LOCUS       NZ_BNBR01000005        41038 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces griseosporeus strain JCM 4766 sequence05, whole genome
            shotgun sequence.
ACCESSION   NZ_BNBR01000005
VERSION     NZ_BNBR01000005.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces griseosporeus
  ORGANISM  Streptomyces griseosporeus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 764915)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 112X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014656055.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 05:04:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,365
            CDSs (total)                      :: 7,282
            Genes (coding)                    :: 7,186
            CDSs (with protein)               :: 7,186
            Genes (RNA)                       :: 83
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 96
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 96
            Pseudo Genes (frameshifted)       :: 41 of 96
            Pseudo Genes (incomplete)         :: 61 of 96
            Pseudo Genes (internal stop)      :: 11 of 96
            Pseudo Genes (multiple problems)  :: 15 of 96
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:46:46
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 238169
            Orig. end                         :: 279207
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BNBR01000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..41038
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="False"
                     /product="PKS-like"
                     /product="butyrolactone"
                     /region_number="1"
                     /rules="(t2pks2 or ksIII)"
                     /rules="AfsA"
                     /tool="antismash"
     cand_cluster    1..41038
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(t2pks2 or ksIII)"
                     /detection_rules="AfsA"
                     /kind="neighbouring"
                     /product="PKS-like"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..41038
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21038](+)"
                     /cutoff="10000"
                     /detection_rule="(t2pks2 or ksIII)"
                     /neighbourhood="20000"
                     /product="PKS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..21038
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(t2pks2 or ksIII)"
                     /neighbourhood="20000"
                     /product="PKS-like"
                     /protocluster_number="1"
     misc_feature    complement(2366..2379)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.22"
                     /tool="antismash"
     misc_feature    2468..2480
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            2537..3253
                     /locus_tag="IE308_RS24105"
                     /old_locus_tag="GCM10018783_48910"
     CDS             2537..3253
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015659244.1"
                     /locus_tag="IE308_RS24105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_48910"
                     /product="DUF3566 domain-containing protein"
                     /protein_id="WP_190219531.1"
                     /transl_table=11
                     /translation="MSGATGAGPAGTSTGTDGGGRGSAAQATPASDPHTTNLKAVKPSA
                     ADSPDTHGSQGGTVTDTRGQQAQAASPLPGERQPQQPAGPYHPPQAYPAQEGQAQTGTV
                     RRPRTGARTTPRVRKARLRVAKADPWSVMKVSFLLSIALGICTIVAAAVLWMVMDAMGV
                     FSTVGGTISEATGSNESNGFDLQSFLSLPHVLMFTTIIAVIDVVLATALATLGAFIYNL
                     SAGFVGGVELTLAEDE"
     tRNA            3353..3426
                     /anticodon=(pos:241556..241558,aa:Ile,seq:gat)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="IE308_RS24110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GCM10018783_t00580"
                     /product="tRNA-Ile"
     gene            3353..3426
                     /locus_tag="IE308_RS24110"
                     /old_locus_tag="GCM10018783_t00580"
     gene            complement(3473..5062)
                     /locus_tag="IE308_RS24115"
                     /old_locus_tag="GCM10018783_48920"
     CDS             complement(3473..5062)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE308_RS24115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10018783_48920"
                     /product="hypothetical protein"
                     /protein_id="WP_190219532.1"
                     /transl_table=11
                     /translation="MRFRRTLISAAAAGLLATAGTAATGTAVAADAPQLKLQVDNPREF
                     YFLPPDGAENTSNDYVTELRVDSVGAEVRDVEIVYDLSSLKDKVTVDRLDRDCHRTDWV
                     VTCAHQDFTGSGLLRPFLLRSAKGVPLGEIGSIKESVTSSNAGSAEHTRRVFNGKPEPR
                     YGAHASYTIPDSERGRFPDLSPVIGNVGQVPVPDGVLLHVGLSDQDFTGERYSNCYYRT
                     YIGAGASAYCWFDTDLAPGTAYTTDGVFSGATDPCCRVKGRYYYALFPLGNPPRDWDKG
                     TRGTGRVLGLKPVPASAAQQPYGSLPFISAGDWQTDWKQQPITLKGKLGKVTEIRVPYP
                     QSLGPDNPWELYDGADGLDLERQMRVEVTLPEGVSLYPTQPGEQTEEDLCNYAADGHTI
                     TCRIHDWAYLRVRFDKKVEGAQGSAKLVYPDDKLKDPDLTNNTAPITADITGTPTPSTS
                     PTPSPSPTPTSTPSPSVTPTTAPTPSTPPGETPPTGSMAATGTPATPLLATTAAAAVTL
                     GATLLAIRRRRT"
     gene            complement(5283..5687)
                     /locus_tag="IE308_RS24120"
                     /old_locus_tag="GCM10018783_48930"
     CDS             complement(5283..5687)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010032677.1"
                     /locus_tag="IE308_RS24120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_48930"
                     /product="DUF6344 domain-containing protein"
                     /protein_id="WP_229909021.1"
                     /transl_table=11
                     /translation="MARNQVKQLWTVIVTAFLALCTALGLITTTATAAVAQTEPARNSG
                     TGEAESPQVTIPAQSPWSRSPWSHARALPPTMKQRIHAEAHGKSPSCRHRPLPDADAAT
                     ATVPADDAAPAPDAPCDTLTATAPRVPLQR"
     gene            5994..6122
                     /locus_tag="IE308_RS37030"
                     /old_locus_tag="GCM10018783_48940"
     CDS             5994..6122
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003999697.1"
                     /locus_tag="IE308_RS37030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_48940"
                     /product="DLW-39 family protein"
                     /protein_id="WP_003999697.1"
                     /transl_table=11
                     /translation="MKKLLLVALAAIGGLLVYRQIQADRAEQDLWTEATDSVPTGS"
     gene            6211..7605
                     /locus_tag="IE308_RS24130"
                     /old_locus_tag="GCM10018783_48950"
     CDS             6211..7605
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014673788.1"
                     /locus_tag="IE308_RS24130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_48950"
                     /product="hypothetical protein"
                     /protein_id="WP_229909022.1"
                     /transl_table=11
                     /translation="MGRYRANAVVRGGVAAAVAGALVAGVPASAGAAGPGGYGFDPAGR
                     RLSAATTTSAAGLLEPGGTYRSSLPTEGRTYYRLALDATSTAYVAVTAVPPSGADVAVT
                     DGIRVALQDADGHYCSTDTASVGAARSPRPVTAWGTREAGNGRPACQDAGTYYVVVERL
                     RSSSSSSSSSPFSSSAWELELTAAVEAPLKEAGPTTAPGTEASASTPPLAGPARKRPGG
                     NGFAGAAVVGQGVWSDTLTTGRTLFYKVPVDWGQRLSVTAELGSAPDDASGLVAGALGL
                     SLYNPARVPVDDATVSYGGSQKSAALDDLPPVRYRNRYAVHDEVSGMRFAGTYYLAVHL
                     SERVAERFGAGPFDLTLRVRVAGAERQPGPGYAGESTPADTFRVTDEERRAAALGGGGF
                     AGGVTGGSSGGADAGGGTAMKALAAGGIGAGTLLLAVLGGWTLVARRRAGSAAAQTRVS
                     AQNPTA"
     gene            complement(7569..8921)
                     /locus_tag="IE308_RS24135"
                     /old_locus_tag="GCM10018783_48960"
     CDS             complement(7569..8921)
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014673789.1"
                     /locus_tag="IE308_RS24135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_48960"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_190219533.1"
                     /sec_met_domain="Pkinase (E-value: 3.8e-39, bitscore:
                     130.0, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEVFAGRYELVDPIGRGGVGAVWRAWDHRRRRYVAAKVLQQSDA
                     HSLLRFVREQALRIDHPHVLAPASWAADDDKVLFTMDLVTGGSLVHLVGDYGPLPPLFV
                     CTLLDQLLAGLAAVHAEGVVHRDIKPANVLLEATGTRRPRLRLSDFGIAMRLGEPRLTE
                     TNLVVGTPGYLAPEQLLGAEPDFPADLFAVGLVALYLLEGARPDAKALIQYFADHGTPG
                     APKGIPEPLWQVVATLLQPDPAARFRTATGARKALAAAVELLPEPGPDDELIEIFDQIG
                     PLPQGYGPDGPENAARGARSDGTGPTDVQRIAPQGAAADPASPTPSPSAPAPPPAPTPP
                     PTPTPTPRPPSAPPAPPYGAHPAYGGHPTYGASTATYTAPNPYVPPAPLQAPPTPGPVG
                     TPGTPQDPPAQTPRAAHARRRRPGPPAGIAVPLLLLALACYAVGFWALTRV"
     misc_feature    complement(8073..8075)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(8981..9529)
                     /locus_tag="IE308_RS24140"
                     /old_locus_tag="GCM10018783_48970"
     CDS             complement(8981..9529)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569181.1"
                     /locus_tag="IE308_RS24140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_48970"
                     /product="DNA-binding protein"
                     /protein_id="WP_110629215.1"
                     /transl_table=11
                     /translation="MDAAQQEATARARELQRNWYGEPLGALFRKLIDDLGLNQARLAGV
                     LGLSAPMLSQLMSGQRAKIGNPAVVQRVQLLQELAAQVADGSVSAAEATERMDEIKRSQ
                     GGSVLSNTTHTTNSSGAPTVKRVVREIQSLLRSVAAAGDILQAADTLAPTHPELAEFLR
                     VYGAGRTSDAVAHYQSHQS"
     misc_feature    complement(9592..9605)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.1"
                     /tool="antismash"
     misc_feature    complement(9625..9638)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.96"
                     /tool="antismash"
     misc_feature    complement(9627..9640)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.3"
                     /tool="antismash"
     tRNA            9713..9785
                     /anticodon=(pos:247915..247917,aa:Ala,seq:tgc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="IE308_RS24145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GCM10018783_t00590"
                     /product="tRNA-Ala"
     gene            9713..9785
                     /locus_tag="IE308_RS24145"
                     /old_locus_tag="GCM10018783_t00590"
     misc_feature    9811..9825
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.13"
                     /tool="antismash"
     misc_feature    9813..9824
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.93"
                     /tool="antismash"
     gene            complement(9921..10658)
                     /locus_tag="IE308_RS24150"
                     /old_locus_tag="GCM10018783_48980"
     CDS             complement(9921..10658)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143838.1"
                     /locus_tag="IE308_RS24150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_48980"
                     /product="DUF4232 domain-containing protein"
                     /protein_id="WP_190219534.1"
                     /transl_table=11
                     /translation="MSTIRNSRTRLLTAAASVALAALTLTACNGDGTGVTDEGAAPSAS
                     RPTPTAPTTSAPTAPSSSGTGTGTGTGSSASAPASKPTAQHPSEPAAKNPAKPPASAGK
                     PVTCEGSTLKTVAAPLNRPVNHMLLTVTNTGSSPCHLYAYPAVRFGEAQAVPPVVEESH
                     PQAVVTLAPGESGYAAVLLSAADGSGAHGHTEKSLSVHFYGPSGSGSVGAAATPPLPAQ
                     GVFVDDSLRVTYWQQDLDDALTW"
     misc_feature    complement(10652..10666)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.77"
                     /tool="antismash"
     gene            10834..12174
                     /locus_tag="IE308_RS24155"
                     /old_locus_tag="GCM10018783_48990"
     CDS             10834..12174
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020134372.1"
                     /locus_tag="IE308_RS24155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_48990"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_190219828.1"
                     /transl_table=11
                     /translation="MEDMVSGGLEDGFAALLRELKDRSGLSYGALAKRLHMSTSTLHRY
                     CNGAAVPNEYAPVERLARVCRATPEELVELHRRWVLADAARGRGAERTEPSRPPAPTGT
                     PVPPQPPATPEPVAPASDPAPDTPVVETTPSPASPPRRRRPVWLAAASAVVVLGAVGLA
                     LHPFAGPGRGDDGDRQAAGATAGAAPGSPAGGAGTAGSRTPSPSATPSPSPSAGGTSRG
                     PSARPSASAAASAPASPSAGSAGDTTAVPLAVGVRPYVYVSPCSQHFLVDSEPQQVGPP
                     AGEQDARRFADAYGAVSSDEQRIAVTVQGTGKDTVVLQALHVRVVAKGAPLAWNDYSMG
                     VGCGGDVQTESFDIDLDSGSPTVAVGSARRDFPYKVSESDPEVFYITARTRAHDVRWEL
                     ALDWSSGPRHGTIRIDNRGVPFRTSAGAGRPGYDYPLGGGEWIPRVQ"
