LOCUS       NZ_BNBR01000004        67331 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces griseosporeus strain JCM 4766 sequence04, whole genome
            shotgun sequence.
ACCESSION   NZ_BNBR01000004
VERSION     NZ_BNBR01000004.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces griseosporeus
  ORGANISM  Streptomyces griseosporeus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 888469)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 112X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014656055.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 05:04:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,365
            CDSs (total)                      :: 7,282
            Genes (coding)                    :: 7,186
            CDSs (with protein)               :: 7,186
            Genes (RNA)                       :: 83
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 96
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 96
            Pseudo Genes (frameshifted)       :: 41 of 96
            Pseudo Genes (incomplete)         :: 61 of 96
            Pseudo Genes (internal stop)      :: 11 of 96
            Pseudo Genes (multiple problems)  :: 15 of 96
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:46:46
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 821138
            Orig. end                         :: 888469
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BNBR01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..67331
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="T2PKS"
                     /product="butyrolactone"
                     /region_number="3"
                     /rules="(t2ks and t2clf)"
                     /rules="AfsA"
                     /tool="antismash"
     cand_cluster    1..67331
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(t2ks and t2clf)"
                     /detection_rules="AfsA"
                     /kind="neighbouring"
                     /product="T2PKS"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..67331
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[35000:37483](+)"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="8|9 (Score: 701.6; E-value:
                     5.9e-214)"
                     /t2pks_molecular_weights="acetyl-CoA_8 (Da): 386.437"
                     /t2pks_molecular_weights="acetyl-CoA_9 (Da): 428.474"
                     /t2pks_product_classes="angucycline"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
                     /tool="antismash"
     proto_core      35001..37483
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="8|9 (Score: 701.6; E-value:
                     5.9e-214)"
                     /t2pks_molecular_weights="acetyl-CoA_8 (Da): 386.437"
                     /t2pks_molecular_weights="acetyl-CoA_9 (Da): 428.474"
                     /t2pks_product_classes="angucycline"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
     misc_feature    complement(911..924)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.28"
                     /tool="antismash"
     gene            937..1224
                     /locus_tag="IE308_RS22700"
                     /old_locus_tag="GCM10018783_46230"
     CDS             937..1224
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049141.1"
                     /locus_tag="IE308_RS22700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46230"
                     /product="chaplin"
                     /protein_id="WP_110627898.1"
                     /transl_table=11
                     /translation="MRVITRVLAATAIAGLTVLGTSAAAQAAPAGTDGALSHPCDDSGA
                     CAVGTAIGSPGVLSGNVIQIPIDLDVNACGNSINVVGLLNPAFGNTCVND"
     gene            complement(1244..1894)
                     /locus_tag="IE308_RS22705"
                     /old_locus_tag="GCM10018783_46240"
     CDS             complement(1244..1894)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014672406.1"
                     /locus_tag="IE308_RS22705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46240"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_190219326.1"
                     /transl_table=11
                     /translation="MPAAPKPEILAAFEAAKGFMPVDEGLALYDAAVAAGRLGLPLLEV
                     GTYCGRSTILLADAARAAGVVAVTVDHHRGSEEQQPGWEYHDPETVDPEVGLMDTLPTF
                     RRTLHKAGLEQHVVAVVGRSPQVAKVWAAPVGLVFVDGGHTDEHATADYEGWAPHVAEG
                     GVLVIHDVFPDPVDEFTGQAPYRVYLRALESGAFTEVSATGSLRVLRRTGAGI"
     gene            complement(2064..3800)
                     /locus_tag="IE308_RS22710"
                     /old_locus_tag="GCM10018783_46250"
     CDS             complement(2064..3800)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009188337.1"
                     /locus_tag="IE308_RS22710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46250"
                     /product="MFS transporter"
                     /protein_id="WP_190219327.1"
                     /transl_table=11
                     /translation="MTLTSTDRPAPREGGAAVVPVLAFAGIVVAVMQTLLVPVIKDLPQ
                     LLGTSPSNATWVLTSTLLSGAVATPIMGRLGDLYGKRRMLILSLAVMVAGALVSAVTSN
                     LLLMIGGRTLQGFAMGAIPLGIGLMRDMLPREKLGSAMALMSSSIGVGGGLALPAAALV
                     AQHTDWHALFYGAAGLGVLSIVLTLLVVPESPMRAEGSFDLPGALGLSAGLVLLLLPIT
                     KGSDWGWSSGTTLALFAAAVVVLLGWGVVELRTKAPLVDLRTTARREVLLTNLASIMVG
                     VSFYVVSLVLPQLLQLPTATGYGLGQSMVVAGLCVAPLGLTMMFTAPVYARLSARYGPK
                     ATLIIGLLVIAVGYGGGLGLMDAAWQTVLTSVVLGVGIGLAYSSLPALIVGAVPASETG
                     AANGLNTLMRSIGTSVSSAVIGMVLANTADHVGGVAVPTMHGFRVSFLIATAAVAVGLL
                     MALFLPKPDRAPRLRASSEEEANLERAEEVLRGFRGRVLDAGGAPVARAKVTLIDRRGR
                     RAGSALSDEEGRYVLAVPSGGPYVVAAKASGHGPHASSATHAGDERAVELDLSLPGEAV
                     RA"
     misc_feature    3844..3858
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.0"
                     /tool="antismash"
     gene            3990..5468
                     /locus_tag="IE308_RS22715"
                     /old_locus_tag="GCM10018783_46260"
     CDS             3990..5468
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015576975.1"
                     /locus_tag="IE308_RS22715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46260"
                     /product="MFS transporter"
                     /protein_id="WP_110627895.1"
                     /transl_table=11
                     /translation="MTRMLDAADAAARAPRRPAPPAWLVVTLACAGQFLVVLDVSVVNT
                     ALPSMRADLGLSDSGLQWVVNAYAIAFAGFMLLGGRAGDLYGRKRMFLVGLALFTLASL
                     GGGLAQDGWQLLLARAVQGLGAAVLAPSTLTLLTAAVPEGPARARAIATWTAVGGGGGA
                     AGGLVGGVLVDALSWRWVLLINVPIGAVVLLGALRWLPESRAGDRRRLDLPGAVLVTAG
                     LATVAYGISQTESEGWTAQATLLPLAAGAALIALFLAVEARTAAPLMPLRLLRLRSVAS
                     ANTAMFLSGAAMFCMWFFMTLYAQNVLGYSPLEAGVALVPSSLAVVLGSKLAPRFMPVA
                     GPRVVAVLGTLVAAAGFGWQSTMSAHGDYVTGILVPGVLMMLGAGLAATPLASLATSGA
                     APEEAGLVSGLVNTSRTMGGSLGLAVMSTIAAARTAGSTTPQALTDGYALAFRASTAVL
                     LTGAVLMLLWLPRPPRTAPAGAAVPQKAGNSSAR"
     gene            5520..6059
                     /locus_tag="IE308_RS22720"
                     /old_locus_tag="GCM10018783_46270"
     CDS             5520..6059
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020116029.1"
                     /locus_tag="IE308_RS22720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46270"
                     /product="SigE family RNA polymerase sigma factor"
                     /protein_id="WP_110627894.1"
                     /transl_table=11
                     /translation="MGDRKQAGDEEFRAFVAGRWPRLMRTAFLLTGEQHAAEDLVQSTL
                     EKAYVAWRRVGSADDPEAYVRRVMINTHARRHRRKLREFLAPRDDSGIAREVPDSGDHI
                     SRAEDRGLLLQALAQLPPRQRQAVVLRYWEDLTETQAAEAMGCSVGAVKSNTAKGIAKL
                     RAIPELADTVMYGGRK"
     misc_feature    5543..5557
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.53"
                     /tool="antismash"
     gene            6056..6883
                     /locus_tag="IE308_RS22725"
                     /old_locus_tag="GCM10018783_46280"
     CDS             6056..6883
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014672403.1"
                     /locus_tag="IE308_RS22725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46280"
                     /product="hypothetical protein"
                     /protein_id="WP_229909000.1"
                     /transl_table=11
                     /translation="MTNANREFDHGMTDRDIAFLLADAASAVEIGTAPTQAVIRGGRRR
                     RARRWAVTAATAALVAGSTGALAVTALPGDGGHRVAPATPPATSATPGPVLQPDPTTLA
                     TGTDQGTPWKVTLDVWPAPRDETEAQTLLGAMTTYGEFPADVHKASDLVGRSAYTVRQS
                     HGDGDTLGTPVSEGLTAPADRMAGTDLDSVAVPLDPDTPGRPQRLVVGHVARTAQEVTC
                     TWKNGTTTKVHRATSTDINSDDQTIRTPATSPYAWFVCLAPDGTAFESVAVTR"
     gene            complement(6956..7588)
                     /locus_tag="IE308_RS22730"
                     /old_locus_tag="GCM10018783_46290"
     CDS             complement(6956..7588)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013004115.1"
                     /locus_tag="IE308_RS22730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46290"
                     /product="response regulator transcription factor"
                     /protein_id="WP_190219406.1"
                     /transl_table=11
                     /translation="MPRDHRPGKSIRVLLAEDQGMMRGALALLLGLEPDIEVVAQVGAG
                     DAIVDAALTHRPDVALLDIELPGRSGLDAAADLRDQAPDCRVLILTTFGRPGYLRRAME
                     AGAAGFLVKDGPVEELAVAIRRVLTGETVIDPALAAAALSAGPNPLTARECDALRASAD
                     GATVADIAARLHLSESTVRNYLSSAIGKTGTRNRMEAMREARRQGWL"
     gene            complement(7660..8112)
                     /locus_tag="IE308_RS22735"
                     /old_locus_tag="GCM10018783_46300"
     CDS             complement(7660..8112)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019547366.1"
                     /locus_tag="IE308_RS22735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46300"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_190219328.1"
                     /transl_table=11
                     /translation="MTQEPTARALSDEALSDLLSRQQFGTLATTKRSGHPHLTTMVYSW
                     DPEARLVRFSTTADRIKVAHLRRDPRAALHVQGPDVWSFAVAEGTAEVSDVTAAPGDAV
                     GRELLSMLPESARPQDEEAWLARQVEERRVVVRLKAERLYGTAIDF"
     gene            complement(8109..9377)
                     /locus_tag="IE308_RS22740"
                     /old_locus_tag="GCM10018783_46310"
     CDS             complement(8109..9377)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019982135.1"
                     /locus_tag="IE308_RS22740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46310"
                     /product="sensor histidine kinase"
                     /protein_id="WP_190219329.1"
                     /transl_table=11
                     /translation="MRGLRSRKTCRAHGERERHAGPPPTGFTLLPWLLMGMGSLSNLFQ
                     GETPNPLIGGLGLLTFNSLYVFLAFRAFDRRKRDAPATRVALLLLALLTCALAIGYGGN
                     WLLFFPLLGLAVGAVLRGPGLGRWGWSLAVLAGAVAGVKEGWDGIGILYGTFLSTMVTS
                     AILSLSEAVRELRAAREELARRAVEEERLRFSRDLHDLLGHTLSVIVVKSEAARRLAPR
                     DLDASLAQINDIESVGRQALTEIREAVTGYRENSLATEVDRARSVLTAAGVEPTVRRSG
                     APLSARTEALLGWVVREAVTNAVRHSGARHCEIAVHGAADRVRLTVTDDGHGPAGAPPS
                     AVGGTGLKGLRERLTAAGGTLTAGPGPHGGFTVTAELPQDTAGAEAGPRSEAELSSGGP
                     TPPPPLPPQAPGMPTPAPELTLP"
     gene            9518..10381
                     /locus_tag="IE308_RS22745"
                     /old_locus_tag="GCM10018783_46320"
     CDS             9518..10381
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016826498.1"
                     /locus_tag="IE308_RS22745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46320"
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="WP_190219330.1"
                     /transl_table=11
                     /translation="MPIDAAQALAAGPRTSRISWTAKDVQLYHLGIRAGADPDDLRYTL
                     EDRLHVLPAFATVAGGGAPGVIRALSMPGVDVDLARALHAGQSLTVHRPLPVRATATAT
                     SRVTGVYDKGTAAVLVLRTEVADADGPLWTEEARTYVRGEGGWGGERGPSVRADVPAGP
                     PEQTVRRAVRADQALLYRLSGDLNPLHADPEFAARAGFERPVLHGLCTYGMTLKAVVDT
                     LLGGDVARVRSYEARFTGVVYPGETLRIRLWREGGTGVVPAVRVAVGVVERGDALVLDG
                     TVLPHG"
     gene            complement(10519..10677)
                     /locus_tag="IE308_RS22750"
                     /old_locus_tag="GCM10018783_46330"
     CDS             complement(10519..10677)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019982131.1"
                     /locus_tag="IE308_RS22750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46330"
                     /product="hypothetical protein"
                     /protein_id="WP_190219331.1"
                     /transl_table=11
                     /translation="MSNATTTQPQDMEVQGSAGHGRHRGPVSTQETETAPRGRHRKPAE
                     QAETTAA"
     gene            complement(10774..12000)
                     /locus_tag="IE308_RS22755"
                     /old_locus_tag="GCM10018783_46340"
     CDS             complement(10774..12000)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326217.1"
                     /locus_tag="IE308_RS22755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46340"
                     /product="hypothetical protein"
                     /protein_id="WP_190219332.1"
                     /transl_table=11
                     /translation="MTACAIEPAAAQEESFPPPPGLVITVDGAYAARLAGEGDALFPER
                     WTLDGPEPYAVPLPGNQPEEPGTEVQPMGDGRVLIHRLAAGRHAFSLLYPTGPGTGELP
                     LGAVERPDDGTLLRLLPPAPGGERAYALAVGRRSSTVWLVAGGAFGPERVAELPGRCSG
                     GVWLDHTGRMLALDRETGGRTKTVVVDLERGGEVSPLLQIAEDSDDRLLLADPDSGLLI
                     VASDAPSPGAPRLGWGVLGSTLPVRFAECLRMPGCTVTPFAIQPGQVLTPEGCGVALRV
                     DGPFGRWVGVWRPAERQVHAFVAPPGWLPGAGRWTAEGVLLLPYATGEEPCGLARVEAP
                     AVVPVPVPEAVPVPGESPALPVDPAVPADPRAQVDPLSPEAESEGPSEPVTPRPVPLCE
                     APLGRLVTK"
     gene            12210..13049
                     /locus_tag="IE308_RS22760"
                     /old_locus_tag="GCM10018783_46350"
     CDS             12210..13049
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0051540 - metal cluster binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015660812.1"
                     /locus_tag="IE308_RS22760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46350"
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="WP_190219333.1"
                     /transl_table=11
                     /translation="MPRLSEVIAALENLWPAERAESWDAVGTVAGDPDQEVTRVLFAVD
                     PVQEIVDEAVKLGADLLVTHHPLYLRGTTTVAASTFKGRVVHTLIKHDIALHVAHTNAD
                     TADPGVSDALAGALDLRVVRPLVPDPGDPEGRRGLGRICELDHPLPLREFAARAAARLP
                     ATAQGIRVAGDPEATIRTVAVSGGSGDSLFDQVREAGVDAFLTADLRHHPASEARAHSP
                     LALLDAAHWATEWPWCELAASQLDEISDRHGWDLRVHVSKTVTDPWTSHSPSPGAPN"
     gene            13046..13789
                     /locus_tag="IE308_RS22765"
                     /old_locus_tag="GCM10018783_46370"
     CDS             13046..13789
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003989855.1"
                     /locus_tag="IE308_RS22765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46370"
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="WP_190219407.1"
                     /transl_table=11
                     /translation="MNAAPADQIRLLDVQALDVRLQQLAHKRKSLPEHAEIESLTKDLT
                     QLRDLLVAAQTEESDTAREQTKAEQDVDQVRQRAARDQQRLDSGAVTSPKDLSNLQHEI
                     ASLAKRQADLEDVVLEVMERRESAQARVAELTERVASVQAKIDDATGRRDAAFEEIDGE
                     AASVTKEREVVAASVPADLLKLYDKLREQQGGIGAAKLYARTCQGCRQELAITELNEIR
                     KAAPDTVVRCENCRRILVRTAESGL"
     gene            13802..15229
                     /locus_tag="IE308_RS22770"
                     /old_locus_tag="GCM10018783_46380"
     CDS             13802..15229
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019522456.1"
                     /locus_tag="IE308_RS22770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46380"
                     /product="bifunctional RNase H/acid phosphatase"
                     /protein_id="WP_190219334.1"
                     /transl_table=11
                     /translation="MREFIVEADGGSRGNPGPAGYGSVVKDAATGQTLAERAEYIGVAT
                     NNVAEYRGLLAGLRAAHELDPAAPVHVRMDSKLVIEQMSGRWKIKHPDMKPLAAEAARV
                     YPPGQVTYEWIPREQNKHADRLANEAMDAGKRGEQWDPSASRAELDAVRAAAPAAPAAP
                     AVPEPSGPPGDATAGAARARAALAEGRAPKAQEEKAQERQQADAGDKAEADVRAARTTA
                     ATTGTTATTGTTAPTGTAASTGTTAPTGTTATPSVSAPGWSSAPDLGAPATFVLLRHGE
                     TPLTPQKRFSGSGGTDPSLSDIGREQAERVAAALARRGTIQHIVTSPLARTRETAGIVA
                     ARLGLEVTVEDGLRETDFGAWEGLTFGEVRERHPDDLNAWLASPEAAPTGGGESFAETA
                     TRIAAARDKLVAAYAGRTVLLVTHVTPIKTLVRLALGAPPESLFRMELSAASLSVVAYY
                     ADGNASLRLLNDTAHLR"
     gene            complement(15280..15921)
                     /gene="eda"
                     /locus_tag="IE308_RS22775"
                     /old_locus_tag="GCM10018783_46390"
     CDS             complement(15280..15921)
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /GO_function="GO:0008675 -
                     2-dehydro-3-deoxy-phosphogluconate aldolase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008700 - 4-hydroxy-2-oxoglutarate
                     aldolase activity [Evidence IEA]"
                     /GO_process="GO:0009255 - Entner-Doudoroff pathway through
                     6-phosphogluconate [Evidence IEA]"
                     /codon_start=1
                     /gene="eda"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004931825.1"
                     /locus_tag="IE308_RS22775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46390"
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="WP_190219335.1"
                     /transl_table=11
                     /translation="MPAALPASVLDLAPVLPVVVVDDAADAVPLARALVAGGLPAIEVT
                     LRTPAALESIRAIAGAVPDAVVGAGTVLTPGQVAESVAAGARFLVSPGWTDVLLEAMRG
                     AGVPFLPGVSTATEVVALLERGVREMKFFPAQAAGGTAYLRSLAGPLPQARFCPTGGIG
                     PDTAPDYLALPNVGCVGGSWMLPADAVAARDWGRVERLAREAATLTAGVR"
     gene            complement(15995..16777)
                     /gene="yaaA"
                     /locus_tag="IE308_RS22780"
                     /old_locus_tag="GCM10018783_46400"
     CDS             complement(15995..16777)
                     /codon_start=1
                     /gene="yaaA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020140030.1"
                     /locus_tag="IE308_RS22780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46400"
                     /product="peroxide stress protein YaaA"
                     /protein_id="WP_190219336.1"
                     /transl_table=11
                     /translation="MLVLLPPSEGKAPSGTGAPLTLESLSLPGLTAARAAVLEELVELC
                     AGDEEKAREVLGLSEGLRGEVGKNAGLREAGARPAGEIYTGVLYDALGLAALDEEARRR
                     AGAWLLVFSGLWGAVRVTDRIPSYRCSMGVKLPGLGALAAHWRAPMAEVLPEAAGEGLV
                     LDLRSSAYAAAWKPKGEVAGRTATVRVLHAPTRKVVSHFNKATKGRIVRSLLTAGAAPQ
                     GPAELVTALRDLGYAVEAEAPGKAGKPWALDVLVEEIH"
     gene            16855..18285
                     /locus_tag="IE308_RS22785"
                     /old_locus_tag="GCM10018783_46410"
     CDS             16855..18285
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0004540 - RNA nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014672390.1"
                     /locus_tag="IE308_RS22785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46410"
                     /product="RNB domain-containing ribonuclease"
                     /protein_id="WP_110627883.1"
                     /transl_table=11
                     /translation="MPRRPLHVTGAPEGPLLTALAALRDKLHVPAGFPPDVLAAADEAA
                     AHPVLPAEDATDIPFFTIDPPGSLDLDQAMHLSRQGTGYRVRYAIADVAAFVVPDGPLD
                     REAHHRAVTLYFPDLRIPLHPPVLSEGAASLLPGQTRPAAVWTIDLDASGGTLAVDVRR
                     ALIRSKQRLDYDSVQKKIDDGTAEEPLLLLKTIGLLREQVEIARGGISLRVPDQEIVEH
                     DHTYELTYRAPLAADGWNAQLSLLTGMAAAELMLAHGTGVLRTQVPKPGKLEELHHTAD
                     ALHIDWPPHMSYAERVRTLDPSVPREAAFLQACTGLMRRADYTVFRDGHLPPNPVHASV
                     AAPYAHCTAPLRRLVDRYATEICLAAVAGREPPEWVLAALDAVPARMKEGGERAGDIDG
                     KCVDLVEAAVLKDRVGEIFEGVVVKQGNPPGTGTVQLESPAVVGPVTGITETDVGRRLQ
                     VRLTRADMEVPTVSFALA"
     gene            18404..18982
                     /locus_tag="IE308_RS22790"
                     /old_locus_tag="GCM10018783_46420"
     CDS             18404..18982
