LOCUS       NZ_BNBR01000003        21062 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces griseosporeus strain JCM 4766 sequence03, whole genome
            shotgun sequence.
ACCESSION   NZ_BNBR01000003
VERSION     NZ_BNBR01000003.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces griseosporeus
  ORGANISM  Streptomyces griseosporeus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 1004467)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 112X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014656055.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 05:04:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,365
            CDSs (total)                      :: 7,282
            Genes (coding)                    :: 7,186
            CDSs (with protein)               :: 7,186
            Genes (RNA)                       :: 83
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 96
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 96
            Pseudo Genes (frameshifted)       :: 41 of 96
            Pseudo Genes (incomplete)         :: 61 of 96
            Pseudo Genes (internal stop)      :: 11 of 96
            Pseudo Genes (multiple problems)  :: 15 of 96
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:46:46
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 513644
            Orig. end                         :: 534706
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BNBR01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21062
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21062
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21062
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11062](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11062)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(33..44)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            68..868
                     /locus_tag="IE308_RS17020"
                     /old_locus_tag="GCM10018783_34740"
     CDS             68..868
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006142339.1"
                     /locus_tag="IE308_RS17020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_34740"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_308440110.1"
                     /transl_table=11
                     /translation="MTDLVKDMAKSAGGHPMVRAEGVHKSFGLAHILKGIDLEVNPREV
                     FCLIGPSGSGKSTFLRCINHLEKISAGRLWVDGDLVGYRQKGDKLYELKEKEVAAQRRD
                     IGMVFQRFNLFPHMTALENVMEAPVQVKRESKAVARERAQRLLDRVGLGDRKGHYPAQL
                     SGGQQQRVAIARALAMEPKLMLFDEPTSALDPELVGEVLDVMRDLAESGMTMIVVTHEM
                     GFAREVGDSLVFMDGGVVVEAGHPREVLTNPQHERTKSFLSKVL"
     gene            949..2625
                     /gene="murJ"
                     /locus_tag="IE308_RS17025"
                     /old_locus_tag="GCM10018783_34750"
     CDS             949..2625
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0034204 - lipid translocation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="murJ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741660.1"
                     /locus_tag="IE308_RS17025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_34750"
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="WP_373314510.1"
                     /transl_table=11
                     /translation="MTTTPAPPNTHKPHGSSPEGGLLRSSALMAAGTVVSRITGFLRTL
                     VMATAIGVGTLNDTYQVANTLPTMIYVLVGGGALNSVFVPQLVRAMKEDPDGGEAYANR
                     LLTLVAVLMAAVTGVCVLGAPLLVHAMSPSIAADPHQQRVAVAFARYCLPTMFFMGVHV
                     VLGQILNARGRFGAMMWTPVLNNLVVIASFGAFVWVFGPFTRSHVDPAGVTPEGVRLLG
                     IGTLLGLTVQALAMVPYLRAAGFRIRPRLDWRGHGLGRAARLAKWTFLFVLANQAGMVV
                     VTQLATWAGSAAERQGHTGTGITAYNYALLLWQMPQAIVTVSVMTAVLPRISRAAQDGD
                     LAAVRADLSSGLRTSAVVVVPCAFAFLALGLPLATLLYSGTGQEGARGVGYVLMAFGLG
                     LIPYSAQYVVLRGFYAFEDTRTPFTNTVVVAAVNALASAACFWLLPARWAVAGMAASYG
                     LAFAVGVGVAWRRLRGRLGGDLDGARVRRTYAALCTASAVAAVAGGAVGAGLLGWLGSG
                     VPGSLAALAAGGAVFVGVFVAVARALRVAELRAVTGLLRRR"
     misc_feature    complement(2892..2907)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.99"
                     /tool="antismash"
     gene            2900..3529
                     /locus_tag="IE308_RS17030"
                     /old_locus_tag="GCM10018783_34760"
     CDS             2900..3529
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326935.1"
                     /locus_tag="IE308_RS17030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_34760"
                     /product="ABATE domain-containing protein"
                     /protein_id="WP_110630479.1"
                     /transl_table=11
                     /translation="MELAYYSDYAVRLVNSEEPARGTDTLTSVEAVRELFGANASAARR
                     ATDADVTRFRSVRARLRAVFQAADEGDETRAVDLLNALLLEFPVSPQISGHDHRDDDGR
                     PLWHMHLADHPSNATAGYAAIAAMGLAFHLTEYGVDRLGLCEATPCRNAYLDTSTNRSR
                     RYCSDRCATRANVAAYRARKRLEADRSAKTGLAAESAQRSTASGER"
     gene            complement(3433..3867)
                     /gene="sodX"
                     /locus_tag="IE308_RS17035"
                     /old_locus_tag="GCM10018783_34770"
     CDS             complement(3433..3867)
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016485 - protein processing [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009190575.1"
                     /locus_tag="IE308_RS17035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_34770"
                     /product="nickel-type superoxide dismutase maturation
                     protease"
                     /protein_id="WP_110637098.1"
                     /transl_table=11
                     /translation="MPELSQETERGRAVLPFGPAEVTGPSMVPTLYHGDRLLVRYGARI
                     RPGDVIVLRHPFQQDLLVVKRAVELREGGWWVLGDNAWAGGDSTDYGVVPEELVLGRVL
                     FRYRPARPGQRSPLAVLRWALSAARPVFADRSASRRLRAR"
     gene            4013..4408
                     /gene="sodN"
                     /locus_tag="IE308_RS17040"
                     /old_locus_tag="GCM10018783_34780"
     CDS             4013..4408
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016151 - nickel cation binding [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313646.1"
