LOCUS       NZ_AP023438            22144 bp    DNA     circular CON 15-DEC-2024
DEFINITION  Micromonospora sagamiensis strain JCM 3310 chromosome, complete
            genome.
ACCESSION   NZ_AP023438
VERSION     NZ_AP023438.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora sagamiensis
  ORGANISM  Micromonospora sagamiensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Micromonosporales; Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 6930736)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu
            Genome Coverage                   :: 62X
            Sequencing Technology :: Illumina HiSeq X Ten; PacBio Sequel II
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014680085.1-RS_2024_12_13
            Annotation Date                   :: 12/13/2024 15:12:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,941
            CDSs (total)                      :: 5,859
            Genes (coding)                    :: 5,751
            CDSs (with protein)               :: 5,751
            Genes (RNA)                       :: 82
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 30 of 108
            Pseudo Genes (incomplete)         :: 88 of 108
            Pseudo Genes (internal stop)      :: 5 of 108
            Pseudo Genes (multiple problems)  :: 15 of 108
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:39:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3228815
            Orig. end                         :: 3250959
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP023438.1.
            Genome sequencing and analysis were conducted under the Global
            Catalogue of Microorganisms (GCM) 10K type strain sequencing
            project (http://gctype.wdcm.org). The genomic data are also
            available at http://gctype.wdcm.org/sequencing/GCM10017556
            Annotated by DFAST v.1.2.7 (https://dfast.nig.ac.jp).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22144
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="15"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22144
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22144
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12144]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12144
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(184..615)
                     /locus_tag="IGA62_RS14115"
                     /old_locus_tag="GCM10017556_28120"
     CDS             complement(184..615)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IGA62_RS14115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10017556_28120"
                     /product="hypothetical protein"
                     /protein_id="WP_145820964.1"
                     /transl_table=11
                     /translation="MKPPVAPLLATATTVTLLAIAAPAQATTAGPRDASATNLGSQATC
                     YGTTSRSYFQTGGWGGQAGPYRTSSRCVDINVRNASAFSTQACVIFIDRTSNCNYWTYL
                     PANSGWTTIATNVRDGVNFKVRFSNSYYQYEPLVAYHAY"
     gene            816..1526
                     /locus_tag="IGA62_RS14120"
                     /old_locus_tag="GCM10017556_28130"
     CDS             816..1526
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007074004.1"
                     /locus_tag="IGA62_RS14120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_28130"
                     /product="DUF2786 domain-containing protein"
                     /protein_id="WP_145820961.1"
                     /transl_table=11
                     /translation="MSDAMLSKVRKLLAKAEDPACTPAESAALTAKATELIARYGVDRA
                     LLAARDPATDPVGDRVVDVLAPYARDKAGLLAAVADPLRCRCVRRREGSGFTMHLFGFA
                     SDLERVDLLFTSLLVQAAHGLAGTPVPAGAHPAAFRRSWLAGFAQVVGERLRAAEAAAV
                     EVAAADGPSVALVLVDRSDRVRRRLDEVYPRLRTAAPRRLAGTGYSAGADAGRRAELGG
                     RTVGGSPRRALGGR"
     gene            complement(1541..2059)
                     /locus_tag="IGA62_RS14125"
                     /old_locus_tag="GCM10017556_28140"
     CDS             complement(1541..2059)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (18-159). E-value:
                     2.3e-09. Score: 29.7. Matches aSDomain:
                     nrpspksdomains_IGA62_RS14125_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018811918.1"
                     /locus_tag="IGA62_RS14125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_28140"
                     /product="SRPBCC family protein"
                     /protein_id="WP_145820959.1"
                     /transl_table=11
                     /translation="MGQEIAEPDAVHQDVDRFSLRSTLVVPASPEEAFAAFTDLTSWWV
                     AEYTWSGPDFLTELGIEPRPGGMLYEIGPHGFRADWGRVLTWDPPRRLVFVWQIGPDRV
                     PVPDPSKASEVEVNVEADGPARTRVTVEHRKFDRHGTAAEGYRQAMTEGWQDMLTRYLH
                     SVRRRPHPA"
     aSDomain        complement(1583..2005)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IGA62_RS14125_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="2.30E-09"
                     /label="IGA62_RS14125_Polyketide_cyc2.1"
                     /locus_tag="IGA62_RS14125"
                     /protein_end="159"
                     /protein_start="18"
                     /score="29.7"
                     /tool="antismash"
                     /translation="SLRSTLVVPASPEEAFAAFTDLTSWWVAEYTWSGPDFLTELGIEP
                     RPGGMLYEIGPHGFRADWGRVLTWDPPRRLVFVWQIGPDRVPVPDPSKASEVEVNVEAD
                     GPARTRVTVEHRKFDRHGTAAEGYRQAMTEGWQDMLT"
     misc_feature    2187..2201
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: strong, score: 20.76"
                     /tool="antismash"
     gene            complement(2236..2709)
                     /locus_tag="IGA62_RS14130"
                     /old_locus_tag="GCM10017556_28150"
     CDS             complement(2236..2709)
                     /EC_number="2.3.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018797113.1"
                     /locus_tag="IGA62_RS14130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_28150"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_145822237.1"
                     /transl_table=11
                     /translation="MGDGHALAVLEIYRLGIATGNATFETEPPTWESFTATRMPGHRWV
                     AVDQSGDVLGWTACSAVSDRCVYAGVVEHSVYVHPDTRGRGVGQGLLQALITSTEQAGI
                     WTIQSGVFPENTASLALHASCGFRTVGTRQRIGRHHGVWRDVTLIERRSPTIT"
     gene            complement(2754..3125)
                     /locus_tag="IGA62_RS14135"
                     /old_locus_tag="GCM10017556_28160"
     CDS             complement(2754..3125)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007459218.1"
                     /locus_tag="IGA62_RS14135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_28160"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_145820956.1"
                     /transl_table=11
                     /translation="MSKQALPVVDLRAVACCPPIAVRPLDAGEAETVAPMFKALGDPVR
