LOCUS       NZ_AP023440            26744 bp    DNA     linear   CON 26-MAY-2024
DEFINITION  Streptomyces aurantiacus strain JCM 4677 chromosome.
ACCESSION   NZ_AP023440
VERSION     NZ_AP023440.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces aurantiacus
  ORGANISM  Streptomyces aurantiacus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 9428393)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye
            Genome Coverage                   :: 62X
            Sequencing Technology :: Illumina HiSeq X Ten; PacBio Sequel II
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014701115.1-RS_2024_05_26
            Annotation Date                   :: 05/26/2024 05:58:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,211
            CDSs (total)                      :: 8,122
            Genes (coding)                    :: 7,928
            CDSs (with protein)               :: 7,928
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 194
            CDSs (without protein)            :: 194
            Pseudo Genes (ambiguous residues) :: 0 of 194
            Pseudo Genes (frameshifted)       :: 69 of 194
            Pseudo Genes (incomplete)         :: 161 of 194
            Pseudo Genes (internal stop)      :: 17 of 194
            Pseudo Genes (multiple problems)  :: 48 of 194
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:48:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1364836
            Orig. end                         :: 1391580
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP023440.1.
            Genome sequencing and analysis were conducted under the Global
            Catalogue of Microorganisms (GCM) 10K type strain sequencing
            project (http://gctype.wdcm.org). The genomic data are also
            available at http://gctype.wdcm.org/sequencing/GCM10017557
            Annotated by DFAST v.1.2.7 (https://dfast.nig.ac.jp).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26744
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="8"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26744
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26744
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16744](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16744)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            1686..2483
                     /locus_tag="IGS71_RS05490"
                     /old_locus_tag="GCM10017557_11320"
     CDS             1686..2483
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069689.1"
                     /locus_tag="IGS71_RS05490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_11320"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_190849568.1"
                     /transl_table=11
                     /translation="MTQQVPSTEPELAGVRNFRDVGGLATTDGRRVAYGRLFRSGHLAH
                     ATASDAAFLASLGLHTVFDFRNAADQRLEGPDVELPGVRNMNLPLTDPADGAEFWKMVR
                     DGDLDELRALLSDGRAANRMIVSYRTIIKQRTAEHRQVLHALAEDSVPALMHCAAGKDR
                     AGLSVAVTLLALGVEREAIVADYLESNAAHRRYKVNRSSSAASAYTPEVMELLSPLFDA
                     RAEYLAAAFETIEETWGGVDAYLEQALGVTPETRERLRERFLD"
     gene            complement(2499..2624)
                     /locus_tag="IGS71_RS05495"
                     /old_locus_tag="GCM10017557_11330"
     CDS             complement(2499..2624)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386174.1"
                     /locus_tag="IGS71_RS05495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_11330"
                     /product="DUF6126 family protein"
                     /protein_id="WP_055509576.1"
                     /transl_table=11
                     /translation="MKDMEEKIPRGLWVRLIIYVAVGHVFAAFIYLLFTLGAKGQ"
     gene            complement(2621..3298)
                     /locus_tag="IGS71_RS05500"
                     /old_locus_tag="GCM10017557_11340"
     CDS             complement(2621..3298)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012999178.1"
                     /locus_tag="IGS71_RS05500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_11340"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_190849569.1"
                     /transl_table=11
                     /translation="MNSAKGTSPSEPAAAEEQLPAVAPQLRALRRRAALTLESAARAAG
                     LSPAHLSRLETGQRQPSLPMLLALARIYATTVSELLGETVAERDAVVRSADMEPTRAGG
                     WTYWQAGAAGRGMQSLRVHVPYGAQGDIVRVHPGEEWLYVLQGQLRLRLGDTAHVLAPG
                     DSAHFDSLTPHRIAAADRDGAELLFVHTLLQSPTAALCLGPATASAPPMTSTPSTTTPG
                     EGS"
     gene            complement(3442..4839)
                     /locus_tag="IGS71_RS05505"
                     /old_locus_tag="GCM10017557_11350"
     CDS             complement(3442..4839)
                     /NRPS_PKS="Domain: Aminotran_3 (45-367). E-value: 1.5e-90.
                     Score: 295.6. Matches aSDomain:
                     nrpspksdomains_IGS71_RS05505_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494124.1"
                     /locus_tag="IGS71_RS05505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_11350"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_190849570.1"
                     /sec_met_domain="Aminotran_3 (E-value: 7.1e-88, bitscore:
                     293.9, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSKSQEFDLGALLDARGAERYELHAKYLNHQLPRMLHTIGFDK
                     VYERAEGAYFWDADGNDYLDMLAGFGVMGLGRHHPVVRKALHDVLDAGLADLTRFDCQP
                     LPGLLAERLLAHSPHLDRVFFGNSGTEAVETALKFARYATGKPRVLYCAHAFHGLTTGS
                     LSVNGEDGFRDGFAPLLPDTAVPLGDLDALAAELKKGDVAALIVEPIQGKGVHESPPGY
                     LRAAQELLHRHKALLIADEVQTGLGRTGDFYAYQHEDGVEPDLVCVAKALSGGYVPVGA
                     TLGKDWIFKKVYSSMDRVLVHSASFGANAQAMAAGLAVLSVMENEQIVANARATGEQLK
                     TRLAALVDTYELLSDVRGRGLMIGIEFGRPRSLKLRSRWTMLQAARKGLFAQMVVVPLL
                     QRHRILTQVSGDHLEVIKLIPPLVVGERDVDRFVDAFTAVMDDAHSGGGLMWDFGKTLV
                     KQAVANR"
     aSDomain        complement(3739..4704)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IGS71_RS05505_Aminotran_3.1"
                     /evalue="1.50E-90"
                     /label="IGS71_RS05505_Aminotran_3.1"
                     /locus_tag="IGS71_RS05505"
                     /protein_end="367"
                     /protein_start="45"
                     /score="295.6"
                     /tool="antismash"
                     /translation="VYERAEGAYFWDADGNDYLDMLAGFGVMGLGRHHPVVRKALHDVL
                     DAGLADLTRFDCQPLPGLLAERLLAHSPHLDRVFFGNSGTEAVETALKFARYATGKPRV
                     LYCAHAFHGLTTGSLSVNGEDGFRDGFAPLLPDTAVPLGDLDALAAELKKGDVAALIVE
                     PIQGKGVHESPPGYLRAAQELLHRHKALLIADEVQTGLGRTGDFYAYQHEDGVEPDLVC
                     VAKALSGGYVPVGATLGKDWIFKKVYSSMDRVLVHSASFGANAQAMAAGLAVLSVMENE
                     QIVANARATGEQLKTRLAALVDTYELLSDVRGRGLMIGIEF"
     gene            complement(4836..7109)
                     /gene="dxs"
                     /locus_tag="IGS71_RS05510"
                     /old_locus_tag="GCM10017557_11360"
     CDS             complement(4836..7109)
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642848.1"
                     /locus_tag="IGS71_RS05510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_11360"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_246596028.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 1.4e-110,
                     bitscore: 367.7, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2e-05, bitscore:
                     23.3, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTILESIRGPRDLKALSEAEIGRLADEIREFLVQAVARTGGHLGP
                     NLGVVELSIALHRVFESPVDRILWDTGHQSYVHKMLTGRQDFSKLRGKGGLSGYPSREE
                     SEHDVIENSHASTALGWADGLAKARQVQGEKGHVVAVIGDGALTGGMAWEALNNIAAAK
                     DRPLIIVVNDNERSYSPTIGGLANHLATLRTTDSYEKVLAWGKDVLLRTPVVGGTLYES