                     /locus_tag="IE308_RS17040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_34780"
                     /product="superoxide dismutase, Ni"
                     /protein_id="WP_110630477.1"
                     /transl_table=11
                     /translation="MLSRLFAPKVKVSAHCDLPCGVYDPAQARIEAESVKAVQEKMAAN
                     DDPHFQARATVIKEQRAELAKHHVSVLWSDYFKAPHFEKYPQLHQLVNDTLKALSAAKA
                     STDPKTGEKALELIAEIDKIFWETKKA"
     gene            4577..5116
                     /locus_tag="IE308_RS17045"
                     /old_locus_tag="GCM10018783_34790"
     CDS             4577..5116
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018524827.1"
                     /locus_tag="IE308_RS17045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_34790"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_190218598.1"
                     /transl_table=11
                     /translation="MADDRYGLVVDAGVEVPMPGDGETWAVGAVVLDGRGRAFAQRRGA
                     GRRLFPDCWDIVGGHVEAGESLLEALAREVREETGWRLRRVRRLLGVTSWTGDDGGGLR
                     HEADFLVDVDGDLDRPALEWSKHSAYDWFGPGDLDRLKENRSPGEYLVHDLIAAALGTG
                     SPAPTGLPDGRAILRE"
     gene            5164..5511
                     /locus_tag="IE308_RS17050"
                     /old_locus_tag="GCM10018783_34800"
     CDS             5164..5511
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010353600.1"
                     /locus_tag="IE308_RS17050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_34800"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_110637096.1"
                     /transl_table=11
                     /translation="MDREYAEPLDIAALARTALMSPGHFQRSFREAYGETPYGYLMTRR
                     VERAKTLLRRGDLTVTEVCIAVGCTSLGSFSSRFTELVGETPSAYRARSHAAGEQVPPC
                     VARTFTRPRRR"
     gene            5522..5938
                     /locus_tag="IE308_RS17055"
                     /old_locus_tag="GCM10018783_34810"
     CDS             5522..5938
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674926.1"
                     /locus_tag="IE308_RS17055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_34810"
                     /product="VOC family protein"
                     /protein_id="WP_190218599.1"
                     /transl_table=11
                     /translation="MDVKLKQCFIAVDDFDKALAFYVDVLGLEIRNDVAFEDMRWVTVG
                     SPLQPDVEIVLEPPAANPDFSPADREAMARLLAKGVLRGVNFTTADCDALYQRVQEAGG
                     DVLQEPMDQPYGVRDCAFRDPAGNMLRFMERRDG"
     misc_feature    complement(5546..5559)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.99"
                     /tool="antismash"
     gene            5972..6712
                     /locus_tag="IE308_RS17060"
                     /old_locus_tag="GCM10018783_34820"
     CDS             5972..6712
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019058264.1"
                     /locus_tag="IE308_RS17060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_34820"
                     /product="VOC family protein"
                     /protein_id="WP_190218600.1"
                     /transl_table=11
                     /translation="MTEPVLWTYAFADRPMDRFEAACAFWTAVTDTRLSELRGEHAEFT
                     TLLPAGADACVKVQGVAAGDGGAHLDLCVANVPGLVAAALRLGAQMLAEHDRWAVLRSP
                     GGQAFCAAPWQGERVRPPVTRGSRLDQVCLDLPPSVYAAEVAFWTALLPDWDSVPGSLP
                     EFHVVKPPPGLPMRILLQRLAEERPTGAHLDLACADIAATRARHETLGATALSHGSHWT
                     VMRDPAGGVYCLTGRDPETGGLPA"
     gene            complement(6709..7044)
                     /locus_tag="IE308_RS36955"
                     /old_locus_tag="GCM10018783_34830"
     CDS             complement(6709..7044)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657880.1"
                     /locus_tag="IE308_RS36955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_34830"
                     /product="DUF952 domain-containing protein"
                     /protein_id="WP_229908905.1"
                     /transl_table=11
                     /translation="MTEPILHLTEHSLWEAARAQGAYTMSTRGRTLDEEGFIHCSTRAQ
                     LPAVARFLYGSYDGPDELVVLVIDPERLDAPVRYEAPEPGAEAFPHVYGPIPVSAVVGT
                     EPWDQRA"
     misc_feature    7029..7043
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.99"
                     /tool="antismash"
     gene            complement(7054..8271)
                     /locus_tag="IE308_RS17065"
                     /old_locus_tag="GCM10018783_34840"
     CDS             complement(7054..8271)
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019072189.1"
                     /locus_tag="IE308_RS17065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_34840"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_229908906.1"
                     /transl_table=11
                     /translation="MDVPTPTEDLLRRCAPQVLGALVRRYGHFDAAEDAVQEALLAAAE
                     QWPRAGVPDNPRGWLIRVASRRLTDALRSDAARRAREERAAALGSRDVDGDGDRAPRED
                     DTLALLFLCCHPTLGRPAQIALTLRAVGGLTTAEIARAHLMPEAGMAQRISRAKKKVRG
                     VRFGRPDNWAERLPAVLHTLYLIFNEGYTATSGASLQRRDLAGEAIRLTRTVHHLLPDD
                     EEVAGLLALMLLTDARRDARSGPHGELIPLGEQDRDRWDRAAIREGVDLVTRALARRRP
                     GPYQLRAAIAAVHDEAPSEEETDWREILGLYDVLVRLVPGPVEQLNRIVAVAMVHGPRA
                     GLAALDGLDGDPGHRADAVRAHLLERAGDRTAARAAYERAAARTLSLPEQRYLRERAAR
                     LTRDKP"
     gene            complement(8281..8697)
                     /locus_tag="IE308_RS17070"
                     /old_locus_tag="GCM10018783_34850"
     CDS             complement(8281..8697)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007384635.1"
                     /locus_tag="IE308_RS17070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_34850"
                     /product="YciI family protein"
                     /protein_id="WP_190218601.1"
                     /transl_table=11
                     /translation="MKYLVMVQGTQAEYEGMAGKASETSPAWSEEEVQAVYAYMGALND
                     DLAETGEMIDGQGLAEPARTRLVTVDADGKPVITDGPYGETKEVLAGYWVLDCASLERV
                     TEIAEHVSRCPQPEGAARRAVVIRPIMDGSAGDC"
     gene            complement(9195..9788)
                     /locus_tag="IE308_RS17075"
                     /old_locus_tag="GCM10018783_34870"