     gene            12347..13051
                     /locus_tag="IE308_RS37035"
                     /old_locus_tag="GCM10018783_49000"
     CDS             12347..13051
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007266160.1"
                     /locus_tag="IE308_RS37035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49000"
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_229909023.1"
                     /transl_table=11
                     /translation="MPYPAAAQFLRTAIPDIIRAYQSALRAVRSPLATRKEAWPKCRDQ
                     AQAIVEDCVIALTGKQPPAPAEARRYSHLVGVDRATQGIAVAESVRAVDILWSAMQPAV
                     RSAVQCEAAARRTAALLLISTVFRASSGSRLYAGAVGYGDAVPRLSEDVADENAGAEAT
                     GETPVESPACAGLSQREKQVLERVARAMTNSQIARDLGIETATVKRHLNNIYAKLQADS
                     RIDAINKAYGRR"
     gene            complement(13104..14039)
                     /locus_tag="IE308_RS24165"
                     /old_locus_tag="GCM10018783_49010"
     CDS             complement(13104..14039)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013226.5"
                     /locus_tag="IE308_RS24165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49010"
                     /product="UbiA family prenyltransferase"
                     /protein_id="WP_190219535.1"
                     /sec_met_domain="ubiA (E-value: 5.8e-22, bitscore: 73.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEITNGIRIPKAQPHFIFRYARLSLIEARPTVQIVFLLRYALGA
                     AFSTRQHGASPAQLAAGTLAWWLAVIAAYLINGVMDVKEDRANGSVRPIARGDLPERPA
                     AFITAGTALGALALAQFVPGLTLWIAAFLLLGWIYSAPPFPAKRWSTACALVVFGLGWT
                     SFAGGAATAGGELDTAGLVFATVMSAWMAMVGSVVKDLSDVDGDATGGRRTVAVRYGAR
                     PARALGAAGALSVGTAAVLAALLWAQSILVAMVPVAVGAVCVVTQIVRTARVDNADKRT
                     RRSAYRAFMRTQYTANLVMVAVLLLDRWPA"
     gene            14231..15697
                     /locus_tag="IE308_RS24170"
                     /old_locus_tag="GCM10018783_49020"
     CDS             14231..15697
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016644871.1"
                     /locus_tag="IE308_RS24170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49020"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_190219536.1"
                     /transl_table=11
                     /translation="MVDVIVAGGGPVGLMLACELRLAGVDVLVLDRLAERVPHSKALGM
                     HARTLEVLDQRGLVDRFLEGHKRAPATHFAGLRPLEFDASDTRHPYMLLIPQAHTERLL
                     AERAAELGVRIRYGTEVTGLAQDADGVDVEVAGGERLRARFLAGCDGSRSTVRRVLGVG
                     FPGTPATVTAMIADVSLDEPPAQPRLLARFPGGQAGVLEYAPGRYRAMTIQYDTPYDPV
                     ADGDNPVTFEEFREVFRAIAGTDHGMRDPLWVSRFGDAARQADRYRVGRVFLAGDAAHI
                     HNPSGGQGLNLGMQDAVNLGWKLAAVVRGQAPQELLDTYHDERHPIGARVLQNTHAQVA
                     LSRPGHAVDALRELFAELIRIDEVNDRLTRMISALDVRYPVAGAHPLTGARMPDVDLKT
                     ADGDTRLYPLLHSGRGVLLDLADDAALRTTARGWADRVDLVPAHGADPRLDGVAAVLVR
                     PDGHVAWAAPTDVTLPDALTTWFGPARGAR"
     gene            15750..16142
                     /locus_tag="IE308_RS24175"
                     /old_locus_tag="GCM10018783_49030"
     CDS             15750..16142
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03618.1"
                     /locus_tag="IE308_RS24175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49030"
                     /product="PPOX class F420-dependent oxidoreductase"
                     /protein_id="WP_190219537.1"
                     /transl_table=11
                     /translation="MSLIPESHLDLLRRPLFVHLATVRPDGGPQVNPMWCSWDGTHLRF
                     TSTRTRFKFRNVTADPRVAVSVHDPDEPYRYLEIRGVVERIDDDSSGAFFFRLAERYGR
                     ELGGRLPPDVRERVVYVVRPTAVSHQ"
     gene            complement(16129..16668)
                     /locus_tag="IE308_RS24180"
                     /old_locus_tag="GCM10018783_49040"
     CDS             complement(16129..16668)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013053.5"
                     /locus_tag="IE308_RS24180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49040"
                     /product="cysteine hydrolase family protein"
                     /protein_id="WP_190219538.1"
                     /transl_table=11
                     /translation="MTDAQFTADSRTALILIDLQHWILEMHAWQPRPASDVVDACARLR
                     AAFAPVIHVRYLRADGADGGPDAPANQLHERCAPGPDDLLVTKHGLDAFEGTGLAAHLA
                     ASGVTGVVLAGLSTAHGVAATARTALASGLAVTVVSDATATVTAAEQDAVLGELAGAGA
                     AVRTVDEVLAGLVTGG"
     misc_feature    16776..16787
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.88"
                     /tool="antismash"
     gene            16813..18021
                     /locus_tag="IE308_RS24185"
                     /old_locus_tag="GCM10018783_49060"
     CDS             16813..18021
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012371.5"
                     /locus_tag="IE308_RS24185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49060"
                     /product="serine hydrolase"
                     /protein_id="WP_190219539.1"
                     /transl_table=11
                     /translation="MKLRADRLERLGNYFSRLTDEGKIPGWSAMVSQHGETVHESSGGM
                     ANIAAGIPMTADSIFRTWSLSKPMTSVAFMRLVEEGLVGLNDPVADYLPAFRDQRVYRA
                     GLPAAPITEGLVEPMRMWHLLTHTAGLGYGAHQSHAVDTLYVNDGYTVEPPAGTGLAEA
                     VEKWAAFPLRFQPGTAWNYGVSTDVLGRVIEVVSGKRLDEYMRESFFEPLGLKDSGFWV
                     EARNKDRYAEIYTPTADGGIEHNPAASAYPTEAPLFLSGGGGIYTTVADYMKFLNMLAN
                     GGRVGHGSDHYLSPLTVESIRSNHLPRNVTLGSGFGSWGVPAVNELMPAAGFGLGFMTV
                     QQPQEAHLLTREGEFFWLSMSSANFFVDPASGVCALVSPQLYPSRTLPITNRLRQFVYQ
                     AYC"
     gene            18036..18449
                     /locus_tag="IE308_RS24190"
                     /old_locus_tag="GCM10018783_49070"
     CDS             18036..18449
                     /EC_number="3.1.2.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 4HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024675.5"
                     /locus_tag="IE308_RS24190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49070"
                     /product="thioesterase family protein"
                     /protein_id="WP_110629223.1"
                     /sec_met_domain="4HBT_2 (E-value: 1.2e-19, bitscore: 66.3,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSTMPMPVEVSLRWGDVDSYGHVNNCEIVRIIEEARMRWLMSS
                     GVFDGETAVVAAHEIGYLRPLRYSLDPVDVEVWTSNVRRSSFEFNFRILNSDRQVSVKA
                     VSRMVMFDLEKQESYAIGPRLRGFLTAACGERL"
     gene            18519..19946
                     /locus_tag="IE308_RS24195"
                     /old_locus_tag="GCM10018783_49080"
     CDS             18519..19946
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.5"
                     /locus_tag="IE308_RS24195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49080"
                     /product="MFS transporter"
                     /protein_id="WP_190219540.1"
                     /transl_table=11
                     /translation="MSTVVSKAPPREAQSTMGTLGLTIVLVTAALTMIDAAIVNVALPS
                     IQATLHTDASVSQFVVSGYVIAYAILLVLGGKLGDRHGRRRLLQIGVLAFTLTSLACGL
                     APSIEFLIVARALQGASAAFLLPQALSTIQTSLAESAKTRAIGLYGAIGGLSAAAGQLL
                     GGVLVWADIAGLDWRPIFLVNVPLGILALIGAQTHVPDTKAAGGQSMDVGGTVLLGVAV
                     LALLIPLSVGRQAHWALWCWLLIAVAVVAGVALWRYERRLEQQGRTPLIPPSLVRMRPV
                     NRGLLILGGGFLVFSGFSFAVPLALQDGNGMSAVESGLSVAPLAVGAFLGSLRAPKLMA
                     KVGMRTVQVGAVVQIAGLALLIAAARLWWPHIRFYELVVAMFLVGVGNGLFIPPVFRTI
                     LSSLPPDQAGAGSGIMSTTQQTSVAVGTAVLGQVFITFASGGDMNLGFVAVTATYLVVG
                     VLICLFGGAALTQKTGD"
     cand_cluster    18785..29756
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    18785..29756
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[23784:24756](+)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      23785..24756
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="2"
     gene            20001..21038
                     /locus_tag="IE308_RS24200"
                     /old_locus_tag="GCM10018783_49090"
     CDS             20001..21038
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PKS-like: ksIII"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE308_RS24200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10018783_49090"
                     /product="hypothetical protein"
                     /protein_id="WP_190219541.1"
                     /sec_met_domain="ksIII (E-value: 1.7e-44, bitscore: 147.5,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLIGDLYLNGCAVSYPTTRVPVSEALARGLIRDADETLGDPAVPV
                     FEESAPAADLAVDALRRSLKSTGTDAADVDVLIQCGWWHQGYDIWSAAHYVAHQVGALG
                     AVPMNLSQGCNAPMAALELTVRAMRADSAIRVGAVTTADAMRFPQVDRWNLNYGCVHGD
                     AGTAWLVAREPAGPHAFRVLSVASKAAPELEMMNRAGLAPTPGPALREGGTVDLKAAKK
                     AYLTEFGMDGFIGRSRDCLTGSVRQALDEAGLDGSERRIRAVSVPRLSGKIFETVYRAQ
                     LAPFFGEDKLRWWGDRTAHLGVADVGANIEDTAAELPLEPGDITVVVNAGGGYTWSCLV
                     LEHAA"
     gene            21130..21411
                     /locus_tag="IE308_RS24205"
                     /old_locus_tag="GCM10018783_49100"
     CDS             21130..21411
                     /GO_function="GO:0000036 - acyl carrier activity [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PP-binding (20-80). E-value: 1.4e-13.
                     Score: 43.0. Matches aSDomain:
                     nrpspksdomains_IE308_RS24205_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.5"
                     /locus_tag="IE308_RS24205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49100"
                     /product="acyl carrier protein"
                     /protein_id="WP_110629226.1"
                     /sec_met_domain="PP-binding (E-value: 4e-13, bitscore:
                     45.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTITQVSDETVRTTTLDIIVDELELDVEPEEVDLKADLIEVYGAD
                     SLGLIQVLARVNKQLGIRVPREKAVDLRTVELLIQQILDIRDGKDGDQ"
     aSDomain        21190..21369
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS24205_PP-binding.1"
                     /evalue="1.40E-13"
                     /label="IE308_RS24205_PP-binding.1"
                     /locus_tag="IE308_RS24205"
                     /protein_end="80"
                     /protein_start="20"
                     /score="43.0"
                     /tool="antismash"
                     /translation="DELELDVEPEEVDLKADLIEVYGADSLGLIQVLARVNKQLGIRVP
                     REKAVDLRTVELLIQ"
     gene            21408..22661
                     /locus_tag="IE308_RS24210"
                     /old_locus_tag="GCM10018783_49110"
     CDS             21408..22661
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (84-401). E-value:
                     2.5e-44. Score: 143.8. Matches aSDomain:
                     nrpspksdomains_IE308_RS24210_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2fas"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267083.1"
                     /locus_tag="IE308_RS24210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49110"
                     /product="beta-ketoacyl synthase"
                     /protein_id="WP_190219542.1"
                     /sec_met_domain="t2fas (E-value: 5.3e-107, bitscore: 353.5,
                     seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 7.4e-38, bitscore:
                     125.9, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRARRVVVTGLGCVSSIGTGVQEFTEGIKAGLSGISEITSFDSG
                     DFPARLAGEVQGFDPAGIVRNIDVEQWGRTAHFAAAAARLALDDSGLELDEESRATAGA
                     IIGTTNGEAPSVDTLTQQWLDGGPSTLSADLVRKVPAGNIAAAAAEELGLYGETVVIPT
                     ACSAANYAIGSAADKIIAGEADVMVAGGADSVNRFTHAGFLSLGAVADGVPRPFDQDRS
                     GIVTAEGGAVLVLEELEHARARGAHIYAELLGYGLSCDAHHIVHPDAESIATCIRRAHT
                     NSGIVAEDVDYICAHGTGTPTNDITEVTATRLVFGDEHPPMSSIKSMLGHTMGAASGFG
                     AIACCKAIEDAFLPPTINLRTVDPAFGEGIDFVGGGAKAAAVRVAQNHGFAFGGNNAIT
                     IFGAYADREPVGAGEGPR"
     aSDomain        21660..22610
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS24210_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.50E-44"
                     /label="IE308_RS24210_PKS_KS.1"
                     /locus_tag="IE308_RS24210"
                     /protein_end="401"
                     /protein_start="84"
                     /score="143.8"
                     /tool="antismash"
                     /translation="LALDDSGLELDEESRATAGAIIGTTNGEAPSVDTLTQQWLDGGPS
                     TLSADLVRKVPAGNIAAAAAEELGLYGETVVIPTACSAANYAIGSAADKIIAGEADVMV
                     AGGADSVNRFTHAGFLSLGAVADGVPRPFDQDRSGIVTAEGGAVLVLEELEHARARGAH
                     IYAELLGYGLSCDAHHIVHPDAESIATCIRRAHTNSGIVAEDVDYICAHGTGTPTNDIT
                     EVTATRLVFGDEHPPMSSIKSMLGHTMGAASGFGAIACCKAIEDAFLPPTINLRTVDPA
                     FGEGIDFVGGGAKAAAVRVAQNHGFAFGGNNAITIF"
     gene            22658..23788
                     /locus_tag="IE308_RS24215"