                     LHGAKKGFKDAFAPQGMFEDLGLKYVGPIDGHDVGAVESALRRAKRFHGPVLIHCLTEK
                     GRGYEPALAHEEDHFHTVGVMDPLTCEPLAPSGGPSWTSVFGDEIVRIGEERADVVAIT
                     AAMLHPVGLAKFAERFPDRVWDVGIAEQHATVSAAGLATGGLHPVVAVYATFLNRAFDQ
                     LLMDVALHRCGVTFVLDRAGVTGADGASHNGMWDMSILQVVPGLRIAAPRDADQLRAQL
                     REAVAVDDAPTLIRFPKESVGPGIPAVDRVGGVDVLHRGERPDVLLVAVGVMAPVCLGA
                     AELLAARGIGCTVVDPRWVKPVDPALPGLAAGHRMVAVVEDNSRAAGVGAAVALALSDA
                     EVDVPVRRFGIPEQFLAHAKRGEVLADIGLTPVEIAGRISASLTVGEATGRAVTPDAHP
                     DARRDASSSAGPAAGRADGRAAAKRVRKAPTGGRRAAGSRKADPGGETRGAVAGAGPAD
                     TAEAPERRGAAARARKTPARRRGAAGPQAGGEGEAAGKQGATGKQSAAGEPAAKAHASE
                     EKPE"
     gene            complement(7140..8324)
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="IGS71_RS05515"
                     /old_locus_tag="GCM10017557_11370"
     CDS             complement(7140..8324)
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016570719.1"
                     /locus_tag="IGS71_RS05515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_11370"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_055509572.1"
                     /transl_table=11
                     /translation="MTAISLGLPEVPVRPIAERRVSRQIQVGPVAVGGGAPVSVQSMTT
                     TRTSDIGATLQQIAELTASGCQIVRVACPTQDDADALATIARKSQIPVIADIHFQPKYV
                     FAAIEAGCAAVRVNPGNIKQFDDKVKEIARAAKDHGTPIRIGVNAGSLDRRLLQKYGKA
                     TPEALVESALWEASLFEEHGFRDIKISVKHNDPVVMVNAYRQLAAQSDYPLHLGVTEAG
                     PAFQGTIKSAVAFGALLSAGIGDTIRVSLSAPPAEECKVGIQILESLGLRQRRLEIVSC
                     PSCGRAQVDVYKLADEVAAGLEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQI
                     FVRGEVIRTVPESKIVETLIDEAMKIAEQMEADGVASGEPQVTVPGQAAAATVS"
     gene            complement(8329..9351)
                     /gene="hpnH"
                     /locus_tag="IGS71_RS05520"
                     /old_locus_tag="GCM10017557_11380"
     CDS             complement(8329..9351)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742776.1"
                     /locus_tag="IGS71_RS05520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_11380"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_055509571.1"
                     /sec_met_domain="PF04055 (E-value: 3e-18, bitscore: 65.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 6.5e-05, bitscore: 22.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 1.9e-08, bitscore: 32.9,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQTIKVATYLAEQKLRKREKFPLIVELEPLYACNLACEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPKIDEIVRQLVARKKYVF
                     LCTNAMLMRKKMDKFKPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVAAIKEAKKRGF
                     RVTTNSTFFNTDTPQTIIEVLNFLNDDLKVDEMMISPAYAYEKAPDQEHFLGVEQTREL
                     FKKAFSGGNRRRWRLNHSPLFLDFLEGKVDFPCTAWAIPNYSLFGWQKPCYLMSDGYVT
                     TYRELIEDTDWDSYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESLRAARETVSGNRG
                     "
     gene            complement(9357..10001)
                     /locus_tag="IGS71_RS05525"
                     /old_locus_tag="GCM10017557_11390"
     CDS             complement(9357..10001)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330384.1"
                     /locus_tag="IGS71_RS05525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_11390"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_190849571.1"
                     /transl_table=11
                     /translation="MSATPGAAPLLIACALGIERLALRTGGDRGGAEGPVTVLRTGMGP
                     LAAERAVGRALAGPALSRAAVLATGFCAGLAPGMHPGDLVVAEETRGPHGTTPCVGTDL
                     LVKELTRALPGRTVHTGPLTGSDHVVRGPQRPALLATGAIAVDMESAATLHSAVRAGER
                     PVAAVRVVVDAPEHELVRIGTVRGGISAFRVLRAVLPVFFEWHRSLLLPRR"
     gene            complement(10001..12028)
                     /gene="shc"
                     /locus_tag="IGS71_RS05530"
                     /old_locus_tag="GCM10017557_11400"
     CDS             complement(10001..12028)
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994386.1"
                     /locus_tag="IGS71_RS05530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_11400"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_055509566.1"
                     /sec_met_domain="T2TS (E-value: 4.7e-150, bitscore: 499.6,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSTGALPPRAASASDIRTESTPAAAGTADVRDAAARAIQ
                     RATGFLLSTQDAEGWWKGDLETNVTMDAEDLLLRQFLGIDDEKTTHAAALFIRGEQRED
                     GTWASFYGGPGELSTTVEAYVALRLAGDAPDDPHMARAAAWIRERGGIAAARVFTRIWL
                     ALFGWWKWDDLPELPPELIYFPKWAPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFAL
                     DELHTDPRDPNPVKPFAPVASWDGVFQRLDRALHAYRKVAPRRLRRAAMNTAGRWIIER
                     QENDGCWGGIQPPAVYSVIALYLLGYDLEHPVMREGLASLDRFAVWREDGARMIEACQS
                     PVWDTCLATIALADAGVPADHPQLVRAADWMLGEEIVRPGDWAVKRPQLSPGGWAFEFH
                     NDNYPDIDDTAEVVLALRRVKHHDPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSP
                     FPNRLPFCDFGEVIDPPSADVTAHVVEMLAVEGLAHDPRTRRGIEWLLAEQEENGSWFG
                     RWGVNYVYGTGSVVPALVAAGLPGSHPAIRRAVSWLETVQNEDGGWGEDLRSYHDVAEW
                     SGRGESTASQTAWALLALLAAGEHDSKAVERGVAWLARTQLADGSWDEPYFTGTGFPWD
                     FSINYHLYRQVFPLTALGRYVNGEPFAGLQSSQSSFGRAS"
     misc_feature    12130..12145
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.62"
                     /tool="antismash"
     misc_feature    complement(12133..12148)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.27"
                     /tool="antismash"
     gene            complement(12141..13274)
                     /locus_tag="IGS71_RS05535"
                     /old_locus_tag="GCM10017557_11410"
     CDS             complement(12141..13274)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994385.1"
                     /locus_tag="IGS71_RS05535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_11410"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_079103225.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.8e-56, bitscore:
                     190.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLDQSAGTGARTPRIANRGETVPTVPPASKAADAVDVTALLERG
                     RTLASPVLRAAIDRLAPPMDTVAAYHFGWIDAEGNPADGDGGKAVRPALAVLSAQAAGA
                     APEVGVPGAVAVELVHNFSLLHDDLMDGDEQRRHRDTVWKVHGPAQAILVGDALFALAN
                     ELLLEIGTVEAGRATRRLTTATRALIDGQAQDISYEHRDRVSVEECLEMEGNKTGALLA
                     CASSIGAVLGGADDRTADTLEKYGYHLGLAFQAVDDLLGIWGDPVATGKQTWSDLRQRK
                     KSLPVVAALAAGGPASERLGELLAADAKRSDFENFSEEEFAARAALIEEAGGREWTAQE
                     ARRQHTVAVEALDTIHMPEQVRAQFVELADFVVVRKR"
     gene            complement(13271..14731)
                     /gene="hpnE"
                     /locus_tag="IGS71_RS05540"
                     /old_locus_tag="GCM10017557_11420"
     CDS             complement(13271..14731)
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983091.1"
                     /locus_tag="IGS71_RS05540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_11420"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_190849572.1"
                     /transl_table=11
                     /translation="MNDASQDEGLDADSASRPATAVVVGGGLAGITAALALADAGVRVT
                     LLEGRPRLGGLAFSFQRDALTVDNGQHVYLRCCTAYRWFLGRVDGADLAPLQARLDVPV
                     LDAGAKPGRRLGRIGRTALPVPLHLARSLATYPHLSLAERAKVGRAALALKRLDLADPA
                     LDTQSFGGWLAAHGQSERAIEALWDLVGVATLNAVAGDASLGLAAMVFKTGLLSAPGAA
                     DIGWARVPLGELHDRLARKALDSAGVRTEVRTRVTSISRPGPIHQDGSISPHENGRWRV
                     QVPGETLDADAVVLAVPQREAHDLLPEGALDAPERLLDIGTAPILNIHVVYDRKVLSRP
