAAELEIVCTA
                     AVFDAAFAMAVGPPGSWTLGDPEPTLLTGSGVAPRRLTEETTRRIVRLSGPWGAPGELA
                     RIRPAPVPDAALRPGLSDRHRSVLSTVNGRRTARDMAFTLGRGLYAIMLDLTRLEAREL
                     IRWETGRAADGRPSTAPRVLPGRGAPDEPPTRPTPTGSAPKAAPLPKRTPGGASRPGPG
                     EAQAREGPPGQGPAGGRDAFPGGSSGGHGGL"
     gene            complement(15240..15605)
                     /locus_tag="IGS71_RS13045"
                     /old_locus_tag="GCM10017557_26780"
     CDS             complement(15240..15605)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136685.1"
                     /locus_tag="IGS71_RS13045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_26780"
                     /product="hypothetical protein"
                     /protein_id="WP_245702619.1"
                     /transl_table=11
                     /translation="MTTAVDASLVRLLDSPGITGLALVDAVTGLTYGVAGDADEAGDGA
                     ECAELAALIAERLGRAGAEGELESVITTSTHRHHLLLSVERPAGDPLLLTAGMDRERAN
                     LALATRSLGDRIAEVLV"
     misc_feature    15715..15731
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.93"
                     /tool="antismash"
     gene            15767..16132
                     /locus_tag="IGS71_RS13050"
                     /old_locus_tag="GCM10017557_26790"
     CDS             15767..16132
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013000814.1"
                     /locus_tag="IGS71_RS13050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_26790"
                     /product="hypothetical protein"
                     /protein_id="WP_190850272.1"
                     /transl_table=11
                     /translation="MNIETALKEAMSVDGAIGVALVDYESGMALGTLGGGPTLDLELAA
                     AGNTEVVRAKMRTLSTLSMDDTIEDILITLGKQYHLIRPLTSSGGTLFLYLALDRSRGN
                     LALARHSLKKIESGLEV"
     gene            complement(16385..16747)
                     /gene="rsrA"
                     /locus_tag="IGS71_RS13055"
                     /old_locus_tag="GCM10017557_26800"
     CDS             complement(16385..16747)
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014154163.1"
                     /locus_tag="IGS71_RS13055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_26800"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_246596369.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCSEVLDHLYEFLDHEMPDADCTKFEVHFEECSPCL
                     EKYGLEQAVKKLVKRCCGQDDVPTDLRAKVMGRIELIRSGQAVPEHEGSIHGAVVREGG
                     AREVTTADARGAAAEG"
     gene            complement(16744..17424)
                     /gene="sigR"
                     /locus_tag="IGS71_RS13060"
                     /old_locus_tag="GCM10017557_26810"
     CDS             complement(16744..17424)
                     /codon_start=1
                     /gene="sigR"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="IGS71_RS13060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_26810"
                     /product="RNA polymerase sigma factor SigR"
                     /protein_id="WP_190850273.1"
                     /transl_table=11
                     /translation="MGPVTGTDAGTENGQAEQPESTGSSESTAERNVRFERDALEFLDQ
                     MYSAALRMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINSYRKKQ
                     REPQRSAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKSALQAIPEEFRIAVY
                     LADVEGFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYAKDRGLVPAGAGESDGTK
                     GSGS"
     gene            complement(17703..18386)
                     /locus_tag="IGS71_RS13065"
                     /old_locus_tag="GCM10017557_26820"
     CDS             complement(17703..18386)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136689.1"
                     /locus_tag="IGS71_RS13065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_26820"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_190850274.1"
                     /transl_table=11
                     /translation="MTEIIETVETVETVETDAGPARVTWHRAKKAERAEKAEQKARLVL
                     AVSHGAGGGIEARDLRALAAGLPAHGVTVALVEQPWRVAGKKLAPAPKTLDVGWRGLWP
