LOCUS       NZ_BNBR01000003        21059 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces griseosporeus strain JCM 4766 sequence03, whole genome
            shotgun sequence.
ACCESSION   NZ_BNBR01000003
VERSION     NZ_BNBR01000003.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces griseosporeus
  ORGANISM  Streptomyces griseosporeus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 1004467)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 112X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014656055.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 05:04:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,365
            CDSs (total)                      :: 7,282
            Genes (coding)                    :: 7,186
            CDSs (with protein)               :: 7,186
            Genes (RNA)                       :: 83
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 96
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 96
            Pseudo Genes (frameshifted)       :: 41 of 96
            Pseudo Genes (incomplete)         :: 61 of 96
            Pseudo Genes (internal stop)      :: 11 of 96
            Pseudo Genes (multiple problems)  :: 15 of 96
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:46:46
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 543775
            Orig. end                         :: 564834
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BNBR01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21059
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21059
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21059
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11059](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11059)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    85..100
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.29"
                     /tool="antismash"
     misc_feature    110..123
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.7"
                     /tool="antismash"
     misc_feature    complement(255..270)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.63"
                     /tool="antismash"
     gene            365..1129
                     /locus_tag="IE308_RS17175"
                     /old_locus_tag="GCM10018783_35070"
     CDS             365..1129
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973740.1"
                     /locus_tag="IE308_RS17175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_35070"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_190218610.1"
                     /transl_table=11
                     /translation="MSTEVSSAENEGGATVRTARVPKYYRLKKHLLDMTETQAPGTPVP
                     PERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLTSYTEDMRA
                     QGLEPTSQLLDIGYITADDRLAGLLDITAGGRVLRIERLRMANGEPMAIETTHLSAKRF
                     PALRRSLAKYTSLYTALAEVYDVHLAEAEETIETSLATPREAGLLGTDVGLPMLMLSRH
                     SLDKDGNPVEWVRSVYRGDRYKFVARLKRPQD"
     gene            1282..1548
                     /locus_tag="IE308_RS17180"
                     /old_locus_tag="GCM10018783_35080"
     CDS             1282..1548
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992859.1"
                     /locus_tag="IE308_RS17180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_35080"
                     /product="DUF3311 domain-containing protein"
                     /protein_id="WP_110630426.1"
                     /transl_table=11
                     /translation="MSQAPEVSRGPVVTPVRVVIGLCLIAPFVAMLWVGSYAKTDPAFI
                     GIPFFYWYQMLWVVISTALTMIAYQLWRRDQRARASRKGGAEQ"
     gene            1545..3173
                     /gene="mctP"
                     /locus_tag="IE308_RS17185"
                     /old_locus_tag="GCM10018783_35090"
     CDS             1545..3173
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006848 - pyruvate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="mctP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674905.1"
                     /locus_tag="IE308_RS17185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_35090"
                     /product="monocarboxylate uptake permease MctP"
                     /protein_id="WP_190218611.1"
                     /transl_table=11
                     /translation="MKDGVNGVALGVFIFFFLLVTVLGFLAARWRKAENEHSLDEWGLG
                     GRSFGTWITWFLLGGDLYTAYTFVAVPAAIYAAGASGFFAVPYTILVYPLIFTFLPRLW
                     SVSHKHGYVTTSDFVRGRFGSKGLSLAVAVTGILATMPYIALQLVGIQAVLDVMGVGGG
                     EDTNWFVKDLPLLIAFGVLAAYTYSSGLRAPALIAFVKDTLIYIVIAVAIIYIPIKLGG
                     FDDIFAKAGEAFSQTNPATGKPKGALAPAEAGQWTYATLALGSALALFMYPHSITATLS
                     SRSREVIRRNTTILPLYSLMLGLLALLGFMAIAAGVKVQNGQLAIPQLFETMFPDWFAG
                     IAFAAIGIGALVPAAIMSIAAANLFTRNIYKDFIKPDATAQQETAVSKIVSLLVKVGAL
                     VFVLTMDKTVAINFQLLGGIWILQTFPALVGGLFTRWFHRWALLAGWAVGMVYGTMAAY
                     GVASPTQKHFGGSAKEIPGIGEIGYIGLTAFVLNVAVTVVLTFVLKAVKAPEGADETKP
                     EDYTADAGDPGVQVELPPATAGSAH"
     misc_feature    3243..3258
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.72"
                     /tool="antismash"
     gene            3244..3750
                     /locus_tag="IE308_RS17190"
                     /old_locus_tag="GCM10018783_35100"
     CDS             3244..3750
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326961.1"
                     /locus_tag="IE308_RS17190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_35100"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_190218612.1"
                     /transl_table=11
                     /translation="MDILIRPADPTEHAALGEITAQAYLGDGLLDFGADDPYLGELRDV
                     AKRAAAAEVLVAVDGDRLLGGVTFVPSGGPMADIARPGEAEIRMLAVDHAARGRGAGEA
                     LVRACVERARATRGCRAVVLSTQRTMHAAHRIYERLGFVRTPERDWNPVPELDDIMLHT
                     YELTL"
     misc_feature    3761..3775
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: strong, score: 25.12"
                     /tool="antismash"
     misc_feature    3792..3806
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.21"