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007381639.1"
                     /locus_tag="IE308_RS22790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46420"
                     /product="Uma2 family endonuclease"
                     /protein_id="WP_190219337.1"
                     /transl_table=11
                     /translation="MTAMAHEPLTQEEVLLEGFLALDTPEGFRAELIEGEIVVTPPPDG
                     EHEKYISRIVRQVIKLSRTDMDFSGNKGLRLRSGGGCPKSHVIPDVTFAPFDLDLFGGA
                     ESWMPCDGVAMVLEVTSARPQADREAKRRCYARGGIPLYLLADRDTSQVTLFSDPDKDD
                     YRALTTRPFGKPITLPEPFAFDLDTADLL"
     gene            19078..19917
                     /locus_tag="IE308_RS22795"
                     /old_locus_tag="GCM10018783_46430"
     CDS             19078..19917
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1015: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016435596.1"
                     /locus_tag="IE308_RS22795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46430"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_190219338.1"
                     /transl_table=11
                     /translation="MADQGREEALWTRARLGRCGPALDLLTARFDQHVYAPHAHDEYTV
                     GVCVGGSEVIAYRGGRVHAGPGSIVVLAPGEIHTGGPATTTDGYAYRALYAAPDLLADG
                     VLGGGGLPHFREALIDDPELATALRRAHSETAACPDPLEAESRLPWLLTALARRHSTAR
                     ATSDAVAGADGIARQVRDRLADELTDPPSLSALATELGLSRYQLLRAFRTSVGVPPYAW
                     LAQHRVTRARALLESGLRPAEVAGLVGFADQAHLTRWFRRVLGVTPAAYRNSVQDAR"
     cand_cluster    19260..30168
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    19260..30168
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[24259:25168](+)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      24260..25168
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="2"
     gene            20003..>20719
                     /locus_tag="IE308_RS37490"
                     /old_locus_tag="GCM10018783_46440"
                     /pseudo=""
     CDS             20003..>20719
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013088.5"
                     /locus_tag="IE308_RS37490"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46440"
                     /product="DMT family transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIKVAVDELSPSMVVFVRCAVGAALLLPFALRQPGLARTVVSHWR
                     PMLAFACIEIIGPWFTLTDAERHLSSSTAGLLIAGVPIVGVALARYFGATERLGIRRLT
                     GLALGLTGVVVLTLPHLTGGDARSLAEVLLTVIGYATAPLIAARHLKDVPSLHLTAPCL
                     ALAALVYAPAAAATWPSQTPSASVLASLAGLGVICTAVAFVAFLELIKEAGPTRATVIT
                     YVNPAVAVAAGALFLNE"
     ncRNA           20835..21249
                     /db_xref="RFAM:RF00010"
                     /gene="rnpB"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="IE308_RS22810"
                     /ncRNA_class="RNase_P_RNA"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /product="RNase P RNA component class A"
     gene            20835..21249
                     /gene="rnpB"
                     /locus_tag="IE308_RS22810"
     misc_feature    complement(20943..20955)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 18.92"
                     /tool="antismash"
     misc_feature    21335..21348
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.92"
                     /tool="antismash"
     misc_feature    21438..21451
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.21"
                     /tool="antismash"
     misc_feature    complement(21544..21562)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.48"
                     /tool="antismash"
     gene            21544..22101
                     /locus_tag="IE308_RS22815"
                     /old_locus_tag="GCM10018783_46450"
     CDS             21544..22101
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020140397.1"
                     /locus_tag="IE308_RS22815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46450"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_190219340.1"
                     /transl_table=11
                     /translation="MQKRSQSTRQELVYAAVQLIANGRFADAGLVNICNTAGVSRGALY
                     HHFTSIAELLAEVYAQAEKRVLALADDSFASRGAGAPARFGIALGKALAEDQLVRAGVR
                     LAADGTDSPPRLREELLARLREEVLGDAPVTPEREVLADLAVVVTAGLISLGYTDTTWW
                     RPESTQRIWDALLPLFTDAERR"
     gene            complement(22170..22814)
                     /locus_tag="IE308_RS22820"
                     /old_locus_tag="GCM10018783_46460"
     CDS             complement(22170..22814)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020140398.1"
                     /locus_tag="IE308_RS22820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46460"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_190219341.1"
                     /transl_table=11
                     /translation="MAKQERGTRSRRAILRAAAEVFDERGYDAASTNEILARSGLTRGA
                     LYHHFPSKEAIAAALLEAHSEALVAPDDSTKMQAIIDLTFGFAYRLQRDPVLRASVRLA
                     VEDTSFTRPVNTPYEQSSATIRGLLEQAREQGETLPGLDLTEATTMIVGSFTGMQVMSQ
                     VYTNRKDLPERVTTMWRLLLPGIVSPGMIGHLRVTPPPAPAAAPEPAAVGA"
     misc_feature    complement(22807..22821)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     gene            complement(23028..23798)
                     /locus_tag="IE308_RS22825"
                     /old_locus_tag="GCM10018783_46470"
     CDS             complement(23028..23798)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020140399.1"
                     /locus_tag="IE308_RS22825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46470"
                     /product="response regulator transcription factor"
                     /protein_id="WP_110627879.1"
                     /transl_table=11
                     /translation="MNRQVADAPGARTRWEHSAHHPGHPTPPRLHAPVEHAALRVLVVE
                     EEERAAKTLVQNLTRRGYRAESVATGTQALQVHHQVDLILLDLDLTDLDGLEVCRGIRA
                     VSDTPIIAVTERGSELDRVLGLQAGADDYMVKPYGFHELLARIGAVMRRVRPSRTSRVI
                     EHGPLRIDPVARKVTLHDRPVDLTRKEFDLLRILALQPGAVVSRRQLMSQVWDDAWSHK
                     GRTIDTHVSSLRGKLGSSDWIVTVRGVGFRLGNP"
     misc_feature    complement(24047..24062)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.14"
                     /tool="antismash"
     gene            24260..25168
                     /locus_tag="IE308_RS22830"
                     /old_locus_tag="GCM10018783_46480"
     CDS             24260..25168
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008740559.1"
                     /locus_tag="IE308_RS22830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46480"
                     /product="ScbA/BarX family gamma-butyrolactone biosynthesis
                     protein"
                     /protein_id="WP_190219342.1"
                     /sec_met_domain="AfsA (E-value: 2.6e-22, bitscore: 74.3,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAMLDTALTTIVPRQYVHRAAVSEVLLTGWQAAEQADAFVVRAQ
                     WPRGHALFAQSGGYQDPLLLVESVRQIGSLLSHAEYEVPFGHQFLMLGIGFSATRDMFV
                     ATPAPTEVELHTVCRDIVRRGKALAGMRYEVTAMVDGVALATASAAFKCTAPGVYQRLR
                     GDRPTRANRLPGLPVDPALVGRTGTEHVVLSQDGASGNRWEVRADTDHPIFFDHPVDHI
                     PGMVLLEAARQAAHAATGLTDALVLDLDSSFARYAELDEPCYIEADPLGADDGGDVQVR
                     VHGVQGRQTVFTARLVLRPRA"
     gene            25168..26118
                     /locus_tag="IE308_RS22835"
                     /old_locus_tag="GCM10018783_46490"
     CDS             25168..26118
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (45-197). E-value:
                     2.2e-09. Score: 28.8. Matches aSDomain:
                     nrpspksdomains_IE308_RS22835_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004001135.1"
                     /locus_tag="IE308_RS22835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46490"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_190219343.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 3e-12, bitscore:
                     41.8, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRHPGLGAPHVLVTGAAGFIGARVARAAARHAGRLTLTSYRRPP
                     EPVSGAVRTVRADLADPASLRGLCDGVDVLLHCASQIGGMPEANEAVNARGTAALVAEA
                     RRAGVDRIVYVSTASVYGRGTFRRAHPGQLARRPQSPTSRTRAAAEDAVLAAGGIVVRP
                     HVLYGPGDEWVIPGLGRLLRDLGGTPTGWTSRHSVIAVTELAALLVGVGLAPRERLSAS
                     VYHAAYPAPAPASALLEAAAGCLAAPPPRRELDVAEARELLAGDAAALHTLDLLATDHW
                     FDSEPLWADLGRLPGPGWDADFPRMKEWYPAPAAA"
     CDS_motif       25204..25287
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS22835_0001"
                     /evalue="8.00E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE308_RS22835"
                     /protein_end="40"
                     /protein_start="12"
                     /score="12.1"
                     /tool="antismash"
                     /translation="LVTGAAGFIGARVARAAARHAGRLTLTS"
     aSDomain        25303..25758
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS22835_NAD_binding_4.1"
                     /evalue="2.20E-09"
                     /label="IE308_RS22835_NAD_binding_4.1"
                     /locus_tag="IE308_RS22835"
                     /protein_end="197"
                     /protein_start="45"
                     /score="28.8"
                     /tool="antismash"
                     /translation="EPVSGAVRTVRADLADPASLRGLCDGVDVLLHCASQIGGMPEANE
                     AVNARGTAALVAEARRAGVDRIVYVSTASVYGRGTFRRAHPGQLARRPQSPTSRTRAAA
                     EDAVLAAGGIVVRPHVLYGPGDEWVIPGLGRLLRDLGGTPTGWTSRHS"
     gene            26202..27194
                     /locus_tag="IE308_RS22840"
                     /old_locus_tag="GCM10018783_46500"
     CDS             26202..27194
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014150657.1"
                     /locus_tag="IE308_RS22840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46500"
                     /product="aldo/keto reductase"
                     /protein_id="WP_110627876.1"
                     /transl_table=11
                     /translation="MEYTKLGRSGLTVSRLVLGTMNFGTQTPEEDSHAIMSRAHEHGIN
                     FFDTANVYGTRPGEVSTEEIMGRWFASGGGRRERTVLATKVYIPTGSWPNEGFLSALNI
                     RRACEASLRRLQTDYIDVYQMHHVDRDTPWEEIWEAFSVLRQQGKVLYFGSSNFAGWHL
                     AQAQEAARARHFLGLVSEQSMYNLMTRWVELEVLPAARHYGVGVIPWGPLHGGVLGGVL
                     RKQKEGRTARGSTGRSVGVLARHRDTIEAYEKLCADIGADPAHVGLAWLLAQEGVTGPI
                     IGPRTTEQLDSSLTALTIRLDDATLAKLDELFPPPGPNGARPAPEAYAW"
     gene            27358..29130
                     /locus_tag="IE308_RS22845"
                     /old_locus_tag="GCM10018783_46510"
     CDS             27358..29130
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003948354.1"
                     /locus_tag="IE308_RS22845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46510"
                     /product="biotin carboxylase N-terminal domain-containing
                     protein"
                     /protein_id="WP_190219344.1"
                     /sec_met_domain="ATP-grasp (E-value: 1.4e-08, bitscore:
                     30.0, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKVLIANRGEIAVRVARACRDAGIASVGVYADPDREAVHVRAVD
                     EAFGLGGDTPASSYLVIDKILNAARESGADAVHPGYGFLSENAEFAQAVIDAGLIWIGP
                     PPQAIRDLGDKVAARHIAQRAGAPLVAGTPDPVSGADEVVAFAKEHGLPIAIKAAFGGG
                     GRGLKVARTLEEVPELYDSAVREAVAAFGRGECFVERYLDKPRHVETQCLADKHGNVVV
                     VSTRDCSLQRRHQKLVEEAPAPFLNEEQVAELYRASKAILKEAGYVGAGTVEFLVGLDG
                     TISFLEVNTRLQVEHPVTEEVAGIDLVREMFRIADGEELGYDDPVLRGHSFEFRINGED
                     PGRNFLPAPGTVTRFDAPSGPGVRLDAGVESGSVIGPAWDSLLAKLIVTGRTRKEALQR
                     AARALEEFQVEGMATAIPFHRAVVKDPAFAPELTGSADPFTVHTRWIETEFVNDIKPFA
                     APADAEAEEEAGRETVVVEVGGKRLEVSLPSSLGMSLARTGLAAGAKPKRRAAKKSGPV
                     ASGDTLTSPMQGTIVKIAVEEGQEVKEGDLIVVLEAMKMEQPLNAHKSGTIKGLSAEVG
                     ASLTSGAAICEIKD"
     misc_feature    27388..27399
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.68"
                     /tool="antismash"
     gene            complement(29215..30231)
                     /locus_tag="IE308_RS22850"
                     /old_locus_tag="GCM10018783_46520"
     CDS             complement(29215..30231)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE308_RS22850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10018783_46520"
                     /product="hypothetical protein"
                     /protein_id="WP_190219409.1"
                     /transl_table=11
                     /translation="MNQGSIRMPAVTTACAGHGCARRADGGGDRRPAEPGARLCRPCHD
                     HLVRDLTRLPELYEECARHLDGSGGERCAERTSGGPLPGTPFNSWAAEVRSSILAVLGS
                     WATLVVEELGLAGPRRAVGPLAAFLLRHSGWLARHDAAGDLSAEVARLVRRAHSVMDPV
                     TRRRIPIGECVEPGCPGGLTAVVRPQHPKWPATITCTADGSHRWFGPELLQLSRRLGGA
                     AASAKGATAGTTDTTGTTGTTDRTGTTGMTRTTDTTGATPPTGADAEDRPGSGAAAPQP
                     ETRWVTAADIARLWSMPPGSVYRHASTRKWRRRSQSGRTYYHAADVYETLKHRAGAA"
     misc_feature    complement(30264..30278)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.23"
                     /tool="antismash"
     misc_feature    30394..30409
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    30399..30413
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.77"
                     /tool="antismash"
     gene            30548..31822
                     /locus_tag="IE308_RS22855"
                     /old_locus_tag="GCM10018783_46530"
     CDS             30548..31822
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018890073.1"
                     /locus_tag="IE308_RS22855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46530"
                     /product="MFS transporter"
                     /protein_id="WP_190219345.1"
                     /transl_table=11
                     /translation="MNSPRARTFQSLTIRNFRLFAAGQLVSVAGTWMMVVAQDWLVLAL
                     TGDSGTALGMVTAFQFAPLLLFTLHAGGLADRYDKRRLLICANLTSGALALCLGVLVLA
                     GVARLWHVCLFALGLGLVNAVEVPTRMSFVSELVGADLLPNASALSAAYFNAARVAGPA
                     VAGLLIGWLGTGAVMLLNAVSYLATVAALRAMRPGELHRDGRRPERAPVRDGLRHTAAR
                     ADLLLPMVLVAVVGMLGFNFQLTLPLLAKTVFHARAFDFGLLTTAFAAGSLLAAFVTTH
                     RRGRPPAGLVTGSALAFGALETAAGLAPTYATALVLLLGTGFGAIYFAQAANHRIQLGT
                     DPAYRGRVMALYTLVFQGTTPLGALLIGALSERFGARSGLLAGGVATLLAASAVLVAQR
                     RARPAAAVTGRADEPSTRTSGEPAR"
     gene            32125..32784
                     /locus_tag="IE308_RS22860"
                     /old_locus_tag="GCM10018783_46540"
     CDS             32125..32784
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268983.1"
                     /locus_tag="IE308_RS22860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46540"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_110627872.1"
                     /transl_table=11
                     /translation="MAIQEATITRTPAGSAEERQDVVRAARAVFAREGWTHSGVADIAR
                     ESGLDEATVTHYFPDKERLLLTVLLEGAASVAAALTVIAENHLADVTDLEKDLIALGHA
                     WLTPLADFPEHFAIVRHLGAEIAAWPAGVVEMWRTAGPRQATRELGRRLERLADRGLLA
                     FDDSDHAAERFIQLVAGGVVQRSFHGALPLADFETEALVAAGVADFVRLYRPGAGR"
     gene            32883..34448
                     /locus_tag="IE308_RS22865"
                     /old_locus_tag="GCM10018783_46550"
     CDS             32883..34448
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020141373.1"
                     /locus_tag="IE308_RS22865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46550"
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_190219346.1"
                     /transl_table=11
                     /translation="MATPHDSIQARIDELTEIKEAARLGPDPAATERQHNKGKLTAHER
                     IALLLDKGSFNEVEPLRRHRATGFGLEDKKPYSDGVVTGWGTVHGRTVFVYAHDFRIFG
                     GALGEAHAQKIHKIMDLAEAAGAPLVSLNDGAGARIQEGVTALAGYGGIFQRNTRSSGV
                     IPQISVMLGPCAGGAAYSPALTDFVFMVRETSQMFITGPDVVKAVTGEEITQNGLGGAD
                     VHSTTSGVSHFAYDTEEECLEDVRYLLSLLPANNRELAPVERSGDPVDRVNDALLDLVP
                     AAAGQSYDIRAVIEEVVDDGEFFEVHPLWATNIVCAFARLDGHVVGIVANQPAAMAGVL
                     DIEASEKGARFVQFCDAFNIPLVTLVDVPGFLPGVDQEHDGIIRRGAKLLYAYCNATVP
                     RISLVLRKAYGGAYIVMDSRSIGADLALAWPTNEIAVMGAEGAANVIFRREINAAEDPE
                     AVRRQRIKEYKSELMHPYYAAERGLIDDVIDPRETRAVLIRSLEMLRAKHADLPSRKHG
                     NPPQ"
     misc_feature    32925..32938
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.28"
                     /tool="antismash"
     misc_feature    complement(34521..34535)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.29"
                     /tool="antismash"
     gene            34675..35004
                     /locus_tag="IE308_RS22870"
                     /old_locus_tag="GCM10018783_46560"
     CDS             34675..35004
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1225: Polyketide synthesis cyclase"
                     /gene_functions="biosynthetic-additional (t2pks) CYC
                     C4-C17/C2-C19 (Score: 198.3; E-value: 2.6e-61)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018383120.1"
                     /locus_tag="IE308_RS22870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46560"
                     /product="TcmI family type II polyketide cyclase"
                     /protein_id="WP_110627870.1"
                     /transl_table=11
                     /translation="MHSNLIVARMEPASGAQVAELFRAFDATEMPHLMGTRRRQLFHYR
                     GLYFHLQDFDTDNGGQQIEEAKTDPRFIRISEDLKPFIEAYDPATWRSPADAMATRFYH
                     WEAGS"
     gene            35001..36272
                     /locus_tag="IE308_RS22875"
                     /old_locus_tag="GCM10018783_46570"
     CDS             35001..36272
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (6-396). E-value:
                     3.3e-54. Score: 176.3. Matches aSDomain:
                     nrpspksdomains_IE308_RS22875_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_functions="biosynthetic-additional (t2pks) KS (Score:
                     784.3; E-value: 5.7e-239)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020141375.1"
                     /locus_tag="IE308_RS22875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46570"
                     /product="beta-ketoacyl synthase"
                     /protein_id="WP_110627869.1"
                     /sec_met_domain="t2ks (E-value: 1.2e-246, bitscore: 814.0,
                     seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 2e-53, bitscore:
                     177.1, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGRRVVITGLEVLAPGGVGTDAFWSLLSEGRTATRGITFFDPSP
                     FRSRVAAEIDFDPEAHGLSPQEIRRMDRAGQFAVVAARGAVADSGLDLTDHEAHRVGVT
                     VGTAVGATMGLDQEYRVVSDGGRLNLVDHHYAVPHLHNYLVPSSFAAEVAWAVGAEGAN
                     AVVSTGCTSGIDSVGYAVELIREGTADVMVAGATDAPISPITMACFDAIRATTPRHDEP
                     ERASRPFDSTRNGFVLGEGSAFFVLEELESARRRGARIYAEIAGYATRSNAYHMTGLRP
                     DGAEMAEAIRVSLDEARLNPEDIDYVNAHGSGTKQNDRHETAAFKKSLGEHAYRTPVSS
                     IKSMVGHSLGAIGAIEIAASTLAMTHHVVPPTANLHAPDPECDLDYVPLTAREHRTDAV
                     LTVGSGFGGFQSAMVLARPERTAA"
     aSDomain        35019..36188
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS22875_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="3.30E-54"
                     /label="IE308_RS22875_PKS_KS.1"
                     /locus_tag="IE308_RS22875"
                     /protein_end="396"
                     /protein_start="6"
                     /score="176.3"
                     /tool="antismash"
                     /translation="VITGLEVLAPGGVGTDAFWSLLSEGRTATRGITFFDPSPFRSRVA
                     AEIDFDPEAHGLSPQEIRRMDRAGQFAVVAARGAVADSGLDLTDHEAHRVGVTVGTAVG
                     ATMGLDQEYRVVSDGGRLNLVDHHYAVPHLHNYLVPSSFAAEVAWAVGAEGANAVVSTG
                     CTSGIDSVGYAVELIREGTADVMVAGATDAPISPITMACFDAIRATTPRHDEPERASRP
                     FDSTRNGFVLGEGSAFFVLEELESARRRGARIYAEIAGYATRSNAYHMTGLRPDGAEMA
                     EAIRVSLDEARLNPEDIDYVNAHGSGTKQNDRHETAAFKKSLGEHAYRTPVSSIKSMVG
                     HSLGAIGAIEIAASTLAMTHHVVPPTANLHAPDPECDLDYVPLTAREHRT"
     gene            36269..37483
                     /locus_tag="IE308_RS22880"
                     /old_locus_tag="GCM10018783_46580"
     CDS             36269..37483
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (51-402). E-value:
                     8.7e-35. Score: 112.3. Matches aSDomain:
                     nrpspksdomains_IE308_RS22880_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093: Beta-ketoacyl synthase"
                     /gene_functions="biosynthetic-additional (t2pks) CLF 8|9
                     (Score: 701.6; E-value: 5.9e-214)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037162.1"
