LOCUS       NZ_AP023440            20948 bp    DNA     linear   CON 26-MAY-2024
DEFINITION  Streptomyces aurantiacus strain JCM 4677 chromosome.
ACCESSION   NZ_AP023440
VERSION     NZ_AP023440.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces aurantiacus
  ORGANISM  Streptomyces aurantiacus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 9428393)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye
            Genome Coverage                   :: 62X
            Sequencing Technology :: Illumina HiSeq X Ten; PacBio Sequel II
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014701115.1-RS_2024_05_26
            Annotation Date                   :: 05/26/2024 05:58:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,211
            CDSs (total)                      :: 8,122
            Genes (coding)                    :: 7,928
            CDSs (with protein)               :: 7,928
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 194
            CDSs (without protein)            :: 194
            Pseudo Genes (ambiguous residues) :: 0 of 194
            Pseudo Genes (frameshifted)       :: 69 of 194
            Pseudo Genes (incomplete)         :: 161 of 194
            Pseudo Genes (internal stop)      :: 17 of 194
            Pseudo Genes (multiple problems)  :: 48 of 194
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:48:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 972882
            Orig. end                         :: 993830
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP023440.1.
            Genome sequencing and analysis were conducted under the Global
            Catalogue of Microorganisms (GCM) 10K type strain sequencing
            project (http://gctype.wdcm.org). The genomic data are also
            available at http://gctype.wdcm.org/sequencing/GCM10017557
            Annotated by DFAST v.1.2.7 (https://dfast.nig.ac.jp).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20948
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="5"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20948
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20948
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10948](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10948
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(10..25)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.11"
                     /tool="antismash"
     gene            557..2020
                     /locus_tag="IGS71_RS04120"
                     /old_locus_tag="GCM10017557_08460"
     CDS             557..2020
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1210: glycerol kinase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005320685.1"
                     /locus_tag="IGS71_RS04120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_08460"
                     /product="rhamnulokinase family protein"
                     /protein_id="WP_246596006.1"
                     /transl_table=11
                     /translation="MTNVTRRAAVKSYAAVDLGASSGRVMVGRVGPDSLDLTEAHRFPN
                     RPVRTPEGLRWDILALYAGVLDGLRAAGHVDSVGIDSWAVDYGLLDADGALLGNPAHYR
                     DPRTRGVAEQVWATVPAAELYAATGLQYAPFNTLYQLVAARSTAQLAHAKRLLLIPDLL
                     AYWLTGEAGTELTNASTTQLIDPRTGDWSYDIAARLGIDLELFAPLRRPGDPAGLLRPS
                     VLEETGLTGPVPVTTVGSHDTASAVAAVPAAGERFAYICTGTWSLAGLELTAPVLTEAS
                     RTANFTNELGLDGTVRYLRNIMGLWLLQECVREWGHPDLGELLSAAAEVPALRSVVDAG
                     DAAFLAPGRMPSRIADACRESGQPVPESRAEITRCILDSLALAHRRAVFEAQELAGHPV
                     DVVHIVGGGARNALLCRLTADACGLPVVAGPAEAAALGNVLVQARAHGQVGDRAEMRGL
                     LARTQPLTRYEPRGTTATWQAAEDRLTAR"
     gene            2190..2957
                     /locus_tag="IGS71_RS04125"
                     /old_locus_tag="GCM10017557_08470"
     CDS             2190..2957
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1261: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005484112.1"
                     /locus_tag="IGS71_RS04125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_08470"
                     /product="(Fe-S)-binding protein"
                     /protein_id="WP_190849409.1"
                     /transl_table=11
                     /translation="MRVALFLTCVNDTLYPDTGRAVVKLLTRLGVEVDFPMAQTCCGQA
                     HYNTGYRHEAEPLARHFSEVFGGYEAIVTPSGSCGAMVRELYPRMGERARAEGRGDGLA
                     ATLAPVVPKTYELTEFLVDVLGVTDVGAFYPHTVTYHPTCHGLRSLGLGDRPLRLLRSV
                     KGLELKELPGADECCGFGGTFALKNADVSAAMGADKVRNAESTGADVLCAADNSCLMHI
                     GGTMTRLRTGMRPVHIAEILASTEASTEEGPAA"
     gene            2986..4476
                     /locus_tag="IGS71_RS04130"
                     /old_locus_tag="GCM10017557_08480"
     CDS             2986..4476
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0019516 - lactate oxidation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006139325.1"
                     /locus_tag="IGS71_RS04130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_08480"
                     /product="LutB/LldF family L-lactate oxidation iron-sulfur
                     protein"
                     /protein_id="WP_246596007.1"
                     /transl_table=11
                     /translation="MSGGTYLGMPAFPKAAHEAVHNETLRGNLRHATHTIRAKREKAVA
                     EVSDWAELREAGKQIKDHTLRHLDRYLVQLEESVTAAGGTVHWAADADEANRIVTYLVK
                     ATGESEVVKVKSMATQEIGLNEALEAEGISAYETDLAELIVQLGKDRPSHILVPAIHRN
                     RGEIRDIFAREMSEWGRPAPEGLTDTPAELADAARLHLREKFLRAKVGVSGANFMVAET
                     GTMVVVESEGNGRMCLTLPETLISVVGIEKIVPTWRDLEVFLQTLPRSSTAERMNPYTS
                     TWTGTTDSESADGPRTFHLVLIDNGRTDTLADEVGRQALRCIRCSACLNVCPVYERAGG
                     HAYGSVYPGPIGAILSPQLRGTGSEIDASLPYASSLCGACYDVCPVAIDIPEVLVHLRE
                     RVVQGGAVTREGAKVVLKPAKGHAAERAAMRAARWAFSHPGVLRTGQRAASRTRRFHPR
                     TLPGPGKAWSETRSLPAVPAEPFRDWWQRTQGGKDASK"
     gene            4473..5120
                     /locus_tag="IGS71_RS04135"
                     /old_locus_tag="GCM10017557_08490"
     CDS             4473..5120
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057693.1"
                     /locus_tag="IGS71_RS04135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_08490"