                     FFAALGSPVQWVFDRTEASGLKEGQYLALSQSVAQDEIDEPVSALRERYLPELERLLPR
                     ARDAAVQDFFVTRERTATFAPAPGVGRLRPGARTEAPGLYLAGAWTATGWPATMESAVR
                     SGVSAADAALDALGRPRDHLVELFEEAA"
     misc_feature    14851..14866
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.39"
                     /tool="antismash"
     gene            complement(14895..15845)
                     /gene="hpnD"
                     /locus_tag="IGS71_RS05545"
                     /old_locus_tag="GCM10017557_11430"
     CDS             complement(14895..15845)
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006139892.1"
                     /locus_tag="IGS71_RS05545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_11430"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_055509559.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.6e-55, bitscore:
                     187.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 5.7e-69,
                     bitscore: 231.5, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTVESEPHMSAPVLAAYGYCEAITGQQARNFAYGIRLLPTPKR
                     RAMSALYAFSRRVDDIGDGALAPEVKAARLEETRVLLARIRDRAVDEDDTDPVAVALRH
                     TADHFPVPLDGLDELIDGVLMDVRGETYETWDDLKVYCRCVAGAIGRLSLGVFGTESGA
                     RGAERAPEYADTLGLALQLTNILRDVREDAEGGRTYLPADDLAKFGCSAGFDGPRPPEG
                     SDFAGLVHFEVRRARALFAEGYRLLPMLDRRSGACVAAMAGIYRRLLDRIERDPEAVLR
                     GRVSLPGREKAYVAVRGLSGLDARHVSRRTIRRRA"
     gene            complement(15842..16744)
                     /gene="hpnC"
                     /locus_tag="IGS71_RS05550"
                     /old_locus_tag="GCM10017557_11440"
     CDS             complement(15842..16744)
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010042802.1"
                     /locus_tag="IGS71_RS05550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_11440"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_190849573.1"
                     /sec_met_domain="phytoene_synt (E-value: 8.1e-36, bitscore:
                     122.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 4.7e-38,
                     bitscore: 130.0, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPAGTARAGDPERSTLDKAADENFPVAPFFLPRAWRADLMAVYG
                     FARLVDDIGDGDLAPGGQDARLLGVSPDEAEDRLVLLDAFEADLHRVFDSTPGHPLLRR
                     LQPTVRRTGLIPEPFLGLIAANRQDQIVKRYETYDDLLAYCELSANPVGRLVLSVTGTS
                     TPERVRRSDAVCTALQIVEHLQDVAEDLGRDRIYLPAQDMKRFHVQEADLATATAGASA
                     RALVAYETERAGNLLNEGTPLVGSVHGRLKLLLAGFVAGGRAAIRAIAAAQYDVLPGPP
                     KPGKIQLLREVGVTLRGKG"
     gene            complement(17129..17908)
                     /locus_tag="IGS71_RS05555"
                     /old_locus_tag="GCM10017557_11450"
     CDS             complement(17129..17908)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330378.1"
                     /locus_tag="IGS71_RS05555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_11450"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_190849574.1"
                     /transl_table=11
                     /translation="MAEQNTGSTIPTVIADELHIVYRVNGARTGKGSATSALSRIVRRG
                     EERGVRKVHAVRGVSFKSYRGEAIGLIGSNGSGKSTLLRAIAGLLPAEKGHVYTDGQPS
                     LLGVNAALMNDLTGERNVILGGLAMGMTREQIRERYQDIVEFSGINEKGDFITLPMRTY
                     SSGMAARLRFSIAAAKDHDVLMIDEALATGDRSFQKRSEARIRELRKSAGTVFLVSHNN
                     KSIRDTCDRVLWLERGELRLDGPTGEVLKEYEKFTGK"
     gene            complement(17901..18830)
                     /locus_tag="IGS71_RS05560"
                     /old_locus_tag="GCM10017557_11460"
     CDS             complement(17901..18830)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994380.1"
                     /locus_tag="IGS71_RS05560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_11460"
                     /product="ABC transporter permease"
                     /protein_id="WP_190849575.1"
                     /transl_table=11
                     /translation="MSETTHDGGVAVSAPPSPDDGLTAADLAAKYGLAVSGARPGLVEY
                     VHQLWGRRHFILAFSQAKLTAQYSQAKLGQLWQVATPLLNAAVYFLIFGLILKADRGMS
                     REVYIPFLVTGVFTFTFTQSSVMAGVRAISGNLGLVRALHFPRAALPISFSLQQLQQLL
                     FSMIVLFVVAVGFGSYPQLSWLLIVPVLVLQFLFNTGLAMIMARMGSKTPDLAQLMPFV
                     MRTWMYASGVMFSIPVMLEEHPAWIADILQWNPAAIYMDLMRFALVDGYGSENLPPHVW
                     AVAGGWAVLVAVGGFVYFWKAEERYGRG"
     gene            complement(18928..19821)
                     /locus_tag="IGS71_RS05565"
                     /old_locus_tag="GCM10017557_11470"
     CDS             complement(18928..19821)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983096.1"
                     /locus_tag="IGS71_RS05565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_11470"
                     /product="glycosyltransferase"
                     /protein_id="WP_190849576.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.6e-14,
                     bitscore: 51.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAMRVGAVIITMGNRPDELRALLDSVAKQDGDPVEVVVVGNGS
                     PVPDVAGSAPGLRTVELPENLGIPGGRNVGIEAFGPGGTDVDVLLFLDDDGLLAHHDTA
                     ELCRQAFAADPELGIISFRIADPETGITQRRHVPRLRASDPMRNSRVTTFLGGANAVRT
                     KVLAEVGGLPDEFFYAHEETDLAWRALDAGWMIDYRSDMVLNHPTTAPSRHAVYHRMVA
                     RNRVWLARRNLPAPLVPVYLGVWMLLTLARRPSRPALQAWFGGFKEGWTSPCGPRRPMK
                     WRTVWRLTRLGRPPVI"
     gene            complement(19818..20597)
                     /locus_tag="IGS71_RS05570"
                     /old_locus_tag="GCM10017557_11480"
     CDS             complement(19818..20597)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049651.1"
                     /locus_tag="IGS71_RS05570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_11480"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_190849577.1"
                     /transl_table=11
                     /translation="MQKPSVAELRPVVHPPGVKDRRSGEHWGGRLYMREISLRIDRHLV
                     NTKVTPNQLTYVMTVFGVLAAPALLVPGIPGAVLGVLMVQLYLLFDCVDGELARWRKQY
                     SMTGVYVDRVAAYLCDAAVLVGFGLRAADLWGTGRIDWLWAFLGTLAALGAVLIKSETD
                     LVGVARHQTGKAPVQESASEPRSSGMALARRAAGALKFHRLVLGIEASLLILVLAVLDT
                     VRDDLFFSRLGVAVLAGIAVLQTVLHLVSILASSRLK"
     gene            complement(20575..21636)
                     /locus_tag="IGS71_RS05575"
                     /old_locus_tag="GCM10017557_11490"
     CDS             complement(20575..21636)
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494151.1"
                     /locus_tag="IGS71_RS05575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_11490"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_055509548.1"
                     /sec_met_domain="Fe-ADH (E-value: 4.3e-22, bitscore: 77.3,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRPGALDDLAAVLADQRISHSGKLAVAISA
                     GSGAKLRERLAPAMPGADWFEVGGGTLDEAIKLADAMKKGRYDAVVGLGGGKIIDCAKY
                     AAARIGLPLVAVATNLSHDGLCSPVATLDNDAGRGSYGVPNPIAVVIDLDVIREAPVRF
                     VRSGIGDALSNISAVADWELANREKGEKIDGLAAAMARQAGEAVLRHPGGVGDDGFLQV
                     LAEGLVLTGISMSVAGDSRPASGACHEINHGFDLLFPKRAASHGEQCGLGAAFAMHLRG
                     AREESAYMAEVLRRHGLPVLPEEIGFTPDEFVQVVEFAPSTRPGRYTILEHLALSTDQI
                     RDAYADYAKAIGS"
     gene            complement(21624..22385)
                     /locus_tag="IGS71_RS05580"
                     /old_locus_tag="GCM10017557_11500"
     CDS             complement(21624..22385)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983099.1"
                     /locus_tag="IGS71_RS05580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_11500"
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="WP_190849578.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 7.4e-09, bitscore:
