LOCUS       NZ_AP023440            21209 bp    DNA     linear   CON 26-MAY-2024
DEFINITION  Streptomyces aurantiacus strain JCM 4677 chromosome.
ACCESSION   NZ_AP023440
VERSION     NZ_AP023440.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces aurantiacus
  ORGANISM  Streptomyces aurantiacus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 9428393)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye
            Genome Coverage                   :: 62X
            Sequencing Technology :: Illumina HiSeq X Ten; PacBio Sequel II
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014701115.1-RS_2024_05_26
            Annotation Date                   :: 05/26/2024 05:58:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,211
            CDSs (total)                      :: 8,122
            Genes (coding)                    :: 7,928
            CDSs (with protein)               :: 7,928
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 194
            CDSs (without protein)            :: 194
            Pseudo Genes (ambiguous residues) :: 0 of 194
            Pseudo Genes (frameshifted)       :: 69 of 194
            Pseudo Genes (incomplete)         :: 161 of 194
            Pseudo Genes (internal stop)      :: 17 of 194
            Pseudo Genes (multiple problems)  :: 48 of 194
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:48:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1985228
            Orig. end                         :: 2006437
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP023440.1.
            Genome sequencing and analysis were conducted under the Global
            Catalogue of Microorganisms (GCM) 10K type strain sequencing
            project (http://gctype.wdcm.org). The genomic data are also
            available at http://gctype.wdcm.org/sequencing/GCM10017557
            Annotated by DFAST v.1.2.7 (https://dfast.nig.ac.jp).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21209
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="13"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21209
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21209
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11209](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11209)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    582..596
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.96"
                     /tool="antismash"
     gene            793..1662
                     /locus_tag="IGS71_RS08070"
                     /old_locus_tag="GCM10017557_16660"
     CDS             793..1662
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013706.4"
                     /locus_tag="IGS71_RS08070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_16660"
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="WP_190849822.1"
                     /transl_table=11
                     /translation="MLVSQTTGGVARVTGARYEVLEVGGASLSDLVKSGSMHLLAHART
                     VRTLERETVTVQVPIDAPGKVIIVGLNYRDHAAEMRTALPQVPRVHMTAASAVTGPGAD
                     IRLPRIAETAVDYEGEVAVVIGDPASDVSVEAAWDHVAGITAANDVSARDVQNGSNSLV
                     SGPNVGLAKGFDTFKPLGPALLTADSARDGRALALRTLVDGEIRQQSSTAQMHFSIAQL
                     VSRISQYTTLHRGDVVLTGTPGGVGASSGRFLQAGQVVEIELEGVGVLRNRVVAPSPTP
                     LSRNSTKS"
     gene            1695..2087
                     /locus_tag="IGS71_RS08075"
                     /old_locus_tag="GCM10017557_16670"
     CDS             1695..2087
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024092.4"
                     /locus_tag="IGS71_RS08075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_16670"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_055518142.1"
                     /transl_table=11
                     /translation="MSKAYVEYMYERLAEGDFGVVFEKLSPDAPWIEAENVPYSPGAPL
                     KGREAIQKTVFDSHEKDFAEFQINVSRIADAGDTVLVQGRYVGTTKTGAKLDAIFSHVW
                     DFDGDTIVRFQQYTDTWQWRRVLGLE"
     gene            2182..2976
                     /locus_tag="IGS71_RS08080"
                     /old_locus_tag="GCM10017557_16680"
     CDS             2182..2976
                     /NRPS_PKS="Domain: PKS_KR (10-130). E-value: 6.4e-10.
                     Score: 31.2. Matches aSDomain:
                     nrpspksdomains_IGS71_RS08080_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009073524.1"
                     /locus_tag="IGS71_RS08080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_16680"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_190849823.1"
                     /transl_table=11
                     /translation="MDLKLAGKRALVTGGSRGLGFAVAEELCGEGVRVALLARDAAAVE
                     SAAAGLRAAGHDAIGVVADTAQDRQVESAVAAATERFGGIDILVNGAAKAAGGPATGFL
                     ALHDDDLRSEMETKVLGYLRCARAVAPQMIESGWGRIINIGGLAMRRTGSVFGSVRNVA
                     VAAMSKNLADELGPKGVNVTVVHPWVTETEGVRDMIRDRSAAQGITEAEFAQDLAADVS
                     VGRLIRPSEVAHVVTFLASPLSVAINGEAVATGGGLSGPIFY"
     CDS_motif       2212..2298
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IGS71_RS08080_0001"
                     /evalue="1.60E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="IGS71_RS08080"
                     /protein_end="39"
                     /protein_start="10"
                     /score="17.6"
                     /tool="antismash"
                     /translation="LVTGGSRGLGFAVAEELCGEGVRVALLAR"
     aSDomain        2212..2571
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IGS71_RS08080_PKS_KR.1"
                     /evalue="6.40E-10"
                     /label="IGS71_RS08080_PKS_KR.1"
                     /locus_tag="IGS71_RS08080"
                     /protein_end="130"
                     /protein_start="10"
                     /score="31.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="LVTGGSRGLGFAVAEELCGEGVRVALLARDAAAVESAAAGLRAAG
                     HDAIGVVADTAQDRQVESAVAAATERFGGIDILVNGAAKAAGGPATGFLALHDDDLRSE
                     METKVLGYLRCARAVA"
     gene            3029..4204
                     /locus_tag="IGS71_RS08085"
                     /old_locus_tag="GCM10017557_16690"
     CDS             3029..4204
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030553.1"
                     /locus_tag="IGS71_RS08085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_16690"