                     /locus_tag="IE308_RS22880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46580"
                     /product="ketosynthase chain-length factor"
                     /protein_id="WP_110627868.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 8.9e-44, bitscore:
                     145.5, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="t2clf (E-value: 1e-206, bitscore: 682.0,
                     seeds: 26, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTSVVVTGLGVVAPNGLGAEEYWSAARVGKSGIGRLTRFDPTQY
                     PARLAGEIHGFEAEEYLPSKLLPQTDRMTRLALVAADWALEDAGVRPQELPAFDMGVVT
                     SSASGGFEFGQRELERLWSQGSEYVSAYQSFAWFYAVNSGQISIRHGMKGPSGVVVSEQ
                     AGGLDCLAQARRQVRKGTPLVVSGAVDASLCPWGWVAQMTSGRVTTSEDPAGAYVPFDD
                     RASGHVPGEGGALLVLEGKEAARARGAKVYGEIAGYGATFDPKPGSGRPSTLRKAIETA
                     LADAGVEARDVDVVFADGAAVPELDRIEAEALNEVFGTGQVAVTVPKTMTGALYSAAGA
                     LDVATVLLAMEEGLIPPTMNTEPAERYGLDLVAGHPRTTEVRTALVVARGQGGFNSALV
                     VRAAD"
     aSDomain        36422..37474
                     /ASF="found active site histidines: False"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS22880_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="8.70E-35"
                     /label="IE308_RS22880_PKS_KS.1"
                     /locus_tag="IE308_RS22880"
                     /protein_end="402"
                     /protein_start="51"
                     /score="112.3"
                     /tool="antismash"
                     /translation="EIHGFEAEEYLPSKLLPQTDRMTRLALVAADWALEDAGVRPQELP
                     AFDMGVVTSSASGGFEFGQRELERLWSQGSEYVSAYQSFAWFYAVNSGQISIRHGMKGP
                     SGVVVSEQAGGLDCLAQARRQVRKGTPLVVSGAVDASLCPWGWVAQMTSGRVTTSEDPA
                     GAYVPFDDRASGHVPGEGGALLVLEGKEAARARGAKVYGEIAGYGATFDPKPGSGRPST
                     LRKAIETALADAGVEARDVDVVFADGAAVPELDRIEAEALNEVFGTGQVAVTVPKTMTG
                     ALYSAAGALDVATVLLAMEEGLIPPTMNTEPAERYGLDLVAGHPRTTEVRTALVVARGQ
                     GGFNSALVVRA"
     CDS_motif       36926..36964
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS22880_0001"
                     /evalue="3.60E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="IE308_RS22880"
                     /protein_end="232"
                     /protein_start="219"
                     /score="10.7"
                     /tool="antismash"
                     /translation="FDDRASGHVPGEG"
     gene            38140..38403
                     /locus_tag="IE308_RS22885"
                     /old_locus_tag="GCM10018783_46590"
     CDS             38140..38403
                     /NRPS_PKS="Domain: ACP (13-82). E-value: 3.4e-13. Score:
                     41.7. Matches aSDomain: nrpspksdomains_IE308_RS22885_ACP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129: acyl carrier protein"
                     /gene_functions="biosynthetic-additional (t2pks) ACP
                     (Score: 123.4; E-value: 6.5e-39)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020141377.1"
                     /locus_tag="IE308_RS22885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46590"
                     /product="acyl carrier protein"
                     /protein_id="WP_110627867.1"
                     /sec_met_domain="PP-binding (E-value: 3.4e-08, bitscore:
                     29.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEQVFTLDDLRRILIEAAGDDESYNLDGDILDTEFEELGYESLA
                     LLETGGRIEREYGISLDEEVLSIANTPRLLIDTVNAGLAALV"
     aSDomain        38179..38385
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS22885_ACP.1"
                     /evalue="3.40E-13"
                     /label="IE308_RS22885_ACP.1"
                     /locus_tag="IE308_RS22885"
                     /protein_end="82"
                     /protein_start="13"
                     /score="41.7"
                     /tool="antismash"
                     /translation="ILIEAAGDDESYNLDGDILDTEFEELGYESLALLETGGRIEREYG
                     ISLDEEVLSIANTPRLLIDTVNAG"
     gene            38489..39274
                     /gene="fabG"
                     /locus_tag="IE308_RS22890"
                     /old_locus_tag="GCM10018783_46600"
     CDS             38489..39274
                     /EC_number="1.1.1.100"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (7-160). E-value: 1.9e-12. Score:
                     39.4. Matches aSDomain:
                     nrpspksdomains_IE308_RS22890_PKS_KR.1"
                     /codon_start=1
                     /gene="fabG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_functions="biosynthetic-additional (t2pks) KR C9
                     (Score: 489.3; E-value: 5.6e-150)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018103042.1"
                     /locus_tag="IE308_RS22890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46600"
                     /product="3-oxoacyl-ACP reductase FabG"
                     /protein_id="WP_110627866.1"
                     /sec_met_domain="adh_short (E-value: 2.4e-36, bitscore:
                     120.9, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEQEKRVALVTGATSGIGLASARLLAQQGHRVFIGARNADNVAA
                     TVKDLQAEGLEVDGATVDVRSGDEVRAFVQAAVDTFGTIDVLVNNAGRSGGGVTADIDD
                     ELWADVVETNLTSVFRVTREVLNTGGMRHKSRGRIINIASTAGKQGVVLGAPYSASKHG
                     VVGFTKALGNELAPTGITVNAVCPGYVETPMAQRVRQGYAAAYDTTEDAILEKFQAKIP
                     LGRYSTPEEVAGLVGYLASDTAASITAQALNVCGGLGNF"
     aSDomain        38510..38968
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS22890_PKS_KR.1"
                     /evalue="1.90E-12"
                     /label="IE308_RS22890_PKS_KR.1"
                     /locus_tag="IE308_RS22890"
                     /protein_end="160"
                     /protein_start="7"
                     /score="39.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VALVTGATSGIGLASARLLAQQGHRVFIGARNADNVAATVKDLQA
                     EGLEVDGATVDVRSGDEVRAFVQAAVDTFGTIDVLVNNAGRSGGGVTADIDDELWADVV
                     ETNLTSVFRVTREVLNTGGMRHKSRGRIINIASTAGKQGVVLGAPYSAS"
     CDS_motif       38516..38584
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS22890_0001"
                     /evalue="7.70E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE308_RS22890"
                     /protein_end="32"
                     /protein_start="9"
                     /score="21.8"
                     /tool="antismash"
                     /translation="LVTGATSGIGLASARLLAQQGHR"
     gene            39299..40234
                     /locus_tag="IE308_RS22895"
                     /old_locus_tag="GCM10018783_46610"
     CDS             39299..40234
                     /NRPS_PKS="Domain: Polyketide_cyc2 (4-146). E-value:
                     6.8e-14. Score: 44.4. Matches aSDomain:
                     nrpspksdomains_IE308_RS22895_Polyketide_cyc2.1"
                     /NRPS_PKS="Domain: Polyketide_cyc2 (155-308). E-value:
                     6.6e-11. Score: 34.7. Matches aSDomain:
                     nrpspksdomains_IE308_RS22895_Polyketide_cyc2.2"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128: cyclase/dehydrase"
                     /gene_functions="biosynthetic-additional (t2pks) CYC C7-C12
                     (Score: 515.6; E-value: 8.1e-158)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020141379.1"
                     /locus_tag="IE308_RS22895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46610"
                     /product="aromatase/cyclase"
                     /protein_id="WP_190219347.1"
                     /transl_table=11
                     /translation="MTIREVEHEITAKAPAETVYRLIAEVENWPRIFPPTIHVEHVERG
                     ERDERIRIWATANGEPKNWASRRTLDPDTLRIDFRQEVSTPPVAAMGGAWIIEPLSADE
                     CRIRLLHDYRAVDDDPAGLAWIDEAVDRNSRSELAALRTNVERAHAEADLTFSFEDSVE
                     IAGSAKDVYDFINEADLWAERLPHVASVRLTEDTPGLQTLEMDTRARDGSVHTTKSYRV
                     TFPHHKIAYKQVTLPALMTLHTGYWTFTETDTGVTASSQHTVTLNTANIARVLGEDATV
                     ADARAYVRDALSTNSRATLGHAKAHAEARR"
     aSDomain        39311..39736
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS22895_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="6.80E-14"
                     /label="IE308_RS22895_Polyketide_cyc2.1"
                     /locus_tag="IE308_RS22895"
                     /protein_end="146"
                     /protein_start="4"
                     /score="44.4"
                     /tool="antismash"
                     /translation="EVEHEITAKAPAETVYRLIAEVENWPRIFPPTIHVEHVERGERDE
                     RIRIWATANGEPKNWASRRTLDPDTLRIDFRQEVSTPPVAAMGGAWIIEPLSADECRIR
                     LLHDYRAVDDDPAGLAWIDEAVDRNSRSELAALRTNVE"
     aSModule        39311..40222
                     /domains="nrpspksdomains_IE308_RS22895_Polyketide_cyc2.1"
                     /domains="nrpspksdomains_IE308_RS22895_Polyketide_cyc2.2"
                     /incomplete
                     /locus_tags="IE308_RS22895"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        39764..40222
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS22895_Polyketide_cyc2.2"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="6.60E-11"
                     /label="IE308_RS22895_Polyketide_cyc2.2"
                     /locus_tag="IE308_RS22895"
                     /protein_end="308"
                     /protein_start="155"
                     /score="34.7"
                     /tool="antismash"
                     /translation="FSFEDSVEIAGSAKDVYDFINEADLWAERLPHVASVRLTEDTPGL
                     QTLEMDTRARDGSVHTTKSYRVTFPHHKIAYKQVTLPALMTLHTGYWTFTETDTGVTAS
                     SQHTVTLNTANIARVLGEDATVADARAYVRDALSTNSRATLGHAKAHAE"
     gene            40287..41105
                     /locus_tag="IE308_RS22900"
                     /old_locus_tag="GCM10018783_46620"
     CDS             40287..41105
                     /NRPS_PKS="Domain: ACPS (118-181). E-value: 1e-11. Score:
                     36.8. Matches aSDomain:
                     nrpspksdomains_IE308_RS22900_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020141380.1"
                     /locus_tag="IE308_RS22900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46620"
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="WP_229909001.1"
                     /transl_table=11
                     /translation="MLREAPELSLWLLRSPSPDSAAAARLAVRELDDTEVRRAALFVRP
                     ADRVQYLSAHIALRRILAATTGCPPESLRLGREPGPLLSPRTSRPVLRHPPVPVHFSLS
                     HSHGLILIGTAASAVGVDVQRTPTIEAVRVVGPALHPAEWRELLALPEPRRPAAFAQLW
                     TRKEAYLKGLGTGLVRGPALDYLGLGTDADAPPGPPGWIVRDVLVGPHHAAAAALAVAV
                     EPRITLRTLPVACLYDGDAGLPLSAAPLLALRRRGSWTLRWSLLERDPPG"
     aSDomain        40641..40829
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS22900_ACPS.1"
                     /evalue="1.00E-11"
                     /label="IE308_RS22900_ACPS.1"
                     /locus_tag="IE308_RS22900"
                     /protein_end="181"
                     /protein_start="118"
                     /score="36.8"
                     /tool="antismash"
                     /translation="VGVDVQRTPTIEAVRVVGPALHPAEWRELLALPEPRRPAAFAQLW
                     TRKEAYLKGLGTGLVRGP"
     gene            41060..42538
                     /locus_tag="IE308_RS22905"
                     /old_locus_tag="GCM10018783_46630"
     CDS             41060..42538
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 574.0; E-value: 6.2e-175)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511390.1"
                     /locus_tag="IE308_RS22905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46630"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_190219348.1"
                     /transl_table=11
                     /translation="MDASVVVVGAGPAGLMLAGELRLAGTDVTVLERHPRRTGESRGIG
                     LTIGTMEVFDQRGLLGRLGPYETSGMGHFGGVPLDMSVLGRAHEAARTVPQSVTEEALE
                     SWARDLGADIRRGHEFVSYEDTGDGLTVTVRHPGGEERIHTRYLVGCDGGRSSVRKAAG
                     FDFPGTAATTEMLLADVRGVDLEPRMTGQHVGGGFVMVAKLAGGIHRLIVGEHGIPPRR
                     RTEPPAFAEVADLWKRLTGEDVSHAEPVWVSAFGNATRQVTEYRRGRVLLAGDSAHVHL
                     PAGGQGMNTSVQDAHNLGWKLAAVLRGDTPEELLDTYHGERHEVGRALLANTRAQSLLV
                     LGGEEAQPLRDVLAELIAYPEVTRHLAAKVSGLDIRYDVGGGTHPLLGRRMPHLPVTTA
                     SGPTSSTALLRTGRGVLLDLEDNAVLRRRAHAWRDRVDVVTATPGALPEDSPLAGTAAV
                     LLRPDGYVAWAAPGSHRDLNSALTRWFGPGLGRR"
     gene            42538..44547
                     /locus_tag="IE308_RS22910"
                     /old_locus_tag="GCM10018783_46640"
     CDS             42538..44547
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 528.7; E-value: 3.4e-161)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432346.1"
                     /locus_tag="IE308_RS22910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46640"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_190219349.1"
                     /transl_table=11
                     /translation="MARQTPDADVLVVGAGPVGLFLAAELRAEGAHTVVLERLPEPTGE
                     SRASVLHARTMEIFADRGFLPKLGELPPVGAGHFGGLRLDLADAAPDHPYAGQWECLQY
                     HLEAELERHARDLGADIRRGHTLTGLSQSGDGVRAEVRRPDGTRYTLTAGYLAGCDGER
                     STVRDLAGFELAGHEADKVMLRADIAGVELDNRRLQRFPDGIATAYRRPDGTTRLMVHR
                     FGEQPAGEVTFEQVVTAWAAVTGEDIGHGRALWLNRFDNASRQVTEYRRGRVLLAGDAA
                     HQQMPVGGQAVNLGLQDAANLGWKLARVATGQARLALLDTYHAERHPVGARTLAHIRAQ
                     AHLLFGTEEVTALRDVFGELLEFAGVRRHLARAISGLDVTEQPRPDRPAEPAPHTGGRA
                     RPLRPHPSHTHPSGRSTVDRLTDKTALVTGSSRGIGRATAIRLAREGALVAVHYTANQA
                     AAEETVELIEKEGGSAFTVRAELGVPGDVHELFLGLERGLKERTGDTRLDILVNNAAVT
                     STGAAPEDLTPEEFDRYFAVNAKAPYFLVQRAIGQMPSGGRIVNITSGVTRTAVPDQLA
                     YAMTKGAIEQLTFHLARILAPRGITINSVAPGITDNGSALFDNPEAVKAMAQLSAFNRV
                     GEAGDVADVITFLTTDEARWITGAFIDATGGTLS"
     gene            44584..45348
                     /locus_tag="IE308_RS22915"
                     /old_locus_tag="GCM10018783_46650"
     CDS             44584..45348
                     /NRPS_PKS="Domain: PKS_KR (9-149). E-value: 1.9e-11. Score:
                     36.2. Matches aSDomain:
                     nrpspksdomains_IE308_RS22915_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_functions="biosynthetic-additional (t2pks) KR (Score:
                     145.4; E-value: 5.7e-45)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020141383.1"
                     /locus_tag="IE308_RS22915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46650"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_110627862.1"
                     /transl_table=11
                     /translation="MSAKTPRYAVVTGGNKGIGREIVRQLAERGLVVYLGARDEQRGRA
                     AESDLRADGLDVRFLHLDVTDDKSVALAAERLHEEAGVLHVLVNNAGIGGPMQPPSETP
                     TEQVRTVYETNVFGVITVTNALLPLLRRAGSARIVNVSSAIGSLSAAAANHDPTGVHPP
                     GEFPVMLSYATSKSALNAVTLTYANELRGTGILVNAASPGFVATDINGHHGVLTPQQGA
                     RIPVLLATLGDDGPTAAFLGEDGTPEGQVLPW"
     CDS_motif       44611..44673
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS22915_0001"
                     /evalue="6.80E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE308_RS22915"
                     /protein_end="30"
                     /protein_start="9"
                     /score="21.9"
                     /tool="antismash"
                     /translation="VVTGGNKGIGREIVRQLAERG"
     aSDomain        44611..45030
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS22915_PKS_KR.1"
                     /evalue="1.90E-11"
                     /label="IE308_RS22915_PKS_KR.1"
                     /locus_tag="IE308_RS22915"
                     /protein_end="149"
                     /protein_start="9"
                     /score="36.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VVTGGNKGIGREIVRQLAERGLVVYLGARDEQRGRAAESDLRADG
                     LDVRFLHLDVTDDKSVALAAERLHEEAGVLHVLVNNAGIGGPMQPPSETPTEQVRTVYE
                     TNVFGVITVTNALLPLLRRAGSARIVNVSSAIGSLS"
     gene            45345..46556
                     /locus_tag="IE308_RS22920"
                     /old_locus_tag="GCM10018783_46660"
     CDS             45345..46556
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432345.1"
                     /locus_tag="IE308_RS22920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46660"
                     /product="MFS transporter"
                     /protein_id="WP_190219350.1"
                     /transl_table=11
                     /translation="MTGALLDPPAVRAGWTARQWTRLLVLSGNMLLDAVEVSVVLIALP
                     AVAARYGLTPWGAQWLMSGFALGFAALLLLGPALCARIGRRRAYLGAMLLFVLASLAGG
                     VVDGPALLVAVRVVKGCCAALTAPMGLALINDLFPEGPERRRALSVYSLSGAAGFTAGL
                     LLAGALLASDWRWVFVFPAPVALVLLVCGLFVLPRGRGGTPPGPPRPALLKQGALLRSA
                     LGAASLNGTYQALLVLMVFQMHDDFGWSAWRTALALLPACVPLALTVPFAGRFIARYGT
                     RRLIAAGALFPLLGYGLCLARPDGSPYAVGTLPVLLLVEAGFCCAFVALNAQATAGFEA
                     ADRGAAVSLYQTCVQLGAAVLLPLVALLLTHGDGPRPALALITAVGALGLAAALAHRPA
                     RSGR"
     gene            46667..47698
                     /locus_tag="IE308_RS22925"
                     /old_locus_tag="GCM10018783_46670"
     CDS             46667..47698
                     /GO_function="GO:0008171 - O-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_functions="biosynthetic-additional (t2pks) MET
                     C2O|C2N (Score: 295.7; E-value: 9.4e-91)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020141385.1"
                     /locus_tag="IE308_RS22925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46670"
                     /product="methyltransferase"
                     /protein_id="WP_190219351.1"
                     /transl_table=11
                     /translation="MADVAHESAPNPGPIMGLILGAWQSRMLLAAVEHDIFTELSKGAA
                     TSAELAGRIGLVERPTNDLLAGLAHLGLLESADGTFTNSAVADAFLVRGRPAYLGGYLH
                     FCEQELNPAWNGLADSLRTGRPQNRAAVEGNPYDTLYADADATDGFLDSMDLLNAPIAA
                     ALSRFDWSGYTSFVDIGGARGNFAHQIVTHNPHLKGAVFDLPPLEPAFRRHMDRLGDTP
                     APITFHGGDFFKDDLPAADVLVFGHVLHNWGVDDRVTLLKRAYDALKPGGAVFVYDPMA
                     GGQQPSMHGALAGLTMLVWSRGGHEYTADELHGWLREAGFWPETVEVDGLHDDVLVIGR
                     KAE"
     gene            47725..48405
                     /locus_tag="IE308_RS22930"
                     /old_locus_tag="GCM10018783_46680"
     CDS             47725..48405
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE308_RS22930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10018783_46680"
                     /product="hypothetical protein"
                     /protein_id="WP_190219352.1"
                     /transl_table=11
                     /translation="MPRTSDTRPVLGRPDATAALVEEVVDGDPEKLRAATAAVLRHWDS
                     AEWPAGLLAVSLFTGTDDTSLLVYSQWSARAGHGDDLPAAFDALRPDWRALGYTPGEPR
                     VFELYRRVQPAVLPDPLPPVGCYPAAFFSMNDGQTARAWVDGLLGTEEETIGEDRAYPG
                     AIAANFHVSADDSGIFLLSEWASEAEALVHIKAEIEPLLEYMGQAEAGPGRRYTFHATA
                     ATAG"
     gene            48432..49349
                     /locus_tag="IE308_RS22935"
                     /old_locus_tag="GCM10018783_46690"
     CDS             48432..49349
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017241295.1"
                     /locus_tag="IE308_RS22935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46690"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_110627859.1"
                     /transl_table=11
                     /translation="MSTREVVFGFGAHSTIDQGPELLDMARLADREGLDLFSLSDHPYI
                     GQRLDAYATVGFVLGRTQRLAGFANVSNVPLRPPAMLARTVTTLSALSGGRVVLGFGAG
                     GLWERIADMGREPLTPGEAVEAFEEAVVLIRKLCGGGPPVTFEGRHYHVRQIEPAPVPA
                     PPVWTGSVGRKSLAATGRVADGWIPGHAADWLSPRYRASRPVIDEAAKAVGRDPREVRT
                     IFNFPGRITDRPLSVTRDPDGRWIGGSVEQWVEELTGAVLEHDAGGFMLFSPRGGTPDM
                     ASLGRWAGQIVPAVREAVARHRGQ"
     gene            49426..50193
                     /locus_tag="IE308_RS22940"
                     /old_locus_tag="GCM10018783_46700"
     CDS             49426..50193
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_functions="biosynthetic-additional (t2pks) KR C15
                     (Score: 381.1; E-value: 5.2e-117)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016573128.1"
                     /locus_tag="IE308_RS22940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46700"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_110627858.1"
                     /transl_table=11
                     /translation="MSRLKNKTALVTGASRGIGRGIALRLAQDGALVAVNYSANEAAAK
                     ETVALIEEAGGRAFTVQAELGKPGAVEQLLAGVEAGLVEHTGSRTLDILVNNAAATGFA