                     35.0, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDVLPKALVPVGPEGAADDEDSITVLDL
                     TLGNFAEIGLTEVAVIVGYRKEAVYERREALEQKYGVKITLIDNDKAEEWNNAYSLWCG
                     RDAIKHSVILANGDTVHPVSVEKTLLAARGDGKKIILALDTVKSLADEEMKVVVGPEGD
                     MTKITKLMDPAEATGEYIGVTLIEGDAADELADALKTVFEADPQQFYEHGYQELVNRGF
                     RIDVAPIGDVKWVEIDNHDDLAKGREIACQY"
     gene            complement(22382..24193)
                     /locus_tag="IGS71_RS05585"
                     /old_locus_tag="GCM10017557_11510"
     CDS             complement(22382..24193)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996269.1"
                     /locus_tag="IGS71_RS05585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_11510"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_190855092.1"
                     /transl_table=11
                     /translation="MSTAILTGQPVPGSSLEGDLRSLGYDVRAAADAADAETLLAAVPA
                     DQRVAVVDARFVGHVHALRLGLTDPRFDAAAIPGAVTAKPAARAALGRALRTASTDASN
                     GSVVVGIVTDRVADALDTDLHRPELGELVAEVPRDPQARNEARQAVASVDEEAIRLRTA
                     VKSRDGFFTTYCISPYSRYIARWCARRGLTPNQVTTASLLTALIAAGCAATGTRAGFVA
                     AGLLLLCSFVLDCTDGQLARYSLQYSTLGAWLDATFDRAKEYAYYAGLALGAARGGDDV
                     WALALGAMVLQTCRHVVDFSFNEANVNSTPGPGATANSSPTAAFSDRLDGVGWTVWLRR
                     MIVLPIGERWAMIAVLTALTTPRITFYVLLVGCAFAACYTTAGRVLRSLTRRAQRTDQA
                     ARALADLADSGPLAESLARVIPSPLPVLARLLALAGAVVVVLAAWIDGPGWSTVVCAVA
                     YVLVSGDVVARPLKGPLDWLLPPLFRATEYGTVLILAAKADVNGALPAAFGLVAAVAYH
                     HYDTVYRIRGGAGAPPHWLVRAIGGHEGRTLLVAVLAALLTATDFKVALTVLAVAVALL
                     VLFESIRYWVTAHRRGAPAVHDEGEPA"
     misc_feature    complement(24297..24311)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.45"
                     /tool="antismash"
     misc_feature    24373..24387
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            24489..25466
                     /gene="galE"
                     /locus_tag="IGS71_RS05590"
                     /old_locus_tag="GCM10017557_11520"
     CDS             24489..25466
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (65-206). E-value:
                     2.8e-11. Score: 34.9. Matches aSDomain:
                     nrpspksdomains_IGS71_RS05590_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019058843.1"
                     /locus_tag="IGS71_RS05590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_11520"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_190849579.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 3.6e-18, bitscore:
                     64.5, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 2.2e-09,
                     bitscore: 35.7, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLITGGAGYIGAHVARAMAEAGERVLALDDLSAGVPSRLPEGI
                     PLVQGSSLDGELLKRVLAEHAVTGVVHLAARKQVGESVAQPARYYQENVGGLATLLDAV
                     AGAGVERFLFSSSAAVYGNPDAELITEDTPCAPMSPYGETKLAGEWLVRAAGRAHGIRT
                     VCLRYFNVAGAAAPELADTGVFNVVPMVFDRLTRGEAPRIFGDDYPTPDGTCVRDYIHV
                     ADLAEAHLAAARRLSSADAADGAGDLTVNIGRGEGVSVRELVTLIGEVTGDTRPVRVEP
                     RRPGDAPRAVASAAVAAGELGWTARRGVREMVESAWRGWQLHHA"
     CDS_motif       24492..24578
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IGS71_RS05590_0001"
                     /evalue="4.50E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="IGS71_RS05590"
                     /protein_end="30"
                     /protein_start="1"
                     /score="25.7"
                     /tool="antismash"
                     /translation="TWLITGGAGYIGAHVARAMAEAGERVLAL"
     aSDomain        24684..25106
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IGS71_RS05590_NAD_binding_4.1"
                     /evalue="2.80E-11"
                     /label="IGS71_RS05590_NAD_binding_4.1"
                     /locus_tag="IGS71_RS05590"
                     /protein_end="206"
                     /protein_start="65"
                     /score="34.9"
                     /tool="antismash"
                     /translation="AVTGVVHLAARKQVGESVAQPARYYQENVGGLATLLDAVAGAGVE
                     RFLFSSSAAVYGNPDAELITEDTPCAPMSPYGETKLAGEWLVRAAGRAHGIRTVCLRYF
                     NVAGAAAPELADTGVFNVVPMVFDRLTRGEAPRIFGD"
     gene            25799..26392
                     /gene="idi"
                     /locus_tag="IGS71_RS05595"
                     /old_locus_tag="GCM10017557_11530"
     CDS             25799..26392
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="idi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129457.1"
                     /locus_tag="IGS71_RS05595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_11530"
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_055509540.1"
                     /transl_table=11
                     /translation="MPITPATATHSSSNGAAEAILLELVDEDGVTIGTAEKLTAHQPPG
                     QLHRAFSVFLFDERGRLLLQQRALGKYHSPGVWSNTCCGHPYPGEAPFAAAARRTYEEL
                     GVSPSLLAEAGTVRYNHPDPASGLVEQEFNHLFVGMVQSALRPDPEEVGSTAFVSAAEL
                     AERHAADPFSAWFMTVLDAARPAIRELTGAPAGW"
ORIGIN
        1 ccgcccgagc aggactcgaa ggcgacggtc gggtgcgccg cccgcaaccg gtccaacagg
       61 ccgtacagag cgtgcacatg gtccacccac agccgttgcg ggtaggcctc gccgggccat
      121 cccgcgtcgg tgaagctgcg gttgaagtcc cacttcacgt agtcgatcgg cgcgccggcg
      181 agcagcgcgt cgagctgttc ccacaggtac tcctggacat cctcgcgggc gaggttcagt
      241 acgagctgat tgcgtagctc cgtcctcttt cgtcccggct ggaactgcac ccagtccggg
      301 tgggcgcggt acagctcgct gtccgggttg accatctcgg gctcgaccca gatcccgaac
      361 cgcatcccga gcccgtgcac gtagtcgccc agcggttcga gaccgcccgg gaagcggtcc
      421 gggttgggcg tccagtcgcc gagcccggcc cggtcgctgg tgcgcgcccc gaaccagccg
      481 tcgtcgacca cgaacagctc cacccccgtc tcggcggccc ggcgcgcgag cgcccgctgc
      541 tgctcctccg agatgtcgaa ctcggtggcc tcccaggagt tgtagagcac gggccggtcc
      601 cggtccgcgt ccgggatgac atacgcgcgc tggtaggcat gccaggcgcg gctcgccccg
      661 ccgaagccgc cgtcgctcca cagccccgcg aagacgggag tgacgaagct ctcccccggc
      721 tccagccgca gcaggcccga gtcgtcgtac ccggccccgc cggtgatctg cacgcgcgcg
      781 tcgggcagtt gggccaccgc gatccgccag gtgcccgacc aggcgagggc gcacccgtag
      841 acctcgccca gctcctcggt cgccgtgccg tcggcgtcca gggcgaccca cggcaggtgc
      901 tggtgcccgg tgtgcccgcg ccggctgccg atgatcttct cgccgtaggt gagctcggag
      961 cgcaccagac gggactcggc cgcccaccgt ccgtgcagct gggacagccg ccatccgtcg
     1021 cgccgcggca gcgtccaggt cgcggagtcg gcgcgcagca cctccaggac gggcccttcg
     1081 ttggcgaggg tcacccatcg ctcgacgacg tcggcgccgg cccgcatccg gtagtgcagc
     1141 gtgatgccga gcccggagtc ggagaaccgc agccgcagct cgccgccccc ggccccacct
     1201 tcggggtcgg ctccgtcggt ctcgtacccc tcgaagcgcc attcggtgcc gcgccgctcc
     1261 ggggtacgca ccgacagtgc gggccgtacg aagcgggggc cgccctcgac cgggtattcc
     1321 tcgtggccgt cgagggtggc ctcgaacgcc cagtactccg gtccggggcc cgcggcgagc
     1381 gcctcggcgt cggcgagctc gatcctcgga ccccagtgca gatgaaccag ctcgtcctcg
     1441 tcaccgagcc gcaggccgta actgctcgtg ggccccgaaa ggagccacgt ccggccgtct
     1501 gcgccgatct ctaccatcaa accctcacat attcgaacag gcacaaccaa gtcccaacat
     1561 catcagggcc cacgtgccgt ccgggcaacg cctgtggaca actcattggc ccacgaaccg
     1621 atgtcgtatc gtcgggaagg cacctcgccg acgagtcgcg tcggcggtgg atgggaggag
     1681 cccccgtgac gcagcaggtc ccgtcgaccg agcccgagct ggccggcgtg cgcaacttcc
     1741 gcgatgtcgg cggcctggcg acgacggacg gccggcgggt ggcgtatgga aggctgttcc
     1801 gcagcggcca cctcgcgcac gcgacggcgt cggacgccgc gttcctcgcc tcactggggc
     1861 tgcacacggt cttcgacttc cgcaacgcgg cggaccagcg gctggagggc cccgacgtcg
     1921 agctgcccgg ggtgcggaat atgaacctgc cgctgacgga ccccgccgac ggcgccgagt
     1981 tctggaagat ggtccgcgac ggggatctgg acgagctgcg tgcgctgctc tcggacggcc
