LOCUS       NZ_AP023438            21869 bp    DNA     circular CON 15-DEC-2024
DEFINITION  Micromonospora sagamiensis strain JCM 3310 chromosome, complete
            genome.
ACCESSION   NZ_AP023438
VERSION     NZ_AP023438.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora sagamiensis
  ORGANISM  Micromonospora sagamiensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Micromonosporales; Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 6930736)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu
            Genome Coverage                   :: 62X
            Sequencing Technology :: Illumina HiSeq X Ten; PacBio Sequel II
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014680085.1-RS_2024_12_13
            Annotation Date                   :: 12/13/2024 15:12:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,941
            CDSs (total)                      :: 5,859
            Genes (coding)                    :: 5,751
            CDSs (with protein)               :: 5,751
            Genes (RNA)                       :: 82
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 30 of 108
            Pseudo Genes (incomplete)         :: 88 of 108
            Pseudo Genes (internal stop)      :: 5 of 108
            Pseudo Genes (multiple problems)  :: 15 of 108
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:39:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 905071
            Orig. end                         :: 926940
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP023438.1.
            Genome sequencing and analysis were conducted under the Global
            Catalogue of Microorganisms (GCM) 10K type strain sequencing
            project (http://gctype.wdcm.org). The genomic data are also
            available at http://gctype.wdcm.org/sequencing/GCM10017556
            Annotated by DFAST v.1.2.7 (https://dfast.nig.ac.jp).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21869
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="8"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21869
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21869
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11869]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11869
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(57..72)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.78"
                     /tool="antismash"
     misc_feature    58..71
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.23"
                     /tool="antismash"
     gene            184..1194
                     /locus_tag="IGA62_RS03570"
                     /old_locus_tag="GCM10017556_07270"
     CDS             184..1194
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013088.5"
                     /locus_tag="IGA62_RS03570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_07270"
                     /product="DMT family transporter"
                     /protein_id="WP_198501198.1"
                     /transl_table=11
                     /translation="MRTPRPALGVVMVLCSGVLFAVNGTVSKLVLRTGIDAPQLTLLRA
                     AGAFTVLLALSALLRPGIRRLRVTAGQVPLLVGYGLTGFFLVPMLYFVAISRLPVGIGL
                     LFEYSAPLLVALWARFGQRHPVRPRLWAGLALSLVGLACVAEIWGEFTLDGLGVLAGLG
                     AAFFLAFYYVLGARGVEGRDTVSLCTWAFGAAAVAGLLTRAVTGVGDWTPLAGTSRGVP
                     VVLLLGYVVVLGSVVPYLLVAGAMRHLPATSVGIVGMVEPVIASAVAWVTLGATEALNA
                     AQLGGGLLVLVGVALAETARVAPGRTPPSAETDRPGPPDVVAVVTTGPAEPGRRT"
     gene            1271..1411
                     /locus_tag="IGA62_RS03575"
                     /old_locus_tag="GCM10017556_07280"
     CDS             1271..1411
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IGA62_RS03575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10017556_07280"
                     /product="hypothetical protein"
                     /protein_id="WP_186499755.1"
                     /transl_table=11
                     /translation="MQPHPTVRAVQDARDATTARDGSGGLAPLGHPALPRMTAGIPAGV
                     A"
     gene            1534..2265
                     /locus_tag="IGA62_RS03580"
                     /old_locus_tag="GCM10017556_07290"
     CDS             1534..2265
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007463074.1"
                     /locus_tag="IGA62_RS03580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_07290"
                     /product="monooxygenase"
                     /protein_id="WP_190289292.1"
                     /transl_table=11
                     /translation="MVTLHVWRVGRSDLPRVLPRMAFGPRWLRATDGVRFAKLLGTGTG
                     TGFGPGDVDPTRWAALTVWTSAEAAAGFDDSPVGRSWARLARATVRLDLRPVASRGEWS
                     RRRPFGDPAGGRVTGRVTGPVLALTRARLRPRRALTFWRAVPPVAAALHHAPGLLARFG
                     VGEAPLGWQGTVSLWRDPASLVEFAYRHPEHRAAIARTPTEGWYAEELFARFEVRAVTG
                     DRAVLGWTGDDDTETVEGGHA"
     gene            2262..2864
                     /locus_tag="IGA62_RS03585"
                     /old_locus_tag="GCM10017556_07300"
     CDS             2262..2864
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018806047.1"
                     /locus_tag="IGA62_RS03585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_07300"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_145816257.1"
                     /transl_table=11
                     /translation="MRLVRWTPDDLVRRLDDVVAVYGEAMGYRPDLLESRRGYIATHVR
                     RPGFRAVASLTSEGHLAGFGYGYLGTPGQWWHDQVSRALDPTRRGIWLTHCFEVVELHV
                     RPSAQGHGLGAGQLRVLLTMAEGSTTLLSTPEADEERSRAWRLYRRFGFVDVLRNFHFP
                     GDERAFGVLGRTLPLPPPAPSGPTASAGPAVSGPYPS"
     gene            2963..3766
                     /locus_tag="IGA62_RS03590"
                     /old_locus_tag="GCM10017556_07310"
     CDS             2963..3766
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785286.1"
                     /locus_tag="IGA62_RS03590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_07310"
                     /product="carotenoid biosynthesis protein"
                     /protein_id="WP_145821822.1"
                     /transl_table=11
                     /translation="MSWVLLGVLVLAQIGYPLTGGGTRAALTVATVVLGYLLSVGHALL
                     TRGPRTAAALVAVATGGGFAIEALGVATGFPFGSYDYSGQLGPKLAGVPLIIPLAWTWM
                     AWPAWLAAVRLVRPGVRRVALAAVGLATWDLFLDPQMVAEGYWRWRDATPALPGLPGVP
                     VSNYLGWLLFGVLMMTLLRPLAGASADRTGPADHPMYALYLWTYFSSVLAHAVFLGLPA
                     SALWGAAGMAVAAVPLAVTLARGHRRRPPAGTGNGSGQRRVDATA"
     gene            3763..4902
                     /locus_tag="IGA62_RS03595"