                     /tool="antismash"
     misc_feature    3800..3813
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.46"
                     /tool="antismash"
     regulatory      3828..3905
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            4048..6405
                     /locus_tag="IE308_RS17195"
                     /old_locus_tag="GCM10018783_35110"
     CDS             4048..6405
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006378224.1"
                     /locus_tag="IE308_RS17195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_35110"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_190218613.1"
                     /transl_table=11
                     /translation="MTIAPADPASAIPAAEETDGPGTALLRTLTELTADLPDADPGRVA
                     AAALRGRSARADEAELRELATEAAAGLISEDPAYSRLAARLLTRTIRAEAASQGVTTFT
                     ESVAVGHREGLIADRTAEFVRLHAERLDALADPAADDRFGYFGLRTLHSRYLLRHPLTR
                     KVIETPQHFLLRVAAGLAEDDTTRALDEVADLYGLMSRLDYLPSSPTLFNSGTRHPQMS
                     SCYLLDSPLDELDSIYDRYHQVARLSKHAGGIGLSYSRIRSRGSLIRGTNGHSNGIVPF
                     LKTLDASVAAVNQGGRRKGAAAVYLETWHSDIEEFLELRDNTGEDARRTHNLNLAHWIP
                     DEFMRRVEADGQWSLFSPADVPELVDLWGEEFDAAYREAERKGLARKTLPARELYGRMM
                     RTLAQTGNGWMTFKDAANRTANQTAEPGHVVHSSNLCTEILEVTNDGETAVCNLGSINL
                     GAFVDGRDIDWERLDATVRTAVTFLDRVVDINFYPTEQAGRSNARWRPVGLGAMGLQDV
                     FFKLRLPFDSPEAKALSTRIAERIMLAAYEASADLAERNGPLPAWEKTRTARGVLHPDH
                     YDVDRTWPERWAALRERIARVGLRNSLLLAIAPTATIASIAGVYECIEPQVSNLFKRET
                     LSGEFLQVNSYLVQDLKELGVWDARTREALREANGSVQDFAWIPEDVRRLYRTAWEIPQ
                     RGLIDMAAARTPFLDQSQSLNLFLETPTIGKLSSMYAYAWKSGLKTTYYLRSRPATRIA
                     RAARAAVPAQPAADPEAVACSLENPESCEACQ"
     gene            6405..7418
                     /locus_tag="IE308_RS17200"
                     /old_locus_tag="GCM10018783_35120"
     CDS             6405..7418
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657910.1"
                     /locus_tag="IE308_RS17200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_35120"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_190218614.1"
                     /transl_table=11
                     /translation="MSPRNQNLLDPGFELTLRPMRYPDFYERYRDAIKNTWTVEEVDLH
                     SDVADLAKLTPGEQHLIGRLVAFFATGDSIVANNLVLTLYKHINSPEARLYLSRQLFEE
                     AVHVQFYLTLLDTYLPDPEERAAAFAAIENIPSIREKAQFCFKWMDSVEKIDRLETRAE
                     RRRFLLNLICFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMHMSFAFE
                     VVDTVRKEEPDLFDDRLQQEVTDMLREAVEAELQFARDLCGDGLPGMNTDSMRQYLECV
                     ADQRLTRLGFAPVYGSENPFAFMELQGVQELTNFFERRPSAYQVAVEGTVDLDEDF"
     gene            complement(7331..7555)
                     /locus_tag="IE308_RS17205"
                     /old_locus_tag="GCM10018783_35130"
     CDS             complement(7331..7555)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010047586.1"
                     /locus_tag="IE308_RS17205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_35130"
                     /product="hypothetical protein"
                     /protein_id="WP_190218615.1"
                     /transl_table=11
                     /translation="MNTIFSYATVLILAVVLTAPALVGWLHERRIDRQLAAAEAARTRP
                     AQKSSSRSTVPSTATWYAEGRRSKKLVSS"
     misc_feature    7540..7554
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.38"
                     /tool="antismash"
     gene            7648..8613
                     /locus_tag="IE308_RS17210"
                     /old_locus_tag="GCM10018783_35140"
     CDS             7648..8613
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018544423.1"
                     /locus_tag="IE308_RS17210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_35140"
                     /product="GlxA family transcriptional regulator"
                     /protein_id="WP_110637088.1"
                     /transl_table=11
                     /translation="MLKNVAAVLLDGVHPFELGVVCEVFGIDRSDEGLPTYDFAVVSAE
                     GSALTTHVGGLTLATPYGLERLEEADLIAVPAGDEYARREYPPELLDALVRGVERGARV
                     LSVCSGVFVLGAAGLLEGRRCAVHWHHAGELARQFPRAVVEPDVLYVDEDPVITSAGTA
                     AGIDACLHLVRKEQGPEVANKIARRMVVPPHRDGGQAQYIERPLPKSTCDTVGEVLAWM
                     EQHLDEEVTVEQLAARAHMSPRTFARRFQQETGTTPYRWILRQRVLLAQELLEATDETV
                     DAIAWRTGFGTAAALRHQFVRALGTTPQSYRRTFRGPQAA"
     gene            complement(8628..10004)
                     /locus_tag="IE308_RS17215"
                     /old_locus_tag="GCM10018783_35150"
     CDS             complement(8628..10004)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326965.1"
                     /locus_tag="IE308_RS17215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_35150"
                     /product="cytochrome P450"
                     /protein_id="WP_110630414.1"
                     /sec_met_domain="p450 (E-value: 6.1e-73, bitscore: 241.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVEQVKPETTGTPAPGLLEPPLAGGGVPLLGHGWPLLRDPLAFM
                     SRLRDHGEVVRLKLGPKTVYAVTTPALTGALALSPEYHIAGPLWESLEGLLGKKGVATA
                     NGPQHRRQRRTIQPAFRLDAIPAYGPIMEEEAHALTERWKPGETVDCTTESFRVAVRIA
                     ARCLLRGDYMDERAERLCTALATVFRGMYRRMVVPLGPLYRLPLPANREFNRALADLHL
                     LVDEIVAERRASGQKPDDLLTALLQAKDENGDPIDEQEIHDQVVAILTPGSETVASTIM
                     WLLQALAEHPEHADKVRDEVESVTGGRPVAFEDVRKLRHTNNVVVEAMRLRPAVWILTR
                     RAVTDTELGGYRIPAGADIVYSPYAIQRDPESYDRNLEFDPDRWLPERVKDIPKYAMSP
                     FSVGNRKCPSDHFSMAQLTLITAALATKYRFEQVSASDDTTRVGITLRPQNLLLRPVAR
                     "
     gene            complement(10001..11059)
                     /gene="cyc1"
                     /locus_tag="IE308_RS17220"
                     /old_locus_tag="GCM10018783_35160"
     CDS             complement(10001..11059)
                     /EC_number="4.2.3.37"
                     /GO_function="GO:0052680 - epi-isozizaene synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyc1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009190552.1"