                     /old_locus_tag="GCM10018783_49120"
     CDS             22658..23788
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2fas"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012337.5"
                     /locus_tag="IE308_RS24215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49120"
                     /product="beta-ketoacyl synthase N-terminal-like
                     domain-containing protein"
                     /protein_id="WP_190219543.1"
                     /sec_met_domain="t2fas (E-value: 2.1e-19, bitscore: 65.0,
                     seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 3.6e-12, bitscore:
                     41.8, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVTQQPYDTGQPAGTGELRISGVSVLSAAGVGLDALRDRLRGPE
                     PVLGGDEPCASDAADYAGLPGRVAAVPDFKITDYVPRKGTKNLDRTTRLGLAASTLLKR
                     ELSERTEIPEASWEATGIAMGTVVGSLRSSVELDVDILQGQGTDLVNPAVFPNTTMNCC
                     ASQIAIWHTFRGPNSTLANGTVSALSALRYAARLIRCGHAGRMLVGGVEELSPHTAWGT
                     RLKKEVQESVPVGEGAALVALEPAGPDAPPALATVTACEVLFARERTQAGYAEALGRAV
                     DRARQAAEAAGTGVELVLPGTVGTFLQGAEESVLDRFDAERVDVRAAVGECGGALGAMQ
                     LAAAVALGRPGTGVLITGIDESGAVAAAVLTIGERA"
     gene            23785..24756
                     /locus_tag="IE308_RS24220"
                     /old_locus_tag="GCM10018783_49130"
     CDS             23785..24756
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015700.5"
                     /locus_tag="IE308_RS24220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49130"
                     /product="AfsA-related hotdog domain-containing protein"
                     /protein_id="WP_190219544.1"
                     /sec_met_domain="AfsA (E-value: 2e-12, bitscore: 42.5,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTATTATAADVTATAGTRVRRDLVHRAHEQEVLVSPPWREPDGG
                     YGSRTVTAGISDYYRDHPVPHRLDALLLIEACRQAALSAAHAFEGLSENIAFFFNSIDM
                     EITDPGQLAAADEELTIRSEFERLRLRGDGSPKQITYTQYGTDTSGRKLVRTSMAVQGL
                     PKDRYPELRAYQRGGSPAPTTAALRSGQVRRADLGAPASVARTRVENVAIAGVRAEAGV
                     RVADLAPDLANAALFDHDYDHFPAMVLIEAGRQLALSGTDRPAGHVVTAVRAAFEHFAE
                     LDAPIRLEARQGERWVDVDCVQDGLVVTRMAFALSPAPAGEA"
     gene            24756..25454
                     /locus_tag="IE308_RS24225"
                     /old_locus_tag="GCM10018783_49140"
     CDS             24756..25454
                     /EC_number="3.1.3.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012905.5"
                     /locus_tag="IE308_RS24225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49140"
                     /product="HAD family hydrolase"
                     /protein_id="WP_190219545.1"
                     /sec_met_domain="HAD_2 (E-value: 6.2e-07, bitscore: 25.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPAIWTDFRGVLTPPLREGLRAYCVGKEFTPAQLGQCLRAIADR
                     YGCPDGMAVLDSGILSERQWAAEIERELAGRFGLTADLSRLGSEWWSDRRVDSVWLAAL
                     RRWRQAGAFVGLVSNLPVDWKPYFTAFLDWDGLFDDVLLSCDTGARKPDAALFRLAESR
                     TGLPPEAHVLVDDLDANVTGARRAGWTGVTGGGEHTPAAVERIDALVGAAAPRNHPPVR
                     IGAPHQGAGR"
     gene            25451..26161
                     /locus_tag="IE308_RS24230"
                     /old_locus_tag="GCM10018783_49150"
     CDS             25451..26161
                     /NRPS_PKS="Domain: PKS_KR (4-157). E-value: 4.9e-24. Score:
                     77.2. Matches aSDomain:
                     nrpspksdomains_IE308_RS24230_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639947.1"
                     /locus_tag="IE308_RS24230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49150"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_190219546.1"
                     /sec_met_domain="adh_short (E-value: 2.3e-40, bitscore:
                     133.8, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 8.2e-06, bitscore:
                     20.5, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 2.8e-33, bitscore:
                     111.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSRSVFVTGASRGIGEAIAKELNKQGYRVVGTARTTRPELEGVE
                     FVACDVRDPESVRTAVEQAREILGEIDIVVNCAGIMNDGPLLTQTQEGVQSVLDTNLNG
                     SINVVRETVPDMMANKWGRLVFVSSIVALWGSPGQTNYSASKSGLIGLARSLAWELGRA
                     GITSNVVLPGLIETDMISGLTERRRKEIISQTALRRTGTPEEVAALVAFLVSEEAGFIT
                     GASIPIGGGVGMGL"
     aSDomain        25463..25921
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS24230_PKS_KR.1"
                     /evalue="4.90E-24"
                     /label="IE308_RS24230_PKS_KR.1"
                     /locus_tag="IE308_RS24230"
                     /protein_end="157"
                     /protein_start="4"
                     /score="77.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="SVFVTGASRGIGEAIAKELNKQGYRVVGTARTTRPELEGVEFVAC
                     DVRDPESVRTAVEQAREILGEIDIVVNCAGIMNDGPLLTQTQEGVQSVLDTNLNGSINV
                     VRETVPDMMANKWGRLVFVSSIVALWGSPGQTNYSASKSGLIGLARSLA"
     CDS_motif       25469..25531
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS24230_0001"
                     /evalue="1.80E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE308_RS24230"
                     /protein_end="27"
                     /protein_start="6"
                     /score="11.0"
                     /tool="antismash"
                     /translation="FVTGASRGIGEAIAKELNKQG"
     CDS_motif       25823..25882
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS24230_0002"
                     /evalue="1.60E-08"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE308_RS24230"
                     /protein_end="144"
                     /protein_start="124"
                     /score="27.0"
                     /tool="antismash"
                     /translation="VFVSSIVALWGSPGQTNYSA"
     gene            26161..26565
                     /locus_tag="IE308_RS24235"
                     /old_locus_tag="GCM10018783_49160"
     CDS             26161..26565
                     /EC_number="4.2.1.-"
                     /GO_function="GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019589.5"
                     /locus_tag="IE308_RS24235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49160"
                     /product="3-hydroxyacyl-ACP dehydratase FabZ family
                     protein"
                     /protein_id="WP_190219547.1"
                     /transl_table=11
                     /translation="MSTTTYPVRPGARRMPLVAVDDVRAAGKGFVGRKTIDPGDPYLRG
                     HFPSLTVYPGVFLVESLQQMLEVHLDGALGGVELVELGSVRFSRPALAGDEVVIEAEVD
                     GDRDRLVTKATCSSGGQRLARITATWRCRP"
     gene            26562..27035
                     /locus_tag="IE308_RS24240"
                     /old_locus_tag="GCM10018783_49170"
     CDS             26562..27035
                     /EC_number="4.2.1.-"
                     /GO_function="GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE308_RS24240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10018783_49170"
                     /product="3-hydroxyacyl-ACP dehydratase FabZ family
                     protein"
                     /protein_id="WP_190219548.1"
                     /transl_table=11
                     /translation="MTTTTYPDPADLLPYGHPALQVDRIVRHEPGALEAVKAVTYHELD
                     AHVGDSRPGRFPASLTLESFLQACGLLLMRETADAGPDARPLLIFGSARGVRVTGAARA
                     GELLVHSVELVDRDEETATFTGVSRAGDGRTVVEVDRAITLLRPAGSLDGTGR"
     gene            27163..28125
                     /locus_tag="IE308_RS24245"
                     /old_locus_tag="GCM10018783_49180"
     CDS             27163..28125
                     /EC_number="2.3.1.39"
                     /GO_function="GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_AT (9-294). E-value: 4.6e-38. Score:
                     123.2. Matches aSDomain:
                     nrpspksdomains_IE308_RS24245_PKS_AT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019356042.1"
                     /locus_tag="IE308_RS24245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49180"
                     /product="ACP S-malonyltransferase"
                     /protein_id="WP_229909024.1"
                     /sec_met_domain="PKS_AT (E-value: 5.3e-37, bitscore: 123.2,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVHHFVVTAPGQGVQRPGMLDPWLDAVPGARALVDDWSRAAGLDL
                     VEAGRDAALLADTAVAQPLIVAASLLAHRLLRERLPLAADEVLFAGHSVGELAAAAGAG
                     YLSPRDAVALARVRGAAMSAACALAPTGMAAVMPGRRAGASDEEIVAAVAAAGLTVANF
                     NGSHQFVAAGPADRVEALAEEPPPGTRVAPLNVAGAFHTEAMAPAVETFARAIAGVRIA
                     RSASAMVANGDGALLTGPEDLRRRLITQITSPVRWDLCTETIARLAPDALHLELAPAGP
                     LTRLLGRARPEARAVALGLPEDIDRAVAEAAERPLAGAR"
     aSDomain        27190..28044
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS24245_PKS_AT.1"
                     /evalue="4.60E-38"
                     /label="IE308_RS24245_PKS_AT.1"
                     /locus_tag="IE308_RS24245"
                     /protein_end="294"
                     /protein_start="9"
                     /score="123.2"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="PGQGVQRPGMLDPWLDAVPGARALVDDWSRAAGLDLVEAGRDAAL
                     LADTAVAQPLIVAASLLAHRLLRERLPLAADEVLFAGHSVGELAAAAGAGYLSPRDAVA
                     LARVRGAAMSAACALAPTGMAAVMPGRRAGASDEEIVAAVAAAGLTVANFNGSHQFVAA
                     GPADRVEALAEEPPPGTRVAPLNVAGAFHTEAMAPAVETFARAIAGVRIARSASAMVAN
                     GDGALLTGPEDLRRRLITQITSPVRWDLCTETIARLAPDALHLELAPAGPLTRLLGRAR
                     PEAR"
     CDS_motif       27430..27528
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS24245_0001"
                     /evalue="2.00E-11"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="IE308_RS24245"
                     /protein_end="122"
                     /protein_start="89"
                     /score="35.9"
                     /tool="antismash"
                     /translation="AGHSVGELAAAAGAGYLSPRDAVALARVRGAAM"
     CDS_motif       27586..27642
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS24245_0002"
                     /evalue="5.70E-01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="IE308_RS24245"
                     /protein_end="160"
                     /protein_start="141"
                     /score="3.4"
                     /tool="antismash"
                     /translation="AGASDEEIVAAVAAAGLTV"
     gene            28175..29719
                     /locus_tag="IE308_RS24250"
                     /old_locus_tag="GCM10018783_49190"
     CDS             28175..29719
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018888432.1"
                     /locus_tag="IE308_RS24250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49190"
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_110629234.1"
                     /transl_table=11
                     /translation="MRSAVEELTSLKREITEGPDAAATRRQRDKGKLTVRERIALLLDE
                     GSFHEVEPLRRHRAQGFGLERRRPHTDGVVTGWGTVEGRTVFVYAHDFRIFGGALGEAH
                     AEKIHKIMDMAIAAGAPLVSLNDGAGARIQEGVTALAGYGGIFTRNTRASGVIPQISVM
                     LGPCAGGAAYSPALTDFVFMVRDTSQMFITGPDVVKAVTGEEISQNGLGGADVHAETSG
                     VCHFAYDDEETCLAEVRYLLSLLPQNNRERPPAAPSGDPADRRCEELLDLVPADGNRPY
                     DMRRVIESLVDDGDYLEVHERWATNVLVALARLDGQVVGIVANQPQSLAGVLDINASEK
                     AARFVQMCDAFNIPIVTLLDVPGFLPGVDQEHGGIIRHGAKLLYAYCNATVPRIQLILR
                     KAYGGAYIVMDSRSVGADLSYAWPTNEIAVMGAEGAANVIFRRQIAGADDPEAMRARMV
                     KEYKAELMHPYYAAERGLVDDVIDPAETRQVLIRSLHMLRTKHADLPSRKHGNPPQ"
     gene            29751..29948
                     /locus_tag="IE308_RS24255"
                     /old_locus_tag="GCM10018783_49200"
     CDS             29751..29948
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014145079.1"
                     /locus_tag="IE308_RS24255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49200"
                     /product="acyl-CoA carboxylase subunit epsilon"
                     /protein_id="WP_229909025.1"
                     /transl_table=11
                     /translation="MTSATPLVRVERGHASDDELAALTVVLLSRTTAPAPAAGPTAPAV
                     PLWDRPERNAPYRPPVSWRR"
     gene            29977..30117
                     /locus_tag="IE308_RS24260"
                     /old_locus_tag="GCM10018783_49210"
     CDS             29977..30117
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE308_RS24260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10018783_49210"
                     /product="hypothetical protein"
                     /protein_id="WP_190219549.1"
                     /transl_table=11
                     /translation="MDGTHHGRPAPAGPHRTPPEQPGPPRALLAGEEERGDEPHIERGI
                     D"
     gene            30124..30867
                     /locus_tag="IE308_RS24265"
                     /old_locus_tag="GCM10018783_49220"
     CDS             30124..30867