                     /old_locus_tag="GCM10017556_07320"
     CDS             3763..4902
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013735114.1"
                     /locus_tag="IGA62_RS03595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_07320"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_145816256.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.3e-14,
                     bitscore: 52.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGPVVAVLVPLAVLAALTGHTLVNATRWLRRPADRPAEVDEPVA
                     VLLPLRDEAARVTPCLRALLAQRGVPEMRIVVLDDGSTDGTAEVVRAVVDGDPRVTLLA
                     GVPPPPGWLGKPHACHQLAQRADPAATALVFVDADVVLAPDAVAAAVAELRAARVTLLS
                     PYPRILVTTVGDRLVQPLLQWLWLTFLPLRAMERSARPSLAAAGGQFLVVDRAGYRAAG
                     GHAAVRDRVLEDIELARAVKRAGGRIALADGSRLADCRMYDTWPQLRDGYTKSLWASFG
                     HPGAAAAVVALLGLLYVAPPLLVGAALLVGAPTVATLAGTGYLLGVAGRVVSARATGGR
                     WWPDALAHPVSVVVLGWLTIRSYHLRKRRRLSWRGRPVG"
     misc_feature    4912..4932
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 19.2"
                     /tool="antismash"
     gene            4916..6415
                     /locus_tag="IGA62_RS03600"
                     /old_locus_tag="GCM10017556_07330"
     CDS             4916..6415
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014441607.1"
                     /locus_tag="IGA62_RS03600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_07330"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_145816255.1"
                     /sec_met_domain="DAO (E-value: 7.7e-09, bitscore: 34.0,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARVVVVGAGVGGLATAARLAAAGHEVTVFEQADTVGGKLGRYTH
                     DTPAGSFHFDTGPSLLTLPEVFTELFEATGAKLDEYLDLVPLDPIVRHVFPDGTTPGGG
                     TTLDSCADPVEFTERIGAAFGERSAADWRGLWRRAGRVWETSWQHVLRRPVDSPRDLAA
                     LAWRLGDLAAIAPGRTLRGLGRRHLSDPRMRMLLDRYATYTGADPRRAPAALVAVPYAE
                     LAFGGWYLRGGLGTLADALLSRCLDLGVVVQTGTAVTRIDAAGGRVHGVRLRGIAAPVP
                     ADVVVANVDALTVYRDLLPSPGRLAGLADRSLAGFVLLLGVRGPTGLAHHNVFFPRDYD
                     AEFDAVFGDPGRGVRARPAVDPTVFVTVADDAVVRPADHEAWFVLVNAARHGTATSAVD
                     WRRPGLAEAYADRILDVLAERGIDVRDRLLFREIRTPADLGSATGAPGGAIYGTAGGLL
                     RPANRAPAYGVHLVGGSTHPGGGLPMVTLSARIVADRIGPA"
     gene            complement(6607..7320)
                     /locus_tag="IGA62_RS03605"
                     /old_locus_tag="GCM10017556_07340"
     CDS             complement(6607..7320)
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018907611.1"
                     /locus_tag="IGA62_RS03605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_07340"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_145816254.1"
                     /transl_table=11
                     /translation="MVGTPLRWDDYATAWARLHGGFDPRTAAPVVRGWLRFAYHVGYLL
                     GRLRVTPTAVTAAGVLLCFCVPLFAVRPSDGPFLAALFVLLASVADSVDGAVAVVTGRN
                     TRLGYVYDSLADRLGEVAWLLAFWLMGAPGALVVAGGALSWLHEYVRARAVAAGMREIG
                     AVTVGERPTRVSVALVGLLVAGLTGLVRPELAAGTITLATAVWVLLAGFGLGQLLSAVR
                     RALLAADAPGPAHVR"
     gene            complement(7401..8318)
                     /gene="metF"
                     /locus_tag="IGA62_RS03610"
                     /old_locus_tag="GCM10017556_07350"
     CDS             complement(7401..8318)
                     /EC_number="1.5.1.20"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785290.1"
                     /locus_tag="IGA62_RS03610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_07350"
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_145816253.1"
                     /transl_table=11
                     /translation="MALGLPSVLPSSQPSIGELIRDCQPTFSFEFFPPKTPAGETLLWQ
                     AIRELESLRPSFVSITYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHV
                     IGRLAGVGVRNVLAVRGDPPGDPTGEWVPHPEGVHYAEDLVRLIRDSGDFSVGVAAFPY
                     RHPRSPDVASDTDYFVRKCRAGADFAITQMFFDADDYLRLRDRVAAAGCDTPILPGVMP
                     VTQLATIARSEQLSGAPFPPALAERFAKVGDDPEAVRRLGIEQASEMCRRLLDEGVPGI
                     HFITLNRSTATREVWRNLQVGARV"
     gene            8631..10004
                     /locus_tag="IGA62_RS03615"
                     /old_locus_tag="GCM10017556_07360"
     CDS             8631..10004
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287635.1"
                     /locus_tag="IGA62_RS03615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_07360"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_145816252.1"
                     /transl_table=11
                     /translation="MIPPPSPGPELFGPLLARLRLARGWSQAQLAARLCAAAGVATLSR
                     HEVSRWERQVRVPGEFWLGWLAVVLAVPRVRLSEAAVASRRTDAYPVTDGSRERRALLA
                     LAQRWLADPEGSLPPPGLTGSRGDPTWSWDDPTGSRDQPARSWDDPAGWLDRLRRLDDL
                     SGGTDLAGLSASRLRWVARAVRLAGPSGRRRLLPVLGEAAQLAGWLAADAGDPAGGLAA
                     YRLGLRAAAAAGDRALAGHVLGSASHLLAGIGDPPGALLLARVAYTGAGPGAPAGLRAV
                     LSHRTAVAAALDGRHATAGQALTVARRAADRHDPRREPPWLYWLDPAELAAMTGRTLAV
                     LGRPLRAEPLLRAGCRSGQPRATAIYGGWLARVYLDLGEVEQACAVAGEALLATVRAGS
                     ARAAGHLTEVGRRLAAYRAEPAVRRHAALVTAARPYLPRRVTPPVVRGRRRRPASVVT"
     gene            10001..11083
                     /locus_tag="IGA62_RS03620"
                     /old_locus_tag="GCM10017556_07370"
     CDS             10001..11083
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072192.1"
                     /locus_tag="IGA62_RS03620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_07370"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_145816251.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.2e-48, bitscore:
                     162.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHAAPVSPVDRAGLRQRVDKALTGFLTTQRGWLTGVDEALVPVA
                     EAVEAFVLRGGKRLRPAFGYWGYRGAGGVDSDQVVATLAALEFVQASALIHDDLMDRSD
                     TRRGEPAVHRRFASRHRASGWTGDAEGFGDAAAILLGDLCLVWSDEMLHSAGLDARTLA
                     RARPVFDEMRTEVTVGQYLDVLTQATGDTSLERAGKVARYKSAKYTVERPLLLGAALAG
                     ATAEVEATYSAYGLPLGEAFQLRDDVLGVFGDPAQTGKPAGDDLREGKRTYLVAAAVAG
                     TDDAGRALIDRHLGDPGLDGAGVARLREVITASGALARTEERIAALTDTALAALATVDL
                     ETEARQALVDLAIAATRRAD"
     gene            complement(11094..11453)
                     /locus_tag="IGA62_RS03625"
                     /old_locus_tag="GCM10017556_07380"
     CDS             complement(11094..11453)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl_fung"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015620028.1"