                     LRLMSMIASAPEVCVCDLTPAFELSGPTISHHLKVLREAGLVDADRRGTWVWYRVKPEA
                     FRQLGVLLQLPARADETVA"
     misc_feature    3107..3120
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 20.06"
                     /tool="antismash"
     misc_feature    complement(3169..3182)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.31"
                     /tool="antismash"
     gene            3307..3765
                     /locus_tag="IGA62_RS14140"
                     /old_locus_tag="GCM10017556_28170"
     CDS             3307..3765
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018790760.1"
                     /locus_tag="IGA62_RS14140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_28170"
                     /product="ArsI/CadI family heavy metal resistance
                     metalloenzyme"
                     /protein_id="WP_145820954.1"
                     /transl_table=11
                     /translation="MSRVQLALRVSDLEGSVAFYSKLFGTEPAKRRPGYANFAIENPPL
                     KLVLLEGEPDQPTVMDHLGVEVFSTDEVNAATRRLTDAGLVTLEENSTECCYALQDKVW
                     VRGPGNEPWEVYTVKADSPQAEKAIPSACCTPAAEQEPAASGAAANCC"
     gene            complement(3903..4601)
                     /locus_tag="IGA62_RS14145"
                     /old_locus_tag="GCM10017556_28180"
     CDS             complement(3903..4601)
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018826539.1"
                     /locus_tag="IGA62_RS14145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_28180"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_145820952.1"
                     /transl_table=11
                     /translation="MSVSALTPERRAALSRRSLRLAYATAGYNLVEGLVAMAAGAAASS
                     AALVGFGLDSFVEVSSAAVLIWQFRSRVPEDRERLALRLIGVSFFALAAWVTFDALRSL
                     LTAGDADASPVGIGLAVASLIVMPLLVRAKRRTGRELGSATVMADSTQTMLCTYLSAVL
                     LVGLLLNAVLGWSWADPIAALVIAGVAVKEGLEAWRGEHCDDCAPLPVDTAVTGQPAGC
                     TDGCCSDRKA"
     gene            complement(4598..4957)
                     /locus_tag="IGA62_RS14150"
                     /old_locus_tag="GCM10017556_28190"
     CDS             complement(4598..4957)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018795079.1"
                     /locus_tag="IGA62_RS14150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_28190"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_145820950.1"
                     /transl_table=11
                     /translation="MAIDCSPGLAPAVALFRSLGDPARLAIVRRLASGEARVVDLTDEL
                     GLAQSTVSKHLACLRDCGLIDYRVEGRQSFYALTRPELLDLLRSAEQLLATTGEAVALC
                     PVYGVPDGSPAAVGA"
     gene            5040..5366
                     /locus_tag="IGA62_RS14155"
                     /old_locus_tag="GCM10017556_28200"
     CDS             5040..5366
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IGA62_RS14155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10017556_28200"
                     /product="hypothetical protein"
                     /protein_id="WP_145820948.1"
                     /transl_table=11
                     /translation="MSVTDPDPLWIAVRLVVVVLSLGMVVFGVRVAVSRRFPVAWVRAA
                     RLPASQRSQPVRIGGGQALIGASLLLQQAPFLVPMPYPVGAALFVVALLLAAAGVGWFV
                     LRRD"
     tRNA            complement(5584..5657)
                     /anticodon=(pos:complement(3234436..3234438),aa:Phe,
                     seq:gaa)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="IGA62_RS14160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GCM10017556_t00530"
                     /product="tRNA-Phe"
     gene            complement(5584..5657)
                     /locus_tag="IGA62_RS14160"
                     /old_locus_tag="GCM10017556_t00530"
     tRNA            complement(5721..5797)
                     /anticodon=(pos:complement(3234576..3234578),aa:Asp,
                     seq:gtc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="IGA62_RS14165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GCM10017556_t00540"
                     /product="tRNA-Asp"
     gene            complement(5721..5797)
                     /locus_tag="IGA62_RS14165"
                     /old_locus_tag="GCM10017556_t00540"
     tRNA            complement(5830..5902)
                     /anticodon=(pos:complement(3234681..3234683),aa:Glu,
                     seq:ttc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="IGA62_RS14170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GCM10017556_t00550"
                     /product="tRNA-Glu"
     gene            complement(5830..5902)
                     /locus_tag="IGA62_RS14170"
                     /old_locus_tag="GCM10017556_t00550"
     gene            complement(6056..6871)
                     /locus_tag="IGA62_RS14175"
                     /old_locus_tag="GCM10017556_28210"
     CDS             complement(6056..6871)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730889.1"
                     /locus_tag="IGA62_RS14175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_28210"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_145820946.1"
                     /transl_table=11
                     /translation="MTSRVLAAAGAALMLLLAGCGEATQVRSVGPTAPVFSPPAGATPS
                     ADPPESPRPSGVPRPSPSPSKTGPKSTRTPLPPGLRRSTGTRGVALTFDDGPDPVWTPK
                     VLEQLRRHRVTATFCVVGTRVRKHPGLVARIVREGHQLCNHSWHHDVDLGGRPRAEIRA
                     DLDRTTRAIRAAVPGAKVPFYRQPGGRWTPEVVAVARDLGMTPLHWNVDPQDWAKPTAT
                     TIVARVKDATRPGSVVLLHDGGGNRAATVAACPGLIADIKRRYGVTRLR"
     gene            complement(6951..7886)
                     /locus_tag="IGA62_RS14180"
                     /old_locus_tag="GCM10017556_28220"
     CDS             complement(6951..7886)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018255064.1"
                     /locus_tag="IGA62_RS14180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_28220"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_145820944.1"
                     /transl_table=11
                     /translation="MADEALSAGAVARRLGVAVTTLRTWHQRYGLGPSEHIPGHHRRYT
                     PADLARLEIMRRLTAEGVTPAEAARWARQSPAGTPPARRSTSTVRDGGGAAIPVGRAGP
                     AARGLARAAMRLDSVTVSRTIDESIATDGVVATWEGLLRPVLTGIGERHTATAALVEVE
                     HLFSRCVTEAFAVVARANPTGGLPRILLSCTDDEQHTLPLEALAAALAEAGVGCRMLGA
                     RVPVAALVAAVTRTAPAAVVLWSHLRATADPTQLTAVLAVPRRPLLVLAAGPGWWDDTL
                     PAGVVRPVSLAEAVSLALAVRDSLDRSPPG"
     gene            complement(7876..8487)
                     /gene="idi"
                     /locus_tag="IGA62_RS14185"
                     /old_locus_tag="GCM10017556_28230"
     CDS             complement(7876..8487)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="idi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283449.1"