                     /NRPS_PKS="Domain: ACPS (124-187). E-value: 1.5e-22. Score:
                     71.9. Matches aSDomain:
                     nrpspksdomains_IE308_RS24265_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1060: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014145781.1"
                     /locus_tag="IE308_RS24265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49220"
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="WP_229909026.1"
                     /transl_table=11
                     /translation="MTARQHTDVLPRPSPATALMASLLPARAVAAEAFGDGHDEDWFGQ
                     LLPAEARLMAGAGEKRRRDFAGVRVCAQRALRTLGHAPVPLLPGPRGEPRWPDGVVGSL
                     THCAGYRAAVVARPGPGLAGVGIDAEPHAPLDADVLEMVASPAERAHLALLARTRPGVH
                     WGRLLFCVKEAVFKAWYPAARCELGFLEADVRFTADGPHSADGRYGTDGMHGIVTATLT
                     RAGPFATVSGRWRVAGGVIATAVVI"
     aSDomain        30496..30684
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS24265_ACPS.1"
                     /evalue="1.50E-22"
                     /label="IE308_RS24265_ACPS.1"
                     /locus_tag="IE308_RS24265"
                     /protein_end="187"
                     /protein_start="124"
                     /score="71.9"
                     /tool="antismash"
                     /translation="VGIDAEPHAPLDADVLEMVASPAERAHLALLARTRPGVHWGRLLF
                     CVKEAVFKAWYPAARCEL"
     gene            30909..31430
                     /locus_tag="IE308_RS24270"
                     /old_locus_tag="GCM10018783_49230"
     CDS             30909..31430
                     /NRPS_PKS="Domain: Polyketide_cyc2 (10-169). E-value:
                     1.9e-21. Score: 68.9. Matches aSDomain:
                     nrpspksdomains_IE308_RS24270_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018529924.1"
                     /locus_tag="IE308_RS24270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49230"
                     /product="SRPBCC family protein"
                     /protein_id="WP_110629235.1"
                     /transl_table=11
                     /translation="MRLADSPGVECAAEIAADPQRVWELVSDIATSARHSPELQEVEWL
                     DGADGPAVGACFAGRNRNSGLGEWRTVSRITRMSRPHVFEWEVVHYNDRRHGEPLAVWT
                     YTLEPLADGSGTLVRHGMRIGSARGPLHDVVELHPEREEQIVTGRLALLRAGIQTTLAG
                     LRAEAEGRLV"
     aSDomain        30939..31415
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS24270_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="1.90E-21"
                     /label="IE308_RS24270_Polyketide_cyc2.1"
                     /locus_tag="IE308_RS24270"
                     /protein_end="169"
                     /protein_start="10"
                     /score="68.9"
                     /tool="antismash"
                     /translation="CAAEIAADPQRVWELVSDIATSARHSPELQEVEWLDGADGPAVGA
                     CFAGRNRNSGLGEWRTVSRITRMSRPHVFEWEVVHYNDRRHGEPLAVWTYTLEPLADGS
                     GTLVRHGMRIGSARGPLHDVVELHPEREEQIVTGRLALLRAGIQTTLAGLRAEAE"
     gene            complement(31457..32281)
                     /locus_tag="IE308_RS24275"
                     /old_locus_tag="GCM10018783_49240"
     CDS             complement(31457..32281)
                     /GO_process="GO:0006396 - RNA processing [Evidence IEA]"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010045534.1"
                     /locus_tag="IE308_RS24275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49240"
                     /product="NshR family nosiheptide/thiostrepton resistance
                     23S rRNA methyltransferase"
                     /protein_id="WP_190219550.1"
                     /transl_table=11
                     /translation="MTEPAIITNASDPAVQRIIDVTKHSRASIKTTLIEDTEPLMECIR
                     AGVQFIEVYGSSGTPLDPALLDLCRQREIPVRLIDVSIVNQLFKAERKAKVFGIARVPR
                     PARLADIAERGGDVVVLDGVKIVGNIGAIVRTSLALGAAGIVLVDSDLATIADRRLLRA
                     SRGYVFSLPVVLADREEAVSFLRDNDIALMVLDADGDLGVKDLGDRADRMALVFGSEKG
                     GPSGLFQEASAGTVSIPMLSSTESLNVSVSVGIALHERSARNFAVRRAAAQA"
     gene            complement(32340..33041)
                     /locus_tag="IE308_RS24280"
                     /old_locus_tag="GCM10018783_49250"
     CDS             complement(32340..33041)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019073557.1"
                     /locus_tag="IE308_RS24280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49250"
                     /product="DUF5324 family protein"
                     /protein_id="WP_110629236.1"
                     /transl_table=11
                     /translation="MTRIDSVRAATGSAKDSVLHAAEVVAPYADTAKERAAHYAHEARV
                     RLAPKVTLAAEQARVQYGAHLAPRLEQARTHVPPKVELAAQEAALRTRKAARQAADYSR
                     PMIEQAVAAAGPVRDEAATRAAAALVALRGQVTAEDIQKLVRKHERRARTGRAVRMLAV
                     LGLVAGGAFAAWKWWDKQANPDWLVEPPEATEVPESGRLTSVDGSAEAVLDPEVQAKEA
                     AEEAAKRDDQA"
     gene            33294..33827
                     /locus_tag="IE308_RS24285"
                     /old_locus_tag="GCM10018783_49260"
     CDS             33294..33827
                     /EC_number="5.2.1.8"
                     /GO_function="GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /GO_process="GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013002232.1"
                     /locus_tag="IE308_RS24285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49260"
                     /product="peptidylprolyl isomerase"
                     /protein_id="WP_190219551.1"
                     /transl_table=11
                     /translation="MAEQLYATLRTNHGDIRIRLFPHHAPATVRNFVELAQGEREWTHP
                     ATGAKTTAPLYDGTVFHRVMSGFMIQGGDPLGNGTGDPGYQFKDEFHPDLRFDRPYLLA
                     MANAGPGTNGSQFFITVAPTAWLNRKHTIFGEVADAAGRKVVDAIVSVPTNPRTHRPVE
                     DVVIESVAVETREG"
     gene            33933..34820
                     /locus_tag="IE308_RS24290"
                     /old_locus_tag="GCM10018783_49270"
     CDS             33933..34820
                     /EC_number="3.4.21.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130630.1"
                     /locus_tag="IE308_RS24290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49270"
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="WP_190219552.1"
                     /transl_table=11
                     /translation="MEQAPGGSRPEARTPPTCYRHPDRETGIRCTRCDRPICPECMVNA
                     SVGFQCPDCVRGTSGGGPSPAAARPRTIAGGSVSADPRLVTKVLIGINLAVFIAVQVSK
                     TVLNDVVLIGAWPPAPFHPTEGVAGGEWWRMVTSMFAHEAVWHFAFNMLGLWWLGGPLE
                     AALGRARYLALYFTSGLAGSALTYLLASPSSATLGASGAIFGLFGATAVLMRRLNYDMR
                     PIIALLVINLIFTFGWSIIAWQAHIGGLVAGVVVGYAMVHAPRDRRALVQYGTCALVLA
                     AVVLVTLLRTAQLT"
     gene            complement(35068..35322)
                     /gene="crgA"
                     /locus_tag="IE308_RS24295"
                     /old_locus_tag="GCM10018783_49280"
     CDS             complement(35068..35322)
                     /codon_start=1
                     /gene="crgA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569173.1"
                     /locus_tag="IE308_RS24295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49280"
                     /product="cell division protein CrgA"
                     /protein_id="WP_110629239.1"
                     /transl_table=11
                     /translation="MPKSRIRKKADYTPPPAKQAAAIKLENRGWVAPVMLAMFLIGLAW
                     IVVFYVTDGSLPIDSLNNWNIVVGFGFIAAGFGVSTQWK"
     misc_feature    35327..35341
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     gene            35445..36224
                     /locus_tag="IE308_RS24300"
                     /old_locus_tag="GCM10018783_49290"
     CDS             35445..36224
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009189609.1"
                     /locus_tag="IE308_RS24300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49290"
                     /product="DUF881 domain-containing protein"
                     /protein_id="WP_110629240.1"
                     /transl_table=11
                     /translation="MSNSADSPQPGSSAAHRGGFRPVRVLTVAVFALAGLLFFTSFQTA
                     KGTNIRTDTSLLKLSDLIQERSRKNKELDDSNAVLRDDVEALAGRDNGSTKADDDRLTA
                     LEKSAGARKLTGEAITVTLNDAPPNATAKLPGYPEPQPDYLVIHQQDLQAVVNALWQGG
                     AKGIKVMDQRLISTSAVRCVGNTLILQGRVYSPPYKIQAVGDPDRLQQALADSPAIQNY
                     MVYVNVYGLGWKVTEDGTVTLPGYTGTLDLHYAQPVR"
     gene            36293..36489
                     /locus_tag="IE308_RS24305"
                     /old_locus_tag="GCM10018783_49300"
                     /pseudo=""
     CDS             36293..36489
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004985878.1"
                     /locus_tag="IE308_RS24305"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49300"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSVVPWATEGTACTAGSGGICRETPGSRR"
     gene            36486..37124
                     /locus_tag="IE308_RS24310"
                     /old_locus_tag="GCM10018783_49310"
     CDS             36486..37124
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1249: carbamoyl phosphate synthase small subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003975083.1"
                     /locus_tag="IE308_RS24310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49310"
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="WP_110629242.1"
                     /transl_table=11
                     /translation="MSARILVVDNYDSFVFNLVQYLYQLGAECEVLRNDEVSTAHANDG
                     FDGVLLSPGPGKPEEAGVCIDMVRHCAATGVPVFGVCLGMQSMQVAYGGVVDRAPELLH
                     GKTSLVEHEGRGVFAGLPSPFTATRYHSLAAEPPTVPAELEVTARTRDGIIMGLRHREL
                     PVEGVQFHPESVLTEHGHRMLANWLAECGDEGAVARSAGLAPVVGRATA"
     gene            37121..38215
                     /locus_tag="IE308_RS24315"
                     /old_locus_tag="GCM10018783_49320"
     CDS             37121..38215
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003999684.1"
                     /locus_tag="IE308_RS24315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49320"
                     /product="class E sortase"
                     /protein_id="WP_190219553.1"
                     /transl_table=11
                     /translation="MTALRPEREDSYGPTPYEPYGTTSYGAQDGTYGDEAYGDGTYPDE
                     EHGDGTYDPYVPPADDETMALRVPPPPGSGSIAASDAPSASAATGVTPGGRAARRKAAK
                     RRRGRHGGPAQADPPAEEKPPAPLSRVEARRQARARKPGAGVVVSRAIGELFITTGVLM
                     LLFVTYQLWWTNVRAHAQAGKEASDLQQEWADGRRNPGVFAPGQGFAILYIPKLDVVVP
                     IAEGVSNKKVLDKGMVGHYGQDPLKTAMPGDKTGNFGLAGHRNTHGEPFRYINRLQPGD
                     EVVVETQDTYYVYKTTSTLPVTSPSNVSVLDPVPRGSGFTAPGRYITLTTCTPEFTSKY
                     RLIVWGKMVEERPRSKGKPDALVS"
     gene            38228..38974
                     /locus_tag="IE308_RS24320"
                     /old_locus_tag="GCM10018783_49330"
     CDS             38228..38974
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014673799.1"
                     /locus_tag="IE308_RS24320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49330"
                     /product="class E sortase"
                     /protein_id="WP_229909027.1"
                     /transl_table=11
                     /translation="MAATAEDTDTSPPPSPRRRRGTGRIAMTVSVLGELLITAGLVLGL
                     FVVYSLWWTNVIADRAANRQADKVRDHWAQGDGGTGGPGALDTKDGIGFLHVPAMKNGE
                     VLVEKGTSTKVLNDGVAGYYTDPVKAVLPTSGKEGNFSLAAHRDGHGAKFHNIDKLKKG
                     DPIVFETKDKWYVYKVYAVLPETSKYNVDVLAQVPKESGKKKPGHYITLTTCTPVFTSR
                     YRYVVWGELVRVDQVDSERTEPAELR"
     gene            complement(39045..41030)
                     /gene="pknB"
                     /locus_tag="IE308_RS24325"
                     /old_locus_tag="GCM10018783_49340"
     CDS             complement(39045..41030)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005483008.1"
                     /locus_tag="IE308_RS24325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_49340"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_190219554.1"
                     /sec_met_domain="Pkinase (E-value: 3.1e-56, bitscore:
                     186.0, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEPRRLGGRYELGQVLGRGGMAEVYLAHDTRLGRQVAVKTLRAD
                     LARDPSFQARFRREAQSAASLNHPAIVAVYDTGEDYIDGVSIPYIVMEYVDGSTLRELL
                     HSGRKLLPERAMEMTIGILQGLEYAHRNGIVHRDIKPANVMLTRTGQVKVMDFGIARAM
                     GDAGMTMTQTAAVIGTAQYLSPEQAKGEQVDARSDLYSTGCLLYELLTVRPPFVGDSPV
                     AVAYQHVREEPQAPSVFDPEITPEMDAIVLKALVKDPNYRYQSADEMRADIEACLDGQP
                     VGAAAAMGSVGYGGYPDDQPTTALRAEPGAAAGATTMLPPMNPDDGGYGYDDRPDRRRQ
                     KKSNASTILLVVAAVLVLVGAVLIGKWITSGGGAGNDTVPVPNFVGLTVDDARKQAVNS
                     DLKVTIKKEPCENQPLNNVCKQDPAFKTEVKKGDTVTLTVSTGAPKLPVPDVQGLSFEK
                     AKARLEEKGFEVEKKSEESDQTPGVVIDQDPKGDTELEKGSKITLTVAVAPATTTVPDV
