LOCUS       NZ_BNBR01000001        38502 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces griseosporeus strain JCM 4766 sequence01, whole genome
            shotgun sequence.
ACCESSION   NZ_BNBR01000001
VERSION     NZ_BNBR01000001.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces griseosporeus
  ORGANISM  Streptomyces griseosporeus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 2104813)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 112X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014656055.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 05:04:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,365
            CDSs (total)                      :: 7,282
            Genes (coding)                    :: 7,186
            CDSs (with protein)               :: 7,186
            Genes (RNA)                       :: 83
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 96
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 96
            Pseudo Genes (frameshifted)       :: 41 of 96
            Pseudo Genes (incomplete)         :: 61 of 96
            Pseudo Genes (internal stop)      :: 11 of 96
            Pseudo Genes (multiple problems)  :: 15 of 96
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:46:46
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 373472
            Orig. end                         :: 411974
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BNBR01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..38502
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..38502
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="neighbouring"
                     /product="lassopeptide"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..22691
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22691
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12691](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12691)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            271..834
                     /locus_tag="IE308_RS01630"
                     /old_locus_tag="GCM10018783_03550"
     CDS             271..834
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019056911.1"
                     /locus_tag="IE308_RS01630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03550"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_190216265.1"
                     /transl_table=11
                     /translation="MSVIVIEFVTLDGIVSDPDGSAGTPLGGWAFQYGPEAVAGDKFRL
                     GRTLDEGVLLLGRATWQLFSRLWPGRDDPFATRMNAVPKLVASHTLTPTDLSAWSNSQL
                     LDGDLVDTVKRERRDVVVTGSLSVVDRLRAADLVDEYRLLTFPTVLGTGRRLFPADGPR
                     AELECVGAERVGAAVLTRHRRATR"
     gene            complement(943..1164)
                     /locus_tag="IE308_RS01635"
                     /old_locus_tag="GCM10018783_03560"
     CDS             complement(943..1164)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130915.1"
                     /locus_tag="IE308_RS01635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03560"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_190216266.1"
                     /transl_table=11
                     /translation="MPIAVDIDVMLARRKMSVGELADRVGITPANLAVLKNGRAKAVRF
                     STLAALCEVLECQPGDLLRWEPEVAPVE"
     gene            complement(1164..1655)
                     /locus_tag="IE308_RS01640"
                     /old_locus_tag="GCM10018783_03570"
     CDS             complement(1164..1655)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019765797.1"
                     /locus_tag="IE308_RS01640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03570"
                     /product="DUF2975 domain-containing protein"
                     /protein_id="WP_190216267.1"
                     /transl_table=11
                     /translation="MGKLTVRALRAVLGVVLVGTLFVQGLMVWTLVSGSDPEDGTLPLT
                     AFRVITVLGMVAVQVALVCVGRLVTMVRRGTVFSHAAFRYVDGVIGAIVAAALLWFTVT
                     AVNAPGQRDDPGVTVIMAGIGLAILGVALIVLVLRMLLAQAVARDVEASRMQAELDQVI
                     "
     gene            complement(1736..4117)
                     /locus_tag="IE308_RS01645"
                     /old_locus_tag="GCM10018783_03580"
     CDS             complement(1736..4117)
                     /GO_function="GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005476602.1"
                     /locus_tag="IE308_RS01645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03580"
                     /product="Orn/Lys/Arg decarboxylase N-terminal
                     domain-containing protein"
                     /protein_id="WP_190216268.1"
                     /transl_table=11
                     /translation="MSTGTILMAARETNAGGGAVAEQLRRIAKELEERGLHVRWAADAR
                     DAQAVLRTEAGLAGALVAWDLNPRPGPAGAEGGGAEVLSAIGRRFTDLPVFLLMPQDTE
                     TGGTGSDTDGDFEQLPLWVAEVVCGYVWPLEDTAAFIAGRVAGAARQYQDGVLPPFFKA
                     LRRFDDAHQYSWHTPAHAGGVAFLKSAAGRAFFDYYGERLFRTDLSISVGELGSLFEHN
                     GPIGEAERNAARVFGAERTYFVLHGDSTADRMVGHFSVMRDEIALVDRNCHKSVLHGLV
                     ISGARPVYLVPTRNGYGLAGPLPPARTDGDAVRARIAGHPLAAGALTPEAQYAVVTNST
                     YDGLCYDTVQVARTLAPSTPRLHFDEAWFAYARFHPLYQGRYGMAVGPDTFDDPARPTV
                     FATQSTHKLLAALSQTAMVHIKPSPRAPVAHERFNEAFMMHGTTSPLYPAIASLDIATA
                     MMDGPQGRALLDEAITEAIRFRRAVVRTGRRIAGAGDRPGWFFGVWQPDTVTDPATGER
                     IDFLDAPPSLLAEEPRCWHLEPGAGWHGFEGLTEGYCMLDPVKVTLTCPGVTAAGETAP
                     WGIPARVLTAYLAGRGIVVEKTDSYSTLILFSMGITKGKWGTLMDALMDFKALYDDDTP
                     LDQVLPGLVHAHPHRYTGLTLKQLCQDMHEHLTEADLIDALDTAFRELPEPVAPPQHCY
                     QRLIRGGTERVTLAEAAGRVAAAMVTVTPPGIPVLMPGEAIGTADGPLLRYLTALEAFD
                     RAFPGFHSETHGVTLDPTTGDYLIECVLPQQEDSDSDETP"
     misc_feature    complement(4074..4085)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            4343..5164
                     /locus_tag="IE308_RS01650"
                     /old_locus_tag="GCM10018783_03590"
     CDS             4343..5164
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017238459.1"
                     /locus_tag="IE308_RS01650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03590"
                     /product="DUF4239 domain-containing protein"
                     /protein_id="WP_190216269.1"
                     /transl_table=11
                     /translation="MSLWLLNHFSTFTLALVTVGGTVVLAVVGSVLLRRRYPSLAGGEH