                     /product="DUF3500 domain-containing protein"
                     /protein_id="WP_246596138.1"
                     /transl_table=11
                     /translation="MPTELGPAAESVAQAMSRAAMSWLADLDDEQRALAWWGPPGSEHE
                     AERRRWFYTPTDHGGLAFSGQFAWQQRRAMRLVASGLSPEGYDLVSTIIGTENVLDRLE
                     GFSSEFDTRRGRDPSRYYLRVFGDPEGQGPWSWRFGGHHVSLNFLIVAGKVRSATPRFF
                     GLDPAITTLPGGMTLEPLGAFQSTARSLVTSLPADARAAAVLLDRAPADIVMGNRSSFE
                     EAATMLNLAEIFRRRPGDDELMERMRKGGNSLDAETGYGPREHELLSVTSLPKGIAGSE
                     LDSDQRNLLDRLMRTYHDGLPVGLAPRWDIDELHFAWAGPTEAGVPNYYRVQGDGFLIE
                     WDNTARNGNHAHGVVRHLSNDFGEDVLAGHRRAWHTAEAGTNHLYQEDTQP"
     gene            4201..5004
                     /locus_tag="IGS71_RS08090"
                     /old_locus_tag="GCM10017557_16700"
     CDS             4201..5004
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015682.4"
                     /locus_tag="IGS71_RS08090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_16700"
                     /product="RraA family protein"
                     /protein_id="WP_055518149.1"
                     /transl_table=11
                     /translation="MTETTRQNFDWVDVHSMPKALPDGIVDRFLALDDMSATVADALDA
                     LGLHGCVGASTLPPTLPGERVVGRAVTLRNVPSRMDPHRAVTDGNWLMAEIHLVELAEP
                     GDVLVISGLPGVSNMGGIVAATARRSRLAGAVVDGAVRDVAQSRRRGFPIWSRDISPET
                     GKWRGSSVEINATIAVADVTVEPGDLVIADETGVCFVPVALSGEVIAHCEAIDKKEEQM
                     FADIAAGLPMADIINQLYGRPREGLLGQSPVSSSPTPAVNEKESL"
     gene            5001..5549
                     /locus_tag="IGS71_RS08095"
                     /old_locus_tag="GCM10017557_16710"
     CDS             5001..5549
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013098.4"
                     /locus_tag="IGS71_RS08095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_16710"
                     /product="VOC family protein"
                     /protein_id="WP_190849824.1"
                     /transl_table=11
                     /translation="MIVGIHHAAISTPDLERLKTFYCDLFGLEEVMRFGWEQGDELCDE
                     IVGLDGSAAKFVYLRGANAHLELFEYAHPTPKPRHADWRVCDHGFTHICFEVTDIHAEF
                     ERLTAAGMRFQNDAPIDALGMLHVAYGYDPDGNIVELVQFPEQDQDQEQEQGTKGDSAS
                     LTSTPLHIQASSGGRAGGQ"
     gene            complement(5543..6049)
                     /locus_tag="IGS71_RS08100"
                     /old_locus_tag="GCM10017557_16720"
     CDS             complement(5543..6049)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656959.1"
                     /locus_tag="IGS71_RS08100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_16720"
                     /product="hypothetical protein"
                     /protein_id="WP_190849825.1"
                     /transl_table=11
                     /translation="MNHSSYVSTVDADIRELRAADHLLLELAAELALPKGTFGCTHLLR
                     GDRPRVALSFTTNSEDAARRLTAKGYEVTPGAPDEEGRAVVYPGAAELTGTLTIAALLA
                     RSAIDRVVVLGAADEPPLSQLVVTRDHVRPQWQDGELILTLMPAVGGVLVPFEVPDPTP
                     CCADH"
     gene            complement(6046..7833)
                     /locus_tag="IGS71_RS08105"
                     /old_locus_tag="GCM10017557_16730"
     CDS             complement(6046..7833)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656960.1"
                     /locus_tag="IGS71_RS08105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_16730"
                     /product="PHP domain-containing protein"
                     /protein_id="WP_190849826.1"
                     /transl_table=11
                     /translation="MGHGHSHGHSHGHGHGHDHGHDHSHDHESAPLPAAFDTSVPDEAL
                     SPEQQSRRSMLRRAGLLGAGLATVGVFGGAATGTAAAQTSAAAQASAAAQASAGDRRGS
                     GQGKSKGNGFLWLAGDHHIHTQYSSDGKYRVVDQVRQGARHGMDWLVITDHGSAAHAKI
                     GVDKVNPDIRAARAAYEDTLVFQGLEWNIPGAEHGTVFVHPGKNEVSVLKQFETDYDGS
                     VKNASDSTPANEALAVAGLAFLGEQVQRRKVKDALMLANHPARRGVDSPHEIRAWRDAT
                     PASHQIAVGFEGAPGHQAAGLPAPLGMGRARGIYDNNPSANSFAGYPPESYRTWGGFDW
                     MTATVGGLWDSLLAEGKAWWISANSDSHQVYADTAARGGGDFNTDGRYQDPVYNGQIDV
                     TQGDYWPGQYSRTHVGAEDYSYAAVMDGIRAGRVWVDHGQLISGLDVRVSGGSRWATLG
                     GALHVKKGTNVTLTVDIALAQDANWAGFVPKLARVDVIQGDVTGPAVDKDTLTAPTTKV
                     VKSYEINKSTGTVRVTYSLGRVDRPLYLRVRGSDGNRSAVGSRGAAVDPAGPAIDVVGD
                     ADPWKDLWFYSNPLWVLPA"
     misc_feature    7892..7903
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     gene            8135..8716
                     /locus_tag="IGS71_RS08110"
                     /old_locus_tag="GCM10017557_16740"
     CDS             8135..8716
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996831.1"
                     /locus_tag="IGS71_RS08110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_16740"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_055518176.1"
                     /transl_table=11
                     /translation="MARAGLTTERVVVAAADLADEVGFAHVSLSALARRFGVKDASLYS
                     HVKNLDDLRTRIAFLAGAEMIDRIAEAVAGRAGQDALAAFADAYREYALEHPGRYAATQ
                     IRIDQSLAASSPAFARTAEVTYGMLRAYGLDEPDLTDAVRLLRSTFHGYCALEATGAFG
                     ASRDVRTSWTRAVAALHVTLEHWPREASTS"
     gene            complement(8725..9909)
                     /locus_tag="IGS71_RS08115"
                     /old_locus_tag="GCM10017557_16750"
     CDS             complement(8725..9909)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005307945.1"
                     /locus_tag="IGS71_RS08115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_16750"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_055518154.1"
                     /transl_table=11
                     /translation="MTTETRKHYCDTTLDELRNQGDPFADETVADMFERGEVRDFNTLM
                     RFFSTAGHKLPDGLPESAASFLEATAMPPKWVDWDVMERARLFFMDNAAHINTGLSFAA
                     MPATYAVPRVARLLASTHSMDYPSRRMANTGQFVTYLMQTNAFEEGSKFIPAAQKVRLL
                     HAAVRHHLTETGRWDIEKDGVPLCQEDMIGGQICFSILVLDAMHRLGIHMSEEGAEAYY
                     YAWRVVGSILGCDMEAAPDNLTEARAFADLYLARNLGPSEDGVRLNNQLMRMYEDVVPG
                     TLLDPIVPATIRFLVGPTIADWLQIPRSPWDTAAKAVPVVLGLLETVEDSSPLGEWALD
                     KAGSLLTTFELGSLTRGRVMQYAIPEELKSDYGVRSQAPRTHRWVPPAPTRAMP"
     gene            complement(10001..11209)