                     /locus_tag="IE308_RS17220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_35160"
                     /product="epi-isozizaene synthase"
                     /protein_id="WP_373314511.1"
                     /sec_met_domain="T1TS (E-value: 1.4e-62, bitscore: 208.2,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPARVAVPPSLALPVIEAAFPRQLHPYWPRLQEKTRSWLLEKRL
                     MPADKVEEYADGLCYTDLMAGYYLGADDAVLQAIADYSTWFFVWDDRHDRYVVHGRTAA
                     WRTLRQALHAALESPGAHLHHPDPLVAGLADSVARLFAFLSDTWNARFTRHFHAVIDAY
                     DREFRNRTEGIVPTVEEYLELRRLTFAHWIWTDLLEPTAGRELPDGVRKHPAYRRAALL
                     SQEFAAWYNDLCSLPKEIAGDEVHNLGISLITHHGLTLEEAIEEVRRRVEECISEFLVA
                     EQEALRLADSLADGTVHGKELGAAVRACVANMRNWFSSVYWFHHESGRYMVDSWEDRST
                     PPYVTNEAAGEK"
     gene            complement(11402..12052)
                     /gene="def"
                     /locus_tag="IE308_RS17225"
                     /old_locus_tag="GCM10018783_35170"
     CDS             complement(11402..12052)
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="IE308_RS17225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_35170"
                     /product="peptide deformylase"
                     /protein_id="WP_110630410.1"
                     /transl_table=11
                     /translation="MAQQDTDQQHAGVLPVDDEGFVIDTEDCEEREQAYRERGTSRPIT
                     VVGNPVLHKECKDVTEFGDELRKLVDDMFASQRTAEGVGLAANQIGVDLKVFVYDCPDD
                     NGVRHVGVVCNPKLVELPADKRRLDDSNEGCLSVPTAYMPLARPDYAEVTGQDERGNPI
                     KVRGTGYFARCLQHETDHLYGYLYIDRLSKRERKDALRQMAENEPRYPVVAND"
     gene            complement(12124..13131)
                     /locus_tag="IE308_RS17230"
                     /old_locus_tag="GCM10018783_35180"
     CDS             complement(12124..13131)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889310.1"
                     /locus_tag="IE308_RS17230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_35180"
                     /product="hypothetical protein"
                     /protein_id="WP_190218617.1"
                     /transl_table=11
                     /translation="MRIFGKGRHRPSASWRQATDRAFTLIGDGRYEDAGALLTRAADLE
                     PWRSESWFNLALLHKFRHDWEQARAAGLRAVALLEKETGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLRVPGGGSRSQAGAGAAASGEPVGMDLGSAAVRLSPEGEAEVVWGRRLDPA
                     RIEVLSIPLPSSGRRWGEVVLHDGVPHGERTTSAGHSYPVFDEIELWAPSPVPTWVVLI
                     EAATEADRDALEQLAADAGFAAEDWSSSVRLLCRMCSESRMPADEGDGVHLDPHDHSEP
                     GHPGPLGHRTDGQLWVPERECGVAAPASLVRGLLDGWVADAPDSRDWRDLEEVC"
     gene            complement(13243..14466)
                     /locus_tag="IE308_RS17235"
                     /old_locus_tag="GCM10018783_35190"
     CDS             complement(13243..14466)
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136681.1"
                     /locus_tag="IE308_RS17235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_35190"
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_229908942.1"
                     /transl_table=11
                     /translation="MLVVVRGAAGLLVTVSVVVTLRTGPVERSLALAFGALVAVGELTR
                     WRGPQLREAAPLGAAGALAYALLGEAAGRPTHHGTAQVVTVVCAASLLGSVPHIARGQS
                     PTLDHLARRVLTVGFAAVCFQPLYNRGVFDSWVGPAYALLLVALLTLTALCDAVLAAAL
                     AHARTRWPFGPLLRDELRALAGIGSAVCATGAVMALAVAAAGLWALPVFCVPLLLTQLS
                     FRRYAAVRATYRQTIASLARATEIAGYTPAGHAHRVAALGLAVGRDLGLTEPELTVLEY
                     AALMHDIGQLSLVDPVPAGATAALPPAEQRRIALLGGAVVRQTGVNPQVATVVERQADP
                     YPEQPRAARIVRVVNAYEEKARDAGPGGALAALEELRLGAAGDYAPEVVEALARVLARG
                     SLTAPAAG"
     gene            complement(14535..15857)
                     /locus_tag="IE308_RS17240"
                     /old_locus_tag="GCM10018783_35200"
     CDS             complement(14535..15857)
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020119819.1"
                     /locus_tag="IE308_RS17240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_35200"
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_190218618.1"
                     /transl_table=11
                     /translation="MEAVPARARVYVAGVTVCACALLLPLPLPVPSVRSPGWAVALLAA
                     LYAAGEQLARRRLAGTFYPVLLAGAFLLPPPAAALVAVPGALLSHGVRRSVQLRRVWRA
                     AQLVVAVWAAARVHGALGGRDAVVTPDFPYVLGPAGAAVLVFCLVLAVLDAGVLALADH
                     APVARTCRGVFGRSLAPVAVHGLAGLMMAVLWRSPYGPVAALLVLLPMYVSWWVFAQYH
                     RERAAHRATIRALVQAVDIKDGYTRGHSERVGRASMMIARELGLDDERVEVLRLAGILH
                     DVGKLGVPTRLLRKDGPLTPEERRVIELHPEYGHEITRGISFLGEARAAILHHHERLDG
                     SGYPYGLSGAQIPECARVVAVADAFDAMTSTRSYRRARPVATALEELRRCAGAQFDPDM
                     VEALTRALAREGWHPAVTAEEAAVPRPRRDAASHGRPGVRP"
     gene            complement(15972..16274)
                     /gene="rsrA"
                     /locus_tag="IE308_RS17245"
                     /old_locus_tag="GCM10018783_35210"
     CDS             complement(15972..16274)
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136687.1"
                     /locus_tag="IE308_RS17245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_35210"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_110630404.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCSEVLDHLYEFLDSEMPDVDRDKFQQHFKECSPCL
                     EKYGLEQAVKKLVKRCCGHDDVPTDLRAKVMGRIDLIRSGQAVPEHDVTATPQES"
     gene            complement(16271..16966)
                     /gene="sigR"
                     /locus_tag="IE308_RS17250"
                     /old_locus_tag="GCM10018783_35220"
     CDS             complement(16271..16966)
                     /codon_start=1
                     /gene="sigR"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="IE308_RS17250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_35220"
                     /product="RNA polymerase sigma factor SigR"
                     /protein_id="WP_190218619.1"
                     /transl_table=11
                     /translation="MGPVPGTDAGTDNGQAELPEGPGVSADAGAESTAERSARFERDAL