                     ALARPGLPVVAGGRSAGARVACRTAAELGAHAVLALSFPLHPPGRPEKSRADELLGAGV
                     PTLVVQGGNDPFGRPEEFPQGSYELVEVPYGDHGFAVPKRAPIDQDQALAVITAGVLTW
                     VSSLG"
     gene            complement(18451..19266)
                     /locus_tag="IGS71_RS13070"
                     /old_locus_tag="GCM10017557_26830"
     CDS             complement(18451..19266)
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="IGS71_RS13070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_26830"
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_190850275.1"
                     /transl_table=11
                     /translation="MCGRYAASRGPEDLAGIFEIEKWEPEEALDPDFNVAPTKEVYVVL
                     DRPVKDAPDPGPVRQLRRLKWGLIPSWSKTPEGGARMINARAETVHEKPSFRRAFTSRR
                     CVIPADGYYEWVTGTDERDLEVEGKKKRPRKQPYFVLPADGSVFAMAGLYEFWRDKTLP
                     DDHPRAWWVTCSVITTEAETSPLAVAPEEGPRSLADIHPRMPLMLTPDRWDAWLDPSRT
                     DVEDVRSLLAPPPEGLMRAYPVSTMVSNVRNNGPELLKELEGPEEGTLF"
     gene            19317..20039
                     /locus_tag="IGS71_RS13075"
                     /old_locus_tag="GCM10017557_26840"
     CDS             19317..20039
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992842.1"
                     /locus_tag="IGS71_RS13075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_26840"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_190850276.1"
                     /transl_table=11
                     /translation="MDSTAATSLATLWDEVFGSQPDPDTWVVVATLAAALAVIVPHPLW
                     RLARNAITIAHEGGHGLVALLTGRSLDGIRLHSDTSGLTVSRGKPTGLGMILTATAGYT
                     APPLLGLGGAALLAAGHITALLWLATLLLVAVLVMIRNAYGALTVLLTGGTFVVVSWLC
                     GPQVQAAFAYAVVWFLLLGGVRPAFELQAKRSRGGAGDSDADQLSRLTHVPAGLWLFLF
                     HAVSLCSLIGGGRWLLAL"
ORIGIN
        1 gcatcgtctg cggcctgtgg ggctacttcc tgtgggtggg cgtccacgaa ccgctcggcg
       61 ggatcaacca gctgttcccg atcttcggca tctccaacca gctcctcgcc gcggtcgccc
      121 tggcggtctg cacgaccctg ctggtgaagt ccgggcgcct caaatgggcc tggatcaccg
      181 gtattccgct cgtctgggac gccacggtca cgctgaccgc gagctggcag aaggtgttct
      241 ccggcgaccc gcgcgtgggc ttcttcaagc agcgctcgat ctaccacgac ggcatcgacc
      301 ggggcgaggt catcgcaccc gcaaagagca tggacgacat gcacacgatc gtcacgaact
      361 ccacggtcga cggcgtcctc acggcggttc tcgccctact catcgtgatc gtgatcgcgg
      421 acgcgacgcg ggtgtgcatc agacacgtac gccgtcccgc gctctccacg ctcagcgagg
      481 cgccgtacgt cgagtcgcgg atcgtcgcgc cggccgggct gatcgcgacc aaggaggaga
      541 aggaggaggc acgcgatgcg gtcggcgctg caccgggcgg ttagagcggc gagagcggtg
      601 cgttggtacg tacgggagtt caccgacgag tccgcgtacg accgttacgt cgcgcatgta
      661 cggaaggacc ggcccgatgc ctgcgtgccc tcgcggcgcg cgttcgagcg gatgcgcacg
      721 gaccgccagg aggaggatcc ccgacaggga ttccgctgct gttgagcgag aagcgaccac
      781 tgtcgggcgg gaagcgacac ggcacatccg ttatgcggac aggggttcca taaagcgaaa
      841 gcgtccctta gatttcctgc gcgttgcaca ggtgatcagt gaggggacgg agccgcggta
      901 tgtcagaaac gccggatgcg ccaagagcgc ccgaggggga tccgccggtg gtgacgccgg
      961 tccgggtggt gatcgccctc tgcctgatcg cgccgttcgt ggcgctgctc tgggtggggt
     1021 cgtacgcgaa ggtcgacccg accttcatcg gcatcccgtt cttctactgg taccagatgc
     1081 tgtgggtcgt catctcgacc gtgctcacga tgaccgcgta cgccctgtgg aaccgtgacc
     1141 agcgcgcccg caagtcgcag aacgggggcg cgtccgcatg aacgacggcg tgaacggcgt
     1201 ggcactcgcc gtcttcatct tcttcttcct ggccgtcacg gtcatgggtt tcctggcctc
     1261 gcgctggcgc cgggccgcca acgagcagac gctcgacgaa tggggcctgg gcggacggtc
     1321 gttcgggacc tgggtcacct ggttcctgct cggcggcgac ctctacacgg cttacacgtt
     1381 cgtggcggtc ccggcggcga tctacgcggc gggcgcggcc ggcttcttcg ccgtcccgta
     1441 cacgatcctg gtctaccccc tcatcttcac cttcctgccc cgcctgtggt cggtctcgca
     1501 caagcacggg tacgtgacga cgtcggactt cgtgcgcggg cgcttcggct cgaaggggct
     1561 gtcgctcgcg gtcgccgtca ccggcatcct cgcgacgatg ccgtacatcg ccctgcagct
     1621 ggtgggcatc caggccgtcc tcgacgtgat gggcgtcggc gggggtgagg acaccaactg
     1681 gttcgtcaag gacctgccgc tgctcatcgc cttcgcggtg ctggccgcgt acacgtactc