     CDS             complement(9195..9788)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003998010.1"
                     /locus_tag="IE308_RS17075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_34870"
                     /product="N-acetyltransferase"
                     /protein_id="WP_190218602.1"
                     /transl_table=11
                     /translation="MGVAIRAAGEGDRELVIRLLDEAFQDDPVSSWVFPAADHRRRTHH
                     RLMAAFTDIVLAEGRVDLTEDGSACALWLSVPAGEHTDDDGPALLREAVDPANERVELI
                     GRLTAGIHPAHRAHEYLWMIGVAPGRQGEGLGSALLAHVLDRCDRDGVPAYLEASSARS
                     RALYARLGFATLTERVLDLPDGPRMWPMWREPRG"
     gene            complement(10001..11062)
                     /locus_tag="IE308_RS17080"
                     /old_locus_tag="GCM10018783_34880"
     CDS             complement(10001..11062)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973720.1"
                     /locus_tag="IE308_RS17080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_34880"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_229908941.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.3e-59, bitscore:
                     195.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPEARVTPEAPGDGAEAADILRRTRAVVDPELRAALETLPGPMR
                     RVALYHFGWQEADGRQASGGAGKALRPALVLAAAAALGGPAARGGAVRAAVAVELVHNF
                     TLLHDDVMDRDASRRHRPTAWTVFGDADAILAGDALLALALRLLAEDPHPASAAAAARL
                     ADCVVELCAGQHADTSLERRGPADVGLAEVLAMAEAKTGALIGCACAVGALYAGASARD
                     VEALDAFGREAGLAFQLIDDVIGIWGDPSRTGKPAGADLAARKKSLPVVAALASGTPAA
                     AELAALYETPYDKEDLNGTALAVERAGGRDWAQTEAADRMARAVQALSRAIPEPESAEG
                     LLALAEFVTRRST"
     gene            complement(11616..13022)
                     /locus_tag="IE308_RS17085"
                     /old_locus_tag="GCM10018783_34890"
     CDS             complement(11616..13022)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136651.1"
                     /locus_tag="IE308_RS17085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_34890"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_110630458.1"
                     /transl_table=11
                     /translation="MSVGEEVRTEQGRPQQSLGTAAARNLATTTKSVPQMQEISSRWLL
                     RMLPWVDVQGGTYRVNRRLTYAVGDGRITFVKTGDRVEVIPAELGELPAFRGYEDEDVL
                     AELARRCTQREVAAGEVIASFGSRTDEVYLLAHGRVEKVGTGPYGDDQVLGVLADGAYF
                     GDAALMSGDAIWEYTARADTACTLLVLSRDHVEQVAERAESLSGHLQQQRALPEQRTNK
                     YGEKEVELAAGHSGEPDIPHTFVDYEARPREYELSIAQTVLRIHSRVADLYNQPMNQTE
                     QQLRLTVEALKERQEHELVNNREFGLLHNCEYDQRIQPHDGVPGPDDMDELLSRRRGTK
                     MFLAHPRAIAAFGRELNKRGLVPETIDVGGNRIPTWRGVPIYPCNKIPVTPERTSSIIA
                     MRLGEADQGVVGLRQSGIPDEIEPSLSVRFMGINEQAIIKYLVTAYYSAAVLVPDALGV
                     LENVEIGRWR"
     gene            13330..13920
                     /locus_tag="IE308_RS17090"
                     /old_locus_tag="GCM10018783_34900"
     CDS             13330..13920
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006142330.1"
                     /locus_tag="IE308_RS17090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_34900"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_162655605.1"
                     /transl_table=11
                     /translation="MASPLSASAFLDALRDEGLTVVEVGDWRHHNRNHKGPWGPVHGVM
                     IHHTATEGAARTVELCRKGYTGLPGPLCHGVITKDGTVHLVGHGRANHAGLGDDDVLRA
                     VIAEKALPHDNEANTDGNRHFYGFECENLGDGQDPWPPAQLAAMEKAAAALCRRHGWTE
                     RSVIGHLEWQPGKVDPRGFTMAWLRERIRDRLK"
     gene            13943..14836
                     /locus_tag="IE308_RS17095"
                     /old_locus_tag="GCM10018783_34910"
     CDS             13943..14836
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019058274.1"
                     /locus_tag="IE308_RS17095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_34910"
                     /product="1-aminocyclopropane-1-carboxylate
                     deaminase/D-cysteine desulfhydrase"
                     /protein_id="WP_190218604.1"
                     /sec_met_domain="PALP (E-value: 1.4e-21, bitscore: 72.9,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGPDALRPRLPSPLQEVRDDRFDRRGVRLLLKREDLIHPELVGN
                     KWRKLAPNLTAAAGRTVVTFGGAWSNHLRATAAAGRLLGVPTVGVVRGDELAARPLNPS
                     LARCVADGMRLHFVDRSTYRRKAEPQTLAGLLRAAGAQGAYVVPEGGSNAHAVHGCVAL
                     GAELRGAADVVAVACGTGGTLAGLAAGLTPDQRALGVPVLRGGFLAEEVRRLQTEAFGG
                     PRGAWSLDDRFHGGGYARVPAELDAFAAAFEDRHGLPVERLYVAKLLYGLAALAEEGAF
                     PRGTTVAAVITGRPFP"
     gene            complement(14847..16445)
                     /locus_tag="IE308_RS17100"
                     /old_locus_tag="GCM10018783_34920"
     CDS             complement(14847..16445)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019072182.1"
                     /locus_tag="IE308_RS17100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_34920"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_190218605.1"
                     /transl_table=11
                     /translation="MDVMPLLLLVAGSAAIAAVARRTPVPAPLLLVAVGLAVSYLPGVP
                     DYTLEPDVVLPLLLPPLLYTSATDSSYLDLRAQTRPVALLSVGYVLFATVVVGLAAYAL
                     VPGLPLTAALVLGAVVAPPDAVAATAVARRVGLPSRITTILQGESLLNDATAITAYKVA
                     VAAAIGEGASWAGGIREFLIASVGGVAVGLVLMAPIHWLRTHLKEPLLQNTLSLLIPFV
                     AYAAAEQFHASGVLAVVVVALYLGHRAWEVDFATRLQEEAVWKMVAFVLESAVFALIGL
                     QLQFVLRGLGEYEGAEAAWYAVALFLVVVATRFLWVYPATFLPRLLSARIREREDNPTW
                     RGPVVIAWAGMRGVVSLAIAFSIPLTLHDGEEPFPHRNLVLFLTFTTVIGTLVVQGLTL
                     PPLIRLLKFPGRDTQAETLAEANAQAQASRAAEQRLDDLLSDERNTLPPPLADRLRTVL
                     ERRRNAVWERLGQVNPVTGETVDDTYRRLSREMISAEREVFVKLRDGRYIDDEMLRTLL
                     RRLDLEEAAAYRETA"
     gene            16507..16767
                     /locus_tag="IE308_RS17105"
                     /old_locus_tag="GCM10018783_34930"
     CDS             16507..16767
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571357.1"
                     /locus_tag="IE308_RS17105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_34930"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_110630452.1"