                     NDMVGVTLGMFGAIYGIILAFVIVTLWTQLDSTQTVVASEATDVALISRDAAAFPPPVR
                     ARVDDALGGYLHAVVEVQWPRMRAGQPSYGATADRLQGVFDTLQAYEPKTAREEVFYEQ
                     AVERLNDVTGQRRARLTMAEQELPPLLQILAFGGALVLIPLTFLYGMRRLRIQLLFVAS
                     VAALVGFSLLLVFVLDRPFAGDLSVSPAPYQQGALARYWHGDLPAAAAGDR"
     gene            5292..5897
                     /locus_tag="IE308_RS01655"
                     /old_locus_tag="GCM10018783_03600"
     CDS             5292..5897
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020138421.1"
                     /locus_tag="IE308_RS01655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03600"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_190216270.1"
                     /transl_table=11
                     /translation="MRKIIVCTFLTLDGVMQAPGGPDEDTGSGFEHGGWQKPVSDDEVG
                     AAIAGWYDVSDAMLLGRKTYEIFASYWPTADPANPFTERMNSMQKYVASRTLTSLEWQN
                     STLLEGDVTEAVRALKESEGGNINVVGSGDLAQTLMRDGLVDEYRLTIHPVIIGSGKRL
                     FADGAIPTALEPVSVTATKGGTVVGVYRPSGKPGYDSY"
     misc_feature    5299..5313
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.18"
                     /tool="antismash"
     gene            5996..6436
                     /locus_tag="IE308_RS01660"
                     /old_locus_tag="GCM10018783_03610"
     CDS             5996..6436
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017238475.1"
                     /locus_tag="IE308_RS01660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03610"
                     /product="VOC family protein"
                     /protein_id="WP_190216271.1"
                     /transl_table=11
                     /translation="MALQRMDNVGIVVEDLEAAVAFFTELGMEVEGKAQIEGLFADQAV
                     GLDGVRSDIAMMRTPDGHGKLELAQYHSPAALGGGADNPPPNTLGLHRVMFAVDDIDDT
                     IARLRRHGAELIGEVAQYEDFYRLCYLRGPSGILLALAEQIS"
     gene            6530..7021
                     /locus_tag="IE308_RS01665"
                     /old_locus_tag="GCM10018783_03620"
     CDS             6530..7021
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014671332.1"
                     /locus_tag="IE308_RS01665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03620"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_190216272.1"
                     /transl_table=11
                     /translation="MPELEPLHADHAPAVLAFELANRAYFAASVPDRGDDFFDRFSERF
                     NALLAEQEAGICAFHVLLGEDGAVLGRFNLVDIEDGAADVGYRVAQHVSGRGVATANVR
                     ELCRLAAVRHGLHTLRAAVALQNAASRKVLLKSGFVPVGPADPAHLSGKPGTWYQRQLA
                     "
     gene            complement(7046..7450)
                     /locus_tag="IE308_RS01670"
                     /old_locus_tag="GCM10018783_03630"
     CDS             complement(7046..7450)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019055551.1"
                     /locus_tag="IE308_RS01670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03630"
                     /product="hypothetical protein"
                     /protein_id="WP_190216273.1"
                     /transl_table=11
                     /translation="MSLTLTDQDKQTLRTAAYGAVSLLAAAGAADSPHRIATQGSIALA
                     SATGPIGHVLAEKSKVVLKGKTTAAMADEVLPALTSTMTLLKKQDEDRAADFRSTVLIA
                     LETATRPTKDTPSPAVTDMIRKITDALDAA"
     gene            complement(7608..8153)
                     /locus_tag="IE308_RS01675"
                     /old_locus_tag="GCM10018783_03640"
     CDS             complement(7608..8153)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964142.1"
                     /locus_tag="IE308_RS01675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03640"
                     /product="kinase"
                     /protein_id="WP_190216274.1"
                     /transl_table=11
                     /translation="MTAVKVGTKETRLIVLRGNSASGKSSVAAGLRERFGRGIALVAQD
                     NLRRIVLRERDRPGAANIGLIELTARYALDAGFHVVVEGILYADRYGDMLARLRADHRG
                     PTHGYYLDVPFDETLARHATKPIADDVDARQLRDWYRPRDLLPGGVETVIGADSALHET
                     IDHIMLDTGLAHLPAVDR"
     gene            complement(8219..8611)
                     /locus_tag="IE308_RS01680"
                     /old_locus_tag="GCM10018783_03660"
     CDS             complement(8219..8611)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677532.1"
                     /locus_tag="IE308_RS01680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03660"
                     /product="Imm7 family immunity protein"
                     /protein_id="WP_190216275.1"
                     /transl_table=11
                     /translation="MFEYHGWITVRETAADDDDEPRLQQIVDELRLHIARMDSPYLLDL
                     RWMNGEPFVHLGGFSNHRLPDVIQLFEHVAAVAPGSYGLLHVHDDEEPGHGNDVRVLRL
                     ARGRVTQHTEPLLSPYIPTVEDPFLG"
     gene            8820..9047
                     /locus_tag="IE308_RS01685"
                     /old_locus_tag="GCM10018783_03670"
     CDS             8820..9047
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003987694.1"
                     /locus_tag="IE308_RS01685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03670"
                     /product="hypothetical protein"
                     /protein_id="WP_190216276.1"
                     /transl_table=11
                     /translation="MADTQVWECVGRGDGARCPYGAVLTIDAGVVEYRCDDCRHYWELD
                     ETEPERRATAEDGLTLPVGDPREAGPGAAA"
     gene            complement(9096..9896)
                     /locus_tag="IE308_RS01690"
                     /old_locus_tag="GCM10018783_03680"
     CDS             complement(9096..9896)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009192535.1"
                     /locus_tag="IE308_RS01690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03680"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_190216277.1"
                     /transl_table=11
                     /translation="MSDLAESVESMEQLALVWRSMVLDRDADADVRDLPGIAVRWADCR
                     FAFWNALTLTDVGADARLLGERLAKAAEIMRSKRQPGFLWVFEDLLDEDARATLETAAE
                     QAGLQYAFPGTGMAGDLLPLADPVHPDLTFVRVTTDEQVRAYADLNSRGYGFPLEAGRD
                     GLVGSALWKEEVHAYLALRDGEPVACAGAIPADGRLFVALVATDPQWQRRGYGEAVTRK
                     ALHEGAQATGLTRATLHATVAGAPVYPRIGFRPNSRIGFYGLRD"
     misc_feature    complement(9889..9902)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.74"
                     /tool="antismash"
     gene            complement(10001..10417)