                     /locus_tag="IGA62_RS14185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_28230"
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_145820942.1"
                     /transl_table=11
                     /translation="MTSRETHLVELVHDDGTTDGAATVAEAHQPPGRLHRAFSVLLVDP
                     SGRVLLQRRAAAKTRFPLRWANACCGHPAPGESLVEAANKRLSEELGTGPVELTEVGVY
                     VYYAEDPTTGRVEFEYDHVLRADVPADLPLRPDPTEVAEVRWIDPVHLETELDVDPRAY
                     APWLGGVVNRLLRPSGPGPDGAGPPSGTPTDDASERSGGR"
     gene            complement(8474..9967)
                     /gene="crtI"
                     /locus_tag="IGA62_RS14190"
                     /old_locus_tag="GCM10017556_28240"
     CDS             complement(8474..9967)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018222034.1"
                     /locus_tag="IGA62_RS14190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_28240"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_145820940.1"
                     /sec_met_domain="DAO (E-value: 1.7e-18, bitscore: 65.8,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTVDGRTDRVVVVGAGLGGLACALHLAGSGRQVTVLEREPVPGG
                     RAGRLGADGYEFDTGPTVLTMPDLIAEALGAVGEELADWMELTPLDPAYRAYYPDGSTL
                     DVITDTTRMAAEISRVCGPREADGYLRFVDYARELWRLERADFIERNLDAPTDLLTGNL
                     LKLLASGAFRRLQTKINQFFRDPRTQRIFSFQAMYAGLAPHDALAIYAVIAYLDSVAGV
                     YFPRGGIHAVSRGLAGAAEKHGVRIRYGTTVERVETSGGRATGVLTTDGERIPADVVVL
                     NPDLPVAYRDLLPPARQRRLTYSPSCVVLHVGSTQGYSKIAHHNIHFGRAWKGTFDEVI
                     RRGELMTDPSLLVTNPSRTDPSVAPAGRHTYYVLAPVPNLDRAPFDWRGGLARRYADEL
                     MATLEERGYVGFADGVEVCEIVTPAEWADQGMAAGTPFAAAHSLFQTGPFRPSNLHRTL
                     SNVVFVGSGTQPGVGVPMVLISGKLAARRITGGAARDLP"
     gene            complement(10001..11155)
                     /locus_tag="IGA62_RS14195"
                     /old_locus_tag="GCM10017556_28250"
     CDS             complement(10001..11155)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019870059.1"
                     /locus_tag="IGA62_RS14195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_28250"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_145820938.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.9e-45, bitscore:
                     152.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANDAVAGNAPRTATIRPAGGDDPVTGVLAAYTKDLVMAVEETLS
                     AFLATEVDSLAEIDAAMGAFAATARDLVLAGGKRVRPTFAYWGWRGVAGAEAELPPVLP
                     ALSALELLHTFALVHDDVMDASDTRRGLPTAHRAMAAEHRAAGRRGDPDRFGEAVAVLI
                     GDLCLVWADRLLSRTALPAARLMQTRRCYDQMRVETVAGQYLDVLGENEPANWSLDRAL
                     RVARYKTASYTVQRPLLYGAALGGVGVDAPLVEAYTRYGLAVGEAFQLRDDLLGVYGDP
                     ALTGKPAGDDLRSGKPTVLLMLARQLAGPVQRARLDRAGADLDEDGVAELAGLVAATGA
                     VGRVEQMISERVSEALAALDVADLDETVRSALTGLATASARRWA"
     misc_feature    complement(11156..11174)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.96"
                     /tool="antismash"
     gene            11221..12144
                     /locus_tag="IGA62_RS14200"
                     /old_locus_tag="GCM10017556_28260"
     CDS             11221..12144
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454366.1"
                     /locus_tag="IGA62_RS14200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_28260"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_145820935.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.4e-115,
                     bitscore: 382.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.1e-66,
                     bitscore: 222.6, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTNLTAAYDRCRELHRRHGRTYYLATRLLPAWKRRHVHALYGFT
                     RYADEIVDRTEELSPADRAARLDEWSARFLAGLHGEPVDDPLLPAVLHTIAVFDLDRAD
                     FASFLRSMAMDLTVTSYRTYDDLLDYMEGSAAVIGTMMLPILGSAAPAAAREPARQLGL
                     AFQLTNFIRDVAEDLDRGRTYLPDEDLAKFDVTREDLLAAKARGRGTPRIRDLVEYEIS
                     RAQAHYEAAAPGIVLLNPGSQACMRTAYALYGGILDEVAAQDYDVFTRRARVPRRQRVA
                     VATRALLAPAGTPVTVPGPRTVPPRR"
     misc_feature    complement(11222..11236)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.93"
                     /tool="antismash"
     gene            complement(12280..13392)
                     /locus_tag="IGA62_RS14205"
                     /old_locus_tag="GCM10017556_28270"
     CDS             complement(12280..13392)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473461.1"
                     /locus_tag="IGA62_RS14205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_28270"
                     /product="serine hydrolase"
                     /protein_id="WP_145820933.1"
                     /transl_table=11
                     /translation="MRARFAAVHDCFHDLFDSGRETGAALAVRYDGQPVLDLTGGSTRP
                     AGAGSTPPADGPHGAGGGAWRPDTLVNVYSVGKPVVALCLLLLVDRGRLDLDDPVARHW
                     PGFRTPATVRQVLAHTAGLPVFPVPRPAAALGDWALLVGDLAAAEPEWEPGTVAGEHAL
                     TYGHLVGELVRRVDGRTVGRFLAEEIAGPWRLDLGFGLDTVDQRRCADLSYGEAGWPVT
                     TLGVPGSLRERALANPAGCLDAAVLNSPLWRGAEIPAVNLHATATGLARLYGGLLAGGT
                     LDGVRLFSADLVAEATRVQYDGPDLLLESRTRWTLGMQYEEDGSWGMGGIGGSCAWADP
                     VRGYTLAYTTARLAGFDRVEALVDALHSCL"
     gene            complement(13450..13944)
                     /locus_tag="IGA62_RS14210"
                     /old_locus_tag="GCM10017556_28280"
     CDS             complement(13450..13944)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072602.1"
                     /locus_tag="IGA62_RS14210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_28280"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_145820931.1"
                     /transl_table=11
                     /translation="MPPAPEPHLEKITPGNVEVACDLRVRPDQEHLVEPVARSLAEAYA
                     WPDVAWPRLIYDGDEPVGFLMGFFRIPWREDSPGDLRSGLWRLNIAAGRQGRGYGCFAV
                     RAVAEEAARRGEQRIYTTWEPGDDGPERFYLRLGFQPTGELSGGQTVGALDLSAPDTGN
                     R"
     gene            14071..15546
                     /locus_tag="IGA62_RS14215"
                     /old_locus_tag="GCM10017556_28290"
     CDS             14071..15546
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454372.1"
                     /locus_tag="IGA62_RS14215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_28290"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_145820929.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.5e-44, bitscore:
                     150.1, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEPQQVDVVVVGLGVGGEEVAGRLAEAGLDVVGVERGLVGGECP
                     YWGCIPSKMMIRAANALAEARRVDGLAGSAEVRPDWAPVARRIREEATANWDDTAAVDR
                     FTGKGGRFVRGTGRLAGPGRVAVDDQVFQARYGIVVGVGTRPSVPPVEGLAGTPYWTNR
                     AAIEVAELPASLLVLGGGAIGLELAQVFARFGVRVTVVEASDRVLAVEEPEASEVAAAA