                     /transl_table=11
                     /translation="MKQCTHADALPHPEPAPLSETCPECLRDGTHPVQLRLCLTCGHVG
                     CCDSSPGRHATAHHADTGHPVMRTFEPGEDWRWCFVDHVLV"
     misc_feature    complement(16875..16888)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.89"
                     /tool="antismash"
     gene            17017..17430
                     /locus_tag="IE308_RS17110"
                     /old_locus_tag="GCM10018783_34940"
     CDS             17017..17430
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="IE308_RS17110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_34940"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_110630450.1"
                     /transl_table=11
                     /translation="MSHIDGEPVTQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGHAPSRDTFAWTV
                     LSALAGKVSSAVDEDKTVSISLYKQRGAGPGPA"
     gene            17427..18545
                     /locus_tag="IE308_RS17115"
                     /old_locus_tag="GCM10018783_34950"
     CDS             17427..18545
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030133.1"
                     /locus_tag="IE308_RS17115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_34950"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_190218606.1"
                     /transl_table=11
                     /translation="MRNGDGPVRDEERGTRELPPEDALGAQEGSRRMADGIDGIPEQAR
                     PHPVDDPAEAGVPDGGRRGHDGAAQSTPEDERIGVTPVRAPARARGRATGGTMSEHERN
                     GEHDAPGAQNAPGVRHDPQDRSGARALFVELRGLKEGSPEYAELRNRLVRMHLPLVEHL
                     ARRFRNRGEPLDDLTQVATIGLIKSVDRFDPDRGVEFSTYATPTVVGEIKRHFRDKGWA
                     VRVPRRLQELRLSLTTATAELSQQHGRSPTVHELAEKLAISEEEVLEGLESANAYSTLS
                     LDVPDTDDESPAVADTLGAEDEALEGVEYRESLKPLLEDLPPREKRILLLRFFGNMTQS
                     QIAQEVGISQMHVSRLLARTLAQLREKLLVEE"
     gene            complement(18584..19024)
                     /locus_tag="IE308_RS17120"
                     /old_locus_tag="GCM10018783_34960"
     CDS             complement(18584..19024)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983568.1"
                     /locus_tag="IE308_RS17120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_34960"
                     /product="hypothetical protein"
                     /protein_id="WP_110630447.1"
                     /transl_table=11
                     /translation="MSSEQTTSTEQPAGPRPRRLTYAAALAALEGLALVAGGVWMLVLG
                     LTGDPDDRQQAVTGGITLAVLALLPLLAARGLLARRSWSRGPAVITQIMALPVAYNLLT
                     SDGTGIPVGIVLAVVAVTSLVLLVNGETTRALGIRGPGGAQK"
     gene            19153..20121
                     /locus_tag="IE308_RS17125"
                     /old_locus_tag="GCM10018783_34970"
     CDS             19153..20121
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006134762.1"
                     /locus_tag="IE308_RS17125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_34970"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_190218607.1"
                     /transl_table=11
                     /translation="MRALLVVNPAATTTSARTRDVLIHALASEMKLEAVTTEYRGHARD
                     LGRQAALAEDIDLVVALGGDGTVNEVVNGLLHAGPDPERLPGLAVVPGGSTNVFARALG
                     LPNDAVEATGALLDALREGSERTVGLGLTSGTPGTEDAEVPQRWFTFNAGLGFDAGVVG
                     RVEQHRERGRKSTHALYVRQVVRQLLGEPNRRHGTITLERAGEEPVTELVLSIVSNTSP
                     WTFLGNRPIYASPKASFDTGLDVFGLSRLSTASVARYGTQLLTSSPERGPHGKHAVALH
                     DLDQFTLHSKVPLPLQMDGDHLGLRTSVTFTGVRRALRVIV"
     misc_feature    complement(20206..20220)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.74"
                     /tool="antismash"
     misc_feature    20207..20220
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.2"
                     /tool="antismash"
     misc_feature    complement(20211..20220)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     misc_feature    complement(20381..20396)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    20384..20395
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     gene            20441..20698
                     /locus_tag="IE308_RS17130"
                     /old_locus_tag="GCM10018783_34980"
     CDS             20441..20698
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563321.1"
                     /locus_tag="IE308_RS17130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_34980"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_003992873.1"
                     /transl_table=11
                     /translation="MDWRHNAVCREEDPELFFPIGNTGPALLQIEEAKAVCRRCPVIEQ
                     CLQWALESGQDSGVWGGLSEDERRAMKRRAARNRARQASA"
ORIGIN
        1 cgccgctgca gcgcctgcgc aggaacctcc gcgcgttcgg ttccttccgc cgcccggagg
       61 tggcccgatg accgacctcg tcaaggacat ggccaagagc gccggcggcc acccgatggt
      121 ccgcgccgag ggcgtgcaca agtccttcgg gctggcgcac atcctcaagg gcatcgacct
      181 ggaggtgaac ccgcgtgagg tgttctgcct gatcggcccg tccggttccg gcaagtccac
      241 cttcctgcgg tgcatcaacc acctggagaa gatcagcgcc ggccggctgt gggtcgacgg
      301 cgacctggtc ggctaccggc agaagggcga caagctctac gagctgaagg agaaggaggt
      361 cgcggcgcag cggcgggaca tcggcatggt gttccagcgc ttcaacctct tcccgcacat
      421 gacggctctg gagaacgtca tggaggcccc ggtccaggtc aagcgcgagt cgaaggccgt
      481 ggcacgggag cgcgcgcagc gcctgctgga ccgggtgggc ctcggcgacc gcaagggcca
      541 ctacccggcg cagctctccg gcggccagca gcagcgcgtc gcgatcgcgc gggcgctggc
      601 gatggagccg aagctgatgc tcttcgacga gccgacctcg gccctcgacc cggagctggt
      661 cggtgaggtc ctggacgtca tgcgcgacct cgccgagtcc ggcatgacga tgatcgtcgt
      721 gacgcacgag atgggcttcg cccgcgaggt cggcgacagc ctggtcttca tggacggcgg
      781 cgtggtggtc gaggccggcc acccgcgcga ggtgctgacc aacccgcagc acgagcgcac
      841 gaagtccttc ctgtcgaagg tcctctgagc agacgcacac cgtcagcggg gccgccccgg
      901 ggaaacccgg agcggccccg ctgccgtccg gtcgctaacc tcaccccggt gaccaccacc
      961 cccgcacccc cgaacaccca caagccgcac ggcagttcgc cggagggcgg gctgctgagg
     1021 tcctccgccc tcatggccgc cgggaccgtc gtctcccgga tcacggggtt cctgcgcacc
     1081 ctcgtgatgg ccacggccat cggggtcggc acgctcaacg acacctacca ggtcgccaac
     1141 accctgccga cgatgatcta cgtcctggtc ggcggcggcg cgctgaactc ggtgttcgtg
     1201 ccgcagctgg tgcgggcgat gaaggaggac ccggacggcg gcgaggccta cgccaaccgg