                     /locus_tag="IGS71_RS40995"
                     /old_locus_tag="GCM10017557_16760"
     CDS             complement(10001..11209)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980503.1"
                     /locus_tag="IGS71_RS40995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_16760"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_055518155.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 6.6e-26, bitscore:
                     89.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDDLTFRQRIDTYLHRLVDEEEAELVRLSGELAPLCAQLRSSLT
                     RGKRMRAAFLYWGWRAAGQPDCDGVIRAAAAMELVHAAACTHDDIIDDSRLRHGVPTAH
                     VAFAEAGARGWGTANPYPGSVRRRSLRRDSVWNESLRTDPLRTDSLRTDPLRADSLRTD
                     SLSPDHARQEKSAALAMMLGDLLMGYAAQVFATCGLPGAYVARTVPLWSTLLRETVAGE
                     FLEVLRTGSDAPEVTESLEVARYKTAKYTVERPLHMGATLGGAPRRVMEAFTAYGLPLG
                     EAFQLRDDLIGTFGDPAVTGKSNLDDLRDRKPTALLATTLSLLTPDARRLFEKTLDNPV
                     LDQSDAALVRRLMEECGARGRIEEMISERMAEARGALDSVPLPLEARAALAELATSAAD
                     RTL"
     misc_feature    complement(10922..10924)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11202..11627)
                     /locus_tag="IGS71_RS08130"
                     /old_locus_tag="GCM10017557_16770"
     CDS             complement(11202..11627)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IGS71_RS08130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10017557_16770"
                     /product="hypothetical protein"
                     /protein_id="WP_157871579.1"
                     /transl_table=11
                     /translation="MTEQPQDQTQDQTRNQTQDQAQQGQSQQGEGQAQSQSRQTPWNPF
                     GALEQVGLLVLGAVDLALDQVRQAADRSEGAVRRSDLRELVTDGVQDLKVRGELAARRV
                     TAADSENYLELMARRAGERKARTVDAARSETTVPSRA"
     misc_feature    complement(11753..11768)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.84"
                     /tool="antismash"
     gene            11888..13285
                     /locus_tag="IGS71_RS08135"
                     /old_locus_tag="GCM10017557_16780"
     CDS             11888..13285
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007502516.1"
                     /locus_tag="IGS71_RS08135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_16780"
                     /product="hypothetical protein"
                     /protein_id="WP_055518157.1"
                     /transl_table=11
                     /translation="MSQPQLRRGPLRRDPEPHAPHGPRPARLVRWLGGFGAVAAGYAVF
                     QSLVGILPDNIGGQSARYGIAVVSGLGTAVAAWLSAAVLRARSEANPPALAGQSRTSGT
                     GAMAGSGPLPGVFAAAYGALAEQICVVDDPVRGRLTGWSHSLGESGPGRPTSVGTAYGL
                     HIMLDLGMPEGRIGAGDLVDTLWRLRLADGGWSARSQGSQARPEVTALVLGALARAGAS
                     RERLAEEVAYCEAGFTRELDRAGRELTHVVTTVLRGLLRAAPGSEALPLLRDALVEGAV
                     TDPRREHRRCWGYRLTPLHGPPSALHTAQAVVALDRAARVLGSESANARAAREDGVRWL
                     LACPDATHDTCLDLSNLREEVRRPRTDDPSRHEVLNVRHFTASWIVRALLTPGARDIAR
                     EDGVEERWRELLNGAASAVWAGQTDGIWTWTWVRDDASELRHPMWMTYQGLSALRAHAV
                     WMYQPNG"
     gene            13302..14030
                     /locus_tag="IGS71_RS08140"
                     /old_locus_tag="GCM10017557_16790"
     CDS             13302..14030
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019063802.1"
                     /locus_tag="IGS71_RS08140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_16790"
                     /product="hypothetical protein"
                     /protein_id="WP_055518158.1"
                     /transl_table=11
                     /translation="MGGRQVLAARRLMAESLDGELPEHVRLLAARSVVAELGSPDRLLE
                     LTAELASGEGDPHGCARLSYRHVLGFDKLLLIDGGPHHMLRAHLWHPGRGAVGKEDIHN
                     HRSSLASSVVRGRLAMELYAPRGDGGIEADRYQESLADDGSADWLLERTGPARLHLTQV
                     AEYAAGSTYALPAHTLHRAWCDAAEPTVTLFLETGSGRRRHTDVFTAAGPHPGAVPKVP
                     MDVDDYVSELAALAELLRSS"
     gene            complement(14058..14501)
                     /locus_tag="IGS71_RS08145"
                     /old_locus_tag="GCM10017557_16800"
     CDS             complement(14058..14501)
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004981722.1"
                     /locus_tag="IGS71_RS08145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_16800"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_055518160.1"
                     /transl_table=11
                     /translation="MDDIPGNKRLAAAVVMREGLVLLVRRSETERFLPRVWGVPCGKLE
                     PGEHPEDGVLRELKEETGLLGEVVRKVGESSFVSEYRGHEVKNFQDNFMVRPLSQHITL
                     PEPDQAHRWLSPDELRTVDIDEYNLDIVRQALTGMLVSSRTSF"
     gene            complement(14618..15475)
                     /locus_tag="IGS71_RS08150"
                     /old_locus_tag="GCM10017557_16810"
     CDS             complement(14618..15475)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006383232.1"
                     /locus_tag="IGS71_RS08150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_16810"
                     /product="isocitrate lyase/phosphoenolpyruvate mutase
                     family protein"
                     /protein_id="WP_055518161.1"
                     /sec_met_domain="PEP_mutase (E-value: 6.1e-65, bitscore:
                     218.0, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPHEVSAFAALHRADAPLLLPNAWDHASAVALAAQGFPAIGTTS
                     LGVAAVAGLRDGSAATRDASLSLALALSDGPFLLSVDAEDGFSDDPAEVAQVARELAAV
                     GVVGINLEDGRADGILAPAELHAAKIAAVKAAVPGLFVNARTDTHWLGDGTGGPNGGPN
                     GGPNGGGDGGGDGGGHGGGLETVRRLDLYQQAGADGVFVPGLNAPGRIAALVKAVDVPL
                     NILYSPSGPTVATLADLGVRRVSLGSFLYRRALGAALEAAALIRAGLPVEGPAPTYGDV
                     QALV"
     misc_feature    15509..15523
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.02"
                     /tool="antismash"
     gene            complement(15601..17013)
                     /locus_tag="IGS71_RS08155"
                     /old_locus_tag="GCM10017557_16820"
     CDS             complement(15601..17013)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009294002.1"
                     /locus_tag="IGS71_RS08155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_16820"
                     /product="RICIN domain-containing protein"