                     SNGLSCDDAKARMVANDLVGTCVETQVTSQDQDGKVIGTDPSPGTEVKKGSEVQIKVGK
                     FQQQQTPVPTVRNQPLKDARKALQDAGFNNINVLGSQDDKAIVINQDPQGGTPADPASQ
                     TVTLTTVDFGGGGGNNNGDNGGGLFG"
ORIGIN
        1 gagatgcagc gctcctacct cgactacgcg atgtccgtca tcgtctcgcg tgcgctgccc
       61 gacgtccggg acggcctcaa gcccgtccac cgccgggtgc tgtacgcgat gtacgacggc
      121 ggctaccgcc ccgagcgcgg cttctacaag tgcgcccgtg tcgtcggcga cgtcatgggc
      181 aactaccacc cgcacggcga ctcctcgatc tacgacgcgc tggtgcgcct cgcccagccg
      241 tggtcgatgc ggatgccgct ggtggactcc aacggcaact tcggctcccc gggcaacgac
      301 ccggcggcgg cgatgcgcta caccgagtgc aagatggcgc cgctgtcgat ggagatggtc
      361 cgcgacatcg acgaggagac cgtcgacttc acggacaact acgacggccg ctcccaggag
      421 ccgaccgtcc tgccgtcgcg cttcccgaac ctgctgatca acggctcggc cggtatcgcg
      481 gtcggtatgg cgacgaacat cccgccgcac aacctgcgcg aggtcgccgc cggcgcccag
      541 tggtacctgg agaaccccga ggcctcgcac gaggagctgc tggacgcgct catcgagcgg
      601 atcaagggcc cggacttccc gaccggcgcg ctggtcgtcg gccgcaaggg catcgaggag
      661 gcctaccgca cgggccgcgg ctcgatcacc atgcgcgcgg tggtcgaggt cgaggagatc
      721 cagaaccgcc agtgcctggt ggtgacggag ctgccgtacc aggtgaaccc cgacaacctg
      781 gcgcagaaga tcgccgacct ggtgaaggac ggcaagatcg gcggcatcgc cgacgtccgc
      841 gacgagacgt cctcccgcac gggccagcgc ctggtcatcg tcctcaagcg ggacgcggtc
      901 gccaaggtcg tgctgaacaa cctgtacaag cacaccgacc tgcagaccaa cttcggcgcc
      961 aacatgctgg cgctggtcga cggcgtgccg cgcacgctgt cccttgacgc gttcatccgc
     1021 cactgggtga cgcaccagat cgaggtcatc gtccgccgta cgcgcttccg gctgcgcaag
     1081 gccgaggagc gggcgcacat cctgcgcggc ctgctgaagg ccctggacgc catcgacgag
     1141 gtcatcgcgc tgatccggcg cagcgacacc gtcgagatcg cgcgtacggg cctgatgggc
     1201 ctgctggaga tcgacgagat ccaggccaac gccatcctcg agatgcagct gcggcgcctc
     1261 gcggccctgg agcggcagaa gatcgtccag gagcacgacg agctccaggc gaagatcaac
     1321 gagtacaacc agatcctcgc ctcgccggtc cgccagcgcg gcatcgtcag cgaggagctg
     1381 gccgcgatcg tcgagaagta cggcgacgac cgcaagacca tgctggtgcc ctacgacggc
     1441 gacatgtcca tggaggacct gatcgccgag gaggacatcg tcgtcacggt cacccgcggc
     1501 ggttacatca agcggaccaa gaccgacgac taccgggcgc agaagcgcgg cggcaagggc
     1561 gtgcgcgggg caaagctgaa ggaagacgac atcgtcgacc acttcttcgt ctccaccacc
     1621 caccactggc tgctgttctt caccaacaag ggccgggtgt accgggcgaa ggcatacgag
     1681 ctgccggacg ccggccggga cgcgcgcggt cagcacgtgg ccaacctgct ggccttccag
     1741 ccggacgagg cgatcgccga gatcctcgcg atccgcgact acgaggcggc gccctacctg
     1801 gtcctggcga ccaaggcggg tctggtgaag aagacgccgc tgaaggacta cgactcgccg
     1861 cgcgcgggcg gtgtcatcgc catcaacctg cgtgagcggg aggacggcag cgacgacgag
     1921 ctgatcggcg cggagctggt ctcgtccgac gacgacctgc tgctgatcag caggaaggcg
     1981 cagtcgatca ggttcaccgc cacggacgac acgctgcggc cgatgggccg cgccacctcg
     2041 ggtgtcaagg gcatgagttt ccgtgaggga gacgaactgc tctcgatgaa tgtggtgcga
     2101 cccggtacgt tcgtgttcac tgccaccgac ggtgggtacg cgaagcggac ccgcgtcgac
     2161 gagtaccgcg tccagggccg cggcggcctc ggcatcaagg ccgccaagat cgtggaggac
     2221 cgcgggtcac tggtcggtgc gctggtggtc gaggagaccg acgagatcct cgccatcaca
     2281 ctctcgggcg gtgtgattcg tacgcgagtc aacgaggtca gggagacggg ccgtgacacc
     2341 atgggcgtcc aactgatcaa cctgggcaag cgcgatgccg tcgtcggtat cgcccgtaac
     2401 gccgaggcgg gccgcgaggc ggaggaagtc gacggcgatc tggccgtgga cgacaccgac
     2461 gccgagggtg ccgctgccac cggcacggac gagggtgagg cgccctcggc cgagtagcac
     2521 cgaggagtga gtcaacgtga gcggagccac gggcgccgga ccggccggta ccagtacggg
     2581 gacggacggc ggcggccgtg gctccgccgc gcaggccaca cctgcgagcg acccgcacac
     2641 caccaatctg aaagcggtca agccgtctgc ggccgactcg cctgacacgc atggatccca
     2701 ggggggaact gtgacggaca cccgaggcca gcaggcgcag gcggcgtcgc ccctgccggg
     2761 cgagcgccag ccgcagcagc cggccgggcc gtaccacccg ccgcaggcct acccggcgca
     2821 ggagggccag gcacagaccg gcaccgtgcg ccggccgcgc accggggccc gtacgacgcc
     2881 ccgggtgcgc aaggcgcgcc tgcgggtggc caaggccgac ccgtggtcgg tgatgaaggt
     2941 cagcttcctg ctctccatcg cgctgggcat ctgcacgatc gtcgcggcgg cggtgctgtg
     3001 gatggtcatg gacgccatgg gggtcttctc cacggtcggc ggcacgatct cggaggcgac
     3061 gggctcgaac gagtcgaacg gcttcgacct ccagtcgttc ctgtccctcc cccacgtcct
     3121 gatgttcacg acgatcatcg cggtcatcga cgtcgtcctc gcgacggcgc tggcgacgct
     3181 cggcgcgttc atctacaacc tctccgccgg cttcgtcggc ggcgtcgagc tgaccctcgc
     3241 cgaggacgag tgagccggcc cacgggcccc gggggtatcg attttgggac tgacggtccc
     3301 gtgcgctaat cttcaggagt cagcgcgcgg gacacacacc gcagagcgcg gcggggctat
     3361 agctcagttg gttagagcgc atccctgata aggatgaggt cacaggttca aatcctgtta
     3421 gccccacagc ctgaaagaac cccggtcctg taggaccggg gttctttcgt gttcaggtgc
     3481 ggcggcggcg tattgccagc agggtcgcgc ccagggtgac tgctgcggcg gctgttgtgg
     3541 ccagcagggg ggtggcgggg gtgcccgtgg cggccatgga gccggtcggc ggggtctcgc
     3601 cggggggcgt cgacggggtg ggggccgtgg tgggcgtcac cgacggggac ggggtcgagg
     3661 tcggggtcgg ggacggagac ggcgtggggc tggtggaggg ggttggggtg cccgtgatgt
     3721 cggcggtgat cggggccgtg ttgttggtca ggtccgggtc cttcagcttg tcgtccgggt
     3781 agacgagctt cgccgagccc tgcgcgccct cgaccttctt gtcgaagcgg acccgcaggt
     3841 acgcccagtc gtggatgcgg caggtgatgg tgtggccgtc cgccgcgtag ttgcagaggt
     3901 cttcctcggt ctgctcgccc ggttgtgtcg ggtagaggct gacgccctcc ggcagggtca
     3961 cctccacccg catctgccgc tccaggtcca gcccgtcggc gccgtcgtac agctcccatg
     4021 ggttgtccgg gccgaggctc tgcgggtagg gcacccgtat ctcggtgacc ttgccgagct
     4081 tgcccttgag cgtgatcggc tgctgcttcc agtcggtctg ccagtcgccg gcggagatga
     4141 acggcaggga gccgtagggc tgctgtgcgg cgctcgcggg gaccggcttc aggccgagga
     4201 cgcggccggt gccacgggtg cccttgtccc agtcgcgggg cgggttgccc agcgggaaga
     4261 gggcgtagta gtagcggccc ttgacccggc agcaggggtc cgtcgcgccg ctgaagacgc
     4321 cgtccgtggt gtaggcggtg ccgggggcca ggtcggtgtc gaaccagcag taggcggagg
     4381 cgccggcgcc gatgtaggtg cggtagtagc agttgctgta ccgctccccc gtgaagtcct
     4441 ggtcggagag gccgacgtgc agcaggacgc cgtccggcac cgggacctgg ccgacgttgc
     4501 cgatcaccgg cgacaggtcg gggaaccggc cgcgctcgga gtccgggatg gtgtacgacg
     4561 cgtgcgcgcc gtagcggggc tccggcttgc cgttgaagac gcggcgggtg tgctccgcgg
     4621 aaccggcgtt ggaactggtg acgctctcct tgatgctgcc gatctcgccg agcgggacgc
     4681 ccttggccga gcgcaggagg aagggtctga gcaggcccga gccggtgaag tcctggtggg
     4741 cgcaggtgac gacccagtcg gtgcggtgac agtcacggtc cagccggtcg acggtgacct
     4801 tgtccttcag cgaggagagg tcgtacacga tctcgacgtc gcggacctcg gccccgacgg
     4861 agtccaccct cagctcggtc acgtagtcgt tggacgtgtt ctccgcgccg tccgggggga
     4921 ggaagtagaa ctccctgggg ttgtccacct ggagcttgag ttgcggtgcg tcggcggcga
     4981 ccgccgttcc cgtggccgcc gtaccggccg tggcgagcag ccccgcggcc gccgcggata
     5041 tgagcgtccg tctgaaacgc actgaagcgt ccccctgttc ggccctgtgc cgggcgatcg
     5101 gtgagtcctt ctgccacgta cagggactgc tggggtccgc gagaagttgt agagggccga
     5161 cgaggcgagg aagaaaggct ggacacacgg cgacggcccg gctgctcggg tgagctgccg
     5221 ggccgttttc cgcgtgcagg actgctgtac gcaagtcgcc gtccggggtg ctgggcgctg
     5281 cctcagcgct ggagcgggac tctgggcgcg gtcgcggtga gggtgtcgca gggggcgtcg
     5341 ggcgccgggg cggcgtcgtc ggcggggacg gtcgcggtgg ccgcgtcggc gtcggggagc
     5401 ggacggtgcc ggcagctggg ggacttgccg tgggcctccg cgtggatgcg ctgcttcatc
     5461 gtggggggca gggcccgggc gtgggaccag ggggaccggg accaggggga ctgggccggg
     5521 atggtcacct gtggactctc ggcctcaccg gtgccgctgt tgcgggccgg ctcggtctgc
     5581 gctaccgccg cggtggcggt cgtggtgatc agtccgagcg ccgtgcacag cgcgaggaag
     5641 gcggtgacga tgacggtcca cagctgcttg acctggttcc gggccatgat cccctcactt
     5701 tcgggttggg cgatttgcgt actttcctca tgatgtgtat gggggtcgcg aagtggggga
     5761 ccgacgctcg tggcgcgtcg atgttccgat gaacaccact cggatggacg tacaggccca
     5821 agagagccgc cgatggaggg gtcctgagca gggccggagg gatttggtcc ccttctacgg
     5881 cggtgaggag aggggcagtt ggagctcgga tcccaggtca ccgttggata tcggccggtg
     5941 tgtatagtcg ggcgccagag gtcccctacg tcaaggaaag acgaggtcgc gcggtgaaga
     6001 agcttctcct ggtcgcactg gccgccatcg gcgggctcct cgtgtaccgc cagatccagg
     6061 cggatcgcgc cgagcaggat ctgtggacgg aggcgactga ctccgtgccc acgggttcgt
     6121 gagtaccgac accagaatct gaaacaggcc ccgaccgccg cagcggtcgg ggttttgtgc
     6181 agcttcggcc gggacgaggg ggtgcgcgtc gtggggcggt acagggcgaa cgcggtggtg
     6241 cgcgggggcg tggcggccgc ggtggcggga gcgctggtgg ccggagtccc ggcgtcggcg
     6301 ggcgcggcgg gtcccggcgg gtacggcttc gatccggccg gccgccggct gagcgccgcg
     6361 acgaccacct ccgccgccgg gctcctcgaa cccggcggga cctaccgctc ctcactgccg
     6421 accgagggca ggacgtacta ccgcctcgcc ctggacgcca cgtccaccgc gtacgtcgcc
     6481 gtcaccgccg tccccccgtc cggcgccgac gtcgccgtca ccgacggcat ccgggtcgcc
     6541 ctccaggacg ccgacgggca ctactgctcg accgacaccg cgagcgtcgg cgccgcgcgc
     6601 agcccgcggc cggtcacggc gtgggggacg cgtgaggcgg gcaacggcag gcctgcctgt
     6661 caggacgcgg gcacgtacta cgtcgtcgtc gagcgtctgc gctcgtcttc ctcctcttcc
     6721 tcctcatctc ccttttcctc ttccgcctgg gagctggagc tgaccgccgc cgtcgaggcg
     6781 ccgctgaagg aggccggtcc gacgaccgcg cccgggacgg aggcctccgc ctcgactccg
     6841 cccctggcgg ggccggcccg gaaacggccg ggcgggaacg gcttcgccgg ggcggccgtc
     6901 gtcggccagg gcgtctggag cgacaccctc accaccggcc ggaccctctt ctacaaggtg
     6961 cccgtcgact ggggacagcg gctctccgtc accgccgagc tgggcagcgc gcccgacgac
     7021 gcgagcgggc tggtcgccgg agcgctgggt ctctccctct acaacccggc gcgcgtcccg
     7081 gtcgacgacg ccacggtctc ctacggcggc agccagaagt ccgccgcgct ggacgacctg
     7141 ccgccggtgc ggtaccgcaa ccgctacgcc gtccacgacg aggtgagcgg catgcgcttc
     7201 gccggcacct actacctcgc cgtccatctg tccgagcggg tcgccgagcg gttcggcgcc
     7261 ggcccgttcg acctgaccct gcgcgtgcgg gtcgcgggcg cggagcggca gccggggccc
     7321 gggtacgccg gggagtccac ccccgccgac accttccggg tcaccgacga ggagcgccgg
     7381 gccgccgcgc tcgggggcgg cggcttcgcg ggcggcgtga cgggcgggtc ctcgggcggg
     7441 gcggacgcgg gtgggggtac ggcgatgaag gcgctcgccg cgggcgggat cggcgccggg
     7501 accctgctgc tggcggtgct cggcgggtgg acgctcgtgg cccggcgccg ggccggctcc
     7561 gcggcggctc agacccgggt cagcgcccag aacccgacgg cgtagcaggc cagcgcgagc
     7621 agcagcagcg gcaccgcgat accggcgggc ggccccggcc ggcgcctgcg ggcgtgcgcg
     7681 gcccggggcg tctgcgcggg cggatcctga ggtgtgccgg gcgtgccgac tgggccgggc
     7741 gtggggggtg cctggagcgg cgcgggcggc acgtacgggt tcggggccgt gtacgtcgcc
     7801 gtggaggcgc cgtaggtggg gtggccgccg tacgcgggat gggcgccgta agggggtgcc
     7861 ggtggggcgg acggcggccg aggggtgggg gtcggcgtgg gcggcggggt cggggccggc
     7921 ggaggcgcgg gcgcggatgg ggacggggtc ggggaggcgg ggtccgcggc ggccccctgg
     7981 ggcgcgatgc gctgcacgtc ggtcggccct gtcccgtcgc tccgcgcgcc gcgggccgca
     8041 ttctccggtc cgtccgggcc gtagccctgc ggtaacgggc cgatctggtc gaagatctcg
     8101 atcagttcgt cgtcggggcc cggctccggg aggagttcga cggccgcggc gagggccttg
     8161 cgcgcgcccg tcgccgtacg gaagcgggcc gccgggtcgg gctggagcag ggtggccacg
     8221 acctgccaga gcggctcggg tatgcccttg ggggcgcccg gggtgccgtg gtcggcgaag
     8281 tactggatga gggccttggc gtccgggcgg gcgccctcca gcaggtacag ggcgaccagg
     8341 ccgaccgcga acaggtcggc cgggaagtcc ggttcggcgc ccagcagctg ctcgggggcg
     8401 aggtaacccg gcgtccccac cacgaggttg gtctcggtca ggcgcggttc gcccagccgc
     8461 atggcgatgc cgaagtcgga gagccgcagc cgggggcggc gggttccggt ggcttccagc
     8521 agcacgttgg cgggcttgat gtcgcggtgg acgacgccct cggcgtgtac ggcggccagg
     8581 cccgccagca gctggtcgag gagcgtgcag acgaagagcg ggggcaacgg gccgtagtcg
     8641 ccgacgagat ggaccagtga gccgccggtg acgaggtcca tggtgaacag gaccttgtcg
     8701 tcgtcggcgg cccagctggc gggggcgagc acgtgcgggt ggtcgatgcg cagggcctgc
     8761 tcgcggacga agcgcagcaa ggagtgcgcg tcgctctgct ggaggacctt ggcggccacg
     8821 taccggcggc ggcggtggtc ccaggcgcgc cagacggcgc cgacgccgcc gcgtccgatc
     8881 gggtcgacca gttcgtaccg gccggcgaac acctcaccca tcgctgtgcg ctgctcctcc
     8941 ccctgcgaca gccgccggcc ccccggccgg cggccccggt tcagctctgg tgggactggt
     9001 agtgcgccac cgcgtcggag gtgcggccgg cgccgtacac ccggaggaac tcggcgagtt
     9061 cggggtgggt cggggccagg gtgtccgcgg cctggaggat gtcaccggcg gcggccaccg
     9121 accgcagcag cgactggatc tcgcggacca cccgcttgac cgtgggcgcg cccgagctgt
     9181 tcgtcgtgtg ggtggtgttg ctgagcaccg agccgccctg cgaccgcttg atctcgtcca
     9241 tccgctcggt ggcctcggcc gcgctcacgc tgccgtccgc gacctgtgcc gccagctcct
     9301 ggagcagctg cacccgctgc accaccgccg gattgccgat cttggcccgc tgaccgctca
     9361 tcagctggga cagcatcggt gccgacagtc ccagtacccc cgccagacgc gcctggttga
     9421 gccccaggtc gtcgatgagc ttacggaaga gcgcccccaa cggctccccg taccagttcc
     9481 gctgcagttc ccgcgctctc gcggtcgctt cctgctgtgc ggcgtccatt gcgtctcccc
     9541 atcgcttccc caaaaaccgt ggcttcgctg tagcgaacca cgccgtgcat cttacggagc
     9601 gtggtcgtgt gcggggaccc ccaatctttt tgtgagatac ggggggcgac cgggtagtct
     9661 ggtccgaggc agccgccggg acagggttct tcccggcgga cacttgcctt ccggggcctt
     9721 agctcagttg gtagagcgcc gtctttgcat ggcggatgtc aggggttcga ctcccctagg
     9781 ctccacaccc cttgaacgcc ctctgacctg tggaaaacgg gttcaggggg cgtttttgct
     9841 gcctcctgat accttcacca aggaagaaac atcctcaaag aagaggcttc gggtgccggg
     9901 tcgtctgtgg cgggcggacg tcaccacgtg agggcgtcgt ccaggtcctg ctgccagtac
     9961 gtgacgcgga gcgagtcgtc gacgaagacg ccctgcgcgg gcagcggcgg ggtcgccgcc
    10021 gcaccgacgc tgccggagcc cgacggtccg tagaagtgga cgctcaggga cttctccgtg
    10081 tgcccgtggg cgccgctgcc gtcggcggcg gacagcagca cggccgcgta accggactcg