     2041 gggcggcgaa ccgcatgatc gtgtcctacc gcacgatcat caagcagcgc acggccgagc
     2101 accgtcaggt gctgcacgcg ctggccgagg acagcgtccc ggccctgatg cactgcgcgg
     2161 caggcaagga ccgggccggt ctctccgtcg ccgtgacgct cctcgccctc ggtgtggagc
     2221 gcgaggccat cgtggcggac tacctggagt cgaacgcggc gcaccgccgc tacaaggtca
     2281 accgcagcag ctccgccgcc tcggcctaca cgcccgaggt gatggagctg ctcagcccgc
     2341 tcttcgacgc acgcgccgag tacctggcgg cggcgttcga aacgatcgag gagacatggg
     2401 gcggcgtcga cgcatatctg gaacaggcgc tcggcgtgac ccccgagaca cgggagcggc
     2461 tgcgggagcg gttcctcgac tgacccggcc cagcgcctct actgcccctt ggccccgagc
     2521 gtgaacagca ggtagatgaa ggcggcgaag acatgcccga ccgccacgta gatgatgagc
     2581 cgcacccaca gcccgcgcgg aatcttctcc tccatgtcct tcatgagcct tctcccgggg
     2641 tcgtcgtcga gggcgtcgag gtcatcgggg gcgccgaagc cgtcgccggt ccgaggcaca
     2701 gagcggccgt cggactctgc agcagggtgt gtacgaagag gagctcggcc ccgtcccggt
     2761 cggcggcggc gatccggtgc ggtgtcagcg agtcgaagtg ggcgctgtcg ccgggcgcga
     2821 ggacgtgcgc ggtgtccccg aggcgcagcc gcagctgccc ctggaggacg tacagccact
     2881 cctcaccggg atggacccgc acgatgtcgc cctgcgcccc gtacgggacg tgcacgcgca
     2941 gggactgcat accgcgtccg gcggcgccgg cctgccagta cgtccagcca ccggcccggg
     3001 tgggctccat gtcggcggag cgcacaacgg cgtcccgctc ggcgaccgtc tcaccgagca
     3061 gctcggagac ggtggtggcg tagatgcggg ccagcgcgag cagcatcggc agcgagggct
     3121 ggcgctgtcc ggtctccagc cgggagagat gggcgggcga gagcccggcg gcgcgggctg
     3181 cggactccag ggtgagcgcg gcgcggcgcc gcagcgcccg cagctggggg gcgacggcgg
     3241 gcagctgttc ctcggccgcc gccggctcgg acgggctcgt acccttggca gagttcatgc
     3301 ccttggcagg gttcatgtgt tccattgagc cgcaggcttg cctctgggac aaattccttg
     3361 cctcagaggc aaaaggtcgc ggccggcgcc cgcgaacccc ctaccgggcc ctgccgactc
     3421 ccatcggccc tctaccggcc cctaccggtt ggcgaccgcc tgtttgacca gtgtcttccc
     3481 gaagtcccac atcagcccgc ccccgctgtg cgcgtcgtcc atcacggcgg tgaacgcgtc
     3541 gacgaaccgg tccacgtccc gctcgccgac caccagcggc ggaatcagct tgatcacctc
     3601 cagatggtcg ccggagacct gggtgagaat ccggtgccgc tgcagcagcg gcacgaccac
     3661 catctgcgcg aacagtccct tgcgcgcggc ctgcagcatc gtccagcggc tgcgcagctt
     3721 cagcgatctg ggccgcccga actcgatgcc gatcatcagg ccgcgcccgc gcacgtcgct
     3781 gagcagttcg tacgtgtcga cgagcgccgc cagccgagtc ttgagctgct ctcccgtggc
     3841 gcgggcgttc gccacgatct gctcgttctc catgaccgag aggacggcga gcccggccgc
     3901 catggcctgc gcgttggccc cgaaactcgc ggagtgcacg aggacccggt ccatggacga
     3961 gtagaccttc ttgaagatcc agtccttgcc gagggtcgcg cccaccggca catagccgcc
     4021 ggacaaggcc ttcgcgacgc agaccaggtc cggctccaca ccgtcctcgt gctggtaggc
     4081 gtagaagtcc ccggtcctgc ccagcccggt ctgcacctcg tccgcgatga gcagcgcctt
     4141 gtgccggtgc agcaactcct gggcggcgcg cagatagccg ggcggcgact cgtgcacgcc
     4201 cttgccctgg atcggttcga cgatcaacgc ggcgacgtcg cccttcttca gctccgccgc
     4261 cagggcgtcg aggtcgccga gcgggaccgc cgtgtcgggc agcagcgggg cgaagccgtc
     4321 ccggaagccg tcctcgccgt tgacggacag ggacccggtg gtcaggccgt ggaaggcgtg
     4381 cgcgcagtac agcacgcgcg gtttcccggt ggcgtaccgg gcgaacttca gcgcggtctc
     4441 gacggcctcc gtaccgctgt tgccgaagaa cacccggtcc aggtgcgggc tgtgggcgag
     4501 cagtctctcc gcgaggagtc cgggcagcgg ctggcagtcg aagcgggtga ggtcggcgag
     4561 cccggcgtcg aggacgtcgt gcagtgcctt gcggacgacg gggtggtggc ggccgaggcc
     4621 catcaccccg aacccggcga gcatgtccag gtagtcgttg ccgtccgcgt cccagaagta
     4681 cgcgccctcg gcccgctcgt agaccttgtc gaagccgatg gtgtgcagca tgcgcggcag
     4741 ttggtggttc aggtacttcg cgtgcagctc gtagcgctcg gctccgcgcg cgtcgaggag
     4801 agcgccgagg tcgaactcct gggacttgct ggtcgtcatt ccggtttctc ctcggacgcg
     4861 tgcgccttgg cggccggctc accggcggca ctctgcttcc ccgtggcacc ctgtttcccg
     4921 gcggcctcgc cctccccgcc ggcctgcggc ccggcggcgc cccgccgacg ggccggcgtc
     4981 ttccgggcac gcgccgcggc tccccgccgc tcgggagcct cggccgtgtc cgcgggtccg
     5041 gcccccgcga cggccccgcg ggtctccccg ccgggatcgg ccttccgcga cccggcggca
     5101 cgccgcccgc cggtcggcgc cttccgcacg cgcttcgccg cggcccgccc gtcggcacgg
     5161 cctgcagcgg gaccggcgct cgaagaggcg tcccggcggg cgtccgggtg ggcgtccggg
     5221 gtgacggccc ggccggtggc ctcccccacc gtcaggctcg cgctgatccg gcccgcgatc
     5281 tcgacggggg tcagaccgat gtcggcgagc acctcgcccc gcttggcgtg cgcgaggaac
     5341 tgctcgggta tgccgaaccg ccgtacgggc acgtcgactt cggcgtccga cagggcgagc
     5401 gcgaccgccg cgcccacgcc ggcggcccgg ctgttgtcct cgacgaccgc gaccatgcgg
     5461 tgtccggcgg cgaggccggg cagcgcgggg tcgacgggct tgacccagcg cgggtccacc
     5521 accgtgcagc cgatgcccct ggccgccagc agctcggccg cgcccaggca caccggcgcc
     5581 atcacgccga cggcgacgag cagcacgtcg ggccgctcac cgcggtgcag cacgtccacc
     5641 ccgcccaccc ggtcgaccgc gggaatcccg ggtcccaccg actccttggg gaagcggatc
     5701 agcgtggggg cgtcgtccac ggcgaccgcc tcgcgcagct gggcacggag ctggtcggcg
     5761 tcgcgcggcg cggcgatcct gaggcccggc acgacctgga ggatcgacat gtcccacatg
     5821 ccgttgtgtg aggctccgtc agctccggtg actccggcgc ggtccagcac gaaggtcact
     5881 ccgcagcggt gcagcgcgac atccatgagg agctggtcga aggcgcggtt gaggaaggtc
     5941 gcgtacacgg cgacgaccgg atgcagtccg ccggtcgcga gcccggccgc ggacaccgtg
     6001 gcgtgctgct cggcgatgcc gacgtcccac acccggtcgg ggaaccgctc ggcgaacttc
     6061 gcgagcccca ccgggtgcag catggccgcc gtgatcgcca cgacgtccgc gcgttcctcg
     6121 ccgatgcgca cgatctcgtc gccgaacacc gaggtccagg aagggccgcc cgagggcgcg
     6181 agcggctcgc aggtgagcgg gtccatcaca ccgaccgtgt ggaagtggtc ctcctcgtgc
     6241 gcgagcgcgg gctcgtaacc gcgtcccttc tccgtcagac agtggatgag tacgggcccg
     6301 tggaagcgtt tcgcgcgccg cagggccgac tcgaccgcgc ccacgtcgtg cccgtcgatc
     6361 ggcccgacgt acttcagccc gaggtcctcg aacatgccct gcggggcgaa ggcgtccttg
     6421 aatcccttct tggcgccgtg cagcgactcg tagagcgtgc cgccgacgac gggtgtgcgc
     6481 agcaggacgt ccttgcccca ggccaggacc ttctcgtagc tgtcggtcgt gcgcagggtc
     6541 gccaggtggt tcgccaggcc gccgatcgtc ggcgagtacg agcgttcgtt gtcgttgacg
     6601 acgatgatca gtggccggtc cttggcggcg gcgatgttgt tcagcgcctc ccacgccatg
     6661 ccgccggtga gcgcgccgtc gccgatgacc gcgacgacgt gccccttctc cccctgtacc
     6721 tgccgggcct tggcgagccc gtcggcccag ccgagcgcgg tcgaggcgtg gctgttctcg
     6781 atgacgtcgt gctcggactc ctcgcgcgac gggtagccgg agaggccgcc cttgccgcgc
     6841 agcttggaga agtcctgacg tcccgtcaac atcttgtgta cgtagctctg gtggccggtg
     6901 tcccacagga tgcggtcgac gggcgactcg aagacccggt gaagcgcgat ggacagttcc
     6961 accaccccca ggttgggtcc cagatgtccg ccggtcctgg ccaccgcctg caccaggaac
     7021 tcccggatct cgtcggccag ccggcctatc tccgcctcgg acagcgcctt caggtcgcgt
     7081 ggtccccgga tgctctccag aatcgtcacg ctcgggcccc ctctcggtcc gtgctgtagc
     7141 taactcacgg tggcggcggc tgcttgcccc ggcaccgtga cctgcggctc gcctgacgcg
     7201 acgccgtccg cctccatctg ctcggcgatc ttcatcgcct cgtcgatgag cgtctccacg
     7261 atcttcgact cgggcaccgt cctgatgacc tcgcccctga cgaagatctg gcccttgccg
     7321 ttgccggagg cgactcccag gtccgcctcc cgggcttctc ccggcccgtt gacgacgcag
     7381 cccatgaccg cgacgcgcag gggcacctcc atgccctcca gaccggccgc gacctcgtcg
     7441 gcgagcttgt acacgtcgac ctgggcccgc ccgcaggagg ggcacgacac gatctccagc
     7501 cggcgctgcc gcagcccgag cgactccagg atctggatgc cgaccttgca ctcctcggcg
     7561 ggcggcgcgc tcagggacac ccggatggtg tcgccgatgc ccgcgctgag cagcgcgccg
     7621 aaggccaccg ccgacttgat ggtcccctgg aaggcgggac ccgcctcggt cacgccgagg
     7681 tgcagcgggt agtcgctctg ggcggccaac tgccggtagg cgttgaccat cacgaccggg
     7741 tcgttgtgtt tgaccgagat cttgatgtcc ctgaaaccgt gctcctcgaa gagcgaggcc
     7801 tcccacagcg ccgactccac cagcgcctcg ggcgtggcct tgccgtactt ctggagcagc
     7861 cgccggtcca gcgagccggc gttgaccccg atccggatcg gcgtgccgtg gtccttcgcg
     7921 gcccgcgcga tctccttcac cttgtcgtcg aactgcttga tgttgccggg gttcacgcgc
     7981 accgcggcgc agcccgcctc gatcgcggcg aacacgtact tcggctggaa gtggatgtcc
     8041 gcgatcaccg ggatctgtga cttgcgggcg atggtggcca gcgcgtccgc gtcgtcctgc
     8101 gtggggcagg cgacgcggac gatctggcag ccggacgcgg tgagttcggc gatctgctga
     8161 agcgtggcgc cgatgtcgga cgtacgcgtc gtcgtcatcg actgcaccga cacgggtgcc