                     /locus_tag="IGA62_RS03625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_07380"
                     /product="lycopene cyclase domain-containing protein"
                     /protein_id="WP_145816250.1"
                     /sec_met_domain="Lycopene_cycl_fung (E-value: 3.1e-15,
                     bitscore: 54.8, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYTVAALLGAAGAAVIDLYVLRTRLLLRPVFWATYPIIVFFQLV
                     SNGILTGRNIVRYDPGAIIGVRLAYAPVEDLVFGFALVLLTLSVWIWLGRRGVQRTPTA
                     GEGSRLLRLLGRPRP"
     gene            complement(11450..11869)
                     /locus_tag="IGA62_RS03630"
                     /old_locus_tag="GCM10017556_07390"
     CDS             complement(11450..11869)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl_fung"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF039186.4"
                     /locus_tag="IGA62_RS03630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_07390"
                     /product="lycopene cyclase domain-containing protein"
                     /protein_id="WP_145816249.1"
                     /sec_met_domain="Lycopene_cycl_fung (E-value: 4.5e-19,
                     bitscore: 67.1, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRQFVYLGVLAGCLLCALWLEPVFRVNVLRRWRRLLLTLVPVVLV
                     FALWDLAAIAAGHWTFDPEQTTGVLLPGDLPLDELLFFVVVPVCAILGFEAVRAVNRWP
                     AGDEPAGPPVGPAAASPDGARSPSGPVTPGTGDRA"
     gene            complement(11872..12252)
                     /locus_tag="IGA62_RS03635"
                     /old_locus_tag="GCM10017556_07400"
     CDS             complement(11872..12252)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016816979.1"
                     /locus_tag="IGA62_RS03635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_07400"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_145816248.1"
                     /transl_table=11
                     /translation="MSESVPADRAVPGPGPAADDAWLNLPDVAERLDVSISKVHQMIRD
                     RELVAVRRDGIRKIPVDLVANQTVLKHLPGVLNLLADAGYDDDAALRWLYEPDDTLPGT
                     PAVALGGDLAREVKRRAQALGF"
     misc_feature    12360..12378
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.03"
                     /tool="antismash"
     gene            12385..14391
                     /gene="pknB"
                     /locus_tag="IGA62_RS03640"
                     /old_locus_tag="GCM10017556_07410"
     CDS             12385..14391
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018730699.1"
                     /locus_tag="IGA62_RS03640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_07410"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_145816247.1"
                     /sec_met_domain="Pkinase (E-value: 6.8e-48, bitscore:
                     161.7, seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 1.3e-06, bitscore: 26.9,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTQVADTLLGSLIEGRYRIRGRVARGGMATVYTATDERLERTVA
                     VKIIHPTQAPDPRSPLAGFVERFTDEAKTIARLTHPNVVAVYDQGTHQGLPYLVMEYVR
                     GRTLRDVLAERRRLNPDEALAITEQMLAAIGAAHRAGLVHRDVKPENVLVAEAPTGGAA
                     NLVDSVVKVADFGLARAVEASGSEEQGNQLMATVAYVAPELVTDGHADPRTDVYSAGVV
                     LFEMLTGRVPYDGDRPVDVAWQHVDRDVPAPSTLVPGLPKVLDELVTRATRREPGARPT
                     DAGAFLAEVQMAREDLGSNAHTAVLRRITDDVVPAVAQPTMAVAPIRPTERPAWARLPE
                     TKTGRRSRNTGAADRPHRRRAAPQGDNPWARLRRQLAAAPPGRLPLIAAVVVVALLLTG
                     AGWWFGFGRYTTTPELVSLTKAQAESQASRAGLSLTYAKPRYDAKVPRDSVLAQDPASA
                     DRIIRGGTITLTLSLGPDHLPVPDVVGKEYELAEADLRHLGLEVVKGKAQYDDNLPAGV
                     VLDTNPKPGTEVNVGTKVTVVLSRGRAPITVPNLVGKSVTDARGALQQLGLVPVETYRD
                     SDRPKDEVIGQSPADGSSVEKGAEVKLEVSKGPAPVVVPRVVDMPCPQGKQVLESQGFP
                     VVVQFNPNGVVRFQNPGENSQVAPGTPVTIGCF"
     gene            14392..15258
                     /locus_tag="IGA62_RS03645"
                     /old_locus_tag="GCM10017556_07420"
     CDS             14392..15258
                     /EC_number="3.1.21.2"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0008833 - deoxyribonuclease IV
                     (phage-T4-induced) activity [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018223226.1"
                     /locus_tag="IGA62_RS03645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_07420"
                     /product="deoxyribonuclease IV"
                     /protein_id="WP_145816246.1"
                     /transl_table=11
                     /translation="MASCADRPVGSHTPTSGGLAKAALPYADATGSEVVQVYVSNSRGW
                     ALPPGDPVQDALFRDGCAARDIPVFIHASLLVNLGSPTPATVARSMETLDHALRRGGAI
                     GARGVVFHAGSSVDPAHDAAAMRQVRESLLPLLDAAAAAGGPMLLVEPSAGGGRSLASR
                     VEQLGPYLDAVDRHPWLGVCFDTCHAWAAGHDLAAEGGMSATLDTLVATIGTDRLRLVH
                     ANDSKDLCGSTRDRHENIGKGTIGEPAFAELMAHPATAGVPVVVETPTEKHVGHAADIA
                     TLRRLRP"
     gene            complement(15416..16435)
                     /locus_tag="IGA62_RS03650"
                     /old_locus_tag="GCM10017556_07430"
     CDS             complement(15416..16435)
                     /NRPS_PKS="Domain: Beta_elim_lyase (2-271). E-value:
                     1.6e-82. Score: 269.0. Matches aSDomain:
                     nrpspksdomains_IGA62_RS03650_Beta_elim_lyase.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072196.1"
                     /locus_tag="IGA62_RS03650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_07430"
                     /product="GntG family PLP-dependent aldolase"
                     /protein_id="WP_145821821.1"
                     /transl_table=11
                     /translation="MVDLRSDTVTRPTAGMREAMATAEVGDDVYGEDPTVNALEAEVAA
                     LFGHEAALLAPTGSMANQIALQLVVPPAHELLCDADAHVVTYEIGAAAAYGGISSRTWP
                     AVGGDVAPDVVAAMVRPDGYWAVPTRAIAVEQTHNRGGGGVIPLTTLHALRRIADDAGV
                     ALHCDGARIWHAHVAEGVPLAEYGALFDTLSVCLSKGLGAPVGSLVIGSAEHIERARYV
                     RKRLGGGMRQAGVLAAAGRYALAHHVSRLAEDHAKAARLAEAIAPFGLLATTVRTNIVP
                     LDLTKASLDAHALAAAARAEGVLVSVLGPRTARLVTHLDVDDAGIDRAVAVLTRILSR"
     aSDomain        complement(15623..16429)
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IGA62_RS03650_Beta_elim_lyase.1"
                     /evalue="1.60E-82"
                     /label="IGA62_RS03650_Beta_elim_lyase.1"
                     /locus_tag="IGA62_RS03650"
                     /protein_end="271"