                     /product="lactate utilization protein C"
                     /protein_id="WP_190849410.1"
                     /transl_table=11
                     /translation="MSSRDLILARVRRAIADVPRDDTPYEQAFERGYLREHGDRSVART
                     VDLLAENLADYRALVHRCTAGELAATIARLLAGRGAASVVVPAGLDPRWLAATEVTRVP
                     DRAADTPAELDRVDSVVTACAVAIAETGTIVLDGGPDQGRRRITLVPDHHICVVRVPGQ
                     VVSSVPQGLERVDPARPLTWISGPSATSDIELDRVEGVHGPRTLEVVLVSGE"
     gene            5143..6297
                     /locus_tag="IGS71_RS04140"
                     /old_locus_tag="GCM10017557_08500"
     CDS             5143..6297
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964372.1"
                     /locus_tag="IGS71_RS04140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_08500"
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="WP_190849411.1"
                     /transl_table=11
                     /translation="MIRFEQVTKRYPDGTTAVDGLSFEVAEGELVTLVGPSGCGKTTTM
                     MMVNRLIEPTSGRVLVDGEDIARVDPVRLRRRIGYVIQQVGLFPHRTILDNTATVPTLV
                     GWKRAKARARAAELLDLVGLDPKTFGPRYPDQLSGGQRQRVGVARALAADPPVLLMDEP
                     FGAVDPVTRDQLQDEFLRMQAAVRKTVLLVTHDIEEAVRLGDRIAVYGQGRIEQYDTPG
                     AVLGTPASPYVAEFVGADRGLKRLSVTAIEPDDLEQPPVARLDESAGRAAARLRAEGAR
                     WAVVLDAAGDLHGWVGADGLAAGGTVGELVHRMRSWVPVGAPLKQAFGVMLQHDAGWVA
                     VLDGAHFLGVLTPAKLHEALRRSVDADARGVARGQVEFDSVADA"
     gene            complement(6514..7458)
                     /locus_tag="IGS71_RS04145"
                     /old_locus_tag="GCM10017557_08510"
     CDS             complement(6514..7458)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010988803.1"
                     /locus_tag="IGS71_RS04145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_08510"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_055520539.1"
                     /transl_table=11
                     /translation="MRRRAALACLLLLLTGCVSGPSLESRGEVTAPPGDSENLTIGSAG
                     FTESDLLATLYGLLLEQAGYQTSTLTVANRELYEPALESGQIDVVAEYAATFADWLNAK
                     TNGADAAAVGSPDLDATMSALRKLAAPRGLTVLDPGRAVDQNAFAVTRAFAREHGLRTL
                     SDLGASGVRVRLAAGDECVRRPYCEPGLKKTYGIDITGVDPKGVGTTQAKRAVQNGQDQ
                     MVLTTTTDATLDDFGLVLLTDDRHLQNADYIVPVVNRSRAGDEKVTKALGPLNDVLTTA
                     DLADMNEQVDSWRRLPKDVARTYLKNKHLLKPP"
     gene            complement(7491..8156)
                     /locus_tag="IGS71_RS04150"
                     /old_locus_tag="GCM10017557_08520"
     CDS             complement(7491..8156)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018568493.1"
                     /locus_tag="IGS71_RS04150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_08520"
                     /product="ABC transporter permease"
                     /protein_id="WP_190849412.1"
                     /transl_table=11
                     /translation="MRTLTDGWDWLTDSAHWAGDDGIWHRLTQHLVLTVVCLVISCLIA
                     LPVALVLGHLGRGGALAVNISNVGRAVPTFAVLVLLLLTPIGDWGDGPTVVALVLFAVP
                     PLLTNAYVGMREVDRDVVRAARGMGMTGRQLLWRVEAPLALPMILGGVRIAAVQLVATA
                     TIAALAGGGGLGRIITAGFNLASTPQVVAGAVLVAVFALLVEGVFEVVERLAPGRGTR"
     gene            complement(8153..8833)
                     /locus_tag="IGS71_RS04155"
                     /old_locus_tag="GCM10017557_08530"
     CDS             complement(8153..8833)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057687.1"
                     /locus_tag="IGS71_RS04155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_08530"
                     /product="ABC transporter permease"
                     /protein_id="WP_190849413.1"
                     /transl_table=11
                     /translation="MTAPPDDCLARNEWICGAYLDTRRDILLDAVGQHLRLTALSVLIG
                     LAIALPLAVLARRWGWAAGPVLAVTTVLYTIPSLAMFSLLLPVYGLSAALVVAGLVLYS
                     LTLLVRNILAGLRAVPEETRQAARGMGYGPVRLLLTVELPLALPAAMAGLRIATVSAVS
                     LATVGAIVGFGGLGNLIYSGMNTYFKAQVLTASVLCVVIAVAADLLLLGLQWLITPWTR
                     AKRG"
     gene            8994..9932
                     /locus_tag="IGS71_RS04160"
                     /old_locus_tag="GCM10017557_08540"
     CDS             8994..9932
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014174386.1"
                     /locus_tag="IGS71_RS04160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_08540"
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="WP_190849414.1"
                     /transl_table=11
                     /translation="MTAHRTAARVVLAGTAPLLLAVGAAGPAAAHGAPTDPVSRVVACS
                     AEGGQRAQSAACRAAVASGVAAFDNLRLAGVAGRDRQVVPDGKLCSGGLAAYRGLDLAR
                     ADWPSTRLTAGADLTLTYRSTIPHTGTFKLFLTKDGYDPTKPLTWSDLPSRPFATATDP
                     ALVNGAYRISAKLPSDRTGRHLLYTIWQNTSTPDTYYSCSDVVFPGAKDNARSAGSTAS
                     AGSAARGRAESPAKSATPETTPTRASSKSPADVASTSAQPSRTPTGAPGEAVSSPASDK
                     DDRAPALPLIAGGAAGLLITAGAAYTLRRRR"
     misc_feature    complement(9989..10002)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.07"
                     /tool="antismash"
     gene            10001..10948
                     /locus_tag="IGS71_RS04165"
                     /old_locus_tag="GCM10017557_08550"
     CDS             10001..10948
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012705.4"
                     /locus_tag="IGS71_RS04165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_08550"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_190849415.1"
                     /sec_met_domain="phytoene_synt (E-value: 8.9e-34, bitscore:
                     115.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.3e-21,
                     bitscore: 76.0, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAFSGELYVRTWRRSLEAAEVRQDTLRDDYTKVARFMRRREPAGY
                     LAVRLLVPVGQQPHVLAGYAFASYTDDVCDRGTVQERTRRYDAWDERVRAALDSGSAGH
                     PLLRAFLHTAATRELPHRWVDSYLDGARIDLDFPGFATEADYQRYVEQLTWPFLMITSG
                     LAHQGGGSTEFAAACRLFADAAQRTDILTDLHEDLRGGRLYLPVSDLDRYDIAREDLEQ
                     GRDLPGVHALIAATAQTARATLREAGVLLDHCSEEHRRLMRFVLDLHHQRLQSVTSRGA