                     /protein_id="WP_055518163.1"
                     /transl_table=11
                     /translation="MRRVYAVLLALCLALAGALATAGPAQAAPQTVTTGTQFTDTNGSP
                     VHAHGGGVVKVGSYYYWFGENRNTDNTFRYVDAYRSTDLKNWEFRNHVLTEASDPELAT
                     ANIERPKVMYNASTGTFVMWMHKENGVDYGEARAAVAVSDTVDGDYTWQGSFRPLGTHM
                     SRDITVFVDTDGAGYMVSAARENYDLQIYRLTADYTGIAGLVADPWHGGHREAPALFKR
                     GGVYFMLTSGATGWNPNQQQYATATSIAGPWTAMTNVGDSTTYGSQTAYVLPVQGSSGT
                     SYLYLGDRWGNSFGGTVNDSRYVWLPLAFPSSTTMSMSWSPEVTVDTAAGTVSGTSATY
                     NTLIARHSSKCADVTSQSLWARAQIKQYTCNGGTNQKYWFKSVGGGYYQLAVRGSSLCV
                     QENASSVTQEDCDGSATVQQWSLTITGSYVTITSRASGECLDVNGASTADSAALITYTC
                     NGATNQQWTRGG"
     gene            17371..18720
                     /gene="thrS"
                     /locus_tag="IGS71_RS08160"
                     /old_locus_tag="GCM10017557_16830"
     CDS             17371..18720
                     /EC_number="6.1.1.3"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thrS"
                     /gene_functions="other (smcogs) SMCOG1162: threonyl-tRNA
                     synthetase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005311225.1"
                     /locus_tag="IGS71_RS08160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_16830"
                     /product="threonine--tRNA ligase"
                     /protein_id="WP_079103962.1"
                     /transl_table=11
                     /translation="MNANANAHAHAHADARAQSDVNADADARADRDDHDGKGRDDRHDH
                     RRLGRELGLFDTDPLIGAGLPYWLPDGAVVRHTLEEYIRTEERRAGYRHVYSPVLGKRE
                     LYEISGHWAHYGDDMFPPMDLGAEQVVLRPSLCPHHAVIYRSRPHSYRELPLRMAELGG
                     MYRAELSGVLGGLTRVRAIQLNDAHIFCTLDQVAREAGDALEMIRRAYEALGITPARYR
                     LSLPGPGGKYVAAPELWQRATALLTEVLDRSGLPYEAAEGEAAFYGPKIDVQVADSAGR
                     ESTLSTVQIDFHQPERFGLHYIGADGGKHRPVMVHRSVIGSVERAVALLVEQHGGAFPA
                     WLAPTQLMVLPISEAELPNALALTRRCAERGLRAEIAGPERGTLGARVREARLVPYQAV
                     IGAREAADDLVALRLRDGRRLGPLPAEEAVDRIVALTDAHSTALWEDTAS"
     gene            18813..19736
                     /gene="mmuM"
                     /locus_tag="IGS71_RS08165"
                     /old_locus_tag="GCM10017557_16840"
     CDS             18813..19736
                     /EC_number="2.1.1.10"
                     /GO_function="GO:0047150 - betaine-homocysteine
                     S-methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mmuM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007502528.1"
                     /locus_tag="IGS71_RS08165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_16840"
                     /product="homocysteine S-methyltransferase"
                     /protein_id="WP_055518165.1"
                     /transl_table=11
                     /translation="MTSSTSPGSFPGTGTVVLDGGMSNQLRAAGHDLSDALWSARLLVE
                     RPEAITEAHLAYFEAGADVAITASYQATFEGFARRGISEKRAAELLALSVALAREAARQ
                     AGAKGARGPLWVAASVGPYGAMLADGSEYRGRYGLSVAELERFHRPRLEVLAEAGPDVL
                     ALETVPDADEARALLRAVRGLGVPAWLSYSITGDRTRAGQPLEEAFAVAADADEVIAVG
                     VNCCAPEDVDAAVATAARVTGKPVVVYPNSGETWDAGARAWRGRATFAPGQVTGWERAG
                     ARLIGGCCRVGPEAISRIAATLRALP"
     gene            <19741..>20196
                     /locus_tag="IGS71_RS41000"
                     /pseudo=""
     CDS             19741..>20196
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018957419.1"
                     /locus_tag="IGS71_RS41000"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKATAQAWDRLHPRLTRRAAWLDHDGPLPMIEGTVVRLVVEKLPS
                     GGVNKPVWLWWSGTGATELDVDRCWQSFLRRFDIEHTFRLFKQTLGWTRPRLRSSEAAD
                     RWTWLVIAAYAQLRLVRPLATDLRRPWEKPAEPNRLTPARVRRGFRNL"
     gene            complement(<20641..20983)
                     /locus_tag="IGS71_RS08170"
                     /pseudo=""
     CDS             complement(<20641..20983)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013678689.1"
                     /locus_tag="IGS71_RS08170"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="cation transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="MELRPGPGRDVLARRYGYSSRRPSPTT"
     gene            20982..21131
                     /locus_tag="IGS71_RS08175"
                     /old_locus_tag="GCM10017557_16860"
     CDS             20982..21131
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IGS71_RS08175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10017557_16860"
                     /product="hypothetical protein"
                     /protein_id="WP_157871581.1"
                     /transl_table=11
                     /translation="MKGADLLEEGGPQCRTSDGLIVQAVEDFRQQRDRFAQAVVQAHAD
                     FATL"
ORIGIN
        1 aactcggcca cctgcgcgtg gcgggaattc cctttgcgtt catggaagtg cttccgctgg
       61 tcataccgag gttccgggag gagaatcctc acgtcctcat cgacctccgt gaggccggga
      121 ctcaggagag cttcgactct ctgcgaaccg gggcgatgga catcgctttt gtacggcagg
      181 gcgagccggc cgccggcctt gaggtccttc ccctgctgac ggggcggttc gaactcatag
      241 ttccgcgcgg tcatcggctt gcgcgtgatc gtcccgtgga catcgtcgag ttggcgtcgg
      301 agccgcttgt catgacgtcg cgtcagatct caccttacta ttacgaccgg accctctccg
      361 ccatgaccgc cgtcgggata acgccgcata ccgtcgtgga ggcgacgtcc attcaagccc
      421 agttggggta cgtggccagc ggcatgggcg tttccttggt gccggcttcc gcgaagttga
      481 tgcactcgaa acacatcgaa tgggtcccgc tcaagcaggc gatcgtcatg acggaagtgg
      541 ccgcggtatg ggcttcgggg cctactccgc aggtcttgga caacttcctc aaaatcgtgc
      601 acgaagaatg cgtgggggat cgcgcccccg cgcggccggc ccgaacagcc tgatagctgc
      661 tgagtatcga cgtctgacct aacgagtatt ggaccgcacc ggccgtttcc ccgttacatg
      721 ggtgcagcga gtgttcggcg agacaggatc gtcggcggta ccacaggaac gaaggtcagg
      781 gaggtgctca ctgtgcttgt ttcgcagaca acaggcggag tggcgcgcgt aaccggagcc
      841 cgatacgagg tgctggaggt cggcggcgcg tccttgtccg atctcgtgaa atccgggtcg
      901 atgcacttgc tggcccatgc acggacggtc cgcactctgg aacgggagac ggtcaccgtg
      961 caagttccga tcgacgctcc cggaaaggtg atcatcgtcg ggttgaatta ccgggaccac
     1021 gccgcggaaa tgcggacagc actccctcag gtcccacggg tgcatatgac ggcggcctcc
     1081 gcggtcaccg gacccggcgc cgacattcga ctgccccgga tagcggagac ggcggtggac
     1141 tatgaaggag aggtggcggt ggtcatcgga gatcccgcgt ccgatgtgtc cgtggaggcc