                     /protein_start="2"
                     /score="269.0"
                     /tool="antismash"
                     /translation="DLRSDTVTRPTAGMREAMATAEVGDDVYGEDPTVNALEAEVAALF
                     GHEAALLAPTGSMANQIALQLVVPPAHELLCDADAHVVTYEIGAAAAYGGISSRTWPAV
                     GGDVAPDVVAAMVRPDGYWAVPTRAIAVEQTHNRGGGGVIPLTTLHALRRIADDAGVAL
                     HCDGARIWHAHVAEGVPLAEYGALFDTLSVCLSKGLGAPVGSLVIGSAEHIERARYVRK
                     RLGGGMRQAGVLAAAGRYALAHHVSRLAEDHAKAARLAEAIAPFGLL"
     gene            complement(16583..17989)
                     /locus_tag="IGA62_RS03655"
                     /old_locus_tag="GCM10017556_07440"
     CDS             complement(16583..17989)
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475760.1"
                     /locus_tag="IGA62_RS03655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_07440"
                     /product="class II 3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="WP_091459825.1"
                     /transl_table=11
                     /translation="MRHEWHQLSYPAVGGPGLQTSRPTADSAEDAALGLDHWRSLPRAQ
                     TPPWPDPAAVAEVCTVLDTVPSVVAPYEVDQLRHRLALVCEGQAFLLQGGDCAETFADN
                     TESHLLANARTLLQMAIVLTYGASLPVVKVARAAGQYTKPRSLPTDARGLPAYRGDMIN
                     SLEATPEARVADPQRMIRAYANSAAAMNMLRAYLAGGLADLHAVHDWNKGFVRNSPAGE
                     RYEAIAREIDRALAFIRACGMTDEEALRTVTLYCSHEALALEYDRALTRVSDSRAYGLS
                     GHFLWIGERTRQIDGAHVDFISRIANPIGVKLGPTTSPDEALELCEKLNPENVPGRLTL
                     ISRMGNHKVRDALPPIVAKVAAAGAKVVWQCDPMHGNTHESSNGYKTRHFDRIVDEVLG
                     YFEVHRNLGTHPGGLHVELTGEDVTECLGGAQNIADLDLPGRYETACDPRLNTQQSLEL
                     AFLVAEMLRG"
     gene            complement(18118..18630)
                     /locus_tag="IGA62_RS03660"
                     /old_locus_tag="GCM10017556_07450"
     CDS             complement(18118..18630)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018223223.1"
                     /locus_tag="IGA62_RS03660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_07450"
                     /product="hypothetical protein"
                     /protein_id="WP_145816245.1"
                     /transl_table=11
                     /translation="MAVKRGTVSLAVVLAALTFALPGCGIGDDEPAEEPDRAPAEEAAT
                     RSRERVQAYLDAMVAKDVAAGRSQFCATAHAAFDAAATSPNGDFAAHFTVPEATVTDVR
                     PGSRGQEVSTSVTVSVGGRSTTRALLFTVTRSGADWCIAEEAPGDPSAPGSPSEGASPA
                     PTPTAAP"
     gene            complement(19112..20719)
                     /locus_tag="IGA62_RS03665"
                     /old_locus_tag="GCM10017556_07460"
     CDS             complement(19112..20719)
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018807938.1"
                     /locus_tag="IGA62_RS03665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_07460"
                     /product="glycosyl hydrolase family 18 protein"
                     /protein_id="WP_190289252.1"
                     /transl_table=11
                     /translation="MRRSLRRALWASAVVAVTVAAVPMTSAFGAGSVTTTFTKVQDWGT
                     GHETRVTITNGSDAPVSTWRIEFDLPSGTSISSSWDADVTRSGDHYVAVKKSWAGGIAP
                     GGAFSWGYNGTGAYRAPLNCTVNGAPCGGGTTPPTTTPPTTAPPTTPPPTTPPPTTPPP
                     TGDKKVVGYFAQWGVYARNYHVKNIHTSGSAAKMTHIMYAFGNTTGGRCTIGDSYADYE
                     KAYTAADSVDGVADTWDQPLRGSFNQLRKLKKMYPHLKVIWSFGGWTWSGGFTQAAQNP
                     AAFAESCYNLVEDPRWADVFDGIDIDWEYPNACGLTCDASGPNAYKNVISALRSKFGSS
                     ALVTSAITADGSNGGKIDATDYAGAASNLNWFMVMTYDYFGAFNAQGPTAPHSPLYSYT
                     GIPQQGFNSDAAIQKLKSKGIPSNKLLLGIGFYGRGWTGVTQTTPGGTATGPAPGTYEQ
                     GIEDYKVLKNSCPATSTIAGTAYAKCGSNWWSYDTPATIGGKMTYAKNQGLGGAFFWEL
                     SGDTSNGELVGAIKGGLG"
     misc_feature    complement(20732..20749)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.77"
                     /tool="antismash"
     misc_feature    20746..20760
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.01"
                     /tool="antismash"
     gene            20963..21457
                     /locus_tag="IGA62_RS03670"
                     /old_locus_tag="GCM10017556_07470"
     CDS             20963..21457
                     /EC_number="1.11.1.-"
                     /GO_function="GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475757.1"
                     /locus_tag="IGA62_RS03670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017556_07470"
                     /product="glutathione peroxidase"
                     /protein_id="WP_145816244.1"
                     /transl_table=11
                     /translation="MSVFDIGINALAGGPANLSDHRGRALLVVNVASQCGLTPQYAGLQ
                     KLYDAYAGRGLVVLGVPCNQFAGQEPGTADEIGEFCRISYGVSFPLTEKVEVNGPGRHP
                     LYALLTQATDADGHTGDVRWNFEKFLVAPDGTVAARFAPTVEPDAPELHAAIQRVLPAT
                     T"
     misc_feature    complement(21568..21583)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.02"
                     /tool="antismash"
     misc_feature    complement(21830..21844)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.84"
                     /tool="antismash"
ORIGIN
        1 gggagcagcg ccgcgaaaca cccctcccgg gtagtgggaa ccggtgcccg actcaatcga
       61 acacccgttc taaccactgc tgacagtaca ccctgccgcc ggggaaaacg caacgtgtga
      121 cacgacgcga cctcgccgga tctcgcctgc gggcaccccc tccgacctcg gtagcctcgc
      181 agcgtgcgca caccccgtcc cgccctcggc gtcgtcatgg tgctctgctc gggcgtcctc
      241 ttcgccgtca acggcaccgt ctccaagctg gtgctccgca ccggcatcga cgcaccgcag
      301 ctcaccctgc tccgcgcggc cggcgcgttc accgtcctgc tggcgctgag cgcgctgctc
      361 cgccccggca tccggcggct acgggtcacc gccgggcagg tcccgctgct ggtcgggtac
      421 ggactgaccg gcttcttcct ggtgccgatg ctctacttcg tcgccatctc ccgactgccg
      481 gtcggcatcg ggctgctctt cgagtactcc gccccgctgc tggtcgccct ctgggcccgg
      541 ttcgggcagc ggcacccggt ccgaccccgg ctctgggccg gcctggcgct gagcctggtc
      601 gggctggcct gcgtggcgga gatctggggt gagttcacgc tcgacggcct cggggtgctg
      661 gccggtctcg gagccgcgtt cttcctcgcc ttctactacg tgctcggtgc gcggggcgtc
      721 gagggacggg acacggtctc gctctgcacc tgggcgttcg gcgcggccgc cgtggccggc
      781 ctgctcaccc gggcggtcac cggcgtcggc gactggaccc cgctggccgg caccagccgg
      841 ggcgtcccgg tcgtgctgct gctcgggtac gtggtcgtgc tcggctcggt ggtgccgtac
      901 ctgctggtgg ccggggcgat gcgacacctc ccggcgacca gcgtcgggat cgtcgggatg
      961 gtcgagccgg tgatcgcctc ggcggtcgcc tgggtgaccc tcggcgcgac cgaggcactc
     1021 aacgccgccc agctcggcgg gggcctgctg gtgctggtcg gggtcgcgct ggccgagacg