     1741 gtccgggctg cgcgcacccg ccctgatcgc gttcgtcaag gacacgctga tctacatcgt
     1801 catcacggtg gcgatcatct acatcccgat caaactgggc ggcttcgacg agatcttcgc
     1861 caaggccggc gaggcgtaca gccagaccaa cccggcgacc ggcgcgccac gcggcgccct
     1921 ggcaccgggc gaggcgggcc agtggacgta cgcgacgctc gcgctcggct ccgcgctggc
     1981 actcttcatg tacccgcact cgatcacggc gacgctgtcc agccgcagcc gtgaggtgat
     2041 ccggcgcaac accacgatcc tgccgctgta ctcgctgatg ctgggcctgc tcgcgctgct
     2101 cggcttcatg gcgatcgcgg ccggggtcaa ggtggacaac gggcagttgg cgattccgca
     2161 gctcttcgag aacatgttcc ccgactggtt cgcgggcgtg gccttcgcgg cgatcggtat
     2221 cggcgcgctc gtgccggcgg ccatcatgtc catcgcggcg gcgaacctgt tcacccgcaa
     2281 catctacaag gacttcatca aacccgacgc gacgcccgcc caggagacca aggtctccaa
     2341 gctggtctcg cttcttgtga aggtgggtgc gctggtcttc gtcctgacca tggacaagac
     2401 cgtggcgatc aacttccagc tgctcggcgg catctggatc ctgcagacct tcccggcgct
     2461 ggtcggcggc ctgttcaccc gctggttcca ccggtgggcg ctgctcgcgg gctgggcggt
     2521 cggcatggtg tacgggacgg tcgccgccta cggggtggcc tcgccttcgc agaagcactt
     2581 cggtggctcg tcgaaggaga ttcccgggat cggggagatc gggtacatcg gtctgacggc
     2641 gatcgtgctg aacgtgatcg tgacggtggt cctgaccttc gtgctgaggg cgctcaaggc
     2701 tcccgacggt gtcgacgaga cctctgccga ggactacacg gcggacgcgg gcgacaaggg
     2761 tgtccaggtg gagctgccgc cggcaacggc gggggctggg cactagggcc ctaagggctg
     2821 tcccaggtac gggacaggta gaggcggcaa gggcgagaat gacccgcatg gacatcgtga
     2881 tcggacgggc ggagcccggg gagtacgccg cgctgggaga gatcaccgcg caggcgtatc
     2941 tcggggacgg gctgctcgac ttcagggaga gcgaggagta cctcggtgaa ctgcggaacg
     3001 tggcgaagcg cgccaccgcc gccgaggtac tcgtggccgt ggaggccggg gcggggtcgc
     3061 cccggggccg gcttctcggc ggagtgacct tcgtgccgtc cggcggaccc atggccgaga
     3121 tcgcgcgcga gggcgaggcc gagatacgga tgctggcggt cgcgaaggag gcccgcggcc
     3181 ggggcgtcgg cgcctccctc gtatgcgcct gcgtcgaccg cgcacgggcc acggacggct
     3241 gtgcgggcct cgtgctgtcc acccagcgca ccatgcacag cgcccaccga atctacgagc
     3301 gcctcggctt cagtcgcgac cccgcccggg actggaaccc cgtcccggac ctggacgaca
     3361 tcatgctcct cacctacacg ttgacgctct gacacactcc gcgactcctc cggccgactc
     3421 ctccggccgc tcctcctccg gagccgacgc gacacaagat gtaggggtgc ttccgcagcc
     3481 cggcacaaga tgtatgctca agctcgctgt cgtcgcaggg gaatccggtg cgaatccgga
     3541 actgtcccgc aacggtgtac ttatacgcgt atgcccccat gcctgcacct ctggatgccc
     3601 gcatgcgcgt acaagagtca agtccgagga cctgccgaca gcgcgcccgg gccgccggtc
     3661 cgggcgcatg acgtccgggc ctcgtggaat gggccggtgg acgcggcgta ccgctgcgcg
     3721 cagcgtgtac ccccgtgtgc cccgaccccc cctccccgca ggccccgtgc cgagcgaggg
     3781 agagccccac gtgaccatcg cgccagccga tccggtctcc gccacagcgg cccgggacca
     3841 gcaggagcac cagcaggagc accagcagga gcacctgcgg gacagggccg aggccgacgg
     3901 gccgggaacc gcgttgctgc ggattctcac cgacttcagc gccgatctgc ccggcgccga
     3961 acccggcaag gtcgccgccg ccgcactgcg cggccggtcc gccgccgcgg acgagccgga
     4021 gctgcgcgag ctcgccacgg aggcggccgc ggggctcatc tccgaagacc cggtctactc
     4081 gaaactggcc gcgcgcctgc tgacggtcgg catcgccgcg gaggccgcct cgcagggcgt
     4141 gcgctccttc tccgagtcgg tcgccgtcgg ccaccgcgag ggcctgatcg ccgaccgcac
     4201 ggccgagttc gtacgcgtcc acgcggcccg gctcgacgcg ctggtcgacg cctcttccgc
     4261 cgagggcgcc gacgaccgct tcggctactt cggcctgcgc accctgcaca gccggtacct
     4321 cctgcggcac ccgatcacca gggccgtcat cgagacgccc cagcacttca tgctgcgcgt
     4381 cgccgccggc ctcgccgagg acgacacggt cagagcggtc gacgaagtgg cttccctgta
     4441 ccggctgatg agccacctcg actacctgcc ctcctccccc acgctcttca actccggtac
     4501 gcggcacccc cagatgtcgt cctgctacct cctcgactcc cccctggacg agctggactc
     4561 catctacgac cgctatcagc aggtggcccg tctctcgaag cacgcgggcg gcatcggtct
     4621 ctcgtactcc cgtatccgct cccgcggttc gctgatccgc ggcacgaacg ggcactcgaa
     4681 cggcgtcgtc ccgttcctga agaccctcga cgcctcggtc gccgcggtga atcagggcgg
     4741 ccggcgcaag ggcgcggccg cggtctacct ggagacctgg cactccgaca tcgaggagtt
     4801 cctcgaactg cgcgacaaca ccggtgagga cgcccggcgt acgcacaacc tgaacctcgc
     4861 gcactggatc ccggacgagt tcatgcgccg ggtggacgag gaccgcgtct ggtcgctgtt
     4921 ctcgccctcg gacgtgcccg agctggtcga cctgtggggc gaggagttcg atgccgcgta