                     GTGPHSVTEEILDNCYNINAKAPFLLIQKALDLIPDGGHIVNVSSGVTHSAFPIQIAYA
                     MSKAALEQITLHMAPVLAPRNITINTVAPGITNNGDPVFEDPEAVKQMAALSVFNRVGE
                     VSEVADIVAFVASDEARWITGAFVDATGGTLLR"
     misc_feature    49436..49452
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.28"
                     /tool="antismash"
     gene            50204..50881
                     /locus_tag="IE308_RS22945"
                     /old_locus_tag="GCM10018783_46710"
     CDS             50204..50881
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020141389.1"
                     /locus_tag="IE308_RS22945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46710"
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="WP_190219353.1"
                     /sec_met_domain="PF07366 (E-value: 8e-06, bitscore: 21.3,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHNEIQSAVGYAHAKPEKAEELRDLLVSFAERSRAEEGCLGSWIN
                     QDAGDPHLFVFYEIWATRKDLARHLAQPYMKEFLAGRDEYLAKELEVRQLHLAGPAPEP
                     AEPADPAEMNQRYLDAYAARDIDAIMAVYAPGAAAVWEPGKAVSGAEHRAAVEEFLKRE
                     PKLSAEVRESYVVGDTAALVVDWSIEVPGSPEMTGTGRGLDVLRRNARGEWRYIITNPF
                     GSL"
     gene            50883..51671
                     /locus_tag="IE308_RS22950"
                     /old_locus_tag="GCM10018783_46720"
     CDS             50883..51671
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_functions="biosynthetic-additional (t2pks) KR (Score:
                     119.3; E-value: 5.1e-37)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020141390.1"
                     /locus_tag="IE308_RS22950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46720"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_110627856.1"
                     /transl_table=11
                     /translation="MRIEGSVAVVTGAASGIGKAIAEQLALAGARGVVVSDLDAEGAEK
                     VAAGIGSAALAVQADVGEEASVQALVARARERFGQVDIFVSNAGLTVTGSYDAPDEDWK
                     RAMIVNMMSHVYAARAVLPAMLEAGRGHLVQTIAACGVLTAFGAAPYVVAKQGAVAFAE
                     YLAVEYGDRGIGVSCLLPQAVNTPMLAASVSSNEQLAQLKKNSEVLEPEDVARAALAGI
                     EENRLHVFTHKGSAESFRQRAADADVWAAQMRAIRHGGRP"
     misc_feature    51849..51864
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.07"
                     /tool="antismash"
     misc_feature    51851..51865
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            51859..52440
                     /locus_tag="IE308_RS22955"
                     /old_locus_tag="GCM10018783_46730"
     CDS             51859..52440
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020141391.1"
                     /locus_tag="IE308_RS22955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46730"
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="WP_110627855.1"
                     /transl_table=11
                     /translation="MSEENLQLTVIIGSSREGRTGPAVARWFVAEAESCAMFDVDVLDL
                     AGVELPLSLTQDPGSESAELLAAVGARLESADAFVVITPEYNHSFTAPMKNLIDWHRTP
                     WQAKPIGFVSYGGLSGGLRAVEQLRQVFAELHAATIRDTVSFHGVWQHVGEDGVLRAPD
                     AAVPAKVMLEKLQWWAAALKDARTLRPYAA"
     misc_feature    complement(51860..51874)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.9"
                     /tool="antismash"
     misc_feature    51887..51901
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.48"
                     /tool="antismash"
     gene            52466..53815
                     /locus_tag="IE308_RS22960"
                     /old_locus_tag="GCM10018783_46740"
     CDS             52466..53815
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020141392.1"
                     /locus_tag="IE308_RS22960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46740"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_190219354.1"
                     /transl_table=11
                     /translation="MDKQIRVTAFAMNTPTHLSPGTWRHPASQGRRYKDLSYWTDLART
                     LERGLFDGLFIADVLGAYDVYAGTPDAALRGGAQVPVNDPMMLVSAIAHVTRHLGIAVT
                     ASTSYEHPYPFARRMSTLDHLTGGRVAWNIVTSYLDSAARNIGLDRQVGHDERYDIADE
                     YLEVVYKLWQGSWEDDAVRADDHYADPAKIHPIAHEGRWFTVPGIHLCEPSPQRTPLLF
                     QAGTSHRGKDFAARHAEAVFAVAPEAAMLRKQVEDLRGRVAAAGRDPHDIKVFSGCTVI
                     TGETEAEARAKYDEYRSHIDPEGMLALFSGWLGFDLSPYGLDDPVRVVPNHAVQSIAET
                     LGQGDWTVRDLLERLALGHPPVIVGAPDKVADEIQQWIEETGADGLNLGHVVTPSTYED
                     FVDLIVPELQRRGAYKTQYADGTLRHKFFGRGDRPALTHPGSRYTHAALD"
     misc_feature    53820..53833
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.12"
                     /tool="antismash"
     misc_feature    complement(53820..53834)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.77"
                     /tool="antismash"
     gene            53825..54454
                     /locus_tag="IE308_RS22965"
                     /old_locus_tag="GCM10018783_46750"
     CDS             53825..54454
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020141393.1"
                     /locus_tag="IE308_RS22965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46750"
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="WP_110627853.1"
                     /transl_table=11
                     /translation="MSSIRVEDGYFTLFNIFHTDGPEAQQLLFDQWRSLPPAHTQPGLV
                     SGNFHRGFDGASVVNYAQWESRAAYDAFMSEQATRGRLGSALAVSRLDSIACEVVHTWD
                     PAPRISLDQPWYTVVVVVKSAPEDQAEVLKEMTFDPPELADTPGYVSHAVHRGLSGEHV
                     VKYAQWRDEESFRAFVSRPQEPSPLDELSVEVELYFGEIEYIRERS"
     misc_feature    53865..53880
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.77"
                     /tool="antismash"
     gene            54451..55758
                     /locus_tag="IE308_RS22970"
                     /old_locus_tag="GCM10018783_46760"
     CDS             54451..55758
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191: acyl-CoA dehydrogenase type 2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020141394.1"
                     /locus_tag="IE308_RS22970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46760"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_190219355.1"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2e-07, bitscore:
                     26.9, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTATWPDARALQTAADTAARHAAEADTGGRLADATVRALAEAG
                     FTAGFAPVGQGGAGATFTRMTDAVAAIGEGCTSAAWIASLWAYNGRFSAYLPEEGQREV
                     WAKGPDTRLVSSMVAAGVEAEPVDGGWRISGSWLYVSGVEFADWALVSSAPPREGDRTI
                     RVFAVPRDSFTYRETWSTLGMRATGSHTLVVEEAFVPEYRSFLWDDMRQGNLPVPAANS
                     GHDGADGSHIRPNSGTPSSAGAGSFSGPASASLSATPSGSATGPLSGAESGSLSGADAV
                     SAVHSAPLFAVNGLTFAAPILGAARQALRLVEEHLAQQPSGARAAARESHRIALARAAG
                     EIDAAALLLARVADTADRGLLREDGVAVRSHRDSTLAVELLVGAVDRLFRVTGTRGQAT
                     SHAMQRIWRDVHGAGSHAALQFEPAALAYTQRLVAA"
     gene            complement(55766..56215)
                     /locus_tag="IE308_RS22975"
                     /old_locus_tag="GCM10018783_46770"
     CDS             complement(55766..56215)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552791.1"
                     /locus_tag="IE308_RS22975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46770"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_110627851.1"
                     /transl_table=11
                     /translation="MGLVAALVRSSFLVHAVYAQAARDDGLTPQQGQLLCVLMAQPYGM
                     GELCSMLGLAKSSLTGLVDRTENNGLVRREPDPRDSRAVRVALTPRGARLADRFYTEAC
                     RRIEELPAGLDPAERDTLAGLLGRIVLDHKVPAVFAEPDQASPGG"
     misc_feature    56293..56307
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.5"
                     /tool="antismash"
     misc_feature    complement(56303..56317)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.48"
                     /tool="antismash"
     misc_feature    56321..56337
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.09"
                     /tool="antismash"
     gene            56442..57542
                     /locus_tag="IE308_RS22980"
                     /old_locus_tag="GCM10018783_46780"
     CDS             56442..57542
                     /EC_number="1.6.5.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_functions="biosynthetic-additional (t2pks) DIMER
                     (Score: 296.3; E-value: 5.2e-91)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020141396.1"
                     /locus_tag="IE308_RS22980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46780"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_190219356.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 7.9e-39, bitscore:
                     129.2, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRTVAVVGGGYGGAAVAKALESEADVVLIDPRDAFVNVAGSLRA
                     VTQPDWAANMFYPFSTLLTKGKLVRDRAVSVDPAGVTLSSGERVAADYVVLATGSNYPY
                     PANPTADTVTEALEDFRRSHKELRQADRILILGAGPVGLELAGEIKEIWPDKKVTIVDP
                     ATELLPGFKPEVVEDLRGQLDALGVEVRLGNSLTAQPGTEAGVAGSFTVTTTDGDEITA
                     DVWYRAYGTTVNSGYLSDGKLTTLTPAGQVEVTEKLNVKGYDHVYAIGDLTDVAENKMA
                     GFAMQHAEVVAKNIIAQIKGEEPTATYQPLGFPMILLPLGTKGGVGQLPSPDGPFVAPA
                     SMVSEFKGSDLFTGRFVGQFGPTAAS"
     gene            58029..58283
                     /locus_tag="IE308_RS22985"
                     /old_locus_tag="GCM10018783_46790"
     CDS             58029..58283
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018562056.1"
                     /locus_tag="IE308_RS22985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46790"
                     /product="acyl-CoA carboxylase subunit epsilon"
                     /protein_id="WP_190219357.1"
                     /transl_table=11
                     /translation="MSPSASADHTAVPASAETFLRIEKGSPDATELAALTSVLLARAAV
                     LANADEETEQTPRRTAGWRRLERRSRAGTPRSWRDDTRR"
     gene            58358..59278
                     /locus_tag="IE308_RS22990"
                     /old_locus_tag="GCM10018783_46800"
     CDS             58358..59278
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (38-137). E-value:
                     4.4e-11. Score: 34.8. Matches aSDomain:
                     nrpspksdomains_IE308_RS22990_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015610263.1"
                     /locus_tag="IE308_RS22990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46800"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_190219358.1"
                     /sec_met_domain="PF00561 (E-value: 5.6e-08, bitscore: 28.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 5e-12, bitscore:
                     42.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQPSPADASPVRDITLDADGIPLSGLLAEARHGPPRAVVVAVHG
                     GGMSAGYFHSQVRPGLSLLTLGADLGYTVLAIDRPGYGSSAAWLPRGQTLADQAATFHD
                     ALESFAATHDTGAGLFVVAHSNGGKLALAAAAEERGGTLLGLDISGLGCRLAVRRDQLP
                     GLNGHGDWRRHWGSLRLYPPDAFRQGRHLISPVPELEAQEGPSWPRMYPDIARRVRTPV
                     RFTFAEQEQWWRFDDEAVAALREPLVAPKVLVDHQPDAGHNLSLGWAARTYHLKALGFL
                     EDCLLARDAAPAHPRLRQREPIAAS"
     aSDomain        58472..58768
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS22990_Abhydrolase_1.1"
                     /evalue="4.40E-11"
                     /label="IE308_RS22990_Abhydrolase_1.1"
                     /locus_tag="IE308_RS22990"
                     /protein_end="137"
                     /protein_start="38"
                     /score="34.8"
                     /tool="antismash"
                     /translation="VVVAVHGGGMSAGYFHSQVRPGLSLLTLGADLGYTVLAIDRPGYG
                     SSAAWLPRGQTLADQAATFHDALESFAATHDTGAGLFVVAHSNGGKLALAAAAE"
     gene            59403..59561
                     /locus_tag="IE308_RS22995"
                     /old_locus_tag="GCM10018783_46810"
     CDS             59403..59561
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE308_RS22995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10018783_46810"
                     /product="hypothetical protein"
                     /protein_id="WP_162655497.1"
                     /transl_table=11
                     /translation="MTIDTLEPELVSHRQTPDEPQPVAAQPVVVRPALLAGEEHEAPDP
                     WIFRGTD"
     misc_feature    complement(59409..59423)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     gene            59627..60835
                     /gene="metK"
                     /locus_tag="IE308_RS23000"
                     /old_locus_tag="GCM10018783_46820"
     CDS             59627..60835
                     /EC_number="2.5.1.6"
                     /GO_function="GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="metK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009187586.1"
                     /locus_tag="IE308_RS23000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46820"
                     /product="methionine adenosyltransferase"
                     /protein_id="WP_190219359.1"
                     /transl_table=11
                     /translation="MSRRLFTSESVTEGHPDKIADQISDAILDELLRQDPTSRVAVETL
                     ITTGQVHIAGEVTTAGYADIAALVRETILRIGYDSSAKGFDGASCGVSVSLGAQSPDIA
                     QGVDAAYEARVEGDDDELDKQGAGDQGLMFGYATDETPTLMPLPIELAHRLSRRLAEVR
                     KDGTLPYLRPDGKTQVTIEYLGNRPVRLDTVVVSSQHAPGIDLDGLLVPDIRTHVVEPV
                     LNALAEDDIKLETEDHRLLVNPTGRFEIGGPMGDAGLTGRKIIIDTYGGYARHGGGAFS
                     GKDPSKVDRSAAYAMRWVAKNVVAAGLASRCEVQVAYAIGKAEPVGLFVETFGTGTVAQ
                     ERIERAIAEVFDLRPAAIIRDLDLLRPIYAQTAAYGHFGRELPDFTWERTDRAEALKAA
                     AGV"
     gene            60927..61910
                     /locus_tag="IE308_RS23005"
                     /old_locus_tag="GCM10018783_46830"
     CDS             60927..61910
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018555414.1"
                     /locus_tag="IE308_RS23005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46830"
                     /product="carbohydrate kinase family protein"
                     /protein_id="WP_190219360.1"
                     /transl_table=11
                     /translation="MRIAVTGSIATDHLMVFPGRFADQLLPDRLARVSLSFLVDALEVR
                     RGGVAANIAYGLGSLGLDPLLVGAVGSDFAEYAVWLKDHGVDTGAVQISAERATARFMC
                     ITDEDANQIASFYAGAMQEARDIDLGRVLAGRPLPDLVLVGPNDPEAMLRHTRECRALG
                     LSFAADPSQQLARLTGAQARDLVTGARWLFTNEYEAALLLERTGWDHDDVLTRVGAWIT
                     TLGGDGVRVESAGEPPLTVPAVPDTPVTDPTGVGDAFRAGFLAALSRRLPLPAAARLGC
                     VVASAALATVGSQAYRIDPEHLLTTAARAYGADAARELAPALDGTP"
     gene            61907..65374
                     /gene="metH"
                     /locus_tag="IE308_RS23010"
                     /old_locus_tag="GCM10018783_46840"
     CDS             61907..65374
                     /EC_number="2.1.1.13"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0008705 - methionine synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0031419 - cobalamin binding [Evidence
                     IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004946263.1"
                     /locus_tag="IE308_RS23010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46840"
                     /product="methionine synthase"
                     /protein_id="WP_190219361.1"
                     /transl_table=11
                     /translation="MTPSRSADLREALATRVVVADGAMGTMLQAQEPSMEDFQQLEGCN
                     EVLNVTRPDIVRSVHAAYFDAGVDCVETNTFGANHAALGEYGITERIFELSEAGARIAR
                     ETADDFTRRTGRQRWVLGSMGPGTKLPTLGHTTFAAIRDAYQRNAEGLVTGGADALLVE
                     TAQDLLQAKAALLGARRALDALGADLPLICSVTVETTGTMLLGSEIGAALTALEPLGID
                     MIGLNCATGPAEMSEHLRHLSHHAGILLSCMPNAGLPALTKEGARYPLTPAELADAQEG
                     FVREYGVSLVGGCCGTTPEHLRQVVERVRGLSPAERDPRPEPGAASLYQSVPFRQDTSY
                     LAIGERTNANGSKKFREAMLEGRWDDCVEMAREQIREGAHMLDLCVDYVGRDGVADMEE
                     LAGRFATASTLPVVLDSTEVEVIRAGLEKLGGRAVINSVNYEDGDGPESRFARVTALAR
                     EHGAALIALTIDEEGQARTAEKKVEIAERLIADLTGNWGIREEDILVDCLTFTICTGQE
                     ESRKDGIATIEGIRELKRRHPNVQTTLGLSNISFGLNPAARILLNSVFLDECVKAGLDS
                     AIVHASKILPIARFDEEQVQTALDLIYDRRREGYDPLQKLMQLFEGATAKSLKASKAQE
                     LAALPLEERLKRRIIDGEKNGLEADLDEALAARPALEIVNEVLLDGMKVVGELFGSGQM
                     QLPFVLQSAEVMKTAVAYLEPHMEKTDEAGKGTIVLATVRGDVHDIGKNLVDIILSNNG
                     YNVVNLGIKQPVSAILEAAQEHNADVIGMSGLLVKSTVIMKENLEELNARGLAADYPVI
                     LGGAALTRAYVEQDLHEIYQGEVRYARDAFEGLRLMDALIGVKRGVPGAVLPELKQRRV
                     RPTAQAVVEERPEEGHVRSDVATDNPVPAPPFFGTRVIKGIQLKEYASWLDETALFRGQ
                     WGLTKDLVETEGRPRLRGLLDRLQTENLLEAAVVYGYFRCVSKNDDLIILDEAGNERTR
                     FTFPRQRRGRRLCLADFFRPEESGETDVVGLQVVTVGSRIGEETARLFEADAYREYLEL
                     HGLSVQLAEALAEYWHARVRQELGIAGADPDALDGMFRTEYQGCRYSLGYPACPDLEDR
                     AKIAELLQPERIGVHLSEEFQLHPEQSTDAIVVHHPEAGYFNAGGGRA"
     gene            65371..66228
                     /gene="metF"
                     /locus_tag="IE308_RS23015"
                     /old_locus_tag="GCM10018783_46850"
     CDS             65371..66228
                     /EC_number="1.5.1.20"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014050047.1"
                     /locus_tag="IE308_RS23015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_46850"
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_110627844.1"
                     /transl_table=11
                     /translation="MTTFSFEFFPPKSEQGERVLWEAIRRVETLHPDFVSVTYGAGGSS
                     RDRTVAVTRRIAAETTLRPVAHLTAVGHSVAELRHIIGQYADAGVRDVLALRGDPPGDP
                     KGPWTPHPDGFTHAWQLVELVRSLGDFTIGVAAFPEMHPRSPDWESDIRHFVAKCRAGA
                     DYAITQMFFHVEDYLRLRDRVAAAGCDIPIIPEIMPATDYRQIRRFAELSDAAFPEDLA
                     RRLHAARGNPAAGHRIGVEYATAMAERLLAEGAPGLHYITLNKSTAALDIHRTLQIPRS
                     VSVR"
     gene            66218..>67331
                     /gene="ahcY"
                     /locus_tag="IE308_RS23020"
     CDS             66218..>67331
                     /EC_number="3.13.2.1"
                     /GO_function="GO:0004013 - adenosylhomocysteinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ahcY"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015035281.1"
                     /locus_tag="IE308_RS23020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="adenosylhomocysteinase"
                     /protein_id="WP_190219362.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 7.1e-11, bitscore:
                     37.3, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSADFTDFKVADLSLAEFGRKEITLAEHEMPGLMAIRKEYAEAQP
                     LKGARITGSLHMTVQTAVLIETLVALGAQVRWASCNIFSTQDHAAAAIAAAGIPVFAWK
                     GETLEEYWWCTEQALTWPNTPTGGPNMILDDGGDATLLVHKGVEYQKTGELPPADNEEL
                     AVVRALLEAGTLDWTQLASEIRGVTEETTTGVHRLYEMQRDGVLLFPAINVNDAVTKSK
                     FDNKYGCRHSLIDGINRATDVLIGGKTAVVCGYGDVGKGCAESLRGQGARVIVTEIDPI
                     CALQAAMDGYQVTTLDEVIDKADIFITTTGNKDIIMASDMAKMKHQAIVGNIGHFDNEI
                     DMAGLAKIPGIVKDEVKPQVHTWTFPDGKVI"
ORIGIN
        1 tcccggcgat gcgggcgccc aggtcctggg agggcccgac gatgggccgg gtgtcggcgg
       61 cgcccgcgtg cacggcctcg ggcaggatga cgtggaagcc gcggttgccg gcggccgagc
      121 cgtcggcgtg gatcgacacg acggcgtccg cgtgcgcggt gttcccgatg cgggcccgct
      181 cgtccacgca cggcccgtac ggtcggtccc cgtcctgcgt cagtttcacc gtggcgccct
      241 gccgttgcag caggtcacgg aggcggtggg cgacgtcgag ggtgaaacgg gcctcggtgt
      301 agccggagtt ggtggacgtg ccggtggtgt cgcactcctt gcggttggtg ccgatgtcca
      361 cctggcggtt gatggcggcc gtgtgccgga agttgcccgg gttgtggccg gggtcgatga
      421 cgacgacctt gcccgcgagc ggaccccggg cggcggcccg ggaccggctg ggcgacggac
      481 tcgccgcggg cgccgtaccg gccgtgggcg gcgtaccggc cgtaggcgac gtgccggccg
      541 tcggcttctt gccgtcgtcc cgggcggacg cggaagcgga cggcgagccg ggcgcgctga
      601 cggcggcccc gcccgcgtca ccgggggcgc ccaccgccgc gtacaccgcc cagcccagca
      661 gggcgcccgg cacgagcgcg gcgagcgcca cgacgagggg gcggcggcgg ggacggcggg
      721 gctgcggggg atcgaagtcc gggcctacgt acgacacggc agccacccta gccgccggtc
      781 agcggtgtgg caggccaccg gtcgggggcg ggtgcccgcg gccccggttt catccgaacg
      841 gcacgccggc gtcgcccgaa gccgggcgat gtgcccaaaa tcgcggtggt tcaccgcttt
      901 tgtcctccgc ttgatcacca gcaaaggaga acactcatgc gcgtcatcac cagagtcctc
      961 gccgccaccg ccatcgccgg actgacggtc ctgggcacgt ccgcggcggc gcaggccgcc
     1021 ccggccggca ccgacggtgc cctgtcccat ccgtgcgacg acagcggcgc gtgcgccgtg
     1081 ggcaccgcga tcggctcgcc cggcgtcctg tccggcaacg tcatccagat cccgatcgac
     1141 ctcgacgtca acgcctgcgg caactcgatc aacgtggtcg gcctgctcaa cccggcgttc
     1201 ggcaacacct gcgtcaacga ctgagcggga gccgtcccgt acgtcagatc ccggccccgg
     1261 tccgcctcag cacccgcagc gacccggtcg ccgacacctc cgtgaacgcg ccggactcca
     1321 gcgcccgcag gtagacgcgg tagggcgcct ggccggtgaa ctcgtcgacg gggtcgggga