                     /locus_tag="IE308_RS01695"
                     /old_locus_tag="GCM10018783_03690"
     CDS             complement(10001..10417)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010047207.1"
                     /locus_tag="IE308_RS01695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03690"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_110635249.1"
                     /sec_met_domain="PF13471 (E-value: 2.6e-27, bitscore: 91.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTSQVVPHDPRSVPLGPRLVTRLAVGCAHLLARQPPTRIRAVLL
                     RLRRGARPATAAEAARARETVLAVSLAAGGQQGCLPRSLATVLLCRLRGQWPTWCVGVR
                     TQPPFAAHAWVEAEGVLVGEGAPAEYFQRFITVD"
     gene            complement(10566..10823)
                     /locus_tag="IE308_RS01700"
                     /old_locus_tag="GCM10018783_03700"
     CDS             complement(10566..10823)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lasso_Fused_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010047209.1"
                     /locus_tag="IE308_RS01700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03700"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_190216278.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.2e-23,
                     bitscore: 79.8, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="Lasso_Fused_RRE (E-value: 2.5e-07,
                     bitscore: 27.5, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.1e-14, bitscore: 50.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTMRLRPGVVTADTEYGMALLDQNSGEYFTLNPTAALIVRTLLAG
                     SSSEETVAELTGRYAVSSEQVEEDITRILEELRAARLLAS"
     aSDomain        complement(10572..10823)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_IE308_RS01700_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.80E-25"
                     /identifier="RREFam002.1"
                     /label="IE308_RS01700"
                     /locus_tag="IE308_RS01700"
                     /protein_end="84"
                     /protein_start="0"
                     /score="79.8"
                     /tool="antismash"
                     /translation="MTMRLRPGVVTADTEYGMALLDQNSGEYFTLNPTAALIVRTLLAG
                     SSSEETVAELTGRYAVSSEQVEEDITRILEELRAARLLA"
     gene            complement(10820..12691)
                     /locus_tag="IE308_RS01705"
                     /old_locus_tag="GCM10018783_03710"
     CDS             complement(10820..12691)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986679.1"
                     /locus_tag="IE308_RS01705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03710"
                     /product="asparagine synthase"
                     /protein_id="WP_190216279.1"
                     /sec_met_domain="Asn_synthase (E-value: 7e-30, bitscore:
                     101.6, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATGASHPPEASWFVVFPDTDAVADLAARAGAPGTRRIPHPSGRP
                     WLIGRWPDHAARTAAHGPARLAVLGQHAVTQEQADRAARAGSPRAADAVARTWPGSHHL
                     IAALDGRTLVHGTVTGVRSLFTARVPGAHGAHLVSDRADVLADLTGADLDEGRLAVHLL
                     SPGILHPLTTQTVWHGVDVVPGDRRVLLDRDGRLRTEHCWSPPSAELPLAEGARLVRER
                     LADAVAVRVTGRELISADLGGVDSTAVVATAARAGAKTVAYTAAVHDVLGDDVTYARRT
                     VAELDGVEHHVVPAPAVPLTFDRVDALDDDLDIPSLYAVNRHRRMYIVERAAERGSPLH
                     LSGMGGDELFSGASAHVHGLLPRHPRTAWRLARGFTSRHRWSRRTALAQLLDRRPYGSW
                     LAEVARDLTYPQPPMSVPLFTWGTPPRLPPWATARAVEAVRDLIHEQAEDVRPLAPGHG
                     GHREIATLRTLARFARHVQQMSEPLGVTFAAPYYDDLLVEAAFAVRPQDRITPWRYKPL
                     IEEAMRGVVPEAGRTRTTKAHAAFEEETGLRRHRSALLALWEDSRLRELGLVDVAPLRD
                     WCLRPLAADLESALLHPTVGCEVWLRARERHHGPPRPTRTDTGGTPT"
     misc_feature    complement(12786..12803)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.44"
                     /tool="antismash"
     misc_feature    complement(12792..12806)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.28"
                     /tool="antismash"
     gene            complement(12828..12935)
                     /locus_tag="IE308_RS01710"
     CDS             complement(12828..12935)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039305.4"
                     /locus_tag="IE308_RS01710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="keywimysin-related RiPP"
                     /protein_id="WP_110635242.1"
                     /transl_table=11
                     /translation="MAYERPTLTKVGDFQKVTGLAGTGSPDLLGGHSLL"
     misc_feature    13154..13169
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.25"
                     /tool="antismash"
     gene            complement(13436..14587)
                     /locus_tag="IE308_RS01715"
                     /old_locus_tag="GCM10018783_03720"
     CDS             complement(13436..14587)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019981160.1"
                     /locus_tag="IE308_RS01715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03720"
                     /product="DUF6215 domain-containing protein"
                     /protein_id="WP_190216280.1"
                     /transl_table=11
                     /translation="MLGFLVRLLPFWVREPLLIVVGSVFGVRIMYLAVRDQDWTPAAIG
                     AVFLVFTAVRVHGVVRAWRARRGAGAAAVAQGALATDAAAPIQAPAQASTSAQAPVPVQ
                     AAAPAVAAQPQPAVQQGTAVQQQGPVQTHVPVEAPAPASTQKPAAEKEPNAWGQAAAAI
                     GVFALIAGVLWAGPRLLPSEDTTPRSVSCPEAGKEELPKAFRDTPRAVTGDELCKLLNS
                     PALAQLLGTPTEKATAASATNNTAPLTDGKVAQPEAEVTFDTYTVNVTATYNHLSVAQY
                     VKLMKYGSEQDVRTLKVLDRRPAVLSSDHTMKISIDLGGSASGGPVEQGPLARTLTVAL
                     DRGDGGGYYDITVWSQSGLLPDDSALLKIAEKVLPAIPDRPAR"
     gene            complement(14692..15276)
                     /locus_tag="IE308_RS01720"
                     /old_locus_tag="GCM10018783_03730"
     CDS             complement(14692..15276)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019908.5"
                     /locus_tag="IE308_RS01720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03730"
                     /product="NPCBM/NEW2 domain-containing protein"
                     /protein_id="WP_190216281.1"
                     /transl_table=11
                     /translation="MSRARAVAACAVTAAAITLGGACGGGTSGPGPTRTVTATAPTVTV
                     TAGGTSETTGESAQSRYLNELDPLTATEGIDTGTAEINGTGFASSVTLACNAAGPVNSA
                     EYNLGRHWTTFTATAGLRDDSPTGGSLTFEVAVDGTRRFRETIRLGASREVRLDIRNAL