                     EFLDQMYSAALRMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINS
                     YRKKQREPQRSAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKEALQAIPEEF
                     RIAVYLADVEGFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARERGLVPAGAGE
                     SNEAKGSGS"
     gene            complement(17225..17863)
                     /locus_tag="IE308_RS17255"
                     /old_locus_tag="GCM10018783_35230"
     CDS             complement(17225..17863)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992844.1"
                     /locus_tag="IE308_RS17255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_35230"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_190218620.1"
                     /transl_table=11
                     /translation="MTHTTQETVETEAGPARITWHTARKARLVLAISHGAGGGIEARDL
                     QALARVLPGHGVTVALVEQPWRVAGKKVAPAPKTLDTGWRGLWPALTRPGPPVIAGGRS
                     AGARVACRTAAELGAHAVLALSFPLHPPGRPEKSRAEELLGAGVPTLVVQGGNDPFGRP
                     DEFPDGPYELVEVPYGDHGFAVPKRAPIGQDEAVTVITDAVVKWTGSLG"
     gene            complement(17865..18680)
                     /locus_tag="IE308_RS17260"
                     /old_locus_tag="GCM10018783_35240"
     CDS             complement(17865..18680)
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="IE308_RS17260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_35240"
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_190218621.1"
                     /transl_table=11
                     /translation="MCGRYASSRRPEDLAGIFEIEKWEPEETLAPDYNVAPTKEVYAVL
                     DRPLKDAAEPRPVRQLRKLKWGLVPSWAKTPEGGARMINARAETVHEKPSYRRAFTSRR
                     CILPADGYFEWVTGVQERELEVEGRKKRPRKQPYFVLPADGSVFAMAGVYEFWRDRTLP
                     DDHPQAWWATCSVITTEAETSPLAVAPAEGPHSLADIHPRMPLMLTPDRWDAWLDPART
                     DPDDLRELLAPPPPGLMRAYPVSTAVSNVRNNGPELLKELEAPEEGTLF"
     gene            18731..19444
                     /locus_tag="IE308_RS17265"
                     /old_locus_tag="GCM10018783_35250"
     CDS             18731..19444
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136691.1"
                     /locus_tag="IE308_RS17265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_35250"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_190218622.1"
                     /transl_table=11
                     /translation="MDTSTATSLWDELVGTQSEPDLWVVIATGVAALAVVVPQAVWRVA
                     RNAITIAHEGGHGLVALLTGRQLTGIRLHSDTSGLTVSRGKPYGLGMILTAVAGYTAPP
                     LLGLGGAALLAAGRITLLLWLATALLLAMLVMIRNAYGALTVVLTGTLFVLVSWLTGPQ
                     VQAAFAYAVVWFLLLGGVRPAFELQAKRRHGGAGDSDADQLARLTHTPAGLWLFLFHAV
                     SLCSLLGGGRWLLGV"
     gene            19557..20873
                     /gene="aroA"
                     /locus_tag="IE308_RS17270"
                     /old_locus_tag="GCM10018783_35260"
     CDS             19557..20873
                     /EC_number="2.5.1.19"
                     /GO_function="GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="aroA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016824681.1"
                     /locus_tag="IE308_RS17270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_35260"
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="WP_110630394.1"
                     /transl_table=11
                     /translation="MVPNAASTALWPAPHASGAVDATVHVPGSKSVTNRALVLAALASE
                     PGWLRRPLRSRDTLLMAGALRAMGIEIEEGVGPDGTGEAWRVLPTGLRGPATVDVGNAG
                     TVMRFLPPVATLADGPIRFDGDPRSYERPLHGVIDALRALGARIDDDGRGALPMTVHGG
                     GALDGGVVEIDASSSSQFVSALLLSAPRFNQGVEVRHVGSTLPSMPHIRMTVDMLRAVG
                     AQVDTPESGGEPNVWRVTPGALLGRDLTIEPDLSNAQPFLAAALVTGGRVVIPDWPART
                     TQPGDRLREIFTEMGGSCELADYGLVFTGSGAIHGIDVDLSEVGELTPGIAAVAALADS
                     PSTLRGVAHLRLHETDRLAALTKEINELGGDVTETADGLHIRPRPLHGGVFHTYEDHRM
                     ATAGAVIGLAVEGVRIENVATTAKTLPDFPELWTGMLGA"
ORIGIN
        1 ccctcctcag ggatgcacac gaacccccct gcctccccgc ggtgaacgtc gaacgcgaac
       61 cgcccatggg gccgggactg gaccaatggt gtagaccagt acggggagct tggcccagac
      121 caaagggtgt gtcaagggtg cgcgaatccg ctccgaccag ccgttatgcg acctacatat
      181 gcaggaacct ttaagtaaga accccgcgaa aagacgccga cttgcggcac actccaggta
      241 gaccacttgg cagcgatgga ctagaccaaa acagcggccg agggtataca gaggagatca
      301 cggaacgcgc gggcggccga tggtgtgtcg gccgcttcgg caccgagggc cgggaaggca
      361 gagcatgagc accgaggtca gcagtgcgga gaacgagggt ggggcgaccg tccgtaccgc
      421 gcgtgtgccc aagtactacc gcttgaagaa gcacctgctc gacatgacgg agacgcaggc
      481 gcccggcaca ccggtgccac ccgagcgcac gctggccgcc gagttcgaca cctcccgcac
      541 gaccgtccgg caggccctgc aggaactggt cgtcgagggc cgcctggagc gcatccaggg
      601 caagggcacg ttcgtcgcca agccgaaggt ctcccaggcg ctgcagctca cctcgtacac
      661 cgaggacatg cgcgcgcagg gcctggagcc cacctcgcag ctgctggaca tcggctacat
      721 caccgcggac gaccggctcg ccggcctgct cgacatcacc gcgggcgggc gggtgctgcg
      781 catcgagcgg ctgcgcatgg ccaacggcga gccgatggcc atcgagacca cccacctgtc
      841 cgccaagcgc ttcccggcgc tgcgccggtc gctggccaag tacacctccc tgtacaccgc
      901 cctcgccgag gtctacgacg tccatctcgc cgaggccgag gagaccatcg agacctccct
      961 cgccaccccg cgcgaggcgg gcctgctcgg caccgacgtg ggcctgccga tgctgatgct
     1021 gtcccggcac tccctggaca aggacggcaa tccggtcgaa tgggtgcggt cggtctaccg
     1081 cggggacagg tacaagttcg tggcgaggtt gaagaggccc caggactgac gccccgtgag
     1141 aaggcctccg acgccgctca ccgggcggcc ttcccggact ttgcggaccg atatgcggac
     1201 ggggtcttcc taagtccttt atccgtcacc tacattgcgt ccctgtttcg caggtgatcg
     1261 gttaggggac ggagccgcct gatgtcgcaa gccccagaag tttccagagg gccggtggtg
     1321 acgcctgtgc gcgtcgtcat cggcctctgc ctgatcgcgc ccttcgtggc gatgctgtgg
     1381 gtcggttcgt acgccaagac ggacccggcc ttcatcggga tcccgttctt ctactggtac
     1441 cagatgctgt gggtggtcat ctccaccgcg ctgaccatga tcgcttacca gctgtggcgg
     1501 cgtgaccagc gcgcccgcgc gtcccggaag ggtggtgcgg agcagtgaag gacggcgtga
     1561 acggcgtcgc gctcggcgtc ttcatcttct tcttcctcct cgtcaccgtc ctgggcttcc
     1621 tggccgcacg gtggcgcaag gccgagaacg agcacagcct ggacgaatgg ggcctgggcg