                     SVTRRPVRDRPVACLRLLTRRTPAHRDELAGTTR"
     gene            complement(11126..12091)
                     /locus_tag="IGS71_RS04170"
                     /old_locus_tag="GCM10017557_08560"
     CDS             complement(11126..12091)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1208: pirin
                     domain-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019068410.1"
                     /locus_tag="IGS71_RS04170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_08560"
                     /product="pirin family protein"
                     /protein_id="WP_190849416.1"
                     /transl_table=11
                     /translation="MSNLDRDAVPALCGGRGFVVAEPVRELLSPRRVKLGESSEVRRLL
                     PNLGRRMVGAWCFVDHYGPDDIAEEPGMQVPPHPHMGLQTVSWLHEGEVLHRDSTGSLQ
                     TIRPRELGLMTSGRAISHSEESPKSHARFLHGAQLWVALPDGDRHTEPRFEHHSELPVV
                     TAPGLTATVVLGGVDGAASPGTTYTPIVGADLALARGADLRLPLEPDFEYAVLSMSGEA
                     HVDGVPLLPGSMLYLGCGRTELPLRAESDAGLMLLGGEPFEEELVMWWNFIGRSQADIE
                     QARSDWMTGSRFGEVVGYGGGRLAAPALPPVALKPRGRVR"
     misc_feature    12213..12226
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.06"
                     /tool="antismash"
     misc_feature    12213..12227
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.44"
                     /tool="antismash"
     misc_feature    complement(12261..12275)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.92"
                     /tool="antismash"
     gene            12269..12616
                     /locus_tag="IGS71_RS04175"
                     /old_locus_tag="GCM10017557_08570"
     CDS             12269..12616
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009344144.1"
                     /locus_tag="IGS71_RS04175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_08570"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_055516971.1"
                     /transl_table=11
                     /translation="MDTTYYGHGTPAERWERARMFFDAKDYAASARVLGALVEEVPQET
                     GPRLLLARAYYHSAQLSRAEAELRVLVERDPVEHYARLMLGRTLQRQGRDDEAEPHMRL
                     ASALAGDFDTL"
     misc_feature    complement(12310..12324)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.98"
                     /tool="antismash"
     misc_feature    12311..12325
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.1"
                     /tool="antismash"
     gene            complement(12723..14156)
                     /locus_tag="IGS71_RS04180"
                     /old_locus_tag="GCM10017557_08580"
     CDS             complement(12723..14156)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994652.1"
                     /locus_tag="IGS71_RS04180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_08580"
                     /product="PepSY domain-containing protein"
                     /protein_id="WP_190849417.1"
                     /transl_table=11
                     /translation="MTTARTTETDESPQSVAPTPASRRGGWAPLRPLVLRLHFYAGVLV
                     APFLLVAATTGFLYAASFQAEKILYSHEMTVPVGDEKLPISEQVDAARAAHPEGTVSAV
                     RPSPEGDATTRVMLSGVPGIGGTHTLAVFVDPYTAKVRGALEQYGSTGALPLRTWIDEF
                     HANLRLGDNGRLYSELAASWLWVIAAGGLVLWFGRRRAQRKIRGTSGRRRTLGLHGSVG
                     AWVAVGFVFLSATGLTWSTYAGANIDELRTSLRQATPSVSAAAGGEHEGHGSGSDSAEG
                     GASGSAAGGVGLDKVLAAARAEGLGDPVEIVPPADASSAYVVSQVQRSFPTKQDTVAVD
                     PATGEVTDTVRFADYPVLAKLTRWGIDAHTGVLFGIVNQLVLMAVALSLILLILWGYRM
                     WWQRGRASAFGRPLPRGAWQQVPAHVLVPLMAGVAVLGYFVPLLGISLAAFVAVDVILG
                     EIAYRRGKRTYGPAKEAAK"
     misc_feature    complement(14255..14270)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.03"
                     /tool="antismash"
     gene            14367..15008
                     /locus_tag="IGS71_RS04185"
                     /old_locus_tag="GCM10017557_08590"
     CDS             14367..15008
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /GO_process="GO:0018206 - peptidyl-methionine modification
                     [Evidence IEA]"
                     /GO_process="GO:0031365 - N-terminal protein amino acid
                     modification [Evidence IEA]"
                     /GO_process="GO:0043686 - co-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006376460.1"
                     /locus_tag="IGS71_RS04185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_08590"
                     /product="peptide deformylase"
                     /protein_id="WP_190849418.1"
                     /transl_table=11
                     /translation="MASSSDLTPLRDLVEQLLSRTGPLPIVAAGDPVLRRAAEPFDGQL
                     DPSLLARFVAALRDTMHAAPGVGLAAPQVGVPLRLAVIEDPAPVPDEIREVRGRVPLPF
                     RVLVNPVYEPVGAARAAFFEGCLSVPGWQAVVARPAEVRLLAQDEHGSPVDEVFTGWPA
                     RIVQHETDHLDGMLYLDRAELRSLSSNEAMAERWTQPTPAEAAKGLGFPL"
     gene            complement(15054..16499)
                     /locus_tag="IGS71_RS04190"
                     /old_locus_tag="GCM10017557_08600"
     CDS             complement(15054..16499)
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006376456.1"
                     /locus_tag="IGS71_RS04190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_08600"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_190849419.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 8.3e-46, bitscore:
                     155.4, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTETDETHVYDVVVLGAGPVGENVADRARAAGLSAAIVESELV
                     GGECSYWACMPSKALLRPVIARADARRVPGLRQAVQGPLDAAAVLAHRDYFTSHWKDDG
                     QVQWLEGVGVDLYRGHGRLDGPRRVTVEGPGGERQVLTARHAVAVSTGTRAVLPDLPGL
                     AEVKPWTSREATGAQAVPGRLVVVGGGVVGVEMATAWQALGSQVTVLVRGKGLLPRMEP
                     FAGELVAEALTEAGADVRTGVSVESVTREGTTVVVTTSTGDRIEADEILFATGRAPRTE
                     DLGLETVGLTPGSWLEVDDSCRVTGSDWLYGVGDVNHRALLTHQGKYQARIAGAAIAAR
                     AAGVPLLETDPWGAHSATADHAAVPQVVFTDPEAAAVGLSLAEAEQAGHRVRAVDVDLA
                     TVAGAGLYADGYRGRARMIVDLDSETLRGVTFVGPGVGELIHSATIAVAGEVPVNRLWH
                     AVPSYPTVSEVWLRLLEAYRDGK"
     gene            16622..17020
                     /gene="trxA"
                     /locus_tag="IGS71_RS04195"