     1201 gcctgggatc acgtggccgg gatcaccgcc gccaacgacg tgagcgccag agacgtccag
     1261 aacggcagca actccctggt gtccggcccc aacgtggggt tggcgaaggg attcgacacg
     1321 ttcaagccgc tcgggccggc gctcctgacc gcggacagtg cccgcgacgg ccgtgcgctg
     1381 gccctgcgca cgctggtcga cggagagata cgccagcagt ccagtaccgc gcagatgcac
     1441 ttctcgatcg cgcagctcgt gtcacggatc agccagtaca cgacgttgca ccgtggcgac
     1501 gtcgtcctga ccggcactcc aggcggcgta ggagcctcaa gcggtcgttt tctgcaggcc
     1561 ggacaggtcg tcgaaatcga gcttgagggc gtcggagttc ttcgcaaccg cgtcgtcgcg
     1621 ccttcaccga cgccgctttc ccggaactcc accaagagct gaactccacc aagagctagg
     1681 gacggtagaa cgttatgagt aaggcgtacg tcgagtacat gtacgagcgt ctggccgagg
     1741 gcgacttcgg ggtggttttc gagaagctct cgcccgacgc accgtggatc gaggcggaga
     1801 acgtgcccta ctcaccgggt gccccgctca agggccgcga ggcgatccag aagaccgtgt
     1861 tcgactcaca cgagaaggac ttcgcggagt tccagatcaa cgtcagccgc attgctgacg
     1921 cgggagacac cgtcctggtg caaggacgct acgtcggcac caccaagacc ggagccaagc
     1981 tcgatgcgat cttttcgcac gtgtgggact tcgacggcga cacgatcgtg cgctttcagc
     2041 agtacaccga cacatggcag tggcgccgcg tcctcggcct tgagtagcgg ccctgtcgaa
     2101 atatgcgcgg agtcgatatg cgcggagtcg acggaccggg cccatgcacg tcgccgaacg
     2161 gaacgacaag gagcaccaac agtggacttg aagctggccg gcaagagggc cctggtgacc
     2221 gggggcagcc ggggactggg gttcgcggtc gccgaggaac tgtgcggcga gggagtgcgt
     2281 gtcgcgcttc tcgccaggga cgccgccgcc gtcgagagcg cggcggccgg gcttcgcgcc
     2341 gcggggcacg acgccatcgg tgtcgtggcg gacaccgccc aggaccggca ggtcgagtcc
     2401 gcggtcgcgg cggcgacgga acgattcggg ggcatcgaca tcctcgtgaa cggagcggcc
     2461 aaggccgcgg gaggacctgc gacgggtttc ctggctctcc acgacgacga tctgcgctcg
     2521 gagatggaga cgaaggtgct gggctatctg cgctgcgcgc gggctgtcgc accccagatg
     2581 atcgaaagcg gctggggacg gatcatcaac atcggtgggc tcgcgatgcg gcgcacgggg
     2641 tccgtcttcg gctccgttcg caatgtcgcg gtcgcggcga tgtccaagaa cctggctgat
     2701 gaactcggcc ccaagggagt caacgtgacg gtcgttcacc cctgggtgac ggagaccgag
     2761 ggggttcgcg acatgatccg ggacaggtcg gcggcgcagg ggatcaccga ggccgagttc
     2821 gcccaggacc tcgccgccga cgtgagcgtc ggtcgcctca tacggccgtc cgaggtcgcg
     2881 cacgtggtga cgttcctggc ctctccgctg agtgtggcga tcaacggtga ggccgtcgcc
     2941 accggtggcg gcctgtccgg accgatcttc tactgaccac tgaccatggg aggagcacgt
     3001 gggagcgggc ctcggagaat ctcggcagat gccgactgag ctgggcccag cggccgaatc
     3061 agtcgcacag gccatgtccc gggcggccat gtcctggctg gccgacctcg acgacgagca
     3121 gcgcgccctg gcctggtggg gcccgcccgg aagtgaacac gaggcggagc gacgacggtg
     3181 gttctacaca cccacggacc acggcggtct ggccttcagc ggtcaattcg cctggcagca
     3241 gcggcgcgcg atgcgactcg tggcgtcggg gctgtctccc gagggttatg acctcgtctc
     3301 aacgatcatc ggcaccgaga acgttctcga tcggctggaa ggcttcagct cggaattcga
     3361 cacccgccgg gggcgtgacc cttcccggta ctacctccgg gtgttcggcg atccggaagg
     3421 tcaggggcct tggagttggc gcttcggcgg acaccatgtc tcgctgaact tcctgatcgt
     3481 cgcggggaag gtgcgctcgg ccacaccgcg cttcttcggg ttggaccccg cgatcacgac
     3541 actgccgggc ggcatgacac tcgaaccact gggcgcgttc cagtcgacgg caaggagcct
     3601 ggtcacctcg ctgccggccg acgcccgagc ggcggcggtg ctgctcgacc gggcgcctgc
     3661 cgacatcgtc atggggaatc ggtcgtcctt cgaggaggcc gcgaccatgc tgaacctggc
     3721 cgagatcttt cggcgacgac cgggtgatga cgagttgatg gaacgaatgc gcaagggcgg
     3781 caattccctt gacgcggaaa ccggatacgg gcctcgggaa cacgaactgc tgtcggtgac
     3841 gtccctaccg aaaggaatcg ccggctcgga actcgacagc gatcagagga accttctcga
     3901 tcgtctgatg cggacgtatc acgacggcct gcccgtcgga ctggccccac ggtgggacat
     3961 cgacgaactg cacttcgcct gggccggacc gaccgaagcc ggcgttccga actactaccg
     4021 ggtgcagggt gacggattcc tcatcgaatg ggacaacacc gcccggaacg gcaaccacgc
     4081 ccacggcgtc gtacggcatc tgtcgaacga cttcggtgaa gacgtcctcg ccggtcatcg
     4141 ccgggcgtgg catacggccg aggccggtac caaccacctc tatcaggagg acacacagcc
     4201 atgacggaaa ccacacgcca gaacttcgac tgggtcgacg tgcactcgat gccgaaagcg
     4261 ctgcccgacg gaatcgtcga ccgattcctc gcgctcgacg acatgtcggc cacggtggcc
     4321 gacgccttgg acgccctcgg cctgcacggg tgcgtcggtg cctcgaccct gcctcccacg
     4381 ctccccggtg agcgcgtcgt cggccgggcg gtgacgctcc ggaacgtgcc gtccaggatg
     4441 gacccgcacc gggctgtcac cgacggcaat tggttgatgg ccgagattca cctcgtcgaa
     4501 ctggcggaac ccggcgacgt gctggtcatc tcggggcttc ccggagtttc gaacatgggc
     4561 ggcatcgtcg cggcgacagc ccgacggagc cggctcgccg gcgccgtggt cgacggtgcg
     4621 gtccgggacg tggcgcagtc acgccggcgt ggtttcccca tctggagccg cgacatcagc
     4681 cccgagaccg ggaagtggcg cggcagttcg gtggagatca acgcgacgat cgccgtggcc
     4741 gacgtcaccg tggaaccagg cgatctggtg atcgccgacg agaccggtgt ctgtttcgtc
     4801 ccggtcgccc tgtcgggcga ggtgatcgcg cattgcgagg cgatcgacaa gaaggaggaa
     4861 cagatgttcg cggacatcgc tgccggtctc cccatggcag acatcatcaa ccagctgtac
     4921 gggcggccac gagaaggtct cctcggacaa tcccctgtgt catcgagccc gacccctgcg
     4981 gtcaacgaaa aggagtcact gtgatcgtcg gaattcatca cgcggcaata tcgactcccg
     5041 acctggaacg gctcaaaacc ttctactgtg acctcttcgg gcttgaggag gtgatgcgat
     5101 tcggctggga acagggcgac gagctgtgtg acgaaattgt cggactcgac ggatccgcgg
     5161 cgaagttcgt ctacctgcgc ggcgcgaatg cccaccttga actgttcgag tacgcccacc
     5221 ccacaccgaa gccgcgacac gcggactggc gagtgtgcga ccacggattc actcatatct
     5281 gtttcgaagt gacggacatc cacgccgagt tcgagcgact gaccgccgca ggcatgaggt
     5341 tccagaacga tgcgccgata gacgcactgg gcatgcttca cgtcgcgtac ggctacgacc
     5401 cggacggcaa catcgtcgag ctggtccagt tcccggaaca ggaccaggac caggaacagg
     5461 aacaggggac gaagggcgat tcggcttcac tgaccagtac tcccctgcac atccaggcaa
     5521 gttctggggg tcgagccggt ggtcagtgat ccgcgcagca cggcgtaggg tccgggacct
     5581 cgaacgggac caacacccct cccaccgccg gcatcaaggt caggatcagc tcgccgtcct
     5641 gccactgcgg tcgtacgtga tcccgagtca ccaccagctg ggacagcgga ggttcgtcgg
     5701 cggcgcccag caccacgacc cggtcgatcg cggagcgagc cagcagggcc gcgatcgtca
     5761 gcgtgccggt cagttcggcc gcgcccgggt agacgacggc ccggccctcc tcgtcgggtg
     5821 cgccgggcgt cacctcgtac cccttggccg tgaggcggcg tgcggcgtcc tcggagttcg
     5881 tcgtgaagga gagggcgacc cgtggccggt ccccgcggag caggtgcgtg cagccgaacg
     5941 tgcccttggg gagggctagt tcggctgcca gctccagcag caggtggtcg gccgcgcgca
     6001 gttcacgtat gtccgcgtcg accgtgctga cgtaggacga gtggttcacg cggggaggac
     6061 ccacagcggg ttcgagtaga accacaggtc cttccacggg tccgcgtcgc cgacgacgtc
     6121 gatggccggg cccgcggggt cgaccgccgc gccccgcgat ccgacggcgg accggttgcc