     1261 ctgctgacgc tggtggcggt gctgatggcg gccgtcacgg gcgtctgtgt gctgggcgcg
     1321 ccgctgctgg tgcacgcgat gtcgccgtcg atcgccgccg acccccacca gcagcgggtg
     1381 gcggtggcgt tcgcgcgcta ctgcctgccg acgatgttct tcatgggtgt ccatgtggtg
     1441 ctcgggcaga tcctcaacgc ccgcggccgg ttcggcgcga tgatgtggac gccggtcctg
     1501 aacaacctgg tggtcatcgc gtcgttcggc gccttcgtct gggtgttcgg cccgttcacg
     1561 cggtcccacg tcgaccccgc cggcgtcacc cccgagggcg tccggctgct cggtatcggc
     1621 acgctgctcg gcctcaccgt gcaagcgctc gcgatggtgc cgtatctgcg cgcggcgggc
     1681 ttccggatcc ggccgcggct ggactggcgc ggccacgggc tgggccgggc ggcccggctg
     1741 gccaagtgga ccttcctgtt cgtgctggcc aaccaggccg gcatggtcgt cgtcacccag
     1801 ctcgccacct gggcgggctc ggcggccgag cggcaggggc acacgggcac gggcatcacc
     1861 gcgtacaact acgccctgct gctgtggcag atgccccagg cgatcgtgac ggtgtcggtg
     1921 atgacggcgg tccttccgcg gatctcccgg gcggcgcagg acggggacct ggccgcggtc
     1981 cgcgccgatc tgtcctcggg gctgcgcacg tccgcggtgg tcgtggtgcc ctgcgccttc
     2041 gccttcctcg cgctgggcct gccgctggcg acgctgctgt actccggcac gggccaggag
     2101 ggcgcccgag gcgtcggcta cgtgctgatg gccttcgggc tcggtctgat cccgtactcg
     2161 gcgcagtacg tggtgctgcg cggcttctac gccttcgagg acacccggac gccgttcacc
     2221 aacacggtcg tcgtcgcggc ggtgaacgcg ctcgcctcgg cggcctgctt ctggttgctg
     2281 cccgcccgct gggcggtggc cgggatggcc gcgtcgtacg gcctggcgtt cgcggtcggt
     2341 gtcggggtgg cctggcggcg gctgcgcggg cggctcggcg gcgatctgga cggggcccgg
     2401 gtccgccgca catacgccgc cctgtgcacg gcgtcggcgg tcgcggcggt ggccggcggg
     2461 gcggtcgggg cggggctgct ggggtggctc ggcagcgggg tgccggggtc gctcgcggcg
     2521 ctggccgcgg gcggggccgt cttcgtcggt gtgttcgtcg ccgtggcccg ggcgctgcgg
     2581 gtggcggagc tgcgggcggt caccgggctg ctccgccgtc gctgacgtgc gccgagtcgc
     2641 gggccggtgg ctacctgagc gccggcagca gggtgtccga gggcgaggtc cacacgtccg
     2701 ggtcggtgag atcggcctcg acgaagccga cgcggtcgtc gccggcgatg gtgagcaggg
     2761 cggggtcgag gtcgaggacg cgcggttcgg aaccgacgaa ggccccccgt cacagctcac
     2821 acgtaatacc ctttaggtac gaccggctgt taccgaccgc acgcacgacg acgatagcgc
     2881 gcgcccgtaa ggactacaag tggaactggc ctattactcg gactacgccg tacggctcgt
     2941 gaacagcgag gaaccggccc ggggcacgga caccctgacc tcggtcgagg ccgtccgcga
     3001 gctgttcggc gccaacgcct cggcggcccg ccgcgccacc gacgcggacg tgacccggtt
     3061 ccgctcggta cgggcccggc tgcgcgcggt gttccaggcc gccgacgaag gcgacgagac
     3121 ccgcgcggtg gacctgctca acgccctgct gctggagttc ccggtcagcc cccagatctc
     3181 cgggcacgac caccgggacg acgacggccg ccccctgtgg cacatgcacc tggccgacca
     3241 cccgtcgaac gcgaccgcgg gctacgcggc catcgcggcg atgggcctcg ccttccacct
     3301 caccgagtac ggcgtggacc ggctcggcct gtgcgaggcg acgccgtgcc gcaacgccta
     3361 cctcgacacc tccaccaacc gctcccggcg ctactgctcc gaccgctgcg ccacccgcgc
     3421 caacgtggcc gcctaccgcg cccgcaagcg cctggaggcc gaccggtcgg cgaagacggg
     3481 cctggccgcg gagagcgccc agcgcagcac ggccagcggg gagcgctgac cgggccgggc
     3541 cggccggtag cggaacagga cccggccgag gaccagttcc tcgggtacga cgccgtagtc
     3601 ggtgctgtcg ccgccggccc aggcgttgtc gcccagcacc caccagccgc cctcgcgcag
     3661 ctcgacggcc cgcttgacga cgagcaggtc ctgctggaag gggtggcgca ggacgatgac
     3721 gtcgccgggc ctgatccggg cgccgtaccg caccagcagc cggtcgccgt ggtacagcgt
     3781 gggcaccatc gacggccccg tcacctcggc cggcccgaag ggcagtacgg ccctgccccg
     3841 ctcggtctcc tgcgacagct ccggcatccc cggcacctcc ccggtccgtt cctccaccag
     3901 tctcagtctg accctggact tttgtcctaa gcccatgggg gcactcgcga aaacccgtcc
     3961 cgcagggagt aatgtcccac ctgagaagac gatcacgagg aaggaatgct ccatgctttc
     4021 ccgcctgttt gcccccaagg tcaaggtcag cgcgcactgc gacctgccct gcggtgtgta
     4081 cgacccggcc caggcccgca tcgaggcgga gtcggtgaag gccgtccagg agaagatggc
     4141 cgccaacgac gacccgcact tccaggctcg tgccacggtc atcaaggagc agcgcgccga
     4201 gctggcgaag caccacgtct ccgtgctctg gagcgactac ttcaaggccc cgcacttcga
     4261 gaagtacccg cagctgcacc agctggtcaa cgacaccctg aaggccctgt cggccgccaa
     4321 ggcctccacg gaccccaaga cgggtgagaa ggccctggag ctcatcgccg agatcgacaa
     4381 gatcttctgg gagaccaaga aggcctgacc ttcgctccca cggcccgacc tgcgatcggt
     4441 gcaccatcgc gagtcgaccg gacggaaaag gggccccgcc gcaacccggc ggggcccctt
     4501 ttccatgccc gggcgcaacc cggcgggccc ccttttccgc gcccggccac ccgcgcacgg
     4561 cccctacagt gaccccatgg cagacgatcg gtacggcctc gtcgtggacg ccggtgtcga
     4621 ggtgcccatg cccggggacg gcgagacgtg ggcggtgggg gcggtcgtgc tcgacgggcg
     4681 ggggcgggcg ttcgcgcagc ggcgcggcgc cggccggcgg ctgttccccg actgctggga
     4741 catcgtcggc gggcatgtgg aggccggcga gtccctgctg gaggcgctcg cccgggaggt
     4801 gcgggaggag accggctggc ggctgcgccg ggtgcggcgg ctgctcgggg tcacctcatg
     4861 gaccggcgac gacggcggcg ggctgcggca cgaggccgac ttcctggtgg acgtcgacgg
     4921 cgacctggac cgccccgcgc tggagtggtc caagcactcc gcctacgact ggttcgggcc
     4981 cggcgatctg gaccggctca aggagaaccg gtcgcccggc gagtacctgg tccacgacct
     5041 gatcgccgcg gcgctcggca ccggctcccc ggccccgacc ggtctgccgg acgggcgtgc
     5101 catcctgagg gagtgacgac caccacggag gacctggtcc ggctgcggcg ggcccgtgac
     5161 cggatggacc gcgagtacgc cgagccgctg gacatcgccg cgctcgcccg taccgcgctg
     5221 atgtcccccg gccacttcca gcgcagcttc cgcgaggcct acggcgagac gccctacggc
     5281 tacctcatga cccgccgcgt cgagcgtgcc aagacgctgc tgcggcgcgg cgacctgacg
     5341 gtgacggagg tgtgcatcgc ggtcggctgc acctcgctcg gctcgttcag ctcgcgcttc
     5401 acggagctgg tcggggagac gccgagcgcg taccgggcgc gctcgcacgc ggcgggcgag
     5461 caggtcccgc cctgcgtggc gcgcaccttc acccgcccgc gccgccgtta ggttcaccgc
     5521 catggacgtg aaactgaagc agtgcttcat cgccgtcgac gacttcgaca aggcgctcgc
     5581 cttctacgtg gacgtgctcg gcctggagat ccgcaacgac gtggccttcg aggacatgcg
     5641 ctgggtgacc gtggggtcgc cgctccagcc ggacgtggag atcgtgctgg agccgcccgc
     5701 cgccaacccg gacttctccc ccgccgaccg tgaggcgatg gcccggctgc tggccaaggg
     5761 cgtgctgcgc ggggtgaact tcaccaccgc ggactgcgac gccctctacc agcgcgtcca
     5821 ggaggccggc ggggacgtgc tgcaggagcc gatggaccag ccgtacggcg tgcgggactg
     5881 cgcgttccgg gacccggcgg ggaacatgct gcggttcatg gagcgccggg acggctgacc
     5941 gcgccgaacg gcccgccgta cgatcgcccg catgaccgaa cctgtgctgt ggacctacgc
     6001 gttcgccgac cgcccgatgg accgcttcga agcggcctgc gccttctgga cggccgtcac
     6061 ggacacccgt ctgtccgagc tgcgcggtga acacgcggag ttcaccaccc tgctgcccgc
     6121 cggggcggac gcctgcgtga aggtgcaggg ggtcgcggcg ggcgacggcg gcgcgcatct