                     /old_locus_tag="GCM10017557_08610"
     CDS             16622..17020
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="trxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010988742.1"
                     /locus_tag="IGS71_RS04195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_08610"
                     /product="thioredoxin"
                     /protein_id="WP_190849420.1"
                     /transl_table=11
                     /translation="MSSTVELTKENFDQTVTDNEFVLIDFWASWCGPCRQFAPVYEKAA
                     EANADLVFAKVDTEAQPELAAAFNIQSIPTLMIIRDQVAIFAQPGALPETALVDVIGQA
                     RKLDMDEVRKSVAEQQTQQTQEAQETAE"
     misc_feature    complement(16656..16671)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 23.51"
                     /tool="antismash"
     gene            complement(17110..18144)
                     /locus_tag="IGS71_RS04200"
                     /old_locus_tag="GCM10017557_08620"
     CDS             complement(17110..18144)
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012999011.1"
                     /locus_tag="IGS71_RS04200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_08620"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_055516955.1"
                     /transl_table=11
                     /translation="MVQIPKPSAAPSPAQRSVPTSADVARLAGVSRATVSYVLNNTSAV
                     RISEPTRRRVHAAAEELGYVPHAAARSLRAGHSRMVLMPAPDVPVGPLYSQFFSELQWA
                     LSRLEYTVVQYGGLGVQGDDAARAWAELRPVAVLVPGGGLGPRGVSVLKRSGARAVVTL
                     GPERVEGAHALLMDHHGVGRQVGAHLLARGHRRVGVVVPEDPGLEIFSRPRLDGVRQAL
                     AGTDATVTELPLAYEEKAAADLAGRWRALGLDAVFAYNDEFAMLLMRALQDEGVGIPRE
                     TAVVGADDLMLGRLLRPRLSTVHIELPSGRELAELVDRAVREPAAPPETYQVLGAKVVH
                     RESS"
     misc_feature    complement(17623..17625)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(18133..18150)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            complement(18256..18918)
                     /locus_tag="IGS71_RS04205"
                     /old_locus_tag="GCM10017557_08630"
     CDS             complement(18256..18918)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020134980.1"
                     /locus_tag="IGS71_RS04205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_08630"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_190849422.1"
                     /transl_table=11
                     /translation="MSASLPPFPKHQEPTDEPVLLELGSAADEPCLRADAARNRARLLE
                     AATLLVEKHGAAGVTMEAVAVAASVGKGTVFRRFGDRTGLLMALLDHSAKQLQAAFLSG
                     PPPLGPGAPPVERLRAFGCAALRQAVDHLELQLAAQPEPARRYSNPPHRFLSGHVGLLL
                     RAAVPDADVTLLAQTLMGYLDPALIHHLTKECGMPLERLEAGWIDLVARVTRTELPQ"
     misc_feature    18999..19016
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.51"
                     /tool="antismash"
     gene            19036..19599
                     /locus_tag="IGS71_RS04210"
                     /old_locus_tag="GCM10017557_08640"
     CDS             19036..19599
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010043741.1"
                     /locus_tag="IGS71_RS04210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_08640"
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="WP_055516951.1"
                     /transl_table=11
                     /translation="MSVRILALVGSLRAGSHNRQLAEAAVKLAPEGAEIELFEGLADIP
                     FYNEDIDVEGDVPAAAARLREAVAGVDALLLFSPEYNGTIPAVLKNAIDWLSRPFGASS
                     ISAKPLAVVGTAYGQFGGVWAQDETRKAAGIAGAKVLEDVKLSIPGSVVRFAETHPSDD
                     AEVTAQLAEVIAQLHGQANSPVAA"
     gene            complement(19738..20619)
                     /locus_tag="IGS71_RS04215"
                     /old_locus_tag="GCM10017557_08650"
     CDS             complement(19738..20619)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006380302.1"
                     /locus_tag="IGS71_RS04215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017557_08650"
                     /product="LLM class F420-dependent oxidoreductase"
                     /protein_id="WP_190849423.1"
                     /transl_table=11
                     /translation="MRVGVHINRFNHPGGAVALGPELAAAGAAAEAAGVSWLSVMDHYF
                     QMEFNGGAEDAMLESYTTLGFLAAHTSTVRLGTLVTGVTYRRPGLLAKIATTLDVLSGG
                     RATLGIGAAWYDREHAGLGVPFPALAERFERLEETLRICLQMWDPQANGPFEGKHYRLA
                     ETLCVPAPVSTPRPEIMIGGSGEKKTLRLVARYGDACNLFASTPEEIGHKLDVLRGHCD
                     AVGREYADIRKTMLHSGNPGSQAELDAFTREMEDYAKLGIETVILGPRVDEPAEWIERT
                     AGPVVGRLAGLG"
ORIGIN
        1 tcggcggcgt cgacctggtc gtcaacaacg ccggcatctc catctccaag ccgctcctgg
       61 agaccacggc gaaggactgg gacctccagc acgacatcat ggcccgcggc tccttcctcg
      121 tctcgcgcga ggcggcccgg gtgatgatcg cgcaggaact cggcggggac gtcatctaca
      181 tcgcgtccaa gaacgccgtg ttcgccggtc cgaacaacat cgcctactcg gccacgaagg
      241 ccgaccaggc ccatcaggtg cggttgctcg ccgccgagct gggcgagcac ggcatccggg
      301 tcaacggcat caaccccgac ggcgtcgtcc gcggttcggg gatcttcgcg ggcggctggg
      361 gcgcccagcg cgcggccacc tacggcatcg aggaggagaa gctcggcgag ttctacgccc
      421 agcggaccat cctcaagcgc gaggtcctcc ccgagcacgt cgcgaacgcc gtgttcgccc
      481 tgacgggcgg cgacctcacc cacaccaccg gactgcacgt cccggtcgac gccggtgtcg
      541 ccgccgcgtt cctccgatga cgaacgtgac ccgccgggcg gctgtgaagt cgtacgccgc
      601 ggtcgacctc ggcgcgtcca gcgggcgcgt catggtcggc cgcgtgggcc ccgactcgct
      661 ggacctgacg gaggcgcacc gcttcccgaa ccggccggtg cgcacccccg aaggactgcg
      721 ctgggacatc ctcgcgctgt acgcgggggt cctcgacggg ctgcgcgcgg ccgggcacgt
      781 cgactcggtc ggcatcgaca gctgggccgt ggactacggc ctgctcgacg ccgacggggc
      841 gctgctcggc aacccggcgc actaccggga cccccgcacg cggggcgtcg cggagcaggt
      901 gtgggccacc gtgcccgccg ccgagctgta cgcggccacc ggactccagt acgccccctt
      961 caacacgctg taccagctgg tggcggcccg ctccacggcc caactggctc acgcgaagcg
     1021 gctgctcctc atccccgacc tgctggcgta ctggctcacg ggcgaggcgg gcacggagct
     1081 caccaacgcc tccacgaccc agctgatcga cccacgcacc ggcgactggt cgtacgacat
     1141 agcggcgcgt ctcggcatcg acctggagct gttcgcgccg ctgcggcggc ccggcgaccc
     1201 ggccggactg ctgcggccga gtgtcctgga ggagaccggg ctgaccggtc cggtaccggt