     6181 gtcggagccg cgcacgcgga ggtagagcgg gcggtcgacg cggccgaggg agtacgtgac
     6241 ccggaccgtg ccggtggact tgttgatctc gtacgacttg acgaccttgg tggtcggcgc
     6301 ggtgagcgtg tccttgtcga cggccgggcc ggtgacatcg ccctggatga cgtccacgcg
     6361 ggccaacttg ggtacgaagc ccgcccagtt ggcgtcctgg gccagtgcga tgtcgaccgt
     6421 cagcgtgacg ttcgtgccct tcttgacgtg cagcgcgccg cccagcgtgg cccagcggct
     6481 gccgccggag acccggacgt cgaggccgct gatgagctga ccgtggtcga cccacacgcg
     6541 tccggcgcgg atgccgtcca tcacggcggc gtacgagtag tcctcggcgc cgacgtgggt
     6601 cctgctgtac tggccgggcc agtagtcgcc ctgggtgacg tcgatctggc cgttgtagac
     6661 cgggtcctgg tagcggccgt cggtgttgaa gtcgccgccg ccgcgcgcgg cggtgtccgc
     6721 gtagacctgg tgcgagtcgg agttggcgct gatccaccag gccttgcctt cggcgagcag
     6781 gctgtcccag aggccaccga cggtggcggt catccagtcg aaaccgcccc aggtgcggta
     6841 gctctccggc ggatagccgg cgaaggagtt ggcgctcggg ttgttgtcat agatgccgcg
     6901 tgcgcggccc atgccgaggg gggcggggag gccggcggcc tggtggccgg gggcgccctc
     6961 gaagccgacg gcgatctggt ggctcgcggg ggtcgcgtcg cgccaggcac ggatctcgtg
     7021 cggcgagtcg acaccgcgac gggccgggtg gttggcgagc atcagcgcgt ccttgacctt
     7081 gcgccgctgg acctgctcgc cgaggaacgc caggcccgcg acggcgagtg cctcgttggc
     7141 gggcgtcgag tcggaggcgt tcttcacgct gccgtcgtag tcggtctcga actgcttgag
     7201 gacggagacc tcgttcttgc cgggatgcac gaagaccgtg ccgtgctcgg cgcccgggat
     7261 gttccattcg agaccctgga agacgagggt gtcctcgtac gccgcgcggg ccgccctgat
     7321 gtccgggttg accttgtcca cgccgatctt ggcgtgcgcg gcgctgccgt ggtccgtgat
     7381 gaccagccag tccatgccgt gcctggcgcc ctgcctgacc tggtcgacga cgcggtactt
     7441 gccgtcgctg ctgtactgcg tgtggatgtg gtggtcaccg gccagccaga ggaagccatt
     7501 gcccttgctc ttgccctgcc cgctccctct gcggtcaccg gccgacgcct gcgcggcagc
     7561 cgacgcctgc gcggcagccg acgtctgcgc ggcggccgtc cccgtcgccg caccgccgaa
     7621 gacgcccacc gtggccagcc ccgcgccgag cagacccgcg cggcgcagca tggaacggcg
     7681 cgactgctgt tcggggctca gggcctcgtc gggtacggac gtgtcgaagg ccgccgggag
     7741 cggggcgctc tcgtggtcat ggctgtggtc atgaccatgg tcgtgaccgt gcccgtgtcc
     7801 atggctgtgc ccgtgactgt gtccgtgccc catgtcggcc tcctgtgtac ggcgccgccg
     7861 gtgcggtcgc gcgctatgga gactcgatcc ggaacatgaa cgccgggcga cacgggagtg
     7921 atctccgggc gactccggca cggcgggtcg ccgccgttct tgccgtctcg ccaactgccc
     7981 ttatcagtca gcctagttga ctccagcccc ctggacgcgg ccggcggcat tggtcagcag
     8041 cttgctactc tctccaggtt cttgcctaga cgccctagga aagactcaga atggcccgga
     8101 aaataacgga aagtaacgga aagggttgcc gatcatggct cgtgccgggc tcaccaccga
     8161 gcgggtcgtc gtggccgccg ccgacctcgc ggacgaggtc ggcttcgcac acgtatcgct
     8221 gtccgcgctg gccagacggt tcggggtgaa ggacgcgagc ctgtactcgc acgtcaagaa
     8281 cctcgacgac ctgcggaccc ggatcgcgtt cctcgcgggc gccgagatga tcgaccggat
     8341 cgccgaggcg gtggccggac gtgccggcca ggacgccctg gccgccttcg ccgacgccta
     8401 ccgggagtac gccctggagc accccggccg gtacgcggcc acccagatcc gtatcgacca
     8461 gagcctcgcg gcctcgtccc ccgccttcgc cagaaccgcc gaggtcacct acgggatgct
     8521 gcgcgcgtac ggcctcgacg agcccgacct caccgacgcg gtacgcctgt tgcgcagcac
     8581 cttccacggc tactgcgccc tggaggccac cggcgcgttc ggcgcctccc gggacgtgcg
     8641 gacgtcgtgg acccgtgccg tggccgccct ccacgtgaca ctggaacact ggccccggga
     8701 agcaagcacc tcgtaacggg ccgcttacgg catggcccgg gtcggagccg gaggtaccca
     8761 gcggtgggtg cgcggcgcct gtgaacgtac gccgtagtcg ctcttgagtt cctccgggat
     8821 cgcgtactgc atgaccctcc cccgggtgag cgagcccagt tcgaaggtgg tgagcaggct
     8881 gcccgccttg tccagggccc attcgccgag cgggctgctg tcctccactg tctccagcag
     8941 gccgagtacg acgggtacgg ccttggccgc ggtgtcccag ggactgcgcg gaatctggag
     9001 ccagtcggcg atggtggggc cgacgaggaa gcggatggtc gcggggacga tggggtcgag
     9061 gagggtgccg gggaccacat cctcgtacat tcgcatcagt tggttgttca ggcggactcc
     9121 gtcctcggag gggccgaggt tgcgggcgag gtagaggtcg gcgaaggcgc gggcctcggt
     9181 gaggttgtcg ggggcggcct ccatgtcgca gccgaggatg gagcccacga cccgccacgc
     9241 gtagtagtag gcctccgctc cctcctcgct catgtggatg ccgagccggt gcatggcgtc
     9301 caggacgagg atggagaagc agatctggcc gccgatcatg tcttcctggc agagcgggac
     9361 accgtccttc tcgatgtccc agcgccctgt ttcggtgagg tgatggcgta cggccgcgtg
     9421 cagcagccgg accttctgcg ccgccgggat gaacttgctg ccctcctcga acgcgttggt
     9481 ctgcatgaga tacgtgacga actggccggt gttcgccatc cggcgtgacg ggtagtccat
     9541 cgagtgcgtc gaggccagca gtctggcgac gcgcggcacc gcgtaggtgg cgggcatcgc
     9601 cgcgaaggac agtccggtgt tgatgtgcgc ggcgttgtcc atgaagaaga gccgggcgcg
     9661 ctccatgacg tcccagtcca cccacttcgg cggcatggcc gtggcctcca ggaacgaggc
     9721 cgccgactcc ggcagcccgt ccgggagttt gtggcccgcg gtgctgaaga accgcatgag
     9781 ggtgttgaag tcgcgtacct cccctcgttc gaacatgtcg gccacggttt cgtcggcgaa
     9841 ggggtcgccc tggttgcgca gttcgtcgag cgtcgtgtcg cagtagtgct tccgggtctc
     9901 ggtcgtcacg gtgtgctcct ctgtggcgtg cgggagggga cggcggcgtg ggcggcgtgg
     9961 gccgcgtggg ccggtgtcgt tcgtaggtga gtcagcgggt tcacagcgtc cggtcggccg
    10021 ccgacgtggc caactcggcc agcgccgcgc gtgcttcgag cggcagcggc acggaatcca
    10081 gggcgccgcg agcctccgcc atccgctccg agatcatttc ctcgatgcgt ccgcgtgccc
    10141 cgcactcctc catcagccgc cgcaccagtg ccgcgtcgga ctggtccagt acggggttgt
    10201 cgagggtctt ctcgaacagc cggcgggcgt cgggggtcag cagggagagg gtcgtggcga
    10261 gcagcgcggt gggtttgcgg tcccgcaggt cgtccaggtt cgacttgccg gtcacggcgg
    10321 ggtcgccgaa ggtcccgatc aggtcgtcgc ggagctggaa ggcctcgccg agcggcagcc
    10381 cgtacgcggt gaaggcctcc atcacccgcc ggggggcgcc gccgagggtg gcgcccatgt
    10441 gcagtggccg ctccaccgtg tacttggcgg tcttgtagcg ggccacctcc agcgactccg
    10501 tgacctcggg tgcgtcgctg ccggtgcgca gcacctccag gaactcgccc gcgacggtct
    10561 cgcgcagcag cgtcgaccag aggggcaccg tccgggccac gtacgcgccc ggcagcccgc
    10621 aggtggcgaa gacctgggct gcgtaaccca tcagcaggtc accgagcatc atggcgagcg
    10681 cggcggactt ctcctgccgc gcgtgatccg gtgacaggga atccgttcgt agggaatccg
    10741 ctcgtagggg gtccgttcgt agggaatccg tccgcagggg atccgttcgc agggactcgt
    10801 tccacacgga gtcgcgccgc agggaacggc gtcgtacgga gccggggtac gggtttgcgg
    10861 tcccccatcc gcgcgcgccg gcctcggcga aggcgacgtg ggcggtgggc actccgtgcc
    10921 gtaaccggct gtcgtcgatg atgtcgtcgt gtgtgcaggc tgccgcgtgc accagctcca
    10981 tggctgccgc cgccctgatc accccgtcgc agtccggctg gccggcggcc cgccagcccc
    11041 agtacaggaa ggcggcgcgc atccgcttgc cccgggtcag cgaactgcgc aactgggcgc
    11101 acaacggcgc gagttcgccg gagagccgca ccagctcggc ctcctcctcg tcgaccagcc
    11161 ggtgcaggta cgtgtcgatg cgctgccgga acgtcagatc gtcatgcacg agacggcacc