     1381 agacgtcgtg gatgacgagc acgccaccct cggcgacatg cggggcccag ccctcgtagt
     1441 cggcggtggc gtgctcgtcg gtgtgcccgc cgtcgacgaa caccagcccg accggcgccg
     1501 cccacacctt cgccacctgc ggcgaccgcc cgacgaccgc gacgacgtgc tgctcaaggc
     1561 ccgccttgtg cagggtccgg cggaaggtgg gcagcgtgtc catcagcccg acctccgggt
     1621 cgacggtctc cgggtcgtgg tactcccacc ccggctgctg ctcctcgctg ccgcggtggt
     1681 ggtcgacggt caccgcgacg acgccggccg cccgcgcggc atctgcgagc aggatcgtcg
     1741 accgcccgca gtacgtcccc acctccagca acggcagccc gagccgcccg gcggccacag
     1801 cggcgtcgta gagcgcgagc ccctcgtcca cgggcatgaa ccccttggcg gcctcgaacg
     1861 cggccagaat ctcgggcttg ggggcggcgg gcatagcagg ggcgccttcc ggtcgtacgg
     1921 cactgcggac gccccacatg ctgccgcacc cccggccgaa cttgtcggca gggggtgcgg
     1981 tgatgtccct gaaggggcgc ggggaactgc gcgaccagcc cgaacggccg ggaagccgcc
     2041 gaaccgcatc ggcgaccggc ccctcaggcg cgcacagcct ccccaggcaa cgaaagatcc
     2101 agctcgacag cgcgctcgtc cccggcatgc gtggcggaag aagcgtgcgg accatggccg
     2161 gaggccttcg ccgcgacgac atacggcccc ccggacggca ccgccagcac gtaccgcccc
     2221 tcctcgtcgg agagggcgga gccggcccgc cgtccccgcc ggtcgatcag cgtgaccttg
     2281 gcccgggcga cgggcgcccc gccggcgtcc agcacgcgcc cgcggaagcc ccgcaggacc
     2341 tcctcggcgc gctccaggtt ggcctcctcc tcgctgctgg cccgcagccg cggggcccgg
     2401 tccggcttcg gcaggaacag cgccatgagc aggccgacgg cgaccgcggc cgtggcgatg
     2461 aggaaggaga cacggaagcc gtgcatggtc ggcacggcca ccccgcccac gtggtccgcg
     2521 gtgttcgcca gcaccatgcc gatgacggcg ctggagacgg acgtaccgat ggaccgcatc
     2581 agcgtgttca ggccgttcgc cgcgcccgtc tccgaggccg ggaccgcgcc gacgatcagc
     2641 gcgggcagcg aggagtaggc gaggccgatg cccacgccga ggacgacgga ggtgagcacc
     2701 gtctgccagg cggcgtccat caggccgagg ccgccgccgt agccgacggc gatgaccagc
     2761 aggccgatga tgagggtggc cttggggccg tacctggcgg acagacgggc gtacaccggc
     2821 gcggtgaaca tcatggtcag gcccagcggg gccacgcaca gaccggcgac gaccatcgac
     2881 tgcccgaggc cgtagccggt ggcggtgggc agctggagca gctggggcag gaccagggag
     2941 acgacgtaga agctgacgcc gaccatgatc gaggccaggt tggtgagcag cacctcgcgg
     3001 cgggcggtgg tgcgcaggtc gacgagcggg gccttggtgc gcagctcgac gacgccccac
     3061 ccgagcagca ccacgaccgc cgcggcgaac agggcgagcg tggtgccgga ggaccagccc
     3121 cagtcgctgc ccttggtgat cggcagcagc aggagcacca ggccggccga gaggccgagc
     3181 gcgccgggca ggtcgaagga gccctcggcg cgcatcgggg actccggtac gacgaggagg
     3241 gtgaggacga tggagagcac gccgagaccg gcggcgccgt agaagagggc gtgccagtcg
     3301 gtgtgctggg cgaccagggc cgcggcgggg agcgcgaggc cgccgccgac gccgatggac
     3361 gaactcatca gtgccatcgc cgagccgagc ttctcgcgcg gcagcatgtc gcgcatcagg
     3421 ccgatgccga gcgggatcgc gcccatcgcg aagccctgga gggtacggcc gccgatcatc
     3481 agcagcaggt tgctggtgac cgcgctgacc agggcgccgg ccaccatcac cgcgagactg
     3541 aggatcagca tccgccgctt gccgtacagg tcaccgaggc ggcccatgat cggggtcgcg
     3601 acggcgccgg agaggagggt cgaggtgagg acccaggtgg cgttgctggg cgaggtgccc
     3661 agcagctgcg gcaggtcctt gatgaccggt acgagcaggg tctgcatcac cgcgaccacg
     3721 atgcccgcga aggcgagcac ggggacgacg gcggccccgc cctctctggg ggcgggccgg
     3781 tcggtcgacg tgagcgtcat ggagtggggc ctccaggcca ggatcttttc ggtatgtgca
     3841 gcctgaacct cgtatgcacg ggcaactatt ccgttgcttc gagcccctaa cgaatccttg
     3901 accgtctctt gacgaaaaga cctaggaccg cggaccggca cccgcgtcgg acgaaaaccc
     3961 gatgcaaggg tcacagagcc actgagacca tgactcgcat gctcgacgcc gcagacgccg
     4021 ccgcccgcgc cccccgccgc ccggccccgc ccgcctggct ggtggtcacc ctggcctgcg
     4081 ccggacagtt cctcgtcgtc ctcgacgtgt cggtcgtcaa cacggccctg ccgtcgatgc
     4141 gcgccgacct cggactgagc gactccgggc tccagtgggt ggtcaacgcc tacgccatcg
     4201 ccttcgccgg tttcatgctg ctcggcggcc gggccggaga cctctacggc cgcaagcgca
     4261 tgttcctggt cggcctcgcc ctgttcaccc tcgcttccct cggcggcggc ctcgcccagg
     4321 acggctggca actgctgctc gcccgggccg tgcaggggct cggcgcggcc gtactggcgc
     4381 cctccaccct gacgctcctc accgccgccg tgcccgaggg ccccgcccgc gcccgggcca
     4441 tcgcgacctg gacagcggtc ggcggaggcg gcggcgccgc gggcggcctc gtcggcggcg
     4501 tcctggtcga cgcgctgtcc tggcgctggg tgctgctgat caacgtgccc atcggcgcgg
     4561 tcgtcctgct cggcgccctg cgctggctgc cggagagccg cgccggggac cgccgccgcc
     4621 tcgacctgcc gggcgcggtc ctggtgacgg ccgggctcgc caccgtcgcc tacggcatct
     4681 cgcagaccga gtccgagggc tggaccgcgc aggcgaccct gctgccgctc gcggccgggg
     4741 ccgcgctgat cgcgctgttc ctcgccgtcg aggcgcgcac ggccgccccg ctcatgccgc
     4801 tgcggctgct gcggctgcgg tcggtggcct ccgccaacac cgcgatgttc ctcagcggcg
     4861 ccgccatgtt ctgcatgtgg ttcttcatga cgctctacgc ccagaacgtc ctcggctaca
     4921 gcccgctgga ggccggcgtc gccctcgtcc ccagctccct cgccgtcgtc ctcggctcca
     4981 aactggcccc acgcttcatg ccggtggccg gaccgcgagt cgtcgccgtc ctgggaacgc
     5041 tcgtcgcggc ggccggcttc ggctggcagt cgacgatgag cgcgcacggc gactacgtca
     5101 ccgggatcct cgtgcccggc gtcctgatga tgctcggcgc gggcctggcg gccaccccgc
     5161 tcgcctccct cgccacctcg ggcgcggccc ccgaggaggc cggactggtc tccggcctcg
     5221 tcaacacctc ccgcacgatg ggcggctcgc tcggcctcgc cgtgatgtcc accatcgcgg
     5281 cggcccgcac ggcgggcagc accacaccgc aggccctgac cgacggctac gccctggcct
     5341 tccgcgcctc cacggccgtc ctgctgaccg gcgccgtgct gatgctgctg tggctgccgc
     5401 gtccgccgcg caccgcgccc gccggggcgg ccgtcccgca gaaggcggga aattcgtccg
     5461 cgagatgagg caacggtccg ggccgcccat ggactcctct tgatatccag gaggtgccca
     5521 tgggggatcg gaaacaggcc ggggacgagg agttccgggc ctttgtagca ggccgctggc
     5581 cgcggctgat gcgtacggca tttctcctca cgggggagca gcacgccgca gaggacttgg
     5641 tccagtcgac cctggaaaag gcctacgtgg cctggcgcag ggtcggctcg gccgacgacc
     5701 cggaggcgta tgtacgacgc gtcatgatca acacgcacgc gcgcagacac cgccggaaac
     5761 tacgggagtt cctcgcaccc cgcgacgact cggggatcgc ccgcgaggtg cccgacagcg
     5821 gtgaccacat ctcccgcgcc gaggaccgcg gcctgctgct gcaggccctc gcccaactgc
     5881 ccccgcggca gcggcaggcg gtcgtcctgc gctactggga ggacctcacc gagacccagg
     5941 ccgcggaggc catgggctgc tcggtcggcg cggtgaagag caatacggcc aaggggatcg
     6001 cgaaactgcg cgccataccg gaactggcgg acacggtgat gtacggaggg cggaagtgac
     6061 caacgcgaac cgggagttcg accacggcat gacggaccgg gacatcgcct tcctgctcgc
     6121 cgacgcggcg agcgccgtcg agatcggtac ggccccgacc caggcggtga tccgcggcgg
     6181 ccgccgccgc agagcccgcc gctgggcggt caccgccgcc accgccgccc tggtggcggg
     6241 ctccaccggc gccctcgcgg tgaccgcgct gcccggcgac ggcggccacc gggtggcccc
     6301 ggcgaccccg cccgcgacga gcgccacgcc gggcccggtg ctgcaacccg accccaccac
     6361 cctggccacc ggcaccgacc agggcacgcc ctggaaggtc accctcgacg tgtggcccgc
     6421 cccgcgcgac gagaccgagg cccagaccct gctgggcgcg atgacgacgt acggcgagtt
     6481 cccggccgac gtccacaagg cgtccgacct ggtcggcaga agcgcctaca ccgtccgcca
     6541 gagccacggc gacggcgaca cgctcggcac gcccgtcagc gagggcctga ccgcaccggc
     6601 cgaccgcatg gccggcaccg acctcgactc cgtcgcggtc cccctggacc cggacacccc
     6661 cggccgcccc cagcgcctgg tcgtcggcca cgtcgcccgc accgcccagg aggtgacctg
     6721 cacctggaag aacggcacca ccaccaaggt ccaccgggcc acgagcaccg acatcaactc
     6781 cgacgaccag accatccgca cacccgccac ctccccctac gcctggttcg tgtgcctggc
     6841 ccccgacggg acggccttcg agtcggtggc ggtgacgcgg taggggaggc gacggagggg
     6901 ggaggcgcag cgcggcccgc cctccggacg gacgacgcga cgttgcgggc gcggcctaga
     6961 gccacccctg gcggcgggcc tcgcgcatgg cctccatgcg gttgcgggtg ccggtcttgc
     7021 cgatggcgga ggagaggtag ttgcggaccg tggactcgga caggtgcagc cgggcggcga
     7081 tgtcggcgac ggtcgcgccg tcggcggagg cccgcagggc gtcgcactcg cgggcggtga
     7141 gcgggttcgg accggcgctg agcgcggcgg cggccagggc cgggtcgatc accgtctccc
     7201 cggtcagcac ccggcggatc gccacggcca gctcctccac gggcccgtcc ttgaccagga
     7261 agcctgccgc accggcctcc atggcccgcc ggagatagcc gggccggccg aacgtggtca
     7321 ggatcagcac ccggcagtcg ggcgcctggt cgcgcaggtc ggcggccgcg tccagaccgc
     7381 tgcggcccgg cagttcgatg tcgaggaggg cgacgtcggg ccggtgggtc agcgcggcgt
     7441 ccacgatcgc gtcacccgcg cccacctgag ccaccacctc gatgtccggc tccaagccga
     7501 gcagcagcgc cagggccccg cgcatcatgc cctggtcctc ggcgagcagc acccggatgg
     7561 acttgccggg ccggtggtct cggggcatct cgtcgctcac gggccaaggg taggccgcga
     7621 ggagcgcgcg ggcgcctgcc gtacggcccc gccgtgtcct cagaagtcga tcgccgtccc
     7681 gtacagccgc tccgccttca gccgcacgac cacccgccgc tcctccacct gccgggccag
     7741 ccacgcctcc tcgtcctgcg gccgggcgga ctccggcagc atggagagga gttcacggcc
     7801 cacggcgtcc cccggggcgg cggtcacgtc ggagacctcg gccgtgccct cggcgacggc
     7861 gaaggaccag acgtccggac cctgcacgtg gagcgccgcg cgcgggtcgc ggcgcaggtg
     7921 ggcgaccttg atgcggtcgg cggtggtgga gaagcgcacg aggcgggctt ccgggtccca
     7981 gctgtagacc atggtcgtca ggtgcgggtg tccgctgcgt ttggtggtgg cgagggtgcc
     8041 gaactgctgc cgggagagca ggtccgacag cgcctcgtcg gagagggcgc gggctgtggg
     8101 ttcctgagtc atggcagcgt caactccggg gcgggcgtgg gcattccggg ggcctgggga
     8161 gggaggggag ggggaggggt ggggcccccg gaggacagct cggcctctga gcggggcccc
     8221 gcctccgcac ccgccgtgtc ctgcggcagt tccgccgtca ccgtgaagcc gccgtgcggt
     8281 cccgggcccg cggtcagggt gccgcccgct gccgtgaggc gttccctcag gcccttcagg
     8341 cccgtgccgc cgaccgcgga gggcggggcg ccggccgggc cgtgtccgtc gtccgtcacc
     8401 gtcaggcgga cccggtcggc ggcgccgtgg acggcgatct cgcagtgccg ggcgccgctg
     8461 tgccgtacgg cgttggtgac cgcctcgcgg accacccagc ccagcagggc ctcggtgcgg
     8521 gcggacagcg gcgctcccga gcggcgtacc gtcggctcga caccggccgc ggtcagcacg
     8581 gagcgggccc ggtccacttc ggtggccagg ctgttctcgc ggtagccggt gaccgcctcg
     8641 cggatctcgg tgagcgcctg ccggcccacc gactcgatgt cgttgatctg ggccagggag
     8701 gcgtccaggt cgcgcggggc gaggcggcgg gccgcctccg acttcaccac gatcaccgac
     8761 agggtgtggc cgagcaggtc gtgcagatcg cgcgagaagc gcagccgctc ctcctccacc
     8821 gcgcgccggg cgagttcctc gcgggcggcg cgcagttcgc gtacggcctc ggacagggag
     8881 aggatcgcgg acgtcaccat cgtcgacagg aacgtgccgt agaggatgcc gatgccgtcc
     8941 cagccctcct tcaccccggc cacggccccg gcgaggacgg cgaggctcca gccccaccgg
     9001 ccgagccccg gtccgcgcag cacggcgccc accgcgaggc ccagcagcgg gaagaacagc
     9061 agccagttgc cgccgtaccc gatggccagg gcgcaggtca gcagggccag caggagcagt
     9121 gccacccggg tcgccggcgc gtcgcgcttg cgccggtcga aggcgcggaa ggcgaggaag
     9181 acgtagaggg agttgaaggt gaggaggccc agaccgccga tcaaggggtt cggggtctcg
     9241 ccctggaaga ggttggacag cgagcccatc cccatcagca gccagggcag cagggtgaag
     9301 ccggtgggcg gcgggcccgc atgccgttcc cgttcaccgt gcgcccggca cgtcttcctc
     9361 gaccgcagcc ctcgcatacc ctcgcccccg ttcggatgga cctgtcggaa ccgtcggcca
     9421 cgagcatcgc accgcccgcg cgccgggcgg cagacacggg cgtacggact ccggcaggac
     9481 aaatgtcacg gccggccttc gagactccag gagccagatg cccatcgacg cagcccaggc
     9541 cctcgccgcc gggccccgga ccagccgcat ctcctggacc gccaaggacg tccagctcta
     9601 ccacctcggc atccgcgccg gcgccgaccc ggacgacctg cgctacaccc tggaggaccg
     9661 gctccacgtc ctgcccgcct tcgccaccgt cgcgggcggc ggggcgccgg gcgtgatccg
     9721 cgcgctgtcg atgccgggcg tggacgtcga cctcgcgcgg gcgctgcacg ccggccagtc
     9781 gctcaccgtc caccggccgt tgccggtacg ggccaccgcg acggccacct cacgggtcac
     9841 cggcgtgtac gacaagggca cggcggccgt gctcgtgctg cgtaccgagg tcgccgacgc
     9901 cgacgggccg ctgtggacgg aggaggcacg gacctatgtg cggggcgagg gcggctgggg
     9961 cggcgagcgc gggccgtccg tgcgggcgga cgtccccgcc gggccaccgg agcagacggt
    10021 gcggcgcgcg gtgcgcgcgg accaggccct gctctaccgg ctctccggcg acctcaaccc
    10081 cctgcacgcc gacccggagt tcgcggcgcg cgccgggttc gagcggcccg tgctgcacgg
    10141 gctgtgcacg tacggcatga cgctgaaggc ggtcgtggac acgctgctcg gcggggacgt
    10201 ggcccgggtg cggtcgtacg aggcgcggtt cacgggggtg gtgtatccgg gggagaccct
    10261 gcgcatccgc ctctggcgag agggcggcac cggcgtcgtc ccggccgtgc gggtcgccgt
    10321 gggggtggtg gagcgggggg acgcgctcgt cctggacggc acggttctcc cgcacggctg
    10381 accggcgaag ggtgacggcg gcgtgctccc gcagggctga cggcaaggtt ctcccgcagg
    10441 gctgacatgc gggacagcga ggggccccga ccgtcgggcg acgatcgggg cccctgtgtt
    10501 cgctgctctg acccgccgtc aggccgcggt ggtctcggcc tgctccgccg gcttgcggtg
    10561 tcggccgcgc ggggccgtct cggtctcctg cgtggagacc ggaccccggt gcctgccgtg
    10621 ccctgcggac ccctggacct ccatgtcctg cggctgggtc gtggtggcgt tgctcatcgg
    10681 aagaactcac cccgtcaaca tgatcattcc tacagccggg cgagtttaac cggcgcacct
    10741 cggcccgaat ccagccgcac acgccaaccg gcactacttc gttacaagtc gtcccaacgg
    10801 ggcctcgcac agcggcaccg gacgcggcgt caccggctcg gacggaccct cggactccgc
    10861 ctccggggag aggggatcga cctgcgcgcg cggatccgcc ggtacggccg ggtccaccgg
    10921 cagagccggg gattcccccg ggaccggcac cgcttccggc accggcaccg gtaccaccgc
    10981 cggcgcctcc acccgggcca gcccgcacgg ctcctccccg gtcgcgtacg gcagcagcag
    11041 caccccctcc gcggtccagc gccccgcgcc cggcagccag ccgggcgggg ccacgaaggc
    11101 gtgcacctgc cgttcggccg gccgccacac gcccacccag cggccgaacg gcccgtcgac
    11161 gcgcagcgcc accccgcagc cctccggcgt cagcacctgc ccgggctgga tcgcgaacgg
    11221 cgtcaccgtg cacccgggca tgcgcaggca ctccgcgaac cgcaccggca gcgtgctgcc
    11281 cagcaccccc cagccgagcc gcggcgcacc gggggagggg gcgtcggagg cgacgatcag
    11341 caggccgctg tcggggtcgg cgagcagcag tcggtcgtcg ctgtcctcgg cgatctgcag
    11401 cagcggcgac acctcgccgc cgcgctccag gtccaccacg accgtcttgg tccggccgcc
    11461 cgtctcccgg tccagcgcca gcatccggcc ggtgtggtcc agccacacgc cgcccgagca
    11521 gcgcccgggc agctcggcga cccgctcggg cccgaaggcg ccgcccgcca ccagccacac
    11581 cgtgctggag cgccggccca cggcgagggc gtaggcgcgt tcgccgcccg gcgccggggg
    11641 cagcagccgc agcagggtgc cgtcgtcggg gcgttcgacc gcgccgagcg gcagctcgcc
    11701 ggtgcccggg ccggtcgggt agaggaggga gaaggcgtgc cggccggcgg ccagccggtg
    11761 gatcagcacc cggccgtcgc ccatcggctg cacctcggtg ccgggttcct cgggctggtt
    11821 gccgggcagc ggcacggcgt agggttcggg gccgtcgagc gtccagcgct cggggaagag
    11881 ggcgtcgccc tcgccggcga ggcgggccgc gtaggcgccg tccacggtga tcaccagccc
    11941 cgggggtgga gggaagctct cctcttgtgc cgcggcgggt tcgatcgcac aggccgtcat
    12001 cgttcggtca cctccggcga cgaagctagt tttcgcacgc acaggcgtgg catcgctggg
    12061 cgccgccttc acacataagg gtggtgcaga agcgattcac ctgaggaaac cggggcgaat
    12121 gtgctgaccg gtacatcccc ccgcacaggc ccgcacaccg gtggtcacgg ctgtacagag
    12181 gggcagatca gccaggtagc cttgcacccg tgccccgtct gtctgaagtc atcgccgcgc
    12241 tggagaacct gtggcccgcc gagcgggccg agtcctggga cgcggtcggc accgtcgcgg
    12301 gcgaccccga ccaggaggtc acgcgggtcc tgttcgccgt cgatcccgtg caggagatcg
    12361 tcgacgaggc ggtgaagctg ggcgccgacc tgctcgtcac ccaccacccg ctctatctgc
    12421 gcggtacgac gaccgtggcg gcctccacct tcaagggccg ggtcgtgcac accctgatca
    12481 agcacgacat cgcgctgcac gtcgcccaca ccaacgccga caccgccgac cccggcgtct
    12541 ccgacgccct ggccggcgcc ctcgacctgc gcgtcgtacg gcccctggtg ccggacccgg
    12601 gcgacccgga gggccgccgc ggcctcggcc ggatctgcga actggaccac ccgctgccgc
    12661 tgcgcgagtt cgccgcccgc gccgccgccc ggctgcccgc caccgcgcag ggcatccgcg
    12721 tcgccggcga cccggaggcg acgatccgca cggtcgcggt gagcggcggt tccggcgaca
    12781 gcctcttcga ccaggtccgc gaggccggcg tcgacgcctt cctcaccgcg gacctgcgcc
    12841 accacccggc ctccgaggcc cgcgcccaca gtcccctcgc gctgctcgac gcggcgcact
    12901 gggccaccga gtggccctgg tgcgagctgg ccgcgagcca gctcgacgag atctccgacc
    12961 gccacggctg ggacctgcgc gtccacgtct cgaagacggt caccgacccc tggaccagtc
    13021 actccccttc acctggagcc cccaactgaa cgccgcgccc gccgaccaga tccgactcct
    13081 cgacgtccag gccctcgacg tccgcctgca gcagctcgcc cacaagcgga agtccctgcc
    13141 cgagcacgcc gagatcgagt cgctgaccaa ggacctgacc cagctgcgcg acctgctcgt
    13201 ggccgcgcag accgaggaga gcgacaccgc ccgcgagcag accaaggccg agcaggacgt
    13261 ggaccaggtg cgccagcgcg ccgcccgcga ccagcagcgc ctggactccg gcgcggtcac
    13321 ctcccccaag gacctgtcca acctgcagca cgagatcgcc tccctcgcca agcggcaggc
    13381 cgatctggag gacgtcgtcc tggaggtcat ggagcgccgc gagtccgcgc aggcgcgggt
    13441 ggccgagctg accgagcgcg tcgcctccgt ccaggcgaag atcgacgacg cgaccggccg
    13501 ccgggacgcc gcgttcgagg agatcgacgg cgaggccgcc tccgtcacca aggagcgcga
    13561 ggtcgtcgcc gcctccgtcc ccgcggacct gctgaagctg tacgacaagc tgcgcgagca
    13621 gcagggcggc atcggcgcgg ccaagctgta cgcgcgcacc tgccagggct gccggcagga
    13681 gctggccatc accgagctga acgagatccg caaggccgcg ccggacacgg tggtgcgttg
    13741 cgagaactgc cgccgcatcc tggtccgtac ggccgagtcg ggcctgtagg gagccggtgg
    13801 cgtgcgggag ttcatcgtcg aggccgacgg cgggtcgcgg ggcaacccgg ggcccgcggg
    13861 ctacgggtcc gtggtgaagg acgcggcgac cggccagacc ctcgccgagc gggccgagta
    13921 catcggtgtc gccacgaaca acgtcgccga gtaccgcggc ctgctcgccg gcctgcgcgc
    13981 cgcgcacgag ctggacccgg cggccccggt gcacgtgcga atggactcca agctcgtcat
    14041 cgagcagatg tcgggccgct ggaagatcaa gcaccccgac atgaagccgc tcgcggcgga
    14101 ggcggcccgg gtctacccgc cggggcaggt cacctacgag tggatcccgc gcgagcagaa
    14161 caagcacgcc gaccgcctcg ccaacgaggc gatggacgcc ggcaagcgcg gcgagcagtg
    14221 ggacccgtcg gcgtcccgcg ccgagctgga cgccgtacgg gcggcggcac cggcagcacc
    14281 ggcagcaccg gccgtaccgg agccgtcggg tccgcccggc gacgccaccg cgggcgcggc
    14341 ccgggcgcgg gcggcgctgg cggagggccg ggcgccgaag gcgcaggagg agaaggctca
    14401 ggagcggcag caggcggacg cgggcgacaa ggccgaggcc gacgtacgcg cagcccgcac
    14461 cacggccgcc accacgggga cgaccgccac cacggggacg accgccccca cgggaacggc
    14521 cgccagcacg gggacgaccg cccccacggg gacgaccgcc accccctccg tctccgcccc
    14581 cggctggagc tcggcccccg acctcggcgc ccccgccacc ttcgtgctgc tccggcacgg
    14641 cgagaccccg ctgacccccc agaagcgttt ctccggtagc ggcggcaccg atccctccct
    14701 ctccgacatc ggccgggagc aggccgagcg ggtcgccgcg gcgctcgccc ggcgcggcac
    14761 gatccagcac atcgtcacct cgcccctcgc ccgcacccgc gagaccgccg ggatcgtcgc
    14821 cgcccgcctc ggcctggagg tcacggtcga ggacgggctg cgcgagacgg acttcggcgc
    14881 ctgggagggc ctgaccttcg gcgaggtccg cgagcgccat ccggacgacc tgaacgcctg
    14941 gctcgcctcc ccggaggccg cgcccaccgg tggcggggag agcttcgcgg agacggcgac
    15001 gcggatcgcc gccgcacgcg acaagctggt cgcggcgtac gccggccgca cggtcctgct
    15061 ggtcacccac gtcaccccga tcaagaccct ggtgcggctc gccctgggcg cgccgccgga
    15121 gtcgctgttc cggatggagc tgtcggcggc gtcgctgtcg gtggtggcgt actacgccga
    15181 cggcaacgcc agcctccgcc tgctcaacga cacggcacac ctgcgctgac gctcaccgca
    15241 cacccgcgct gaccgctcac cgcacacctg gaccgacgct caccgcaccc ccgccgtgag
    15301 cgtcgccgcc tcccgcgcca gccgctccac gcgcccccag tcccgtgcgg cgaccgcgtc
    15361 cgccgggagc atccaactgc cgccgacaca gccgacgttg ggcagggcga ggtagtcggg
    15421 cgcggtgtcc gggccgatgc cgcccgtcgg gcagaagcgg gcctgcggca gcggcccggc
    15481 cagcgaccgc agatacgccg taccgcccgc cgcctgcgcc gggaagaact tcatctcccg
    15541 taccccgcgc tccagcagcg ccacgacctc cgtcgccgtg gacacccccg gcaggaaggg
    15601 cactccggcc ccgcgcatcg cctccagcag tacgtccgtc cagcccgggc tgaccaggaa
    15661 ccgcgccccg gccgcgaccg actcggccac ctgccccggc gtgaggaccg tgcccgcgcc
    15721 gaccacggcg tccggtaccg cgccggcgat cgcgcggatc gactccagcg cggccggggt
    15781 ccgcagggtc acctcgatcg cgggcagccc tccggcgacg agcgcccgcg cgagcggtac
    15841 ggcgtcggcg gcgtcgtcca cgacgaccac gggcaggacg ggcgcgaggt ccagcacgga
    15901 ggcaggcaga gcagcgggca tggcctcatc ctgcccgcgc tgtgcacagt gcgcaaaggt
    15961 cattgcatat gctgcaacgc cctgcgtggg acgctcagtg gatctcctcc acgagcacgt
    16021 ccagcgccca tggcttcccc gccttcccgg gcgcctccgc ctcgacggcg tacccgagat
    16081 cccgcagcgc cgtcaccagc tcggccggcc cctgcggcgc ggccccggcg gtcagcaggc
    16141 tgcgcacgat ccgccccttg gtcgccttgt tgaagtggct gacgaccttc cgggtcggcg
    16201 cgtgcagcac ccgtacggtc gccgtccgcc ccgccacctc gcccttcggc ttccacgccg
    16261 ccgcgtacgc cgacgagcgc aggtcgagga ccagcccctc cccggccgcc tcgggcagca
    16321 cctcggccat cggtgcccgc cagtgcgcgg ccagcgcgcc gagcccgggc agcttcacgc
    16381 ccatggagca gcggtaggag gggatgcggt ccgtcacccg gacggcaccc cacagccccg
    16441 agaagacaag cagccacgca ccggcccgcc gccgcgcctc ctcgtccagg gcggcgaggc
    16501 cgagggcgtc gtacagcacc ccggtgtaga tctcgccggc gggccgggcc ccggcctcgc
    16561 gcagcccggc gttcttgccg acctccccgc gcagcccctc gctgagcccc agcacctccc
    16621 gggccttctc ctcgtccccg gcgcacagct cgaccagctc ctccagcacg gccgcgcggg
    16681 cggctgtgag ccccggcagc gacagggact ccagcgtcag cggggcgccg gtaccggacg
    16741 gggccttgcc ctcggaaggc ggcagaagga cgagcacggg acttctcctt ggtgaacggg
    16801 gaccgggaca gcgtacggcg tgccgccccg cgtcccccgc cctacggtgg cggtatgccc
    16861 cgacgccccc tccatgtgac cggcgccccc gagggcccgc tgctgacggc gctcgccgcc
    16921 ctgcgggaca agctgcacgt ccccgccggc ttcccgcccg acgtgctcgc cgcggccgac
    16981 gaggccgccg cgcaccccgt cctccccgcg gaggacgcca ccgacatccc gttcttcacc
    17041 atcgacccgc ccggctcgct cgacctcgac caggcgatgc acctgtcccg gcagggcacc
    17101 ggctaccgcg tccggtacgc catcgccgac gtcgccgcct tcgtcgtacc cgacggcccg
    17161 ctcgaccggg aggcccacca ccgggcggtc accctctact ttcccgacct gcggatcccc
    17221 ctgcacccgc cggtgctcag cgagggcgcc gcgagcctgc tgccggggca gacccggccg
    17281 gccgcggtgt ggacgatcga cctggacgcg agcggcggca cgctcgccgt cgacgtgcgc
    17341 cgcgccctga tccgcagcaa gcagcggctc gactacgaca gcgtgcagaa gaagatcgac
    17401 gacgggacgg ccgaggaacc cctgctcctg ctgaagacga tcggcctgct gcgcgagcag
    17461 gtggagatcg cccgcggcgg catctccctg cgcgtccccg accaggagat cgtcgaacac
    17521 gaccacacct acgagctgac ctaccgcgcc ccgctcgccg ccgacggctg gaacgcccag
    17581 ctctccctgc tcaccggcat ggccgccgcc gagctgatgc tggcgcacgg cacgggcgtg
    17641 ctgcgcaccc aggtgcccaa gcccggcaag ctggaggagc tgcaccacac cgccgacgcg
    17701 ctgcacatcg actggccgcc gcacatgtcg tacgcggaac gggtgcgcac cctcgacccg
    17761 tccgtgcccc gcgaggcggc gttcctccag gcctgcacgg gcctgatgag acgcgccgac
    17821 tacaccgtct tccgggacgg ccacctgccg ccgaaccccg tgcacgcctc cgtcgccgcg