     1261 gacgacggtc ggctcccacg acaccgcctc ggcggtggcc gccgtcccgg ccgcgggcga
     1321 gcggttcgcg tacatctgca ccggcacctg gtccctcgcg ggcctggagc tgacggcacc
     1381 cgtcctcacc gaggcgagcc gcacggcgaa cttcaccaac gaactgggcc tggacggcac
     1441 ggtccgctac ctgcggaaca tcatggggct ctggctgctc caggagtgcg tacgggaatg
     1501 ggggcacccc gacctgggag agctgctgtc ggccgccgcc gaggtgccgg cgctgcggtc
     1561 cgtggtggac gcgggcgacg cggcgttcct ggcccccggc cggatgccgt cccggatcgc
     1621 cgacgcctgc cgggagtcgg ggcagcccgt gcccgagtcc cgggccgaga tcacccgctg
     1681 catcctcgac tcgctggcgc tcgcccaccg ccgggcggtc ttcgaggcac aggagctggc
     1741 cggccacccg gtcgacgtcg tgcacatcgt cggcgggggc gcccgcaacg ccctgctgtg
     1801 ccggctcacg gccgacgcct gcgggctgcc cgtggtggcg ggcccggcgg aggcggcggc
     1861 actgggcaac gtcctggtgc aggcgcgggc ccacggccag gtcggcgacc gcgcggagat
     1921 gcgcggactc ctggcccgta cccagccact gacccgctac gagccccggg gcaccacggc
     1981 gacctggcag gcagccgagg accgcctgac cgcccgatga caaaagttcc cgcccccggc
     2041 accggcgcgc cccgaaaggg gcgcggggaa ctgcgcgacc agccacaccc ggcccgcagc
     2101 caacactcaa cagtcaccgc cgctcattcc ggccaagccc agcgccgcgt aacgtgcagt
     2161 cgtccgacca ccaaccccaa ggagccgcga tgcgtgtcgc cctgttcctg acctgtgtca
     2221 acgacacgct ctatccggac acgggccggg ccgtggtgaa gctgctgacc aggctgggcg
     2281 tcgaggtcga cttcccgatg gcgcagacct gttgcgggca ggcgcactac aacaccgggt
     2341 accggcacga ggccgagcct ctggcccggc acttctccga ggtgttcggt gggtacgagg
     2401 cgatcgtgac cccctccggg tcgtgcggcg cgatggtgcg cgagctgtat ccgcggatgg
     2461 gcgagcgggc gcgcgccgag ggacgcgggg acggcctcgc cgccaccctc gcaccggtcg
     2521 tgccgaagac gtacgagctc accgagttcc tggtggacgt gctgggcgtg acggacgtgg
     2581 gcgcgttcta cccgcacacc gtcacctacc accccacctg tcacggactg cgcagtctcg
     2641 gtctgggcga ccggccgctg cggctgctca ggtccgtcaa gggacttgag ctgaaggagc
     2701 tgccgggcgc cgacgagtgc tgcggcttcg gcggcacctt cgccctcaag aacgccgacg
     2761 tgtcggcggc gatgggcgcc gacaaggtcc gcaacgccga gtcgacgggc gccgacgtgc
     2821 tgtgtgccgc cgacaactcc tgtctgatgc acatcggcgg cacgatgacc cggctcagga
     2881 cgggcatgcg cccggtgcac atcgcggaga tcctggcgag tacggaagcg agtacggaag
     2941 aggggccggc ggcatgaaca aggacagcgg acaggagccg ggcgcatgag cggtggcacc
     3001 tatctcggga tgccggcctt cccgaaggcc gcgcacgagg ccgtccacaa cgaaaccctg
     3061 cgcggcaacc tgcggcacgc gacgcacacc atccgcgcca agcgggagaa ggcggtcgcg
     3121 gaggtctccg actgggccga gctgcgcgag gccggcaagc agatcaagga ccacacgctc
     3181 cgccatctcg accggtatct ggtgcagttg gaggagtcgg tcacggcggc gggcggcacc
     3241 gtgcactggg ccgccgacgc ggacgaggcc aaccgcatcg tcacgtacct cgtcaaggcg
     3301 accggcgaga gcgaggtcgt caaggtcaag tcgatggcca cgcaggagat cggcctcaac
     3361 gaagcgctgg aggccgaggg catcagcgcc tacgagaccg acctcgccga actgatcgtg
     3421 cagctgggca aggaccggcc ctcgcacatc ctggtcccgg ccatccaccg caaccgcggc
     3481 gagatccgcg acatcttcgc cagggagatg agcgagtggg ggcggccggc tccggaggga
     3541 ctgaccgaca cgcccgccga gctggccgac gcggcgcgcc tgcatctgcg cgagaagttc
     3601 ctgcgcgcca aggtcggcgt gtcgggcgcc aacttcatgg tcgccgagac cggcaccatg
     3661 gtcgtggtcg agtccgaggg caacggccgg atgtgcctca ccctccccga gacgctcatc
     3721 tcggtcgtcg gcatcgagaa gatcgtgccg acctggcggg acctggaggt cttcctgcaa
     3781 accctccccc gctcctcgac ggccgagcgc atgaacccgt acacgtcgac gtggacgggc
     3841 acgacggact ccgagagcgc cgacggcccc cgcaccttcc acctggtcct catcgacaac
     3901 gggcgcaccg acacgctcgc cgacgaggtg ggccgccagg ccctgcgctg catccgctgc
     3961 tcggcgtgtc tcaacgtctg cccggtgtac gagcgggcgg gcggccacgc gtacggctcg
     4021 gtctacccgg gcccgatcgg cgcgatcctc agcccccagc tccggggcac cggcagcgag
     4081 atcgacgcct ctctcccgta cgcgtcgtcg ctgtgcggtg cctgctacga cgtgtgcccg
     4141 gtggcgatcg acatcccgga ggtgctggtg cacctgcggg aacgggtcgt gcagggcggt
     4201 gccgtgaccc gcgagggcgc caaggtcgtg ctcaagcccg cgaaggggca cgccgccgag
     4261 cgtgcggcga tgcgcgccgc gcggtgggcg ttcagtcatc cgggcgtgct gcgcacgggc
     4321 cagcgggccg cgtcccgcac gcgccgcttc catccacgga cgctgcccgg tcccggcaag
     4381 gcgtggagcg aaacgcggtc gctgccggcg gttcccgcgg agccgttccg cgactggtgg
     4441 cagcggacac agggcggaaa ggacgcgtcg aagtgagcag cagggatctg atcctggccc
     4501 gggtgcggcg tgcgatcgcc gacgtcccgc gggacgacac gccgtacgag caggccttcg
     4561 agcgcgggta tctgcgcgag cacggggacc ggagtgtcgc gcggacggtg gatctgctgg
     4621 cggagaacct ggcggactac cgggccctcg tgcaccgctg tacggccggt gagctggccg
     4681 cgacgatcgc ccggctgctg gccgggcggg gtgcggcgtc ggtcgtcgtg ccggcgggcc
     4741 tcgacccgcg ctggctggcg gccacggagg tcacgcgggt gcccgaccgt gccgcggaca
     4801 ccccggccga actggaccgc gtcgacagcg tggtcacggc gtgcgccgtc gccatcgccg
     4861 agaccggcac catcgtcctc gacggcggcc cggaccaggg ccgccgccgg atcacgctgg
     4921 tcccggacca ccacatctgc gtcgtacgcg tccccggcca ggtcgtgtcc tccgtgcccc
     4981 agggcctgga gcgcgtcgac ccggcccgcc cgctgacctg gatctcgggt ccgtcggcca
     5041 ccagcgacat cgaactcgac cgggtcgagg gggtgcacgg tccgcgcacc cttgaggtgg
     5101 tgctggtgag cggagagtga caggcgcggt tagcgtgagg tcatgatccg gttcgagcag
     5161 gtcaccaagc ggtatccgga cggtacgacc gcggtggacg ggctctcctt cgaggtggcc
     5221 gagggtgaac tcgtcacgct cgtgggcccg tccggctgtg gcaagacgac gaccatgatg
     5281 atggtcaacc gtctcatcga gccgacctcc ggccgggtcc tcgtcgacgg cgaggacatc
     5341 gcacgggtcg acccggtacg gctgcggcgg cggatcggtt acgtcatcca gcaggtgggc
     5401 ctcttcccgc accgcacgat cctcgacaac acggcgaccg tgcccaccct cgtcggctgg
     5461 aagagggcga aggcacgggc gcgggccgcc gagttgctcg acctggtggg cctggacccg
     5521 aagacgttcg gcccgcgcta tccggaccag ctgtcgggcg gccagcgcca gcgggtcggc
     5581 gtggcgcgcg cgctggccgc cgacccgccg gtgctgctga tggacgagcc gttcggggcg
     5641 gtcgacccgg tgacgcggga ccagttgcag gacgagttcc tgcggatgca ggcggccgtg
     5701 cgcaagacgg tgctgctggt cacgcacgac atcgaggagg ccgtacggct cggcgaccgc
     5761 atcgccgtgt acgggcaggg ccgtatcgag cagtacgaca cgcccggggc ggtgctgggt
     5821 accccggcgt ccccgtacgt cgccgagttc gtgggcgccg accggggcct gaagcggctg
     5881 tcggtcaccg cgatcgagcc cgacgacctg gaacagccgc cggtcgcccg tctcgacgag
     5941 agcgccggcc gggccgcggc ccggctgcgc gcggagggtg cgcgctgggc ggtcgtcctg
     6001 gacgcggcgg gcgatctgca cggctgggtg ggtgccgacg ggctcgccgc gggcggcacg
     6061 gtcggcgaac tcgtccaccg gatgaggtcc tgggtcccgg tgggcgcccc gctgaagcag
     6121 gccttcggcg tgatgctcca gcacgacgcc gggtgggtgg cggtgctcga cggggcgcac