                     RLKLTVSYTGQDASSVYYGSWGDAQITGGKP"
     gene            complement(15273..15911)
                     /locus_tag="IE308_RS01725"
                     /old_locus_tag="GCM10018783_03740"
     CDS             complement(15273..15911)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE308_RS01725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10018783_03740"
                     /product="hypothetical protein"
                     /protein_id="WP_190216282.1"
                     /transl_table=11
                     /translation="MTISARLPRHRHRLEVARDWPLLAAAVSALLSFVMLFPPWLSSGD
                     DSQNAFGDALQAAGPALIIVMAVATIASLAVAVTTADRRFVRLALVPSSVLLALYVVKV
                     ADVSELADAYNRLAGSFTDEKVGTGVGLWLGFVFALVTEMFVIYTLVSRWGTGEAPAYP
                     GFGPRKQTPHETLADSDQPRYPTPPDTDPPRYPPPPDHPPDLPREGPDR"
     gene            complement(16044..17222)
                     /locus_tag="IE308_RS01730"
                     /old_locus_tag="GCM10018783_03750"
     CDS             complement(16044..17222)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019523071.1"
                     /locus_tag="IE308_RS01730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03750"
                     /product="DUF3103 family protein"
                     /protein_id="WP_190216283.1"
                     /transl_table=11
                     /translation="MRPRHLRRRGLGAAAAALVALCAGQTLTALPATAATTAPAPTSAV
                     TAAEDQAARAMAGSLTDSVWRARVRTAALASEEVDVTALAAQAGGSRALRSTLTAADRR
                     IATAKGLGAEVGPLLRLRLGDASMRGALTAGTTPWVAAATQDEDATTVTAYDSHGRAHT
                     LDARKAPAHPVYVVDIDSSTALAAGLDVLTGELARYGVHSAEPTAAAARTGTEPSTGHR
                     SPALAATGGFWTTRITAVELSDDEEPWIKGDAEIYTLVTGFGQDGKVRVDPVDMPYLDN
                     DGTVYRPNQILVNWSSYKYDLADAVMMEEDGSTNYHDLAQAIAAALLTITDQGAYIPLV
                     NAVLDAIPADWWTDDPDYVDSWYTLARGDNGTRHGARGNGWMTVQPYYVPEL"
     misc_feature    complement(17327..17337)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            17439..17798
                     /locus_tag="IE308_RS01735"
                     /old_locus_tag="GCM10018783_03760"
     CDS             17439..17798
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020132077.1"
                     /locus_tag="IE308_RS01735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03760"
                     /product="gas vesicle structural protein GvpA"
                     /protein_id="WP_110635227.1"
                     /transl_table=11
                     /translation="MTVATQQGGGGSSGLYDVLELILDRGLVIDAFVRVSLVGIEILKI
                     DIRIVVASVDTYLRFAEACNRLDLEAGPRKPAGITELPGKLTESGARGKTKGALSGAAQ
                     AVADAFQQGRDEGRK"
     cand_cluster    17450..38502
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    17450..38502
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[27449:28502](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(27450..28502)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="2"
     gene            17993..19681
                     /locus_tag="IE308_RS01740"
                     /old_locus_tag="GCM10018783_03770"
     CDS             17993..19681
                     /EC_number="3.6.4.12"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0043138 - 3'-5' DNA helicase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983596.1"
                     /locus_tag="IE308_RS01740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03770"
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="WP_190216284.1"
                     /transl_table=11
                     /translation="MTGERPPKRRTRRLRATAAEVFGWDELRPAQLTAMEWVLEGRDTL
                     VVMPTGSGKSAVYQVPALLLSGPVVVVSPLLALQRDQIAGLPGGDDGPGAVAVNSDLGV
                     AETEAAWDAVRSGAVRFVYLSPEQLAKDEVVRRLAEAEPALFVVDEAQCVSSWGHDFRP
                     DYLRLAQAVRRLGRPPVLALTATAAPPVRQDIVERLGMDSPRHLVTGFDRPNIRLEAHR
                     HLDDAERRRAVVEQAAAGPKPGIVYAATRKDCEFYAGELAALGLAAEPYHAGVRAAERK
                     RIHEAFLAGETDVVVATSAFGMGIDKEDVRYVLHASLPGSLDAYYQEIGRCGRDGRPAL
                     ALLHYRSEDTGMQVYFSGRPPSRGTVDTVVRAVHDHRDDPVRLDGLRRETGLSRTRLTT
                     AVNLLEEAGAVETDTSGAVRPSPGTSPEAAVERAADSAEAHRRMDRSRVDMARAYAETT
                     GCRRRFLLGYFGEEYAEPCGNCDICDAGAAEDGDAPAAGQRPAHPDAGSYPVGAAVLHD
                     QWGRGTVLSEDADRITVLFDDVGYRTLSLDALADRNDLLTVADVP"
     gene            19856..21298
                     /locus_tag="IE308_RS01745"
                     /old_locus_tag="GCM10018783_03780"
     CDS             19856..21298
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.5"
                     /locus_tag="IE308_RS01745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03780"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_229908654.1"
                     /sec_met_domain="Pkinase (E-value: 6.4e-39, bitscore:
                     130.6, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDELQPTDPRQVGRYRITARLGAGGMGRVYLGRSPSGRLVAVKVV
                     RPELADDPDFRRRFAREVAAARKVTGFFTAALVDADPDGPSPWLATAYVPGMPLDTAVA
                     VHGPWPVASVRTLGAGLAEALEAVHAAGLVHRDLKPSNVLIAADGPRVVDFGISVAAEA
                     TALTRTGIVVGTPGFMAPEQLTGKPVTPATDVFALGAVLTYAATGTGPFGTGSAQSLNF
                     RIVYEEPDLSGLPSPGLEIVARCLAKDPAHRPSVTALVEELALPAPDADAPPPTGSDLA
                     DTAWLPGPVALALPATVPASRRPLPPRPATPAPVTPEPGPASPVPPAPAPIPPRPRAAP
                     VVTPPPQARRRSVLPLWIAMASLALGVVLPFVEGDIIVTSLDHGAWPFVVVVLLSMATC
                     VAALVVRRRATASRGPLWVRIVHTVTTTLTTGLFAALLSSQYARQGKLDQLDVGACFFG
                     LGCLALLYSVFRFPASRRRPAP"
     gene            complement(21304..22098)
                     /locus_tag="IE308_RS01750"
                     /old_locus_tag="GCM10018783_03790"
     CDS             complement(21304..22098)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (8-124). E-value: 1.7e-08. Score:
                     26.5. Matches aSDomain:
                     nrpspksdomains_IE308_RS01750_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004979307.1"
                     /locus_tag="IE308_RS01750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03790"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_190216285.1"
                     /transl_table=11
                     /translation="MQIDLTGRTALVTGSTQGIGAAIAAGLARAGARVAVNGRSEERVR
                     EAVDRLRGEVPGADLVPAAADVSTAEGADRLAQSLPDVDVLVNNLGVFGSADALEISDA