     8221 ccgcccccga ccgccaccgg tccgacctgg atctgccgcg agacgcgacg ctccgcgatc
     8281 ggccggaccg gtacctcggg gaggcccaag gagatggcgg tcacgacgtc acccgcggtt
     8341 tcccgagacg gtctcacggg cggcccgcag ggactccttg agggagccca tggtggccag
     8401 gaccgcggtc ggctcgtagc cgcagtgcgc catgcagttg gcgcagcgcg ggtccttgcc
     8461 gcggccgtac gagtcccagt cggtgtcctc gatgagttcc cggtacgtcg tgacgtaccc
     8521 gtcgctcatc agatagcagg gcttctgcca gccgaagagc gagtagttgg ggatcgccca
     8581 cgccgtgcag gggaagtcga ccttgccctc caggaagtcc aggaagagcg gggagtggtt
     8641 gagccgccag cggcgccggt tgccgcccga gaacgccttc ttgaacagtt cgcgggtctg
     8701 ctcgacaccc aggaagtgct cctggtcggg cgccttctcg taggcgtagg cgggcgagat
     8761 catcatctcg tccaccttca ggtcgtcatt gaggaagttg agcacctcga tgatcgtctg
     8821 cggggtgtcg gtgttgaaga aggtcgagtt ggtggtgacc cggaaaccgc gcttcttggc
     8881 ttccttgatg gcggccacgg cctcgtcgaa cacaccctcc ttggccacgg actcgtcgtg
     8941 ccgctcccgc agtccgtcga tgtgcacggc gaacgcgaag tacggggagg gcttgaactt
     9001 gtccatcttc ttgcgcatca gcatggcgtt ggtgcagagg aagacgtact tcttacgggc
     9061 caccagctgc cgtacgatct cgtcgatctt cgggtgcatc aggggctcgc cgccggcgat
     9121 ggacaccatc ggcgccccgg actccagcac cgccccgacg gcctgcgcca ccggcatgcg
     9181 ctgcttgagc accccggccg ggtgctggat cttgccgcag ccctcgcacg caaggttgca
     9241 ggcgtagagc ggttcgagct cgacgatcag cggaaacttc tcccgcttgc ggagtttctg
     9301 ttcagcgaga tacgtcgcga ccttgatggt ctggcgcagc ggcatggcca tctggctcac
     9361 ctccggggga gcagcaggga acggtgccat tcgaaaaaaa caggaaggac ggcacgaaga
     9421 acgcggaaag ccgatattcc accgcgcacc gtgccgatcc ggacgagttc atgttctgga
     9481 gcgtccacga ccacccgtac ggccgcaacc ggacgttcgc cggcgcggac ggcgctgtgg
     9541 agcgtggccg ccgactccat gtcgaccgcg atcgcgccgg tcgcgagcag agccggccgc
     9601 tgcggaccgc ggacgacgtg gtcggaaccg gtgagcggtc ccgtgtggac ggtgcgccct
     9661 ggcagggcgc gcgtcagctc cttgacgagc aggtcggtgc cgacgcacgg cgtggtgccg
     9721 tgcgggcccc gggtctcctc ggcgacgacc aggtctcccg ggtgcatacc gggggcgagc
     9781 ccggcacaga agcccgtggc caggacggcc gcccggctga gtgccggtcc ggccagtgcc
     9841 ctgccgaccg cccgttcggc ggccagcggt cccatgcccg tacgcagcac ggtgaccggt
     9901 ccttcggcgc cgccccggtc gccgccggtg cgcagggcca gtcgctcgat gccgagcgcg
     9961 caggcgatca gcagcggggc ggcgcccggt gtcgcgctca tcagctcgcc ctgccgaagg
    10021 aactctggga gctctgcagg ccggcgaacg gttcgccgtt gacgtaccgg ccgagcgcgg
    10081 tgagcgggaa cacctgccgg tagaggtggt agttgatcga gaagtcccac gggaacccgg
    10141 tgccggtgaa gtacggctcg tcccaggagc cgtccgccag ctgggtccgg gcgagccagg
    10201 cgacgccgcg ctcgacggcc ttggagtcgt gctccccggc cgcgagcagc gccagcagcg
    10261 cccacgcggt ctgggaggcg gtcgactcgc cccgcccgct ccactcggcg acgtcgtggt
    10321 aggagcgcag gtcctcgccc cagccgccgt cctcgttctg tacggtctcc agccaggaca
    10381 cggcccggcg gatcgcgggg tgcgagccgg gcagtccggc ggcgaccagc gcgggcacca
    10441 ccgaccccgt cccgtacacg tagttgacgc cccagcggcc gaaccaggaa ccgttctcct
    10501 cctgttccgc gagcagccac tcgatgcccc ggcgggtgcg cgggtcgtgg gcgagcccct
    10561 cgaccgcgag catctccacg acgtgcgcgg tgacgtcggc ggacggcggg tcgatgacct
    10621 cgccgaagtc gcagaacggc agccgattgg ggaaggggct ggtgttgtcg acgtcgaagg
    10681 cgccccacgc gccgttcttc gactgcatgc cgaggttcca gcgcaccccg cgtccgatgg
    10741 ccttctccac ccgctccggg tcgtggtgct tgacgcggcg cagcgcgagg accacctctg
    10801 cggtgtcgtc gatgtcgggg tagttgtcgt tgtggaactc gaacgcccag ccgccgggcg
    10861 agagttgagg ccttttgacc gcccagtcgc cggggcggac gatctcctct ccgagcatcc
    10921 agtccgcggc cctcaccagc tgcggatgat cggcgggcac gcccgcgtcg gcgagcgcga
    10981 tggtcgcgag acaggtgtcc cagaccggtg actgacaggc ctcgatcatc cgggccccgt
    11041 cctcgcgcca cacggcgaag cggtccaggg aggccagtcc ctcgcgcatc accgggtgtt
    11101 cgaggtcgta gccgagcagg tacagggcga tgaccgagta gacggcgggc ggctggatgc
    11161 cgccccagca gccgtcgttc tcctgacgct cgatgatcca gcggcccgcg gtgttcatcg
    11221 cggccctgcg gagcctgcgc ggcgcgacct tgcggtacgc gtgcagggcc cggtcgaggc
    11281 gctggaacac cccgtcccaa ctcgccaccg gggcgaaggg cttgaccggg ttggggtcgc
    11341 gggggtcggt gtgcagctcg tccagcgcga agggcgcggg gcgcaccggg cgcttcgccg
    11401 agacgacggt gagcggcacg atggtctgcc gggcccagca gccgaagtcg tagatgttga
    11461 gcggcgccca cttcgggaag tagatgagtt ccggagggag ttcggggagg tcgtcccact
    11521 tccaccagcc gaacagggcg agccagatcc gggtgaagac acgggccgcg gcgatgccgc
    11581 cccgctcccg gatccacgcg gcggcccgcg ccatgtgcgg atcgtccggc gcgtcaccgg
    11641 caaggcgcag ggcgacgtac gcctcgacgg tggtggagag ttcgcccggt ccgccgtaga
    11701 aggaggccca ggtgccgtcc tcgcgctgct cgccgcggat gaacagggcc gcggcgtggg
    11761 tggtcttctc gtcgtcgatg cccaggaact gacggagcag caggtcttcg gcgtccatgg
    11821 tgacgttggt ctccaggtcg cccttccacc atccctcggc gtcctgcgtg ctcagcagga
    11881 agccggtggc gcgctgtatc gcgcgcgcgg cggcgtctcg gacatcggct gtcccggctg
    11941 ccgcgggagt cgattctgta cggatgtcgc tggccgaggc agcgcggggc ggcagtgctc
    12001 cggtgcttcc gtcggtcgtc gctgtcatgg cttccccttc gtgcagtggt gtgtctctgc
    12061 tgtgggtccg ccgtcggccg gtgcgcgtga ctgcgcagca ccggccggcg actacgcgag
    12121 gtgtattcga ccgatagtga tcatctcttt cgtacgacga cgaagtcggc gagctccacg
    12181 aactgggctc gtacctgttc gggcatatgg atggtgtcga gcgcctcgac ggcgacggtg
    12241 tgctgccggc gcgcctcctg cgcggtccac tcgcggccgc cggcctcctc gatgagcgcg
    12301 gcgcgtgcgg cgaactcctc ctcggagaag ttctcgaagt cgctcctctt ggcgtccgcc
    12361 gcgagcagtt cgccgagccg ctcggaggcc gggccgcccg ccgcgagcgc ggccacgacg
    12421 ggcagggact tcttgcgctg gcgcaggtcg ctccaggtct gcttgccggt ggccaccggg
    12481 tcgccccaga tgccgagcag gtcgtcgacg gcctggaagg cgaggccgag gtggtagccg
    12541 tacttctcca gcgtgtcggc cgtgcggtcg tcggcgccgc cgaggaccgc gccgatggag
    12601 gaggcgcagg cgagcagggc gccggtcttg ttgccctcca tctccaggca ctcctcgacg
    12661 ctgacgcggt cgcggtgctc gtaggagatg tcctgggcct ggccgtcgat cagcgcgcgc
    12721 gtggcggtgg tgaggcggcg ggtggcacgg cccgcctcga ccgtgccgat ctccaggagc
    12781 agttcgttgg ccagcgcgaa cagggcgtcg ccgacgagga tcgcctgggc ggggccgtgc
    12841 accttccaga cggtgtcgcg gtgccggcgc tgctcgtcgc cgtccatcag gtcgtcgtgc
    12901 aggagcgaga agttgtgcac cagttcgacg gcgaccgcgc ccggcacgcc cacctcgggg
    12961 gcggcgccgg cggcctgggc ggacagcacg gcgagggcgg gccgtacggc cttgccgccg
    13021 tcgccgtcgg cggggttgcc ctcggcgtcg atccagccga agtggtaggc ggcgaccgtg
    13081 tccatgggag gtgcgaggcg gtcgatggcc gcccgcagta ccggtgaggc cagggtccgg
    13141 ccacgctcca ggagcgcggt cacgtccacc gcgtcggcag ccttcgatgc cgggggcaca
    13201 gtgggcacag tctctcctct atttgcgata cggggggtgc gggcaccggt ccccgcgctc
    13261 tgatcgagcg tcacgccgcc tcctcgaaga gctcgacgag gtggtcgcga ggccggccca
    13321 gggcgtcgag cgccgcgtcg gccgcgctca cgccgctgcg gaccgcactc tccatggtcg
    13381 cgggccaccc ggtggcggtc cacgcgccgg ccaggtacag gccgggtgcc tcggtgcggg
    13441 cgccgggccg cagccggccg acgccggggg ccggagcgaa cgtcgcggtt cgctccctgg
    13501 tcacgaagaa gtcctggacc gccgcgtccc gggcacgggg cagcagtcgc tccagctccg
    13561 gcagataccg ctcgcgcagc gccgagacgg gttcgtcgat ctcgtcctgc gcgaccgact
    13621 gggacagcgc gaggtactgg ccctccttga gcccggacgc ctcggtccgg tcgaagaccc
    13681 actgcaccgg ggagccgagg gcggcgaaga acggccggct gagcaccttc cggtcgtaca
    13741 cgacgtggat gttgaggatc ggcgccgtac cgatgtcgag cagccgctcg ggggcgtcga
    13801 gtgcgccctc gggcagcaga tcgtgggcct cgcgctgcgg tacggcgagg acgaccgcgt
    13861 cggcgtcgag cgtttcgccg ggaacctgaa cgcgccaacg cccgttctcg tgtggggaga
    13921 tggatccgtc ttggtggatg ggtccgggtc gggagatgga ggtgacgcgt gtacggactt
    13981 cggtacggac tcccgcggag tcgagcgcct tgcgggccag ccggtcgtgc agttcgccca
    14041 gggggacgcg cgcccagccg atgtcggccg cgcccggggc ggagagcaga ccggtcttga
    14101 acaccatcgc ggcgaggccg agcgacgcgt cgccggccac cgcgttgagg gtggcgaccc
    14161 ccaccaggtc ccacagtgcc tcgatggccc gctcggactg accgtgcgcg gccagccagc
    14221 cgccgaagct ctgcgtgtcg agcgccggat cggcgaggtc gagtctcttg agcgccagtg
    14281 cggcacggcc gaccttggcg cgctcggcga gcgacagatg cgggtaggtc gcgaggctgc
    14341 gcgccagatg cagggggacg ggcagcgccg tccggccgat tctgccgagc cgtcgtccgg