    10141 cccggcgcga gcgtgacgac ggcctgcggg tgggactcct cgacgaccgg cggtacggcc
    10201 tgcgcctcgc cgaagcggac ggccgggtag gcgtagaggt ggcaggggct ggatcccgtg
    10261 ttggtgaccg tgaggagcat gtggttcacg ggccggttca gcggggcggc gaccgtcttg
    10321 agggtggagc cctcgcacgt gacgggcttg cccgcggagg ccgggggctt ggccgggttc
    10381 ttggccgcgg gctcggacgg gtgctgtgcc gtgggcttcg aggcgggcgc ggaggcggag
    10441 gagccggtgc ccgtgccggt gccggtgccg gacgacgagg gcgcggtcgg ggccgacgtg
    10501 gtcggggcgg tcggcgtcgg cctggaggcg ctcggggcgg cgccctcgtc ggtgacgccc
    10561 gtgccgtcgc cgttgcacgc ggtcagggtc agcgcggcga gggcgacgct cgcggcggcg
    10621 gtgagaagtc gggtgcggga gttccggatc gtggacatga agtcgagccc tttcggtgtt
    10681 ccgttgctgg gaatgcttgg atgaccggag cttgtgacgt gatccgtccc agccgccaca
    10741 gccggccggc aatcagggat gctggaacgc tgaaacaggc tctgaccagg ggaaatgacc
    10801 gtcccctgga acgccggact gggacgcggg gggatggagg acatggtgtc cgggggcttg
    10861 gaggacgggt tcgccgcgct gctgcgggag ttgaaggacc gttcgggact cagctacggg
    10921 gcgctcgcca agcggctgca catgagcacg tcgacgctgc accggtactg caacggcgcc
    10981 gccgtaccga acgagtacgc accggtcgaa cgcctcgccc gggtgtgccg ggcgacgccc
    11041 gaggagctgg tggaactgca ccgccgctgg gtgctcgcgg acgcggcacg ggggcggggc
    11101 gcggaacgga ccgagccgag ccggccgccg gcgccgaccg ggactccggt cccgccccag
    11161 cccccggcca ctccagagcc agtggccccg gcctcggacc ctgccccgga cacccccgtt
    11221 gtcgagacga ccccgtctcc cgcgtccccg ccccggcgtc gtcgtcccgt ctggctcgcc
    11281 gccgcctccg cggtcgtcgt gctgggtgcc gtaggactgg ccctgcaccc gttcgccgga
    11341 ccgggccggg gcgatgacgg tgaccggcag gcggccggcg ccacagccgg tgccgccccc
    11401 ggttcccccg ccggtggcgc cggtacggcc ggatcccgga cgccgtcgcc gtccgccacc
    11461 ccctcgccgt ccccgtcggc cggcggcacg agccgcgggc cgtccgcccg gccctccgcc
    11521 tccgccgccg cctcggcccc cgcctccccc tccgccggaa gcgcggggga caccaccgcc
    11581 gtaccgctcg ccgtcggcgt gcgcccctac gtctacgtca gcccctgcag ccagcacttc
    11641 ctcgtcgaca gcgagcccca gcaggtcggt ccgcccgccg gcgagcagga cgccaggcgc
    11701 tttgccgacg cgtacggcgc ggtctcctcc gatgagcagc ggatcgccgt gaccgtgcag
    11761 ggcaccggga aggacaccgt cgtgctgcag gccctccatg tgcgggtcgt cgccaagggc
    11821 gcgccgctcg cctggaacga ctactcgatg ggcgtcggct gcggcggcga cgtccagacc
    11881 gagtccttcg acatcgacct cgacagcggc agccccacgg tcgccgtcgg gagcgcccgc
    11941 cgggacttcc cctacaaggt cagcgaatcc gaccccgagg tcttctacat caccgcccgc
    12001 accagggcgc acgacgtgcg ctgggaactc gctctcgact ggtccagcgg cccccgccac
    12061 ggcacgatcc gcatcgacaa ccggggtgtc ccgttccgta cgagcgccgg tgccggcagg
    12121 ccgggttacg actatccgct gggcggcggc gaatggatcc cccgcgtgca gtgacaccgc
    12181 tcacagccag cgtcaagatc acttaatgtc cttggtactc gctgggctgg aacggttccc
    12241 cccgctactt ttgaggctgc cgcttctggc ccggcggtgc gccggaatgc ggtgtcttcg
    12301 gtgtaactgc cccgttcgtt gcggggggca cgtaggaggg ggaccagtgc cttatccggc
    12361 tgcagcgcag tttctgcgaa cagcgattcc cgacatcatc cgcgcctatc agagcgcact
    12421 cagggccgtc cgcagtccgc tggccacacg caaggaagcg tggccgaagt gccgggacca
    12481 ggcgcaggcg atcgtcgagg actgtgtgat cgccctgacc ggcaagcaac cgccggcgcc
    12541 cgccgaggcc cggcgctatt cgcatctcgt cggcgtcgac cgggccacgc aagggatcgc
    12601 cgtggcggaa tccgtccgcg cggtcgacat cctgtggagc gcgatgcaac ccgccgtccg
    12661 cagcgcggtg caatgcgaag cggcggcccg gcggactgcc gcgctcctgc tgatcagcac
    12721 ggtattccgg gcgagttcgg gaagccggct ctacgccggt gccgtcggct acggcgacgc
    12781 cgtgccccgg ctgtccgagg acgttgcgga cgagaacgcc ggtgccgagg ccacgggcga
    12841 gacgccggtg gagtcgccgg cctgcgcggg gctgtcgcag cgcgagaagc aggtgctgga
    12901 gcgggtcgcg cgggcgatga ccaacagtca gatagcgcgg gacctcggca tcgagacggc
    12961 gaccgtgaag cggcacctga acaacatcta cgccaagctc caggcggact cccggatcga
    13021 cgccatcaac aaggcctacg gccggcgctg agtcaccggc cgggggcgcc gtcgtgcacc
    13081 gcgcggcgcc ccctcggccc ggctcaggcc ggccagcggt ccagcagcag cacggccacc
    13141 atcaccaggt tcgccgtgta ctgggtgcgc atgaaggcgc ggtaggcgct gcgccgggtg
    13201 cgcttgtcgg cgttgtcgac gcgggccgtg cggacgatct gcgtcaccac gcacaccgcg
    13261 cccaccgcca ccgggaccat cgcgacgagg atcgactgcg cccacagcag cgccgccagg
    13321 accgcggccg taccgacgct gagtgccccc gccgcaccca gcgcccgtgc cggccgtgcc
    13381 ccgtaccgca ccgcgacggt acggcggccg ccggtggcgt ccccgtccac atcgctcagg
    13441 tccttgacca ccgagcccac catcgccatc cacgcgctca tcacggtggc gaacaccagc
    13501 cccgccgtgt ccagttcacc tccggcggtc gcggcgccgc ccgcgaacga cgtccagccg
    13561 aggccgaaca ccaccagcgc gcacgcggtg ctccagcgct tcgccgggaa aggcggcgcg
    13621 gaatagatcc agccgagcag caggaaagcg gcgatccaga gggtgaggcc ggggacgaat
    13681 tgtgccagcg cgagagcgcc cagtgccgtg cccgccgtga tgaatgccgc gggtctttcc
    13741 ggcagatctc cccgcgcgat cggacggacg gaaccgttcg cgcggtcctc cttgacgtcc
    13801 atcacgccat tgatgagata ggcggcgatc acggcgagcc accaggcgag ggttccggcg
    13861 gccaactggg ccgggctcgc gccgtgctgg cgggtggaga atgcggcgcc cagtgcgtac
    13921 cgcagaagaa agacgatctg aacagtaggt cgcgcctcga tcagggaaag acgtgcataa
    13981 cgaaagatga agtgaggctg cgccttggga atgcgtattc cgttcgttat ctcggccacg
    14041 gccgtcacat tacgaggccg cccggcgccc ggcggggcct ctgcacccta gggtgcatcc
    14101 cccgcaatac ctcccccggt cctcctgtgg tcctttgggt gcagtggggc cgccacagcc
    14161 ccggtcccgc ccctcgcggc cgtaaccatg acggcatggc aaccggcgaa gacccaaggg
    14221 gaggtgggcc atggtggacg tgatcgtcgc gggcggcggc ccggtcggac tgatgctggc
    14281 gtgcgagctg cggctggccg gagtggacgt gctggtgctg gaccggctcg ccgagcgcgt
    14341 accgcactcc aaggcgctcg gcatgcacgc gcggaccctg gaggtgctgg accagcgggg
    14401 cctcgtggac cgcttcctgg agggccacaa gcgggcgccg gccacgcact tcgccgggct
    14461 gcggccgctg gagttcgacg cgtccgacac ccggcacccg tacatgctgc tcatcccgca
    14521 ggcgcacacc gagcggctgc tcgccgagcg ggccgccgag ctgggcgtgc ggatccggta
    14581 cggcaccgag gtcaccggcc tcgcccagga cgccgacggc gtcgacgtcg aggtcgcggg
    14641 aggtgagcgg ctgcgggcgc ggttcctggc cggctgcgac ggcagccgca gcaccgtgcg
    14701 ccgggtgctc ggcgtgggct tccccggcac gccggccacg gtcacggcga tgatcgccga
    14761 cgtgtccctg gacgagcccc cggcccagcc gaggctgctg gcccgcttcc cgggcgggca
    14821 ggccggggtg ctggagtacg cgccgggccg gtaccgggcg atgaccatcc agtacgacac
    14881 cccgtacgac ccggtggccg acggggacaa cccggtgacc ttcgaggagt tccgggaggt
    14941 cttccgggcc atcgccggca ccgaccacgg catgcgggac ccgctgtggg tctcccggtt
    15001 cggcgacgcg gcccggcagg ccgaccgcta ccgggtcggc cgggtcttcc tggcgggcga
    15061 cgccgcgcac atccacaacc cgtccggcgg gcagggcctg aacctcggca tgcaggacgc
    15121 ggtcaacctc ggctggaagc tggccgcggt ggtgcgcggg caggccccgc aggagctgct
    15181 ggacacgtac cacgacgagc ggcacccgat cggtgcgcgc gtcctgcaga acacgcacgc
    15241 gcaggtcgcg ctgagccggc ccgggcacgc ggtggacgcg ctgcgcgagc tgttcgccga
    15301 gctgatccgc atcgacgagg tgaacgaccg gctcacccgc atgatcagcg ccctcgacgt
    15361 gcgctacccg gtcgccggcg cccacccgct gaccggggcg cgcatgccgg acgtggacct
    15421 caagacggcc gacggtgaca cgcgcctgta ccccctgctg cactccggcc ggggcgtgct
    15481 gctcgacctc gccgacgacg cggcgctgcg tacgaccgcc cgcggctggg ccgaccgcgt
    15541 cgacctggtg ccggcgcacg gcgcggaccc gcggctggac ggggtggcgg cggtgctggt
    15601 gcggcccgac ggccatgtgg cctgggcggc cccgaccgac gtgaccttgc cggacgcgct
    15661 gacgacctgg ttcggcccgg cgcgcggggc gcggtgatgg ctccggtccc cgaaggctgc
    15721 ctcatggacc cgtccccgga ggccacctca tgagcctcat ccccgagagc cacctggacc
    15781 tgctccggcg gcccctgttc gtccacctgg cgacggtccg tcccgacggc ggtccgcagg
    15841 tgaacccgat gtggtgctcc tgggacggca cgcacctgcg cttcaccagc accaggaccc
    15901 gcttcaagtt ccgcaacgtg acggccgatc cgcgggtcgc ggtgtccgtg cacgaccccg
    15961 acgagccgta ccgctatctg gagatccgcg gggtcgtcga gcggatcgac gacgactcct
    16021 ccggcgcgtt cttcttccga ctggccgagc ggtacggccg ggagctgggc gggcggctgc
    16081 cgccggacgt gcgggagcgg gtggtgtacg tggtccggcc gacggccgtc agccaccagt
    16141 gacgagcccg gccagcacct cgtccaccgt ccgtacggcg gccccggctc ccgccaactc
    16201 gccgaggacc gcgtcctgtt ccgcggccgt gaccgtggcc gtggcgtcgg agacgacggt
    16261 gaccgcgagg cccgaggcga gcgccgtccg ggcggtggcg gcgacgccgt gggccgtgga
    16321 caggccggcg agcaccaccc cggtgacgcc gctcgcggcg agatgcgcgg cgaggccggt
    16381 gccctcgaag gcgtcgaggc cgtgtttggt gaccagcagg tcgtccgggc cgggcgcgca
    16441 ccgctcgtgc agctggttgg ccggcgcgtc cggtccgccg tcggcgccgt cggcccgcag
    16501 atagcgcacg tggatcacag gggcgaaagc cgcgcggagc cgggcgcagg cgtcgacgac
    16561 gtcggacgcc ggccggggct gccaggcgtg catttccaga atccagtgct gcaggtcgat
    16621 gagtatcagc gcggtgcgtg agtccgcagt gaactgtgcg tccgtcatgg gcccggacgg
    16681 tagcagaaac acgtccggaa tcggccactg cacccttggg tgcagttccg ttccgggccc
    16741 ccggaagtcc ccctacggta gttctcgcgg tcgacgaaaa cgcgtaccga acccggaagg
    16801 aaaagaacac gtatgaagct cagggcggat cgtctggaac ggctcgggaa ttacttttcc
    16861 cggctgacgg acgagggaaa gattcccggc tggtcggcca tggtctcgca gcacggagag
    16921 acggtccacg aatcgtcggg cggaatggcg aacatcgccg ccggaatacc gatgacggcg
    16981 gacagcattt tccgcacctg gtcgctgagc aagccgatga cctcggtggc gttcatgcgg
    17041 ctcgtcgagg agggcctcgt cggcctgaac gacccggtgg cggactacct gccggccttc
    17101 cgcgaccagc gggtctaccg tgccggactg ccggcggccc cgatcaccga gggcctggtc
    17161 gagccgatgc ggatgtggca cctgctgacc cacaccgcgg gcctcggcta cggcgcccac
    17221 cagtcgcacg ccgtggacac gctgtacgtc aacgacggct acacggtgga gcccccggcc
    17281 ggcaccggcc tggccgaggc cgtcgagaag tgggcggcct tcccgctgcg cttccagccc
    17341 ggcaccgcct ggaactacgg cgtgagcacg gacgtcctcg gccgggtcat cgaggtggtg
    17401 tccggcaagc gcctcgacga gtacatgcgg gagtcgttct tcgagccgct cggcctgaag
    17461 gactccggct tttgggtgga ggcgcgcaac aaggaccggt acgccgagat ctacaccccc
    17521 accgccgacg gcggcatcga gcacaacccg gccgccagcg cgtacccgac cgaggcgccg
    17581 ctgttcctgt cgggcggcgg cggcatctac accacggtcg ccgactacat gaagttcctg
    17641 aacatgctgg cgaacggcgg ccgcgtcggg cacggctccg accactacct gtccccgctg
    17701 acggtggagt cgatccgcag caaccacctg ccgcggaacg tcaccctcgg ctccggcttc
    17761 ggcagctggg gggtgcccgc ggtcaacgag ctgatgccgg cggccgggtt cggactgggc
    17821 ttcatgaccg tccagcagcc gcaggaggcg catctgctga cgcgggaggg cgagttcttc
    17881 tggctctcca tgagcagcgc caacttcttc gtcgaccccg cgtccggcgt ctgcgccctg
    17941 gtctcgcccc agctgtaccc ctcccgcacc ctcccgatca ccaaccgcct gcggcagttc
    18001 gtctaccagg cctattgctg acccgaggtg agccgatgac tacgagcacc atgccgatgc
    18061 cggtcgaggt ctcgctcaga tggggcgacg tggactccta cggccacgtc aacaactgcg
    18121 agatcgtacg gattatcgag gaagcccgga tgcggtggct catgtcgagc ggcgtgttcg
    18181 acggggagac cgcggtggtc gcggcccatg agatcggata tctgcgaccg ctccggtact
    18241 cgctcgaccc ggtcgatgtc gaggtgtgga catcgaatgt ccggcggtcc agcttcgagt
    18301 tcaacttcag gatcctgaac agcgaccggc aggtgagcgt caaggccgtc agccggatgg
    18361 tgatgttcga cctggaaaag caggagagct acgccatcgg cccgcgcctg cgcggatttc
    18421 tgaccgcggc ctgcggcgaa cgcctctgat gcctgccggt gaattccccg gcccttccct
    18481 tccccccctt ccgagcgaga aagtcgaagg aatcctccat gtcgaccgtg gtttcgaaag
    18541 cacccccacg cgaagcgcaa tcgaccatgg gcacgctggg gctgaccatc gtcctggtca
    18601 ccgcggcgct gacgatgatc gacgcggcca tcgtcaacgt ggccctgccg tcgatccagg
    18661 ccaccctgca caccgacgcc tcggtgtcgc agttcgtggt cagcggctat gtcatcgcct
    18721 acgccatcct gctggtcctg ggcggcaagc tcggtgaccg ccacggccgc cggcgcctgc
    18781 tccagatcgg cgtcctggcc ttcacgctga cctcgctggc ctgcgggctc gcccccagca
    18841 tcgagttcct gatcgtcgcc cgggccctgc agggcgcctc ggccgcgttc ctgctgccgc
    18901 aggcgctgtc gacgatccag acgtccctgg cggagtcggc caagacccgg gccatcggcc
    18961 tgtacggcgc gatcggcggc ctgtcggccg cggccgggca gctgctcggc ggcgtcctgg
    19021 tctgggcgga catcgcgggc ctggactggc ggcccatctt cctggtgaac gtgccgctgg
    19081 gcatcctggc gctgatcggc gcgcagaccc acgtccccga caccaaggcg gccggcgggc
    19141 agtccatgga cgtcggcggc acggtgctgc tgggcgttgc ggtgctcgcg ctgctcatcc
    19201 cgctcagcgt cgggcggcag gcccactggg cgctgtggtg ctggctgctg atcgcggtcg
    19261 cggtggtcgc cggggtggcg ctgtggcgct acgagcgccg gctggagcag cagggccgca
    19321 ccccgctgat cccgccctcg ctggtgcgga tgcgtccggt caaccgcggt ctgctcatcc
    19381 tcggtggcgg gttcctggtc ttcagcggct tctccttcgc ggtgccgctg gcgctgcagg
    19441 acggcaacgg catgagcgcg gtggagtcgg gtctgtcggt ggccccgctg gcggtgggcg
    19501 ccttcctcgg ttcgctgcgc gccccgaagc tcatggcgaa ggtcggcatg cgcaccgtgc
    19561 aggtcggcgc ggtcgtccag atcgccggtc tggcgctgct gatcgcggcg gcccggctgt
    19621 ggtggccgca catccgcttc tacgagctgg tcgtcgcgat gttcctggtc ggcgtcggca
    19681 acgggctgtt catcccgccg gtgttccgca cgatcctgtc ctccctgccg ccggaccagg
    19741 caggcgccgg cagcggcatc atgtcgacca cccagcagac ctcggtcgcc gtcggtacgg
    19801 cggtgctcgg ccaggtgttc atcaccttcg cctcgggcgg cgacatgaac ctgggcttcg
    19861 tcgcggtgac cgcgacctac ctcgtggtcg gcgtgctgat ctgcctcttc ggcggcgcgg
    19921 ccctcaccca gaagaccggc gactgaccgg tccctccttc accccctagg ccccacggcc
    19981 aacggcagga agagacagcc atgttgatag gcgacctgta tctcaacggg tgcgcggtgt
    20041 cctacccgac gacgcgcgtc cccgtgagcg aggccctggc gcggggcctg atccgcgacg
    20101 ccgacgagac cctcggcgac ccggcggtgc ccgtcttcga ggagagcgcc ccggccgccg
    20161 acctcgccgt cgacgccctg cgccggtcgc tgaagtcgac cggcacggac gcggccgacg
    20221 tggacgtgct gatccagtgc gggtggtggc accagggcta cgacatctgg agcgcggcgc
    20281 actacgtcgc gcaccaggtc ggggcgctgg gcgccgtacc gatgaacctc tcgcagggct
    20341 gcaacgcccc catggcggcg ctcgaactga ccgtgcgggc gatgcgggcc gactccgcga
    20401 tccgggtcgg tgccgtcacg acggccgacg ccatgcggtt cccgcaggtg gaccgctgga