                     EWRRYFEVNVLAAVRLTRMFLPGMMERGWGRIQYIASDSAVVVPAEMIHYGMTKTSLLA
                     VSRGFAKKAAGTGVTVNSVLAGPTHTGGVEDFVYELVDRSLPWDEAQRAFMREHRPQSL
                     LQRLIEPEEIAHMVVYLSSDQASATTGGALRVDGGYVDAILP"
     aSDomain        complement(21727..22074)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS01750_PKS_KR.1"
                     /evalue="1.70E-08"
                     /label="IE308_RS01750_PKS_KR.1"
                     /locus_tag="IE308_RS01750"
                     /protein_end="124"
                     /protein_start="8"
                     /score="26.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TALVTGSTQGIGAAIAAGLARAGARVAVNGRSEERVREAVDRLRG
                     EVPGADLVPAAADVSTAEGADRLAQSLPDVDVLVNNLGVFGSADALEISDAEWRRYFEV
                     NVLAAVRLTRMF"
     CDS_motif       complement(21979..22068)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS01750_0001"
                     /evalue="3.40E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE308_RS01750"
                     /protein_end="40"
                     /protein_start="10"
                     /score="16.5"
                     /tool="antismash"
                     /translation="LVTGSTQGIGAAIAAGLARAGARVAVNGRS"
     misc_feature    22068..22082
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 26.07"
                     /tool="antismash"
     gene            22294..23034
                     /locus_tag="IE308_RS01755"
                     /old_locus_tag="GCM10018783_03800"
     CDS             22294..23034
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677015.1"
                     /locus_tag="IE308_RS01755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03800"
                     /product="flavodoxin family protein"
                     /protein_id="WP_190216286.1"
                     /transl_table=11
                     /translation="MTASPPAAPDAPPARYDDLRAMVINCTLKRSPETSNTQGLIDRST
                     TILAAQGVRVDVVRAVDHDIATGVWPDMREHGWETDAWPELYRRVMAADILVLAGPIWL
                     GDNSSVMKQVIERLYACSSLLNDAGQYAYYGRVGGCLITGNEDGVKHCAMNVLYSLQHL
                     GYTIPPQADAGWIGEAGPGPSYLDPGSGGPENDFTNRNTTFMTWNLLHLARALKDLGGI
                     PAYGNQRTAWDAGCRHDYENPEHR"
     gene            23123..24205
                     /locus_tag="IE308_RS01760"
                     /old_locus_tag="GCM10018783_03810"
     CDS             23123..24205
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE308_RS01760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10018783_03810"
                     /product="hypothetical protein"
                     /protein_id="WP_190216287.1"
                     /transl_table=11
                     /translation="MNTAEDALIDVVPLGTAPVPERGRVEALAGGGLVVRAPGLVEVHD
                     REDFLAGGAAGARAALRTREPERAVPTPDGGFVVAGVSSVRALDADGGTRWELGHDRWH
                     GADRAHSVPAVSPDGRLVSVVVPRLEPEKEKAALVYDLEPGRNYTWDELLLLDAATGAV
                     LGRRQIRSLASAAVASWGPDGDAVVVSCWTAWQSWSTWWAEPRADGPHLAGATWMHALA
                     GFLPGGRMLTQRYAEYLFPDDDRDELAVYDLRSGEQAALVDLRELAVDPENDEFLSAEV
                     LDGRHVLVPGRVHPAPGVAELRHWLLDAGTLRPLGRLNYPVPVGEDVTALRDGTWLTRD
                     GNRLHRWALGHSGPGGVDAR"
     gene            complement(24238..24879)
                     /locus_tag="IE308_RS01765"
                     /old_locus_tag="GCM10018783_03820"
     CDS             complement(24238..24879)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971431.1"
                     /locus_tag="IE308_RS01765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03820"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_190216288.1"
                     /transl_table=11
                     /translation="MRLTKFGHACVRVEKDGRRLVVDPGGLTDPRALEGADAVLVTHEH
                     ADHFSEETLRAAAERDPALRIWTNTSVAGRLDGLGGRVTAVGEGDAFTAAGFDVRVYGT
                     WHAVIHPDIPRVGNIGFLVDAALFHPGDALTVPDTAVDTLLLPVHGPWSTTGQLVDYVR
                     AVAPQRSYAIHDGALNDIGTAMVGGLLGDNGPGTGAPYRHLTAGTSVEIG"
     gene            24972..25397
                     /locus_tag="IE308_RS01770"
                     /old_locus_tag="GCM10018783_03830"
     CDS             24972..25397
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014146396.1"
                     /locus_tag="IE308_RS01770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03830"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_190216289.1"
                     /transl_table=11
                     /translation="MDDDVLAEDLRQVIGELVRAVRAVDTMPSGEAATLGYLDRSGPLT
                     AADLAALRRVTHQAATKSAKELLADGLVRAEPHPTDGRKQLLHITDSGRARLQRERAQR
                     ANWLNAAIHEALSAEEQRQLRQCVGLLERLTAHITGR"
     gene            complement(25384..26079)
                     /locus_tag="IE308_RS01775"
                     /old_locus_tag="GCM10018783_03840"
     CDS             complement(25384..26079)
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018066.5"
                     /locus_tag="IE308_RS01775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03840"
                     /product="acetoacetate decarboxylase family protein"
                     /protein_id="WP_229908748.1"
                     /transl_table=11
                     /translation="MPPSRPPHPPEPWHLRGDMRAALWLVPRYGLPPWPLPEGARAVSL
                     AGRTPLITFWVDYGDGGDLAYRELLVAVVVRQGAGLAATAVQVWVDDERSLAGGRHLWA
                     IPKEPAAFDFRPLPPDPSPRRGVRTTMTVEAAGRREPDAVALCRDLLRLPLRLPVRAHL
                     LQPRADGTTCRVPLRLTGRPSLSRIRTRVHPEGPLAYLTGHRPVAAVSLADFRFRIGPA
                     VTSGEVTAP"
     gene            complement(26216..27382)
                     /locus_tag="IE308_RS01780"
                     /old_locus_tag="GCM10018783_03850"
     CDS             complement(26216..27382)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152514.1"
                     /locus_tag="IE308_RS01780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03850"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_190216291.1"
                     /transl_table=11
                     /translation="MTFTEASMDALRQSGDELADAVVATLFERGEVGKFNTLMRYVSTA
                     GAPLPDGLPDVAREYLHTTGVPPSWVDWGEMEKARLFFLDNNVHISTALSFASMPACYV
                     VPHVARLLSATHGLDYPSKRMAETGQFTVHLMRPDAFEAGGRFLPAAQKVRLLHASIRH
                     HLQREDRWDTGTLGTPICQEDMIGGQMFFSLLVLDSLHRLGIHMSVEGAEAYFYAWRVV
                     GAILGVDQDAVPKTLEEAREFLDLYMVRHMGPSEEGVHLTRQLIDLYEEVVPGTFFDPV
                     VSALIRYLIGDTCADWLRVPRTTWDSVVKVVPGLLGVLETIEDRSPLGAWALDRLGHLT