    14401 gtttcgcccc ggcgtccagg accggcacgt cgagccgggc ctgcagcggc gcgaggtccg
    14461 ctccgtcgac gcggccgagg aaccagcggt aggccgtgca gcagcgcagg tacacatgct
    14521 ggccgttgtc cacggtgagt gcgtcacgct ggaaggagaa ggcgagcccg ccgaggcggg
    14581 gccgcccttc gagcagcgtc acccgcactc ccgcgtcggc cagcgcgagc gccgcggtga
    14641 tcccggcgag ccccccgccg accaccacgg ccgtcgcggg gcggctcgcc gagtcggcgt
    14701 cgaggccctc gtcctgtgag gcgtcgttca tcgtgcacct tcccccgcgg cctcgccgtg
    14761 ccggtggaac gggacacggg cggccgtcga agtcagggac gcggcgtagg ggcggagggt
    14821 tgcgcaccgc ttccaggcgc tcggttcgtc ttgtccgtct tgtctgtctt gttcgtcctg
    14881 gaccggagtg tccatcaagc gcgcctcctg atggtgcggc gggagacgtg ccgggcgtcg
    14941 agtccggaca ggccccgcac ggcgacgtac gccttctcgc gtccgggcag tgagacccgg
    15001 ccgcgcagga cggcctccgg gtcgcgctcg atgcggtcga ggaggcggcg gtagatgccg
    15061 gccatcgcgg cgacgcaggc gccgctgcgg cggtccagca tcggcagcag gcggtagccc
    15121 tccgcgaaca gcgcgcgggc ccggcgcact tcgaagtgca cgaggcccgc gaagtccgag
    15181 ccctccggtg gccgcggccc gtcgaacccg gccgagcagc cgaacttcgc gaggtcgtcc
    15241 gcgggcagat aggtacggcc gccctcggcg tcctcccgaa cgtccctgag gatgttggtg
    15301 agttggagcg cgagcccgag cgtgtccgcg tactccggcg cccgctcggc tccgcgcgcc
    15361 cccgattccg taccgaagac gccgagcgag agccggccga tggcgccggc gacgcagcgg
    15421 cagtagacct tcaggtcgtc ccaggtctcg tacgtctcgc cgcggacgtc catgaggacg
    15481 ccgtcgatga gttcgtcgag gccgtcgagc gggaccggga agtggtccgc cgtgtgccgc
    15541 agcgcgacgg cgaccggatc ggtgtcgtcc tcgtccaccg cgcggtcccg gatccgggcg
    15601 agcagcaccc gggtctcctc aagccgcgcc gccttgacct cgggggcgag cgcgccgtca
    15661 ccgatgtcgt cgacgcgccg tgagaacgcg tacagcgccg acatggcacg cctcttcggc
    15721 gtcggcagca gcctgatgcc gtacgcgaaa ttgcgggcct gctgcccggt gatggcctcg
    15781 cagtagccgt atgcggcgag taccggtgcg gacatgtgtg gttccgactc cacggtccgg
    15841 atcacccctt tcctcgcaga gtcactccca cctcgcgcag caactggatc ttgccgggct
    15901 tcggcgggcc gggaagtacg tcgtattggg cggcggcgat cgcccggatc gccgccctcc
    15961 ctcctgccac gaaccccgcg agcagcagct tcagcctgcc gtggacgcta cccacaaggg
    16021 gggtgccttc attcaggagg ttcccggcgc gttctgtttc gtatgcaacc agtgcgcgcg
    16081 ccgatgcgcc tgctgtggcc gtggcgagat ccgcctcctg gacgtgaaag cgcttcatgt
    16141 cctgggcggg aaggtagatg cggtcgcggc cgaggtcctc ggcgacgtcc tggaggtgct
    16201 cgacgatctg cagggccgtg cagacggcgt cggagcggcg gacccgctcg ggggtcgagg
    16261 taccggtgac ggagaggacc agacggccga ccgggttggc ggacagctcg cagtaggcga
    16321 ggaggtcgtc gtaggtctcg taccgcttga cgatctggtc ctggcggttc gccgcgatca
    16381 ggccgaggaa gggctcgggg atcaggccgg tgcggcggac cgtcggctgg agccggcgca
    16441 ggagcgggtg gccgggagtc gagtcgaaga cccggtgcag atccgcctcg aaggcgtcga
    16501 gcaggacgag ccggtcctcg gcctcgtcgg gcgagacgcc caggaggcgg gcgtcctggc
    16561 cgccgggggc caggtctccg tcgccgatgt cgtcgacgag ccgggcgaag ccgtagacgg
    16621 ccatgaggtc ggcgcgccag gccctgggca gaaagaacgg cgccacggga aagttctcgt
    16681 ccgcggcctt gtcgagggtg ctgcgctccg ggtcaccggc gcgcgccgtg ccggctggcg
    16741 tcatcgctcg ctgcccgggc cgggagcggt ggacccgcag acggcacacg cacagcggcg
    16801 ctggagagtt tccgtagcca ttgccgtcac atctcccgtt ctacactgcc gacccaatac
    16861 tgcccatttc ggacacgccg cccggttgtc cgcgcagcag acccctctcc gggcgtcgcg
    16921 cattatcgcc ccacttgccg cgaatcagca ccggtacagc ttacgttgta caacccggca
    16981 cgcctcgtcg gggtgtcccg cacatcacaa gaacacaccg attggcgtca agattcctaa
    17041 ggacgccgag agttggctct tcctttgcag acgcagggcc ccgtcgaacc gttccgacgg
    17101 ggccccgagt gctgtcacgc gatgcgggct acttgcccgt gaacttctcg tactccttca
    17161 gaacctcgcc ggtcgggccg tccaggcgca gctcgccgcg ctccagccac aggacgcggt
    17221 cgcaggtgtc acggatcgac ttgttgttgt ggctgacgag gaacaccgtg ccggccgatt
    17281 tgcgcagctc ccggatccgg gcctcggagc gcttctggaa actgcggtcg ccggtggcga
    17341 gggcctcgtc gatcatgagg acgtcgtggt ccttggcggc cgcgatggag aagcgcagcc
    17401 gggcggccat gccggaggag taggtgcgca tgggcagggt gatgaagtcg cccttctcgt
    17461 tgatgcccga gaactcgacg atgtcctggt agcgctccct gatctgctcc cgggtcatac
    17521 ccatggccag gccgccgagg atgacgttcc gctcgcccgt gaggtcgttc atcagggccg
    17581 cgttgacgcc gaggagggag ggctggccgt cggtgtagac gtggcccttc tcggcgggca
    17641 gcagtccggc gatggcccgc agcagggtgg acttgccgga gccgttggag ccgatcaggc
    17701 cgatggcctc accgcggtag gacttgaagg agacgccgcg gacggcgtgc accttgcgga
    17761 cgccccgctc ctcgccgcgc ctgacgatgc ggctgagggc ggaggtggcg ctgcccttgc
    17821 cggtcctggc gccgttgacg cggtagacga tgtgcagttc gtccgcgatg acggtcggga
    17881 tcgtgctccc ggtgttctgc tcagccacgg ccgtaacgct cctcagcctt ccagaagtac
    17941 acgaatccgc cgacggcgac gaggacggcc cagccgcccg ccaccgccca cacgtgcggc
    18001 ggcaggttct cggagccgta gccgtcgacg agcgcgaagc gcatcaggtc catatagatg
    18061 gcggccgggt tccactggag gatgtcggcg atccacgcgg ggtgctcttc gagcatcacg
    18121 gggatcgaga acatgacccc ggacgcgtac atccacgtac gcatcacgaa cggcatgagc
    18181 tgggccaggt ccggggtctt ggaacccatc ctggccatga tcatcgcgag gccggtgttg
    18241 aagaggaact gcagcacgag gaccgggacg atcagcagcc aggacagctg gggatagctg
    18301 ccgaagccga ccgccacgac gaacagcacg atcatcgaga agagcagctg ctggagctgc
    18361 tgcagcgaga acgagatcgg cagcgcggcg cgcgggaagt gcagcgcccg gaccaggccg
    18421 aggttgccgg agatcgcgcg cacccccgcc atcaccgaac tctgcgtgaa ggtgaaggtg
    18481 aagacacccg tcaccaggaa cgggatgtac acctcccggg acatgccgcg gtcggccttc
    18541 aggatcaggc cgaagatcag gaagtacacg gccgcgttca gcagcggtgt ggccacctgc
    18601 cacagctggc cgagcttggc ctggctgtac tgggcggtga gcttcgcctg cgagaaggcg
    18661 aggatgaagt gacgccgtcc ccagagctgg tgaacgtact cgacgaggcc gggccgggcg
    18721 ccgctgacgg ccagcccgta cttggcggcg aggtccgccg cggtaagccc gtcatcgggg
    18781 gacggagggg cgctcaccgc gacgccgccg tcatgcgttg tctcactcac aagggaaact
    18841 ttcgtcctca agatgcgcgg cctggtaggg cgtaggccaa agacagggac cggggtacgg
    18901 cccgaatgct ctcagatatc gagcttgtca gatgacgggt ggccggccca gtcgggtcag
    18961 gcgccatacc gtacgccact tcatggggcg ccggggcccg cacggactgg tccagccctc
    19021 cttgaaaccg ccgaaccagg cctgcagggc cgggcgcgag gggcgacggg cgagcgtgag
    19081 cagcatccac acgccgaggt acacggggac cagcggcgcg ggcaggttcc ggcgggcgag
    19141 ccagacgcgg ttgcgggcga ccatccggtg gtagaccgcg tgccgcgagg gcgcggtcgt
    19201 ggggtggttc agcaccatgt ccgagcggta gtcgatcatc cagcccgcgt cgagggcccg
    19261 ccaggcgagg tcggtctcct cgtgggcgta gaagaactcg tcgggcagcc cgccgacctc
    19321 ggcgagcacc ttcgtacgga ccgcgttggc gccgccgagg aaggtggtga cacgggagtt
    19381 gcgcatcgga tcggaggcgc gcagccgggg cacgtggcgg cgctgggtga tcccggtctc
    19441 ggggtcggcg atacggaagc tgatgatgcc gagttccggg tcggccgcga aggcctgccg
    19501 gcagagttcg gcggtgtcgt ggtgggcgag gaggccgtcg tcgtccagga agagcaggac
    19561 gtccacgtcg gtgccgccgg ggccgaacgc ctcgatgccg acgttgcggc cgccggggat
    19621 gccgaggttc tccggcagtt cgaccgtacg gagccccggt gcggaccccg cgacgtccgg
    19681 gacgggcgag ccgttgccga ccacgaccac ctcgaccggg tcgccgtcct gcttggcgac
    19741 cgagtcgagg agggcacgga gctcgtcggg gcggttgccc atggtgatga tcaccgcgcc
    19801 gaccctcatg gccgtgctca cttcagcctg ctcgacgcga ggatggacac caggtgcagc
    19861 acggtctgca gcaccgcgat gccggccagg accgcgacgc cgagccgcga gaagaacagg
    19921 tcgtcccgaa ccgtgtccag gaccgcgagg accaggatga gcagggaggc ctctatgccg
    19981 aggacgagcc ggtggaactt cagcgcgccc gcggcccggc gggccagcgc catgccggag
    20041 gagcgcggct cggaggccga ctcctggacc ggcgccttgc ccgtctggtg gcgggcgaca
    20101 ccgacgaggt cggtctcgga cttgatcagg acggcgccga gggcggccag ggtgccgagg
    20161 aaggcccaca gccagtcgat ccgcccggtg ccccacagat cggcggcgcg cagaccgaag
    20221 ccgaccagga cggcggcgtc gcacaggtag gcggcgacgc ggtcgacgta caccccggtc
    20281 atcgagtact gcttgcgcca gcgggcgagt tcgccgtcga cgcagtcgaa cagcaggtac
    20341 agctggacca tgagcacgcc gagcacggcg cccgggatgc ccggcaccag cagggccggc
    20401 gcggcgagca cgccgaagac ggtcatcacg taggtcagct ggttgggcgt gaccttggtg
    20461 ttcaccaggt gccggtcgat gcgcagcgag atctcgcgca tgtagagccg gcccccccag
    20521 tgctcgccgc tgcgccggtc cttcacaccc ggcgggtgga cgaccgggcg gagctcagct