     1681 gacggtcgtt cggcacctgg atcacctggt tcctgctcgg cggcgacctc tacacggcgt
     1741 acacgttcgt cgccgtgcct gcggcgatct acgcggcggg cgcgtccggc ttcttcgcgg
     1801 tgccgtacac catcctcgtc tacccgctga tcttcacgtt cctgccgcgg ctgtggtcgg
     1861 tgtcgcacaa gcacggctat gtgacgacct cggacttcgt gcgcggccgg ttcggctcca
     1921 agggcctgtc gctggcggtg gcggtgaccg gcatcctggc gacgatgccg tacatcgcgc
     1981 tccagctcgt cggcatccag gcggtgctgg acgtgatggg cgtcggcggc ggcgaggaca
     2041 ccaactggtt cgtgaaggac ctgccgctgc tgatcgcgtt cggcgtgctc gcggcgtaca
     2101 cctactcctc gggtctgcgc gccccggcgc tcatcgcctt cgtgaaggac acgctgatct
     2161 acatcgtcat cgcggtggcg atcatctaca tcccgatcaa gctgggcggc ttcgacgaca
     2221 tcttcgccaa ggccggcgag gcgttctcgc agaccaaccc ggccaccggc aagccgaagg
     2281 gcgccctcgc gccggcggag gccggccagt ggacgtacgc cacgctggcg ctgggctcgg
     2341 cgctcgcgct gttcatgtac ccgcactcga tcaccgcgac gctgtcctcg cgcagccgtg
     2401 aggtgatccg ccgcaacacc acgatcctgc cgctgtactc cctgatgctg ggcctgctcg
     2461 cgctgctcgg cttcatggcg atcgcggccg gggtgaaggt gcagaacggc cagctggcca
     2521 tcccgcagct gttcgagacg atgttcccgg actggttcgc gggcatcgcg ttcgcggcga
     2581 tcggcatcgg cgcgctggtc ccggcggcga tcatgtcgat cgcggcggcg aacctcttca
     2641 cccgcaacat ctacaaggac ttcatcaagc cggacgccac ggcccagcag gagaccgccg
     2701 tctccaagat cgtgtcgctg ctggtgaagg tcggcgcgct ggtcttcgtc ctcaccatgg
     2761 acaagacggt cgccatcaac ttccagctgc tcggcggcat ctggatcctg cagaccttcc
     2821 cggcgctggt cggcggcctg ttcacgcggt ggttccaccg ctgggcgctg ctcgccggct
     2881 gggcggtcgg catggtctac ggcacgatgg ccgcgtacgg cgtcgcctcg ccgacgcaga
     2941 agcacttcgg cggctcggcg aaggagatcc cgggcatcgg cgaaatcggc tacatcggtc
     3001 tgacggcgtt cgtgctgaac gtcgcggtga cggtggtgct gaccttcgtc ctgaaggccg
     3061 tgaaggcccc cgagggcgcc gacgagacga agccggagga ctacacggcc gacgcgggcg
     3121 accccggcgt ccaggtggaa cttccgccgg ccaccgcggg aagcgcgcac tgacccctct
     3181 ccactcccag cgggccgccg aaagcagctg cttcggcggc ccgttgtcgt ccacactccc
     3241 cccatggaca tccttatccg gcccgccgac cccaccgaac acgccgccct cggcgagatc
     3301 accgcgcagg cctatctcgg agacggtctg ctggacttcg gcgcggacga cccgtacctc
     3361 ggggagctga gggacgtcgc gaagcgcgcc gccgccgcgg aggtgctggt cgccgtcgac
     3421 ggcgaccggc tgctcggcgg cgtcaccttc gtcccgtccg gcggtcccat ggccgacatc
     3481 gcccgccccg gcgaggcgga gatccgcatg ctcgcggtgg accacgcggc gcgcggccgg
     3541 ggcgccgggg aggcgctcgt gcgggcctgt gtcgagcgcg cgcgggccac gcggggctgc
     3601 cgggccgtcg tgctgtccac ccagcgcacc atgcacgccg cccaccggat ctacgaacgc
     3661 ctgggcttcg tccgcacccc cgagcgggac tggaatcccg tgccggagct cgacgacatc
     3721 atgctccaca cgtacgagtt gacgctctga caccacccgg acacaacatc tgggggtggc
     3781 acgacagccg ggcacaagat gtatgctcat gctcgctgtc gccgcagggg aatccggtgc
     3841 gaatccggaa ctgtcccgca acggtgtact tgtgtgcgtc tgcacgcctg ttcagtccga
     3901 ggacctgccg acagcgcacc cggtcgtccg gccggtgtgc ccgacgtccg ggcctcgcgg
     3961 aatgggccgg tggacgcgac gcccccgtgc gctcgtgctg ccccctgccc tcgccgaggc
     4021 cccgtgccga gcgagggagt gccccacgtg accatcgcgc cagccgaccc ggcttcagcg
     4081 atcccggcgg ccgaggagac cgacggtccc ggaaccgcgc tgctgcggac cctgaccgag
     4141 ctgaccgccg acctgcccga cgccgacccc ggccgggtcg ccgccgccgc cctgcggggc
     4201 cggtccgccc gggccgacga ggcggagctg cgcgagctgg ccacggaggc cgccgccggt
     4261 ctgatctccg aggaccccgc ctactcccgg ctggccgccc ggctgctcac ccgcaccatc
     4321 cgcgccgagg ccgcctccca gggcgtcacg acgttcaccg agtcggtcgc cgtcggccac
     4381 cgcgagggcc tgatcgccga ccgcacggcg gagttcgtcc ggctgcacgc cgagcggctg
     4441 gacgcgctgg ccgacccggc cgccgacgac cgcttcggct acttcgggct gcgcaccctg
     4501 cactcccgct acctgctgcg ccacccgctc acccgcaagg tgatcgagac cccgcagcac
     4561 ttcctgctgc gcgtcgccgc cggactcgcc gaggacgaca ccacccgggc gctggacgag
     4621 gtcgccgacc tgtacggcct gatgagccgc ctggactacc tgccctcctc ccccacgctc
     4681 ttcaactccg gcacccggca cccgcagatg tcgtcctgct atctgctgga ctccccgctg
     4741 gacgagctgg actcgatcta cgaccgctac caccaggtgg cccggctgtc gaagcacgcc
     4801 ggcggcatcg gtctgtcgta ctcccggatc cgctcccggg gttcgctgat ccgcggcacc
     4861 aacgggcact ccaacggcat cgtgccgttc ctgaagacgc tcgacgcgtc ggtggccgcc
     4921 gtgaaccagg gcggccggcg caagggcgcc gcggcggtct acctggagac ctggcactcc
     4981 gacatcgagg agttcctgga gctgcgggac aacaccggcg aggacgcccg ccgcacccac
     5041 aacctgaacc tcgcgcactg gatccccgac gagttcatgc gccgggtcga ggccgacggg
     5101 cagtggagcc tgttctcccc ggccgacgtg cccgagctgg tcgacctgtg gggcgaggag
     5161 ttcgacgcgg cctaccgcga ggccgagcgc aagggcctgg cgcggaagac cctgccggcg
     5221 cgcgagctgt acggccggat gatgcgcacc ctggcgcaga ccggcaacgg ctggatgacc
     5281 ttcaaggacg ccgccaaccg caccgccaac cagacggccg agccgggcca cgtcgtccac
     5341 tcctccaacc tctgcacgga gatcctggag gtcacgaacg acggcgagac cgcggtctgc
     5401 aacctgggct caatcaacct cggcgccttc gtggacggcc gggacatcga ctgggagcgg
     5461 ctggacgcca ccgtccgcac cgccgtcacc ttcctcgacc gggtcgtcga catcaacttc
     5521 tacccgaccg agcaggcggg ccgctccaac gcccgctggc ggccggtcgg cctcggcgcg
     5581 atgggcctgc aggacgtctt cttcaagctg cgcctgccct tcgactcccc cgaggcgaag
     5641 gccctgtcga cgcggatcgc cgagcggatc atgctggccg cgtacgaggc ctccgccgac
     5701 ctcgccgagc gcaacggccc gctcccggcc tgggagaaga cccgtaccgc gcgcggggtg
     5761 ctgcaccccg accactacga cgtcgaccgg acctggcccg agcggtgggc ggcgctgcgc
     5821 gagcggatcg cccgcgtcgg cctgcgcaac agcctgctgc tggccatcgc gccgacggcc
     5881 accatcgcct ccatcgcggg cgtctacgag tgcatcgagc cgcaggtgtc caacctgttc
     5941 aagcgcgaga cgctgtccgg ggagttcctc caggtcaact cctatctggt gcaggacctc
     6001 aaggagctgg gcgtgtggga cgcgcgcacc cgggaggcgc tgcgcgaggc gaacggctcg
     6061 gtgcaggact tcgcgtggat ccccgaggac gtgcgccggc tgtaccgcac ggcgtgggag
     6121 atcccgcagc gcggcctgat cgacatggcc gccgcccgca cgccgttcct ggaccagtcg
     6181 cagtcgctga acctgttcct ggagacgccg accatcggca agctctcctc gatgtacgcc
     6241 tacgcctgga agtccgggct gaagacgacg tactacctgc gctcgcgccc ggcgacccgc
     6301 atcgcccgcg ccgcgcgcgc cgccgtcccc gcgcagccgg ccgccgaccc cgaagcggtc
     6361 gcctgctccc ttgagaaccc cgagtcctgc gaggcctgcc agtgatgtcc ccccgtaacc
     6421 agaacctcct cgacccgggc ttcgagctga ccctgcgccc catgcgctac ccggacttct
     6481 acgagcgcta ccgggacgcc atcaagaaca cctggaccgt cgaggaggtc gacctccact