                     TVFELSSLTRGRVMHYAIPEELKKDFGVAGGVPRTQRWAPPAPTVAPR"
     gene            complement(27450..28502)
                     /locus_tag="IE308_RS01785"
                     /old_locus_tag="GCM10018783_03860"
     CDS             complement(27450..28502)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978297.1"
                     /locus_tag="IE308_RS01785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03860"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_190216292.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.2e-38, bitscore:
                     128.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDRWDPAGFKDRVDTLLAGFLAAEAERFLAIDGALAPVAGQLRV
                     AAGHGKRLRAAFCYWGWRAAGQPDSDALLRAAASLELVHAAAVVHDDLIDDSPLRHHLP
                     TAHVALHTAVRDRPRPRAAARALAMLVGDHLMALAGQLFATSGLPAAYLTRARPVWADL
                     ARELIAGECLEILATGARPDPEVSLKVVRYKTAKYTVEQPLLIGGLLAGAPPGLRAALS
                     AYGLPLGEAFQLRDDLLGLFGEPARTGKASLDDIRGQRPTALLAAAWRAALPAQRERLA
                     GVLGRRDVTEEDLREVRELMLTLKAPQQVEDMITARVRDAVGHLDRLSLPHTARRALTD
                     LAHSATDRHH"
     misc_feature    complement(28374..28376)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(28495..28812)
                     /locus_tag="IE308_RS01790"
                     /old_locus_tag="GCM10018783_03870"
     CDS             complement(28495..28812)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011027208.1"
                     /locus_tag="IE308_RS01790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03870"
                     /product="polyprenyl synthetase"
                     /protein_id="WP_229908655.1"
                     /transl_table=11
                     /translation="MTHAPRDGRVDDRGDGRDGDRGLDEQAVLLVAGLADLAVTTIGSA
                     MGTLRGLLRRSDGPDLARDAHQDLMARGRLVLDRRAAGPAHLEVLAQHARARQAASSGD
                     V"
     misc_feature    complement(28941..28954)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.03"
                     /tool="antismash"
     gene            complement(29002..29709)
                     /locus_tag="IE308_RS01795"
                     /old_locus_tag="GCM10018783_03880"
     CDS             complement(29002..29709)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005473467.1"
                     /locus_tag="IE308_RS01795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03880"
                     /product="B3/4 domain-containing protein"
                     /protein_id="WP_190216293.1"
                     /transl_table=11
                     /translation="MTAFRIAPAVADAFPDTLIALVTATGLRGHEPWPDTDSALEELER
                     QLADGTWQPADEADPRIEAWHTAYRSFGTNPRRIRPSVDALGRRLAKRGTLPRINPAVD
                     SYNAVSVRHGLPAGAFDLDHVAGDVDIRHAAGTETFTPLGEPDTVEHPKPGEIVYADAT
                     GVLTRHWNHRDAHRTRVTADSTRVAFLLETLHAGRDGDLLKLAADELQGLLAPHAERTA
                     VHYLSPEQPQAAV"
     gene            complement(29765..30412)
                     /locus_tag="IE308_RS01800"
                     /old_locus_tag="GCM10018783_03890"
     CDS             complement(29765..30412)
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005473466.1"
                     /locus_tag="IE308_RS01800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03890"
                     /product="FMN-binding negative transcriptional regulator"
                     /protein_id="WP_190216294.1"
                     /transl_table=11
                     /translation="MFIQPWDASLDDAEWQAWIAEGHDFGILSVNGPPGHAPATVPTHF
                     TGDGGDLLIHLARPNPVWAFVEADPNVTFTVIGDYAFIPGPWRAKPGIPPTDGVPTSYY
                     AAVQFTCRAHAVDDPEAKAELLRRQLAHFQPDGDHAPVAADRPPYGRMLSGIRGLRLEV
                     TDVRAKFKYDDHKPVEHRTAVAGHLTTRDQGLDTATARQQLRRLDRIGPWQP"
     gene            complement(30495..31329)
                     /locus_tag="IE308_RS01805"
                     /old_locus_tag="GCM10018783_03900"
                     /pseudo=""
     CDS             complement(30495..31329)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018383745.1"
                     /locus_tag="IE308_RS01805"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03900"
                     /product="EamA family transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIALLLALGSSLAYVRRLPRRPRRPQGPCAADRAGGRPGQPRGRA
                     AAVAGARRVVQYGGPRLGRRVRGRLGRRLRPAVPHPRDRPGERPLAGDRTRLRRAAGRR
                     RPSPGRTPDRRRRHRAAPRPAGRRPGQRRTRRGLGPPLPHGAAVGLRRGRRHRPAARLP
                     APGAVRQRRRPADRRPGRLLRRHPGRRRPPAPQARPRAPRLRAVGHRGSPGLPGEPALP
                     ARRPQRRPHRRRRHHRPLPGRHRPAGSRCPRRTHPPRPARRPRHGRRRGQPPRPHL"
     gene            31448..32032
                     /locus_tag="IE308_RS01810"
                     /old_locus_tag="GCM10018783_03910"
     CDS             31448..32032
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010473767.1"
                     /locus_tag="IE308_RS01810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03910"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_190216295.1"
                     /transl_table=11
                     /translation="MAETATALRTVAHNVRAARIRAGLSLEELGRRAQVSKGALVALEK
                     AQGNPNLATLVRLADTLGISVSALMQGPHEGRVRIAAADAVAPLWTGERGSEARLMLTT
                     SGPAPVEVWRWRLEPDEEYPSHPHQAGVVETVSVTAGRMVLVVDGTEHTLEAGQTATFD
                     GDTSHTYRGAGTGPCHLIMTVHLPPGPAAGG"
     gene            complement(32162..32677)
                     /locus_tag="IE308_RS01815"
                     /old_locus_tag="GCM10018783_03920"
     CDS             complement(32162..32677)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006123677.1"
                     /locus_tag="IE308_RS01815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03920"
                     /product="hypothetical protein"
                     /protein_id="WP_229908657.1"
                     /transl_table=11
                     /translation="MYEIMLDAELSKAFDVWSGYLNARTGEDPEVRAQLGALLESARTA
                     AAEGDPAYARTLLGEMYDEARDAGLAFAPVEPDPCAADCQARDYAKDELRQVLPLQLRE
                     DLDSVALYLRVTGRRLRTAPGLDAATREDILYVCARAGMALDLAHLTAARRELERLEAI
                     ARRCGVEP"
     gene            complement(32861..33127)
                     /locus_tag="IE308_RS01820"
                     /old_locus_tag="GCM10018783_03930"
     CDS             complement(32861..33127)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE308_RS01820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10018783_03930"