    17881 ccctacgcgc actgcacggc cccgctgcgc cgcctggtcg accgctacgc caccgagatc
    17941 tgcctcgccg ccgtcgccgg ccgggagcca cccgagtggg tgctcgcggc tctcgacgcc
    18001 gtaccggccc gcatgaagga gggcggcgag cgcgcgggcg acatcgacgg caagtgcgtc
    18061 gacctggtcg aggcggccgt cctgaaggac cgggtgggcg agatcttcga gggcgtggtc
    18121 gtcaaacagg gcaacccccc gggcacgggc accgtccaac tggagtcccc cgcggtcgtc
    18181 ggccccgtca ccggcatcac cgagacggac gtcggccgcc gcctccaggt ccgcctgacc
    18241 cgcgccgaca tggaagtccc gacggtgagc ttcgcgcttg cgtgaacgct tcagtgccct
    18301 cgtgtgccgt cgtgtgccac gatcgaggga acggttcccg atctctcgga caggtgatca
    18361 gcccatgtcc cagtctggcg agcgaccgaa ggaggggcgt gacatgactg ccatggccca
    18421 cgagccgctc acgcaggagg aggtcctgct ggagggcttc ctcgccctgg acacgccgga
    18481 gggtttccgg gcggagctga tcgaggggga gatcgttgtg acaccgccgc cggacgggga
    18541 gcacgagaag tacatcagcc gcatcgtgcg gcaggtgatc aagctgtccc ggacggacat
    18601 ggacttctcc ggcaacaagg gactgaggct gaggagcgga gggggctgcc cgaagagtca
    18661 cgtgatcccg gacgtcacgt tcgcgccctt cgacctcgac ctcttcgggg gcgcggagtc
    18721 ctggatgccg tgcgacggcg tcgccatggt gctggaagtg acgtcggcca ggccgcaggc
    18781 cgaccgtgag gccaagcgcc gttgctacgc acgaggcgga atccctctgt acctgctggc
    18841 cgaccgcgac acgtcccagg tcaccctctt cagcgacccg gacaaggacg actaccgagc
    18901 gctcaccaca cgccccttcg ggaagccgat caccctcccc gagcccttcg ccttcgacct
    18961 ggacaccgcc gacctcctct gagacgcgcg ggagtcagcg cgctggagcg ggcgctcgcg
    19021 ggcatggaac ggcacgggta ggcgttgcac cctccaggac gacagggggt gtacggcatg
    19081 gcggaccagg gacgcgaaga ggcgctgtgg acgcgggcgc ggctggggcg ttgcgggccc
    19141 gcgctcgacc tgctgaccgc ccgcttcgac cagcacgtct acgcgccgca cgcgcacgac
    19201 gagtacacgg tcggcgtctg cgtcggcggc tcggaggtga tcgcgtaccg cggcggccgg
    19261 gtccacgcgg gccccggctc gatcgtcgtc ctggcccccg gcgagatcca cacgggcggc
    19321 ccggcgacga cgacggacgg ctacgcgtac cgcgcgctgt acgccgcacc ggacctcctc
    19381 gcggacggcg tgctgggcgg cggtggcctg ccgcacttcc gtgaggcgct gatcgacgac
    19441 ccggaactgg ccacggcgct gcgccgggcc cactcggaga ccgccgcctg ccccgacccc
    19501 ctggaggcgg agtcccggct gccctggctg ctgacggccc tggcccgccg ccactccacg
    19561 gcacgcgcca cgagcgacgc ggtcgccggc gcggacggca tagccaggca ggtcagggac
    19621 cgtctggccg acgagctgac cgacccgccg tcgctgtccg ccctggccac cgaactcggc
    19681 ctgtcccgct accagctcct gcgtgccttc cgtacgtccg tgggcgtccc gccgtacgcc
    19741 tggctggcgc agcaccgggt cacgcgggcc cgggccctgc tggagtcggg actgcgcccg
    19801 gcggaggtcg cgggcctggt gggcttcgcc gaccaggcgc atctgacgcg gtggttccgc
    19861 cgggtgctgg gagtgacccc ggcggcgtac cgcaacagcg ttcaagacgc gcgatgaaca
    19921 ggtggccgaa actcggccca tgactgcacg cggctggttc ctcttctccc tcatgggagt
    19981 gatctggggc atcccctatc tgatgatcaa ggtggcggtg gacgagctgt ccccgtcgat
    20041 ggtggtgttc gtccgctgcg cggtgggcgc ggcgctcctc ctccccttcg cgctccgcca
    20101 gcccggcctg gcacggaccg tggtgagcca ctggcgtccg atgctggcct tcgcgtgtat
    20161 cgagatcatc ggcccgtggt tcacgctgac ggacgccgaa cgccacctgt ccagctcgac
    20221 ggcgggcctg ctgatcgccg gcgtgccgat cgtcggcgtg gccctggccc gctacttcgg
    20281 cgcgacggaa cgcctgggga tacggcggct gacgggcctg gccctgggcc tgaccggcgt
    20341 cgtggtcctg accctcccgc acctgaccgg cggcgacgcc cgctccctcg ccgaggtcct
    20401 gctcacggtg atcggctacg cgacggcccc cctgatcgcc gcgcgccacc tgaaggacgt
    20461 gccgtccctg cacctcacgg ccccctgcct ggccctggcg gccctggtgt acgcccctgc
    20521 cgcggcggcg acctggccgt cgcagacccc gtcggcgtcg gtcctggcgt ccctggccgg
    20581 cctgggcgtg atctgcacgg cggtggcctt cgtcgccttc ctggaactga tcaaggaggc
    20641 gggcccgacg cgggcgacgg tgatcacgta cgtcaacccg gcggtggcgg tcgcggccgg
    20701 cgcgcttttc ctgaacgagg ccctgaccgc gacgatcatc gcggcgttcg ccctgatcct
    20761 gacgggttcg gtgctggcga cggccgccgc cccgaccggg gtgtcccgcc gggtacgatg
    20821 gtccacacgg cagacgagcc gggcggacgg ccgcgtggag tccccttgac ggggggcttc
    20881 ccgaggaacg tccgggctcc acagggcagg gtggtggcta acggccaccc ggggtgaccc
    20941 gcgggacagt gccacagaaa gcagaccgcc cggcgcttcg gcgcagggta agggtgaaac
    21001 ggtggtgtaa gagaccacca gtgcccaggg tgacctgggc agctaggtaa accccacccg
    21061 gagcaaggtc aaaaggagcg cctggaagga cacgaggcgc tctgcgcgga cgttcgaggg
    21121 ctgcccgccc gagtccgcgg gtagaccgca cgaggccggc ggcaacgccg gccctagatg
    21181 gatggccgtc gcccggcgct ccgcgaggag caccgggaac agaacccggc gtacagcccg
    21241 actcgtctgc cgcttccccc ttctctgccg cctctcccgt ctccgcggcc cctccgccca
    21301 gcctcttccc gccaccaatg caaacagaac tgtctgttga taagacaagc ggtgtgcggt
    21361 gagagcggcg gcttcgcagg tcactcggcg gggacctgtg gtttcttctc agccgttgtt
    21421 cgcgcggttg cctgctgatc tcttcaaaac aggcatggtt gtatggttta tttaagtgcg
    21481 gtgtcagtag gcacccgctc gctctccaag ccgtcgtacc gcagtgatca aggggcaagc
    21541 gcgatgcaga agcggtcgca gtcgacccgt caggaactcg tgtatgccgc cgtgcaactc
    21601 atcgcgaacg gccgcttcgc cgacgcgggc ctggtcaaca tctgcaacac cgccggagtg
    21661 agccggggcg cgctctacca ccacttcacg tcgatcgcgg agctgctggc cgaggtctac
    21721 gcacaggccg agaagcgcgt cctggcgctg gccgacgaca gcttcgcgtc gcggggcgcc
    21781 ggggcgccgg cgcgtttcgg catcgccctg gggaaggcgc tggcggagga tcagctggtg
    21841 cgcgccgggg tgcggttggc ggccgacggt accgacagcc ctccccggtt gagggaggag
    21901 ctgctggcgc ggctgcgcga ggaggtcctc ggggacgccc ccgtcacccc cgagcgggaa
    21961 gtgctggcgg acctggcggt ggtggtcacc gcgggactga tctcgctcgg ctacacggac
    22021 acgacgtggt ggcgcccgga gagcacgcag cggatctggg acgcgctgct gccgctcttc
    22081 acggacgccg aacggcgctg aatcggcggg ttgttgccga tgtggcagct ggggggcggc
    22141 tcagggccgg gggagtgacg gctgaccgct cacgcgccga cagccgcggg ttccggcgcg
    22201 gccgccggcg cgggcggtgg cgtgacgcgc aggtggccga tcatgccggg gctgacgatg
    22261 ccgggcagca acagccgcca catggtggtg acgcgctcgg gaaggtcctt gcggttcgtg
    22321 tagacctgcg acatcacctg catgccggtg aaggagccga cgatcatcgt ggtggcctcc
    22381 gtcaggtcca ggcccggcag ggtctcaccc tgctccctcg cctgctccag cagcccgcgg
    22441 atggtggcac tggactgctc gtacggcgtg ttgaccggcc gggtgaacga cgtgtcctcc
    22501 acggccaggc gcacactggc gcgcaggacc ggatcgcgct ggagccggta ggcgaagccg
    22561 aaggtcaggt cgatgatcgc ctgcatcttg gtgctgtcgt cgggtgcgac gagggcctcg
    22621 ctgtgcgcct ccagcagagc cgcggcgatg gcttccttgg acgggaagtg gtggtagagg
    22681 gcaccgcggg tcagaccgct ccgtgccagg atctcgttcg tgctcgcggc gtcgtaaccc
    22741 cgctcgtcga acacctcggc cgcggccctg agaatcgccc gccgtgaccg cgtcccgcgc
    22801 tcctgcttcg ccattcgtga tccctcgcac tcgccgaaga aaaaagtata ccgacttgtc
    22861 tgcatcctcg tgcagacagt ttcggagtct ctcggcgcgc gctggagatc cggtggaatc
    22921 gcccgcgggc gggccgggcc ggcgggacgg cggccttcgc acagggtggg gccgcggtcc
    22981 gccgcccgcg tcggccggtg cgccccgctt gaggtgccgg ggccgggtta cgggttgccc
    23041 aggcggaacc cgacaccccg gaccgttacg atccagtcgc tggacccgag ctttccgcgc
    23101 aggctgctga cgtgggtgtc gatggtgcgg cccttgtgcg accaggcgtc gtcccagacc
    23161 tggctcatca gctgccgccg ggagaccacg gcccccggct ggagcgcgag gatgcgcagc
    23221 aggtcgaact ccttgcgggt gaggtcgacg ggacggtcgt gcagggtcac cttgcgggcg
    23281 acggggtcga tgcgcagcgg gccgtgctcg atgacgcggg acgtccggct ggggcggacc
    23341 cggcgcatca ccgctccgat gcgggcgagc agctcgtgga agccgtacgg cttgaccatg
    23401 tagtcgtccg cgccggcctg gagacccagc acccggtcca gttcgctgcc gcgctcggtg
    23461 acggcgatga tcggggtgtc gctcaccgcc cggatgcccc ggcagacctc caggccgtcg
    23521 aggtcggtca ggtccaggtc cagcaggatg agatcgacct ggtggtggac ctggagcgcc
    23581 tgggtcccgg tggccacgct ctccgcgcga tacccccttc gggtgaggtt ctggaccagg
    23641 gtcttggccg cgcgttcctc ctcctccacg acgaggacgc gcagcgccgc gtgctcgacc
    23701 ggcgcgtgca gccgaggcgg ggtggggtgg ccggggtggt gggcggagtg ctcccacctg
    23761 gtgcgagctc ctggtgcgtc tgctacctgc cggttcatct gctccccctg tactcgggct
    23821 ggcgacggcc ctgtcagatg tttgtgatgg aaaaccaggt gcttggcgaa gataccaaac
    23881 agacttgtct gattgtcaat gtagggcccg ctgggtgggg gcggggctga cacgcgcgtg
    23941 tgagctgcgt ggatctgtga tatgccgctt ttgcgtgtcg gatcgagagg gtcgctcact
    24001 ttgccagatg cgccacactg ttcggtgtaa gcaggcaagg ttgcccgatc atgtatttcg
    24061 ttgcgtgatg catcgattac ggaacgatca cttccatctg cggtcgccga gccgaatccg
    24121 tccgccgggt gacgggcttc gagtttttac ttgatttacc cgacagacct gtctgtatct
    24181 tatggcttgg tcaacggggg gctgctgcat ggcgcagcag tttgccctcc ctgcacacac
    24241 acagaaggga gcgcacatca tgaccgcaat gctcgacacc gccctcacca cgatcgttcc
    24301 gcgccagtac gtccaccgtg ccgcggtctc cgaagtcctg ctcaccggct ggcaggcggc
    24361 cgagcaggcc gacgccttcg tggtgcgggc gcagtggccg cgcgggcacg ccctcttcgc
    24421 ccagtcgggc ggctaccagg acccgctgct gctcgtcgaa tcggtccggc agatagggtc
    24481 cctgctctcg cacgccgagt acgaggtgcc gttcgggcac cagttcctca tgctcggcat
    24541 aggcttcagc gccacccgcg acatgttcgt cgcgacgccc gccccgaccg aggtggaact
    24601 gcacaccgtg tgccgggaca tcgtccgccg gggcaaggcg ctcgccggca tgcgctacga
    24661 ggtcaccgcc atggtcgacg gagtggccct ggccaccgcc tcggcggcct tcaagtgcac
    24721 ggctcccggc gtctaccagc gcctgcgcgg ggaccgcccc acccgcgcga accgcctccc
    24781 cggcctgccg gtcgacccgg cgctggtcgg ccgtaccggc accgaacacg tggtcctgtc
    24841 gcaggacggc gcctccggca accgctggga ggtgcgcgcc gacaccgacc accccatctt
    24901 cttcgaccac cctgtcgacc acatccccgg catggtgctc ctggaggcgg cgcgacaggc
    24961 cgcccacgcc gcgaccggcc tcaccgacgc cctcgtcctc gacctggaca gctccttcgc
    25021 ccggtacgcc gaactcgacg agccctgcta catcgaggcg gacccgctcg gcgccgacga
    25081 cggcggcgac gtacaggtac gggtgcacgg ggtccagggc cggcagaccg tcttcaccgc
    25141 acgcctcgtg ctgcggcccc gcgcctgatg ggccggcacc cgggcctcgg cgcgccccac
    25201 gtcctggtca ccggcgcggc cggcttcatc ggcgcccgcg tcgcccgtgc ggcggcccgt
    25261 cacgccgggc ggctcaccct gacctcgtac cgcaggccgc cggagccggt ctccggcgcg
    25321 gtcaggaccg tccgtgccga tctggcggac ccggcgtcgc tgcgcggact gtgcgacggc
    25381 gtcgacgtcc tgctgcactg cgcctcgcag atcggcggca tgcccgaggc caacgaggcc
    25441 gtcaacgccc gcggcaccgc ggcgctcgtc gccgaggcgc ggcgcgcggg cgtggaccgc
    25501 atcgtgtacg tcagcaccgc ctccgtgtac gggcgcggca ccttccgccg cgcccacccc
    25561 ggacagctcg cacgccgccc gcagtcgccg acctcgcgga cgcgggccgc cgccgaggac
    25621 gccgtcctcg ccgccggcgg gatcgtcgta cgcccgcacg tgctgtacgg ccccggcgac
    25681 gagtgggtga tccccgggct cggccggctg ctgcgggacc tcggcggcac gccgacgggg
    25741 tggacgtcac ggcactcggt catcgccgtg accgaactgg ccgccctgct ggtcggcgtg
    25801 ggcctcgcgc cgcgcgagcg cctgtcggcg agcgtctacc acgcggcgta cccggccccg
    25861 gccccggcgt ccgccctgct ggaggccgcg gccggctgcc tggcggcgcc gccgccccgg
    25921 cgggagctgg acgtcgcgga ggcccgggag ctactggcgg gcgacgccgc cgccctgcac
    25981 acgctggacc tgctggccac cgaccactgg ttcgacagtg agcccctctg ggcggacctg
    26041 ggccggctcc ccggcccggg ctgggacgcg gacttcccgc gcatgaagga gtggtacccg
    26101 gcgccggccg cggcctgagc cgggtaccgg ggaccggcgg cccgaaccgc cgaccatgtc
    26161 cggcagttgg acagacagca ccatccgaag gatcggaatc catggaatac accaagctcg
    26221 gccgcagcgg actgaccgtg tcccggctcg tcctgggcac gatgaacttc gggacgcaga
    26281 cacccgagga ggacagtcac gcgatcatga gccgcgcgca cgagcacggc atcaacttct
    26341 tcgacacggc caacgtgtac ggcacgcggc cgggggaggt gtccaccgag gagatcatgg
    26401 ggcggtggtt cgcctccggc ggcggccggc gggagaggac cgtcctcgcc accaaggtct
    26461 acatccccac gggcagctgg cccaacgagg gcttcctgtc cgcgctgaac atccggcgcg
    26521 cctgcgaggc gtcgctgcgg cgcctgcaga ccgactacat cgacgtgtac cagatgcacc
    26581 acgtcgaccg ggacacgccg tgggaggaga tctgggaggc gttcagcgtc ctgcgccagc
    26641 agggcaaggt gctgtacttc ggttcctcca acttcgccgg ctggcacctc gcccaggcgc
    26701 aggaggccgc ccgcgcccgg cacttcctcg ggctggtgag cgagcagtcc atgtacaacc
    26761 tgatgacgcg ctgggtcgaa ctggaggtcc tgcccgccgc acggcactac ggcgtcggcg
    26821 tcatcccgtg ggggccgctg cacggcggcg tcctcggcgg cgtcctgcgc aagcagaagg
    26881 agggcaggac cgcccggggc agcaccggcc gctcggtcgg cgtgctcgcc cggcaccgcg
    26941 acaccatcga ggcgtacgag aagctgtgcg ccgacatcgg tgcggacccc gcccacgtcg
    27001 gactggcctg gctgctcgcc caggagggtg tcaccgggcc catcatcggc ccgcggacca
    27061 ccgagcagct cgacagctcg ctgaccgcgc tgacgatccg gctcgacgac gccacgctgg
    27121 cgaagctgga cgaactgttc ccgccgcccg gcccgaacgg ggcacggccc gctcccgagg
    27181 cctacgcctg gtgagcgtgc gaaagcgctg aacaccgccg ggtgggggag gcgttcgacg
    27241 cccgcctcac ccggctctcc cccccgtccg caccgcgccc ccgacgtgcc cggagcgagg
    27301 ccgcggcgga cggggaggct gccgcaacca tccgttctct cccagaaaag agacatcgtg
    27361 cgcaaggtgc tcatcgccaa ccgtggcgaa atcgctgtcc gcgtggcccg ggcctgccgg
    27421 gacgccggga tcgcgagcgt gggggtgtac gcggacccgg accgggaggc ggtgcacgtc
    27481 cgtgcggtcg acgaggcgtt cggactcggc ggcgacaccc cggcctccag ttatctggtc
    27541 atcgacaaga tcctgaatgc cgcccgggag tcgggggcgg acgccgtcca tcccggttac
    27601 ggcttcctct ccgagaacgc ggagttcgcg caggcggtca tcgacgcggg tctgatctgg
    27661 atcggcccgc ccccgcaggc catccgtgac ctgggggaca aggtcgccgc ccggcacatc
    27721 gcccagcgtg ccggcgcccc cctggtggcc ggcaccccgg acccggtctc cggcgccgac
    27781 gaggtcgtcg cgttcgccaa ggagcacggc ctgcccatcg cgatcaaggc cgccttcggt
    27841 ggcggcggcc gcggtctgaa ggtcgcccgc accctggagg aagtccccga gctgtacgac
    27901 tccgccgtgc gtgaggcggt cgccgcgttc gggcgcgggg agtgcttcgt cgagcgctac
    27961 ctcgacaagc cccgccacgt ggagacgcag tgcctggcgg acaagcacgg caacgtcgtc
    28021 gtcgtctcca cccgtgactg ctcgctgcag cgccgccacc agaagctggt cgaggaggcg
    28081 ccggcgccgt ttttgaacga ggagcaggtc gcggagctgt accgggcgtc gaaggcgatc
    28141 ctgaaggagg ccggctacgt cggcgccggt acggtggagt tcctcgtcgg cctggacggc
    28201 acgatctcct tcctggaggt caacacccgc ctgcaggtcg agcacccggt caccgaggag
    28261 gtcgccggca tcgacctggt gcgggagatg ttccgcatcg ccgacggcga ggaactcggc
    28321 tacgacgacc cggtcctgcg cgggcactcc ttcgagttcc gcatcaacgg cgaggacccc
    28381 ggccgcaact tcctgcccgc ccccggcacg gtcacccgct tcgacgcccc ctcgggtccg
    28441 ggtgtgcgcc tggacgcggg tgtggagtcg ggcagcgtga tcggcccggc ctgggactcg
    28501 ctgctggcca agctgatcgt gaccggccgc acccgcaagg aggccctgca gcgcgccgcg
    28561 cgtgcgctgg aggagttcca ggtcgagggc atggccaccg ccatcccctt ccaccgcgcg
    28621 gtcgtgaagg accccgcctt cgcgccggag ctgaccggct cggccgaccc gttcacggtc
    28681 cacacccggt ggatcgagac ggagttcgtc aacgacatca agcccttcgc cgcccccgcc
    28741 gatgccgagg cggaggagga ggcgggccgc gagaccgtcg tcgtcgaggt cggcggcaag
    28801 cgtcttgagg tctccctgcc ctccagcctg ggcatgagcc tggcccgtac cggcctggcc
    28861 gccggcgcca agcccaagcg gcgcgcggcg aagaagtccg gcccggtcgc ctcgggcgac
    28921 accctgacct cgccgatgca gggcaccatc gtgaagatcg cggtggaaga gggccaggag
    28981 gtcaaggagg gcgacctgat cgtcgtcctg gaggccatga agatggaaca gcccctcaac
    29041 gcacacaagt ccggcaccat caagggcctg tccgccgagg tcggcgcctc cctcacctcc
    29101 ggcgccgcca tctgcgagat caaggactga gtccgacagt cgcagcacca agggctcccg
    29161 gcgatacgcc gggagccctc gtgcgatgtg gccggtcgtt cgcggcgggc ccggctaggc
    29221 cgcgcccgcc cggtgcttga gcgtctcgta gacgtccgcc gcgtggtagt acgtgcgtcc
    29281 cgactggctg cggcgccgcc acttccgggt gctggcgtgc cggtagacgc tgcccggcgg
    29341 catggaccac agccgcgcta tgtccgcggc ggtcacccag cgcgtctcgg gctgcggggc
    29401 cgccgcgccg gatccgggcc ggtcctcggc gtccgcaccg gtcgggggcg tcgctccggt
    29461 cgtgtcggtc gtacgggtca taccggtcgt accggtccgg tcggtcgtac cggtcgtgcc
    29521 ggtcgtgtcg gtcgtgcccg cggtggcacc cttcgccgac gcggcggccc cgcccagccg
    29581 gcggctgagc tggagcagct cgggtccgaa ccagcggtgg gaaccgtccg ccgtacacgt
    29641 gatcgtggcg ggccacttgg ggtgctgggg ccgtacgacc gcggtcaggc cgccggggca
    29701 gcccggctcc acgcactcgc ctatgggtat gcgccggcgc gtcaccgggt ccatcacgct
    29761 gtgcgcccgg cgcaccaacc gcgccacctc ggcggacagg tcaccggcag cgtcatgccg
    29821 cgcgagccat ccgctgtgcc ggagcaggaa cgcggcgagc gggcccaccg cccgccgcgg
    29881 accggccagt cccagctcct ccacgaccag cgtcgcccag gagccgagca cggccaggat
    29941 cgacgaacgc acctcggcgg cccaggagtt gaagggcgtg ccgggcagcg gaccgccgga
    30001 ggtgcgctcc gcacagcgct cgccgccgct gccgtcgagg tgccgtgcgc attcctcgta
    30061 cagctccggc agccgggtca ggtcccgcac caggtggtcg tggcacggcc ggcacaaccg
    30121 ggcacccggc tcggccggcc gccggtcccc gccaccgtcc gcgcgacggg cacagccgtg
    30181 tccggcacag gccgtcgtca ccgcgggcat acggatgctc ccctggttca ccgcaactcc
    30241 tcctagtggt cgcccatgaa caggggaacg ctaattccgc aattctcggg acggcaaggg
    30301 cggcagaacc tcgcctgtgc ttcgcgacgg aattcagaga aatcccggag gttcttttcc
    30361 ggcttctgac acgcccgccc cgtcatctgc cggatgacct ttttctgacg acgtttgacc
    30421 gggatctgac atgggattcc ttgaccggcc gacggcgatc gaagaagctt tgaggcagag
    30481 tccacagccg tgtgcccgaa tcgtctcgca ccgtgtgcgg cagagaccga cctaccccaa
    30541 ggacgagatg aattcccctc gcgcccggac cttccagtcc ctgacgatcc gcaacttccg
    30601 cctgttcgcg gcgggacagc tcgtctccgt ggccggtacc tggatgatgg tggtcgcgca
    30661 ggactggctc gtgctcgcac tgaccggtga ttccgggacc gcgctgggca tggtgacggc
    30721 ctttcagttc gcgcccctgc tgctgttcac cctgcacgcg ggcggcctcg ccgaccggta
    30781 cgacaagcgc cggctgctga tctgcgcgaa cctcacctcg ggcgcgctgg ccctgtgcct
    30841 gggcgtcctg gtgctggcgg gcgtcgcccg gctgtggcac gtctgtctct tcgccctcgg
    30901 gctcggcctc gtcaacgccg tcgaggtgcc cacccggatg tcgttcgtca gcgaactcgt
    30961 cggcgccgac ctcctgccca acgcgtccgc gctgagcgcc gcgtacttca acgccgcgcg
    31021 cgtggccggg cccgccgtcg ccggcctgct gatcggctgg ctgggcacgg gggccgtgat
    31081 gctgctgaac gcggtgagct atctggcgac ggtggccgcg ctgcgggcga tgcggccggg
    31141 cgaactgcac cgggacgggc ggcgccccga gcgggcaccc gtccgtgacg gcctgcggca
    31201 cacggcggcc cgtgccgacc tgctgctgcc gatggtcctg gtggccgtcg tcggcatgct
    31261 gggcttcaac ttccagctca ccctgcccct gctcgccaag acggtcttcc acgcgcgggc
    31321 cttcgacttc ggcctgctca cgacggcctt cgcggcgggc tccctgctcg ccgcgttcgt
    31381 caccacgcac cgccgcggcc ggcccccggc cggtctcgtg accggctcgg ccctcgcgtt
    31441 cggcgcgctg gagaccgcgg ccgggctcgc cccgacctac gccacggccc tggtgctgct
    31501 gctgggcacc gggttcggcg cgatctactt cgcgcaggcc gccaaccacc ggatccaact
    31561 gggcaccgac cccgcctacc gcggccgggt gatggccctc tacaccctgg tcttccaggg
    31621 caccaccccg ctgggcgcgc tgctgatcgg cgccctcagc gaacggttcg gcgcccgctc
    31681 cggcctgctg gcgggcggag tggccacgct cctcgccgcg tccgccgtgc tcgtcgccca
    31741 acggcgcgcc cgccccgcgg ccgcggtcac cggcagggcc gacgagccca gcacccggac
    31801 ctccggggaa ccggcccgct gaacacgggg cggacgaccg ggccggggtt acgaccggac
    31861 caggtgcatg accggaccgg ctgcttgacc ggaccgggtg tacgaccgag gcggtcgtac
    31921 gtcccgaccc gacgcgtcgg ccgtagaccc ccgtcggccc ccgaccgcag atgccgccgg
    31981 cccccgggcc gccgacgccg cccgcccccc ggccgtagac cggaccgccc cccggccgca
    32041 gaccccgacc ggacaccctc acccgaggac gcggccgccc tcggcccgcc ttcccgtccg
    32101 aacgccacac ggaggaacac actcatggcc atccaggaag caacgatcac ccgcaccccc
    32161 gccggctcgg ccgaggaacg gcaggacgtc gtccgggcgg cccgcgccgt cttcgcccgg
    32221 gagggctgga cgcacagcgg tgtcgcggac atcgcccggg agagcggcct cgacgaggcc
    32281 acggtcacgc actacttccc ggacaaggaa cggctgctgc tcaccgtcct gctggagggc
    32341 gccgcctcgg tcgccgccgc gctgacggtc atcgcggaga atcacctcgc cgacgtcacc
    32401 gacctggaga aggacctgat cgcgctcggc cacgcctggc tgaccccgct ggccgacttc
    32461 cccgagcact tcgccatcgt gcgccacctc ggcgccgaga tcgccgcctg gccggccggc
    32521 gtggtggaga tgtggcggac ggccggcccc cggcaggcca cccgtgaact gggccgccgc
    32581 ctggagcgcc tcgccgaccg ggggctgctc gccttcgacg acagcgacca cgccgccgag
    32641 cgcttcatcc agctggtcgc gggcggcgtc gtccagcgct ccttccacgg cgccctgccg
    32701 ctcgccgact tcgagaccga ggcgctcgtc gccgcgggtg tcgcggactt cgtgcgcctg
    32761 taccggccgg gcgccggccg ctgacccgcg gcagccagcc cggccccgaa ccacgagaga
    32821 accctcgggg aatcccacga cccacggagg aatccgaccg acccacggag gtgggagaca
    32881 ccatggccac accgcacgac tcgatccagg cccggatcga cgagctgacc gagatcaagg
    32941 aggcagcgcg gctcggcccc gacccggcgg ccaccgagcg ccagcacaac aagggcaagc
    33001 tgacggcgca cgagcggatc gccctgctgc tggacaaggg ctcgttcaac gaggtggagc
    33061 cgctgcgccg gcaccgggcc accggcttcg gactggagga caagaagccg tacagcgacg
    33121 gcgtggtgac cggctggggc accgtgcacg gccgcaccgt cttcgtctac gcccacgact
    33181 tccgcatctt cggcggcgcg ctcggcgagg cccacgccca gaagatccac aagatcatgg
    33241 acctggccga ggcggcgggc gccccgctgg tctcgctcaa cgacggcgcc ggcgcccgga
    33301 tccaggaggg cgtcaccgcg ctcgccgggt acggcggcat cttccagcgc aacacccgct
    33361 cctccggcgt catcccgcag atctccgtga tgctcggccc gtgcgcgggc ggcgccgcct
    33421 actcgcccgc gctgaccgac ttcgtcttca tggtccgcga gaccagccag atgttcatca
    33481 ccgggcccga cgtcgtcaag gccgtcaccg gcgaggagat cacccagaac gggctcggcg
    33541 gggccgacgt ccactccacc acctcgggcg tctcccactt cgcctacgac accgaggagg
    33601 agtgcctgga ggacgtccgc tacctgctgt cgctgctgcc cgccaacaac cgtgagctgg
    33661 cgcccgtcga gcggtccggc gaccccgtcg accgggtcaa cgacgcgctg ctggacctcg
    33721 tcccggccgc cgccgggcag tcgtacgaca tccgcgcggt catcgaggag gtcgtcgacg
    33781 acggcgagtt cttcgaggtg cacccgctgt gggcgacgaa catcgtgtgc gcgttcgccc
    33841 ggctcgacgg gcacgtcgtc ggcatcgtcg ccaaccagcc cgccgccatg gccggcgtgc
    33901 tggacatcga ggcctcggag aagggcgccc gcttcgtgca gttctgcgac gccttcaaca
    33961 tcccgctcgt caccctggtc gacgtccccg gcttcctgcc cggcgtggac caggagcacg
    34021 acggcatcat ccggcgcggc gccaagctgc tgtacgccta ctgcaacgcc accgtgccgc
    34081 gtatctcgct ggtgctgcgc aaggcgtacg gcggcgcgta catcgtcatg gactcccggt
    34141 ccatcggcgc cgacctggcc ctcgcctggc cgaccaacga gatcgcggtg atgggcgccg
    34201 agggcgccgc caacgtcatc ttccgccgcg agatcaacgc cgcggaggac ccggaggcgg
    34261 tgcgccgaca gcgcatcaag gagtacaaga gcgagctgat gcacccctac tacgcggccg
    34321 agcgcgggct gatcgacgac gtcatcgacc cccgcgagac ccgcgcggtg ctgatccgtt