     1081 gcccgggtcg ccccgggccg gacgcccccg tcggcggaga ccgaccggcc cggcccgccg
     1141 gacgtggtcg ccgtggtcac caccggtccg gccgaacccg ggcgccgcac ctgagcgcgg
     1201 acggaaccct cacccccggc ctggcgtggc cggcgcgacg ggcggcggcg taccggggag
     1261 aatggccagc atgcagccac accccaccgt gcgggcggtg caggacgcgc gcgacgccac
     1321 gacggcgcgc gacggttccg gcgggctcgc cccactcggg catcccgccc tgccgcggat
     1381 gaccgccggc atcccggccg gggtggcgtg agcgagcgcc ccggccgggg tggcgtgagc
     1441 gagcgccccg gccgggatgg cgcgagcggg ccgccctccg gctcctcagg ccagcccacg
     1501 gggtcgtcct ccggcccgga gcccgtcggc gggctggtca ccctgcacgt ctggcgggtg
     1561 ggtcggagcg acctgccccg ggtgctgccc cggatggcgt tcggcccgcg ctggctgcgc
     1621 gccaccgacg gggtgcgctt cgccaagctg ctcggcaccg gaacgggcac cgggttcggc
     1681 cccggcgacg tcgacccgac ccgctgggcc gcgctgaccg tctggacgtc ggccgaggcg
     1741 gcggccggct tcgacgactc cccggtcggc cgctcctggg cccggctcgc ccgcgcgacc
     1801 gtccggctcg acctacgtcc ggtggccagc cggggtgagt ggtcccgccg acggccgttc
     1861 ggcgatccgg ccggcgggcg ggtgaccggg cgggtgaccg ggccggtgct ggcgctgacc
     1921 cgcgcccggc tgcgcccccg gcgggcgctc accttctggc gggccgtccc cccggtggcc
     1981 gccgcgctgc accacgcgcc cggcctgctc gcccggttcg gcgtcggcga ggccccgctg
     2041 ggctggcagg gcacggtcag cctgtggcgt gatccggcga gcctggtcga gttcgcgtac
     2101 cgtcacccgg agcaccgggc cgcgatcgcc cgcaccccca ccgagggctg gtacgcggag
     2161 gaactgttcg cccggttcga ggtgcgtgcc gtgaccggtg accgggcggt gctgggctgg
     2221 accggtgacg acgacacgga gacggtggag ggcgggcacg catgaggttg gtgcggtgga
     2281 ccccggacga tctcgtccgg cggctggacg acgtggtcgc cgtctacggc gaggcgatgg
     2341 ggtaccggcc ggacctgctg gagtcccggc gcggctacat cgccacccac gtccgccggc
     2401 cgggcttccg cgcggtggcc agcctcacca gcgagggcca cctggccggc ttcgggtacg
     2461 gctacctcgg cacacccggg cagtggtggc acgaccaggt cagtcgggcg ctggacccga
     2521 cccggcgcgg gatctggctg acccactgct tcgaggtcgt cgagctgcac gtccggcctt
     2581 cggcgcaggg gcacggcctc ggcgcggggc agctgcgggt gctgctgacc atggccgagg
     2641 ggagcaccac gctgctgtcc accccggagg ccgacgagga acgctcccgt gcctggcggc
     2701 tctaccgccg gttcggcttc gtcgacgtcc tgcggaactt ccacttcccc ggcgacgaac
     2761 gcgcgttcgg cgtgctcggc cggaccctcc cgctgccgcc gccggcgccc tccggcccca
     2821 cggcgtccgc cgggccggcc gtctccggcc cgtacccgtc gtgagcggtg accgggccgc
     2881 atccgccgtg gccggcggcg accggtccgc cgacggaccc cggcccggac ggggcgtcga
     2941 cggggacgcc cggccacccc ggctgagctg ggtactgctc ggcgtcctcg tcctcgccca
     3001 gatcggctac ccgctgaccg gcgggggcac ccgggcggcg ttgaccgtgg ccacggtcgt
     3061 gctcggctac ctcctctcgg tcggccacgc gctgctcacc cgggggcccc ggacggcggc
     3121 ggcgctggtc gcggtcgcca ccggcggcgg gttcgccatc gaggcgctcg gcgtggccac
     3181 cggtttcccg ttcggcagct acgactactc cggtcaactc ggcccgaagc tcgccggggt
     3241 gcccctgatc atcccgctgg cctggacctg gatggcctgg ccggcgtggc tcgccgcggt
     3301 ccggctggtc cgccccggcg tacggcgggt cgcgctggcc gccgtcggcc tggccacctg
     3361 ggacctcttc ctcgacccgc agatggtcgc cgaggggtac tggcgctggc gggacgccac
     3421 cccggcgctg cccggactgc ccggcgtccc ggtcagcaac tacctcggct ggctgctgtt
     3481 cggggtgctg atgatgacgc tgctgcgccc gctggccgga gcatcggccg accggaccgg
     3541 ccctgcggac cacccgatgt acgcgctgta cctgtggacg tacttctcca gcgtgctggc
     3601 ccacgcggtc ttcctcgggc tgcccgcctc ggcgctctgg ggcgcggccg gcatggcggt
     3661 cgcggcggtg ccactggcgg tgacgctcgc ccggggccac cggcggcgtc caccggccgg
     3721 cacggggaac gggtccggcc agcggcgggt ggacgccacc gcatgaccgg tccggtcgtc
     3781 gccgtgctgg tcccgctggc cgtgctcgcc gcgctgaccg ggcacaccct ggtcaacgcc
     3841 acccgctggc tgcgccgacc ggccgaccgg cccgccgagg tcgacgaacc ggtggcggtg
     3901 ctgctgccgc tgcgcgacga ggccgcccgg gtcaccccgt gcctgcgggc gctgctcgcc
     3961 cagcggggtg taccggagat gcggatcgtg gtacttgacg acggctcgac cgacggcacc
     4021 gccgaggtgg tgcgcgccgt ggtcgacggc gacccccggg tcaccctgct ggccggggtg
     4081 cccccgccac cgggctggct gggcaagccg cacgcctgcc accagctcgc gcagcgggcc
     4141 gacccggcag ccaccgcgct ggtcttcgtc gacgccgacg tcgtcctcgc cccggacgcg
     4201 gtggcggcgg ccgtcgccga gctacgcgcc gcgcgggtga cgctgctgtc gccgtacccg
     4261 aggatcctgg tgacgacggt gggcgaccgg ctggtccagc cgctgttgca gtggctgtgg
     4321 ctgaccttcc tgccgctacg cgcgatggaa cgctcggccc ggccctcgct ggcggcggcg
     4381 ggcgggcagt tcctggtggt ggaccgggcc ggctaccgcg ccgccggcgg gcacgcggcc
     4441 gtccgggacc gggtgctgga ggacatcgag ctggcccgcg cggtcaagcg ggccggcggc
     4501 cggatcgccc tggccgacgg ctcccggctg gccgactgcc ggatgtacga cacctggccg
     4561 cagctgcgcg acggctacac caagtcgctc tgggcctcgt tcggtcaccc gggcgcggcg
     4621 gcggccgtgg tggccctgct cggcctgctc tacgtggcgc caccgctgct ggtcggggcc
     4681 gcactgctgg tcggcgcgcc gacggtcgcc acgctggcgg ggaccggcta cctgctcggt
     4741 gtcgcgggtc gggtggtcag cgcccgggcg accgggggcc ggtggtggcc cgacgcgctc
     4801 gcccaccccg tatcggtcgt ggtcctcggt tggctgacca tccggtcgta ccatctgcgg
     4861 aagcgacgcc gcctctcctg gcgcggtcgc ccggtcggct aggagggcgc gacacatggc
     4921 tcgggttgtg gtcgtcggtg ccggggtggg tgggctcgcc accgccgccc ggctggccgc
     4981 cgcgggacac gaggtaaccg tcttcgagca ggccgacacg gtcggcggga agctcggccg
     5041 gtacacgcac gacacacccg ccgggtcgtt ccacttcgac accggcccga gtctgctcac
     5101 cctccccgag gtcttcaccg agttgttcga ggcgaccggg gcgaagctcg acgagtacct
     5161 ggacctcgtc ccgttggacc cgatcgtgcg gcacgtcttc ccggacggca cgacccccgg
     5221 cgggggcacg accctggact cctgcgccga cccggtggag ttcaccgagc ggatcggcgc
     5281 ggcgttcggg gagcggtcgg cggccgactg gcgggggctg tggcgccgcg ccggccgggt
     5341 ctgggagacg tcctggcagc acgtcctgcg ccggccggtc gactcccccc gggacctggc
     5401 cgcgctggcc tggcggctcg gcgacctggc cgcgatcgca cccggccgga ccctgcgcgg
     5461 gctgggccgc cgccacctga gcgacccccg gatgcggatg ctgctcgacc ggtacgccac
     5521 ctacaccggc gcggacccgc gtcgcgcccc ggccgcgctg gtcgccgtcc cctacgccga
     5581 gctggccttc ggcggctggt acctgcgcgg cgggctgggc acgctcgccg acgcgctgct
     5641 gtcgcgctgc ctggacctcg gcgtggtcgt gcagaccggc accgcggtca cccggatcga
     5701 cgcggccggc gggcgggtcc acggggtacg cctgcgcggc atcgccgcac cggtccccgc
     5761 cgacgtggtg gtggccaacg tcgacgcgct gaccgtctac cgggacctgc tgcccagccc
     5821 cggccggctc gccgggctcg ccgaccgcag cctcgccggg ttcgtgctgc tgctcggggt
     5881 acgcgggccg accggcctgg cacaccacaa cgtgttcttc ccccgcgact acgacgccga
     5941 gttcgacgcg gtcttcggcg acccggggcg gggtgtccgc gcccggcccg cggtcgaccc
     6001 gacggtcttc gtcaccgtgg ccgacgacgc ggtggtccgc cccgccgacc acgaggcgtg
     6061 gttcgtgctg gtcaacgcgg cccggcacgg caccgccacg tccgccgtcg actggcgtcg
     6121 cccggggctc gccgaggcgt acgcggaccg gatcctggac gtgctcgccg agcggggcat
     6181 cgacgtgcgg gaccggttgc tgttccgcga gatccgtacc cccgccgacc tgggcagcgc
     6241 caccggcgcg ccgggcggcg cgatctacgg cactgccggc gggctgctgc gtccggccaa