     6541 cggacgtcgc cgacctggcg aagctcacgc ccggcgagca gcacctcatc ggccggctgg
     6601 tggcgttctt cgcgacgggc gactcgatcg tcgcgaacaa cctggtgctg acgctgtaca
     6661 agcacatcaa ctcccccgag gcgcgcctgt acctctcgcg ccagctgttc gaggaggccg
     6721 tgcacgtcca gttctatctg acgctgctgg acacctacct ccccgacccg gaggagcggg
     6781 ccgcggcgtt cgcggcgatc gagaacatcc cgtcgatccg tgagaaggcg cagttctgct
     6841 tcaagtggat ggactcggtc gagaagatcg accggctgga gacccgggcc gagcggcgcc
     6901 gcttcctgct gaacctgatc tgcttcgccg cgtgcatcga gggcctgttc ttctacggcg
     6961 ccttcgcgta cgtctactgg ttccgcagcc ggggtctgct gcacggtctc gccaccggca
     7021 ccaactgggt gttccgtgac gagaccatgc acatgtcgtt cgcgttcgag gtcgtggaca
     7081 ccgtccgcaa ggaggagccg gacctgttcg acgaccggct ccagcaggag gtcaccgaca
     7141 tgctgcggga ggccgtggag gcggagctgc agttcgcgcg ggacctgtgc ggcgacgggc
     7201 tgccgggcat gaacaccgac tcgatgcggc agtacctgga gtgcgtcgcc gaccagcgcc
     7261 tgacgcgcct cggcttcgcc ccggtgtacg gctccgagaa cccgttcgcg ttcatggagc
     7321 tgcagggtgt tcaggaactg accaacttct tcgagcggcg tccctcggcg taccaggtgg
     7381 cggtggaggg cacggtcgac ctcgacgagg acttctgagc cggacgggtc cgtgcggcct
     7441 ccgccgcggc cagctgccgg tcgatccggc gctcgtggag ccagcccacg agcgccgggg
     7501 cggtgaggac gacggcgagg atcaggacgg tcgcgtagct gaagatcgtg ttcatgtagt
     7561 aagcgtcgta cttggtgaac actcatgaca gtggcaggac tgtcgtacac cctcgattta
     7621 ctgccaatgg cggtgcacac tggcagcatg ctgaagaacg tggccgccgt cctgctggac
     7681 ggtgtgcacc ccttcgaact gggtgtcgtc tgcgaggtct tcgggatcga ccgcagcgac
     7741 gagggactgc cgacgtacga cttcgcggtc gtctcggcgg agggctccgc gctgaccacg
     7801 cacgtcggcg ggctgacctt ggccacgccg tacggcctgg agcggctgga agaggctgat
     7861 ctgatcgctg tcccggcggg cgacgagtac gcgcgccggg agtacccgcc cgagctgctg
     7921 gacgccctgg tgcggggcgt ggagcgcggt gcgcgggtgc tcagcgtgtg ctccggggtc
     7981 ttcgtgctgg gcgcggccgg gctgctggag gggcggcgct gcgccgtgca ctggcaccac
     8041 gccggggagc tggcccggca gttcccgcgg gcggtcgtcg agcccgacgt gctgtacgtc
     8101 gacgaggacc cggtgatcac ctcggcgggc accgcggccg gcatcgacgc ctgtctgcac
     8161 ctggtgcgca aggagcaggg gccggaggtc gccaacaaga tcgcccggcg gatggtggtg
     8221 ccgccgcacc gggacggcgg gcaggcgcag tacatcgagc ggccgctgcc gaagagcacc
     8281 tgcgacaccg tcggcgaggt gctggcctgg atggagcagc acctcgacga ggaggtcacc
     8341 gtcgagcagc tcgccgcgcg ggcgcacatg tcgccgcgca ccttcgcccg ccgtttccag
     8401 caggagaccg gcaccacgcc ctaccgctgg atcctgcggc agcgcgtgct gctggcccag
     8461 gaactgctgg aggcgacgga cgagacggtc gacgcgatcg cctggcgcac cgggttcggt
     8521 acggcggcgg cgctgcggca ccagttcgtg cgcgcgctgg gcaccacgcc ccagagctac
     8581 cggcgcacgt tccgggggcc gcaggccgcc tgacctctcc cccgccgcta ccgtgccacc
     8641 ggcctgagca gcaggttctg cgggcgcagc gtgatcccga cgcgggtggt gtcgtcggag
     8701 gcggacacct gctcgaagcg gtacttcgtc gcgagcgccg ccgtgatcag ggtgagctgg
     8761 gccatggaga agtggtcgct ggggcacttg cggttgccga cgctgaaggg gctcatggcg
     8821 tacttgggga tgtccttgac gcgttccgga agccagcggt ccgggtcgaa ctccagattc
     8881 cggtcgtacg actccggatc gcgctggatc gcgtacggac tgtatacgat gtccgccccg
     8941 gccggaatgc gatagccacc gagttcggtg tcggtgaccg cccgccgcgt caatatccat
     9001 acggccggac gcaaacgcat ggcctcgacg acgacattgt tggtgtgccg gagcttgcgc
     9061 acgtcctcga atgcgaccgg ccggccgccg gtgacggatt cgacttcatc gcgcaccttg
     9121 tccgcgtgtt ccgggtgttc ggcaagtgcc tgaagcaacc acatgatcgt ggaagccacg
     9181 gtttcgctgc cgggggtgag gatcgcgacg acctggtcgt ggatctcctg ttcgtcgatg
     9241 gggtcgccgt tttcgtcctt cgcttgcagc aatgccgtca gcaaatcgtc cggcttttga
     9301 ccagatgccc gccgctcggc gacgatctcg tcgacgagga gatgcaaatc ggccagcgcc
     9361 cggttgaatt cgcggttcgc cggcagcggc agccggtaca gcgggccgag gggcaccacc
     9421 atccggcggt acataccgcg gaagacggtg gcgagggcgg tgcacaggcg ctcggcgcgc
     9481 tcgtccatgt agtcgccgcg cagcaggcag cgggcggcga tgcggacggc gacgcggaag
     9541 gactcggtgg tgcagtcgac ggtctcgccg ggcttccagc gctcggtgag ggcgtgcgcc
     9601 tcctcctcca tgatcggccc gtaggccggg atcgcgtcca gccggaacgc gggctggatg
     9661 gtgcgccgct ggcgccggtg ctgcggcccg ttggccgtgg ccacgccctt cttgccgagc
     9721 aggccctcca gcgactccca cagcggtccg gcgatgtggt actcggggct gagcgccagc
     9781 gcgccggtga gggccggggt ggtgacggcg tacaccgtct tcgggccgag tttgaggcgg
     9841 acgacctcgc cgtggtcgcg cagccgggac atgaaggcca gcgggtcgcg cagcagcggc
     9901 cagccgtggc cgaggagcgg gactcccccg ccggccaggg gcggctccag cagtcccgga
     9961 gccggggtgc cggtggtctc gggcttcacc tgctcgacgg tcatttctca cctgccgctt
    10021 cgttggtgac gtacgggggc gtggaccggt cctcccagct gtcgaccatg taccggccgg
    10081 attcgtggtg gaaccagtag acggaactga accagttccg catgttcgcg acgcaggcac
    10141 ggaccgcggc gccgagttct tttccgtgga ccgttccgtc ggcgagcgag tcggcgagcc
    10201 gcagggcttc ctgttccgcg acgaggaatt cggatatgca ttcctcgacg cgccgccgga
    10261 cctcttcgat tgcttcttcc agagtcagtc cgtgatgggt gatgagactg attccgagat
    10321 tgtgcacctc gtcgcccgcg atttccttgg gcagtgagca caggtcgttg taccaggcgg
    10381 cgaattcctg gctgaggagt gcggcccggc gataggccgg gtgtttccgc accccgtccg
    10441 ggagttcccg gcccgcggtc ggctccagca gatcggtcca gatccagtgg gcgaaggtga
    10501 ggcggcgcag ttccaggtat tcctcgaccg tgggcacgat tccctcggtc cggttgcgga
    10561 actcacggtc gtaggcgtcg atcaccgcgt ggaagtgccg ggtgaagcgg gcgttccagg
    10621 tgtccgacag gaaggcgaac agccgggcca cgctgtccgc cagacccgcg accagcgggt
    10681 ccgggtggtg cagatgggcc cccggggact ccagggccgc gtgcagtgcc tgccgcaggg
    10741 tgcgccaggc ggcggtcctg ccgtgcacga cgtaccggtc gtgccggtcg tcccagacga
    10801 agaaccaggt gctgtagtcg gcgatggcct gcagcacggc gtcgtcggcg ccgaggtagt
    10861 agcccgccat caggtcggtg tagcacaagc cgtcggcata ttcctcgacc ttgtccgccg
    10921 gcatcagccg tttttccagc agccagctcc gggtcttctc ctgaagcctt ggccaatacg
    10981 gatgcagttg ccggggaaac gccgcctcga tcaccggaag agcgagcgac ggcgggaccg
    11041 ccacccgggc cggcgccacc gtggtgccgt atgtggtgct gtatgggaaa gcatgcacga
    11101 actacccctc tcagccgcca gtgggcacac gccctcccgc tgtaccgggc gtgcgccgtt
    11161 gcgtatcccc gcacttccca ttcagcacca caactgaccg ttctgggaac ggatttgctt
    11221 cattcactac cccctgacgc cgagaatctc cccctatgtg gctggttgtg gatcaccaca
    11281 tgtgcgtagg gggtcgaacg cgcgacgagc aggcgaacgc ccccaagcag agcgcctgtt
    11341 caggtatgag gaacctgaac aggcgctggg cgtacgggcg ttgtgtgacg ggcggtgcgc