    34381 cgctggagat gctgcgcgcc aagcacgcgg acctgccctc gcggaagcac ggtaaccccc
    34441 cgcagtgact cctctgtagt tctggacgcg gatttgacgt aaagcccccc gatcagcctt
    34501 gaaatcgggg gagttgccga agaagatgga tgtcagagtc cggagctttg tcgccgacgt
    34561 tttcggctgg acgcccgctc atcctttctt cggatccttc cgagccagaa acctttctcc
    34621 gccccacggc ctttcgcgcc cttttcggga ccggaccact tggagaagaa tcgcatgcac
    34681 agcaacctga tcgtggccag gatggagccc gcctcgggcg cccaggtggc cgaactcttc
    34741 agggcgttcg acgccacgga aatgccgcac ctgatgggca cccgccggcg tcagctcttc
    34801 cactaccgcg gtctgtactt ccacctccag gacttcgaca cggacaacgg tggacagcag
    34861 atcgaggaag ccaagaccga cccgcgcttc atacggatca gcgaagacct gaagccgttc
    34921 atcgaggcgt acgacccggc gacctggcgc tcgccggccg atgccatggc gacccgcttc
    34981 taccactggg aggcgggctc gtgaccggcc ggcgcgttgt catcacgggc ctggaggtgc
    35041 tcgcccccgg cggggtgggc accgacgcgt tctggtccct gctgagcgag ggccgtacgg
    35101 cgacccgcgg gatcaccttc ttcgacccct cgccgttccg ctcccgggtc gccgccgaga
    35161 tcgacttcga tccggaggcg cacggactga gcccgcagga gatccgccgg atggaccgcg
    35221 cgggccagtt cgccgtcgtc gcggcccgcg gcgccgtcgc cgacagcggc ctcgacctga
    35281 cggaccacga ggcacaccgg gtcggcgtca ccgtcggcac cgcggtcggc gccaccatgg
    35341 gcctcgacca ggagtaccgg gtcgtcagcg acggcggccg gctgaacctc gtcgaccacc
    35401 actacgccgt cccgcacctg cacaactacc tggtgcccag ctccttcgcc gccgaagtgg
    35461 cctgggccgt cggggcggag ggcgccaacg cggtggtgtc caccggctgc acctccggca
    35521 tcgactccgt cggctacgcc gtcgagctga tccgcgaggg gaccgcggac gtcatggtcg
    35581 cgggcgccac cgacgccccg atctcgccga tcacgatggc gtgcttcgac gcgatccggg
    35641 cgaccacccc gcgccacgac gaacccgagc gcgcctcccg gccgttcgac agcacccgca
    35701 acgggttcgt gctcggcgag ggctccgcct tcttcgtcct ggaggagctg gagagcgccc
    35761 gccggcgggg cgcccgcatc tacgcggaga tcgccggcta cgcgacccgc agcaacgcct
    35821 accacatgac cgggctccgc cccgacggcg ccgagatggc cgaggccatc cgggtctcgc
    35881 tcgacgaggc gcggctgaac ccggaggaca tcgactacgt caacgcgcac ggctcgggca
    35941 ccaagcagaa cgaccggcac gagaccgccg cgttcaagaa gagcctgggc gagcacgcct
    36001 accggacgcc ggtcagctcc atcaagtcga tggtcggcca ctccctcggt gccatcggag
    36061 ccatcgagat cgccgcctcg acgctggcca tgacgcatca cgtggtgccg cccacggcga
    36121 acctgcacgc ccccgatccc gaatgcgatc tcgactatgt gcctctcacc gcccgcgaac
    36181 accggacgga cgccgtgctg accgtcggca gcggcttcgg aggcttccag agcgccatgg
    36241 tgctggcccg cccggaaagg accgccgcat gagcacctca gtcgtggtga ccggcctggg
    36301 cgtggtcgcg cccaacggcc tcggcgccga ggagtactgg tccgcggccc gtgtcggcaa
    36361 gagcggcatc ggccggctga cccggttcga cccgacccag tacccggccc ggctcgcggg
    36421 cgagatccac gggttcgagg ccgaggagta cctgccgagc aagctgctgc cgcagaccga
    36481 ccgcatgacc cggctcgcgc tcgtcgccgc cgactgggcg ctggaggacg ccggggtgcg
    36541 cccgcaggag ctgcccgcct tcgacatggg cgtggtcacc tccagcgcct cgggcggctt
    36601 cgagttcggc cagcgcgagc tggagcggct gtggagccag ggcagcgagt acgtcagcgc
    36661 ctaccagtcc ttcgcctggt tctacgccgt caacagcggc cagatctcca tccggcacgg
    36721 catgaagggc ccgagcggcg tcgtcgtcag cgagcaggcc ggcggcctgg actgcctcgc
    36781 gcaggcccgc cgccaggtcc gcaagggcac gccgctggtc gtctccgggg ccgtcgacgc
    36841 ctcgctgtgc ccgtggggct gggtggccca gatgaccagc ggccgggtca ccacgagcga
    36901 ggacccggcc ggcgcctacg tgcccttcga cgaccgggcg tcgggccatg tgcccggcga
    36961 gggcggtgcc ctcctggtcc tggagggcaa ggaggccgcc cgtgcccgcg gcgcgaaggt
    37021 gtacggcgag atcgcggggt acggcgcgac gttcgacccg aagccgggca gcgggcgtcc
    37081 gtccacgctg cgcaaggcga tcgagaccgc gctggccgac gccggtgtcg aggcccgtga
    37141 cgtggacgtc gtcttcgccg acggcgcggc cgtcccggag ctggaccgga tcgaggcgga
    37201 ggccctgaac gaggtcttcg gcacgggtca ggtggccgtc accgtcccca agacgatgac
    37261 cggggccctg tactcggcgg cgggcgcgct cgacgtcgcc accgtcctcc tcgcgatgga
    37321 ggaaggcctg atcccgccca ccatgaacac cgagccggcc gagcggtacg gcctggacct
    37381 cgtcgccggc cacccgcgga ccaccgaggt gcgcaccgcg ctggtcgtgg cccgcggcca
    37441 ggggggcttc aactcggcgc tggtcgtccg cgcggccgac tgaccggccg ccccgccccg
    37501 gagacccgcg gcacgcgccg gccgggacac accctcacca ccgggcccgc cggcccggca
    37561 acccacccgc gcgccgaccg ggagaccgac cgcgcgccgg ccccggggcc tgccgtgcac
    37621 aggctccggg gcccgtggcg caccggacgg gagcgcccgg actccgactc ccgccgggcg
    37681 tcgaccggga gaccgaccgc gcgccggccc cggggcctgc cgtgcacagg ccccggggcc
    37741 cgtcgcgcac cggacgggag cgcccggacc ccgactcccg ccgcgcgccg accgggagac
    37801 cggccgcgcg tccgccccga ggcctgccgt gcacaggctc cggggcccgt ggcgcgccgg
    37861 acgggagcgc ccggaccgca actcccgccg ggcgtcggcc ccggggcctg ccgtgcacag
    37921 gccccggggc ccgtcgcgca ccgcaccggt gcgcccgtac cgcaactccc gccgcgcgcc
    37981 ggccccgagc cccgcgcgtc ggaccacacc cccccacagc gcgccggccc ggacccccca
    38041 ccgcggccgg gccggcaccc accggaagcc gaagccgctt cgggttccgg cgccaggccg
    38101 tgccggaagc cgaagccgaa ccgaaaagga acaaccgtca tggccgagca ggtattcacc
    38161 ctcgacgacc tccgccgcat cctcatcgag gcggcgggcg acgacgagtc ctacaacctg
    38221 gacggagaca tcctcgacac cgagttcgag gagctgggct acgagtcgct ggccctgctg
    38281 gagaccggcg gccgcataga gcgcgagtac ggcatctcgc tcgacgagga ggtgctgagc
    38341 atcgcgaaca ccccgcgcct gctgatcgac accgtcaacg ccggtctcgc cgccctggtc
    38401 tgatccgtcc ctcccgccgg gcggtgcccc gccgccgccc ggcggacgcg ttccccaagc
    38461 ccccaaccga ccactggaga cgacagacat gtcagagcag gaaaagcggg tcgctctcgt
    38521 cacgggagcc accagcggga tcggcctcgc cagcgcccgg ctgctggccc agcagggcca
    38581 ccgggtgttc atcggcgccc gcaacgccga caacgtcgcg gcgaccgtga aggacctgca
    38641 ggccgagggc ctggaggtgg acggcgccac cgtcgacgtc cgctccggcg acgaggtccg
    38701 cgccttcgtc caggccgcgg tcgacacctt cggcaccatc gacgtgctgg tcaacaacgc
    38761 gggccgcagc ggcggcggcg tcaccgccga catcgacgac gaactgtggg cggacgtcgt
    38821 cgagaccaac ctcaccagcg tcttccgcgt gacccgcgag gtgctcaaca ccggagggat
    38881 gcggcacaag agccgcggcc ggatcatcaa catcgcctcg accgccggca agcagggcgt
    38941 ggtgctcggt gcgccgtact cggcgtccaa gcacggcgtc gtcggcttca ccaaggcgct
    39001 cggcaacgaa ctcgcgccca ccggcatcac cgtcaacgcc gtctgcccgg gctacgtcga
    39061 gacccccatg gcccagcgcg tgcgccaggg ctacgcggcc gcctacgaca cgaccgagga
    39121 cgccatcctg gagaagttcc aggcgaagat cccgctcggc cgttactcca cccccgagga
    39181 ggtggccggt ctcgtcggct acctggcgtc cgacacggcg gcctccatca cggcgcaggc
    39241 gctcaacgtc tgcggcggac tcggcaactt ctgatcccgg cctcgaggag agctgatcat
    39301 gaccatccgt gaggtcgaac acgagatcac cgcgaaggcc ccggccgaga cggtgtaccg
    39361 gctgatcgcc gaggtggaga actggccgcg gatcttcccg ccgaccatcc acgtcgagca
    39421 cgtggagcgc ggcgagcgcg acgagcgcat acggatctgg gccaccgcca acggcgagcc
    39481 gaagaactgg gcgtcgcgcc gcaccctgga cccggacacc ctgcggatcg acttccggca
    39541 ggaggtgtcc accccgccgg tggcggccat gggcggggcc tggatcatcg agccgctgtc
    39601 ggcggacgag tgccggatcc ggctgctgca cgactaccgg gcggtggacg acgaccccgc
    39661 cggactcgcc tggatcgacg aggccgtcga ccgcaactcg cgctccgagc tggccgccct
    39721 gcgcaccaac gtcgaacgcg cccacgccga ggccgacctg acgttctcct tcgaggactc
    39781 cgtcgagatc gccggatccg ccaaggacgt ctacgacttc atcaacgagg ccgacctgtg
    39841 ggccgagcgg ctgccgcacg tcgcctcggt acggctgacc gaggacaccc ccggcctgca
    39901 gaccctggag atggacaccc gcgcccgcga cggctccgtc cacaccacga agtcgtaccg
    39961 ggtgacgttc ccgcaccaca agatcgccta caagcaggtg accctcccgg cgctgatgac
    40021 gctgcacacc ggctactgga cgttcaccga gaccgacacc ggcgtcacgg cgtcctccca
    40081 gcacaccgtg accctcaaca ccgccaacat cgcccgtgtc ctcggcgagg acgccaccgt
    40141 cgccgacgcc cgcgcctatg tgcgggacgc gctgagcacc aacagcaggg ccacgctcgg
    40201 ccacgcgaag gcccatgccg aggcgcggcg ctgaaccgga cggcgccggt cggacggccg
    40261 gctccccgcg tcgtcccctg gtcccggtgc tccgcgaggc accggaactc tcgctgtggc
    40321 tgctgcgctc accgtccccg gacagtgccg cggcagcccg gctggcggtg cgcgagctgg
    40381 acgacacgga ggtgcgccgg gccgcgctgt tcgtgcggcc cgcggaccgg gtgcagtacc
    40441 tgtcggcgca catcgccctg cgccggatcc tcgcggcgac cacgggctgc ccgccggagt
    40501 cgctgcggct gggccgcgag cccggcccgc tgctctcccc ccgtaccagc aggcccgtgc
    40561 tgcggcaccc gccggtgccg gtgcacttct cgctctcgca cagtcacggg ctgatcctca
    40621 tcggcacggc cgcctcggcc gtcggcgttg acgtgcagcg cacgccgacg atcgaggcgg
    40681 tgcgggtggt gggacccgcg ctgcacccgg cggagtggcg ggaactcctc gccctccccg
    40741 aaccgcggcg accggcggcc ttcgcgcagc tgtggacccg caaggaggcc tacctcaagg
    40801 gcctgggcac cggcctggtc cgtggcccgg ccctggacta cctggggctc ggcaccgacg
    40861 ccgacgcccc gcccggcccg cccggctgga tcgtccgcga cgtcctggtc gggccgcatc
    40921 acgctgctgc cgccgccctg gccgtcgccg tggaaccgcg catcacgctg cgcacgctgc
    40981 cggtggcgtg cctgtacgac ggcgacgcgg gactgccgct gtccgcggcc ccgctacttg
    41041 ctctgagaag gagaggttca tggacgcttc ggtggtcgtt gttggagcgg gacccgccgg
    41101 gctgatgctc gccggggaac tccggctcgc cggaaccgac gtcaccgtgc tggaacgcca
    41161 tccccgccgc accggcgagt cacgggggat cggcctgacc atcggcacca tggaggtgtt
    41221 cgaccagcgc ggactcctgg gcaggctcgg cccctacgag acgagcggca tggggcactt
    41281 cggcggcgtg ccgctggaca tgagtgtcct cgggcgggcc cacgaggccg cccgcacggt
    41341 cccgcagtcg gtgaccgagg aggccctgga gtcctgggcg cgcgacctcg gcgccgacat
    41401 ccggcgcgga cacgagttcg tgtcgtacga ggacacgggc gacggactga ccgtgacggt
    41461 ccgtcacccg ggcggcgagg agcggatcca cacccgctac ctcgtcggct gcgacggcgg
    41521 gcgcagctct gtgcgcaagg cggcggggtt cgacttcccc ggcaccgccg ccaccaccga
    41581 gatgttgctg gccgacgtgc gcggagtcga cctggagccg cgcatgaccg gccagcacgt
    41641 cggcggcggg ttcgtgatgg tcgccaagct ggccggcggc atccaccggc tcatcgtcgg
    41701 cgagcacggc ataccgcccc gccggcgcac cgagccgccc gccttcgccg aggtcgccga
    41761 cctgtggaag cggctcacgg gcgaggacgt ctcgcacgcg gagcccgtct gggtcagcgc
    41821 cttcggcaac gccacccggc aggtcaccga gtaccggcgc ggccgggtcc tgctcgccgg
    41881 cgactccgcg cacgtgcacc tgcccgcggg cgggcagggc atgaacacca gcgtccagga
    41941 cgcgcacaac ctcggctgga aactcgcggc ggtgctgcgc ggggacaccc ccgaggagct
    42001 gctcgacacc taccacggcg aacgccacga ggtgggccgc gccctgctcg ccaacacccg
    42061 cgcccagagc ctgctggtgc tgggcggcga ggaggcccag ccgctgcgtg acgtgctggc
    42121 cgagctgatc gcctaccccg aggtcacccg gcacctcgcg gccaaggtca gcggcctgga
    42181 catccgctac gacgtcggcg gcggcaccca cccgctgctc ggccggcgca tgccgcacct
    42241 gccggtgacg acggcgagcg ggccgaccag cagcaccgcg ctgctgcgca ccgggcgcgg
    42301 ggtgctcctc gacctggagg acaacgccgt gctgcgccgc cgcgcgcacg cctggcgcga
    42361 ccgcgtcgac gtcgtcaccg ccacccccgg cgcgctgccc gaggacagcc cgctggccgg
    42421 caccgccgcg gtgctgctgc gccccgacgg ctacgtcgcc tgggccgcac ccggcagcca
    42481 ccgcgacctg aactccgccc tgacccgctg gttcgggccg ggcctgggac ggcgctgatg
    42541 gcacggcaga cacccgacgc ggacgtcctc gtcgtcggcg ccggacccgt ggggctgttc
    42601 ctcgcggccg agctgcgcgc cgagggcgcc cacaccgtcg tactggaacg gcttcccgag
    42661 ccgaccggag agtcgcgggc ctccgtcctg cacgccagga ccatggagat cttcgccgac
    42721 cggggcttcc tgccgaagct cggcgagctg ccgcccgtgg gcgccggcca cttcggcggg
    42781 ctgcgtctgg acctggccga cgccgccccg gaccacccgt acgccgggca gtgggagtgc
    42841 ctgcagtacc acctggaggc cgaactcgaa cgccacgccc gcgacctggg cgccgacatc
    42901 cggcgcggcc acaccctcac cgggctgtcg cagtccggcg acggcgtccg cgccgaggtg
    42961 cgccggccgg acggcacccg gtacaccctc acggccggct acctggccgg ctgcgacggc
    43021 gaacgcagca ccgtgcgcga cctcgccggc ttcgaactcg ccgggcacga ggcggacaag
    43081 gtgatgctgc gcgccgacat cgcgggcgtc gagctggaca accggcgcct gcagcggttc
    43141 cccgacggca tcgccaccgc ctaccgcagg cccgacggca ccacccggct gatggtgcac
    43201 cggttcggcg aacagcccgc cggcgaggtg accttcgagc aggtcgtcac cgcgtgggcg
    43261 gccgtgaccg gcgaggacat cggtcacgga cgggccctgt ggctcaaccg gttcgacaac
    43321 gcctcccggc aggtcaccga gtaccggcgc ggccgggtgc tgctcgccgg tgacgccgcg
    43381 caccagcaga tgccggtcgg cggacaggcc gtcaacctcg gcctgcagga cgcggccaac
    43441 ctcggctgga agctcgcccg ggtggccacc gggcaggccc ggctcgcact gctcgacacc
    43501 tatcacgccg agcggcaccc ggtcggcgcg cgcaccctcg cccacatccg ggcccaggcc
    43561 cacctgctgt tcggcaccga ggaggtcacc gcgctccgtg acgtcttcgg cgagctgctg
    43621 gagttcgccg gcgtccgccg ccacctcgcc cgcgcgatca gcggcctcga cgtcacggaa
    43681 cagccccggc ccgaccggcc ggccgagccc gcgccgcaca ccggcggccg ggcccggccc
    43741 ctccgcccgc acccctcgca cacccaccca tccggaaggt caaccgtgga caggctcacc
    43801 gacaagaccg ccctcgtgac cggttccagc cgcggcatcg gcagggcgac ggcgatccgg
    43861 ctcgcccgcg agggcgcgct ggtcgcggtg cactacacgg ccaaccaggc ggcggccgag
    43921 gagaccgtcg aactcatcga gaaggaaggc ggcagcgcct tcaccgtccg cgccgaactc
    43981 ggcgtccccg gcgacgtgca cgaactcttc ctcggcctcg aacgcggcct gaaggagcgc
    44041 accggcgaca cccgcctgga catcctggtc aacaacgcgg ccgtcacctc gacgggcgcg
    44101 gcgccggagg acctcacccc cgaggagttc gaccgctact tcgccgtgaa cgccaaggcg
    44161 ccgtacttcc tcgtgcagcg cgcgatcggg cagatgccca gcggcgggcg catcgtgaac
    44221 atcacctcgg gcgtcacccg caccgccgtc cccgaccagc tggcgtacgc catgaccaag
    44281 ggcgcgatcg agcagctcac cttccacctg gcgcggatcc tcgccccgcg cggcatcacc
    44341 atcaacagcg tggcgccggg catcacggac aacggcagcg ccctcttcga caaccccgag
    44401 gccgtcaagg cgatggccca gctgtcggcc ttcaaccggg tcggcgaggc cggtgacgtc
    44461 gccgacgtca tcaccttcct caccaccgac gaggcccgct ggatcacggg cgccttcatc
    44521 gacgccaccg gcggcaccct cagctgagcc acccgcaccc gtttccaccc gtgagaggga
    44581 gtcatgtccg ccaagacccc ccgctacgcc gtcgtcaccg gcggcaacaa gggcatcggc
    44641 cgcgagatcg tccggcagct cgccgagcgc ggcctggtcg tctacctcgg cgcccgcgac
    44701 gagcagcgtg gccgcgccgc cgagagcgac ctgcgcgccg acggcctcga cgtgcggttc
    44761 ctgcacctcg acgtcaccga cgacaagagc gtcgccctcg ccgccgaacg gctgcacgag
    44821 gaggcaggcg tcctgcacgt cctggtcaac aacgccggca tcggcggccc catgcagccg
    44881 cccagcgaga cccccaccga gcaggtgcgc acggtctacg agaccaacgt gttcggcgtc
    44941 atcaccgtca ccaacgcgct gctgcccctg ctgcgccggg ccggttccgc ccggatcgtc
    45001 aacgtcagca gcgccatcgg ctccctgtcg gcggcggccg cgaaccacga cccgacgggc
    45061 gtgcacccgc cgggcgagtt ccccgtcatg ctgtcgtacg ccacctccaa gagcgcgctc
    45121 aacgcggtca ccctgacgta cgccaacgaa ctgcgcggca ccggcatcct cgtcaacgcg
    45181 gcctcgccgg gattcgtcgc caccgacatc aacgggcacc acggcgtgct caccccgcag
    45241 cagggcgcac gcatccccgt gctgctggcg accctcggcg acgacgggcc gaccgccgcc
    45301 ttcctcggcg aggacggcac ccccgagggg caggtgctgc cctggtgacc ggcgccctcc
    45361 tcgacccgcc cgcggtgcgg gccggctgga cggcacggca gtggaccagg ctgctggtgc
    45421 tgtccggcaa catgctgctg gacgccgtcg aggtgtccgt cgtgctgatc gccctgcccg
    45481 ccgtcgccgc ccggtacggc ctcacgccct ggggcgccca gtggctgatg agcggcttcg
    45541 cgctcggctt cgccgcgctg ctgctgctcg gcccggccct gtgcgcccgc atcgggcggc
    45601 ggcgcgccta cctgggcgcc atgctgctgt tcgtcctcgc ctccctcgcg ggcggcgtcg
    45661 tcgacggccc ggcgctcctg gtggccgtcc gggtggtcaa gggctgctgc gcggccctga
    45721 ccgcaccgat gggcctcgcc ctcatcaacg acctgttccc cgagggtccc gagcggcggc
    45781 gggcgctgtc ggtctactcg ctgtccggcg cggccggctt caccgccggc ctgctgctcg
    45841 ccggtgcgct gctggcgagc gactggcgct gggtgttcgt cttccccgcg cccgtcgccc
    45901 tggtgctgct ggtgtgcggg ctgttcgtcc tgccgcgcgg gcggggcggc accccgcccg
    45961 ggccgccgcg cccggcgctg ctgaagcagg gggcgctgct gcgctccgcg ctgggcgccg
    46021 cctcgctcaa cggcacctac caggccctgc tggtgctgat ggtcttccag atgcacgacg
    46081 actttggctg gagcgcctgg cggaccgccc tcgccctgct gcccgcgtgc gtcccgctgg
    46141 cgctgaccgt ccccttcgcg ggccggttca tcgcccggta cggcacccgc cggctcatcg
    46201 ccgccggcgc gctcttcccg ctcctcggct acggcctctg tctggcccgg ccggacggca
    46261 gcccgtacgc cgtcggcacg ctgccggtcc tgctgctggt cgaggcgggc ttctgctgcg
    46321 cgttcgtcgc cctgaacgcg caggcgacgg cgggcttcga ggccgccgac cggggcgcgg
    46381 cggtgtcgtt gtaccagacg tgcgtccagc tcggcgccgc ggtgctgctg cccctggtgg
    46441 cgctgctcct gacccacggc gacggccccc gccccgccct ggccctcatc acggccgtag
    46501 gggccctggg cctcgccgcc gccctggcac accgcccggc ccgcagcggg cggtgacccg
    46561 cactccgacc cgttcaccac cccacgcacg cccttcgccc cccacagctc acccccaccc
    46621 cccacgccca ccactccacc ttcaccacca cggaggcata ccgaccatgg ccgacgtagc
    46681 gcacgagagc gccccgaacc ccggcccgat catggggctg atcctcggcg cctggcagtc
    46741 gcgcatgctg ctggcagccg tcgagcacga catcttcacc gaactgtcca agggagcggc
    46801 gacctccgcc gaactggccg ggcggatcgg cctggtggag cgccccacca acgacctgct
    46861 cgccggcctc gcccacctcg ggctgctgga gtcggcggac ggcacgttca ccaactccgc
    46921 cgtcgccgac gccttcctgg tccgcggccg gcccgcctac ctcggcggct acctgcactt
    46981 ctgcgagcag gagctgaacc cggcgtggaa cggcctggcc gactcgctgc gcaccggccg
    47041 gccgcagaac cgggccgccg tggagggcaa cccgtacgac accctgtacg cggacgccga
    47101 cgccaccgac ggcttcctgg acagcatgga cctgctcaac gcgccgatcg cggcggccct
    47161 gagccgcttc gactggagcg gctacacctc cttcgtcgac atcggtggcg cccgcggcaa
    47221 cttcgcgcac cagatcgtca cccacaaccc ccacctcaag ggcgccgtct tcgacctgcc
    47281 gcccctggag ccggcctttc gccggcacat ggaccgcctc ggcgacaccc cggcgccgat
    47341 caccttccac ggcggcgact tcttcaagga cgacctgccc gcggccgacg tcctggtctt
    47401 cggccacgtg ctgcacaact ggggcgtcga cgaccgcgtg acgctgctga agcgggccta
    47461 cgacgcgctg aagcccggcg gcgccgtctt cgtctacgac ccgatggccg gcgggcagca
    47521 gccgtcgatg cacggcgcgc tggccggtct caccatgctc gtctggtccc gcggcggcca
    47581 cgagtacacc gccgacgaac tccacggctg gctgcgcgag gcgggcttct ggccggagac
    47641 cgtcgaggtc gacggcctgc acgacgacgt cctggtcatc ggccgcaagg ccgagtgacg
    47701 cccttggaac cccaggagcc caccatgccc cgcacatccg acacccggcc ggtcctcggc
    47761 cgtcccgacg ccaccgcagc gctggtcgag gaggtcgtcg acggcgaccc cgagaagctg
    47821 cgggccgcca ccgccgcggt cctgcggcac tgggactccg ccgagtggcc ggcgggcctg
    47881 ctggccgtgt ccctgttcac cggcaccgac gacacgtcgc tgctggtcta ctcgcagtgg
    47941 tcggcgcgcg ccgggcacgg cgacgacctg ccggcggcgt tcgacgccct gcggcccgac
    48001 tggcgggcgc tgggctacac ccccggcgag ccccgggtgt tcgagctgta ccggcgggtg
    48061 cagccggccg tactgcccga tccgctgccg cccgtcgggt gctacccggc cgcgttcttc
    48121 tcgatgaacg acggccagac ggcccgcgcc tgggtcgacg gcctgctcgg caccgaggag
    48181 gagaccatcg gcgaggaccg cgcctacccc ggggccatcg ccgccaactt ccacgtatcg
    48241 gcggacgact cgggcatctt cctgttgtcc gagtgggcct cggaggcgga ggcgctggtg
    48301 cacatcaagg cggagatcga gccgctcctg gagtacatgg ggcaggccga ggccggaccg
    48361 ggccgccgct acaccttcca cgccaccgcc gccacggccg gctgagaacc acacagacga
    48421 aggacagcat tgtgtctacc cgcgaagtcg tcttcggctt cggtgcgcac agcaccatcg
    48481 accaggggcc ggagctgctc gacatggccc ggctggccga ccgcgagggg ctcgacctct
    48541 tctccctctc cgaccacccc tacatcggcc agcgcctcga cgcgtacgcc accgtcgggt
    48601 tcgtcctcgg ccgcacccag cggctggccg ggttcgcgaa cgtgagcaat gtgccgctgc
    48661 ggcccccggc catgctggcg cgcaccgtga ccacgctgtc cgcgctctcc ggcggccgtg
    48721 tcgtgctcgg cttcggcgcc ggcgggctgt gggagcggat cgccgacatg ggccgggagc
    48781 cgctcacccc gggtgaggcc gtcgaggcct tcgaggaggc ggtcgtcctc atccggaagc
    48841 tgtgcggcgg cggcccgccg gtcaccttcg agggccgcca ctaccacgtg cggcagatcg
    48901 agcccgcccc ggtgcccgcg ccgccggtgt ggaccgggtc ggtgggccgc aagtccctgg
    48961 ccgccaccgg ccgggtggcc gacggctgga tccccggcca cgccgcggac tggctcagcc
    49021 cgcgctaccg ggcctcccgg cccgtcatcg acgaggcggc caaggccgtg ggccgcgacc
    49081 cgcgcgaggt ccgcaccatc ttcaacttcc ccggccggat caccgaccgg ccgctgtccg
    49141 tcacccgcga cccggacggc cgctggatcg gcggcagcgt cgagcagtgg gtggaggagc
    49201 tgaccggagc ggtcctcgaa cacgacgcgg gcggcttcat gctcttctcg ccccgcggcg
    49261 gcaccccgga catggcctcc ctcggccgct gggccggcca gatcgtcccg gcggtccgcg
    49321 aggccgtcgc ccggcaccgc ggccagtgac ctgccgcgtc ccgtaccccg gttctccgaa
    49381 ccccgtttca ccccccaact caccctgaat cacgaagggc tttccatgag caggctgaag
    49441 aacaagacgg cactcgtcac cggcgccagc cggggcatcg ggcgcggcat cgcgctccgg
    49501 ctggcccagg acggggcgct cgtcgcggtg aactactcgg ccaacgaggc cgcggcgaag
    49561 gagacggtgg ccctcatcga ggaggcgggc ggccgtgcct tcaccgtgca ggccgaactg
    49621 ggcaagcccg gcgcggtgga gcagctgctg gccggcgtgg aggccgggct ggtcgagcac
    49681 accggctccc ggacgctgga catcctcgtg aacaacgcag ccgccaccgg cttcgccggg
    49741 accggccccc actcggtcac cgaggagatc ctcgacaact gctacaacat caacgccaag
    49801 gcgccgttcc tgctcatcca gaaggcactg gacctgatcc ccgacggcgg ccacatcgtc
    49861 aacgtctcct ccggcgtcac gcactccgcg ttcccgatcc agatcgccta cgcgatgagc
    49921 aaggccgccc tggagcagat cacgctgcac atggccccgg tcctggcgcc gcggaacatc
    49981 accatcaaca cggtggcccc cggcatcacc aacaacggcg acccggtgtt cgaggacccc
    50041 gaggcggtca agcagatggc cgccctgtcg gtgttcaacc gggtcggcga ggtgtccgag
    50101 gtcgccgaca tcgtcgcgtt cgtcgcctcc gacgaggccc gctggatcac cggggcgttc
    50161 gtcgacgcca ccggcggcac ccttctgcgc tgaggagccc cgcatgcaca acgagattca
    50221 gtcggcggtg ggttacgccc acgccaagcc ggagaaggcg gaggagctgc gtgacctgct
    50281 cgtctccttc gccgagcggt cccgtgccga ggaaggctgc ctgggcagct ggatcaacca
    50341 ggacgcgggc gacccccacc tcttcgtctt ctacgagatc tgggcgacgc gcaaggacct
    50401 ggcccgccac ctggcgcagc cgtacatgaa ggagttcctg gccggccggg acgagtacct
    50461 ggccaaggag ctggaggtgc gccagctgca cctggccggc ccggccccgg agcccgcgga
    50521 gcccgccgac ccggccgaga tgaaccagcg gtacctggac gcctacgccg cccgcgacat
    50581 cgacgcgatc atggcggtct acgcgcccgg cgccgcggcc gtctgggagc ccggcaaggc
    50641 ggtcagcggt gccgaacacc gggcggccgt cgaggagttc ctcaagcggg agccgaagct
    50701 gtccgccgag gtccgcgaga gctacgtcgt cggcgacacc gccgcgctcg tcgtcgactg
    50761 gagcatcgag gtgcccggct cgcccgagat gaccggcacc ggacgcgggc tggacgtcct