     6301 ccgcgccccg gcgtacggcg tgcacctggt cggcggctcc acccacccgg gcggcggcct
     6361 gcccatggtg accctctccg cccgcatcgt cgccgaccgg atcggcccgg cctgactcac
     6421 cgccacccct gcccggtggt agggcggcca cccctgcccg gtggtagcag gggtcccctg
     6481 ctaccgcttt ttgtcgagga agggccccct gcaaccacgc cacgacacac cacgccacgc
     6541 caccccaacc acccaccacc cctaccaccg gcaccggcac cggcaccggt gccagacagg
     6601 gcggcgtcag cggacgtggg ccggaccggg ggcgtcggcg gcgagcaggg cgcgacggac
     6661 ggcggagagg agctgcccca gcccgaaacc ggcgagcagc acccagacgg ccgtcgccag
     6721 ggtgatcgtg ccggcggcca actcgggccg gaccagcccg gtcagcccgg ccaccagcag
     6781 cccgaccagc gcgacactga cccgggtcgg ccgctccccc accgtcaccg cgccgatctc
     6841 gcgcatgccg gcggcgacgg cgcgggcgcg tacgtactcg tgcagccagg agagcgcgcc
     6901 tccggccacc accagtgctc ccggcgcccc catcagccag aacgccagca accaggcgac
     6961 ctcaccgagc cggtcggcca gcgagtcgta gacgtagccg aggcgggtgt tacgaccggt
     7021 caccaccgcc accgcgccgt ccacgctgtc ggccaccgag gcgagcagga cgaagagcgc
     7081 ggccaggaac gggccgtcgg aggggcgtac ggcgaacagc ggcacgcaga agcagagcag
     7141 caccccggcg gcggtgaccg ccgtcggggt gacccgcaac cggcccagca ggtagccgac
     7201 gtggtacgcg aaacgcagcc agccgcggac caccggggcg gccgtccggg gatcgaagcc
     7261 cccgtgcaac cgggcccagg cggtcgcgta gtcgtcccat ctcagcggag tgcccaccac
     7321 ggatcaaccg taggagggct cgtcgggtgt cgcggtcggc ggtacccggt cgtggtccgc
     7381 gccgggacac ccggtgccgc tcacacccgc gcgccgacct ggaggttccg ccagacctcc
     7441 cgggtggcgg tggagcggtt cagggtgatg aagtggatgc ccggcacgcc ctcgtcgagc
     7501 agccgccggc acatctcact ggcctgctcg atgccgagcc gacggaccgc ctccgggtcg
     7561 tcgccgacct tggcgaaccg ttcggcgagc gcgggcggga agggtgcccc ggagagctgc
     7621 tcggaacggg cgatggtggc gagctgggtc accggcatca ccccgggcag gatcggggtg
     7681 tcgcagccgg cggcggccac ccggtcacgc aggcggaggt agtcgtcggc gtcgaagaac
     7741 atctgggtga tcgcgaagtc ggctcccgcc cggcacttgc ggacgaagta gtcggtgtcg
     7801 gaggcgacgt ccggcgagcg ggggtggcgg tacgggaagg cggcgacccc gacgctgaag
     7861 tcaccggagt cacggatcag ccgcaccagg tcctcggcgt agtgcacccc ctcggggtgc
     7921 gggacccact ccccggtggg gtctccgggc gggtcgcccc ggaccgccag cacgttgcgc
     7981 acgcccaccc cggccagtcg cccgatcacg tgccgcagtt cggcgacgga gtggttgacg
     8041 gcggtgaggt gcgccatcgg cagcagggtg gtctcggtgg cgatccgttc ggtgaccgcc
     8101 acggtggtgt cccgcgtcga gccgccggcg ccgtaggtga tcgagacgaa cgagggacgc
     8161 agcgactcca gctcgcggat cgcctgccag agcagggttt cgccggccgg ggtcttgggc
     8221 gggaagaact cgaacgagaa ggtcggctga cagtcgcgga tcagttcccc gatcgacggc
     8281 tgggagctgg gaaggaccga gggaagaccg agcgccactc catgactcta ccgggcgggg
     8341 gcatctgcgg gcggcccccc gatgggcggt ccggtcgagg cacgccggac ccccggtcga
     8401 ggcacgccgg accctgggtg gcggccgtcg gatgggtggc ggccgtcgga tgggtggcgg
     8461 cggtcccgcc gcggcggatt cgtcgtaccc ctcgggtagg cagtggggca gcacggtgag
     8521 ccgatggggg tcggtcgcca gccgtgcggg ggtccacagt ctgaatcgac ggcgcaccgg
     8581 tccgggccac ccggccgccg gggccgccgc gccgacctcc cggaggcccc atgatcccgc
     8641 ccccgtcgcc cggcccggag ctgttcgggc ccctgctcgc ccggctccgg ctggcccggg
     8701 gctggagcca ggcccagctc gccgcccggc tctgcgccgc cgccggagtc gccacgctca
     8761 gccggcacga ggtctcccgc tgggaacggc aggtgcgcgt gcccggggag ttctggctcg
     8821 gctggctcgc cgtcgtgctg gcggtccccc gggtacggct gtccgaggcc gcagtggcga
     8881 gccgccgcac cgacgcgtac ccggtgaccg acgggtcccg ggagcgacgg gcgctgctgg
     8941 ccctggccca gcggtggctg gccgacccgg aggggtcgtt gccgccaccc ggcctgacgg
     9001 gctcgcgggg cgacccaacc tggtcgtggg acgatccgac gggctcacgg gaccagcccg
     9061 cccggtcgtg ggacgacccg gccggctggc tggaccggct gcgccggctc gacgatctgt
     9121 ccggcggcac ggacctggcc gggctgagcg cgtcccggtt gcggtgggtg gcccgcgcgg
     9181 tccggctggc cggcccgtcc gggcggcgcc gactgctgcc ggtgctgggc gaggcggcgc
     9241 agctcgccgg gtggctcgcc gccgacgccg gtgacccggc cggtgggctg gccgcgtacc
     9301 gactggggtt gcgggccgcc gcggcggccg gtgaccgggc gctggccggg cacgtgctcg
     9361 gctcggcgag ccacctgctc gccgggatcg gtgacccgcc cggcgcgctg ctgctggccc
     9421 gcgtcgcgta caccggggcc ggtccgggcg ccccggccgg gctgcgggcg gtgctgtcgc
     9481 accggacggc ggtggccgcc gcgctcgacg gccggcacgc cacggccggg caggcgctca
     9541 ccgtcgcccg gcgcgccgcc gaccggcacg acccgcgccg ggagccgccc tggctctact
     9601 ggctcgaccc ggcggaactg gccgcgatga ccggccggac gctggccgtg ctgggccgac
     9661 cgctgcgcgc cgaaccgctc ctgcgcgccg gctgccgctc cggacagccg cgcgccacgg
     9721 cgatctacgg gggctggttg gcccgcgtct acctcgatct cggcgaggtc gagcaggcct
     9781 gcgcggtggc cggagaggcc ctgctcgcca ccgtccgggc cggatccgcc cgggcggccg
     9841 gtcacctcac cgaggtgggg cgccggctcg ccgcgtaccg ggccgaaccg gccgtacgcc
     9901 ggcatgccgc gctggtcacg gctgcccgtc cgtaccttcc ccggcgcgtc acacccccgg
     9961 tggtgcgcgg tcgtcgacgg cgaccggcta gcgtcgtgac gtgacccacg cagctcccgt
    10021 atcccctgtc gaccgtgccg gcctgcgaca gcgcgtcgac aaggccctga ccggattcct
    10081 gaccacccag cggggttggc tgaccggggt cgacgaggcg ctggtgccgg tcgccgaggc
    10141 ggtcgaggcg ttcgtgctgc ggggcggcaa gcggctgcgg ccggcgttcg gctactgggg
    10201 ctaccggggc gccggagggg tggattccga ccaggtggtc gccaccctcg ccgcgctgga
    10261 gttcgtgcag gccagcgcgc tgatccacga cgacctgatg gaccggtcgg acacccggcg
    10321 gggcgagccg gccgtacacc gacggttcgc ctcccggcac cgcgcctccg ggtggaccgg
    10381 ggacgcggag ggcttcggcg acgccgccgc gatcctcctc ggcgacctct gcctggtgtg
    10441 gtccgacgag atgctgcaca gcgccgggct cgacgcgcgg accctggccc gggcccggcc
    10501 ggtcttcgac gagatgcgca ccgaggtcac cgtcgggcag tacctggacg tgctgaccca
    10561 ggccaccggg gacacctcac tggagcgggc cgggaaggtg gcccgctaca agtcggccaa
    10621 gtacaccgtc gaacggccgc tgctgctcgg tgccgcgctg gccggggcga ccgccgaggt
    10681 cgaggcgacc tactcggcgt acgggctgcc gctgggcgag gcgttccagc tccgcgacga
    10741 cgtgctcggg gtgttcggcg atccggcgca gaccggcaag ccggccggcg acgacctgcg
    10801 cgagggaaag cggacgtacc tggtggcggc ggccgtggcg gggaccgacg acgcgggacg
    10861 ggcgctgatc gaccggcacc tgggcgatcc cggactggac ggggccgggg tggcacgcct
    10921 ccgcgaggtg atcacggcca gcggggcact ggcgcgcacc gaggagcgga tcgccgccct
    10981 caccgacacc gcgctggccg cgctcgccac cgtcgacctg gagaccgagg cccggcaggc
    11041 cctggtcgac ctcgccatcg ccgccacccg tcgcgccgac tgaccctccc cggtcaggga
    11101 cgggggcgac ccaggaggcg gagcaggcgg ctgccctcgc cggcggtcgg ggtgcgctgc
    11161 acgccccggc ggccgagcca gatccacacc gacagggtca gcagcaccag cgcgaagccg
    11221 aagaccaggt cctccaccgg cgcgtacgcc agccggacgc cgatgatcgc cccggggtcg
    11281 taccggacga tgttccggcc ggtcaggatg ccgttggaga cgagctggaa gaacacgatg
    11341 atcgggtagg tggcccagaa gaccggccgc agcagcagcc gggtccgcag cacgtacagg
    11401 tcgatcacgg ccgcgccggc cgcgccgagc agggcggcga cggtgtacgt catgcccggt
    11461 cccccgtccc cggcgtcacc gggccggacg gcgaccgcgc gccgtccggc gacgccgcgg