     6181 ttcctcggcg tactgacccc ggcgaagctg cacgaggcgc tgcggcggtc ggtggacgcg
     6241 gatgcgcgcg gggtggcgcg ggggcaggtg gagttcgact ctgtcgccga cgcgtgagcg
     6301 ctccgcgtga acgctccgct ggggcggggg atttacctgc gggccggtgg gggtttggcg
     6361 cgccgttccc cgcgcccctg accgggcccg gcacggtgat tcgcccgcgg gccggtgggg
     6421 gtttggcgcg ccgttccccg cgcccctgac ggggcgccgc accgtcttgg tccgcgggtt
     6481 cgtgggggct tggcgtgccg ttcctcgcgc cccttacggg ggcttcagta ggtgtttgtt
     6541 cttcaggtag gtgcgggcca cgtctttcgg taggcggcgc cagctgtcca cctgttcgtt
     6601 catgtcggcc aggtcggcgg tcgtcagtac gtcgttgagg gggccgagtg ccttggtgac
     6661 cttttcgtcg cccgctcggg agcggttgac gaccggcacg atgtagtcgg cgttctgcag
     6721 gtgtctgtcg tcggtgagca ggacgagccc gaagtcgtcg agcgtcgcgt ccgtcgtggt
     6781 ggtcagcacc atctggtcct ggccgttctg cacggcccgt ttcgcctggg tggtgccgac
     6841 gcccttgggg tccacgccgg tgatgtcgat gccgtacgtc ttcttcaacc ccggttcgca
     6901 gtacggccgt cgcacgcact cgtcgcccgc cgcgagccgt acccggacac cggacgcgcc
     6961 caggtcgctg agtgtcctca ggccgtgttc gcgtgcgaag gcccgggtca cggcgaaggc
     7021 gttctggtcg accgccctgc cggggtcgag gacggtgagt ccccggggcg cggccagctt
     7081 ccgcagcgcg ctcatcgtgg cgtccaggtc cggcgagccg acggcggccg cgtccgcccc
     7141 gttggtcttg gcgttcagcc agtccgcgaa ggtggccgcg tactcggcga cgacgtcgat
     7201 ctgccccgac tccagggccg gttcgtacag ttcgcggttg gcgacggtca acgtggacgt
     7261 ctggtagccc gcctgttcca gcagcagccc gtacagggtg gccagcaggt cgctctcggt
     7321 gaagccggcc gagccgatgg tgaggttctc gctgtcgccg ggcggtgcgg tgacctctcc
     7381 ccggctctcc agggagggac cggatacgca accggtcagc agaagcagga ggcaggcgag
     7441 ggccgcgcga cgcctcatcg ggtgcgcggt cctcgtccga tacgccgtcc tcatcgggtg
     7501 ccccggccgg gcgccagtcg ctcgaccacc tcgaaaacgc cttcgacgag gagcgcgaag
     7561 acggccacga ggacggcgcc ggcgacgacc tgcggcgtac tcgccaggtt gaacccggcg
     7621 gtgatgatcc gtccgagtcc gccgccgccc gccagcgcgg cgatcgtggc ggtggccacg
     7681 agctgtacgg ccgcgatgcg cactccgccc aggatcatcg gcagcgcgag cggcgcctcg
     7741 acccgccaca gcagctgccg accggtcatc cccatgcccc gggccgcccg caccacgtca
     7801 cggtcgacct cgcgcattcc gacgtacgcg ttggtgagca gcggcggtac ggcgaacagg
     7861 acgagcgcga cgaccgtggg gccgtcgccc cagtcgccga tcggggtgag cagcagcagg
     7921 acgagcaccg cgaaggtggg gacggcccgg ccgacgttcg agatgttgac ggcgagcgcg
     7981 ccgcccctgc cgaggtggcc gaggacgagg gcgaccggca gcgcgatcag acagctgatc
     8041 accaggcaga ccacggtcag cacgaggtgc tgggtgagcc ggtgccagat gccgtcgtcg
     8101 cccgcccagt gcgcggagtc ggtgagccag tcccagccgt cggtgagtgt cctcatccgc
     8161 gcttcgctct cgtccagggg gtgatcagcc actggagccc gagcagcagc agatcggcgg
     8221 cgaccgcgat gaccacgcac agcacggacg cggtgaggac ctgggccttg aagtaggtgt
     8281 tcattcccga gtagatgagg ttgccgagcc ctccgaagcc gacgatcgcg ccgaccgtgg
     8341 cgagcgacac cgccgagacg gtggcgatcc tgagtccggc catggcggcg ggcagggcga
     8401 gcggcagctc gacggtgagc agcaggcgca cgggcccgta tcccatgccg cgggccgcct
     8461 gccgggtctc ctcggggacg gcccggagcc cggccaggat gttccgtacg agcagggtca
     8521 gcgagtagag gacgaggccg gcgacgacca gggccgccga cagtccgtac accggcagga
     8581 gcagcgagaa catggcgagc gaggggatcg tgtagaggac cgtcgtgacg gcgagcaccg
     8641 gtcccgccgc ccagccccag cggcgcgcga gcacggcgag gggcagggcg atcgccaggc
     8701 cgatgaggac ggagagagcg gtcagccgaa ggtgctggcc gaccgcgtcg aggaggatgt
     8761 cgcggcgggt gtccaggtat gcgccgcaga tccactcgtt gcgcgcgagg cagtcgtccg
     8821 ggggcgcggt cacgggtcca gtccatcggg gcgggcggcg gactgcgcgt ggtgatggcc
     8881 cgtacggggg gggacggggg agttgaacgc ccctcgcgcc gctcccgtac ttgaggggca
     8941 gcgggctctc ggctgtcgag tacctgcctg ccgtgcccgg aggagtcccg tccatgaccg
     9001 cacaccgcac cgccgcccgc gtcgtccttg ccgggacggc cccgctcctg ctcgcggtgg
     9061 gggccgccgg gcccgccgcc gcgcacgggg cgccgacgga tccggtcagc cgggtggtgg
     9121 cctgctccgc cgagggcggg cagcgggcgc agtcggcggc ctgccgggcc gctgtcgcct
     9181 ccggcgtggc cgccttcgac aacctgcggc tggcgggcgt cgcaggccgg gaccggcagg
     9241 tcgtgcccga cggcaagctg tgcagcggcg gcctcgccgc ctaccggggg ctcgacctgg
     9301 cccgcgccga ctggccctcg acccggctga ccgccggggc ggacctgacg ctcacgtacc
     9361 ggtcgacgat cccgcacacg ggcacgttca agctgttcct gaccaaggac ggctacgacc
     9421 cgacgaagcc gctcacgtgg tccgacctgc cgtcccggcc cttcgcgacg gccaccgacc
     9481 cggccctggt gaacggtgcc taccggatca gcgccaagct gccgtccgac cgcaccggcc
     9541 gccacctgct gtacacgatc tggcagaaca cgagcacgcc ggacacctac tactcgtgct
     9601 cggacgtggt cttccccggc gcgaaggaca acgcccggtc cgccggttcc acagcgtccg
     9661 ccgggtccgc ggcgcgaggg cgcgcggagt caccggcgaa gtccgccacg ccggagacca
     9721 cccccacccg ggcctcctcg aagtccccgg ccgacgtggc gagtacgtcg gcgcagccgt
     9781 cgcggacgcc gaccggcgcg cccggcgagg cggtctcctc ccccgcctcc gacaaggacg
     9841 accgcgcgcc ggccctgccc ctgatcgcgg gcggcgcggc gggtctgctg atcacggcgg
     9901 gcgccgcgta caccttgcgc aggcggcgct gacgcgccgg gcctgccgac agccggagat
     9961 cacactcctg atagcctgcg cgtcgcttcg gtagtgaaaa atggcattct caggggagct
    10021 gtacgtgcgg acctggcgga ggagcctgga agcggccgag gtgcgccagg acaccctgcg
    10081 cgacgactac acgaaggtcg cgcggttcat gcggcggcgg gagccggccg gctacctggc
    10141 ggtacgcctg ctggtgcccg tgggccagca gccccatgtg ctcgccggat acgccttcgc
    10201 gtcgtacacc gacgacgtct gcgaccgggg cacggtccag gagcgcaccc gacgctacga
    10261 cgcgtgggac gagcgggtgc gcgcggcgct ggactcggga agcgccgggc atccgctgct
    10321 gcgcgcgttc ctgcacacgg cggccacccg tgaactgccg caccggtggg tcgactcgta
    10381 cctggacggc gcgcggatcg acctcgactt ccccggcttc gccaccgagg ccgactacca
    10441 gcggtacgtg gaacagctca cctggccgtt cctgatgatc acctcgggcc ttgcccatca
    10501 gggcggcggc agcaccgagt tcgccgccgc ctgccgtctg ttcgccgacg cggcccaacg
    10561 gacggacatc ctgaccgacc tgcacgagga cctgcgcggc gggcgcctgt acctgcccgt
    10621 cagcgatctc gaccggtacg acatcgcgcg cgaggacctc gaacagggcc gcgacctgcc
    10681 cggcgtacac gcgctgatcg cggccaccgc gcagaccgcg cgcgccacgc tccgggaggc
    10741 cggcgtactc ctcgaccact gctccgagga acaccggcgc ctgatgcgtt tcgtactgga
    10801 cctgcaccat cagcgcctgc agtcggtgac gtcccgcggc gcctcggtga cccgccgccc
    10861 ggtacgcgac cgcccggtgg cctgcctgcg cctgctgacc cgccgcacac cggcccaccg
    10921 ggacgaactc gccggaacga cccggtaacg ctcccaccgg ccaacacatc tgccgagcag
    10981 cgccgccacc gaccgccgct cttttcaggg gcaggggcgc ggggaactgc gcatctttta
    11041 ggggcgcggg gaactgcgcg acaagccgca ctcgatccgc agcagccgga ccgggccggt