    11221 gtcgtctccg accgcgcggc gtccacagtg cgtgctttcc gctctccggc cctgcgggcc
    11281 atcaattcca agtagttctc gctgtccgcg gcggtgaccc tgcgcgccgc gagttccccg
    11341 cgcaccttca ggtcctgcac cccgtccgtg accagttcac gcaggtcgga acggcgcacc
    11401 gcgccctcac tccggtctgc ggcctgccgc acctggtcga gcgcgagatc gacggctccc
    11461 agcacgagca ggccgacctg ttccagggcg ccgaacggat tccagggcgt ctgccgggac
    11521 tgcgattgcg cctgcccctc cccctgctgc gattgcccct gctgtgcctg atcctgcgtc
    11581 tggtttcgcg tctggtcttg cgtctgatcc tgcggttgtt cggtcatgtc agggcccctc
    11641 tgccgacaga tcgtcacgag gcgctcagtc aaccgacagg aaatgcggct ctgtccgcct
    11701 tttgcccctc cgtccctcgt cagagaagtg caattacctc tcacgggtga gctgttccct
    11761 ctcggagtgt gcgccggagc gcgtggcgga aacaccccct ccgctctccg ccccacacgc
    11821 cccgtgaacc acttagactg gaagcttcgc cagttcacgt gccgccctgg ggggagggag
    11881 cggaccaatg tcccaaccac agctccggcg cggcccgttg agacgcgacc ccgagccgca
    11941 cgcaccgcac ggaccccggc ccgcgcgcct cgtgcgctgg ctgggcggtt tcggcgccgt
    12001 cgccgccggt tacgcggtgt tccagtcact ggtgggcatc ctgccggaca acatcggcgg
    12061 ccagtccgcg cggtacggca tcgccgtggt gagcggactc ggtacggccg tcgcggcctg
    12121 gctctcggcg gcagtgctcc gggccagaag cgaggccaac ccgcccgcgc tggccgggca
    12181 gtcgaggacg tccggcacgg gtgccatggc gggctccggc cccctccccg gcgtcttcgc
    12241 cgccgcgtac ggcgccctcg ccgaacagat ctgcgtggtc gacgaccccg tacgcgggcg
    12301 gctcaccggc tggtcgcact ccctcggtga gagcggcccc ggccggccca cctccgtggg
    12361 caccgcgtac ggcctgcaca tcatgctcga cctggggatg cccgaagggc ggatcggcgc
    12421 gggcgacctg gtggacacgc tgtggcggct gcgcctggcg gacggcggct ggtcggcgcg
    12481 gtcgcagggc tcccaggccc gcccggaggt gaccgccctc gtcctgggcg cactggctcg
    12541 ggcaggggcg tcgcgggagc ggctggccga ggaagtggcg tactgcgagg caggcttcac
    12601 ccgcgaactc gaccgcgcgg gccgtgagtt gacgcatgtc gtgacgaccg tgctgcgcgg
    12661 tctgctgcgt gcggcgcccg gctcggaggc gctgcctctg ctgcgcgacg cgctggtgga
    12721 gggcgcggtc accgacccgc gccgcgagca ccgccgctgc tggggatacc ggctcacgcc
    12781 cctgcacggc ccgccgtccg cgctgcacac ggcgcaggcg gtggtcgccc tcgaccgcgc
    12841 ggcccgggtc ctgggcagcg agagcgccaa cgcgcgtgcg gcccgcgagg acggcgtgcg
    12901 ctggctgctg gcctgcccgg acgccacgca cgacacctgc ctggacctgt ccaacctccg
    12961 cgaggaggtg cgcaggccgc gcaccgacga cccgtcccgc cacgaggtcc tgaacgtacg
    13021 gcacttcacg gcgtcctgga tcgtccgcgc gctcctcacc cccggcgccc gcgacatcgc
    13081 gcgcgaggac ggcgtcgagg agaggtggcg cgagctgctg aacggcgcgg cgagcgccgt
    13141 gtgggccggg cagaccgacg gcatatggac ctggacctgg gtccgcgacg acgcaagcga
    13201 actgcgccac cccatgtgga tgacctatca aggcctttcg gcactgcggg ctcatgccgt
    13261 atggatgtac caaccgaatg gttgaaccgg gaggagcgtg catgggtggc cgacaggtcc
    13321 tggcggcgcg gcggttgatg gccgagtcgt tggacggcga actgcccgag cacgtacgac
    13381 tgttggcggc ccgctcggtc gttgccgaac tgggctctcc cgaccgcctg ttggagctga
    13441 cggccgaact cgcctccggt gagggagatc cgcacggctg cgcccggctc tcgtaccgcc
    13501 atgtcctcgg cttcgacaag ctcctgctca tcgacggcgg cccgcaccac atgctgcgcg
    13561 cccatctgtg gcatccgggg cgcggcgccg tcggcaagga ggacatccac aaccaccgct
    13621 cctcgctcgc ctcctccgtc gtacgggggc ggctggcgat ggagttgtac gcgccccgcg
    13681 gcgacggcgg tatcgaggcg gaccgctacc aggagtccct ggcggacgac ggttcggccg
    13741 actggctgct ggagcgcacg ggtccggcgc ggctgcatct cacgcaggtc gcggagtacg
    13801 cggcgggcag cacgtacgcc ctgcccgcgc acaccctgca ccgggcgtgg tgcgacgcgg
    13861 ccgagccgac ggtgacgctc ttcctggaga cggggagcgg gcggcggcgg cacaccgacg
    13921 tgttcacggc ggcggggccc cacccggggg ccgtaccgaa ggtgccgatg gacgtggacg
    13981 actacgtgag cgaactcgcc gcgcttgcgg agttgctcag aagctcgtaa gggaactcgt
    14041 gaagtagctg cagtcgctca gaagctcgta cgagagctta cgagcatgcc tgtgagggcc
    14101 tggcgcacga tgtccaggtt gtactcgtcg atgtcgacgg tgcgcagctc gtccggactc
    14161 agccagcggt gggcctggtc cggctcgggg agcgtgatgt gctgggagag gggcctgacc
    14221 atgaagttgt cctgaaagtt cttgacctcg tgcccgcggt actcgctcac gaaagacgat
    14281 tcgccgacct tgcgaacgac ctcgccgagc agcccggtct cctccttgag ctcccgcagc
    14341 acgccgtcct cggggtgctc gccgggctcc agctttccgc agggcacgcc ccacacccgg
    14401 ggcaggaacc gctcggtctc gctacggcgc accagcagga caaggccctc gcgcatcacg
    14461 acggccgcgg ccagccgctt gttaccggga atgtcgtcca tgcttcctgg ttccctcgcc
    14521 ggtcggagtc cacagagcct tatacccacg aaaacatcaa cgctaccagg aagcccgcac
    14581 gggcgtggcc gctctcggcc aaccgggacg gaaccggcta gaccagcgcc tggacgtcgc
    14641 cgtacgtcgg cgcgggcccc tcgacgggca gccccgccct gatcagggcc gccgcctcca
    14701 gggccgctcc cagggcgcgc cggtagagga aggacccgag gctgactcgg cggactccca
    14761 ggtcggcgag ggtggcgacg gtcggtcccg agggcgagta gaggatgttg aggggcacgt
    14821 cgacggcttt caccagggcg gcgatccgcc ccggcgcgtt cagaccgggt acgaacacgc
    14881 cgtcggcgcc ggcttgctga tagaggtcga gacggcggac cgtctcaagt ccgccaccgt
    14941 gccctccacc gtcccctcca ccgtcccctc ccccgttcgg gcctccgttc gggcctccgt
    15001 tcgggcctcc ggtgccgtct cccagccagt gggtgtccgt gcgggcgttg acgaagagcc
    15061 ccggtacggc ggccttcacc gcggcgatct tcgccgcgtg gagttcggcg ggggccagga
    15121 tgccgtcggc gcgcccgtcc tccaggttga tgccgacgac gccgacggcg gcgagttccc
    15181 gggccacctg ggcgacctcg gccgggtcgt cgctgaaccc gtcctcggcg tcgaccgaga
    15241 ggaggaacgg gccgtcgctc agcgccaggg ccagcgaaag cgacgcgtcc cgggtggccg
    15301 ccgaaccgtc gcgcaggccg gcgaccgcgg ccactcccag gctggtcgtg ccgatcgccg
    15361 ggaagccctg ggcggccagg gccaccgccg acgcgtggtc ccaggcgttg ggaagcagga
    15421 gcggggcgtc ggcccggtgg agtgcggcga aggcggatac ttcgtgggga gccatgcggc
    15481 aaggctaggc gcggaacgct tcggcgccgg ccgaagcgtt ccggggttcg ggaccggcct
    15541 caggacaggg ttcggggcag ggttcggggc aggagggcgc gggaaccttt ccggccgtgg
    15601 tcaacctccc ctggtccact gctggttggt cgctccgttg catgtgtacg tgatgagcgc
    15661 ggcggagtcg gcggtggacg cgccgttcac gtccaggcac tcgccactcg cccgggacgt
    15721 gatggtcaca taggagccgg tgatggtgag cgaccactgc tggacggtcg ccgagccgtc
    15781 gcagtcctcc tgcgtgacac tgctcgcgtt ctcctgcacg cacagggaac tgccccgcac
    15841 cgccagctgg tagtagccgc ctccgaccga cttgaaccag tacttctggt tggtgccacc
    15901 gttgcaggtg tactgcttga tctgggcgcg cgcccacagc gactggctgg tgacgtcggc
    15961 gcacttggag gagtggcggg cgatcagcgt gttgtacgtg gcgctcgtcc cggagacggt
    16021 cccggcggcg gtgtcgacgg tgacctccgg cgaccaggac atggacatcg tggtcgagct
    16081 cgggaaggcc agcggcagcc agacgtaacg ggagtcgttg accgtgccgc cgaaggagtt
    16141 gccccagcgg tcgcccaggt agaggtagga cgtgcccgaa ctcccttgca cgggaaggac