    11521 ccggtccgac cggcgggccg gcgggttcgt cccccgccgg ccaacggttg accgcgcgta
    11581 ccgcctcgaa gccgaggatc gcgcagaccg gtacgacgac gaagaagagc agttcgtcca
    11641 ggggcaggtc gccggggagg agcactccgg tggtctgctc cgggtcgaag gtccagtgcc
    11701 cggcggcgat cgccgcgagg tcccagagcg cgaagaccag caccaccggc accagggtca
    11761 gcagcagccg acgccagcgg cgcagcacgt tgacccggaa caccggctcc agccagagcg
    11821 cgcagagcag gcagccggcc agcaccccga ggtagacgaa ctgccgcacg gtcagaaccc
    11881 gagcgcctgg gcccggcgtt tgacctcgcg ggccaggtca ccgccgaggg ccacggcggg
    11941 ggtgcccggc agggtgtcgt ccggctcgta cagccagcgc agcgcggcgt cgtcgtcgta
    12001 gccggcgtcg gcgagcaggt tgagcacacc cggcaggtgc ttgagcacgg tctggttggc
    12061 gaccaggtcg acggggatct tccggatgcc gtcccggcgg accgcgacca gttcccggtc
    12121 gcggatcatc tggtggacct tgctgatcga cacgtcgagg cgttcggcga cgtcgggcag
    12181 gttcagccag gcgtcgtcgg cggcgggacc ggggcccgga acggcccggt cggcgggtac
    12241 ggattcactc acccgatcac cctgccacgt cgtgccgtcc accggccaac gggatcgccc
    12301 cgacgggtgc accgaggtga cgatccggca gcactgtggc atcctgttct gccgccgcct
    12361 cctggagaca tagactgccc cccgatggac acacaggtcg ccgacacgtt gctgggctcg
    12421 ctgatcgagg ggcgctaccg cattcgcggt cgcgtggccc gaggcggcat ggcgaccgtg
    12481 tacaccgcca cggacgaacg tctcgagcgc acggtcgctg tcaagatcat tcaccccacc
    12541 caggcgccgg atccccggtc ccccctggcg ggcttcgtcg agcggttcac cgacgaggcc
    12601 aagaccatcg cccggctcac ccaccccaac gtggtcgccg tgtacgacca gggcacccac
    12661 cagggcctgc cctacctggt gatggagtac gtccggggcc ggaccctgcg ggacgtgctg
    12721 gccgagcgtc gccggctcaa cccggacgag gcgctggcca tcaccgagca gatgctcgcc
    12781 gcgatcggcg cggcacaccg ggccggtctg gtgcaccggg acgtgaaacc ggagaacgtg
    12841 ctggtcgccg aggcccccac cggcggcgcg gcgaacctgg tcgacagcgt ggtgaaggtg
    12901 gccgacttcg gcctggcccg cgcggtcgag gcgagcggga gcgaggagca gggcaaccag
    12961 ctgatggcga ccgtcgcgta cgtcgcgccg gagctggtca ccgacggaca cgcggacccg
    13021 cggaccgacg tctactcggc gggtgtcgtg ctgttcgaga tgctcaccgg tcgggtgccg
    13081 tacgacggtg accgcccggt cgacgtcgcc tggcagcacg tggaccggga cgtaccagcc
    13141 ccgtccaccc tggtgccggg gctaccgaag gtgctcgacg aactggtcac ccgggccacc
    13201 cgccgcgagc cgggagcccg tccgacggac gccggggcgt tcctggccga ggtgcagatg
    13261 gcccgggagg acctcggcag caacgcgcac accgccgtgc tgcgccggat caccgacgac
    13321 gtcgtccccg ccgtcgccca gcccaccatg gccgtcgcgc cgatccggcc caccgagcgt
    13381 cccgcctggg cccggctgcc cgagacgaag accggccgcc ggtcgcggaa caccggcgcg
    13441 gcggaccgac cgcaccggcg gcgggccgca ccccaggggg acaacccgtg ggcccggctg
    13501 cgccgacagc tggcggcggc cccgccgggc cggctgccgt tgatcgccgc cgtggtggtg
    13561 gtcgcactgc tcctcaccgg cgccggctgg tggttcggct tcgggcggta cacgaccact
    13621 cccgagctgg tcagcctgac caaggcccag gcggagtcgc aggcgtcccg cgccgggctg
    13681 tccctcacct acgccaagcc gaggtacgac gcgaaggtgc cccgcgacag cgtcctggcg
    13741 caggatccgg cgtcggccga ccgcatcatc aggggcggca cgatcaccct gaccctctcc
    13801 ctcgggccgg atcatctccc ggtgccggac gtggtgggca aggagtacga actcgccgag
    13861 gcggaccttc gccacctggg tctggaggtg gtcaagggca aggcccagta cgacgacaac
    13921 ctgccggccg gggtggtgct ggacaccaac ccgaagccgg gcaccgaggt gaacgtgggc
    13981 accaaggtca ccgtggtgct gagccgggga cgcgccccga tcaccgtccc gaacctggtc
    14041 ggcaagagtg tcaccgacgc ccgcggggcg ctccagcagc tcggcctggt gccggtggag
    14101 acctaccgtg actcggaccg gccgaaggac gaggtgatcg gccagtcgcc cgcggacggc
    14161 tccagcgtgg agaagggcgc cgaggtcaag ctggaggtca gcaaggggcc ggccccggtg
    14221 gtcgtacccc gggtggtgga catgccctgc ccgcagggca agcaggtgct ggagagccag
    14281 ggcttcccgg tggtggtgca gttcaacccc aacggcgtgg tccgcttcca gaacccgggc
    14341 gagaactccc aggtcgcccc gggcaccccg gtcaccatcg ggtgcttcta gatggcctcc
    14401 tgcgccgacc ggcccgtcgg gtcgcacacc cccacctccg gggggctggc gaaggcggcc
    14461 ctgccgtacg ccgacgccac cggctccgag gtggtgcagg tctacgtctc caactcgcgg
    14521 ggctgggcgc tgccacccgg tgacccggtc caggacgccc tcttccgcga cggctgcgcg
    14581 gcccgggaca tcccggtctt catccacgcg tcgctgctgg tcaacctcgg ctcccccacc
    14641 ccggccacgg tggcccgttc gatggagacc ctggaccacg cgctgcggcg cggcggggcg
    14701 atcggcgcgc ggggggtggt gttccacgcc ggcagttcgg tggaccccgc ccacgacgcg
    14761 gccgcgatgc ggcaggtacg cgagtccctg ctgccgctgc tggacgccgc cgcggcggcc
    14821 ggcgggccga tgctgctggt cgagccgagc gccgggggcg gccggtcgct ggcgtcgcgg
    14881 gtggagcagc tcgggccgta cctggacgcg gtggaccggc acccctggct cggggtctgc
    14941 ttcgacacct gtcacgcctg ggcggccggg cacgacctgg ctgccgaggg cggaatgagc
    15001 gcgaccctgg acaccctggt ggcgaccatc gggacggacc ggctgcggtt ggtgcacgcc
    15061 aacgactcga aggacctctg cggctcgacc cgggaccggc acgagaacat cggcaagggc
    15121 accatcggcg agccggcgtt cgccgagctg atggcccatc cggccaccgc cggcgtcccg
    15181 gtggtcgtgg agacccccac cgagaagcac gtcggccacg ccgccgacat cgccaccctc
    15241 cgccgcctgc gtccctgacc gtccagccct cttctcgccc cccgagttct gacagctcaa
    15301 ctacacgaca cgccggcccc attccaccgc agccggccac gagtcgtccg tcgcgtggca
    15361 gttcacgacc cacccgctcg cactgggcag gccggggccg ggcggcgcgc cccggtcagc
    15421 gggacaggat ccgggtcagc acggcgaccg cccggtcgat gccggcgtcg tcgacgtcca
    15481 ggtgggtgac cagacgggcg gtacgcggcc cgagcaccga caccagcacc ccctcggcgc
    15541 gggcggcggc agccagcgcg tgcgcgtcca gcgacgcctt ggtcaggtcc agcggcacga
    15601 tgttggtgcg gaccgtggtg gcgagcagcc cgaacggagc gattgcctcg gccagtcggg
    15661 cggccttcgc gtggtcctcc gccaaccggg acacgtggtg ggccagcgcg taccgcccgg
    15721 cggcggcgag gacgccggcc tgccgcatgc cgccgcccag ccgcttgcgg acgtagcggg
    15781 cccgctcgat gtgctccgcg ctgccgatga ccagcgagcc gaccggcgcg ccgagcccct
    15841 tggagaggca gaccgacagg gtgtcgaaga gcgcgccgta ctccgccagg ggcaccccct
    15901 cggccacgtg cgcgtgccag atccgggcgc cgtcgcagtg cagggccacc ccggcgtcgt
    15961 cggcgatccg acgcagcgcg tgcagggtgg tcagcgggat caccccaccg ccgccccggt
    16021 tgtgggtctg ctccacggcg atcgcccggg tgggcaccgc ccagtagccg tccgggcgga
    16081 ccatcgcggc gaccacgtcc ggggcgacgt ccccaccgac cgccggccag gtccgcgacg
    16141 agataccgcc gtacgccgcc gccgcgccga tctcgtacgt gaccacgtgc gcgtcggcgt
    16201 cgcagagcag ctcgtgggcc gggggcacca ccagttgcag ggcgatctgg ttggccatcg
    16261 acccggtggg ggcgaggagc gccgcctcgt gcccgaagag cgcggcgacc tcggcctcca
    16321 gcgcgttgac ggtcgggtcc tcgccgtaga cgtcgtcgcc gacctcggcg gtggccatcg
    16381 cctcccgcat cccggcagtg ggccgggtga cggtgtccga acgcaggtcg acgatcgtgt
    16441 ccccgctcgc gcccgtcgcc cggtgctcag ccacggtgct cccttcggct accgactgcg
    16501 gggctcgcaa gctcactcct cacgtcagcc accgtgcccc cttccgctgc cgactgcggg
    16561 gctcgcaagc tcactcctca cgtcagccac ggagcatctc cgccaccagg aaggccaact
    16621 ccagcgactg ctgggtgttc agccgagggt cgcaggcggt ctcgtaccgg ccgggcaggt