    50821 gcggcgcaac gcccgcggcg agtggcgcta catcatcacc aacccgttcg ggagcctgtg
    50881 acatgaggat cgaaggcagc gtggccgtcg tcaccggtgc cgcgagcggt atcggcaagg
    50941 cgatcgcgga gcagctcgcc ctcgccggcg cccggggcgt ggtcgtctcc gacctcgacg
    51001 ccgagggcgc cgagaaggtg gccgccggca tcggcagcgc ggcgctggcc gtccaggccg
    51061 acgtcggcga ggaggcgtcc gtgcaggccc tcgtggcccg cgcccgggaa cggttcggcc
    51121 aggtggacat cttcgtctcc aacgccggac tcaccgtcac gggcagctac gacgcaccgg
    51181 acgaggactg gaagcgcgcg atgatcgtca acatgatgtc gcacgtgtac gccgcgcgtg
    51241 cggtgctccc ggccatgctg gaggccggcc ggggccatct cgtccagacg atcgccgcgt
    51301 gcggtgtcct caccgcgttc ggcgcggcgc cctacgtggt cgccaagcag ggcgccgtgg
    51361 cgttcgccga gtacctcgcc gtggagtacg gcgaccgggg catcggcgtg tcgtgcctgc
    51421 tgccccaggc ggtcaacacc ccgatgctgg ccgccagcgt cagcagcaac gagcagctgg
    51481 cccagctgaa gaagaactcc gaggtgctgg agccggagga cgtggcgcgg gccgccctcg
    51541 ccggcatcga ggagaaccgg ctgcacgtct tcacccacaa ggggtcggcg gagtccttcc
    51601 ggcagcgtgc cgcggacgcc gacgtgtggg cggcgcagat gcgcgccatc cgtcacggcg
    51661 gccgcccctg acgcctgacc gggcccgtca cccgcgggtg cggggcgccc acaccgcgcc
    51721 ccgcacccgg cccgccccgg cccgccaccc cctctcgtcc ggctcaccgg ccgccctcgg
    51781 ccggcccccg ccccggccgt cccgcgtctt tccgtttccc tcgccgtgcc cggttcctgg
    51841 cgcgcaggaa ggaaaatcat gtccgaggaa aaccttcagc tgaccgtgat catcggttcc
    51901 tcccgtgagg gccgcaccgg cccggccgtc gcgcgctggt tcgtcgcgga ggccgagtcc
    51961 tgtgccatgt tcgacgtcga cgtcctggac ctggccggcg tcgaactgcc gctgtccctg
    52021 acccaggacc ccgggtccga gtcggccgag ctgctcgccg cggtcggggc acgcctggag
    52081 tcggcggacg cgttcgtcgt catcaccccg gagtacaacc acagcttcac cgccccgatg
    52141 aagaacctga tcgactggca ccgcaccccg tggcaggcca agccgatcgg cttcgtctcc
    52201 tacggcggcc tctccggcgg tctgcgcgcc gtggagcagc tgcgccaggt cttcgccgag
    52261 ctgcacgccg ccaccatccg ggacaccgtc agcttccacg gcgtctggca gcacgtcggc
    52321 gaggacggcg tcctgcgcgc ccccgacgcg gccgtcccgg ccaaggtcat gctcgaaaag
    52381 ctccagtggt gggcggccgc gctcaaggac gcccgcaccc tccgcccgta cgccgcctga
    52441 tccccccgcc cgccgaggtc tccccatgga caagcagata cgcgtcaccg ccttcgccat
    52501 gaacaccccg acacacctgt cgccgggcac ctggcgccac ccggcgagcc agggccgccg
    52561 gtacaaggac ctgagttact ggaccgacct ggccaggacg ctggaacgcg gcctgttcga
    52621 cgggctgttc atcgcggacg tgctcggcgc gtacgacgtg tacgcgggca cccccgacgc
    52681 ggcgctgcgc ggaggcgccc aggtcccggt gaacgacccc atgatgctgg tctccgcgat
    52741 cgcgcacgtc acgcggcacc tcgggatcgc ggtcaccgcc tccacgtcgt acgagcaccc
    52801 ctacccgttc gcccgccgca tgtcgacgct ggaccacctc accggtggcc gcgtcgcctg
    52861 gaacatcgtc acctcctacc tggacagcgc cgcccgcaac atcggcctcg accggcaggt
    52921 cggacacgac gagcggtacg acatcgcgga cgagtacctg gaagtcgtct acaagctgtg
    52981 gcagggctcc tgggaggacg acgcggtccg ggccgacgac cactacgcgg accccgcgaa
    53041 gatccacccg atcgcccacg aaggccgctg gttcacggtg ccgggcatcc acctgtgcga
    53101 gccgtcccca cagcgcaccc ccctgctgtt ccaggccggc acctcgcacc gcggcaagga
    53161 cttcgccgcg cggcacgccg aggccgtgtt cgcggtggcg ccggaggcgg cgatgctccg
    53221 caagcaggtc gaggacctgc gcggccgggt cgccgcggcg ggccgcgacc cgcacgacat
    53281 caaggtgttc agcgggtgca cggtcatcac cggcgagacg gaggccgagg cccgggccaa
    53341 gtacgacgag taccgcagcc acatcgaccc cgagggcatg ctcgcgctgt tctccggctg
    53401 gctcggcttc gacctgtccc cgtacggcct cgacgacccg gtgcgggtgg tgcccaacca
    53461 cgccgtgcag tccatcgccg agaccctcgg ccagggcgac tggaccgtgc gcgacctgct
    53521 ggagcggctc gcgctcggcc atccgccggt gatcgtcggc gcaccggaca aggtcgccga
    53581 cgagatccag cagtggatcg aggagaccgg cgcggacgga ctgaacctgg gccatgtggt
    53641 cacgccctcg acctacgagg acttcgtcga cctcatcgtg cccgaactcc agcgccgcgg
    53701 cgcctacaag acgcagtacg ccgacggcac gctgcgccac aagttcttcg gccgcgggga
    53761 ccgcccggcg ctcactcacc ccggttcccg gtacacccac gcggcgctcg actagggaga
    53821 gcacatgagt tccatcaggg tggaggacgg ctacttcacg ctgttcaaca tctttcacac
    53881 cgacggcccc gaggcgcagc agctgctgtt cgaccagtgg cgcagcctgc cgccggcgca
    53941 cacccagccg ggtctggtct cgggcaactt ccaccgcggc ttcgacggcg cctcggtggt
    54001 caactacgcc cagtgggaga gccgcgccgc ctacgacgcc ttcatgagcg agcaggccac
    54061 gcggggccgg ctcggcagcg ccctcgccgt gtcccggctg gacagcatcg cctgcgaggt
    54121 cgtccacacc tgggacccgg cgccccggat ctcgctggac cagccctggt acaccgtggt
    54181 ggtcgtcgtc aagtcggctc ccgaggacca ggccgaggtc ctgaaagaga tgaccttcga
    54241 tccgccggag ctggccgaca ccccggggta cgtctcgcac gccgtgcacc ggggcctgtc
    54301 cggcgaacac gtcgtcaagt acgcccagtg gcgggacgag gagagcttcc gcgccttcgt
    54361 gagcaggccg caggagccgt ccccgctgga cgagctgtcc gtcgaggtcg agctgtactt
    54421 cggcgagatc gagtacatcc gggagcggtc gtgaccacca cagcaacctg gccggacgcg
    54481 cgggcgctgc agaccgcggc cgacacggcc gcccggcacg cggccgaggc ggacaccggc
    54541 ggcaggctcg ccgacgccac ggtgcgcgcc ctggccgagg ccggcttcac cgcggggttc
    54601 gcacccgtcg ggcagggcgg tgccggggcc accttcacgc ggatgacgga cgcggtggcg
    54661 gcgatcgggg agggctgcac ctccgccgcc tggatcgcct cgctctgggc gtacaacggg
    54721 cgtttcagcg cctacctgcc cgaggaggga cagcgggagg tctgggccaa ggggccggac
    54781 acccggctgg tcagctcgat ggtcgcggcc ggcgtcgagg ccgagcccgt ggacggcggc
    54841 tggcggatct cgggcagctg gctgtacgtc agcggcgtcg agttcgccga ctgggcgctg
    54901 gtcagctcgg cgcccccgcg cgagggcgac cgcaccatca gggtgttcgc cgtgccccgg
    54961 gactccttca cgtaccggga gacctggtcg acgctcggca tgcgcgccac cggcagccac
    55021 accctggtcg tggaggaggc gttcgtaccg gagtaccggt cgttcctctg ggacgacatg
    55081 cggcagggga acctgcccgt gcccgcggcg aattccggac acgatggcgc ggacggctcg
    55141 catatacggc cgaattccgg cacgccttcc tcggcaggcg cgggatcatt ttccggaccg
    55201 gcctccgcgt cgctttccgc tacgccttcg ggctcggcca ccggtccgct ttccggcgcc
    55261 gaatccggat cgctttccgg tgcggacgcc gtgtccgccg tgcattccgc gccgctgttc
    55321 gcggtgaacg gactcacgtt cgcggcgccg atcctcggcg cggcccggca ggccctgcgc
    55381 ctggtcgagg agcatctcgc ccagcagccc agcggggcac gcgcggcggc ccgcgagtcg
    55441 caccggatcg ccctcgcccg cgcggcgggg gagatcgacg cggcggcgct gctgctggcc
    55501 cgggtcgccg acaccgccga ccggggcctg ctccgggagg acggggtggc cgtgcgcagc
    55561 caccgcgaca gcacgctcgc ggtggaactc ctcgtcggcg cggtggaccg gctcttccgg
    55621 gtgaccggca cccgggggca ggccacctcc cacgccatgc agcgcatctg gcgggacgtc
    55681 cacggggccg gctcgcacgc cgcgctccag ttcgagccgg cggccctcgc ctacacccag
    55741 cggctcgtcg ccgcctgacg cccgctcagc cgccggggga ggcctggtcc ggctcggcga
    55801 agaccgccgg caccttgtgg tccagcacga tccggccgag cagaccggcc agcgtgtcgc
    55861 gctcggccgg atccaggccg gccggcagct cctcgatgcg ccggcaggcc tcggtgtaga
    55921 agcggtcggc gagccgcgcg ccccgcgggg tgagcgccac ccgcaccgcg cggctgtccc
    55981 gcgggtccgg ctcacgccgt accaggccgt tgttctccgt acggtccacc agaccggtca
    56041 ggctcgactt ggccaggccc agcatcgagc acagctcgcc catgccgtag ggctgggcca
    56101 tcaggacaca cagcaactga ccctgctgcg gggtgaggcc gtcgtcgcgg gccgcctggg
    56161 catacacggc atgcaccagg aacgaggagc gcaccagcgc cgccaccagc cccatcccgc
    56221 cgtcttcacg cttagccacg cgcgcagcgt accacggaaa accgggaaag ttcgctgcca
    56281 gaactatcag ggatctgtca gaaatccgct gaacatttct ctgtagttgc ttaacaaaga
    56341 tctgtagttc ttgaaactct cattggttgt ggttcgtact gcgaaccagt acgttctcca
    56401 ctcgaacccg aagctttttc ctggtctctg gagtgtgaat catgagtcgt acagtcgctg
    56461 tcgtcggcgg tggctacggg ggcgccgcgg tggccaaggc gctggagtcc gaggccgacg
    56521 tcgtcctcat cgacccccgg gacgcgttcg tgaacgtcgc gggttcgctg cgcgcggtga
    56581 cccagcccga ctgggcggcc aacatgttct acccgttcag caccctgctc acgaagggca
    56641 agctggtccg cgaccgggcc gtctccgtcg accccgccgg cgtcacgctg tcctcgggcg
    56701 agcgcgtcgc cgcggactac gtcgtcctgg ccaccggctc caactacccc tacccggcca
    56761 accccacggc cgacacggtc acggaggcgc tggaggactt ccgccgctcg cacaaggagc
    56821 tgcgccaggc cgacaggatc ctgatcctcg gcgccggccc cgtcggcctc gaactcgccg
    56881 gtgagatcaa ggagatctgg ccggacaaga aggtcaccat cgtcgacccg gccaccgagc
    56941 tgctgcccgg cttcaagccc gaggtggtcg aggacctgcg cggccagctc gacgcgctcg
    57001 gcgtcgaggt gcggctcggc aacagcctga cggcccagcc gggcacggag gcgggcgtcg
    57061 ccggctcctt caccgtcacc accaccgacg gcgacgagat caccgccgac gtctggtacc
    57121 gcgcctacgg caccaccgtc aacagcggct acctctccga cggcaagctc accaccctca
    57181 ccccggccgg ccaggtcgag gtgacggaga agctcaacgt caagggctac gaccacgtct
    57241 acgccatcgg cgacctgacc gacgtcgcgg agaacaagat ggccggcttc gcgatgcagc
    57301 acgccgaggt cgtcgccaag aacatcatcg cccagatcaa gggcgaggag ccgacggcca
    57361 cctaccagcc gctgggcttc ccgatgatcc tgctcccgct cggcaccaag ggtggcgtgg
    57421 gccagctgcc ctcgccggac ggcccgttcg tcgccccggc ctccatggtc tccgagttca
    57481 agggcagcga cctgttcacc ggccgcttcg tcggccagtt cggccccacc gccgcctcct
    57541 gatccgacgc ggcctcccgg cccgccgcgc gaacgcctcg ggtcccactg gaacttcccc
    57601 cggccagtgg acccggcgtt cgcgcggcgt tcgtgtttcc cgtgatcccg gccgccggca
    57661 tccacgccgg cggccgtggt gtgcgcggcc cggcccgttg ccgtagccgg cacctgactc
    57721 aggcacctcc gcgccgcgcc ttccagccgt agccgcgggc acagccgtcg ccatcgccgc
    57781 agccgtggcc atcgccgcag ccgtcgccat cgccgcagcc gtggcccgcg gccttccgcc
    57841 gtggtgtctg ccgcagctgt ccggcccttc cggcggctcc tccggccctt ccggcccccc
    57901 ggcccggctc ctccggctcc cggccccctt tgccccggcc ccgccgcgcg catcgttgcc
    57961 gtccggcagc ttccctcccc ccactcatcg gcgtcccacg ccgcgtcctc accttcccgg
    58021 agacacccat gtcaccttcc gcatccgcgg accacacagc cgtaccggct tccgcagaga
    58081 cgttcctgcg tatcgagaag ggcagccccg acgccacgga actcgccgcg ctcacctcgg
    58141 tgctgctcgc ccgtgcggcc gtcctggcga acgcggacga ggagacggag cagacacccc
    58201 gccgcaccgc gggctggcgc cgcctcgaac ggcgctcgcg cgccggcacg ccccgcagct
    58261 ggcgcgacga cacgcgccgc tgatggggca cgcgccaggc cgggcccgcg tccgtctccc
    58321 cgcccggaaa ccccgcagcc ctcggaggtg ttgatccatg tcccagccgt cgcccgccga
    58381 cgcctccccg gtccgtgaca tcaccctcga cgccgacggc atccccctct ccggtctcct
    58441 cgccgaagcg cggcacggcc cgcccagggc cgtcgtggtc gcggtgcacg gcggcggcat
    58501 gtccgcgggc tacttccaca gccaggtccg ccccggcctc tccctgctca ccctcggcgc
    58561 cgacctcggc tacacggtcc tcgccatcga ccgccccggc tacggcagtt cggccgcctg
    58621 gctgccccgc ggccagaccc tcgccgacca ggcggcgacc ttccacgacg ccctcgaatc
    58681 cttcgcggcc acgcacgaca ccggcgccgg cctcttcgtc gtagcgcact ccaacggtgg
    58741 caagctcgcc ctcgccgcag ccgccgagga gcgcggcggc accctgctcg gcctggacat
    58801 ctccggcctc ggctgccggc tcgccgtgcg cagggaccaa ctcccgggac tgaacgggca
    58861 cggcgactgg cggcgccact ggggctcgct gcgcctgtac ccgccggacg ccttccggca
    58921 gggccgtcac ctgatctccc cggtgcccga actggaggcg caggagggcc cgtcgtggcc
    58981 ccggatgtat ccggacatcg cccgcagggt gcggacgccc gtccgtttca ccttcgccga
    59041 gcaggagcaa tggtggcggt tcgacgacga ggccgtggcc gcgctcaggg aaccgctggt
    59101 cgcgccgaag gtgctcgtcg accaccagcc ggacgccgga cacaacctca gcctcggctg
    59161 ggcggcccgc acctaccacc tcaaggcgct cggcttcctc gaggactgcc tgctcgccag
    59221 ggacgcggca ccggcccatc cacgcctgcg gcagcgcgag ccgatcgccg catcctgagc
    59281 cggccctgag cccgccctga cccggcccac agaccacccg tccgcccccc tccagccgcc
    59341 gcgcccaccc gatcggagaa caccacaccg aacaccacac caccggaaga caggcacagc
    59401 agatgaccat cgacaccctt gaaccggagc tggtgtccca ccgccagacc ccggacgagc
    59461 cccagcccgt ggccgcacag cccgtcgtcg tgcgccccgc gctcctcgcg ggggaggagc
    59521 acgaagcgcc ggacccgtgg atcttccgcg gcaccgactg aaccggccac gggcgtaccc
    59581 accgccgtca tcaccacccc ttcgccaccc accacccagg agagacatgt cccgccgcct
    59641 gttcacctcg gagtccgtga ccgagggcca tcccgacaag atcgcggacc agatcagcga
    59701 cgcgatcctc gacgaactcc tgcgccagga ccccacctcg cgcgtagccg tggaaaccct
    59761 gatcaccacc ggccaggtgc acatcgccgg cgaggtgacg acggccgggt acgccgacat
    59821 cgccgcgctc gtccgcgaga cgatcctgag gatcggctac gactcctccg ccaagggctt
    59881 cgacggcgcc tcctgcggcg tctccgtctc cctcggcgcc cagtccccgg acatcgcaca
    59941 gggcgtggac gccgcgtacg aggcccgggt cgagggcgac gacgacgagc tggacaagca
    60001 gggcgccggc gaccagggcc tgatgttcgg ttacgccacc gacgagacgc ccacgctgat
    60061 gccgctgccg atcgagctgg cgcaccgcct gtcccgccgt ctcgccgagg tccgcaagga
    60121 cggcacgctc ccctacctgc gccccgacgg caagacccag gtcaccatcg agtacctggg
    60181 caaccgcccg gtccgcctgg acaccgtcgt cgtctcctcc cagcacgccc ccggcatcga
    60241 cctggacggg ctgctcgtcc ccgacatccg cacgcacgtg gtggaacccg tgctgaacgc
    60301 gctggccgag gacgacatca aactggagac cgaggaccac cgcctgctgg tcaacccgac
    60361 cggccgcttc gagatcggcg gtccgatggg cgacgcgggc ctgaccggcc gcaagatcat
    60421 catcgacacg tacggcgggt acgcccggca cggcggcggc gccttctccg gcaaggaccc
    60481 gtccaaggtg gaccgctcgg cggcgtacgc gatgcgctgg gtcgccaaga acgtcgtcgc
    60541 cgcgggcctc gcctcgcgct gcgaggtgca ggtcgcgtac gccatcggca aggccgagcc
    60601 cgtcggcctg ttcgtggaga ccttcggcac cggcaccgtc gcgcaggagc ggatcgagcg
    60661 ggccatcgcc gaggtcttcg acctgcggcc ggccgcgatc atccgcgacc tggacctgct
    60721 gcgcccgatc tacgcgcaga cggccgccta cggccacttc ggccgcgagc tgcccgactt
    60781 cacctgggag cgcaccgacc gggccgaggc actcaaggcc gccgcgggcg tctgacgcct
    60841 ccccacgcag gaaacacaca gccccctccc cagccggccg ggtggccggc cgacgccggc
    60901 cacccgccag gagtgcagga gttcaagtgc gtatcgcggt gacaggatcc atcgccaccg
    60961 accatctcat ggtcttcccc ggccggttcg ccgaccagct cctcccggac cggctcgccc
    61021 gcgtctccct gtccttcctg gtcgacgccc tggaggtgcg ccggggcgga gtcgcggcca
    61081 acatcgccta cggcctcggc agcctcggtc tcgaccccct gctggtcggg gccgtgggca
    61141 gcgacttcgc ggagtacgcg gtctggctca aggaccacgg cgtcgacacc ggcgccgtac
    61201 agatctccgc cgagcgggcg accgcgcggt tcatgtgcat caccgacgag gacgccaacc
    61261 agatcgcctc gttctacgcg ggcgccatgc aggaggcccg cgacatcgac ctggggcggg
    61321 tgctcgccgg ccgcccgctg cccgacctgg tcctcgtcgg ccccaacgac ccggaggcga
    61381 tgctccggca cacccgcgag tgccgggccc tcggcctgtc cttcgccgcc gacccctccc
    61441 agcagctcgc ccgcctcacc ggcgcgcagg cgcgcgacct ggtgaccggc gcccgctggc
    61501 tcttcacgaa cgagtacgag gccgccctgc tcctcgaacg caccggctgg gaccacgacg
    61561 acgtcctcac ccgcgtcggc gcctggatca cgaccctggg cggcgacggc gtgcgcgtcg
    61621 agagcgccgg cgaacccccg ctcaccgtcc cggccgtccc cgacacgccg gtcacggatc
    61681 cgaccggcgt cggtgacgcc ttccgggccg gcttcctcgc cgccctcagc cgccggctcc
    61741 cgctgcccgc cgccgcccgg ctgggctgcg tggtggcgtc ggcggccctc gccacggtcg
    61801 gctcgcaggc ctaccgcatc gaccctgagc acctcctgac caccgccgca cgcgcctacg
    61861 gcgccgacgc ggcccgagaa ctcgccccgg ccctggacgg cacgccatga caccatcccg
    61921 cagcgcagac ctccgcgagg cgctcgccac ccgtgtggtg gtagccgacg gtgccatggg
    61981 caccatgctc caggcgcagg agcccagcat ggaggacttc cagcagctgg agggctgcaa
    62041 cgaggtcctc aacgtcaccc gcccggacat cgtccgctcg gtccacgcgg cgtacttcga
    62101 cgccggtgtg gactgcgtgg agaccaacac cttcggcgcc aaccatgccg cgctggggga
    62161 gtacggcatc accgagcgca tcttcgaact gtccgaggcg ggcgcccgta tcgcccgcga
    62221 gacggccgac gacttcaccc ggcggaccgg ccggcagcgg tgggtcctgg gctcgatggg
    62281 ccccggcaca aagctgccca ccctcggcca caccaccttc gccgcgatcc gcgacgccta
    62341 tcagcgcaac gccgagggtc tcgtcacggg cggcgcggac gccctgctcg tggagacggc
    62401 ccaggacctg ctgcaggcca aggcggcgct cctcggcgcc cgccgggccc tggacgccct
    62461 cggcgcggac ctgccgctga tctgctccgt gacggtggag accacgggca cgatgctgct
    62521 cggctcggag atcggtgcgg cgctgacggc gctggagccg ctcggcatcg acatgatcgg
    62581 cctgaactgc gccaccggcc ccgccgagat gagcgagcac ctgcgtcatc tctcccacca
    62641 tgcgggcatc ttgttgtcgt gcatgccgaa cgccggcctg cccgccctca ccaaggaagg
    62701 cgcccggtac cccctgaccc cggccgaact cgccgatgcc caggaagggt tcgtccgcga
    62761 gtacggggtg tccctggtgg gcggttgctg cggcacgact cctgagcatc tgcgccaggt
    62821 ggtggagcgg gtgcgggggc tgtccccggc cgagcgcgat ccgcgaccgg agccgggtgc
    62881 ggcttccctc taccagagtg tcccgttccg tcaggacacc tcctacctgg cgatcggtga
    62941 gcgcaccaac gcgaacgggt cgaagaagtt ccgtgaggcg atgctggagg gccgctggga
    63001 cgactgtgtg gagatggccc gggagcagat ccgtgagggc gcgcacatgc tcgatctgtg
    63061 cgtggactac gtcggccgtg acggcgtggc ggacatggag gagctggccg gccggttcgc
    63121 gaccgcctcg acgctgccgg tcgtgctgga ctccaccgag gtggaggtga tccgggccgg
    63181 gctggagaag ctgggcggcc gggcggtgat caactcggtg aactacgagg acggcgacgg
    63241 cccggagtcc cgtttcgccc gggtgacggc gctggcccgg gagcacgggg cggcgttgat
    63301 cgcgctgacc atcgacgagg agggccaggc ccgcacggcg gagaagaagg tcgagatcgc
    63361 ggagcggttg atcgcggacc tgaccgggaa ctgggggatc cgggaggagg acatcctcgt
    63421 cgactgcctg accttcacga tctgcacggg tcaggaggag tcccgcaagg acggcatcgc
    63481 cacgatcgag ggcatccgcg agctgaagcg ccggcatccg aacgtgcaga ccaccctggg
    63541 tctgtcgaac atctccttcg gcctgaaccc ggccgcccgc atcctgctga actcggtttt
    63601 cttggacgag tgtgtgaagg cggggctgga ttcggcgatc gtgcacgcct cgaagatcct
    63661 gccgatcgcc cggttcgacg aggagcaggt gcagaccgcc ctcgatctga tctacgaccg
    63721 tcgccgtgag ggctatgacc cgctgcagaa gctgatgcag ttgttcgagg gtgccaccgc
    63781 caagtcgctg aaggcctcga aggcgcagga gctggcggcg ctgccgctgg aggagcgcct
    63841 gaagcggcgc atcatcgacg gtgagaagaa cggcctggag gccgacctgg acgaggccct
    63901 cgccgcgcgt ccggcgctgg agatcgtcaa cgaggtgctg ctggacggca tgaaggtggt
    63961 cggtgagctg ttcggctccg gccagatgca gctgccgttc gtcctgcagt ccgccgaggt
    64021 gatgaagacc gcggtcgcct atctcgaacc ccacatggag aagaccgacg aggccggcaa
    64081 gggcaccatc gtgctcgcca ccgtgcgcgg cgacgtccac gacatcggca agaacctggt
    64141 cgacatcatc ctgtccaaca acggctacaa cgtggtcaac ctcggcatca agcagccggt
    64201 ctcggcgatc ctggaggccg cccaggagca caacgccgac gtgatcggca tgtccgggct
    64261 gctggtgaag tccaccgtga tcatgaagga gaacctggag gagctcaacg cccgcggcct
    64321 ggccgccgac tacccggtca tcctcggcgg cgccgcgctg acccgcgcgt atgtggagca
    64381 ggacctgcac gagatctacc agggcgaggt ccgctacgcc cgggacgcct tcgaggggct
    64441 gcggctgatg gacgccctga tcggcgtcaa gcgcggcgtc ccgggtgcgg tcctgccgga
    64501 gctgaagcag cgccgggtgc ggccgaccgc gcaggcggtg gtggaggagc ggccggagga
    64561 ggggcatgtc cgctcggacg tggccacgga caacccggtg cccgccccgc cgttcttcgg
    64621 cacccgcgtg atcaagggca tccagctcaa ggagtacgcc tcctggctcg acgagacggc
    64681 actgttccgt ggtcagtggg gcctgacgaa ggacctggtg gagacggagg gccggcccag
    64741 gctgcgcggc ctgctggacc ggctgcagac ggagaacctg ctggaggcgg ccgtcgtcta
    64801 cggctacttc cgctgcgtgt cgaagaacga cgacctgatc atcctggacg aggcgggcaa
    64861 cgagcgcacc cgcttcacct tcccgcgtca gcgccgcggc cgccggctct gcctggccga
    64921 cttcttccgc ccggaggagt ccggcgagac cgacgtcgtc ggcctgcagg tggtcaccgt
    64981 gggctcccgg atcggcgagg agaccgcgcg gctgttcgag gccgacgcct accgcgagta
    65041 cctcgaactg cacggcctgt ccgtccagct cgccgaggcc ctcgccgagt actggcacgc
    65101 ccgcgtgcgg caggaactcg gcatcgcggg cgccgacccg gacgcgctcg acggcatgtt
    65161 ccgcacggag taccagggct gccgctactc gctcggctac ccggcctgcc ccgacctgga
    65221 ggaccgcgcg aagatcgccg agctgctcca gcccgagcgg atcggcgtcc acctgtcgga
    65281 ggagttccag ctccaccccg agcagtccac cgacgccatc gtcgtccatc accccgaggc
    65341 cggctacttc aacgcgggag gcggacgggc atgaccacct tctccttcga gttcttcccg
    65401 ccgaagagcg agcagggcga acgcgtcctc tgggaggcga tccgccgggt ggagacgctg
    65461 caccccgact tcgtctccgt cacctacggc gcgggcgggt cgtcgcgtga ccggacggtg
    65521 gccgtgaccc gccgcatcgc cgccgagacc accctgcgcc cggtcgcgca cctcacggcg
    65581 gtcgggcact cggtggccga actgcgccac atcatcggcc agtacgccga cgccggcgtg
    65641 cgggacgtcc tcgccctgcg cggggatccg cccggggacc ccaagggtcc ctggaccccg
    65701 cacccggacg ggttcacgca cgcctggcag ctcgtcgaac tcgtgcggtc cctcggggac
    65761 ttcaccatcg gcgtggcggc gttcccggag atgcacccgc gctcgcccga ctgggagtcc
    65821 gacatccggc acttcgtcgc caagtgccgg gcgggtgccg actacgccat cacgcagatg
    65881 ttcttccacg tcgaggacta cctgcggctg cgcgaccggg tcgcggccgc gggctgcgac
    65941 atcccgatca tcccggagat catgccggcc accgactacc ggcagatccg ccgcttcgcc
    66001 gaactctccg acgcggcctt ccccgaggac ctggcccggc ggctgcacgc cgcgcgcggc
    66061 aacccggcgg ccggtcaccg catcggcgtg gagtacgcca ccgccatggc cgagcgcctg
    66121 ctcgccgagg gcgcccccgg actgcactac atcaccctca acaagtccac cgccgccctg
    66181 gacatccacc gcaccctcca gatcccaagg agcgtcagtg tccgctgact tcacggactt
    66241 caaggtcgcc gacctctccc tggccgagtt cggccgcaag gagatcaccc tcgccgagca
    66301 cgagatgccg ggcctgatgg cgatccgcaa ggagtacgcc gaggcacagc ccctcaaggg
    66361 cgcacgcatc accggttcgc tgcacatgac ggtgcagacg gccgtcctga tcgagaccct
    66421 ggtcgcgctg ggcgctcagg tccgctgggc gtcctgcaac atcttctcca cccaggacca
    66481 cgccgccgcc gcgatcgccg ccgccggcat tccggtgttc gcctggaagg gcgagacgct
    66541 ggaggagtac tggtggtgca cggagcaggc gctgacctgg ccgaacaccc ccaccggcgg
    66601 cccgaacatg atcctggacg acggcggtga cgccaccctc ctggtccaca agggcgtcga
    66661 gtaccagaag accggagagc tcccccctgc cgacaacgag gaactcgccg tcgtccgcgc
    66721 gctgctggag gccggcaccc tggactggac gcagctcgcg tccgagatcc gcggtgtgac
    66781 cgaggagacc acgacgggtg tgcaccgcct gtacgagatg cagcgtgacg gtgtcctgct
    66841 gttcccggcg atcaacgtga acgacgccgt gacgaagtcg aagttcgaca acaagtacgg
    66901 ctgccgtcac tcgctgatcg acggcatcaa ccgggccacc gacgtcctga tcggtggcaa
    66961 gaccgcggtc gtctgcggct acggcgacgt cggcaagggc tgcgcggagt cgctgcgggg
    67021 ccagggcgcc cgcgtcatcg tcacggagat cgacccgatc tgcgcgctgc aggcggcgat
    67081 ggacggctac caggtcacca cgctggacga ggtcatcgac aaggccgaca tcttcatcac
    67141 cacgaccggc aacaaggaca tcatcatggc ctcggacatg gccaagatga agcaccaggc
    67201 catcgtcggg aacatcggtc acttcgacaa cgagatcgac atggccggcc tggcgaagat
    67261 cccgggcatc gtcaaggacg aggtcaagcc gcaggtccac acctggacct tccccgacgg
    67321 caaggtgatc a
//