     6181 cgacctgtgc gtggcgaacg tgcccggcct ggtcgcggcg gccctgcggc tcggcgcgca
     6241 gatgctcgcc gagcacgaca ggtgggcggt actgcggtcg ccgggcggac aggcgttctg
     6301 cgcggcgccc tggcaggggg agagggtacg gccgcccgtg acgcgcggca gccgcctgga
     6361 ccaggtgtgc ctggacctgc cgccgtcggt gtacgccgcc gaagtcgcct tctggaccgc
     6421 gctgttgccg gactgggact cggtgcccgg ctcgctcccc gagttccacg tggtcaagcc
     6481 gccgcccggg ctgcctatgc gcatcctcct gcagcgcctg gcggaggaac ggccgacggg
     6541 cgcccatctc gacctggcct gcgccgacat cgccgcgacc cgcgcccgcc acgagacgct
     6601 gggcgcgacc gcgctctccc acggctccca ctggacggtc atgcgcgacc cggccggcgg
     6661 ggtgtactgc ctgacgggac gggacccgga gacgggcggc ctgcccgcct aggcccgctg
     6721 gtcccagggt tccgtgccga cgaccgccga caccgggatc gggccgtaga cgtgcgggaa
     6781 cgcctcggcg ccgggctccg gtgcctcgta cctcaccggc gcgtccagcc gctccgggtc
     6841 gatgaccagg accaccagct cgtcggggcc gtcgtaggag ccgtagagga agcgcgccac
     6901 ggccgggagc tgggcgcggg tcgagcagtg gatgaagccc tcctcgtcga gggtgcggcc
     6961 ccgggtggac atcgtgtagg cgccctgcgc gcgggccgct tcccacaggg agtgttcggt
     7021 gaggtgcagg atgggttcgg tcatgcgggc accctagggc ttgtcgcggg tgaggcgtgc
     7081 ggcgcgctcg cgcagatagc gctgctcggg gaggctcagg gtgcgggcgg cggcccgttc
     7141 gtaggcggcg cgggcggcgg tgcggtcgcc ggcgcgttcc agcaggtggg cgcggacggc
     7201 gtccgcgcgg tggcccgggt cgccgtccag cccgtccagt gcggccagcc ccgcgcgcgg
     7261 gccgtgcacc atggcgacgg cgacgatccg gttgagctgc tcgacggggc cggggacgag
     7321 acggacgagg acgtcgtaga ggccgaggat ctcccgccag tcggtctcct cctccgaggg
     7381 tgcctcgtcg tgcacggcgg cgatggcggc gcgcagctgg taggggccgg gccggcgccg
     7441 ggcgagcgcg cgtgtcacca ggtcgacgcc ctcacggatc gcggcgcggt cccagcggtc
     7501 gcggtcctgt tcgccgagcg ggatcagctc cccgtgcggc ccgctgcgcg cgtcccggcg
     7561 ggcgtcggtc agcagcatca gcgcgagcag cccggccacc tcctcgtcgt cgggcagcag
     7621 gtggtgcacg gtgcgggtca gccggatcgc ctcgccggcc aggtcgcgcc gctggagact
     7681 cgcgcccgag gtggccgtgt acccctcgtt gaagatcagg tagagggtgt gcaggacggc
     7741 cgggagccgt tcggcccagt tgtcgggccg cccgaagcgc acgccccgca ccttcttctt
     7801 ggcccggctg atccgctgcg ccatccccgc ctcgggcatg aggtgggcgc gggcgatctc
     7861 cgccgtggtc aggccgccga ccgcgcgcag ggtgagcgcg atctgcgcgg gccggccgag
     7921 cgtgggatgg cagcacagga agagcagcgc gagcgtgtcg tcctcacgcg gggccctgtc
     7981 cccgtccccg tccacgtccc gcgagccgag cgccgccgcc cgctcctccc gggcccggcg
     8041 cgccgcgtcg ctgcgcagcg cgtcggtcag ccgccgcgag gccaccctga tcagccagcc
     8101 ccgcgggttg tccggcaccc cggcccgcgg ccactgctcc gccgccgcga gcagcgcctc
     8161 ctgtacggcg tcctcggcgg cgtcgaagtg cccgtaccgc cggaccagcg cgccgaggac
     8221 ctgcggcgcg caccggcgca gcaggtcctc ggtgggggtg gggacgtcca tcgggcacgc
     8281 tcagcagtcc ccggcgctcc cgtccatgat cggccggatc acgaccgccc tgcgggccgc
     8341 gccctccggc tgggggcagc ggctgacgtg ctcggcgatc tcggtgaccc gctccaggct
     8401 cgcgcagtcc agcacccagt acccggcgag gacctccttc gtctcgccgt acggcccgtc
     8461 ggtgatcacg ggcttgccgt ccgcgtccac ggtgaccagg cgggtccgcg ccggctcggc
     8521 gaggccctgc ccgtcgatca tctcgccggt ctcggcgagg tcgtcgttga gggcgcccat
     8581 gtaggcgtac acggcctgga cctcctcctc gctccaggcc ggtgacgtct cggaggcctt
     8641 gccggccatg ccctcgtact ccgcctgcgt gccctgcacc atgaccaggt acttcatcgg
     8701 tccgctcctt gtgcgttcgt cggcctcggt cggctttcac aggggacgtc ggagccggtc
     8761 cgcgattctc gacacggtgg tcaggaattc tcgggtcagg aattctcggg accgggggcg
     8821 ggggcggtac cgggggcggg ggcggcgtca gtgcccgtgc ctgcgctcgt gcctgcgcct
     8881 gtgcctgtgc ccgtgctcgt gcccgtgccg ccgtcctcgc gggccggctc cggcgcacgg
     8941 ggctccccag gaggcgctgc ggacttgttc ccgaccgcgc tccccgcccg gccgtgctcc
     9001 tcggcggccg gtgtgccgta cgccgcgcag ccggggttgc ggcagggccc cggcgcccac
     9061 accggcaccc acgcgcccag cgtcttgtgg cgccggacga ccgtctcgac aggctgtccg
     9121 cagacgggac agacgtgttc ctcgcggtcc attccctcag cgtagggcgg cccggcctcc
     9181 ggcgcccctc gccgtcagcc gcgcggctcg cgccacatgg gccacatgcg ggggccgtcc
     9241 ggcaggtcga ggacgcgctc ggtgagggtg gcgaacccga ggcgggcgta cagggcgcgg
     9301 ctgcgggcgc tgctcgcctc caggtaggcg ggcacaccgt cgcggtcgca gcggtcgagg
     9361 acgtgcgcga ggagggcgct gccgaggccc tcgccctggc ggccgggggc gacgccgatc
     9421 atccacaggt actcgtgggc gcggtgcgcg gggtggatcc ccgcggtgag ccggccgatc
     9481 agctcgacgc gttcgttggc cgggtcgacg gcctcacgca gcagggcggg gccgtcgtcg
     9541 tcggtgtgct ccccggccgg gacggacagc cacagggcgc aggcggaacc gtcctccgtg
     9601 aggtcgacgc ggccctcggc gagcacgatg tcggtgaagg ccgccatcag ccggtggtgg
     9661 gtcctgcggc ggtggtcggc cgcaggaaac acccaggagc tgaccggatc gtcctggaag
     9721 gcctcgtcca gcagccggat caccagctcc cggtcgccct cccccgcagc ccggatcgcc
     9781 acgcccatgt ccacccctcc gcctcaaccg ccgtttccgc caaggaggtt gagcctatcc
     9841 agggcccggt acgggggcat gtccggggcc ccgtgcgggg agggcgggcc ccgcgcaccg
     9901 tggggttgcg cggggcccct ccggccggca ccgccgggga ccgtgcgggg tcaggaaccg
     9961 cacggtcgcc ggcggcccgg ggtccggtgg cgggcggcgg tcaggtgctg cgccgggtga
    10021 cgaactcggc cagcgcgagc agcccttcgg ccgactccgg ctccgggatc gcgcgggaca
    10081 gtgcctgcac cgcgcgggcc atccggtcgg cggcctcggt ctgcgcccag tcccgcccgc
    10141 cggcccgctc cacggcgagt gccgtgccgt tcaggtcctc cttgtcgtac ggcgtctcgt
    10201 acagcgcggc cagctccgcc gccgccgggg tgccggaggc gagcgccgcg accaccggca
    10261 gggacttctt gcgggcggcg aggtccgcgc cggccggttt gccggtgcgg ctgggatcgc
    10321 cccagatgcc gatgacgtcg tcgatgagct ggaaggcgag cccggcctcc cggccgaacg
    10381 cgtccagcgc ctcgacgtcc cgcgcggacg ctcccgcgta cagcgccccc accgcgcagg
    10441 cgcagccgat cagcgcgccg gtcttggcct cggccatggc gagcacctcc gccaggccca
    10501 cgtcggcggg gccgcgccgc tccagcgagg tgtccgcgtg ctgcccggcg cacagttcga
    10561 cgacgcagtc cgcgagccgg gccgccgcgg cggcggaggc cgggtgcggg tcctcggcga
    10621 gcagccgcag ggcgagcgcc aggagggcgt ccccggcgag gatcgcgtcg gcgtcgccga
    10681 acacggtcca ggcggtgggc cggtgccggc ggctggcgtc ccggtccatc acgtcgtcgt
    10741 ggagcagggt gaagttgtgg accagttcca ccgcgacggc ggcccgtacg gcgccgcccc
    10801 gggccgcggg gccgccgagc gcggcggctg ccgcgaggac gagcgcgggc cgcagggcct
    10861 tgcccgcgcc gccggaggcc tgtctgccgt ccgcctcctg ccagccgaag tggtagagcg
    10921 cgacacggcg catggggccc ggcagggtct ccagggccgc acgcaactcg gggtcgacca
    10981 cggcacgggt gcgccgcagg atgtcggctg cctcggcacc gtcacccggg gcttccgggg
    11041 tgacccgggc ctctggtgcc accggcgctt ccgggacagc gggaggcacg gccggtgtcg
    11101 tcggggtggc cgggggtacg gccggtgccc tcggagtggc cgggggtacg gccggttccc