    11401 gtcagtcgtt ggccaccacc gggtagcgcg gctcgttctc ggccatctgg cgcagcgcgt
    11461 ccttgcgttc gcgcttggag agccggtcga tgtagaggta cccgtacagg tggtccgtct
    11521 cgtgctgcaa acaccgtgcg aagtagccgg tgccgcgcac cttgatcggg ttgccccgct
    11581 cgtcctgccc ggtcacctcg gcgtagtcgg gacgtgccag cggcatgtac gcggtcggca
    11641 cggacaggca gccctcgttg ctgtcgtcca ggcggcgctt gtcggcgggc agttcgacca
    11701 gcttggggtt gcagaccacg ccgacgtggc ggacgccgtt gtcgtcgggg cagtcgtaga
    11761 cgaagacctt caggtcgacg ccgatctggt tggcggccag gcccacgccc tcggcggtgc
    11821 gctgcgaggc gaacatgtcg tcgaccagct tgcgcagctc gtcgccgaac tcggtgacgt
    11881 ccttgcactc cttgtgcagc accgggttgc ccacgaccgt gatgggccgg gacgtgccgc
    11941 gctcgcggta cgcctgctcg cgctcctcgc agtcctcggt gtcgatgacg aaaccctcgt
    12001 cgtccacggg gagcacgccc gcgtgctgct gatcggtgtc ctgctgcgcc atgaccgacg
    12061 tacgccttcc tgcaagcctg gaaaattctg ccagtacagc ctaagtccgc gtgagcggtg
    12121 cgctcagcag acctcctcca gatcccgcca gtcccgtgag tccggggcgt cggccaccca
    12181 tccgtccagc aggccccgca ccagcgaggc cggcgcggcg accccgcact cccgctccgg
    12241 tacccacagc tgtccgtcgg tgcggtggcc cagcggtccc ggatgccccg gctcgctgtg
    12301 gtcgtgcggg tcgagatgga cgccgtcgcc ctcgtcggcc ggcatccgcg actccgagca
    12361 catccggcac agcagccgca ccgacgacga ccagtcctcc gcggcgaacc cggcgtccgc
    12421 ggcgagctgc tccagcgcgt cccggtcggc ctcggtggcc gcctcgatca gcaccaccca
    12481 ggtcggcacc ggcgacggcg cccacagctc gatctcgtcg aagacggggt aggagtgccc
    12541 ggcggaggtg gtccgctccc cgtgcggcac cccgtcgtgc agcacgacct cgccccagcg
    12601 ccgcccggac gacggcagcg ggatcgacag cacctcgatg cgggcggggt ccagccgccg
    12661 cccccacacc acctcggcct caccctcggg cgacagccgt acggccgcgc tgcccaggtc
    12721 catgccgacg ggctccccgg acgccgcggc acccgcgccg gcctgcgacc gagagccgcc
    12781 gccgggcacg cgcagcccgt aggcctgcca ggcccgccgg gccagcggcc agtcctgcag
    12841 ggccgtcgcc gcgatgccga cgttccacca gtcgggcgcc ccggtctcct tctccagcag
    12901 cgccaccgcg cgcagccccg ccgcccgcgc ctgttcccag tcgtgccgga acttgtgcag
    12961 cagcgcgagg ttgaaccacg actccgaccg ccagggctcc aggtcggcgg cgcgggtcag
    13021 cagcgctccc gcgtcctcgt accggccgtc gccgatcagc gtgaacgcgc ggtccgtggc
    13081 ctgccgccag gaggcggagg gccggtgccg tcccttgccg aagatcctca cgattcccgc
    13141 ctgccagttc cagttccgga aagtgggctg gcctgtgccc ccggacaccc tctccctcgc
    13201 atccaaccac gtacggctgg aggggcgctc attacccatg ggttacccag ccgcgggggc
    13261 agtcagactg ccccgggcca ggacgcgtgc cagtgcctcc accacctcgg gggcgtagtc
    13321 gcccgcggcg cccagccgca gctcctccag ggccgccagc gccccgccgg gaccggcgtc
    13381 gcgggccttc tcctcgtagg cgttgacgac ccggacgatc cgcgccgccc gcggctgctc
    13441 gggatagggg tcggcctgcc gctccaccac cgtcgcgacc tgcgggttca ccccggtctg
    13501 ccggaccacg gcaccgccga gcagggcgat cctgcgctgc tcggcgggcg gcagcgcggc
    13561 ggtggccccg gcgggcaccg ggtcgacgag gctcagctgg ccgatgtcgt gcatcagggc
    13621 cgcgtactcc agcacggtca gctccggctc ggtcagcccc aggtcccgtc cgaccgccag
    13681 gccgagcgcg gcgacccggt gggcgtgccc ggcgggggtg tacccggcga tctcggtggc
    13741 ccgggccagg gaggcgatgg tctgccggta ggtggcgcgg acggccgcgt accggcggaa
    13801 ggacagctgg gtgagcagca gcggcacaca gaacacgggc agcgcccaca ggcccgccgc
    13861 ggccaccgcg agcgccatca ccgcgccggt cgcgcacacg gccgagccga tcccggcgag
    13921 cgcccgcagc tcgtcccgca gcagcggccc gaacggccac cgggtgcggg cgtgcgccag
    13981 cgccgccgcg agcacggcgt cgcacagggc ggtgagcgtg agcagcgcca ccagcagcag
    14041 ggcgtaggcg ggaccgaccc aggagtcgaa gacgccccgg ttgtacagcg gctggaagca
    14101 gacggccgcg aagcccacgg tgaggacccg ccgggcgagg tggtccaggg tggggctctg
    14161 gccgcgcgcg atgtgcggca cgctgccgag cagcgaggcc gcgcacacga cggtgacgac
    14221 ctgggcggtc ccgtggtggg tgggccgccc ggccgcctcg ccgagcagcg cgtacgccag
    14281 cgccccggcg gcaccgagcg gggcggcctc ccgcagctgg gggccgcgcc agcgggtcag
    14341 ctcgccgacc gccacgagcg ctccgaaggc cagggcgagg gaccgctcca cagggccggt
    14401 ccgcagggtc accacgacgg agacggtgac gaggagaccg gcggccccgc gcacgacgac
    14461 gagcagcgcg ggcacgcccc ccagggacgc ggggaaccgc gcgaccggcc acgaccgcgc
    14521 cgcacccgcc cggctcacgg gcgcaccccc ggccgcccgt ggctcgcagc gtcccgtcgg
    14581 ggccggggca ccgccgcttc ctccgcggtc acggccggat gccacccctc cctggccagc
    14641 gcccgcgtca acgcctccac catgtccggg tcgaactgcg ccccggcgca ccgcctcagc
    14701 tcctccagcg cggtggccac cggccgggcc cgccggtagg aacgggtgga ggtcatcgcg
    14761 tcgaaggcgt cggcgacggc gaccacgcgg gcgcactcgg ggatctgcgc cccggacagc
    14821 ccgtaggggt agccgctgcc gtccaggcgt tcatggtggt gcaggatcgc cgcgcgggcc
    14881 tcgccgagga aggagatgcc gcgggtgatc tcatggccgt actccgggtg cagctcgatc
    14941 acgcgccgct cctcgggggt cagcggcccg tccttgcgca gcagccgagt gggcacgccg
    15001 agcttgccca cgtcgtgcag gatgcccgcg aggcgcagca cctcgacgcg ctcgtcgtcc
    15061 aggcccagct cgcgggcgat catcatcgag gcccggccga cgcgctcgct gtggccgcgc
    15121 gtgtacccgt ccttgatgtc gacggcctgc acgagcgccc ggatcgtggc ccggtgggcg
    15181 gcgcgctcgc ggtggtactg ggcgaacacc caccacgaga cgtacatcgg cagcagcacg
    15241 agcagcgcgg cgacgggccc gtaggggctg cgccacagga cggccatcat cagcccggcg
    15301 agcccgtgca ccgcgaccgg cgccagggag cgcccgaaca ccccgcggca ggtgcgcgcc
    15361 acgggggcgt ggtcggccag tgccaggaca cccgcgtcga ggacggcgag gaccaggcag
    15421 aacaccagca cggccgctcc ggcggggccg agcacgtagg ggaagtcggg ggtgacgacc
    15481 gcgtcccggc cgcccagcgc cccgtggacg cgggcggcgg cccacacggc gacgacgagc
    15541 tgggcggccc gccacacgcg ccgcagctgc acgctccggc gcacgccgtg ggacagcagt
    15601 gcccccggta ccgcgacgag cgccgcggcg ggcgggggca gcaggaaggc accggcgagg
    15661 aggacggggt agaacgttcc ggctaggcgc cggcgggcca actgctcgcc ggcggcgtag
    15721 agcgcggcca gcagcgcgac ggcccagccg ggcgaccgga cggagggcac gggcagcggc
    15781 agaggcagca ggagcgcgca ggcgcagacg gtgacaccgg cgacgtacac gcgtgcccgt
    15841 gccggaaccg cctccatgac gcaccatccc cctcgaccgt gccgtaccgg cttcggagcc
    15901 taggacggca cgggcggagt ccgcgggcgt atgacccgcg gattagcacg ttcgggtgac
    15961 ggcggtcccg gtcaggattc ctggggggtg gccgtgacgt cgtgctcggg gacggcctgc
    16021 ccggagcgga tcaggtcgat ccgccccatg accttggccc gcaggtcggt gggcacgtcg
    16081 tcatgcccgc agcaccgctt gaccagcttc ttcacggcct gctccagccc gtacttctcc
    16141 aggcaggggg agcactcctt gaagtgctgc tggaacttgt cgcgatcgac gtccggcatc