                     LRADGVEIHTGVRAKRVDHDEVAGFTLRADGGAGFTAERLLVVTGRRAHLDELGLDTVG
                     LDAGQRYLPVDDRMRAGEGIWAVGDVTGEGAFTHIAMYQAEIVVRDLLDHVARQRGGPD
                     ASGTASAIGGAIGAAGAGGGSTPGPADSVPRADYRALPRVTFTDPEVGAVGLTERQARE
                     RGINVQVGFAPLSSSTRGWIHRVGDEGFIKLVADADRGVLVGATSVGPAGGEVLSALVV
                     AVHAAVPVGRLRHMIYAYPTFHRAIRTALDDLS"
     misc_feature    15641..15659
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.58"
                     /tool="antismash"
     gene            15771..16808
                     /locus_tag="IGA62_RS14220"
                     /old_locus_tag="GCM10017556_28300"
     CDS             15771..16808
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014695282.1"
                     /locus_tag="IGA62_RS14220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_28300"
                     /product="CapA family protein"
                     /protein_id="WP_232625009.1"
                     /transl_table=11
                     /translation="MPGRTVTVLGAGDILVHPELWDQARRDGRGQLDFAPMLAPARSAV
                     ESADLALCHLETPVAPPGGPYIGFPRFSVPREVVQGIKSVGYDGCSTASNHSIDQGYDG
                     VKRTLDALDAAGLGHTGTYRTARDATRPRIYPVDGVRIAHLSYTKSFNGLRPAAGQAWI
                     ANLIDTDKIKKDAARARAAGAEIVVVSLHWGTEYEHEPDADQQTWAREVAELRNVDLVF
                     GHHAHVVQPVERIGDKWIVYGMGNQIARHAEPVNANRDGAMVRVTFGPAGVAKRWKVRA
                     VEALPTFVDLNPDIRLIDLERALADPALPPGRRRIYEAAVERIQGNLLTRAAGEAGLVV
                     RGTGG"
     misc_feature    16964..16978
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.67"
                     /tool="antismash"
     gene            17026..19161
                     /locus_tag="IGA62_RS14225"
                     /old_locus_tag="GCM10017556_28310"
     CDS             17026..19161
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014695283.1"
                     /locus_tag="IGA62_RS14225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_28310"
                     /product="HAMP domain-containing protein"
                     /protein_id="WP_232625010.1"
                     /transl_table=11
                     /translation="MQLLLWRRRALEQQLPAAAFPAGSGAPSLVYLWASMFVVVAVVLG
                     FALSAQRGVLPAVIDSQDDVVTKLASTISVSTRAWSEELDRTVADRGTGTDAQLLSRVV
                     GDSTSVSGAAVVETASRRPLATKGTAVPAGVLPAEIPLDSAFGVTTPDGPVVLRAYRLD
                     ERRTLVAVHPLTLRNLRLNPDAGHGVYVLTPDGGTSLMQGANAVGQEHLPVVFQGLAGS
                     TSRQSREVVIEEWPDRRLVVSSAPVGDTGLVVVSLLAAEVTGGASLPTGLLLGLTLLMF
                     AVSSFLLMRVSLVRPIRVLLAQAKADACGGLTPHRRPARIAEAQRIARALALTSGDRPP
                     AERRWRPTVLQGLTAATVVALLWPAGAVVLALQTPAPTVPTQLVRDQENRAEEASFALG
                     SALDAGLGTVSRISRSVDPADRERTARVLRRELAEEHRLRALYLVDRDGKVLASAGREP
                     LRTAEPLPGEVGIQLDDAVSRLPVVFAYNLRSDGFAVVGEFDPDRLVGLVRRVDGRVRV
                     VDAELRTILDSEGFRAYQPVGEDLVAAAAVEALPGTTVGHSTTADGAPALVAASGLTAP
                     ATVAHLEWSVVVEQDIAALRLPEMVERRWTLLVAGAMVGIILLTHMWQLYIYVRPVQRL
                     ASFADRMSRGEIDVPVPPQRHDDIGAVAMCLEICRQVRHTGSARFGGAIRLRGSDLNRT
                     AVLPLVRRPVGARREKG"
     gene            19163..20440
                     /gene="pgsB"
                     /locus_tag="IGA62_RS14230"
                     /old_locus_tag="GCM10017556_28320"
     CDS             19163..20440
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0070501 - poly-gamma-glutamate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="pgsB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018732657.1"
                     /locus_tag="IGA62_RS14230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_28320"
                     /product="poly-gamma-glutamate synthase PgsB"
                     /protein_id="WP_145820925.1"
                     /transl_table=11
                     /translation="MFYLYTVYALCCLALLVAGVVEQRNHYRNLGRIPHRVLVNGIRGK
                     SSITRLCAGALRGGGKVVVAKTTGTAARFIFPDASEEPVHRKFGIANVVEQIGIVRRAA
                     VYHPDSLVIECMAVMPALQEINQSKLIRSNIGVLCNVREDHLAEMGPTLDDVARSLSRS
                     MPVGGICITAEKDRLAILEQEAARRDCRLIAVDPESVTDREMAGFGWITFKENVAIALA
                     VAEQLGVDRRSALAGMWAAPPDPGVLSVARVLYEGKRIRFANIFAANDPESTFMNIEQL
                     EKQRLIGRPLIMVINCRPDRVERNGQMGALSGRVQPQRIVLIGEMTRSARVTVPAELQE
                     RVVDLGGKLPPERLLADVMTATAADASIVAVGNIHGQGEVLLHELAALPSWSPQGQAGS
                     ESMLRTPTVPGFDTDAQTVLLERIRR"
     gene            20437..20922
                     /locus_tag="IGA62_RS14235"
                     /old_locus_tag="GCM10017556_28330"
     CDS             20437..20922
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018732658.1"
                     /locus_tag="IGA62_RS14235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_28330"
                     /product="poly-gamma-glutamate biosynthesis protein
                     PgsC/CapC"
                     /protein_id="WP_145820923.1"
                     /transl_table=11
                     /translation="MTFGGELSAQLATACLGIGLVFALLCYLTTNLSPGGMITPGWIAL
                     ALIEDPLQAGVIVVMTVVTYGLTLLMQRMVILYGKRLFAAIVLLSVFLQLTLFVIVQKD
                     LPLLFAHQTLGFVAPGLIAYQLVRQPPKATVVATAIVTAITYGVAFSGVVAGLVPVT"
     gene            20945..21991
                     /locus_tag="IGA62_RS14240"
                     /old_locus_tag="GCM10017556_28340"
     CDS             20945..21991
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018732659.1"
                     /locus_tag="IGA62_RS14240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_28340"
                     /product="C40 family peptidase"
                     /protein_id="WP_145820921.1"
                     /transl_table=11
                     /translation="MNYRTYSQTQAALVTLAAFALLTGAGFVTYLVARPSTDRIVLSLG
                     AAAVPQSVVRTDTGYSYRRLSAPDRTQIVDASGKVLATMTDGARTVHLHGPERIFAEPR
                     FTKAKVHTDLWVRLAPKEWYAGAEQDAWFTTWFSKARTDRSPDVLGVAMEYTYVSSPKK
                     DAQGRQYSGDAAFGPLSDSDPDGRAENSDFYDYLGVSWTFPDKKEKPAAAHIRSLDCSG
                     FLRMVYGYRLGYPLRGTNEAGPGLPRRAYAMASVGPGAQLMPNTGKRARDLDRLLPGDL
                     LFFNAGPVQGANIEHSGMYLGVDDRGHHRFISSRTTANGPTMGDLGGESTLDGTGYWAT
                     RFRTARRI"
ORIGIN
        1 ccaggccaac tacgacaccc gctgggtggc ccgtttcctc agcgcgtacg ccaaccgcga
       61 cccggagacc ggcgaggcgc tcttcggtgc cgcgatcgcc gacgggctgc tccccgactg
      121 cctgctcacg ctggccggtt cggcggtggc caccctctac ggcccgaagc gcccgcccgc
      181 cggtcagtag gcgtggtagg ccaccagcgg ctcgtactgg tagtagctgt tcgagaagcg
      241 gaccttgaag ttcaccccgt cccggacgtt ggtggcgatc gtcgtccagc cggagttggc
      301 cggtaggtac gtccagtagt tgcagttgct ggtgcggtcg atgaagatca cgcaggcctg
      361 ggtgctgaag gcgctggcgt tgcggacgtt gatgtcgacg caccggctgc tggtccggta
      421 cgggccggcc tgcccgcccc agccgccggt ctggaagtag gaccggctcg tggtgccgta