     4981 ccgcgcggcg gaggccgccg ggctcgcgaa gcggaccgtc ccggcccgtg acctgtacgg
     5041 ccgcatgatg cgcaccctcg cgcagaccgg caacggctgg ctgaccttca aggacgccgc
     5101 caaccgcacg gccaaccaga cggcgctgcc cggccacacg gtccactcct cgaacctgtg
     5161 caccgagatc cttgaggtca cggacgacgg ggagaccgcc gtctgcaacc tcgggtcggt
     5221 caacctggcc gccttcgtgg acgccgactc ccgcgacacc gataccgaca cgggctccgg
     5281 ctccggcgac atcgactggg agcggctgga cgcgaccgtc cgtaccgccg tgaccttcct
     5341 cgaccgggtc gtcgacatca acttctaccc gaccgagcag gcgggccgct ccaactccag
     5401 gtggcgtccg gtgggtctgg gcgtgatggg gctgcaggac gtcttcttca agctgcggct
     5461 gccgttcgac tccccgcagg cacgggcgct ctccacccgg atcgccgagc ggatcatgct
     5521 cgccgcgtac gaggcctccg ccgacctcgc cgagcgcagc ggcccgttgc ccgcctggga
     5581 gaagacgcgt acggcccagg gtgtgctgca cccggaccac tacgacgtcg agctgaactg
     5641 gccggaacgc tgggcggccc tgcgggcgcg gatcgcctcc gtcggcacgc gcaactcgct
     5701 gctgctcgcg atcgccccca ccgccaccat cgcgtccatc gcgggcgtgt acgagtgcat
     5761 cgagccgcag gtctccaacc tgttcaagcg cgagaccctg tccggcgagt tcctccaggt
     5821 caacacctac ctggtggccg agttgaagaa gctcggcgtg tgggacgcgc ggacccggga
     5881 ggcgctgcgc gagtcgggcg gctcggtgcg ggacttcagc tgggtcccgc aggacgtgcg
     5941 cgacctgtac cgcacggcgt gggagatccc gcagcgcggc ctgatcgaca tggccgcggc
     6001 ccggaccccg ttcctggacc aggcccagtc gctgaacctg ttcctggaga cgccgaccat
     6061 cggcaagctc tcctcgatgt acgcgtacgc ctggaagtcg ggcctcaaga cgacgtacta
     6121 cctgcgctcg cgcccggcga cccgcatcgc ccgtgccgcc caggcccagg cccaaccccc
     6181 gtcccggtcc gagaaggccc ttcccgtcca gcgggccgcc gatcccgacg cggtcgcctg
     6241 ctcccttgag aaccccgagt cctgcgaggc ctgccagtaa tgacgaccac tcccgaaaag
     6301 accgagcgga tccagcacac cgaaaaagct cagcggaccg agaagaccgc gaagaacctt
     6361 ctcgatcccg gcttcgagct gaccctgcgt cccatgcgct acccggactt ctacgagcgc
     6421 taccgggacg cgatcaagaa cacctggacc gtcgaggagg tcgacctcca ctcggacgtc
     6481 accgacctgg cgaagctgtc accgggcgag cagcacatga tcggccggct ggtcgcgttc
     6541 ttcgcgacgg gcgactcgat cgtgtcgaac aacctggtgc tgacgctcta caagcacatc
     6601 aactcccccg aggcgcggct gtatctgagc cgccagctct tcgaggaggc cgtgcacgtc
     6661 cagttctatc tgacgctgct cgacacctat ctgcccgacc cggcggaccg ggcggcggcc
     6721 ttcgacgccg tcgagagcat cccgtccatc cgggagaagg ccgagttctg cttcaagtgg
     6781 atggactcgg tagaaaagct ggaccggctg gagacgaagg ccgaccggcg ccgcttcctg
     6841 ctgaacctca tctgcttcgc cgcgtgcatc gaggggctgt tcttctacgg tgccttcgcg
     6901 tacgtctact ggttccgcag ccggggcctg ctccacggtc tggcgaccgg caccaactgg
     6961 gtgttccgcg acgagacgat gcacatgtcc ttcgccttcg aggtggtcga caccgtccgc
     7021 aaggaggagc cggacctctt cgacgacgag ctgcggcagc aggtcaccga catgctccgg
     7081 gaggctgtcg aggccgagct gcagttcggc cgcgacctgt gcggtgaggg cctcccgggc
     7141 atgaacaccg aatcgatgcg gcagtacctg gagtgcgtgg ccgaccagcg cctgcagcgg
     7201 ctcggcctcg ccccggtgta cggctccgag aaccccttct cgttcatgga gctgcagggg
     7261 gttcaggagc tgaccaactt cttcgagcgc cgtgcctcgg cgtaccaggt ggcggtggag
     7321 ggaacggtcg acctcgacga ggacttctga tcctgccggc gaccgtgctc gcgctcggcc
     7381 tccctgacgt gctcggcctc cctgagctga cggtcgatgc gccggtcgcg cacgatgccg
     7441 tacaccgagg ggaggacgag caggacgagg attccgagga ctgcgagcat tccgatcagg
     7501 ccttccagct gtgttgtgtt catggacacc actgtcccgc cgaacggtcc tgaccgtgag
     7561 tggcagtact gccgcacacc ctcgatttcc tgccacatcc ggtgcacact ggcagcatgc
     7621 tgaccaacgt ggccgccatc ctgctcgacg gtgcgcatcc attcgaactc ggcgtcgtgt
     7681 gcgaggtgtt cggactcgac cgcagcgacg acggactgcc ggtgtacgac ttcgccgtcg
     7741 cctcggccga gggacccgac ctcgccacac acgtcccggg gttcacgctc tccaccccgt
     7801 acggtctcga ccggcttgag gaggccgacc tgatcgtcgt gcccgccggg agtcactaca
     7861 tcgggcgcac ctatccgccc gaactgctcg actccctcgt gcgggcggcc gaccggggca
     7921 ccaaggtgct cagcgtctgc tccggggtct tcgtgctcgg cgccgccggg ctgctcgacg
     7981 ggcggcgctg cgcggtccac tggcggcacg ccgagaccct ggccaagcgc catccgcgcg
     8041 cgaaggtcga accggacgtg ctgtacgtgg acgaggaccc ggtgatcacc tcggcgggca
     8101 ccgccgccgg catcgacgcc tgtctgcaca tcgtccgcaa ggagcagggc ccggaggtcg
     8161 ccaacagcat cgcgcgccgc atggtggtgc ctccgcaccg ggacggcggg caggcccagt