    20461 acctcaacta cggctgtgtg cacggcgacg cgggcaccgc gtggctggtg gcgcgcgagc
    20521 cggccggacc gcacgccttc cgcgtcctgt cggtcgccag caaggcggcg cccgagctgg
    20581 agatgatgaa ccgcgccggg ctcgccccga cccccggccc cgcgctgcgc gagggcggca
    20641 cggtcgacct gaaggcggcc aagaaggcgt acctcaccga gttcggcatg gacggcttca
    20701 tcggccgctc ccgcgactgc ctgaccggca gcgtgcgcca ggcgctggac gaggccgggc
    20761 tggacggcag cgagcgccgt atccgggcgg tgtcggtgcc ccggctcagc ggcaagatct
    20821 tcgagaccgt ctaccgggcg cagctcgccc ccttcttcgg cgaggacaag ctgcgctggt
    20881 ggggcgaccg cacggcacac ctcggggtcg ccgacgtcgg cgccaacatc gaggacaccg
    20941 ccgccgaact gcccctggag cccggcgaca tcaccgtcgt ggtgaacgcg ggcggcggct
    21001 acacgtggtc ctgcctggtc ctggagcacg ccgcctgagc cggcccgcac agggccccac
    21061 gtaccacccc tccctcccca tcaccgtaat cactcggaat cactcgaaac aacccaagga
    21121 gacagcatca tgacgatcac ccaggtgtct gacgagaccg tccgtaccac caccctcgac
    21181 atcatcgtcg acgagctgga gctggacgtc gaaccggagg aggtcgacct caaggccgac
    21241 ctgatcgagg tgtacggcgc cgactcgctc ggcctgatac aggtcctcgc ccgcgtcaac
    21301 aagcagctcg gcatccgcgt gccccgcgag aaggccgtcg acctgcgcac ggtcgagctg
    21361 ctgatccagc agatcctcga catccgcgac ggcaaggacg gcgaccagtg acgcgcgcac
    21421 gccgggtcgt ggtgaccggc ctcggctgcg tgagcagcat cggcaccggg gtccaggagt
    21481 tcaccgaggg catcaaggcc ggtctgagcg gcatctccga gatcacgtcc ttcgacagcg
    21541 gcgacttccc ggcccggctg gccggtgagg tgcaggggtt cgaccccgcc gggatcgtcc
    21601 ggaacatcga cgtcgagcag tggggccgta ccgcgcactt cgcggccgcg gccgcccggc
    21661 tggcgctgga cgactccggt ctcgaactgg acgaggagag ccgggcgacg gcgggcgcga
    21721 tcatcggcac caccaacggg gaggcgccct ccgtcgacac cctgacccag cagtggctgg
    21781 acggcggccc gagcacgctc tccgccgacc tggtccgcaa ggtcccggcc ggcaacatcg
    21841 ccgccgcggc cgccgaggaa ctgggcctgt acggcgagac cgtcgtcatc ccgacggcgt
    21901 gctcggccgc caactacgcc atcggcagcg ccgccgacaa gatcatcgcc ggtgaggcgg
    21961 acgtgatggt ggccggcggc gcggacagcg tgaaccggtt cacgcacgcc gggttcctca
    22021 gcctcggcgc ggtggccgac ggggtgcccc ggccgttcga ccaggaccgt tcgggcatcg
    22081 tcaccgccga gggcggcgcg gtgctggtcc tggaggagct ggagcacgcc cgggcgcgcg
    22141 gcgcgcacat ctacgccgag ctgctcggct acgggctcag ctgcgacgcc caccacatcg
    22201 tgcacccgga cgccgagtcc atcgcgacct gcatccgccg ggcgcacacc aactcgggca
    22261 tcgtcgccga ggacgtggac tacatctgcg cccacggcac cggcacgccg accaacgaca
    22321 tcaccgaggt caccgcgacc cggctggtgt tcggcgacga gcacccgccg atgagctcca
    22381 tcaagtcgat gctcgggcac accatgggcg cggccagcgg cttcggcgcg atcgcctgct
    22441 gcaaggcgat cgaggacgcc ttcctgccgc ccaccatcaa cctgcgcacc gtcgacccgg
    22501 ccttcggcga gggcatcgac ttcgtcggcg gcggggcgaa ggcggccgcg gtgcgggtgg
    22561 cgcagaacca cggcttcgcg ttcggcggca acaacgccat caccattttc ggcgcctatg
    22621 ccgaccgcga gccggtcggc gcgggggagg gaccgcgatg accgtcacgc agcagccgta
    22681 cgacaccggg cagccggccg gcaccgggga actgcggatc tccggggtgt ccgtgctgtc
    22741 cgcggccggc gtcggcctgg acgccctgcg cgaccggctg cgcggcccgg agccggtcct
    22801 gggcggcgac gagccgtgcg cctcggacgc cgccgactac gcgggcctgc ccggccgggt
    22861 cgcggcggtg cccgacttca agatcaccga ctatgtgccg cgcaagggca cgaagaacct
    22921 ggaccgcacc acccgtctcg gcctcgccgc cagcaccctg ctcaagcggg aactgagcga
    22981 gcggaccgag atccccgagg cgtcctggga ggccaccggg atcgccatgg gcacggtcgt
    23041 gggcagcctg cgcagcagcg tcgaactgga cgtcgacatc ctccagggcc agggcaccga
    23101 cctggtcaac ccggcggtct tccccaacac cacgatgaac tgctgcgcca gccagatcgc
    23161 catctggcac accttccgcg gccccaactc caccctggcc aacggcaccg tcagcgcgct
    23221 gtccgcgctg cggtacgcgg cccggctgat ccgctgcggg cacgccgggc ggatgctggt
    23281 cggcggcgtg gaggagctgt cgccgcacac cgcgtggggc acccggctga agaaggaggt
    23341 gcaggagtcg gtcccggtcg gcgagggcgc ggcgctggtc gcgctggagc ccgcgggacc
    23401 ggacgcgccg cccgcgctgg ccacggtgac ggcgtgcgag gtgctgttcg cccgggagcg
    23461 cacgcaggcc gggtacgccg aggcgctggg ccgtgccgtc gaccgggcgc ggcaggccgc
    23521 cgaggccgcc gggaccggcg tcgagctggt cctgcccggc actgtcggaa cgttcctgca
    23581 gggtgcggag gagtcggtcc tggaccggtt cgacgccgag cgcgtggacg tgcgggccgc
    23641 ggtcggcgag tgcggcggcg ccctgggcgc catgcagctc gccgccgcgg tggccctcgg
    23701 ccggcccggc acgggcgtgc tgatcaccgg catcgacgag tccggggcgg tggccgctgc
    23761 cgtgctcacc atcggggagc gcgcatgacc accgcgacca cggccaccgc ggccgacgtg
    23821 accgcgaccg cggggacccg ggtgcgccgg gacctcgtcc accgtgccca cgagcaggag
    23881 gtcctggtct ccccgccctg gcgggagccg gacggcggct acggcagcag gaccgtcacc
    23941 gccggcatca gcgactacta ccgcgaccac cccgtcccgc accggctgga cgccctgctg
    24001 ctgatcgagg cctgccgcca ggcggcgctc agcgcggcgc acgcgttcga gggcctgtcg
    24061 gagaacatcg cgttcttctt caactcgatc gacatggaga tcaccgatcc cgggcaattg
    24121 gcggcggccg acgaggagct gacgatccgt tcggagttcg agcggctccg gctgcgcggc
    24181 gacggctcgc cgaagcagat cacgtacacc cagtacggca ccgacacctc gggccggaaa
    24241 ctggtgcgga cgtcgatggc ggtgcagggc ctgcccaagg accgctaccc ggagctgcgg
    24301 gcctatcagc gcggcggctc ccccgcgccg acgaccgcgg cgctgcgctc cggccaggtg
    24361 cggcgcgccg acctcggcgc tccggccagt gtggcccgta cccgcgtcga gaacgtggcg
    24421 atcgccgggg tgcgggccga ggccggggtc cgcgtcgcgg acctcgcacc ggacctggcc
    24481 aacgccgccc tcttcgacca cgactacgac cacttcccgg cgatggtcct catcgaggcg
    24541 ggccgccagc tggcgctgtc cggcacggac cggccggccg ggcacgtggt gaccgcggtg
    24601 cgcgccgcct tcgagcactt cgcggagctg gacgcgccga tccggctgga ggcccggcag
    24661 ggcgagcgat gggtggacgt ggactgcgtc caggacggcc tggtcgtcac ccgcatggcg
    24721 ttcgctctct cgccggcccc cgcgggggag gcgtgatgcg gcccgcgatc tggaccgact
    24781 tccgcggggt gctcaccccg cccctgcggg aggggctgcg cgcctactgc gtgggcaagg
    24841 agttcacgcc cgcccagctc gggcagtgcc tgcgcgcgat cgccgaccgg tacggctgtc
    24901 ccgacgggat ggccgtgctg gactccggga tcctctcgga gcggcagtgg gcggcggaga
    24961 tcgagcggga gctggccggc cggttcggcc tcaccgccga cctctcccgc ctcggctccg
    25021 agtggtggag cgaccgccgg gtcgacagcg tgtggctggc cgcgctgcgc cggtggcggc
    25081 aggcgggcgc gttcgtcggg ctggtctcca acctgcccgt cgactggaag ccgtacttca
    25141 ccgccttcct ggactgggac gggctgttcg acgacgtcct gctgtcctgc gacaccgggg
    25201 cccgcaaacc cgacgcggcc ctgttccgcc tcgccgagtc ccgcaccggc ctgccgcccg
    25261 aggcccacgt cctcgtcgac gacctcgacg ccaacgtgac cggcgcgcgg cgggccggct
    25321 ggaccggtgt gaccggcggc ggtgagcaca cgccggccgc cgtcgagcgg atcgacgccc
    25381 tggtgggcgc cgccgcaccc cgaaaccacc ccccggtgcg catcggcgca ccccaccaag
    25441 gagcaggacg atgacgagtc gatcggtgtt cgtgacggga gccagccggg gcatcggcga
    25501 ggccatcgcg aaggaactga acaagcaggg ataccgcgtg gtgggcaccg cccgcaccac
    25561 ccgcccggag ctggagggcg tcgagttcgt cgcgtgcgac gtgcgcgacc cggagtccgt
    25621 gcgcacggcg gtcgagcagg cccgggagat cctcggcgag atcgacatcg tcgtgaactg
    25681 cgccggcatc atgaacgacg gcccgctgct cacccagacc caggagggcg tgcagagcgt
    25741 cctcgacacc aacctcaacg gctccatcaa cgtggtccgc gagaccgtgc cggacatgat
    25801 ggccaacaag tggggacgcc tggtgttcgt ctcctcgatc gtggcgctgt ggggctcgcc
    25861 gggccagacc aactactcgg cgtccaagag cggcctgatc ggccttgccc gctcgctggc
    25921 ctgggaactc ggccgcgccg ggatcacctc taacgtggtg ctgcccggcc tgatcgagac
    25981 cgacatgatc tccggtctga ccgagcggcg ccgcaaggag atcatctccc agacggccct
    26041 gcgccgcacc ggcacccccg aggaggtggc cgccctggtc gccttcctcg tctcggagga
    26101 ggccgggttc atcacgggcg cgtcgatccc gatcggcggc ggcgtcggca tgggactgtg
    26161 atgagtacga cgacctatcc cgtacggccc ggcgcgcgcc gtatgcccct ggtggccgtg
    26221 gacgacgtcc gggcggccgg caagggcttc gtcggccgca agacgatcga ccccggtgac
    26281 ccctatctgc gcggtcactt cccgtccctg acggtgtatc cgggggtgtt cctggtcgag
    26341 agcctccagc agatgctgga ggtgcacctg gacggggcgc tcggcggcgt cgagctggtg
    26401 gagctgggct cggtccggtt cagccggccg gcgctggccg gggacgaggt ggtcatcgag
    26461 gccgaggtcg acggcgaccg cgaccggctg gtcaccaagg ccacgtgcag cagcggcggg
    26521 cagcgcctcg cccgcatcac ggcgacctgg cggtgccggc catgacgacc acgacgtatc
    26581 ccgaccccgc cgacctgctg ccctacggcc accccgcgct ccaggtcgac cggatcgtgc
    26641 ggcacgagcc gggcgcgctg gaggccgtga aggccgtgac ctaccacgag ctggacgccc
    26701 acgtcggcga ctcccggccg ggccggttcc ccgccagcct caccctggag tcgttcctcc
    26761 aggcctgcgg gctgctgctg atgcgggaga cggccgacgc cggcccggac gcccgcccgc
    26821 tgctgatctt cggctcggcg cgcggggtcc gggtcaccgg cgccgcccga gccggtgaac
    26881 tgctcgtcca ctcggtggag ttggtcgacc gcgacgagga gacggccacc ttcacgggcg
    26941 tctcccgggc cggggacggc cgcacggtcg tggaggtcga ccgtgccatc accctgctgc
    27001 gcccggccgg ctcgctcgac ggcaccggcc gctgagcgcc cccttcttcc gcgtgccccc
    27061 tcgcgcacgc ccccaggcgc gctcctctta cgcgcgcgcc ccaacgtgcg cccctcttac
    27121 acgcgcgccc cccacacgtg acggaacgaa acggaggatt ccgtggtgca ccactttgtc
    27181 gtgaccgccc ccggccaggg cgtccagcgg ccggggatgc tcgacccctg gctggacgcc
    27241 gtccccgggg cccgggccct cgtcgacgac tggtcgcggg ccgccggcct ggacctggtc
    27301 gaggccggcc gggatgccgc gctgctcgcg gacacggccg tcgcccagcc gctgatcgtc
    27361 gccgcctcgc tgctcgcgca ccggctgctg cgcgagcggc tgccgctcgc cgccgacgag
    27421 gtgctgttcg cgggccactc ggtcggtgag ctggccgcgg cggccggtgc cggctacctc
    27481 agcccgcggg acgcggtggc cctcgcccgg gtgcgcggcg cggcgatgtc cgcggcgtgc
    27541 gcgctcgccc cgaccggcat ggccgcggtg atgccgggcc ggcgggcggg cgcctccgac
    27601 gaggagatcg tcgccgcggt cgccgcggcc gggctgacgg tggccaactt caacggcagc
    27661 caccagttcg tcgcggccgg cccggcggac cgcgtcgagg cgctcgccga ggagccgccg
    27721 cccggcaccc gggtcgcgcc gctcaacgtc gcgggcgcct tccacaccga ggcgatggcg
    27781 cccgcggtgg agacgttcgc ccgcgccatc gccggggtgc ggatcgcgcg gtccgcctcc
    27841 gcgatggtcg ccaacggcga cggcgccctg ctgaccggcc cggaggacct gcggcgccgg
    27901 ctgatcacgc agatcacctc gccggtccgc tgggacctgt gtacggagac gatcgcccgc
    27961 ctggcgccgg acgccctgca cctcgaactg gccccggccg gaccgctcac ccggctgctg
    28021 ggccgggccc ggcccgaggc gcgggccgtg gcgctggggc tgccggagga catcgaccgg
    28081 gcggtggccg aggccgccga gcgtcccctg gcgggcgcgc gatgaacacg ccggacggga
    28141 acgggcaggg acggacagga acggggagca ccgcatgcgc agcgccgtcg aggagctgac
    28201 cagcctcaaa cgcgagatca ccgagggccc ggacgccgcc gccacccggc ggcagcgcga
    28261 caagggcaag ctgaccgtgc gggagcgcat cgcactgctc ctggacgagg ggtcgttcca
    28321 cgaggttgag ccgctgcgcc ggcaccgcgc gcagggcttc ggcctggagc gccggcgccc
    28381 ccacaccgac ggtgtggtca ccggctgggg cacggtcgag ggccgtacgg tcttcgtcta
    28441 cgcgcacgac ttccgcatct tcggcggcgc cctcggcgag gcgcacgccg agaagatcca
    28501 caagatcatg gacatggcca tcgcggccgg ggcgccgctg gtgtcgctga acgacggcgc
    28561 gggcgcccgc atccaggagg gcgtcaccgc cctcgccggc tacggcggca tcttcacccg
    28621 caacacccgg gcgtccggag tgatcccgca gatcagcgtg atgctcggcc cgtgcgcggg
    28681 cggcgccgcc tacagcccgg cgctgaccga cttcgtgttc atggtccggg acacctcgca
    28741 gatgttcatc accggccccg acgtggtgaa ggcggtgacc ggcgaggaga tcagccagaa
    28801 cggcctcggc ggcgccgacg tccacgcgga gacctccggc gtgtgccact tcgcgtacga
    28861 cgacgaggag acctgcctcg ccgaggtgcg ctacctgctc tccctcctcc cgcagaacaa
    28921 ccgcgagcgt cccccggccg caccatccgg cgacccggcc gaccgccgct gcgaggaact
    28981 gctcgacctg gtcccggccg acggcaaccg gccgtacgac atgcgccggg tgatcgagtc
    29041 gctcgtcgac gacggggact acctggaggt gcacgagcgc tgggccacca acgtcctcgt
    29101 cgccctggcc cggctcgacg ggcaggtcgt cggcatcgtc gccaaccagc cgcagtcgct
    29161 ggccggcgtg ctggacatca acgcgtcgga gaaggccgcg cgtttcgtgc agatgtgcga
    29221 tgccttcaac atcccgatcg tgacgctcct cgacgtcccc ggcttcctgc cgggcgtcga
    29281 ccaggagcac ggcggcatca tccggcacgg cgcgaagctg ctctacgcct actgcaacgc
    29341 cacggtcccg cgcatccagc tgatcctgcg caaggcgtac ggcggtgcct acatcgtcat
    29401 ggactcccgc tcggtcggcg ccgacctgtc gtacgcctgg ccgacgaacg agatcgccgt
    29461 catgggcgcg gagggcgccg cgaacgtcat cttccgccgc cagatcgccg gcgccgacga
    29521 cccggaggcg atgcgggcac ggatggtcaa ggagtacaag gccgagctga tgcaccccta
    29581 ttacgccgcc gagcggggcc tggtcgacga cgtgatcgac cccgccgaga cccggcaggt
    29641 gctgatccgc tccctgcaca tgctgcggac caagcacgcc gacctgccct cccgcaagca
    29701 cggcaacccg ccccagtgaa cctgcctccc cctgaacgga gttgatcccg gtgacttccg
    29761 cgacccctct ggtccgcgtg gaacgcggcc atgcctccga cgacgaactc gccgccctca
    29821 ccgtcgtcct gctctcccgt acgaccgccc ccgcccccgc cgccgggccg accgccccgg
    29881 ccgtccccct gtgggaccgc ccggagcgca acgctcccta ccgcccgccg gtcagctggc
    29941 gccgctagcc gcgcggggag agggagggag acggacatgg acggtacgca ccacgggcgc
    30001 ccggcaccgg ccggcccgca ccgcacaccc cccgagcagc cgggaccccc gcgcgcgctg
    30061 ctcgccgggg aggaggaacg cggcgacgag ccgcacatcg agcgcggaat cgactgaccg
    30121 gcgatgacgg cccgacagca caccgacgtc ctgccccgcc cgtcccccgc caccgcgctg
    30181 atggcctccc tgctgcccgc gcgggcggtg gccgcggagg ccttcgggga cgggcacgac
    30241 gaggactggt tcgggcagct cctcccggcc gaggcgcggc tgatggcggg tgcgggggag
    30301 aaacggcgac gggacttcgc gggggtacgg gtgtgcgccc agcgcgcgct gcgcaccctc
    30361 gggcacgcac cggtgcccct gctgcccgga ccgcgcggcg agccccgctg gccggacggg
    30421 gtcgtcggct ccctgacgca ctgcgccggc taccgggcgg cggtggtcgc ccgccccgga
    30481 cccggcctgg ccggggtggg catcgacgcc gagccgcacg ccccgctgga cgccgacgtc
    30541 ctggagatgg tcgcgagccc cgccgagcgg gcccacctgg cgctgctcgc gcgcacccgg
    30601 ccgggggtgc actggggccg cctgctgttc tgcgtgaagg aggccgtctt caaggcgtgg
    30661 tacccggcgg cccgctgcga gctgggcttc ctggaagcgg acgtgagatt cacggcggac