      481 gcaggtcgcc tggctaccga ggttggtggc ggaggcgtcg cgcgggccgg cggtggtggc
      541 ctgggcgggt gcggcgatgg ccagcaacgt gaccgtcgtc gcggtggcca gcaggggagc
      601 gaccggtggt ttcatgggct tctccaaccg tgtactgacc gctggaggtc gatccttcgc
      661 ggaccgtgac gatggtactg atcaatgcgc tgctccgctg tccccgccag ccgcaccgcg
      721 tccacgtcca gctccggtcg acgccggata ccggaaccgg ccaccgaccc ggtgcggccc
      781 ggctccgcgc cggacggtgt ggtagctgtg gtggcatgtc cgacgccatg ctcagcaagg
      841 tgcgcaagct gctcgccaag gcggaggacc cggcctgcac ccccgccgag tcggccgcgc
      901 tgaccgccaa ggcgaccgag ttgatcgccc gctacggggt cgaccgggcg ttgctcgccg
      961 cccgcgaccc ggccaccgac ccggtcggcg accgggtggt ggacgtcctc gccccgtacg
     1021 cccgggacaa ggccggtctg ctcgcggcgg tggccgaccc gctgcgctgc cgctgcgtgc
     1081 ggcggcgcga gggcagcgga ttcaccatgc acctgttcgg gttcgccagc gacctggagc
     1141 gggtcgacct gctcttcacg tccctgctgg tgcaggccgc gcacggcctg gccggcacgc
     1201 ccgtgccggc cggtgcccac ccggccgcct tccgccgttc ctggctggcc gggttcgcgc
     1261 aggtggtcgg ggagcggttg cgagcggccg aggcggcggc ggtggaggtc gcggcggcgg
     1321 acggcccctc ggtggcgctg gtactggtgg accggtcgga ccgggtgcgg cggcgactcg
     1381 acgaggtgta tccccggctg cggaccgccg cgccccggcg gctggccggc accggctact
     1441 ccgccggagc ggacgcgggg cgccgggccg agctgggcgg acggacggtc ggcgggtcac
     1501 cccgccgcgc gctcgggggc cgttgaggcg gcccggcggg tcaggccggg tgcggacggc
     1561 ggcggacgga gtgcaggtag cgggtgagca tgtcctgcca tccctcggtc atcgcctgcc
     1621 ggtaaccctc cgcggcggtg ccgtgccggt cgaacttccg gtgctcgacg gtgacccggg
     1681 tccgtgccgg gccgtcggcc tcgacgttca cctcgacctc gctggccttc gacgggtccg
     1741 gcacgggaac ccggtccggg ccgatctgcc agacgaagac cagccggcgg ggcggatccc
     1801 aggtgaggac ccggccccag tcggcccgga agccgtgcgg accgatctcg tagagcatgc
     1861 cgccggggcg gggctcgatg cccaactcgg tgaggaagtc cggcccggac caggtgtact
     1921 cggcgaccca ccaactggtc aggtcggtga aggcggcgaa cgcctcctcc ggtgaggcgg
     1981 ggacgacaag agtgctgcga agggagaaac ggtcgacgtc ctgatggacg gcgtccggct
     2041 cagcgatctc ctgccccata ggcccggacc ctaccggctg ccgcctcgac gtgcagcgac
     2101 cttagttcgt cgggcggcgc gggatggcct cgcgaaatcc ggataaaaac caacaagaat
     2161 cgtcgcccca cgctgtcccg taggtgatca cctccgtcga tcacaagtac gtaaaccacc
     2221 gtccgggcgg gtccgtcagg tgatcgtggg actgcgacgc tcgatgaggg tgacgtcccg
     2281 ccagacaccg tggtggcggc cgatgcgctg gcgggtgccg acggtacgga agccgcagga
     2341 ggcgtgcagg gcgaggctgg cggtgttctc cgggaacacg ccggactgga tggtccagat
     2401 cccggcctgc tcggtcgagg tgatcagggc ctggagcagg ccctgaccga ctccccggcc
     2461 ccgggtgtcg gggtggacgt agacggagtg ttcgacgacg ccggcgtaga cgcaccggtc
     2521 ggacaccgcc gagcaggcgg tccaccccag gacgtcgccg ctctggtcga cggccaccca
     2581 gcggtggccc ggcatgcggg tggcggtgaa gctctcccag gtcggtggct cggtctcgaa
     2641 ggtcgcgttt ccggtggcga tgccgagacg gtatatctcc aggaccgcga gggcgtgccc
     2701 gtcgcccatg gccgtgatcg tgatgccccc ggcggcggtc gtcccggtgg cgttcacgcg
     2761 acggtctcgt cggccctggc gggcagttgc agcaggacgc cgagttggcg gaacgcctcc
     2821 ggcttcaccc ggtaccagac ccaggtgccg cgtcggtcgg cgtcgaccag gccggcttcc
     2881 cggagcacct tcaggtggtg ggagatggtc ggcccggaca gctcgaacgc gggggtcaga
     2941 tcgcagacgc agacctcggg cgccgaggcg atcatcgaca tcagtcgcag ccggaccggg
     3001 tcgcccaggg ccttgaacat cggcgccacg gtctccgcct cgccggcgtc cagtggacgt
     3061 acggcgatcg gcgggcagca ggccaccgcc cgcaggtcca ccaccggcaa cgcttgtttc
     3121 gacatgcgcc taggttgaca gatatcgaaa cagggtgcaa cagttggctt gcttcgaaaa
     3181 gtatctaggc aagggtggtg gtgacccggc tgctgcgccg gccgtcgctc cgccgtgccg
     3241 atgccgatgc aaccgcacgc cgcgctgacc ccagcgcgcg tccgtcgacc aaccaggagg
     3301 agaaccatgt cccgtgtcca gctcgccctg cgcgtgtccg acctcgaagg ctccgtcgcc
     3361 ttctactcga agctgttcgg caccgagccg gccaagcgtc gccccggcta cgccaacttc
     3421 gccatcgaga acccaccgct gaagctcgtc ctgctcgaag gcgaacccga ccagccgacc
     3481 gtcatggacc acctgggcgt cgaggtgttc agcaccgacg aggtcaacgc cgccacccgg
     3541 cgcctcaccg acgccggcct cgtcaccctg gaggagaaca gcaccgaatg ctgctatgcc
     3601 ctccaggaca aggtctgggt gcgtggcccc ggcaacgagc cctgggaggt ctacaccgtc
     3661 aaggcagact ccccccaggc ggagaaggcc atcccgagcg cctgctgcac cccggccgcc
     3721 gagcaggagc ccgcagccag cggcgccgcc gcgaactgct gctgaccggg tcgcgtgcgc
     3781 gcccgtcccg gtcccgagcg ggcgcgcacg cccgggcgtc gtgagggccg tgcggcgctc
     3841 gcggcaacgg tgcggccctc acggggcgtc cggcgctcgc ggtggcggtg cggccgaccc
     3901 gactacgcct tccggtcgga gcagcagccg tcggtgcagc ctgcgggttg gccggtgacg
     3961 gcggtgtcga cgggcagcgg ggcgcagtcg tcacagtgct cgccgcgcca ggcttccagg
     4021 ccctccttca ccgctacccc ggcgatgacg agcgcggcga tcggatcggc ccaggaccag
     4081 ccgaggacgg cgttgaggag cagaccgacg aggagtaccg ccgacagata ggtgcacagc
     4141 atggtctgcg tggagtcggc catgaccgtt gccgagccga gttcgcgacc ggtgcgccgc
     4201 ttcgcccgta cgagcagtgg catcacgatc agcgacgcca cggccaggcc gatgccgacc
     4261 ggactggcgt cggcgtcccc ggcggtcagc agcgaccgta gggcatcgaa cgtcacccac
     4321 gcggccaggg cgaagaagga gaccccgatc agccgcagcg ccagtcgttc ccggtcctcg
     4381 ggtacccggg agcggaactg ccagatcagt acggccgcgc tggacacctc gacgaacgag
     4441 tcgagaccga agccgaccag cgccgccgag gaggccgccg cgccggcggc catcgccacc
     4501 aggccctcca ccaggttgta gcccgccgtg gcgtacgcga gccggagact gcgtcgcgac
     4561 agtgccgccc ggcgctccgg ggtcagcgcg gagacgctca tgcgccgacc gccgccgggg
     4621 agccgtccgg cacgccgtag accgggcaca gggcgaccgc ctcgccggta gtggcgagga
     4681 gctgttccgc cgaacgcagc agatccagca gctccggccg ggtcagcgcg tagaacgact
     4741 ggcgaccctc gacccgatag tcgatcagcc cgcagtcccg gaggcacgcg agatgcttcg
     4801 agacggtcga ctgcgccaac cccaactcgt cggtcaggtc cacgacccgc gcctcaccgg
     4861 aggccaggcg acgcacgatc gccaaccgtg ccggatctcc gagggaccgg aacaacgcca
     4921 cggcaggggc gagccccgga gaacaatcaa tcgccactag gcgatgatag ccggactggg
     4981 cgatggaatc gtacgcggcg acacgttgat ccttgacatc ccgctgaatg atgggccgtg
     5041 tgagcgtgac tgacccggat ccgttgtgga tcgccgtacg cctcgtggtc gtcgtcctca
     5101 gtctgggcat ggtggtgttc ggcgtccgcg tcgccgtgtc gcgacggttt cccgtggcct
     5161 gggtgcgggc tgcgcgcctg ccggcaagcc agcggtccca gccggtccgt attggcggcg
     5221 gtcaggcgct gatcggcgcg agcctgctgc tccagcaagc accgttcctc gttcccatgc
     5281 cctacccggt cggggccgca ctgttcgtgg tggcactgct acttgctgcg gctggggtgg
     5341 ggtggttcgt cctccggcgg gactagccgt caactgccgt cagcgccgtc cgtctcgtcg
     5401 aagaagtcgc gggcggaagc gctcctcccg gggctcgtcc tcgtcctggt cgccggactc
     5461 cggccacccc tggaagacgc aacgcaatca cccgtgcgat tcctcacgga ctcaccctga
     5521 acgcaacagc gccgaccggc gtttccgctg gtcggcgctg tggtagcccg gcgaaaggct
     5581 atgtggccag gggcggggtc gaaccgccga ccttccgatt ttcagtcgga cgctcgtacc
     5641 aactgagcta cctggccgta cccgggtgag tttaccctcc ccgacgcaga acgccgcgcg
     5701 gtgagacgcg gcgtcagcgt tggcggtcct gacgggactt gaacccgcga cctccgcctt
     5761 gacagggcgg cgagcactcc aactgctcca caggacctag ctcgtactgc ctccggctgg
     5821 gccggatcgt gcccccaacg ggattcgaac ccgtgctacc gccttgaaag ggcggcgtcc