    11101 ggcaccccag gccctccacc agagctcagc gcacgcgccc ccgcggtttc agcgcaaccg
    11161 gcggaagcgc gggagcagcc agccgccccc cgccgtaccc caccacctca ccgaaccgcg
    11221 accccgtcat ccagtccgac cgcgcctgct cgatgtccgc ctgggaccgc ccgatgaagt
    11281 tccaccacat gaccagctcc tcctcgaacg gctcgccgcc gagaagcatg agaccggcgt
    11341 ccgactccgc ccgcaggggc agctcggtgc gaccgcagcc gaggtagagc atggagccgg
    11401 gcagcagcgg cacaccgtcc acgtgcgcct cgccggacat ggacagcacg gcgtactcga
    11461 agtccggctc cagcggcagg cgcaggtccg ccccgcgggc gagcgccagg tcggcgccga
    11521 cgatcggcgt gtacgtcgtc cccggcgagg ccgcgccgtc gacgccgccc aggacgaccg
    11581 tggcggtcag accgggagcc gtcaccacgg gcagctcgct gtggtgctcg aaacgcggct
    11641 cggtgtggcg gtcgccgtcg ggcagagcga cccacagctg cgcgccgtgc aggaagcggg
    11701 cgtgcgactt ggggctctcc tccgagtgac tgatggcccg gccggaggtc atgaggccca
    11761 gctcacgagg gcggatcgtc tgcaggctgc ccgtggagtc gcggtgcagc acctcgccct
    11821 cgtgcagcca gctgacggtc tgcaggccca tgtgcggatg cggcgggacc tgcatgccgg
    11881 gctcttcggc gatgtcgtcg ggaccgtagt gatcgacgaa gcaccaggcg cccaccatgc
    11941 gccggcccag gttgggcagc agacgccgga cttcgctgga ctcgccgagc ttgacccggc
    12001 ggggactgag gagttcacgc accggctccg ccaccacgaa accccggccg ccgcacagcg
    12061 cgggaacagc atcgcgatca agattgctca tggcgcacaa cctagcccgt ggaggacggt
    12121 ccgtcaggcc ccgtcccccg cccgtccccg tccggtcccc accccgtccc cgtccggtcc
    12181 ccccgccggt cggccaccgc cataggtcgt ggaatattca acaaactaag gtggttctgc
    12241 ccgtcgaagg aggtcggacg tggacacgat ggacacgacg tactacggcc acgggacgcc
    12301 cgcggagcgc tgggagcgcg cccggatgtt cttcgacgcc aaggactacg ccgcctcggc
    12361 gcgcgtactc ggcgccctgg tcgaggaggt gccgcaggag acgggccccc gtctgctgct
    12421 ggcccgcgcg tactaccact cggcccagct gagccgggcg gaggccgaac tgcgcgtcct
    12481 cgtcgagcgg gaccccgtgg agcactacgc ccgcctcatg ctcggccgca cgctccagcg
    12541 ccagggccgg gacgacgagg ccgagccgca tatgcgactg gcctcggccc tcgcgggaga
    12601 tttcgacacc ctgtgagcag gacagaacag gacagggcag gcaaggcagc gaggagcccg
    12661 gcggcgtgac gaccgccggg ctcctcgctc cggccgctgg gctccgggcc tgctcgaacc
    12721 tgctacttcg ccgcctcctt ggcgggcccg tacgtgcgtt tgccccgccg gtaggcgatc
    12781 tcgcccagga tcacgtccac cgcgacgaag gccgccagtg agatgccgag gagcggcacg
    12841 aagtagccga ggacggcgac gcccgccatc agtgggacga ggacgtgcgc gggcacctgc
    12901 tgccaggcgc cgcgcgggag gggacggccg aaggcggagg cgcggccccg ctgccaccac
    12961 atgcggtagc cccacaggat cagcaggatc aggctgagcg cgacggccat cagtacgagc
    13021 tggttgacga tgccgaagag gacaccggtg tgcgcgtcga tgccccagcg ggtgagtttc
    13081 gccagcaccg ggtagtcggc gaagcgcacc gtgtcggtga cctcgccggt cgccgggtcg
    13141 accgcgacgg tgtcctgctt ggtggggaag ctgcgctgga cctggctgac gacgtaggcc
    13201 gacgaggcgt cggcgggcgg gacgatctcc accgggtcgc ccagtccctc cgcccgcgcg
    13261 gcggccagca ccttgtcgag gccgactccc ccggcggcac tccccgaggc accgccctcg
    13321 gccgagtcgg agccggagcc gtgtccttcg tgctcgccgc ccgcggcggc cgagaccgac
    13381 ggggtcgcct ggcgcagcga ggtgcgcagt tcgtcgatgt tcgccccggc gtacgtcgac
    13441 caggtcaggc ccgtcgccga gaggaagacg aagccgaccg cgacccaggc gccgaccgag
    13501 ccgtgcaggc cgagggtgcg ccggcggccg ctggtgccgc gtatcttgcg ctgcgcacga
    13561 cggcggccga accagagcac caggccgccg gccgcgatca cccacagcca gctggcggcg
    13621 agttcgctgt agagccggcc gttgtcgccg agcctgaggt tcgcgtggaa ctcgtcgatc
    13681 caggtgcgca gcggcaacgc gccggtggat ccgtactgtt cgagcgcgcc gcgcaccttg
    13741 gcggtgtacg ggtccacgaa caccgcgagg gtgtgggtcc cgccgatgcc ggggacgccg
    13801 gacagcatca ccctggtggt ggcgtcgccc tcgggtgagg ggcgtacggc ggagaccgtt
    13861 ccctcggggt gggcggcgcg ggcggcgtcg acctgttcgg agatcggcag cttctcgtcg
    13921 ccgacgggca cggtcatctc gtgcgagtag aggatcttct cggcctggaa cgacgccgcg
    13981 tacaggaatc cggtggtggc ggcgacgagc aggaacgggg cgacgagcac tccggcgtag
    14041 aagtgcagcc gcagcaccag cgggcgaagc ggcgcccaac cgccgcgtct ggatgcggga
    14101 gtgggagcga cggactgcgg ggactcgtcc gtctcggtcg tgcgagcggt ggtcatcggc
    14161 tggcttctcc ggtcgggcag gggacgacgg ggccgtactc ggccgttgcg gtgcagtagt
    14221 cggtgggcgg ggccgtcgag ttcccggagg tttgtgtggc gtgtgtcaca ggtctgccga
    14281 gggggccggt gccgtacccg gaaagccctc gcccctgccc gggagccgcc tcgcgccccg
    14341 ggcgcccggc ttggcatgct ggcgcgatgg catcatccag tgacctcacg cccctgcgcg
    14401 acctagtgga gcaactgctc tcccgtacgg gcccgttgcc gatcgtcgcc gccggtgacc
    14461 cggtgctgcg ccgtgcggcc gagccgttcg acggccagtt ggacccctcg ctcctggccc
    14521 gcttcgtcgc ggccctgcgc gacacgatgc acgccgcgcc gggagtcggc cttgccgcgc
    14581 cccaggtggg cgttcccctg cgcctcgcgg tgatcgagga cccggcgccg gtcccggacg
    14641 agatccgcga ggtacgcggc cgggtgccgc tgcccttccg cgtcctggtc aacccggtgt
    14701 acgagcccgt gggtgccgcc cgtgcggcgt tcttcgaggg ctgcctgagt gtgccgggct
    14761 ggcaggcggt ggtggcgagg ccggccgagg tgcggctgct ggcccaggac gagcacggga
    14821 gcccggtgga cgaggtgttc acgggctggc ccgcgcggat cgtccagcac gagacggacc
    14881 acctggacgg catgctctat ctcgaccgcg cggaactgcg ctccctgtcc tccaacgagg
    14941 cgatggcgga gcggtggacc cagccgactc cggcggaggc ggcgaagggg ctgggcttcc
    15001 ccctctgaac cgcgcccccg ccgccgtcgg tgggtcacct cggagtcggt ccgctacttc
    15061 ccgtcgcggt acgcctccag cagcctcagc cacacctcgc tgaccgtcgg gtaggacggg
    15121 accgcgtgcc acaggcggtt caccgggacc tcgccggcga ccgcgatcgt ggcggagtgg
    15181 atcagctcgc cgacgccggg gccgacgaac gtgacgccgc gcagggtctc gctgtccagg
    15241 tcgacgatca tccgggcccg gccgcggtag ccgtcggcgt acaggccggc gccggcgacc
    15301 gtggcgaggt cgacgtcgac cgccctgacc cggtggccgg cctgctcggc ctcggcgagg
    15361 gacaggccca cggcggcggc ctccgggtcg gtgaagacga cctggggaac ggcggcgtgg
    15421 tcggcggtgg ccgagtgcgc gccccagggg tcggtctcca gaagcgggac accggccgcc
    15481 cgggcggcga tggcggcgcc cgcgatccgg gcctggtact tgccctggtg ggtgagcagg
    15541 gcacggtggt tgacgtcgcc gaccccgtac agccagtcgc tgcccgtgac ccggcagctg
    15601 tcgtcgacct ccagccagga accgggcgtg aggccgaccg tttcgagccc gaggtcctcg
    15661 gtgcgcgggg cgcgtccggt ggcgaagagg atctcgtcgg cctcgatgcg gtcacccgtg
    15721 gaggtggtga cgacgaccgt cgtaccctcc cgtgtcaccg actcgaccga gacacccgta
    15781 cgcacgtccg cgcccgcctc cgtgagggcc tcggcgacca gttcaccggc gaagggctcc
    15841 atacggggca gcaggccctt gccgcggacg aggaccgtga cctgggagcc gagtgcttgc
    15901 caggccgtgg ccatctccac gcccacgacc ccgccgccga ccaccacgag gcggcccggg
    15961 acggcctgcg cgccggtggc ctcgcggctg gtccagggct tgacctcggc gagtcccggc