    20581 accgatggct tttgcatagt cggcgtatgc gtccctgatc tggtcggtgg agagagcgag
    20641 gtgttcgagg atggtgtagc ggcccggccg ggtgctcgga gcgaactcca cgacctggac
    20701 gaactcgtcc ggggtgaagc cgatctcctc cggcagcacg ggcagcccgt ggcggcgcag
    20761 gacctcggcc atgtacgccg actcctcgcg ggcaccgcgc aggtgcatcg cgaaggccgc
    20821 gcccagaccg cactgctcgc cgtggctggc ggcgcgcttg gggaagagca ggtcgaagcc
    20881 gtggttgatc tcgtggcagg cgccggacgc cggacgggag tcgcccgcga ccgacatgga
    20941 gatgccggtg aggaccaggc cctcggcgag cacctggagg aagccgtcgt cgccgacgcc
    21001 gcccgggtgc cgcagcacgg cctcgccggc ctggcgggcc atcgcggcgg cgagaccgtc
    21061 gatcttctcg cccttctcgc ggttggccag ctcccagtcc gcgaccgcgg agatgttgga
    21121 cagggcgtcg ccgatgccgg agcgcacgaa gcggaccggg gcctcccgga tcacgtcgag
    21181 gtcgatgacg acggcgatcg ggttcggcac cccgtacgag ccgcggcccg cgtcgttgtc
    21241 gagggtcgcg accggtgagc acagaccgtc gtgcgagagg ttcgtggcga cggcgaccag
    21301 cgggaggccg atccgggccg cggcgtactt cgcgcagtcg atgatcttgc cgccgccgag
    21361 gcccacgacc gcgtcgtagc gccccttctt catggcgtcg gcgagcttga tcgcctcgtc
    21421 cagggtgccg ccgccgacct cgaaccagtc ggcgcccggc atcgcggggg ccaggcgttc
    21481 gcgcagcttg gcgcccgagc cggcgctgat ggcgacggcc agcttgccgg agtgcgagat
    21541 gcgctggtcg gcgaggacgg ccgcgaggtc gtccagggcg cccggacgga tgtcgacgac
    21601 gaccggcgag gggatgagcc tcgtcagtac tggcacgcga tctcacgtcc cttggcgagg
    21661 tcgtcgtggt tgtcgatctc gacccacttg acgtcgccga tgggggccac gtcgatacgg
    21721 aagccgcggt tcacgagctc ctggtagccg tgctcgtaga actgctgcgg gtccgcttcg
    21781 aagacggtct tcagcgcgtc ggccagttcg tcggccgcgt cgccctcgat gagggtgacg
    21841 ccgatgtact caccggtcgc ctcggccggg tccatcagct tggtgatctt cgtcatgtcg
    21901 ccctcggggc cgacgacgac cttcatctcc tcgtcggcga gggacttcac cgtgtcgagg
    21961 gcgaggatga tcttcttgcc gtcgccgcgg gcggcgagca gggtcttctc gacggagacc
    22021 gggtgcacgg tgtcgccgtt ggcgaggatc accgagtgct tgatcgcgtc acggccgcac
    22081 cacagggagt aggcgttgtt ccactcctcg gccttgtcgt tgtcgatcag ggtgatcttg
    22141 acgccgtact tctgctccag cgcctcgcgg cgctcgtaga cggcttcctt gcggtagccg
    22201 acgatgaccg cgacctcggt caggccgatc tcggcgaagt tgccgagggt gaggtcgagc
    22261 acggtgatgc tgtcctcatc gtcggcggca ccttcgggtc cgaccggcac cagggccttg
    22321 ggcaggacgt cggtgtaggg acgcagacgc cgtccggcgc cggcagccag cacgaggccg
    22381 atcatgcggg ttctccttca tcgtgtacgg cgggagcgcc gcgcctgtgg gcggtcaccc
    22441 agtagcggat gctctcgaag agcaccagca gtgccacggc cacggcgaga accgtgagcg
    22501 cgaccttgaa atctgtggcg gtgagcagcg cggccaggac ggcgaccagc agcgtcctgc
    22561 cttcgtgccc gccgatcgcc cgcaccagcc agtgcggcgg cgcgcctgcg cccccgcgga
    22621 tgcggtacac cgtgtcgtag tgatggtagg cgaccgcggc caccagcccg aaagctgctg
    22681 gaagggcgcc gttcacatcg gccttggccg ccaggatcag gacggtgccg tattcggtgg
    22741 cgcggaagag cggggggagc agccagtcga gggggccctt gagggggcgt gcgacgacgt
    22801 cacccgacac caggacatac gcgacggcgc acacgacagt cgaccagccc ggtccgtcga
    22861 tccaggccgc gaggaccacg acgacggcac cggccagggc gagaagccgg gccaggacgg
    22921 ggagagggct cggtatgacg cgtgccagcg actccgccag gggcccgctg tccgcgaggt
    22981 ccgccagcgc ccgcgcggcc tggtccgtcc gctgtgcccg gcgggtcagc gagcgcagca
    23041 cccggccggc ggtggtgtag caggcggcga aggcgcagcc gacgagcagt acgtagaagg
    23101 tgatgcgggg cgtcgtgagc gcggtgagta ctgcgatcat cgcccagcgc tcgccgatgg
    23161 gcaggacgat catccggcgc agccagaccg tccagccgac gccgtcgagc cggtccgaaa
    23221 aagcggccgt ggggctggag ttggcggtgg cacccgggcc cggcgtgctg ttgacgttcg
    23281 cctcgttgaa ggagaagtcg accacgtgcc ggcaggtctg caggaccatc gcgccgaggg
    23341 ccagcgccca tacgtcgtcg ccgccgcggg cggcgccgag ggcgaggccc gcgtagtagg
    23401 cgtactcctt ggcccggtcg aaggtcgcgt cgagccaggc gccgagcgtg gagtactgca
    23461 gggagtagcg ggcgagctgg ccgtccgtgc agtcgaggac gaaggagcac aggagcagca
    23521 ggcccgcggc gacgaagccg gccctggtgc cggtcgccgc gcagccggcc gcgatcagcg
    23581 cggtgagcag cgacgccgtg gtgacctggt tcggggtcag gccgcggcgg gcgcaccacc
    23641 gggcaatgta gcgggagtac gggctgatgc agtacgtggt gaagaagccg tcccgcgact
    23701 tcaccgccgt acgcagccgg atcgcctcct cgtccaccga ggcgacggcc tgccgggcct
    23761 cgttgcgggc ctgtgggtcc ctggggacct cggcgacgag ttcgcccagt tcggggcggt
    23821 gcaaatcggt gtcgagggcg tccgcgacgc ggtcggtgac gatgccgacc accacggagc
    23881 cgttcgacgc gtccgtggag gcggtgcgca gcgcccggcc gagcgccgca cgcgccgcgg
    23941 gcttggcggt gacggcgccg gggatcgcgg cggcgtcgaa gcgggggtcg gtcaggccga
    24001 gccgcagcgc gtggacgtgc cccacgaagc gggcgtcgac gacggcgacc cgctggtccg
    24061 cggggacggc cgcgaggagc gtctcggcgt cggccgcgtc ggcggcggcc cgcacgtcgt
    24121 agccgagcga ccgcagatcg ccttcgagcg acgacccggg gaccggctga ccggtgagga
    24181 tggcggtcga cagacgaact cactcctctg ggttccggcg tacgcgacgc cgggcatgtg
    24241 cgtggtgggg gtgcgccccg ggccaactac ggccgggcgg cacgtcggca gaggctatcg
    24301 gatgatgaga agcagccgtt caccggccgt tcacggtccg atcaacagga tctgatcggc
    24361 gcgcccgcca cgatcatcat cgtggattcg ggcccccgcc cacaaaccgc ggcccattcc
    24421 ggcgcaatcc acggcatagc tcccgcgccc tccgaaagga ctgcggaccc ggcatagggt
    24481 gggcgcccat gacatggctg atcacaggtg gagctggata catcggggcg catgtggcgc
    24541 gggccatggc cgaggccggg gagcgcgtgc tcgcgctcga cgacctctcg gccggggttc
    24601 cgtcgcggct gcccgagggg atcccgctcg tgcagggttc gtccctcgac ggggagttgc
    24661 tgaagcgggt cctcgccgag cacgcggtga cgggtgtggt gcacctggcc gcgcgcaagc
    24721 aggtcggcga gtccgtggcc cagcccgcgc gctactacca ggagaacgtc ggagggctcg
    24781 ccacgctcct ggacgcggtc gccggggcgg gtgtggagcg tttcctcttc tcgtcgtccg
    24841 cggccgtcta cggcaacccg gacgcggaac tcatcacgga ggacactccg tgcgccccga
    24901 tgagtcccta cggcgagacg aagctcgcgg gtgagtggct ggtgcgggcc gccggccgcg
    24961 cgcacggcat caggaccgtg tgcctgcgct acttcaacgt ggcgggcgcc gccgcgccgg
    25021 agctggcgga caccggcgtc ttcaacgtgg tcccgatggt cttcgaccgg ctcacgcgcg
    25081 gcgaggcccc ccggatcttc ggcgacgact atccgacgcc ggacggcacc tgcgtacgcg
    25141 actacatcca tgtcgccgac ctcgccgagg cacatctcgc agcggcccgg cggctgtcct
    25201 ccgcggacgc cgcggacggc gcgggcgatc tgacggtcaa catcggccgc ggcgagggtg
    25261 tctcggtgcg cgaactcgtg acgctcatcg gcgaggtcac cggcgacacc cgtccggtgc
    25321 gcgtcgagcc gcgccgcccg ggtgacgccc cgcgcgcggt cgcctcggcg gcggtggccg
    25381 ccggcgaact gggctggacc gcgcggcgcg gggtgcgcga gatggtcgag tcggcctggc
    25441 ggggctggca gctgcaccac gcgtgacaca gtgcgtgaca cgtggacgtg gacgtggacg
    25501 tgagggacgc gaacgtggac ggcccggctt ccgggtggga ttcggactgg cttccggccg
    25561 gcgccgggcc cggttcaccg ctgcgggtga agtacggata gctcccgttc tggacggttc
    25621 cgtaccggta gcggcgggaa cgatggggtg tccggcccct ttcggcgtcc ggtcggcaca
    25681 gggcgtgatg tccggttcgg ccgcgcggcg gaaccggatg cgcgggaccc gcgtggtgcc
    25741 gggagtgccg gttcggtacg gcagacttgg ggctcgaaga ccgatgcgaa ggacgggtat
    25801 gccgatcact cctgccaccg cgacgcacag ttcgtcgaac ggcgccgctg aagccatctt
    25861 gctcgaactg gtcgacgagg acggcgtcac gatcggcacg gcggagaaac tcacagctca
    25921 tcagccgccc ggtcagctgc accgggcgtt ctccgtcttc ctcttcgacg agcggggccg
    25981 gctgctgctg cagcagcggg cgctgggcaa gtaccactcc cccggtgtct ggtccaacac
    26041 ctgctgcggg cacccgtacc ccggcgaggc ccccttcgcg gcggccgcgc gccggacgta
    26101 cgaggagctg ggagtctcgc cgtcgctgct cgccgaggcg ggcacggtgc gctacaacca
    26161 cccggacccg gcgtcggggc tggtggagca ggagttcaac cacctcttcg tcgggatggt
    26221 gcagtcggct ctgcggcccg accccgagga ggtcgggtcg acggccttcg tgagcgcggc
    26281 cgagctggcc gagcggcacg cggcggaccc gttctcggcg tggttcatga cggtgctgga
    26341 cgcggcccgg ccggcgatca gggagctgac gggcgcccct gcgggctggt gaccgccggc
    26401 ccgcgtcaca gcgggccgtc agaccactcg tgcgacggtg aggggcagcg ccgaccagat
    26461 caccttgccc cccgccgccg tgtgctccac gtcgcacacc ccgcccgcct cctgtgtgat
    26521 ctcgcgtacg aggaggaggc cgcggccgcc ggtccggccg tggtcggcct ccagggccgt
    26581 cgggcggtac gggtggctgt cctccacgga gacccgcacc cactcggcgc cgacggccac
    26641 ctcgacggcg agcatcgggg agagcaccgc cgcgtgccgg acggcattgg tcaccagctc
    26701 ggagacgatc agcagcagcc cctgcaccac atcgtccgag accg
//