    30721 ggcccgcaca gcgcggacgg caggtacggc accgacggca tgcacggcat cgtcacggcc
    30781 acgctgaccc gggcgggccc gttcgccacg gtctccggcc gctggcgggt cgccggggga
    30841 gtgatcgcga cggcggtcgt gatctgaccc ggcacgagag caacaccgac gatggaggaa
    30901 gaaaagaaat gcgtcttgcc gacagccccg gcgtggagtg cgcggcggag atcgccgccg
    30961 acccgcagcg cgtgtgggag ctggtctcgg acatcgccac ctcggcccgg cacagccccg
    31021 aactgcagga ggtggagtgg ctggacgggg ccgacgggcc ggcggtcggc gcgtgcttcg
    31081 ccggccgcaa ccgcaacagc ggactgggcg agtggcgcac ggtcagccgg atcacccgga
    31141 tgtcacggcc gcacgtcttt gagtgggagg tcgtccacta caacgaccgc cggcacggcg
    31201 agccgctcgc ggtgtggacg tacaccctgg aacccctcgc ggacggctcc ggcacgctcg
    31261 tgcggcacgg gatgcgcatc ggctccgccc gcggaccgct gcacgacgtg gtcgagctgc
    31321 acccggagcg ggaggagcag atcgtcaccg gccggctggc cctgctgcgc gccggcatcc
    31381 agacgacgct ggcaggcctc agggccgagg cggagggacg gctggtgtga accccggggg
    31441 accccggggg gtgtcctcag gcctgtgcgg cggcgcgccg gacggcgaag ttgcgggccg
    31501 agcgctcgtg cagggcgatg ccgacggaca ccgacacgtt cagggactcc gtggagctga
    31561 gcatcgggat ggacaccgtg cccgccgacg cctcctggaa caggcccgac gggccgccct
    31621 tctcgctgcc gaagaccagc gccatgcggt cggcgcggtc cccgaggtcc ttcaccccga
    31681 ggtcgccgtc ggcgtccagc accatcagcg cgatgtcgtt gtcccgcagg aaggagacgg
    31741 cctcctcgcg gtcggcgagg acgacgggca gggagaagac gtagccgcgg ctcgcccgca
    31801 gcagccgccg gtcggcgatg gtggcgaggt cgctgtcgac caggacgatg cccgcggcgc
    31861 cgagcgccag cgaggtccgc acgatggcgc cgatgttgcc gacgatcttc acaccgtcga
    31921 ggacgacgac gtcgccgccg cgctcggcga tgtccgccag ccgggccggc cgcggcacgc
    31981 gcgcgatgcc gaagaccttc gccttgcgct cggccttgaa caactggttc acgatcgaca
    32041 cgtcgatcag ccggaccggg atctcccgct gccggcacag gtcgagcagg gcggggtcga
    32101 gcggcgtacc gctggagccg tacacctcga tgaactgcac accggccctg atgcactcca
    32161 tcagcggctc ggtgtcctcg atcagcgtcg tcttgatgct ggcccgcgaa tgcttcgtga
    32221 cgtcgatgat tctctgcacc gcggggtcag aggcattcgt gatgatggcg ggctcagtca
    32281 tgcgcgcagt ctagtggccg ggagcctgcg cccccggcca ccagagcggc ggtgcggtgt
    32341 caggcctggt cgtcgcgctt ggccgcctcc tcggcggcct ccttggcctg gacctccggg
    32401 tccagtacgg cctcggcgct gccgtcgacc gaggtcagac ggcccgactc aggcacttcc
    32461 gtggcctccg gcggctcgac gagccagtcc gggttggcct gcttgtccca ccacttccat
    32521 gcggcgaacg ccccgcccgc gaccagaccc agcacggcca gcatccgcac ggcgcggccg
    32581 gtcctggccc gccgttcgtg cttgcggacc agcttctgga tgtcctcggc ggtcacctgg
    32641 ccgcgcaggg cgaccagagc ggcggcggca cgtgtggcgg cctcgtcacg gacgggtccg
    32701 gcggcggcca ccgcctgctc gatcatcggc cgggagtagt cggcggcctg ccgtgcggcc
    32761 ttgcgggtgc gcagggccgc ctcctgtgcg gcgagctcca ccttcggcgg cacatgggtg
    32821 cgggcctgct ccagccgggg cgcgagatgg gcgccgtact ggacgcgggc ctgttcggcg
    32881 gccagcgtca ccttgggcgc aagccgtacg cgtgcctcgt gcgcgtagtg cgcggccctc
    32941 tccttggccg tgtcggcgta gggcgccacc acttccgcgg cgtgcagcac gctgtccttc
    33001 gccgaaccgg tcgcggcgcg cacgctgtcg atgcgggtca cgggttcctc ctcctcggtg
    33061 gcgtacggta attcgacttt ccaccctttt gcggatcatg cctgcaccgg agccgcgggg
    33121 catgcgggga ggggcatacg ggtgcagacg ggtcatcaag gtgcttgtcg tcgacaatgc
    33181 cacggatcgg ccccgcgcgc ccccgtcccg ggccgactcg tccgcgcttt ccgccgaccg
    33241 cacgacggcg tgcgaggatc gggggatcac aggaggacaa cggaaggcac atcgtggccg
    33301 agcagctcta cgccactctg aggaccaacc acggcgacat ccggatccgg ctcttcccgc
    33361 accacgcgcc cgccacggtc cggaacttcg tcgagctggc gcagggggag cgggagtgga
    33421 cccaccccgc gaccggcgcg aagacgacgg ctccgctgta cgacggcacg gtcttccacc
    33481 gggtgatgag cggcttcatg atccagggcg gcgatccgct gggcaacggc accggcgatc
    33541 ccggctacca gttcaaggac gagttccacc ccgacctgcg cttcgaccgg ccgtacctgc
    33601 tggccatggc caacgccggg ccggggacca acggctcgca gttcttcatc accgtcgctc
    33661 ccaccgcctg gctgaaccgc aagcacacca tcttcggcga ggtcgcggac gcggccgggc
    33721 ggaaggtcgt ggacgccatc gtctccgtcc cgaccaaccc acgcacccac cgtccggtgg
    33781 aggacgtggt gatcgagtcg gtggccgtgg agacccgcga gggctgaccc ggtccgccgg
    33841 ggaaccattt gccccgctcg tccgtaagga cggtggggtg cctcctcttg ccggacggcg
    33901 ccccgtgacc accgacgacc tggggggatc tcatggagca ggctcccggc ggcagccggc
    33961 cggaggcgcg gacgccgcct acctgctacc gccacccgga ccgcgagacg ggcatccgct
    34021 gcacgcgctg cgaccgcccg atctgcccgg agtgcatggt gaacgcctcg gtcggcttcc
    34081 agtgcccgga ctgcgtgcgc ggcacctcgg gcggcggccc gtccccggcg gcggcgcggc
    34141 cgcgcacgat cgcggggggc tcggtgagcg cggatccccg cctggtcacc aaggtcctca
    34201 tcgggatcaa cctcgccgtc ttcatcgccg tgcaggtcag caagacggtg ctgaacgacg
    34261 tggtgctcat cggcgcctgg ccgcctgccc cgttccaccc caccgagggg gtggccggcg
    34321 gggagtggtg gcggatggtg acgagcatgt tcgcccacga ggccgtctgg cacttcgcct
    34381 tcaacatgct cggcctgtgg tggctgggcg gcccgctgga ggcggcgctc ggccgtgccc
    34441 gctatctcgc gctgtacttc acctcgggcc tggcaggcag cgcgctcacc tatctgctgg
    34501 cctcgcccag ctcggccacc ctcggcgcct ccggcgccat cttcggcctc ttcggcgcga
    34561 cggccgtcct catgcgccgc ctgaactacg acatgcggcc gatcatcgcg ctgctggtga
    34621 tcaacctgat cttcaccttc gggtggtcga tcatcgcctg gcaggcccac atcggtggcc
    34681 tggtcgccgg cgtggtcgtg ggctacgcga tggtgcacgc cccgcgtgat cggcgcgcgc
    34741 tggtgcagta cggcacctgt gcgctggtgc tcgccgcggt cgttctggtc accctgttga
    34801 ggacggccca gctcacctga gcggcccgtt gtccacaggc cgtggcgaat cttgtgcaca
    34861 gcgtgcggga acaggtgtgc cccctgccga cgagccgcgt ttccgcaggt caggcagggg
    34921 gcgaacaagc tttcgagtgg ggcgcccgat cggtacttcc gtcacaccgg cgtcaaccgc
    34981 cgagaggtta tccacagatc gtcgttcttt tatccccatg gtgtggacgg gatctgtgga
    35041 taactcagcg catacccctg ggcagggcta cttccactgc gtggagacac cgaatccggc
    35101 ggcgatgaag ccgaagccga ccacgatgtt ccagttgttc aggctgtcga tgggcagaga
    35161 gccgtcggtg acgtagaaga cgacgatcca ggccagaccg atcaggaaca tcgccagcat
    35221 gaccggggcg acccagccgc ggttctccag cttgatcgcg gccgcctgct tggccggcgg
    35281 cggcgtgtag tcggccttct tgcggatacg tgacttcggc acgagggtct ctcctgtcga
    35341 tgcgctgcgt ggccgcgcag ggaacggggt cgggggacac tgagcactcc cccgggcgtc
    35401 cgttagcgta gtgcttccgt ggcgccgaag gagataaggg tacgttgagc aattctgccg
    35461 actcccccca gccgggatcc agtgccgccc accggggcgg cttccgtccc gtccgcgtgc
    35521 tcacggtggc cgtcttcgct ctcgcgggcc tccttttctt caccagtttc caaacggcca
    35581 agggcaccaa tatccgtacg gatacgtcct tgttgaagct ttccgacctc atccaggagc
    35641 gcagccgcaa gaacaaggaa ctggacgact ccaacgccgt gctccgcgac gacgtcgagg
    35701 ccctcgccgg acgcgacaac ggcagcacca aggccgacga cgaccggctc accgccctgg
    35761 agaagagcgc cggcgcccgg aagctcaccg gcgaggcgat cacggtcacc ctgaacgacg
    35821 ccccgccgaa cgccaccgcc aagctgcccg gctaccccga gccgcaaccc gactacctgg
    35881 tcatccacca gcaggacctg caggccgtgg tgaacgcgct gtggcagggc ggcgccaagg
    35941 gcatcaaggt catggaccag cggctgatct ccaccagcgc cgtgcgctgc gtcggcaaca
    36001 ccctgatcct ccagggccgc gtctactcgc cgccgtacaa gatccaggcg gtcggtgacc
    36061 cggaccggct ccagcaggcg ctcgcggact ccccggcgat ccagaactac atggtgtacg
    36121 tgaacgtgta cggcctcggc tggaaggtca ccgaggacgg caccgtgacc ctgcccggct
    36181 acaccggcac cctggacctg cactacgccc agcccgtgcg gtgacacccc acccaccctg
    36241 tggacacagg ccaacggaag gcgccgcgcc gttagtctgg tggcggtacg gcgtgagtgt
    36301 ggtgccgtgg gctacggaag ggacggcatg tacggctgga tctggcggca tctgccggga
    36361 aacgcctgga tcaaggcgct gacctcgatc gtgctggtcc tggccgtggt ctacgtcctg
    36421 ttccagtacg tcttcccgtg ggccgaaccg ctgcttccct tcaacgatgt gacggtggac
    36481 aactcgtgag cgcgcgcatc ctcgtcgtcg acaactacga cagcttcgtc ttcaacctgg
    36541 tccagtacct ctaccagctc ggggccgagt gcgaggtcct gcgcaacgac gaggtgtcga
    36601 cggcccatgc caacgacggc ttcgacggcg tcctgctctc gcccggcccc ggcaagccgg
    36661 aggaggcggg cgtctgcatc gacatggtcc gccactgcgc cgccaccggc gtccccgtct
    36721 tcggcgtctg cctgggcatg cagtcgatgc aggtggcgta cggcggtgtg gtggaccgcg
    36781 cgccggagct gctgcacggc aagacctcgc tggtcgagca cgagggccgg ggcgtcttcg
    36841 ccggactgcc ctcgcccttc accgcgaccc gctaccactc cctggccgcc gagccgccga
    36901 ccgtgcccgc cgagctggag gtcaccgccc gcacccgcga cggcatcatc atgggcctgc
    36961 gccaccgcga actccccgtg gagggcgtgc agttccaccc cgagtcggtg ctcaccgagc
    37021 acgggcaccg gatgctggcc aactggctgg ccgagtgcgg cgacgagggt gccgtggcga
    37081 ggtctgcggg gctcgccccg gtggtgggca gggccacggc gtgaccgcgc tgcgccccga
    37141 gcgcgaggac tcgtacggcc cgacgccgta cgagccctac ggcacgacgt cgtacggggc
    37201 gcaggacggg acgtacggcg acgaggcgta cggggacggg acgtacccgg acgaagagca
    37261 cggcgacggg acgtacgacc cgtatgtgcc ccccgccgac gacgagacga tggcgctgcg
    37321 ggtgccgccg ccccccggca gcggctccat agccgcctct gacgccccat ccgcctcagc
    37381 ggccaccgga gtcacccccg gcggccgtgc ggcccgcaga aaggccgcca agcgccgccg
    37441 cggccgtcac ggcggccccg cccaggccga cccgccggcg gaggagaagc caccggcccc
    37501 cctctcccgg gtcgaggccc gccggcaggc ccgggcgcgc aaacccggcg cgggggtcgt
    37561 cgtcagccgg gccatcggcg agctgttcat cacgaccggc gtgctgatgc tgctgttcgt
    37621 cacctaccag ctgtggtgga cgaacgtgcg ggcccacgcg caggccggca aggaggccag
    37681 cgacctccag caggagtggg cggacggccg gcgcaacccg ggggtgttcg cgcccgggca
    37741 gggcttcgcc atcctgtaca tccccaagct cgacgtggtg gtgcccatcg ccgagggcgt
    37801 cagcaacaag aaggtcctgg acaagggcat ggtcggccac tacggccagg atccgctgaa
    37861 gaccgcgatg cccggcgaca agaccgggaa cttcggcctg gcgggccacc gcaacaccca
    37921 cggcgagccg ttccgctaca tcaaccggct ccagcccggc gacgaggtcg tcgtcgagac
    37981 ccaggacacc tactacgtct acaagacgac gtcgacgctg ccggtgacct cgccgagcaa
    38041 cgtctccgtc ctcgaccccg tccccagggg ctccggcttc accgcccccg gccgctacat
    38101 caccctcacc acctgcacgc cggagttcac cagcaagtac cggctgatcg tctggggcaa
    38161 gatggtcgag gaacggccgc gcagcaaggg caagccggat gcgctcgtca gttaagggca
    38221 gataacagtg gcagcgaccg cagaggacac cgacacgtcc cctcccccct ccccccggcg
    38281 ccgccgcggc accggccgga tcgcgatgac cgtcagcgtc ctcggtgaac tcctcatcac
    38341 ggcgggcctg gtgctcggcc tgttcgtcgt ctactccctg tggtggacga acgtcatcgc
    38401 cgaccgggcg gcaaaccggc aggccgacaa ggtccgcgac cactgggcgc agggcgacgg
    38461 cggcacgggc gggccgggcg ccctggacac caaggacggc atcggcttcc tgcacgtgcc
    38521 cgccatgaaa aacggcgagg tcctggtcga gaagggcacc tccaccaagg tcctcaacga
    38581 cggcgtggcc ggctactaca ccgacccggt caaggccgtc ctgcccacct cgggcaagga
    38641 gggcaacttc tccctcgccg cgcaccgcga cggccacggc gcgaagttcc acaacatcga
    38701 caagctgaag aagggcgacc cgatcgtctt cgagacgaag gacaagtggt acgtctacaa
    38761 ggtctacgcc gtccttcccg agacctcgaa gtacaacgtg gacgtcctcg cccaggtccc
    38821 gaaggagtcc ggcaagaaga agccgggcca ctacatcacc ctgacgacct gcaccccggt
    38881 cttcacgagc cgctaccggt acgtggtctg gggcgaactg gtccgcgtcg accaggtcga
    38941 cagcgagcgc accgagccgg cggaactgcg ctgagccgag cacgacggag ccccggcatc
    39001 cttggactgg atgccggggc tcggtcgtgt gcgcggggcg ccggtcagcc gaagaggccg
    39061 ccgccgttgt cgccgttgtt gttgccgccg cccccgccga agtcgacggt ggtcagcgtg
    39121 accgtctggc tcgccgggtc ggccggcgtg ccgccctgcg ggtcctggtt gatcacgatc
    39181 gccttgtcgt cctggctgcc gagcacgttg atgttgttga agccggcgtc ctggagggcc
    39241 ttccgggcgt ccttcagcgg ctggttgcgg accgtcggga cgggcgtctg ctgctgctgg
    39301 aacttgccga ccttgatctg gacctcggag cccttcttga cctccgtgcc cggggacggg
    39361 tcggtgccga tgaccttgcc gtcctggtcc tgactggtga cctgggtctc gacgcaggtg
    39421 ccgacgagat cgttggcgac catgcgggcc ttggcgtcgt cacaggacag gccgttggag
    39481 acgtccggca cggtcgtggt ggccggggcc accgccaccg tcagggtgat cttcgagccc
    39541 ttctccagct cggtgtcgcc cttggggtcc tggtcgatga cgacaccggg cgtctggtcg
    39601 gactcctcgg acttcttctc gacctcgaag cccttctcct ccagccgggc cttggccttc
    39661 tcgaaggaca gcccctggac gtccggcacg ggcagcttgg gagcgcccgt cgacaccgtg
    39721 agggtgaccg tgtcgccctt cttgacctcc gtcttgaagg cggggtcctg cttgcagacg
    39781 ttgttcaggg gctggttctc gcagggctcc ttcttgatcg tcaccttcag gtcggagttg
    39841 accgcctgct tccgtgcgtc gtccacggtc aggcccacga aattcggcac cggcacggtg
    39901 tcgttgcccg cacccccgcc gctggtgatc cacttgccga tcagcaccgc gccgacgagg
    39961 accaggaccg ccgccacgac cagcaggatc gtggaggcgt tggacttctt ctggcggcgc
    40021 cggtcggggc ggtcgtcgta gccgtagccc ccgtcgtcgg ggttcatcgg cggcagcatc
    40081 gtcgtcgccc cggcggccgc gcccggctcc gcgcgcaggg cggtcgtcgg ctggtcgtcg
    40141 gggtagccgc cgtagccgac cgagcccatc gccgcggccg cgccgaccgg ctgcccgtcg
    40201 aggcacgcct cgatgtcggc gcgcatctcg tcggccgact ggtagcggta gttggggtcc
    40261 ttgacgaggg ccttcagcac gatcgcgtcc atctcgggcg tgatctccgg gtcgaagacc
    40321 gaaggcgcct gaggctcctc gcgcacgtgc tggtaggcga ccgccaccgg cgagtcgccg
    40381 acgaacggcg ggcgcaccgt cagcagctcg tacagcagac agcccgtgga gtacaggtcg
    40441 gaccgcgcgt ccacctgctc gcccttggcc tgctccgggg agaggtactg ggcggtgccg
    40501 atgaccgcgg ccgtctgggt catggtcatg ccggcgtcgc ccatggcgcg ggcgatgccg
    40561 aagtccatca ccttgacctg gccggtgcgc gtcagcatga cgttggccgg cttgatgtcg
    40621 cggtggacga tgccgttgcg gtgcgcgtac tccaggccct ggaggatgcc gatggtcatc
    40681 tccatcgcgc gctcgggcag cagcttgcgg ccgctgtgca gcagctcgcg cagcgtggag
    40741 ccgtcgacgt actccatgac gatgtacggg atcgagaccc cgtcgatgta gtcctcgccc
    40801 gtgtcgtaga ccgcgacgat cgcgggatgg ttgagcgagg cggccgactg ggcctcccgg
    40861 cggaaccggg cctggaagga cgggtcgcgc gcgaggtccg cacgcagggt cttcaccgcc
    40921 acctggcgcc cgaggcgggt gtcatgcgcg aggtagacct ccgccatgcc accacggccg
    40981 agcacctggc ccagctcgta ccggccgccg aggcgacgcg gctcttccat agcttcct
//