    11161 tcggagtggc cgggggcacg gccggtgccg tcggggcggc cgggagtacg gccggttccc
    11221 tcggagtggc cgggggtacg tccggtgcga ccaggccgcc tgcacgtgcg gccggggtgt
    11281 ccggagccgc ggcggccgaa ggcacggccg gcccggccgg ggctgacgga cgtgccgccg
    11341 gtaccacccg agccgtcggt accgccgggg cgggcgccgc ggccggggtg ccggcatccc
    11401 cccggcgcgc gcgctgaccg ctgatcccgg gcggtcccgg ccgtggcgtg gtgcggacgc
    11461 cgcccgggct gtcggcgggc tgggtcaggg actcggtcaa cggctccccc tcggcaggtc
    11521 ggcggacggc ggccgtgccg ccggggtccg gccggtgccc ccgcggtgcc cccgcccggg
    11581 cgggcgggcg cacggcgtcc cggcggcggg gacggtcatc gccagcggcc gatctcgacg
    11641 ttctccagca cgccgagggc atcggggacg aggacggcgg ccgagtagta ggccgtcacg
    11701 aggtacttga tgatggcctg ttcgttgatg cccatgaacc gcacggacag gctcggctcg
    11761 atctcgtcgg ggatgccgga ctggcgcagg cccacgacgc cctggtcggc ctcgccgaga
    11821 cgcatcgcga tgatggagct ggtgcgctcg ggtgtgaccg ggatcttgtt gcacgggtag
    11881 atcggcacgc cccgccaggt ggggatgcgg ttgccgccga cgtcgatggt ctcgggcacc
    11941 agtccgcgct tgttgagttc gcggccgaac gcggcgatcg cgcgcgggtg ggcgaggaac
    12001 atcttggtgc cgcgccgccg gctgagcagc tcgtccatgt cgtccgggcc gggcacgccg
    12061 tcgtgcggct ggatccgctg gtcgtactcg cagttgtgga gcaggccgaa ctcgcggttg
    12121 ttgaccagct cgtgctcctg gcgctccttc agcgcctcga ccgtgagccg cagctgctgc
    12181 tcggtctggt tcatcggctg gttgtacagg tcggccacgc gcgagtggat gcgcagcacg
    12241 gtctgggcga tgctcagttc gtactcgcgg ggccgggcct cgtagtcgac gaaggtgtgc
    12301 gggatgtccg gctcgccgga gtggccggcg gcgagttcga cctccttctc gccgtacttg
    12361 ttggtgcgct gctccggaag ggcgcgctgc tgctgcaggt ggccgctgag ggactcggcg
    12421 cgctcggcga cctgctcgac gtggtcgcgg ctgaggacga gcagggtgca cgccgtgtcc
    12481 gcgcgggcgg tgtactccca gatggcgtcc ccgctcatca gcgccgcgtc gccgaagtag
    12541 gcgccgtcgg cgagcacgcc gagcacctgg tcgtcgccgt aggggccggt gccgaccttc
    12601 tcgacgcggc cgtgcgccag caggtagacc tcgtcggtgc ggctgccgaa ggaggcgatg
    12661 acctcgcccg cggcgacctc gcgctgggtg cagcgccggg cgagttcggc cagcacgtcc
    12721 tcgtcctcgt accccctgaa cgcgggcagt tcgcccagct cggcggggat gacctcgacg
    12781 cggtcgccgg tcttcacgaa cgtgatgcgg ccgtcgccga cggcgtacgt caggcgtcgg
    12841 ttgacgcggt atgtgccgcc ctgcacgtcc acccacggaa gcatccgcag cagccagcgc
    12901 gagctgatct cctgcatctg cggaacggac ttggtggtgg tggccaggtt ccgcgcggcc
    12961 gcggtgccga ggctctgctg cggcctgccc tgctcggtgc ggacctcttc gcctaccgac
    13021 ataaggaatt gccctcccgg tcatgctccg gcatccgaac tgcgccgggc attcgatctc
    13081 gtgaccaggg tttcatcacg caccgtgccg gtgctattac acgaaagagc ggggttggaa
    13141 ccccgcacgg tgggcacaaa tgggggctct gtccagcggt cggcggctcc gccggttgtc
    13201 cggatcggct cgcacactgt gcgaagcagg tggtccggat cgttccgttt cggtagaagg
    13261 tccgttacga aagacggccg cgttctgcgg ccgtggacag cagcacgacg gaacgccgag
    13321 gaggcagtca tggcctcgcc cctgtccgca agcgcattcc tggacgccct cagagacgag
    13381 ggcctgaccg ttgtcgaggt cggcgactgg cgccatcaca accgcaatca caagggcccg
    13441 tgggggcccg tgcacggcgt gatgatccat cacacggcga ccgagggtgc cgcccggacc
    13501 gtcgagctgt gccgcaaggg ctacaccggt ctgccgggcc cgctgtgcca cggcgtcatc
    13561 accaaggacg gcaccgtcca cctcgtcggc cacggccgcg ccaaccacgc cggtctcggc
    13621 gacgacgacg tgctgcgcgc ggtgatcgcg gagaaggcgc tgccgcacga caacgaggcg
    13681 aacaccgacg gcaaccggca cttctacggc ttcgagtgcg agaacctcgg cgacggccag
    13741 gacccctggc cgcccgccca gctggcggcg atggagaagg ccgcggcggc gctgtgccgg
    13801 cggcacggct ggaccgagcg gtcggtgatc ggccacctgg agtggcagcc ggggaaggtg
    13861 gatccgcggg ggttcacgat ggcgtggctg cgggagcgga tccgggaccg cctgaagtga
    13921 gcgcctgttc gacaatgggg cggtgaccgg tcccgacgcc ctgcggcccc gcctgccctc
    13981 cccgcttcag gaggtgcggg acgaccgttt cgaccggcgc ggtgtgcgcc tgctgctgaa
    14041 gcgggaagac ctgatccacc cggagctggt cggcaacaag tggcgcaagc tggccccgaa
    14101 cctcacggcc gcggccggcc gtacggtcgt caccttcggc ggggcctggt cgaaccatct
    14161 gcgggccacc gccgccgcgg gccggctgct cggcgtgccg acggtgggcg tggtgcgcgg
    14221 cgacgaactg gccgcgcgcc cgctcaatcc ctcgctggcc cggtgcgtgg ccgacggcat
    14281 gcggctgcac ttcgtcgaca gatcgacgta tcgccgcaag gcggagccgc agacgctggc
    14341 cgggctgctg cgcgcggccg gtgcgcaggg ggcgtacgtc gtcccggagg gcggcagcaa
    14401 cgcgcacgcc gtccacggct gcgtggccct cggcgccgag ctgcgcgggg ccgcggacgt
    14461 cgtcgccgtg gcctgcggca ccggcggcac gctcgcgggc ctggccgccg gcctcacccc
    14521 ggaccagcgc gccctcggcg tccccgtcct gaggggcggc ttcctcgcgg aggaggtgcg
    14581 gcggctccag acggaggcct tcggcgggcc gcgcggcgcc tggtcgctgg acgaccgctt
    14641 ccacggcggc ggctacgcgc gcgtaccggc cgagctggac gccttcgcag cggcgttcga
    14701 ggaccgccac ggcctgcccg tcgagcgtct ttatgtggcc aagttgctgt acggactggc
    14761 cgcgctggcg gaggagggcg ccttcccgcg cgggacgacc gtggcggcgg tgatcaccgg
    14821 ccggccgttc ccctgaccgg tgccggtcag gccgtctccc ggtaggccgc cgcctcctcc
    14881 aggtccaggc gccgcagcag ggtgcgcagc atctcgtcgt cgatgtagcg gccgtccctg
    14941 agcttcacga acacctcgcg ctcggcgctg atcatctcgc gggagagccg gcggtaggtg
    15001 tcgtcgacgg tctcgccggt gaccgggttg acctggccga ggcgttccca gacggcattg
    15061 cggcggcgtt cgaggaccgt gcggaggcgg tcggcgagcg gcggcggcag ggtgttgcgc
    15121 tcgtcggaga gcaggtcgtc cagccgctgc tcggcggcgc gggaggcctg tgcctgggcg
    15181 ttggcctcgg cgagcgtctc ggcctgggtg tcgcggccgg ggaacttcag caggcggatc
    15241 agcggcggca gcgtcaggcc ctgcacgacc agcgtgccga tcacggtggt gaaggtgagg
    15301 aagaggacca ggttgcggtg cgggaacggt tcctcgccgt cgtgcagggt gagcgggatg
    15361 gagaaggcga tggcgaggga gacgacgccc cgcatgccgg cccaggcgat gacgacgggc
    15421 ccgcgccagg tggggttgtc ctcgcgctct ctgatccgcg ccgacagcag gcgcggcagg
    15481 aaggtcgccg ggtacaccca caggaagcgg gtcgcgacga cgacgaggaa gagggcgacc
    15541 gcgtaccagg cggcctcggc accctcgtac tcgccgagcc cgcgcagcac gaactgcagc
    15601 tgcaggccga tcagcgcgaa gaccgcggac tccaggacga aggcgaccat cttccacacc
    15661 gcctcctcct ggaggcgggt ggcgaagtcg acctcccagg cgcggtggcc gaggtagagc
    15721 gccacgacga cgacggcgag gacgccggag gcgtggaact gctcggcggc ggcgtaggcg
    15781 acgaacggga tgagcagcga gagcgtgttc tggaggaggg gttccttcag gtgcgtgcgc
    15841 agccagtgga tcggcgccat gaggacgagg cccacggcga cgccgccgac cgaggcgatc
    15901 aggaactccc tgatgccgcc cgcccaggag gcgccctcgc cgatcgcggc ggcgacggcg
    15961 accttgtagg cggtgatcgc ggtggcgtcg ttcaagaggg actcgccctg gaggatcgtg
    16021 gtgatcctgg acggcaggcc gacccggcgg gccaccgcgg tggccgcgac cgcgtccggc
    16081 ggcgcgacca ccgcgcccag caccagcgcc gccgtcagcg gcagcccggg cacgagcgcg