     8221 acgtcgcgcg gccgctgccg cgctcgcagt gcgacacggt cggcgaggtg ctcgtctgga
     8281 tggaccgcca cctcgacgag gaggtgaccg tcgaacagct cgccactcgc gcgcacatgt
     8341 ccccgcgcac gttcgcccgc cgcttccagc aggagacggg gaccaccccg taccgctggc
     8401 tgctgcggca acgggtgctg ctggcccagg agttgctgga ggccacggac gagacgatgg
     8461 acttcatcgc ggaccgcgcg gggttcggga ccgcggccgc gctgcgccat cagttcgtcc
     8521 gctcgctggg gacgaccccg cacgcgtacc ggcgcacgtt caggggacca caggccgcct
     8581 gaacgcgcgc cgcgcggtgg tcaccgagcg atcaccgagt catcgccgag tgatcaccgc
     8641 ggtacggccc tcagcagcag ccggtgcggt cgcagggtga tgccgacccg tgtggtgtcg
     8701 ttggactcgg acacctgttc aagacgccag cgtgaggcca ccgccgccgt gatgaggccg
     8761 agctgggcca tcgagaagtg gtcgctcggg cacttccggt tgcccacact gaaggggctc
     8821 atcgcgtact tcggtacgtc cttggcgcgt tccggaagcc agcggtcggg gtcgaactcc
     8881 agatgcccgt cgtacgaacg cgcatcgcgc tggatcgcgt acggactgta gacgatgtcg
     8941 gccccggccg gaatgcgata cccgccgagt gcggtttcgg acacggcccg gcgcgtcaat
     9001 atccatacgg cggggcgcag ccgcatggcc tcgacgacga cattgttcgt gtgggacagc
     9061 ttccgcacgt ccgcgaatgc gaccggacgg tcacccgcga ccgattcgac ctcttcgcgc
     9121 acccggtccg cgtgttccgg gtgttcggcg agtacctgta ggagccacat gatggtggag
     9181 gcgacggttt cgctgccggg ggtgagtatc gcgaccacct gatcgtgtat ctcctgttcc
     9241 ccgatgggct cgtcattctc gtccttcgct gccagcaatg ccgtcagcaa atcgtccggc
     9301 ttctgaccgg atgtgcggcg ttcggccacg atttcgtcga cgaggaggtg caaatcggcc
     9361 aaggcgcggt cgaattggcg attggccgga agcggcagcc gatagaacgg accggccggg
     9421 atcaccatgc ggcggtacat gccccggaac acggtggcga gcgcgatgct cagccgctcg
     9481 gcccgctcgt ccatgaagtc gccgcgcagc aggcagcggg cggcgatgcg gacggcgacg
     9541 cggaacgact ccgcggtgcc gtcgatcgtc tcgccgggcc gccagcgctc cgcgagaccg
     9601 tgtgcctcct cctccatgat cggcccgtac tcggggatga tgtccagccg gaacgcgggc
     9661 tggatcgtgc gccgctgacg ccggtgccgc ggcccgttgg cggtcgccac tccctccttg
     9721 ccgagcaggc cttcgaggga ctcccacagg gggccgtcga tcttgaaatc ggggttcagc
     9781 gccagttctc ccgtgagggc cggcgtcgtg accgcgtaca cggtcttggg gcccagcttc
     9841 agccggacga cgtcgccctc gtcgcgcagc cgggtgagga agcccagcgg gtcgcggacc
     9901 agtttcagac cgtgcccgag gccggggaca cggcccccgg cgaggggcgg gacggacagt
     9961 tctgccgctt ggtgtgcagc ggaccgtacg gactcgacgg tcatttctca cctgccgctt
    10021 cgttgttgac gtacgggggt gtggagcggt cgtcccagct gtcgaccatg taccgtcccg
    10081 actcgtggtg gaaccagtac acggagctga accagttccg catattgcac agacacgccc
    10141 gtacggcggc cgctagttca gcgtcccggg cggacccgtt gtcgatcccc ttgtcgatcc
    10201 tttccgcgta cctcagtacc tccttctcga cgtcgaggaa ttcggtgatg cattcctcga
    10261 cacgacgtct gacttctctg accgattcct caagccgcat tccctcgtga tgaatgagac
    10321 tgatgccgag attgtggacc tcggcgcccg ctatttcctt gggcagcgaa cacaggtcgt
    10381 tgtaccaggc ggcgaaatcc tggcacagca gagcggcccg ccggtacgcg gcgttctccc
    10441 gcacggtggc gggcagttcg tactccgcgc tcggttcgag caggtcgagc cagatccagt
    10501 gcgcgaaagt attccgccgc agttcgaggt attcctcgac ggtcggcacg gtgcccgacg
    10561 tacggttgcg gaattctcgg tcgtacgcct cgatgacggc gtggaagtgg cccgcgaacc
    10621 gcgcgttcca cccctcgccc aggaacgagt acagccgcac cacactgtcc gcgaaccccg
    10681 ctaccagggg gtcctggtgg tacagatggt ccttcgggga gtcgagtgcc gtgtgcagcc
    10741 ggttcctgag ccgctgccag gccgccggcc tgccgtggac gacgtcacgg tcgtggcggt
    10801 cgtcccagac gaagaaccac gcgctgtagt ccgctatcgc ctggaggacc tcgtcgggcg
    10861 cgccaatgta gtagcccgcc atgaggtcgg tgtagcagag accgtcggca tatgcctcga
    10921 ccttggccgc cggcatgagg cgcatttcca ggagccagtc cctggtcttc tcctggagct
    10981 tcggccaata cggatgaagt cgacggggaa actcggtctc gatcaccggg agagagagcg
    11041 ccggtggaac gagggccgag gtgtgcttcg ttgtggtgct cggtgagaaa gcaggcacga
    11101 acaaacccct ttcagccgcc tgttggcgcc acacccctcc cgcggtgccg ggcgtgcgcc
    11161 gttgcgtatc cccgccttcc cattcagcac cacaaccgac cgttctggga acggatttgc
    11221 ttcactcact accccaccgt gccgagaatc tccctatgtg tgactgaatt tggatcatta
    11281 agggcgcata ttagatcgaa cgtgcgacgc acagacgaac ggcgcctggt cggaagggaa
    11341 tccgaccagg cgccgtgggg agaaacgcac gcgccccggc tgtcgtgttc tgccacaggc