     5881 tgggccgcta gacgatgagg gcggccccgc catcattgca cactcgcaac ttcaagcgga
     5941 cttgctccca tccggccccg ccggaggctt gcaaagcata cgtgatgagc cgccgggcaa
     6001 caaaatcggt atcgccccgg ccgtagcttc gcccgaaacg gcaggtcaga ggggttcagc
     6061 gcagtctggt cacgccgtac cggcgcttga tgtcggcgat caggccggga caggcggcca
     6121 ccgtggcggc ccggttcccg cccccgtcgt gcagcagcac caccgagccg gggcgggtcg
     6181 cgtccttcac ccgcgccacg atcgtcgtgg ccgtcggctt cgcccagtcc tgcggatcga
     6241 cgttccagtg cagcggggtc atgccgaggt cccgggccac cgccaccacc tccggcgtcc
     6301 accggccgcc cggctggcgg tagaagggca ccttcgcccc gggcaccgcc gcccggatcg
     6361 cccgggtggt gcggtccaga tcggcgcgga tctcggcccg gggtcggccg cccaggtcca
     6421 cgtcgtggtg ccagctgtgg ttgcagagct ggtgcccctc gcgcacgatc cgggccacca
     6481 ggccggggtg cttgcggacc cgggtaccca ccacgcagaa ggtggcggtg acccggtgcc
     6541 gacgcaactg ctccaggacc ttcggcgtcc agaccgggtc ggggccgtcg tcgaaggtga
     6601 gcgccactcc ccgggtgccg gtgctccggc gcagccccgg tggcagtggg gtgcgggtcg
     6661 acttcgggcc ggtcttcgac ggcgacggcg agggccgcgg tacgccggac ggcctcgggg
     6721 actccggcgg gtcggcggac ggtgtcgctc cggcgggcgg cgagaagacc ggtgcggtcg
     6781 ggccgacgga gcggacctgg gtcgcctcgc cgcagccggc gagcaggagc atcagggcgg
     6841 caccggccgc agccaggacg cgtgaggtca tcgtcgttgc tcccgagagg gggtcggggt
     6901 cacgggcgcc ccgacgttac gccccgtccg gtgaaggtga caccccccgg tcagccgggc
     6961 ggtgaccggt ccaacgagtc ccgtaccgcc agggccagcg agaccgcctc ggccagcgac
     7021 accggccgga ccactcccgc cggaagggtg tcgtcccacc agccgggacc tgcggcgagc
     7081 accagcaggg gtcgacgggg caccgcaagc accgcggtga gctgggtcgg gtcggcggtc
     7141 gcgcgcaggt gcgaccagag caccacggcg gccggggcgg tccgggtgac cgcggccacc
     7201 agcgccgcca cgggtacccg cgcgccgagc atgcggcagc cgacacccgc ctcggcgagc
     7261 gcggcggcga gcgcctccag gggcagggtg tgctgctcgt cgtcggtaca ggagagcagg
     7321 atgcggggga ggccaccggt cgggttggcc cgggcgacca cggcgaacgc ctccgtcacg
     7381 caccgggaga agaggtgctc gacctcgacc agcgcggcgg tcgcggtgtg ccgctcaccg
     7441 atgccggtga gcaccgggcg cagcagccct tcccaggtgg cgacgacgcc gtcggtggcg
     7501 atcgactcgt cgatcgtccg gctgacggtg accgagtcca gccgcatggc ggcgcgggcc
     7561 agcccacggg cggccggacc ggcccggccg accgggatgg ccgctccgcc gccgtcccgg
     7621 acggtggagg tgctccggcg cgccggtggt gtgccggccg gggactgccg ggcccagcgg
     7681 gcggcctcgg ccggggtgac cccctcggcg gtgagccggc gcatgatctc cagccgggcc
     7741 aggtcggccg gggtgtagcg gcggtggtgg ccggggatgt gctcgctggg tccgagtccg
     7801 tagcgctggt gccaggtccg cagcgtggtc accgcgaccc cgagccgccg cgccacggct
     7861 cccgcgctca gcgcttcatc ggccacccga ccgctccgac gcgtcgtccg tcggcgtgcc
     7921 ggacggaggt ccggccccgt cgggtccggg cccgctgggg cgcagcaggc ggttcaccac
     7981 cccgccgagc cacggcgcgt acgcgcgggg gtcgacgtcg agttccgtct ccagatggac
     8041 cgggtcgatc cagcgcacct cggcgacctc ggtcgggtcc ggccggagtg ggaggtcggc
     8101 cggcacgtcg gcgcgcagca cgtggtcgta ctcgaactcg acgcggccgg tggtcgggtc
     8161 ctcggcgtag tagacgtaca cgccgacctc ggtcagctcg accgggccgg tgccgagctc
     8221 ctcgctgagc cgcttgttgg cggcctcgac gagcgactcg cccggggccg ggtggccaca
     8281 gcaggcgttc gcccagcgca gcgggaaccg agtcttggcg gcggcccgcc gttgcagcag
     8341 tacccggccg gacgggtcga ccagcagcac cgagaaggcc cggtgcaacc gccccggcgg
     8401 ctggtgcgcc tccgccacgg tggccgcgcc gtccgtggtg ccgtcgtcgt ggaccagctc
     8461 gaccaggtgt gtctcacggg aggtcacggg cggcacctcc ggtgatacgg cgggcggcga
     8521 gcttgccgga gatcagcacc atcggcaccc cgacgcccgg ctgggtgcct gatcctacaa
     8581 aaaccacgtt cgacagtgtg cggtgcaggt tcgaggggcg gaacggcccg gtctggaaca
     8641 ggctgtgcgc ggcggcgaac ggggtgccgg cggccatgcc ctggtcggcc cactcggccg
     8701 gggtgacgat ctcgcagacc tcgacgccgt cggcgaagcc gacgtagccc cgttcctcca
     8761 gggtcgccat caactcgtcg gcgtagcggc gggccagacc gccccgccag tcgaagggtg
     8821 cccggtcgag gttcggcacc ggggcgagca cgtagtaggt gtgccggccg gcgggggcga
     8881 ccgacgggtc ggtgcggctc gggttggtga ccagcaggga cgggtcggtc atcagctcgc
     8941 cgcgccggat cacctcgtcg aaggtgccct tccaggcccg gccgaagtgg atgttgtggt
     9001 gggcgatctt cgagtacccc tgggtcgacc cgacgtgcag caccacgcag gacggtgagt
     9061 aggtcagccg acgctggcgg gccgggggga gcaggtcgcg gtacgccacg gggaggtccg
     9121 ggttgagcac caccacgtcg gccgggatcc gctcgccgtc ggtggtgagc acaccggtgg
     9181 cccggccgcc ggaggtctcg acccgctcga cggtggtgcc gtaccggatc cggacgccgt
     9241 gcttctcggc ggccccggcc aggccccggg agacggcgtg gatgccgccg cgcgggaagt
     9301 acacgccggc caccgagtcg aggtacgcga tgaccgcgta gatggccagc gcgtcgtgcg
     9361 gggcgaggcc ggcgtacatc gcctggaagg agaagatccg ctgggtgcgc gggtcccgga
     9421 agaactggtt gatcttggtc tgaagtcggc ggaacgcccc gctggccagc agtttcagca
     9481 ggttgccggt gagcaggtcg gtcggcgcgt cgaggttgcg ctcgatgaag tcggcccgtt
     9541 ccaaccgcca cagctcgcgg gcgtagtcga cgaagcggag gtatccgtcg gcctcccggg
     9601 ggccgcagac ccgggagatc tccgccgcca tccgggtggt gtcggtgatc acgtccagcg
     9661 tcgagccgtc cgggtagtac gcccggtacg ccggatcgag cggggtcagc tccatccagt
     9721 cggccagctc ctcgccgacc gcgccgagcg cctcggcgat caggtcgggc atggtgagca
     9781 cggtcgggcc ggtgtcgaac tcgtacccgt cggcaccgag ccggcccgcg cgaccaccgg
     9841 gcaccggttc gcgttccagc acggtgacct gccggccgct gccggccagg tgcagggcac
     9901 aggccaggcc ccccagcccc gcgccgacga ccacgacccg gtcggtacgt ccgtcaacgg
     9961 tccgcatgcg gaccccctcc ctcgggaaaa cgactgccca tcatgcccac cgtcgggcgc
    10021 tggcggtggc gagtccggtc agcgcggacc gcaccgtctc gtccaggtcg gcgacgtcga
    10081 gagcggccag cgcctcggac acccgctcgg agatcatctg ctcgacccgc ccgaccgcgc
    10141 cggtcgccgc gaccagcccg gccagctcgg cgaccccgtc ctcgtcgagg tcggcgccgg
    10201 cccggtcgag tcgggcgcgc tggaccgggc cggcgagctg ccgggcgagc atgagcagca
    10261 ccgtcggctt gccgctgcgc aggtcgtcgc cggccggctt gccggtgagg gcgggatcgc
    10321 cgtagacgcc gagcaggtcg tcacggagct ggaacgcctc gccgaccgcc agcccgtacc
    10381 gggtgtacgc ctcgaccagc ggcgcgtcca caccgacgcc gccgagggcc gccccgtaca
    10441 gcaacgggcg ctgcacggtg tagctggcgg tcttgtagcg ggcgacccgc agcgcccggt
    10501 cgagcgacca gttcgccggc tcgttctcgc cgagcacgtc gagatactgc ccggcgaccg
    10561 tctccacccg catctggtcg tagcagcgcc gggtctgcat caaccgggcc gccgggagcg
    10621 cggtgcggga gagcaggcgg tccgcccaga ccaggcagag gtcgccgatc aggacggcca
    10681 ccgcctcacc gaagcggtcg gggtcgcccc ggcgtccggc cgcccggtgc tcggcggcca
    10741 tcgcgcggtg cgcggtcggc aggccccggc gggtgtcgga ggcgtccatc acgtcgtcgt
    10801 ggaccagggc gaaggtgtgc agaagttcca acgcggagag cgcggggagt accggtggca
    10861 gttcggcctc ggcgccggcc acgccgcgcc agccccagta ggcgaacgtc ggacggaccc
    10921 gcttcccgcc ggccagcacg aggtcacggg cggtcgcggc gaaggcgccc atcgctgcgt
    10981 cgatttcggc gagtgagtcg acttcggtgg ccaggaaggc ggagagggtc tcctccacgg
    11041 ccatgaccag gtccttggtg tacgcggcga gaaccccggt gaccgggtcg tcgcctcccg
    11101 ccggccggat cgtcgccgta cggggcgcgt taccggcaac tgcgtcgttg gccatggtgg
    11161 cgagcgtacc ctagggttac gagttgcgtc gattggtgcg tcgatttcaa ggaggggccg
    11221 gtggacacga acctcaccgc tgcctacgac cggtgccgcg agctgcacag acgtcacggt
    11281 cgcacctact atctcgccac ccgcctgctc cccgcttgga aacggcggca tgtgcacgcc