                     /product="hypothetical protein"
                     /protein_id="WP_190216296.1"
                     /transl_table=11
                     /translation="MTLYGIKPAYIAGFSFLCLAVGAVLLFRHDGPYWAAIALFVAVAW
                     SNGQWREAGQQDPGQLSTLAFLVMLLAPFLGVAALVWGLALEL"
     misc_feature    33168..33182
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.71"
                     /tool="antismash"
     gene            complement(33239..33631)
                     /locus_tag="IE308_RS01825"
                     /old_locus_tag="GCM10018783_03940"
     CDS             complement(33239..33631)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE308_RS01825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10018783_03940"
                     /product="hypothetical protein"
                     /protein_id="WP_190216297.1"
                     /transl_table=11
                     /translation="MAGEAEYPELIRDEDPWQGLDVMGSVHLRVWQWEAGRLTAVISGP
                     GAMRAEGVEEAFARLRAEYPQATVELFHHHPGDWIDMAFYAELAREADGSVTRTQVFGN
                     ELARRLGPSLYATEDPEDETGGYGGP"
     misc_feature    33591..33604
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     gene            complement(33667..34434)
                     /locus_tag="IE308_RS01830"
                     /old_locus_tag="GCM10018783_03950"
     CDS             complement(33667..34434)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (29-126). E-value: 2.1e-11. Score:
                     34.4. Matches aSDomain: nrpspksdomains_IE308_RS01830_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069367.1"
                     /locus_tag="IE308_RS01830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03950"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_190217321.1"
                     /transl_table=11
                     /translation="MPEAYERHLVPVLFRPFAADLAARAAALRPRSVLELAAGTGVLTS
                     ALLAAVPEASVVATDLNDAMVATGSAREPRARWRQADAQELPFPDGGFDLVVCQFGVMF
                     FPDKRAAFAEVRRVLAPHGRFLFSSWGPLDSHGFDAAVQSALDECMPEGAPQFLREVPH
                     GYTDPSVVAAELADAGLVLAEVEEVTLQGEAESAESVAVGFLTGTPVSAAVQDRADAQA
                     LRAAVARRMTERLGAGRVTAPMTATVYTAHHRR"
     aSDomain        complement(34057..34347)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS01830_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="2.10E-11"
                     /label="IE308_RS01830_oMT.1"
                     /locus_tag="IE308_RS01830"
                     /protein_end="126"
                     /protein_start="29"
                     /score="34.4"
                     /tool="antismash"
                     /translation="PRSVLELAAGTGVLTSALLAAVPEASVVATDLNDAMVATGSAREP
                     RARWRQADAQELPFPDGGFDLVVCQFGVMFFPDKRAAFAEVRRVLAPHGRFL"
     misc_feature    34434..34447
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.79"
                     /tool="antismash"
     misc_feature    complement(34874..34888)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.1"
                     /tool="antismash"
     gene            35110..35535
                     /locus_tag="IE308_RS01835"
                     /old_locus_tag="GCM10018783_03970"
     CDS             35110..35535
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007381705.1"
                     /locus_tag="IE308_RS01835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03970"
                     /product="DUF6003 family protein"
                     /protein_id="WP_110635164.1"
                     /transl_table=11
                     /translation="MTDDAYLFLVDGAAEGPGVPPAELGEPACMDTSAVSAWLAAHDVT
                     AVSPRLRIVPPEETDLIPSGAERLPVPLSEEELTRLRRRQAPAATTAIEDELLAYRDCA
                     DGRDELLARALAAGVPAHRVAELTGEDLRVVQAVAQR"
     misc_feature    35542..35553
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            35668..35922
                     /locus_tag="IE308_RS01840"
                     /old_locus_tag="GCM10018783_03980"
     CDS             35668..35922
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014157830.1"
                     /locus_tag="IE308_RS01840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03980"
                     /product="hypothetical protein"
                     /protein_id="WP_110635161.1"
                     /transl_table=11
                     /translation="MTTQYTNQPTGQQSASTGNVLSIIAIVLGVVSLLFLPIVFGLIGL
                     VLAIVAKTVRHERLSTIAIVVSAVGLIGGMILGALVVNT"
     gene            complement(36073..37044)
                     /locus_tag="IE308_RS01845"
                     /old_locus_tag="GCM10018783_03990"
     CDS             complement(36073..37044)
                     /EC_number="2.7.7.87"
                     /GO_function="GO:0003725 - double-stranded RNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004003700.1"
                     /locus_tag="IE308_RS01845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03990"
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="WP_190216298.1"
                     /transl_table=11
                     /translation="MARTSDIEKAAEVLRAGGLVALPTETVYGLGADAENPAAVSRIFQ
                     VKGRPPTHPLIVHIGGADQLADWVAEVPATARLLAEHFWPGPLTLVLRRGPRVPLEATG
                     GLETVAVRVPDHPAALALLEAFGGGVTAPSANRFGSVSPTTADHVRAELGEAVDFVLDG
                     GPCGVGVESTIVDVTGETPAILRPGGVTREDLEAVLDRPLDVPATSHVRVPGQHPSHYA
                     PSARVVLVEPEQIAAEAQLAQEQGHQVGVLLPSTLVGTPVKAHAVVPVPASMAGYAREL
                     YGFLRELDQRGCDLIIASLPPEEGLGLAIANRLRRAAGPRQS"
     misc_feature    complement(37012..37021)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
ORIGIN
        1 tggggcatgc gggaggtcac cgccaacggg cagcccgcgc tcgccgcgta cgcgccggcg
       61 cccggcggcg ggtaccggcg gcacagtctg cagctcttca ccgtcgccgc cggccgcatc
      121 acgcgcaacg tggtgttcgc cgatccgcgc gtcctcgacg ccttcgagct gccgggcgag
      181 attcccgcgg gcggtttccg ccgggagcga tgagtcaggg cggtgcggcc ggtaggtacc
      241 ggtgagcacc gaaccgaagg gaatcccatc gtgagcgtca tcgtcatcga gttcgtcacc
      301 ctggacggga tcgtgtccga cccggacggg tccgccggta cgccgctggg cggctgggcg
      361 ttccagtacg gcccggaggc ggtcgccgga gacaagttcc ggctcggccg cacgctggac
      421 gagggggtac tgctgctcgg gcgtgccacc tggcagctgt tctcccggct ctggccgggc
      481 cgcgacgacc cgttcgccac gcggatgaac gccgtcccga agctggtcgc ctcccacacc
      541 ctgaccccca ccgacctgtc ggcgtggtcc aactcccagc tgctcgacgg tgatctggtc
      601 gacaccgtca agcgcgagcg tcgggacgtg gtcgtcaccg gcagcctgag cgtcgttgac