    11401 gttcacggac gttcatgaac gatcagacgt tcacggacgt ctacagagac gtccgcagag
    11461 gttcgcgggt gttcagtcgt tcgcgacgat ggggtaccgc ggttcgttct cggccatctg
    11521 gcgcagcgcg tccttgcgct cgcgcttcga gagccggtcg atgtagaggt acccgtacag
    11581 gtggtccgtc tcgtgctgga ggcagcgcgc gaagtaaccc gtgccgcgta ccttgaccgg
    11641 gttgcccttc tcgtcctgcc cggtgacctc ggcgtagtcg gggcgggcca gcggcgcgta
    11701 cgcggtcggc accgagaggc agccctcgtt gctctcgtcc aggtggcgcc gctcggcggg
    11761 cagctcgaca agcacggggt tgcagatcac tcccgtgtgc cgcttcccct cgtcgtccgg
    11821 gcagtcgtag acgaagacct tgaggtcgac gccgatctgg ttggcggcca ggcccacgcc
    11881 ctcggcgatg tgctggctgg cgaacatgtc gtcgaccagc cgggcgagct cgtcaccgaa
    11941 ctccgtgacg tccttgcact ccttctgcag caccgggttc ccgacgaccg tgatgggccg
    12001 ggaggttccg cgcccgcggt aggcggcctc gcgctccgcc gagttctcgg tgtcgatgac
    12061 gaagccctcg tcgtccacgg ggagcactcc ggagtgctgc tgctcagtgt cctgctgcgc
    12121 catgaccgac gtaagccttc ctcggaaaac agggggttgc aatgctcata cagggtacgg
    12181 ggcgcacccc gaccggaact cacacgctcc tgaagggggc gtgcttcaag gggcgcgggg
    12241 aactgcgcga ccggccacgg acgacccgcg gcccgcgtac caccgaggca cccccgacaa
    12301 ccccggcaac ccccacctga caggtctgtc aggcttgtca gacctgtcag acctaacaga
    12361 cctcttcaag atcccgccag tcccgggaat ccggactgtc ggcgacccac ccgtccaaca
    12421 gccccctcac caacgaggcg ggggccgcaa gcccgcactc gcgctccggc acccacagct
    12481 gcccgtcggt acggtgcccg aggggaccgg gatgccccgg ctcactgtgg tcgtgcgggt
    12541 cgagatgctc accgtcgccc tcgtcggacg gcatccgcga ctcggagcac atccggcaga
    12601 gcagccgcac ggaggacgac cagtcctcgg cggcgaaccc ggcgtcggcc gcgagccgct
    12661 ccagggcgtc ccggtcgtcc tcggtctccg cctccaggag cacgacccag gtgggcaccg
    12721 gcgagggcgc ccacagctcg atctcgtcga agacgggata ggcgtgcccg gcggtggtcg
    12781 tccgctcccc gtggggaact ccgtcgtgca ggacgacctc gccccagcgc cgcccggagg
    12841 acggcagcgg gatggagagg acctccacac gggcggggtc gagtcgccgc ccccacacga
    12901 cctcggcctc gccctcgggc gacagccgta cggccgcgct gcccaggtcc atgcccaccg
    12961 gctcaccgga ggcggcggcg cccgcgccgg ccttgggccg ggaggcaccg cccggcaccc
    13021 gcaggccgta cgcctgccag gcccgccggg ccagcggcca gtcctggagg gcggtcgccg
    13081 cgatgcccac gttccaccaa tcgggggccc cggtctcccg gtcgagcagg gccacggccc
    13141 gcagaccggc ggcccgcgcc tgctcccagt cgtgccggaa cttgtgcagc agcgcgaggt
    13201 tgaaccagga ctcggacagc cagggctcca ggtccgccgc acgtgtcagc agcgcccccg
    13261 cgtcctcgta ccggccgtcg ccgatcagtg tgaacgcacg gtcggtggcc tgccgccatg
    13321 aggcggaggg ccggtgccgc cccttgccga agatcctcac gattcccgcc tgccagttcg
    13381 ttgaagagcg tgcagcctcg ggctggactg tgccccctga tgtcctcttc ctcgcatcca
    13441 accacggacg gtcggacagg cgctcattac ccatgggtta cccacccggg ggcaaggtaa
    13501 gaccgtctct tcagcggctc accgggccac gtcggccgcg agcgcccggc tcaaccgctc
    13561 caccgtggcg ggcgactccc gttgcagcgc ggcgaggtcg aggccgtcgt cccccatgac
    13621 ggtcagcagc gcccggtcgc ccacggccat cacgatgacg tgccccgagc cgcacctcgc
    13681 caccacctcg cgcagcgcgc cgacaccggc ctggtcggcc atccggcggc ccacaccgag
    13741 ggtcgcggcg gcgagcgcgg cgacggactc ggcgtgcgag gagtccgtgt cggcgacgac
    13801 aaggaggccg tccgccgtgg acagaacgct ctcggagact cccatcaccc ggtcacgcag
    13861 agaggtcagg atctcggtga ggggatgggg cggcgacgtg tcgctcatgg cgctccttgc
    13921 tgcgtgcatg gatggtcgtg gtgcggtcgg agcggcgtca gtcgggatcc ggaatggctc
    13981 tcagaccccg gcggacccgg tgcagcatgt cgagggaggg ctgatcggcg gccaactgct
    14041 cggccgacag cacgggcaaa gcgaaggccg gcgccccgga ggacaaaggc gcgccccgta
    14101 cgggcagcgg cggcggtctg tgggctgtcg gggtaccggc agtcgcggct tcagcacgcg
    14161 cggcgccggc agtcgggata ccggcagtcg ggataccggc agtcgaagtg ctggacgcgg
    14221 cgcccgcacc cctgcccctg cccctgcccg cgcctctccc cctgccctgc cgaagacgct
    14281 tcgccgcccg acgtctgctg gaactcacaa gcccccgtgc cccccgctcg atcccccggg
    14341 aaaagcgtct cttccaccgg cgggcccctg ccccggcggg ccctcccgcg cctgggcctc
    14401 ccccggcccc ggccgcgagg ccccgccggg cgtacgtttc gggagcggcg cggccttcgg
    14461 ggccgacccg gtcggcgtgg gcctcgtcgg cggctcgtcc ggggcgccgc gtcccggcag
    14521 cacgcgcggt gcggtgctgg gccggccgtc cgccgccctg cccgtctccc accggatgag
    14581 ttcccgcgcc tccaggcggg tcagatccag catgatcgcg tacagcccgc gtccgagcgt