    11341 ctgtacggct tcaccaggta cgccgacgag atcgtcgacc gcaccgagga gctgtccccg
    11401 gccgaccgcg ccgcccggct cgacgagtgg tccgcccgct tcctcgccgg cctgcacggc
    11461 gaaccggtgg acgacccgct gctgccggcc gtcctgcaca ccatcgccgt cttcgacctg
    11521 gaccgggccg acttcgcgtc gttcctgcgc agcatggcga tggatctgac cgtcacctcg
    11581 taccgcacct acgacgacct gctcgactac atggagggct cggccgccgt catcggcacg
    11641 atgatgctgc cgatcctcgg cagcgccgcg ccggccgccg cccgggaacc ggcccgccag
    11701 ctcggcctgg ccttccagct caccaacttc atccgggacg tcgccgagga cctcgaccgg
    11761 ggccgcacct acctgcccga cgaggacctg gccaagttcg acgtcacccg ggaggacctg
    11821 ctcgccgcca aggcccgggg ccggggcacc ccgaggatcc gggacctggt cgagtacgag
    11881 atcagccgcg cccaggccca ctacgaggcc gccgcacccg ggatcgtcct gctcaacccc
    11941 ggttcgcagg cgtgcatgcg gaccgcgtac gccctctacg gcgggattct cgacgaggtg
    12001 gccgcccagg actacgacgt gttcacccgg cgggcgcgcg taccgcgtcg gcagcgggtg
    12061 gcggtggcga cgcgggcgct gctcgccccg gccggcaccc cggtcaccgt ccccgggccc
    12121 cgcaccgtgc cgccccgccg gtaggggtcg tccggctcgg gcgcggcggg ctgaggtgcc
    12181 tgcaggggca ccttgcaggc gcattttgat gagcaggggt cccctgctac cacctcggcc
    12241 ggggcggcag gtgcgccccg gtgagccgga ggggccgtct cacaggcagg agtgcagggc
    12301 gtcgacgagt gcctcgaccc ggtcgaaacc ggccagccgc gcggtggtgt acgccagcgt
    12361 gtagccccgg accgggtcgg cccaggcgca actgccgccg atcccgccca tgccccagct
    12421 accgtcctcc tcgtactgca tgccgagggt ccaccgggtt cggctctcca ggagcaggtc
    12481 cgggccgtcg tactgcaccc gggtcgcctc ggcgaccagg tcggcgctga acaggcgtac
    12541 cccgtcgagg gtgccgccgg ccagcagccc gccgtagagc cgggccagcc cggtcgcggt
    12601 ggcgtgcagg ttcaccgccg ggatctccgc gccgcgccag agcgggctgt tcagcaccgc
    12661 cgcgtcgagg caaccggcgg ggttggcgag cgcccgctcc cgcagcgatc cgggcacgcc
    12721 cagcgtggtc accggccagc ccgcttcgcc gtacgacagg tcggcgcagc gccgctggtc
    12781 gacggtgtcc agtccgaagc cgagatccag ccgccagggg ccggcgatct cctcggcgag
    12841 gaaccggccg accgtgcgtc cgtccacccg gcggacgagt tcgccgacca ggtgcccgta
    12901 cgtcagcgcg tgctcgcccg cgacggtgcc cggctcccac tccggctcgg cggcggcgag
    12961 gtcgccgacg agcagcgccc agtcgcccag cgcggcggcc ggccggggca ccgggaagac
    13021 cggcaggccg gcggtgtggg cgagcacctg ccggacggtg gccggggtgc ggaaccccgg
    13081 ccagtgccgg gccaccggat cgtccaggtc gagccggccc cggtccacca gcagcagtag
    13141 gcagagggcg accaccggct tgccgaccga gtacacgttg accagggtgt ccggtcgcca
    13201 cgcgcctccg ccggcaccgt gcggtccgtc agcgggcggt gtgctgccgg cgccggccgg
    13261 tcgggtcgag ccgccggtca ggtcgagcac cggctggccg tcgtaccgca cggccagtgc
    13321 cgcgccggtc tcccggcccg agtcgaacag gtcgtggaag cagtcgtgga ccgccgcgaa
    13381 gcgtgcgcgc atcgggccac ggtagggcgc cgccccggtt ccgcgtcgca cggtctgtcg
    13441 gcccggccgt cagcggttgc cggtgtccgg cgcggacagg tcgagggcgc cgacggtctg
    13501 cccgccgctg agttccccgg tcggctggaa cccgagccgc aggtagaacc gctccggccc
    13561 gtcgtcgccc ggttcccagg tcgtgtagat ccgctgctca ccacgccgtg ccgcctcctc
    13621 ggcgaccgcc cggacggcga agcagccgta tccgcgcccc tgccggccgg cggcgatgtt
    13681 cagccgccac agtccggagc gcaggtcgcc cggactgtcc tcgcgccagg ggatccggaa
    13741 gaagcccatc aggaagccga ccggttcgtc gccgtcgtag atcagccggg gccaggcgac
    13801 gtcgggccac gcgtacgcct cggccagcga ccgggcgacc ggctcgacca ggtgctcctg
    13861 gtcggggcgg acgcgcaggt cgcaggccac ctcgacgttg ccgggagtga tcttctcaag
    13921 gtgtggctcg ggtgcgggcg gcatggggcc ggaccctacc ggcccccgac caccggctcg
    13981 acctgattcg gtggtcgaag gcgctggccg cccttgtcgg cgtacccgac tcgttggcgc
    14041 ccgccgggag ccctgggaca tgctgtcggc atgacggagc cgcagcaggt ggacgtggtc
    14101 gtggtcgggc tcggcgtcgg cggcgaggag gtggccgggc gactcgccga ggcgggcctc
    14161 gacgtcgtcg gcgtcgagcg ggggctggtc ggtggcgagt gcccgtactg gggctgcatc
    14221 ccgagcaaga tgatgatccg ggcggcgaac gcgctggccg aggcgcggcg ggtcgacggg
    14281 ctggccgggt cggccgaggt ccggccggac tgggctccgg tggcccgccg gatccgcgag
    14341 gaggcgaccg cgaactggga cgacaccgcc gccgtggacc gtttcaccgg caagggcggg
    14401 cgcttcgtcc gggggaccgg ccggctggcc ggcccgggtc gggtcgccgt cgacgaccag
    14461 gtcttccagg cccggtacgg gatcgtcgtg ggggtgggta cccggccgtc ggtgccgccg
    14521 gtcgaggggt tggccgggac gccgtactgg accaaccggg cggcgatcga ggtggccgag
    14581 ctgccggcgt cgctgctggt gctcggcggc ggcgcgatcg ggctggagct ggcccaggtg
    14641 ttcgcccggt tcggggtgcg ggtgacggtg gtcgaggcgt ccgaccgggt gctcgccgtc
    14701 gaggagccgg aggcgtccga ggtggccgcc gccgccctgc gcgccgacgg cgtggagatc
    14761 cacaccggcg tccgggcgaa gcgggtggac cacgacgagg tggccgggtt caccctgcgg
    14821 gccgatggag gtgccgggtt caccgccgag cggctgctgg tggtcaccgg tcgccgggcc
    14881 catctcgacg agttggggct ggacaccgtc ggcctcgacg ccgggcagcg gtacctgccg
    14941 gtcgacgacc ggatgcgggc cggcgagggg atctgggcgg tcggtgacgt caccggcgag
    15001 ggggcgttca cccacatcgc gatgtaccag gcggagatcg tcgtgcgtga cctgctcgac
    15061 cacgtcgctc ggcagcgggg cgggccggac gccagcggca ccgccagtgc gatcggcgga
    15121 gcgatcggtg ccgccggagc gggcggcggg tccaccccgg gtccggccga cagcgtgccc
    15181 cgggccgact accgggcgct gccccgggtc accttcaccg acccggaggt gggggcggtc
    15241 gggttgaccg aacgtcaggc ccgggaacgg gggatcaacg tccaggtcgg cttcgcgccg
    15301 ctctcctcct ccacccgggg ctggatccac cgggtcggcg acgaggggtt catcaagctc
    15361 gtcgcggacg ccgaccgggg cgtgctggtc ggcgcgacgt cggtcggccc ggccggtggc
    15421 gaggtgctgt ccgcgctggt ggtggcggtg cacgcggcgg ttccggtggg ccggctccgg
    15481 cacatgatct acgcgtaccc gaccttccac cgcgccatcc ggacggccct ggacgacctg
    15541 agctgaccct gtccggaggt gaaacgggac gtcggcgtgg tgccggctag ccttgcgcgg
    15601 tgccgaagaa ccctctctcc ctccggcggt tccccggtcc ggtgcgaacg ctcctgagct
    15661 gcctcaccgc agtggcgttg gccctgaccg ggatctacct ggtgggtccg tggtcgagcg
    15721 ggtcgcccgt gtcgacgggc cggccccggc caatcgggaa acccgtcgaa gtgccgggac
    15781 gcaccgtcac cgtgctgggt gcgggcgaca tcctcgtcca ccccgagttg tgggaccagg
    15841 cccggcggga cggccgtggg cagttggact tcgcgccgat gctggcaccg gcccgctccg
    15901 cggtggagag cgcggacctg gcgctgtgcc acctggagac cccggtcgcg ccgcccggag
    15961 gcccgtacat cggctttccg cggttcagcg tgccccggga ggtggtgcag ggcatcaaga
    16021 gcgtggggta cgacggctgc tcgaccgcct cgaaccacag catcgaccag ggctatgacg
    16081 gggtgaagcg caccctggac gcgctggacg ccgccggtct cgggcacacc ggcacgtacc
    16141 gcaccgcccg tgacgccacc cgcccccgga tctatccggt cgacggggtg cggatcgccc
    16201 acctgagtta caccaagagt ttcaacgggc tgcgtccggc ggccgggcag gcctggatcg
    16261 ccaacctgat cgacaccgac aagatcaaga aagacgccgc gcgggcccgc gcggccggcg
    16321 cggagattgt cgtggtcagc ctgcactggg gcaccgagta cgaacacgag cccgacgccg
    16381 accagcagac ctgggcccgt gaggtggcgg aactgcgcaa cgtcgacctc gtcttcggtc
    16441 atcacgcaca cgtcgtccag ccggtcgagc ggatcggcga caagtggatc gtctacggga
    16501 tgggcaacca gatcgcccgg cacgcggaac cggtcaacgc caaccgcgac ggagccatgg
    16561 ttcgggtgac gttcggaccg gccggggtgg cgaaacggtg gaaggtgagg gccgtcgagg
    16621 cgcttcccac cttcgtcgat ctgaaccccg acatccgcct gatcgacctg gaacgggcgt
    16681 tggccgatcc cgccctgccc cccggtcgcc gacggatcta cgaggctgcc gtcgagcgta