    16201 gtaggcggtc tgtgagccgt acgtcgtcga gtcgccgacg ttcgtcatcg ccgtccaggg
    16261 gcccgcgatc gacgtcgccg tggcgtactg ctgctggttg gggttccagc ccgtcgcgcc
    16321 cgacgtcagc atgaagtaga cgccgccccg cttgaagagc gccggggcct cgcggtggcc
    16381 gccgtgccag gggtccgcga ccagaccggc gatccccgtg tagtcggccg tcagccggta
    16441 gatctgcagg tcgtagttct cccgggcggc cgagaccatg taccccgcgc cgtccgtgtc
    16501 gacgaacacc gtgatgtcac gggacatgtg cgtgcccagc ggccggaagc tgccctgcca
    16561 ggtgtagtcg ccgtcgacgg tgtccgacac ggcgaccgcc gcacgggcct cgccgtagtc
    16621 gacgccgttc tccttgtgca tccacatcac gaacgtgccg gtggacgcgt tgtacatgac
    16681 cttgggccgc tcgatgttcg cggtcgccag ctcggggtcg ctcgcctcgg tcaggacgtg
    16741 gttgcggaac tcccagttct tcaggtcggt ggaacggtag gcgtccacgt accggaaggt
    16801 gttgtcggtg ttccggttct cgccgaacca gtagtagtat gagccgacct tgacgacccc
    16861 gccgccgtgg gcgtgcaccg ggctgccgtt cgtgtcggtg aactgcgtgc cggtggtgac
    16921 ggtctggggc gcggcctggg ccggccccgc ggtggcgagt gcgccggcca gggccagaca
    16981 gagggcgagg agtaccgcgt acacgcgtct catctcaggc acgctccttc gggggtcgtc
    17041 tctggggtgg gtggggccac aaaagaaaac agaaccgttc gacataccgc acaagatctg
    17101 tcatcccgaa cgccgaaaag gtaagggcat ggcacgagga ggtcaacggg ttgtggaagc
    17161 gcgcggaaaa ccgcgtgcgg gctccccggc cgccttgcta gcgtccccct catgaagcgc
    17221 gcccagaaga cgacgacgcc ggagagtgtc ccggcgcgct gactcatgag ttggtccgaa
    17281 gccccggggc gagtgccccg gggcttcggc gtacgcggtc actcgcccgg attccttccc
    17341 gtccgccccg tccgcgagga gatcgccgcc atgaatgcca acgccaacgc ccacgcccac
    17401 gcccatgccg atgcccgtgc ccaatccgac gtcaacgccg acgccgacgc ccgagccgac
    17461 agggacgacc acgacggcaa ggggcgtgac gaccggcacg atcaccgcag actcggtcgc
    17521 gagctcggtc tgttcgacac cgatccgctg atcggggcgg ggctgccgta ctggctgccc
    17581 gacggtgcgg tcgtgcggca caccctggag gagtacatcc gcaccgagga gcggcgcgcg
    17641 gggtaccggc acgtgtactc gcccgtgctg ggcaagcggg agctgtacga gatctccggc
    17701 cactgggcgc actacggcga cgacatgttc ccgccgatgg acctgggcgc ggagcaggtc
    17761 gtactgcggc cgagcctgtg tccgcaccat gcggtgatct accgttcccg cccccacagc
    17821 taccgcgaac tccccttgcg catggcggag ttgggcggca tgtaccgggc cgagctgtcc
    17881 ggcgtactgg gcgggctcac ccgtgtgcgg gcgatccagc tgaacgacgc gcacatcttc
    17941 tgcaccctgg accaggtggc gcgggaggcg ggggacgcgc tggagatgat ccgccgggcg
    18001 tacgaggcgc tcggcatcac ccccgctcgc taccggctct ccctgccggg cccgggcggc
    18061 aagtacgtcg ccgcgcccga gttgtggcaa cgggccaccg cgctcctgac cgaggtcctg
    18121 gaccgctcgg ggctgccgta cgaggcggcc gagggcgagg ccgcgttcta cgggccgaag
    18181 atcgacgtcc aggtggccga cagcgcgggg cgggagtcca ccctgtccac cgtgcagatc
    18241 gacttccacc agcccgagcg gttcggcctc cactacatcg gcgcggacgg cggcaagcac
    18301 cggccggtca tggtgcaccg cagtgtcatc ggcagcgtgg agcgggccgt cgccctgctc
    18361 gtggagcagc acggcggcgc ctttccggcc tggctcgccc cgacccagct gatggtcctg
    18421 cccatctcgg aggcggaact cccgaacgcc ctcgccctga cccgtcgttg cgccgagcgc
    18481 gggctccggg ccgagatcgc cggaccggag cgcggcaccc tgggcgcccg tgtccgggag
    18541 gcccggctgg tcccgtacca ggcggtgatc ggcgcgaggg aggccgccga cgacctggtc
    18601 gcactgcggc tgcgcgacgg gcggcggctg ggaccgctgc ctgccgagga ggccgtcgac
    18661 cggatcgtgg cgctgaccga cgcgcacagc accgcgctgt gggaggacac cgcctcgtag
    18721 gacggtgcag gacggtttac ggcagttggg cgggggccac gcgtgcggca ccttcggcgg
    18781 ggtgccgcac gcgcttcggc tagcgtcgtg acatgaccag cagcacctca cccggctcat
    18841 tccccggtac cggcacggtc gttctcgacg gcggtatgtc caaccagctc agggcggccg
    18901 ggcacgatct gagtgacgcg ttgtggtcgg cccggctgct cgtggagcgg ccggaggcga
    18961 tcaccgaggc ccacctcgcc tacttcgagg ccggcgccga cgtggcgatc accgccagtt
    19021 accaggcgac cttcgagggc ttcgcccggc gcggcatctc cgagaaacgt gccgccgaac
    19081 tcctcgcact gagcgtcgca ctcgcgcggg aggcggcccg gcaggccggc gcgaagggtg
    19141 cccgcgggcc gctgtgggtg gcggcgtcgg tgggcccgta cggggcgatg ctcgcggacg
    19201 gctccgagta ccgggggcgg tacgggctga gcgtggccga gctggagcgc ttccaccggc
    19261 cccgtctgga ggtgctggcc gaggcgggcc ccgacgtgct ggcccttgag accgtgccgg
    19321 acgccgacga ggcgcgggcg ctgctgaggg cggtgcgcgg gctcggcgta ccggcgtggc
    19381 tgtcgtacag catcaccggt gaccggacgc gggccgggca gccgctggag gaggccttcg
    19441 cggtggccgc cgacgccgac gaggtgatcg cggtcggcgt caactgctgc gcccccgagg
    19501 acgtggacgc cgcggtggcg accgccgcgc gggtgaccgg taagccggtc gtggtctacc
    19561 cgaacagcgg agagacctgg gacgccgggg cgcgtgcctg gaggggccgc gccacgttcg
    19621 cccccgggca ggtcaccggc tgggagcggg ccggggcgcg gctgatcggc gggtgctgcc
    19681 gggtggggcc ggaggcgatc tcgcggatcg cggccaccct gagggccctc ccctaatgat
    19741 gggaaggcaa ccgcgcaggc gtgggaccga ctgcacccgc ggctgacccg ccgggccgct
    19801 tggctcgacc acgacgggcc tctgcccatg atcgagggca ctgtcgtccg cctggtcgtg
    19861 gagaagctgc ccagcggcgg ggtcaacaag cccgtctggc tgtggtggtc gggcactggc
    19921 gcgaccgaac tggatgtcga ccgctgctgg cagtccttcc tccgccgctt cgacattgag
    19981 cacacatttc gcctgttcaa gcagaccctg gggtggacca gaccccggct ccgcagttcg
    20041 gaagcggccg accggtggac ctggttggtg attgctgcct atgcccagct ccggctcgtc
    20101 cgaccgctgg ccacggacct ccgcaggccc tgggagaagc cagccgagcc gaacaggctg
    20161 acacccgccc gcgtccgcag agggttcagg aacctgcacg cgaaaacagg gtctccagcc
    20221 agtgacactg tcgggaatct tggtttccga ggttgtcgat cacgacgaaa gtgccgggcg
    20281 agcgatccat ttccgcatcg ccaccgtgcg cacgctcagc accacggcga aggcgtccag
    20341 cgccgtcttc gggattcgca cctccgccgg ctcccgctcg atccctgcca ccgggcccgc
    20401 ttcacctcgt cgacaggccc gcgcctgccg tcgcggatca gcgtgacaga ccccgcaccc
    20461 cccgcacggt gtcactctgt gaagctgaca ggtgaccagg agcacgtcgc cgaaccggcg
    20521 cgaccgccac tcaccgcggc ccgcgcccgg gaaatgacgg acgggctgcg cgaggcgatg
    20581 gacgacgtcc ggctctccgt ggcggtcctc gccgcccgcg tctggctccc cctggggcac
    20641 aatgccggga atggggtgtt ccacttcccc ggtgccggtc agcgcccgca ccgcgtccac
    20701 gctcagattc gcggccaaca cgaagaacga gaccgcgatg atccgcaggg tggtcttctc
    20761 ccgggcctcg cgcacggcgt gctcgcgggc ggagaactgc caggcggccg cagcggcgga
    20821 ggtcacttcg atgatcgagt ctaggccgaa gccggccagc gcggtggagg aggcgcggtg
    20881 atggcggcga tcacctcggt cacgttgtag gtgatggtcg ccgcgacgag tagccgtagc
    20941 ggcgggcaag gacgtcacgc ccaggccccg gtcggagctc catgaagggc gcggacctgc
    21001 ttgaggaagg aggcccgcaa tgccgtacct ccgacggcct catcgttcag gccgttgagg
    21061 acttccggca gcagcgtgac cggttcgccc aggccgtcgt acaggcccac gccgacttcg
    21121 ccacgctgtg actagcgcct gatcagccgg aaaccaccgc ggatacctgc tggtcacaca
    21181 cgtcaaggca ggtcgcgggt atcccagcg
//