    14641 gaaggccatg tcccgtgcgg tgcggcgccc gttgacggtg ctcagtacgg accggtggcg
    14701 gtccgaaaga ccagggcgca gcgctgcgtc cggaaccggc gcgggccgta tccgggcgag
    14761 ctcccccggc gccccccacg ggccggagag ccgcacgatg cgccgcgtgg tctcctcggt
    14821 cagccgccgg ggcgcgacac ctgacccggt gagcaaggtg ggttccgggt cgcccagcgt
    14881 ccagcttccg ggcgggccga ccgccatggc gaaggccgcg tcgaacacgg cggcggtgca
    14941 cacgatctcc agctcggcgg cgccgatcag tccggtggcg accagatgcg cgcccagccg
    15001 ttccgtgtcg cgctccaccg cacaggcggc cagccagctc tcgtcgtcga tgcggccagg
    15061 ggtgagcagt accgaggtgg cggtcggggc gcccggtgtc tcgaccgcgc cgatcaggcc
    15121 gtccctcaga tgaatcgttc cgccggggga accggagacc cggacggtgc cgctgtagcc
    15181 ctcttcgtac aaaccctgga ggagcgcggg cagattgcgc gccgccgctg tggccgtcgt
    15241 catacgagca cctcggcgat ccggtcgccc agactccgcg tggcgagcgc caggttggcc
    15301 cgctcccggt ccatgcccgc ggtcagcagc aacgggtcgc cggccggccg ctcgacggag
    15361 agcagcagat gatggcggtg cgtgctggtg gtgatcacgc tctccaactc cccctcggcg
    15421 cccgcccgtc ccagccgttc ggcgatgagg gccgcgagtt cggcgcactc cgcgccgtcg
    15481 ccggcctcgt cggcgtctcc ggccaccccg taggtgagac cggtgaccgc gtcgaccagg
    15541 gcgaggccgg tgatcccggg ggagtcgagg agccggacca gggaggcgtc aacggccgtc
    15601 gtcatttccc cgttccccct tcacgtgttg acgtcgcaac actactttga gactcaactt
    15661 acgcaacaga caccatattt tgcgttttgt ggcgcactac tctcttgtgt tcgatcgtag
    15721 ttgtataagc aacgaccgga cagggtcacc gaggaactgg agcaacatga acatcgagac
    15781 cgcgctcaag gaagccatgt ccgtggacgg tgccatcggc gtcgccctcg tcgactacga
    15841 gagcggtatg gcgctcggca cgctcggcgg tggacccacg ctcgacctgg aactcgcggc
    15901 ggcgggcaac actgaagtgg tgcgcgcgaa gatgcggacg ctgtccacgc tgtccatgga
    15961 cgacaccatc gaggacatcc tgatcacgct gggcaagcag taccacctga tacgcccgct
    16021 cacctcaagc ggcggaacgc tcttcctgta cctcgcgctc gaccggagcc gcggcaacct
    16081 ggcgctggcc cggcacagcc tgaagaagat cgagagcgga ctggaggtct gacgccacgc
    16141 ccggacaccc gaacgccgga ccggggggaa ccggtccggc gtcggcacag cgggaacagg
    16201 cgccggcaca gcgggaaccg tccggccgtg aaacggtccg gtcagcgcgg ccggtcagcg
    16261 cggccggtca ctgacggccg tcgtgcggcg cccgatcgcc cggcaggggg aggcgggtgg
    16321 gagatgcggg tggggacgga agccttggat gcgcccgtcc cggccggcaa gaatccgggg
    16381 cgttctagcc ctcggcggcg gctccgcgcg cgtccgcggt ggtgacctct cgggcaccgc
    16441 cctcgcggac gacggccccg tggatactgc cctcgtgctc gggcacggcc tgccccgagc
    16501 ggatcagctc gatgcggccc atgaccttcg cccgcaggtc ggtcggcacg tcgtcctgac
    16561 cgcagcagcg cttgacgagc ttcttcaccg cctgctccag gccgtacttc tcaaggcacg
    16621 gtgagcactc ctcgaagtgc acctcgaact tggtgcagtc cgcatcgggc atctcgtggt
    16681 cgaggaactc gtagagatga tcgagtactt cactgcagtc cgtctcgtgc ggctctccgc
    16741 agctcatgag cccgagcctt tcgttccgtc cgactctccg gcgcccgccg ggaccagacc
    16801 gcggtccttg gcgtagtcct caagcatgcc gcgcaactga cggcgacccc tgtgcaggcg
    16861 ggacatcacc gtaccgatgg gtgtccccat gatgtccgcg atctccttgt acgcaaagcc
    16921 ctcgacgtcg gcgagataga cggcgatgcg gaattcctcg gggatcgcct gcagcgcgga
    16981 cttgacgtcc gagtcgggca ggtggtcgag cgcctgcgac tcggcggagc gcagacccgt
    17041 cgacatgtgc gactcggcac gcgccagctg ccagtcctcg atctcctcgg cggcggaccg
    17101 ctggggctcg cgctgcttct tgcgatacga gttgatgaag gtgttcgtga ggatcctgta
    17161 cagccacgcc ttgaggttgg tgccctcacg gaactggtgg aaggacgcgt acgccttggc
    17221 atacgtctcc tgcaccaggt cctcggcgtc ggccgggttc cgcgtcatgc gcagcgcggc
    17281 cgagtacatc tggtcgagga actccagcgc gtcccgctcg aagcgcacgt tgcgctcagc
    17341 ggtggactcg ctgctgcccg tgctctcggg ctgctccgcc tggccgtttt cggtccctgc
    17401 gtcggtccct gtgaccggac ccacctcctc cagagtctgg gcagggccga aaccggcccc
    17461 acctgcttcg gagaatagac gaccggtggt cacggcggct tgccgatccg gtccgcccgc
    17521 cgcccggaca ggagcggtct tcgccgcgtg cagcaccgac cactccaggt cagcggtgct
    17581 gccacgactc gggcagatgg tcgaacccat gcggcggact tcctctcgtg cgacgtctca
    17641 cagcacacct tccgtactgt ctgatccgca caacagtgct ccggggctca gcattcccag
    17701 ggtcacccga gtgacgagac ccacgtcagg acgccggccg tgatgaccgc cagggcctgg
    17761 tcctggtcga taggggcacg cttcggcacg gcgaagccat gatctccgta cggcacctcg
    17821 acgagctcgt acgagccctg cgggaactcc tcggggcgtc cgaacgggtc attgccgccc