    16741 tccaggggaa tctgctgacg agagcggccg gcgaggccgg tctggtggtg cgcggaacgg
    16801 ggggttgaag cgcctcaccc cgctcgttcc gaggccccgg ccggagcctg agcccgcgcc
    16861 tcgcctctgc gagagttgct aacattcgcc gcgtcgtctg ctgtcccagg tcagtggccc
    16921 acggctcagg tacgggtgga tgttcacggg ggaaggcgaa tggtcgtgtc agtaaatcct
    16981 gggcacttca cgcgctcgcc cggcggcgcc ggaccggacg accggatgca gctactgctc
    17041 tggcggcgtc gggctctgga acagcagctc ccggcggcgg ccttcccggc cggcagcggt
    17101 gcgccgtcgc tggtctatct gtgggcttcg atgtttgtcg tcgtcgcggt ggtgctcggg
    17161 ttcgcgctca gcgcccagcg gggcgtcctg cccgcggtga tcgactcgca ggacgacgtg
    17221 gtcaccaagc tggcctccac catctcggtg tccacccgag cgtggtcgga ggagctggac
    17281 cgaacggtgg ccgaccgggg aaccggcacc gacgcccaac tgctgagccg ggtggtcggc
    17341 gacagtacct cggtcagcgg tgccgcagtg gtggagaccg cgtccagacg gccgcttgcc
    17401 accaagggca ccgccgtacc cgccggtgtg ctccccgccg agatcccgct cgactcggcg
    17461 ttcggggtga ccacgccgga cggacccgtg gtgctgcgcg cgtaccggct ggacgagaga
    17521 cggacgctgg tggcggtgca tccgctcacc ctgcgaaacc tgcgattgaa ccccgacgcg
    17581 ggacacgggg tctacgtgct caccccggac ggcgggacga gcttgatgca gggagccaac
    17641 gcggtggggc aggagcacct acccgtcgtc ttccagggtc tggccgggag cacctcgcgg
    17701 cagagccggg aggtggtcat cgaggagtgg ccggaccgga ggttggtcgt gtcgtccgcg
    17761 cccgtcggcg acaccggtct ggtggtggtc tccctgctgg ccgcagaggt caccgggggt
    17821 gcctcgttgc ccaccggact gctgctgggg ctcaccctgc tgatgttcgc cgtgtcgagc
    17881 ttcctgctca tgcgggtgtc gctggtccgt ccgatccggg ttctgctcgc gcaggccaag
    17941 gcggacgcct gcggcggcct gaccccgcac cgcaggccgg cgcggatcgc cgaggcccaa
    18001 cggatcgccc gggctctcgc gctgacctcg ggggaccggc cgcccgccga gcggcggtgg
    18061 cggcccaccg tgttgcaggg gttgaccgcc gcgacggtgg tcgcgctgct ctggccggcc
    18121 ggggccgtgg tgctggctct ccagactccc gcccccaccg ttccgacgca gctcgtccgg
    18181 gaccaggaga accgggccga ggaggcgagt ttcgcgctgg gcagcgctct cgacgccgga
    18241 ctggggacgg tgtcccggat ctcccggtcg gtcgatcccg ccgaccggga gaggaccgct
    18301 cgggtgctac gccgggaact cgccgaggag catcgactcc gggcgctcta cctggtggac
    18361 cgggacggga aggtgctggc ctcggcgggg cgggagccgt tgcgtaccgc cgagccgctt
    18421 cccggtgagg tcgggatcca gctcgacgac gccgtctccc gcctgcccgt cgtgttcgcc
    18481 tacaacctgc gctccgacgg cttcgccgtg gtgggcgagt tcgacccgga ccgcctggtg
    18541 gggctggtcc ggcgggtcga cggccgggtc cgggtggtgg acgccgaact gcggaccatc
    18601 ctcgactcgg agggcttccg ggcgtaccag ccggtcgggg aggacctggt cgccgcagcg
    18661 gcggtcgagg cgctgcccgg caccaccgtc ggccactcga cgaccgccga cggggctccc
    18721 gccctggtcg ccgcgtcagg gctgaccgca ccggccaccg tggcccacct ggagtggtcg
    18781 gtggtcgtgg agcaggacat cgccgcactg cgcctgccgg agatggtgga acggcggtgg
    18841 acgctgctcg tcgcgggtgc gatggtgggg atcatcctgc tcacccacat gtggcagctc
    18901 tacatctacg ttcggccggt acagcggctg gcctccttcg ccgaccggat gagccggggc
    18961 gagatcgacg tgccggtgcc gccgcagcgc cacgacgaca tcggagcggt ggcgatgtgc
    19021 ctggagatct gccggcaggt ccggcacacc ggttccgccc ggttcggcgg cgccatccgg
    19081 ttgcgcggtt cggacctgaa ccgtacggcc gtcctgcccc tggtccggcg gccggtcggc
    19141 gcccggaggg agaagggctg agatgttcta cctctacacc gtctacgcac tctgctgcct
    19201 ggcgctgctc gtggccggtg tcgtcgagca gcgcaaccac taccgcaacc tcggccgcat
    19261 cccgcaccgg gtactggtga acggtatccg gggcaagagt tcgatcaccc ggctctgcgc
    19321 gggcgcgctg cgcggcggcg gcaaggtggt ggtcgccaag acgacgggca ccgctgcccg
    19381 gttcatcttc ccggacgcca gcgaggagcc ggtgcaccgg aagttcggca tcgccaacgt
    19441 ggtcgagcag atcggcatcg ttcgccgggc cgccgtctac catcctgact cgctggtcat
    19501 cgagtgcatg gcggtgatgc ccgcgcttca ggagatcaat cagagcaagc tgatccggtc
    19561 gaacatcggg gtgctctgca acgtccggga ggaccacctc gccgagatgg gaccgacact
    19621 ggacgacgtg gcccggtcgc tgagccggtc gatgccggtg ggcgggatct gcatcaccgc
    19681 cgagaaggac cggctggcga ttctcgaaca ggaggccgcc cggcgtgact gccggttgat
    19741 cgcggtggac ccggagtcgg tcaccgaccg ggagatggcc ggcttcggtt ggatcacctt
    19801 caaggagaac gtggcgatcg cgctcgccgt ggccgagcag ctcggcgtcg accggcgcag
    19861 cgcgctggcc gggatgtggg cggctccacc ggacccgggt gtcctctcgg tggcccgggt
    19921 gctgtacgag ggcaagcgga tccgcttcgc caacatcttc gccgccaacg atcccgagtc
    19981 caccttcatg aacatcgagc agctcgagaa gcagcggctg atcgggcgtc cgctgattat
    20041 ggtgatcaac tgtcgcccgg accgggtgga gcgcaacggc cagatgggcg cgctctccgg
    20101 ccgagtccag ccgcagcgca tcgtgctgat cggcgagatg acccgcagcg cccgggtgac
    20161 cgtgcccgcc gaactccagg agcgggtggt cgacctcgga gggaagctgc ccccggaacg
    20221 gttgctcgcc gacgtgatga ccgccaccgc ggcggacgcg tcgatcgtcg ccgtgggcaa
    20281 catccacggt cagggcgagg tgctgctgca cgagctggcc gcgctgccca gctggagtcc
    20341 gcaggggcag gccgggtccg agtcgatgct gcggacgccg accgtgccgg ggttcgacac
    20401 cgatgcccag accgtgctgt tggaaaggat ccgtcggtga ccttcggagg agagctcagc
    20461 gcgcaactcg ccaccgcctg cctcggcatc gggctggtct tcgcgctgct ctgctatctg
    20521 accaccaacc tctcaccggg cggcatgatc acgccgggct ggatcgcgtt ggcattgatc
    20581 gaggacccgc tccaggcggg cgtgatcgtg gtgatgaccg tggtcacgta cgggctcacg
    20641 ctgctgatgc agcggatggt gatcctctac ggcaagcggc tcttcgccgc gatcgtgctg
    20701 ctgagcgtat tcctccagct gacgctcttc gtgatcgtgc agaaggacct gccgctcctc
    20761 ttcgcacacc agaccctggg cttcgtcgcg ccggggctga tcgcctacca gctcgtccga
    20821 cagccaccca aggcgaccgt cgtggccacc gcgatcgtca ccgcgatcac ctacggcgtc
    20881 gcgttcagcg gtgtcgtcgc cggcctcgtc ccggtcacct gaccggccaa cggaggaaca
    20941 gtcgatgaac taccggacct actcccagac ccaggccgca ctggtcaccc tcgccgcgtt
    21001 cgcgctgctg accggtgccg gcttcgtcac ctacctcgtc gcccggccct ccaccgaccg
    21061 gatcgtgctg tcgctcggag ccgccgccgt gccgcagagc gtggtccgga ccgacaccgg
    21121 gtacagctac cgccgcttga gcgctcccga ccggacccag atcgtcgacg cctccgggaa
    21181 ggtcctcgcc acgatgaccg acggggcccg gacggtgcac ctgcacggac cggagcgcat
    21241 cttcgcggaa ccccggttca ccaaggccaa ggtgcacacc gacctgtggg tacggctcgc
    21301 accgaaggag tggtacgccg gcgcggagca ggacgcctgg ttcaccacct ggttcagcaa
    21361 ggcccgcacg gaccgctctc cggacgtgct cggggtggcc atggagtaca cctacgtctc
    21421 gtcgccgaag aaggacgcgc agggccggca gtactcgggc gacgccgcct tcgggcccct
    21481 ctccgacagt gatccggacg gtcgggcgga gaactccgac ttctacgatt atctcggtgt
    21541 ctcatggacc ttccctgaca agaaggagaa gccggccgct gcgcacatcc gtagcctcga
    21601 ctgctcggga tttctgcgga tggtgtacgg ctaccggctc gggtacccgc tgcgcgggac
    21661 gaacgaggcg ggcccggggt tgccccggcg ggcgtacgcc atggcctcgg tcggccccgg
    21721 ggcccaactg atgccgaaca ccggcaagcg ggcccgggac ctggaccggt tgctccccgg
    21781 ggaccttttg ttcttcaacg cggggccggt gcagggggcg aacatcgagc actccggcat
    21841 gtacctcggt gtggacgacc gggggcacca ccggttcatc tcgagccgta ccaccgcgaa
    21901 cgggccgacc atgggtgacc tcggcggcga gtcgacgctc gacggcaccg gttactgggc
    21961 gacccggttc cgcaccgccc ggcggatctg accggcgcgg gcctaccggg aagaaggggc
    22021 ggggctcagc cccgcagccg ctccgcgagt acctgcgcga ccaggtcccg cccgaccgcg
    22081 tcccgtcgca ccgaccagct cagttccagg tggacgaagg cgctgtccag cccggcgctc
    22141 gccc
//