    16021 aggtcgggca gcacggcgcg ggtgccggtg ctgacggcca cggcgtgccg ggcggtcagt
    16081 acctgccgct ccccgccggg gccctcgacc gtgacccggc gcggtccgtc gagccggccg
    16141 tgcccccggt agaggtcgac cccgacgcct tcgagccact ggacctggcc gtcgtccttc
    16201 cagtgcgagg tgaagtagtc gcggtgggcg aggaccgcgg ccgcgtcgag gggaccctgc
    16261 acggcctggc gcaggccggg caccctgcgg gcgtccgcgc gggcgatgac cgggcgcagc
    16321 agtgccttgc tgggcatgca ggcccagtac gagcactctc cgccgaccag ctcgctctcc
    16381 acgatcgcgg cggagaggcc ggccgcgcgg gcgcggtcgg cgacgttctc ccccacgggc
    16441 ccggccccca gcaccacgac gtcgtacaca tgggtctcat cggtttccgt atccgtcatg
    16501 gggccagtct ggtcgttggt gtgggtcgtg gccacacggg tagtgcacgg aatacggcgc
    16561 cggtctgcgc cgttgtgcac aaacggccac cgcaccgacc cagggaagag ggatcaacac
    16621 catgagcagc accgtggagc tcaccaagga gaacttcgac cagacggtca cggacaacga
    16681 gttcgtcctg atcgatttct gggcatcctg gtgcggcccg tgccggcagt tcgccccggt
    16741 ctacgagaag gcggcggagg ccaacgccga cctggtgttc gccaaggtgg acacggaggc
    16801 acagccggag ctggccgcgg ccttcaacat ccagtcgatc ccgacgctga tgatcatccg
    16861 tgaccaggtg gcgatcttcg cccagccggg ggcgctgccc gagaccgcgc tggtggacgt
    16921 catcggccag gcccggaagc tggacatgga cgaggtccgc aagtccgtcg cagagcagca
    16981 gacgcagcag acgcaggagg cgcaggagac ggccgagtag gttcggagcc ggtctccggg
    17041 cctgttcagg tccgtacggc acgtgtcata cggcacatgt cccggtcgta cggcacgtgt
    17101 cccgggcgtt cagctcgact cgcggtgcac gaccttcgcg cccagtacct ggtacgtctc
    17161 gggcggtgcg gcgggctcgc gcaccgcgcg gtcgaccagt tcggcgagtt cccggccgga
    17221 cggcagttcg atgtggaccg tgctgagccg gggacgcagc agccggccga gcatcaggtc
    17281 gtcggcgccg acgacggccg tctcccgcgg gatgcccact ccttcgtcct gcagcgcgcg
    17341 catcagcagc atcgcgaact cgtcgttgta cgcgaacacg gcgtcgaggc cgagggcccg
    17401 ccagcgcccc gcgaggtcgg ccgcggcctt ctcctcgtag gcgagcggca gttcggtcac
    17461 cgtcgcgtcc gtgccggcca gggcctgccg tacgccgtcg agccggggcc tggagaagat
    17521 ctccaggccg gggtcctcgg gcaccacgac accgacccgg cggtggcccc gggccagcag
    17581 gtgcgcgccg acctgccggc cgaccccgtg gtggtccatg agtaacgcgt gggcgccctc
    17641 gacgcgttcg gggccgaggg tgacgacggc ccgggcgccg gaccgtttga gcacggacac
    17701 gccccgcgga ccgagtccgc cgccgggcac cagcacggcg accggtcgca actcggccca
    17761 ggcgcgggcc gcgtcgtcac cctggacgcc gaggccgccg tactgcacga cggtgtattc
    17821 gagacggctg agcgcccact ggagttcgct gaagaactgg ctgtagagcg ggcccacggg
    17881 cacgtcgggg gcgggcatca ggaccatgcg gctgtgcccg gcgcgcagac tgcgggccgc
    17941 ggcgtgcggc acgtacccga gttcctcggc cgccgcgtgg acacggcggc gggtgggctc
    18001 gctgatccgt acggcgctgg tgttgttgag gacgtaggag acggtcgcgc gggacacacc
    18061 cgccagacgg gccacatcgg cactcgtcgg cacggagcgc tgcgcgggcg acggagcggc
    18121 ggacggtttc ggtatctgca ccatgaggta cggcatcctc gcagaagccg ggggcgggcc
    18181 cggggccggg gggcgccgtg cgcgcgggac gtccggctcc gcccggtcgc gcgcggtgcg
    18241 gcccaagtcg ctttgctact gcggcagttc cgtacgtgtc acgcgtgcga ccaggtcgat
    18301 ccagcccgct tccaggcgct ccagcggcat cccgcactcc ttggtcaggt ggtggatcag
    18361 cgcggggtcg aggtaaccca tcagcgtctg ggccaggaga gtcacgtcgg cgtccggtac
    18421 cgccgccctc agcagcaggc cgacgtggcc ggagaggaag cggtggggcg ggttggagta
    18481 gcggcgggcc ggttccggct gggccgccag ttgcagctcc aggtggtcga ccgcctggcg
    18541 cagagcggcg cacccgaacg cccgcagccg ctcgaccggc ggcgcgccgg ggcccagcgg
    18601 cggcgggccg ctgaggaagg cggcctgtag ctgtttggcg gagtggtcga gcagcgccat
    18661 cagcaggccg gtgcggtcgc cgaagcggcg gaagacggtt cctttgccga ccgaggccgc
    18721 gacggccacc gcctccatcg tgacgccggc cgctccgtgc ttctcgacca ggagtgtggc
    18781 cgcttccagc agccgggcgc ggttgcgtgc cgcgtcggcg cgcaggcagg gctcgtccgc
    18841 cgcggagccg agctccagga gcacgggctc gtcggtcggc tcctggtgct tcggaaaggg
    18901 cggcagggag gcggacatga agacagcgta acgcggggga agaaaactgg accgtggtcc
    18961 gtttggctgg tagaacttta aacggacctc ggtccggatc gtaacggcaa tgtttcaccc
    19021 tccttggagt cccccatgtc tgttcgcatt ctcgcgctcg tcggcagcct tcgcgccggc
    19081 tcccacaacc gccagctcgc cgaggcagcc gtcaagctcg cgcccgaggg cgccgagatc
    19141 gagctgttcg agggtctggc cgacattccc ttctacaacg aggacatcga cgtcgagggc
    19201 gacgtcccgg ccgccgccgc ccggctgcgt gaggccgtgg ccggcgtcga cgccctgctg
    19261 ctcttctcgc ccgagtacaa cggcaccatc ccggccgtcc tgaagaacgc catcgactgg
    19321 ctgtcccgcc cgttcggtgc cagctccatc agcgccaagc cgctggccgt ggtcggcacc
    19381 gcctacggcc agttcggcgg cgtctgggcg caggacgaga cccgcaaggc cgcgggtatc
    19441 gccggtgcca aggtccttga ggacgtcaag ctctccatcc ccggctcggt cgtccgcttc
    19501 gccgagacgc acccctccga cgacgccgag gtcaccgccc agctcgccga ggtcatcgcg
    19561 cagctgcacg gccaggcgaa ctcgcccgtc gccgcctgac cacgacacgt tccgcggccc
    19621 gcgcgtcgca cgtgacacgg aagggggccg gagccgagag ctccggcccc cttccgtgtc
    19681 gccgctccac ccggtgggca tccgcgccgc cgccggtcgc ctccgtacgg tgccggctca
    19741 gccgagtccg gcgagtcgcc cgaccacggg gccggccgtg cgctcgatcc actcggcggg
    19801 ctcgtccacg cgcgggccca ggatcacggt ctcgatgccc agcttcgcgt agtcctccat
    19861 ctcccgtgtg aacgcgtcga gttcggcctg gctgccggga ttgcccgagt gcagcatcgt
    19921 cttgcggatg tccgcgtact cgcggcccac ggcgtcgcag tgcccgcgca ggacgtccag
    19981 cttgtgcccg atctcctcgg gggtcgaggc gaacaggttg caggcgtccc cgtaccgggc
    20041 gaccagtcgg agtgtcttct tctcaccgct gccgccgatc atgatctccg ggcgcggcgt
    20101 gctcaccgga gccggtacgc agagggtctc ggcgagccgg tagtgcttgc cctcgaacgg
    20161 cccgttcgcc tgcgggtccc acatctgcag acagatccgc agcgtctcct ccagccgttc
    20221 gaagcgctcc gcgagcgccg ggaacgggac accgaggccc gcgtgctcgc ggtcgtacca
    20281 ggccgcgccg atccccaggg tggcccggcc gccggacagc acgtcgagcg tggtggcgat
    20341 cttggcgagc agtccgggac ggcggtaggt caccccggtc acgagcgtcc cgagccggac
    20401 ggtggaggtg tgggccgcga ggaagccgag ggtcgtgtac gactccagca tggcgtcctc
    20461 ggcgccgccg ttgaactcca tctggaagta gtggtccatg accgacagcc agctcacccc
    20521 cgcggcctcg gcggcggcgc ccgcggcggc cagttcgggg ccgagcgcca ccgcgccgcc
    20581 ggggtggttg aaccggttga tgtgcacgcc gacccgcatg tccgtctccg tcgccctggg
    20641 atcaccgccg gaccgttgcc gactctcgtg acggtagaac ttgaagagca ctcgaaggca
    20701 aggccggggc gtccgcccga cgcctccgac gggcgaaccg ccttccgcac gaaggaagtt
    20761 gcctctcccg taccgcatgg gccattcgga ggttaccgtg cggtagacat cggggccgcg
    20821 gttcccgtcc acgcgccgta gtctgggctc atgaacgacg cgtcgatggt ggggctcatg
    20881 gggcgggtca ccggcacggt gggacccggg ctcgtcggcg aggtgatcgt ccgggtccgg
    20941 ggcggcgc
//