    16201 tcgctgtcga ggaactcgta caggtggtcg aggacctcac tgcagtccgt ctcgtgcggc
    16261 tctccgcagc tcatgagccc gagcctttcg cttcgttcga ctctccggcg ccggccggga
    16321 ccagcccgcg ctctcgggcg tagtcctcga gcatgccgcg cagttgccgg cggccccggt
    16381 gcagccggga catcaccgta ccgatgggtg tccccatgat gtccgcgatc tccttgtacg
    16441 caaagccctc cacgtccgcg aggtagacgg cgatgcggaa ctcctcgggg atcgcctgga
    16501 gcgcttcctt cacatccgag tcgggcaggt ggtcgagcgc ctgcgactcc gccgagcgca
    16561 gacccgtcga catgtgcgac tcggcgcgcg ccagctgcca gtcctcgatc tcctcggccg
    16621 cgctgcgctg gggttcgcgc tgcttcttgc ggtacgagtt gatgaaggtg ttggtcagga
    16681 tccggtacag ccacgccttg aggttggtgc cctcgcggaa ctggtggaag gacgcgtacg
    16741 ccttggcgta ggtctcctgg accaggtcct cggcgtcggc cgggttgcgc gtcatgcgca
    16801 gggcagccga gtacatctgg tcgaggaact ccagcgcgtc ccgctcgaag cgcgcgctgc
    16861 gctcggcggt cgactccgca cccgcgtccg cgctcacgcc cgggccctcg ggcagctccg
    16921 cctggccgtt gtcggtccct gcgtcggtac cgggaaccgg acccacctcc tccagcgatg
    16981 tcgtgagacc gagaccggtc ccactcgaat cggaggatag acgacgatcc ggcccgcccg
    17041 ccgcccgaat aggagcggtc ttggccgcgt gcagcaccgt ccagtccagg tcagcacggc
    17101 tgctgcggct cgggcagtag gtcgaaccca tgcggcggac ttcctctcca gtgacgtcgg
    17161 cgctggtggc cccagccctt ctgtccgcct caacagcggg tgcgcgccgg gcattcccgg
    17221 ccgttcaccc gagtgatccg gtccacttca cgacggcgtc ggtgatcacc gtcacggcct
    17281 cgtcctggcc gatcggcgcc cgtttcggca ccgcgaagcc atgatcgccg tacggcacct
    17341 cgaccagctc gtacgggccg tccgggaact cgtccggcct gccgaagggg tcgttgccgc
    17401 cctgcacgac gagcgtgggc accccggcgc cgagcagctc ctcggcgcgg gacttctccg
    17461 gtctgcccgg cgggtgcagc gggaagctca gcgcgagcac ggcgtgggcg cccagctccg
    17521 cggcggtacg gcaggccacg cgcgccccgg cgctgcgccc gccggcgatc accggcgggc
    17581 cgggccgggt gagcgcgggc cacaggccgc gccagccggt atcgagggtc ttcggcgcgg
    17641 gcgccacctt cttgccggcc acccgccagg gctgctcgac gagcgccacg gtcaccccgt
    17701 gcccgggcag cacgcgggcg agggcctgga ggtcacgggc ctcgatgccg ccgccggcgc
    17761 cgtggctgat ggccagcacc aaacgggcct tcctggccgt gtgccaggtg atgcgggccg
    17821 ggccggcctc ggtctcgacg gtctcctgtg tcgtgtgcgt cacgtcagaa gagtgtgccc
    17881 tcctccgggg cctccagctc cttgagcagc tccgggccgt tgttgcggac gttgctcacg
    17941 gccgtggaga ccgggtaggc ccgcatcagg ccgggcggcg ggggcgcgag cagctcccgc
    18001 aggtcgtcgg ggtcggtgcg ggccgggtcg agccaggcgt cccagcggtc cggggtgagc
    18061 atcagcggca tccgcgggtg gatgtcggcg agcgagtggg ggccctcggc gggggcgacg
    18121 gccagcggcg acgtctccgc ctcggtggtg atcaccgagc aggtcgccca ccaggcctgc
    18181 gggtggtcgt ccggcagcgt ccggtcccgc cagaactcgt acacaccggc catcgcgaac
    18241 accgacccgt cggccggcag cacgaagtac ggctgcttgc gcggccgctt cttgcggccc
    18301 tcgacctcca gctcgcgctc ctgcacgccg gtgacccact cgaagtagcc gtcggcgggg
    18361 aggatgcagc gccgggaggt gaaggcgcgg cggtaggacg gcttctcgtg cacggtctcg
    18421 gcccgcgcgt tgatcatccg cgcgccgccc tcgggcgtct tggcccagga cggcacgagc
    18481 ccccacttca gcttgcgcag ctgccgaacc gggcgcggct cggccgcgtc cttcaggggg
    18541 cggtccagga cggcgtacac ctccttggtc ggggccacgt tgtagtcggg cgccagggtc
    18601 tcctcgggct cccacttctc gatctcaaag attcctgcga gatcctctgg cctacgactc
    18661 gatgcatacc gtccgcacat acgtgccaca ctgccagact ccgccggaac acagggagca
    18721 gcccggaaac atggacacca gcacagcgac ctcgctctgg gacgaactcg tcggcaccca
    18781 gtccgagccg gacctgtggg tggtgatcgc gaccggtgtg gcggccctcg cggtggtcgt
    18841 cccgcaggcg gtgtggcgcg tcgcccgcaa cgccatcacc atcgcccacg agggcggcca
    18901 cggtctggtc gcgctgctca ccgggcgcca gctgaccggc atacggctgc actccgacac
    18961 cagcggtctc acggtcagcc gcggcaagcc gtacggactc ggcatgatcc tcaccgcggt
    19021 ggccggctac acggcgcctc cgctgctggg cctgggcggc gccgcgctgc tggccgcggg
    19081 acggatcacc ctgctgctgt ggctggcgac ggccctgctg ctggccatgc tcgtgatgat
    19141 ccgcaacgcg tacggcgccc tgacggtggt gctgacgggc accctgttcg tgctggtctc
    19201 ctggctgacg gggcctcagg tgcaggccgc gttcgcctac gcggtggtgt ggttcctgct
    19261 gctgggcggt gtacggccgg ccttcgagct gcaggccaag cgccggcacg ggggcgcggg
    19321 cgactcggac gccgaccagc tggcccggct gacgcacacc ccggcggggc tgtggctgtt
    19381 cctgttccac gcggtgtcgc tgtgctcgct gctgggcggg gggcgctggc tgctgggggt
    19441 gtgagcggcc ggcccggggg cgcggccgta cggctccacc gcgcggcccc ggccggcggt
    19501 ctcctcgcgg gcgccgcgga cgaacggcgg ccgtcgcctc cttataaagt ggccccatgg
    19561 tcccgaacgc cgcctccacc gccctctggc ccgccccgca cgcgagcgga gccgtcgacg
    19621 cgacggtcca cgtgcccggg tccaagtcgg tcaccaaccg cgccctcgtg ctcgccgccc
    19681 tcgcctccga gcccggctgg ctgcgccgcc cgctgcggtc ccgggacacg ctgctgatgg
    19741 ccggcgcgct gcgcgcgatg ggcatcgaga tcgaggaggg cgtgggcccc gacggcacgg
    19801 gcgaggcctg gcgggtgctg ccgacgggcc tgcgcggccc ggccaccgtg gacgtcggca
    19861 acgccggcac ggtgatgcgc ttcctgccgc cggtcgccac gctggccgac ggccccatcc
    19921 gcttcgacgg cgacccccgg tcctacgagc gtcccctgca cggcgtcatc gacgcgctgc
    19981 gcgccctcgg cgcccgcatc gacgacgacg gccgcggcgc gctgccgatg acggtgcacg
    20041 gcggcggcgc cctggacggc ggcgtggtcg agatcgacgc ttcctcgtcg tcccagttcg
    20101 tcagcgccct gctgctgtcc gcgccgcgct tcaaccaggg cgtggaggtg cggcacgtcg
    20161 gctccacgct gccgtcgatg ccgcacatcc ggatgacggt cgacatgctg cgcgcggtcg
    20221 gcgcccaggt ggacacgccc gagtcgggcg gcgagccgaa cgtctggcgg gtcacgccgg
    20281 gcgcgctgct cggccgcgac ctgacgatcg agccggacct gtccaacgcg cagccgttcc
    20341 tcgcggcggc gctggtgacc ggcggccggg tcgtcatccc ggactggccg gcccgcacga
    20401 cccagccggg tgaccggctg cgggagatct tcaccgagat gggtggttcc tgcgaactgg
    20461 ccgactacgg cctggtgttc accggttcgg gtgcgatcca cggtatcgat gtggacctga
    20521 gcgaggtcgg tgagctgacc ccgggcatcg cggcggtcgc ggccctcgcc gactccccct
    20581 ccacgctgcg gggcgtggcc catctgcggc tgcacgagac ggaccggctg gccgcgctca
    20641 ccaaggagat caacgagctg ggcggcgacg tcaccgagac cgccgacggc ctgcacatcc
    20701 gcccgcgccc gctgcacggc ggcgtcttcc acacgtacga ggaccaccgc atggcgacgg
    20761 ccggcgcggt catcggcctg gcggtcgagg gcgtgcggat cgagaacgtg gcgacgacgg
    20821 cgaagaccct gccggacttc cccgaactgt ggaccgggat gctcggggcg taggaacgca
    20881 gggacacgtc atgcgccgct atggcaagca caccgacgag gacgacatcc gcagccgccc
    20941 gggccgccgg ggcacccggc cccgtaccaa catccgtccc aagcacgagg acgccgccga
    21001 gggcatggtc ctcaccgtcg accggggccg gctcacctgc ctggtcgagg accgcacga
//