    16141 taggcggcga gcccgacgac gacggtggcg aacagcacgt acccgacgga gagcagcgcc
    16201 accggccggg tctgcgcgcg caggtcgagg taggagctgt cggtggccga cgtgtacagc
    16261 aggggcggca gcagcagcgg caggaccacg tccggttcga gggtgtagtc ggggacgccc
    16321 gggaggtacg acaccgccag gccgaccgcg accagcagca gcggcgccgg cacgggggtg
    16381 cgccgggcca ccgcggcgat cgcggcactc cccgccacca gcaacagcag cggcatcacg
    16441 tccatcggcc tcgcccaccc tctttttccg cgcggtcgtc cgcacagccg tcgtaatctg
    16501 gcaatcatga aacagtgcac gcacgcggac gcgctgccgc accccgaacc ggcgccgctg
    16561 agcgagacgt gtccggagtg cctgcgggac ggcacccacc ccgtgcagct gcggctgtgc
    16621 ctgacgtgcg ggcacgtcgg ctgctgcgac tcctctccgg gccggcacgc gacggcccac
    16681 cacgcggaca ccgggcaccc ggtgatgcgg accttcgagc ccggcgagga ctggcgctgg
    16741 tgcttcgtgg accatgtcct ggtgtgagtc cggcgggtac ggttcggacg tctgacgtct
    16801 gggtacgtca aaccggcgcg cgcttctccc aattggggcc gcccaccctc tagccacgga
    16861 gcgtatccgg agctttacta tgagtgacgg caaggggttg gggtcctggg gacaggaaag
    16921 ttcagagcgc ggtagcgtca ccgctgaacc acacatcgcg ttaccccggg gggcgaccct
    16981 cggccccgaa cagcttgtac caccttggag gtgagggtgt cccacatcga cggcgagccc
    17041 gtgacccagg acttcgtgga agtccggctg ccggccgcgg gtgcctacct gtcggtgctg
    17101 cggacggcca cggccggtct cgcggcccgt ttggacttca ccctcgacga gatcgaggac
    17161 ctgcgcatcg cggtggacga ggcctgcgcg atcctgctcc agcaggccgt gcccgggtcg
    17221 gtgctctcct gtgtgttccg gctcgtcgac gactcgctgg aggtcaccgt ctcggcgccg
    17281 accacggacg gccacgcccc ctcgcgggac accttcgcct ggaccgtgct gtccgcgctg
    17341 gcgggcaagg tctcctccgc cgtggacgag gacaagactg tgtcgatcag cctctacaaa
    17401 cagcgcggcg cgggacccgg gccggcgtga ggaacgggga cgggccggtg cgggacgagg
    17461 agcgcggcac acgggaactg cctcccgagg acgccctggg ggcccaggag ggctcccggc
    17521 gcatggctga cggcatcgac ggcatcccgg aacaggcccg gccgcatccg gtggacgacc
    17581 ccgccgaggc gggcgtcccc gacggcgggc gacgggggca cgacggcgcc gcgcagagca
    17641 cgcctgagga cgagcggatc ggggtcaccc ctgtccgggc accggcgagg gctcggggaa
    17701 gggcaacggg cgggacgatg agcgagcacg agcgaaacgg cgagcacgac gcgccgggcg
    17761 cgcagaacgc gccgggcgtg cggcacgacc cgcaggaccg cagcggcgcg cgggcgctgt
    17821 tcgtcgagct gcgcggcctg aaggagggca gcccggagta cgcggagctg cgcaaccggc
    17881 tggtccgcat gcacctgccg ctcgtggagc acctcgcgcg ccgtttccgc aaccgcggcg
    17941 agccgctgga cgacctcacc caggtcgcga cgatcggcct gatcaagtcg gtcgaccggt
    18001 tcgacccgga ccgcggggtg gagttctcga cgtacgcgac cccgacggtc gtcggcgaga
    18061 tcaagcggca cttccgcgac aagggctggg cggtgcgggt gccgcgccgg ctccaggagc
    18121 tgcggctgtc gctgacgacg gccacggcgg agctgtcgca gcagcacggc cgctccccca
    18181 cggtgcacga gctggccgag aagctggcca tctcggagga ggaggtcctg gagggcctgg
    18241 agtcggccaa cgcctactcc acgctgtccc tggacgtccc cgacaccgac gacgagtccc
    18301 ccgcggtcgc cgacaccctc ggcgcggagg acgaggcgct ggagggcgtc gagtaccggg
    18361 agtccctcaa gccgctgctg gaggacctgc cgccgcggga gaagcggatc ctgctgctgc
    18421 gcttcttcgg caacatgacc cagtcgcaga tcgcgcagga ggtcggcatc tcgcagatgc
    18481 acgtctcgcg gctgctcgcg cggacgctgg cgcagctgcg ggagaagctc ctcgtcgagg
    18541 agtgagccgc ccggcaggct cctgccggag gccgggtccc gggttacttc tgggcgccgc
    18601 cgggcccgcg gatcccgagg gcccgggtgg tctccccgtt caccagcagg accagcgagg
    18661 tgacggcgac gacggcgagg acgatcccga ccgggatgcc ggtgccgtcg gaggtcagca
    18721 ggttgtacgc caccggcagc gccatgatct gcgtgatgac ggccgggccg cggctccagc
    18781 tgcggcgggc gagcagtccg cgcgcggcca gcagcggcag cagcgcgagc acggccaggg
    18841 tgatgccgcc ggtgacggcc tgctgccggt cgtccgggtc gccggtgagg ccgaggacga
    18901 gcatccagac cccgccggcg accagcgcga gcccctccag ggcggcgagc gcggcggcgt
    18961 acgtcaggcg ccgcgggcgc gggccggcgg gctgttcggt gctggtggtc tgctcactgc
    19021 tcacccctga agggtagccc tcacgagggg ccgctcccgg ggccggactc ccgaccgctc
    19081 ccgggcccgg gctcttaccg gatccctacc tcgcgctggg cgcggtaccg cccagtaggt
    19141 accctgcacg tcatgcgtgc acttctcgtg gtcaatccgg cagctaccac caccagtgca
    19201 cggacgcgtg acgtgctcat ccatgcgctg gccagcgaga tgaagctgga ggcggtcacc
    19261 accgagtacc gcggccacgc ccgcgacctg ggccggcagg cggcgctcgc cgaggacatc
    19321 gacctcgtgg tggcgctcgg cggcgacggc acggtcaacg aggtggtcaa cggcctgctg
    19381 cacgccggcc ccgatccgga gcggctgccc ggcctggccg tggtccccgg cggctccacc
    19441 aatgtcttcg cccgcgccct cggcctgccg aacgacgccg tggaggcgac cggcgcactg
    19501 ctggacgcgc tgcgcgaggg cagcgagcgc acggtcggcc tgggcctgac ctcgggcacg
    19561 ccgggcacgg aggacgcgga ggtgccgcag cgctggttca ccttcaacgc cgggctcggc
    19621 ttcgacgcgg gcgtggtggg gcgagtcgag cagcaccgcg agcgcggcag gaagtcgacg
    19681 cacgcgctct acgtccgcca ggtggtgcgc cagctgctgg gcgagccgaa ccgccggcac
    19741 ggcacgatca cgctggagcg ggcgggtgag gaaccggtca cggaactcgt actttccata
    19801 gtctcgaaca catcaccgtg gacgttcctg ggtaaccggc ccatctatgc gtctcccaag
    19861 gcctcgttcg acaccgggct ggacgtgttc ggtctcagcc gactgtccac cgcctcggtt
    19921 gcccggtatg gcacccagtt gctcacttcg tccccggagc gcggaccgca cggcaagcac
    19981 gcggtcgcgc tgcacgatct ggaccagttc accttgcatt cgaaggtgcc gctgcccctc
    20041 cagatggacg gtgaccacct gggcctgcga accagcgtga cgttcacagg tgtacgccgt
    20101 gcactgcgtg tgattgtgtg agcagaacgg gccaaagtcc tttcactcga acgtttaggc
    20161 caggatccac cccatggaag tacggctgtg acctagtcga caccgaagaa tcaaaaaaaa
    20221 ctttccggaa ggggttgtat ccgccgctga ggtttgcgag tctctacgtg gcgatcggga
    20281 cggcccgcaa caccggcctc cactgatcac cagaacccct ctacaaaccc aggaccacgc
    20341 cggggaaccc ggcggtcggc ccttcacttg ttgagggatt cgtgaaagcg ttcacattca
    20401 caagcaccct gcacagtcat accaaggaga ggtagcagcc atggactggc gtcacaacgc
    20461 cgtttgccgc gaggaagacc ccgagctctt cttccccatc ggcaacaccg gtcctgcgct
    20521 gctgcagatc gaggaagcca aggccgtctg ccgtcgctgc ccggtgatcg agcagtgtct
    20581 gcagtgggcg ctcgagtccg gccaggactc cggcgtctgg ggtggtctca gcgaggacga
    20641 gcgccgcgcc atgaagcgcc gtgccgcccg caaccgggcc cgtcaggcct ccgcctgaca
    20701 cacgcacccc tgctgacagc ctgagcttgg cggcgcgtac agcgtgtacg catctcccgc
    20761 ccccgagccg cagcgcgcag tacccccgac gcgctttacg tagcagagca gcagtcgagc
    20821 atcagcctcg gaccaatggc ggtccggggc tttttgctgc ccggacacgg agtgtgacgg
    20881 cgccctcgac gcccttgtgg cgcggccact tgggctgccc gggcgcgggc cgctacttct
    20941 gtgcccgcac cgggatgtcc aggatcacct gcgtgccccg ctcgggcgcc gggaccatgt
    21001 cgaagctgcc gcccagttcg ccctcgacca gggtccgtac gatctgcagg cccaggttgc
    21061 cc
//