    17881 tggacgacga gcgtgggcac cccggcgccg agcagttcgt ctgcgcggga cttctccggc
    17941 ctgcccggcg ggtggagcgg gaagctgagc gcgaggacgg cgtgggcgcc cagctctgcg
    18001 gccgtacggc aggcgacgcg ggctccggcg ctgcggccac ccgcgacgac ggggagcccg
    18061 ggcctcgcga gcgccggcca caggccccgc caccccacgt ccagcgtctt cggcgcgggc
    18121 gccagcttct tgcccgccac ccgccagggc tgttcgacga gggccacggt cactccgtgg
    18181 gcgggcagtc cggcggcgag tgcgcggagg tcgcgcgcct cgatcccgcc gccggcgcca
    18241 tggctgacgg ccagcaccag ccgcgccttc tgctcagcct tctcggccct ctcggccttc
    18301 ttcgcccggt gccaggtgac acgggccggg cccgcgtcgg tctccaccgt ctccaccgtc
    18361 tccaccgtct cgatgatctc cgtcacatgc gtcccgtcag tcccgtcagc cctgccagtc
    18421 ccgtcagcca catcagccac atcagccaca tcagaagagt gtgccctcct cgggcccctc
    18481 cagctccttc aacagctccg ggccgttgtt gcggacgttg ctcaccatcg tggagacggg
    18541 atacgcccgc atcagcccct ccggtggcgg cgcgagcagg gaacgcacgt cctcgacgtc
    18601 cgtgcgggag gggtcgagcc aggcgtccca acggtccggg gtgagcatga gcggcatacg
    18661 ggggtggatg tcggcgaggg agcgcgggcc ctcctcgggg gcgaccgcca gcggggaggt
    18721 ctccgcctcc gtggtgatga cggagcacgt cacccaccag gcccgcgggt ggtcgtcggg
    18781 cagggtcttg tcccgccaga actcgtacag cccggccatc gcgaagacgg aaccgtcggc
    18841 ggggagcacg aagtacggct gtttgcgggg ccgcttcttc ttgccctcga cctccaggtc
    18901 gcgctcgtcg gtgccggtca cccactcgta atagccgtcg gcggggatga cacagcgccg
    18961 ggaggtgaag gcccgccgga acgagggctt ctcgtggacg gtctcggcgc gggcgttgat
    19021 catccgggcg ccgccctcgg gcgtcttcga ccaggagggg atcaggcccc acttgaggcg
    19081 gcgcaactgc cgaaccggcc cggggtccgg tgcgtcctta acaggacggt ccaggaccac
    19141 gtagacctcc ttggtcggag ccacgttgaa atcggggtcc agagcctcct cgggctccca
    19201 cttctcgatt tcaaagattc ctgcgagatc ctcgggccca cgactcgctg cataccgtcc
    19261 gcacatacgt gcaacactgc cagatcccat agcccccaag ggagcccaag ccgaccatgg
    19321 acagcaccgc ggccacctcg ctggccaccc tctgggacga ggtcttcggg agccagcccg
    19381 accccgacac atgggtcgtc gtcgccacac tggccgccgc gctcgccgtg atcgtcccgc
    19441 acccgctgtg gcggctcgcg cgcaacgcca tcaccatcgc ccacgagggc ggccacggtc
    19501 tggtcgcgct gctcacgggc cgcagcctcg acggcatccg gctgcactcc gacaccagcg
    19561 gcctcaccgt cagccgcggc aagccgaccg gcctcggcat gatcctcacg gcgacggcgg
    19621 gctacacggc tcccccgctg ctcggcctgg gcggcgccgc gctgctggcc gcaggccaca
    19681 tcaccgccct gctgtggctg gccacgctgc tgctcgtggc cgtgctggtg atgatccgca
    19741 acgcatacgg cgcgctcacg gtcctcctga ccggcggcac gttcgtggtg gtgtcctggc
    19801 tgtgcggacc ccaggtgcag gcggcgttcg cgtacgccgt cgtctggttc ctgctgctcg
    19861 gcggggtccg cccggccttc gaactccagg cgaagcgcag ccgcggcgga gccggcgact
    19921 cggacgcgga ccagctgtcg aggctgacgc acgtaccggc gggcctgtgg ctgttcctct
    19981 tccacgcggt gtcgctgtgc tccctgatag gcggcggcag gtggctgctg gcgctgtgag
    20041 cgccgagtac ccaggggcgc ggggctgtgt cgatatgcgg ctccgccgcg tgggcgcgac
    20101 cggccacgac gcacccgcgg tcgacgtacc acccgcgttc ccggccgaac ccagcagagc
    20161 gaacccccac taaagtgagg gcatgcccgt taatcccgca gacaccgccc tctggcccgc
    20221 cccgcaccca ggcggagccg tcaacgcgac ggtccaggtg cccgggtcca agtcggtcac
    20281 caaccgcgcg ctcctcctcg ccgccctcgc cgccgagccc ggctggctcc gccgcccgct
    20341 gcgctcacgc gacactctcc tgatggccgg tgccctgcgg gcgatgggcg tcgggatcga
    20401 ggagggcgtg ggccccgacg gctccggcga ggcatggcgg gtcatcccct cggggctgcg
    20461 cggcccggcc acggtcgacg tgggcaacgc cggcacggtg atgcgtttcc tgccgccggt
    20521 cgccacactc gccgacggcc ccatccgctt cgacggcgac ccccgttcgt acgagcgccc
    20581 gctgcacggc gtgatcgacg ggctgcgcgc cctcggtgcc cggatcgacg acgacggccg
    20641 gggcgcgctg ccgctgaccg tgcagggcgg cggggcgctg gagggcggcc cggtggagat
    20701 cgacgcgtcc tcgtcctcgc agttcgtgtc ggcgctgctg ctgtcaggac cgcgtttcaa
    20761 ccagggcgtg gaggtacggc acaccggctc gaccctgccg tccatgccgc acatccggat
    20821 gaccgtcgac atgctgcggt cgatcggcgc ccaggtggac accccggagt cgggcggcga
    20881 gccgaacgtc tggcgggtca cgccgggcgc gctcctcggc cgggacctga cgatcgaacc
    20941 ggacctgtcg aacgcccagc cgttcctggc ggccgccctg gtcaccggcg gcacggtcgt
    21001 cgtccccgac tggcccgccc gcaccaccca gccgggcgac aggctgcgcg agatcttcac
    21061 cgagatgggc ggttcctgcg agctgacgga ccgggggc
//