    16681 cgaggtcggc gatgttctgc gcgccgccga ggcactcggt gacgtcctca ccggtcagct
    16741 cgacgtgcag cccaccgggg tgggtgccca ggttgcggtg cacctcgaag tagccgagca
    16801 cctcgtcgac gatccggtcg aagtgccggg tcttgtagcc gttggaggac tcgtgcgtgt
    16861 tgccgtgcat cgggtcgcac tgccagacca ccttcgcccc ggcggcggcg accttcgcga
    16921 cgatcggcgg cagcgcgtcc cggaccttgt ggttgcccat ccggctgatc agggtgagcc
    16981 ggccggggac gttctccggg ttgagcttct cgcagagttc gagcgcctcg tcggggctgg
    17041 tcgtggggcc gagcttcacg ccgatcgggt tggcgatccg ggagatgaag tcgacgtgcg
    17101 cgccgtcgat ctgccgggtc cgctcgccga tccagaggaa gtgcccggag agcccgtagg
    17161 cccggctgtc ggagacccgg gtcagcgccc ggtcgtactc cagggcgagg gcctcgtggg
    17221 agcagtagag cgtgacggtg cgcagcgcct cctcgtcggt catgccgcag gcccggatga
    17281 aggccagagc ccggtcgatc tcccgggcga tcgcctcgta gcgctcgccg gccggggagt
    17341 tcctgacgaa gcccttgttc cagtcgtgca cggcgtgcag gtcggccagc ccgccggcca
    17401 ggtacgcccg gagcatgttc atcgccgcgg cggagttcgc gtacgcccgg atcatgcgct
    17461 gcgggtcggc gacccgggcc tccggcgtcg cctccagcga gttgatcatg tcgccgcggt
    17521 aggccgggag gccacgcgcg tcggtgggca gggaccgggg cttggtgtac tgcccggcgg
    17581 cccgggcgac cttgaccacc ggcagggacg cgccgtaggt cagcacgatc gccatctgga
    17641 gcagggtgcg ggcgttggcg agcaggtgac tctcggtgtt gtccgcgaag gtctccgcgc
    17701 agtcgccccc ctggagcagg aatgcctgcc cctcgcacac cagcgccagc cggtgacgca
    17761 actggtcgac ctcgtacggg gcgacgaccg aggggacggt gtcgagcacc gtgcagacct
    17821 cggccactgc ggccgggtcg ggccacggcg gggtctgggc gcggggaagg ctccgccagt
    17881 ggtccaggcc gagcgcggcg tcctcggcgg agtccgcggt cgggcggctg gtctggagtc
    17941 cggggccgcc gacggcggga tagctcagct gatgccactc atggcgcatg cccgaaagcc
    18001 tacggcgacg acggcgaccg gtccccgccg agggggcggg ttccgatggt tgggaggcca
    18061 ccggacgacg cgtccaccgg gtcgaggtgg gggcgtcgtc cggtgggact ccgccggtca
    18121 gggcgccgcg gtcggggtgg gggccgggga ggcgccctcc gacgggctgc ccggggcgga
    18181 cgggtcgccc ggggcctcct cggcgatgca ccagtcggcg ccactgcggg tcaccgtgaa
    18241 cagcagcgcg cgggtagtcg accgtccgcc gaccgagacc gtcacggagg tgctcacctc
    18301 ctgcccacgc gatccgggcc gaacgtcggt gacggtcgcc tccgggacgg tgaagtgcgc
    18361 ggcgaagtcg ccgttcgggc tggtcgcagc ggcgtcgaag gccgcgtgtg cggtggcgca
    18421 gaactggctg cgcccggcgg cgacgtcctt ggcgaccatc gcgtcgaggt acgcctgcac
    18481 ccgctcccgg gaccgggtgg cggcctcctc ggcgggggcc cggtccggct cctcggccgg
    18541 ctcgtcgtcc ccgatcccgc acccaggcag ggcgaacgtc agcgcggcca gcacaaccgc
    18601 cagggacacg gtcccccgtt tcaccgccat cggagccccc tcacacgtca cgtcgagccg
    18661 accgagccgc gagtctgtca catcgaccct tctgcatggg gacgtcacca ccggcgcgga
    18721 cgtccggcca cctccgaccg ccgtcggccg gagcgtctga tggaccaacg acgcagcgcc
    18781 cccaccgtcg ccgccataac caccgtcgcc gctataaccg ccaaagccgc cgtaaccgcc
    18841 atagccgcca ccgccgccgt cgcccgttcg cggcctgttg ccctcctcgt ggtagcaggg
    18901 gtcccctgtt accgcttttt gtcgagcagg gggcccctgc aggcacccga cgcggcgggc
    18961 acccgatatg gcaggcaccc gacgcggcgg gcggacgaca cggcaggcac cgacgcggcg
    19021 ggcgggcgac acggcgggca ggtgaacgga cgacgtcggg ggtggggagc ggacgggccg
    19081 ctccccaccc ccgacgggtg gtgcgatcgg gtcagccgag gccgcccttg atggcgccga
    19141 ccagttcacc gttgctggtg tcgccggaga gttcccagaa gaacgcgccg ccgaggccct
    19201 ggttcttcgc gtacgtcatc ttgccgccga tggtggccgg ggtgtcgtag ctccaccagt
    19261 tgctgccgca cttggcgtac gccgtgccgg cgatggtgct ggtcgccggg cagctgttct
    19321 tgagcacctt gtagtcctcg atgccctgct cgtaggtgcc cggggcggga ccggtggcgg
    19381 tgccgcccgg ggtcgtctgg gtgacgcccg tccaaccccg gccgtagaag ccgatgccga
    19441 gcagcagctt gttcgacggg atgcccttgc tcttgagctt ctggatcgcc gcgtcggagt
    19501 tgaagccctg ctgcgggatg ccggtgtacg agtacagcgg cgagtgcggg gcggtcgggc
    19561 cctgggcgtt gaacgcgccg aagtagtcgt aggtcatcac catgaaccag ttgaggttcg
    19621 acgccgcgcc ggcgtagtcg gtggcgtcga tcttgccgcc gttgctgccg tcggcggtga
    19681 tcgcgctggt gaccagtgcc gaggagccga acttcgaccg cagcgcggag atcacgttct
    19741 tgtacgcgtt cgggccgctg gcgtcgcagg tgaggccgca ggcgttcggg tactcccagt
    19801 cgatgtcgat gccgtcgaag acgtccgccc agcgcgggtc ctcgaccagg ttgtagcagc
    19861 tctcggcgaa ggcggccggg ttctgcgcgg cctgggtgaa gccgccggac caggtccacc
    19921 cgccgaagga ccagatcacc ttcaggtgcg ggtacatctt cttcagcttg cggagctggt
    19981 tgaagctgcc gcgcagcggc tggtcccagg tgtccgccac accgtccacg ctgtcggccg
    20041 cggtgtacgc cttctcgtag tcggcgtagc tgtcaccgat cgtgcaccgg cccccggtgg
    20101 tgttgccgaa ggcgtacatg atgtgcgtca tcttggcggc cgagccgctg gtgtggatgt
    20161 tcttgacgtg gtagttccgg gcgtagacgc cccactgggc gaagtagccg acgaccttct
    20221 tgtccccggt cggcggcggc gtggtggggg gcggggtcgt cgggggcggg gtggtcggcg
    20281 gggccgtggt gggcggagtg gtggtcgggg gcgtggtgcc accaccgcag ggcgctccgt
    20341 tgacggtgca gttcagcggg gcccggtacg ccccggtgcc gttgtagccc cagctgaacg
    20401 cgccgcccgg cgcgatgcca ccggcccagc tcttcttgac cgcgacgtag tggtcgccgc
    20461 tgcgggtgac gtcggcgtcc cacgagctgc tgatgctggt gcccgagggg aggtcgaact
    20521 cgatgcgcca ggtgctgacc ggggcgtccg aaccgttggt gatggtcacc cgcgtctcgt
    20581 gaccggtgcc ccagtcctgc accttcgtga aggtggtggt cacgctgccg gcgccgaagg
    20641 ccgaggtcat cggaaccgcg gcaacggtca cggcgaccac ggcgctggcc cagagggcac
    20701 ggcggagtga tcttctcatg cggcgtctcc ctaaacagtt aggaaacttt ccagaaggtg
    20761 gttgagacgc tactcacgcc gtcatgagtt cgtcaagatg tacgtgtatc gatttccgta
    20821 ccggatctcc gccggtcagc gggatgaacc cggtccgcga ccggtcgtgg acggggcgtc
    20881 gggccgcggc cacccggtgt tcaccctccc ggtcggcccg gcgtctgccg gcgtacggct
    20941 acgcggcggt aacctcgccg gcatgagcgt cttcgacatc gggatcaacg ccctcgccgg
    21001 cggtccggcc aacctctccg accaccgggg gcgcgcgctc ctggtggtga acgtggcctc
    21061 ccagtgcggc ctcacaccgc agtacgccgg cctgcagaag ttgtacgacg cctacgccgg
    21121 gcgcgggctg gtggtgctcg gggtgccgtg caaccagttc gccgggcagg agcccggcac
    21181 ggccgacgag atcggcgagt tctgccggat ctcctacggg gtgagcttcc cgttgaccga
    21241 gaaggtcgag gtgaacgggc ccggccgaca cccgctgtac gcgctgctca cccaggccac
    21301 cgacgccgac ggacacaccg gagacgtccg ctggaacttc gagaagttcc tcgtcgcgcc
    21361 ggacggcacg gtggccgcgc ggttcgcgcc cacggtcgag ccggacgccc cggagttgca
    21421 cgcggcgatc cagcgggtcc tgccggccac gacctgagcc ggggcacccg cccctacacc
    21481 tcgcctcgac cgggtcgatg gcacgtccgt ccacactgcg gaggcgacca ccgtcccgca
    21541 catcgacgac ccgggagtgc catgaaaccg accagccggc ccatcggcta ctggctacgc
    21601 cacctgcaca acctgatcga ggcgcagttc gaggccgccc tcgccgagga gcggctcggc
    21661 cggcggcact ggcagaccct gcacctgctg cacgaggagg cacggacgcc cgcccagttg
    21721 acggaggccc tggccccgtt cggcgcggac ggcggcggca ccgtggacga tctgaccgca
    21781 cggggctggg tggcccgggg agacgacggc cggctcaccc tgaccacgga gggccggacc
    21841 gcccacacgc aggtggccgc ccgggtcga
//