      661 cggctgaggg cggcggacct ggtcgacgaa taccggctgc tgaccttccc cacggtcctc
      721 ggcaccggcc gacgactctt cccggccgac ggcccccgag cggagctgga gtgcgtgggc
      781 gcggagcggg tgggcgccgc ggtcctcacc cggcaccgga gggcgacccg gtgaccgccc
      841 tccaaggcga cggggcccgt cccgccgcgg tacctcgcag acctggggtt gacagggtgc
      901 ccatcgcccg ctcgcccggt caggacaggc gggaagggtg cctcattcga ccggggctac
      961 ctcgggctcc cagcgcagca ggtcgcccgg ctggcattcg agcacttcgc agagcgcggc
     1021 gagcgtcgag aagcgtacgg ccttggcgcg gccgttcttg aggacggcca ggttggcggg
     1081 cgtgatcccc acgcggtccg cgagttcgcc cactgacatc ttgcgtcgcg ccagcatcac
     1141 gtcgatgtcg acggcgatcg gcatcagatc acctggtcca gctcggcctg catccgcgag
     1201 gcttcgacgt cacgtgcgac ggcctgggcg agcagcatcc gcagtacgag cacgatgagc
     1261 gcgacgccca gaatggccag gccgatcccg gccatgatga cggtgacgcc ggggtcgtcc
     1321 cgctggcccg gtgcgttgac ggccgtgacc gtgaaccaca gcagggcggc cgccacgatg
     1381 gcgccgatca cgccgtccac gtagcggaag gcggcgtggg agaacacggt tccgcgccgc
     1441 accatcgtca ccagccgccc cacacagacc agggcgacct ggaccgccac catgccgagg
     1501 acagtgatca cccggaacgc ggtcagcggc agcgtcccgt cctccgggtc gctcccgctg
     1561 accagcgtcc agaccatcag gccctgcacg aacagggtgc cgacgagcac caccccgagg
     1621 acggcgcgca gcgcacgcac ggtcagcttt cccatgacca gcccttccat cgaatcccaa
     1681 caggaatcta tcgagattcg ataggaggat caatcgtcgg cacgccgtcc gaaggttagg
     1741 gcgtttcgtc gctgtcgctg tcctcctgtt gtgggagtac gcactcgatg aggtagtcgc
     1801 cggtggtcgg gtcgagggtg acgccgtggg tctcgctgtg gaagccgggg aaggcgcggt
     1861 cgaaggcttc cagtgcggtc aggtagcgca ggagcgggcc gtcggcggtg ccgatggcct
     1921 cgccgggcat caggacgggg atgccgggcg gggtgacggt gaccatcgcg gcggcgaccc
     1981 ggccggccgc ctcggccagg gtcacgcgtt ccgtcccgcc gcggatcagg cgctggtagc
     2041 agtgctgcgg gggtgcgacg ggctcgggga gttcgcggaa ggcggtgtcg agggcgtcga
     2101 tcaggtcggc ctcggtgagg tgttcgtgca tgtcctggca caactgcttg agggtgaggc
     2161 cggtgtagcg gtgcgggtgt gcgtgcacga ggccgggcag gacctggtcg agcggggtgt
     2221 cgtcgtcgta gagggccttg aagtccatca gggcgtccat gagggtgccc cacttgccct
     2281 tggtgatgcc catggagaag aggatcaggg tgctgtagct gtcggtcttc tccacgacga
     2341 tgccgcggcc ggcgaggtag gcggtcagga cgcgcgccgg gatgccccac ggtgcggtct
     2401 ctccggcggc cgtgacgccg gggcaggtga gggtcacctt gaccgggtcc agcatgcagt
     2461 agccctcggt cagtccctcg aagccgtgcc agccggcgcc gggctccagg tgccagcagc
     2521 gcggctcctc cgcgagcagg gagggcggcg cgtcgaggaa gtcgatacgc tctccggtgg
     2581 cgggatcggt gaccgtgtcg ggctgccaca cgccgaagaa ccagccgggc cggtcaccgg
     2641 cgccggcgat gcggcggccg gtgcgtacga cggccctgcg gaagcggatg gcttcggtga
     2701 tggcctcgtc gagcagcgcc cggccctggg ggccgtccat catggcggtg gcgatgtcca
     2761 gcgaggcgat cgccgggtac agcggcgagg tggtgccgtg catcatgaac gcctcgttga
     2821 accgctcgtg cgcgacggga gcgcgtggtg agggcttgat gtgcaccatc gcggtctggg
     2881 acagcgcggc cagcagtttg tgggtggact gggtggcgaa caccgtcggc ctcgccgggt
     2941 cgtcgaacgt gtcgggtccg acggccatgc cgtaccggcc ctggtagagg ggatggaagc
     3001 gggcgtaggc gaaccatgcc tcgtcgaagt gcaggcgcgg cgtgctgggc gccagcgtcc
     3061 gtgccacctg gaccgtgtcg tagcacaggc cgtcgtacgt cgagttggtg acaaccgcgt
     3121 actgcgcctc gggcgtgagg gcaccggccg ccagcgggtg gccggcgatc cgcgcccgca
     3181 ccgcgtctcc gtcggtgcgg gcgggcggca gcgggccggc aaggccgtac ccgttgcgcg
     3241 tcgggaccag gtagacgggg cgagcgccgg agatcaccag gccgtgcagc acggacttgt
     3301 ggcagttgcg gtccaccagg gcgatctcgt cgcgcatcac gctgaagtgg ccgaccatgc
     3361 ggtccgcggt ggagtcgccg tggagcacga agtacgtgcg ctcggcgccg aagacgcggg
     3421 cggcgttgcg ttcggcctca ccgatggggc cgttgtgctc gaacagcgag cccagttccc
     3481 cgacggagat cgacaggtcc gtgcggaaca ggcgctcacc gtagtagtcg aagaacgccc
     3541 gtcccgccgc cgacttcagg aacgcgacgc caccggcgtg cgcgggggtg tgccacgagt
     3601 actggtgggc gtcgtcgaag cggcgcagtg ccttgaagaa cggcggcagt acgccgtcct
     3661 ggtactggcg cgcggcgccc gccacccgtc cggcgatgaa ggcggcggtg tcctccagcg
     3721 gccagacgta cccgcacacc acctcggcca cccacagcgg cagttgctcg aagtcaccgt
     3781 ccgtgtccga gcccgtcccg ccggtctccg tgtcctgcgg catcagcagg aacacgggca
     3841 ggtcggtgaa acgccgcccg atcgccgaca ggacctcggc cccgccgcct tccgcgccgg
     3901 cggggcccgg ccgcgggttc aggtcccagg ccaccagggc cccggcgagc cccgcctcgg
     3961 tgcgcagcac ggcctgcgcg tcgcgcgcgt cggccgccca ccgcacatgg aggccgcgct
     4021 cctccaactc cttcgcgatt ctcctcagtt gctccgcgac agccccgccg cccgcgttcg
     4081 tctcccgcgc cgccatcaga atcgttccgg tgctcatgac ctgcctcccc actcccggtc
     4141 acggatgtgt gccgagcggc taactggccg aggcaggcgg tgacaccggc tgccggacgg
     4201 gattcacccg atggggtaga gctcgggggt cctcccccac ccgcgacggg aggtgaatcc
     4261 gggacggaca cgggtggccc ggtgttgacc gccgcgtgcg cccgccctcg gggtgcgtgg
     4321 acggtcccta gactccccgc acatgtcgct ctggctgctc aaccacttca gcacgttcac
     4381 cctggccctg gtcaccgtcg gcgggacggt cgtcctggcc gtcgtcggca gcgtgctgct
     4441 gcgtcgccgg tacccgtccc tggccggggg cgagcacaac gacatggtgg gggtgaccct
     4501 ggggatgttc ggcgcgatct acgggatcat cctcgcgttc gtcatcgtca ccctgtggac
     4561 gcagctggac agcacgcaga ccgtcgtcgc gtccgaggcc accgacgtcg cgctgatctc
     4621 ccgggacgcc gccgcgttcc cgccgcccgt ccgcgcccgc gtcgacgacg cgctcggcgg
     4681 ctacctccac gcggtcgtgg aagtccagtg gccccgcatg cgcgcgggac agcccagcta
     4741 cggggccacc gccgacagac tgcagggcgt cttcgacacg ctccaggcgt acgagccgaa
     4801 gaccgcgcgc gaggaggtct tctacgagca ggccgtcgaa cgtctcaacg acgtcaccgg
     4861 gcagcgccgg gcccgcctga ccatggccga gcaggagctt cccccgctgc tgcagatcct
     4921 cgccttcggc ggcgcgctcg tcctcatccc gctcaccttc ctgtacggca tgcgccgcct
     4981 gcgcatccag cttctcttcg tcgcgtccgt ggccgcgctc gtcggcttca gcctgctgct
     5041 ggtgttcgtc ctggaccggc ccttcgccgg cgacctcagc gtgagtccgg ctccctacca
     5101 gcagggggcg ctcgcgcggt actggcacgg tgacctgccc gcggcggctg ccggcgatag
     5161 gtgactccgt cggcgcggag gccggcagtg ggccgtggct cgcggctcgc ggctcgcggc
     5221 tcgcggctcg tgggtcgacc gatgagttcg ggccgccggt cccgtctacc tctcgacgaa
     5281 aggagcgcac catgcgcaag atcatcgttt gcacgttcct gaccctggac ggcgtcatgc
     5341 aggccccggg cggcccggac gaggacaccg ggagcggctt cgagcacggg ggctggcaga
     5401 agccggtgtc cgacgacgag gtcggcgcgg ccatcgccgg ctggtacgac gtctccgacg
     5461 cgatgctgct cggccgcaag acgtacgaga tcttcgcgtc gtactggccg accgccgatc
     5521 cggccaaccc gttcaccgag cggatgaaca gcatgcagaa gtacgtggcg tcacggaccc
     5581 tgacgtccct ggagtggcag aactccacgc tgctggaagg cgatgtcacc gaggccgtac
     5641 gcgcgctgaa ggagtccgag ggcggcaaca tcaacgtcgt gggcagcggt gacctggccc
     5701 agaccctgat gcgcgacggc ctcgtcgacg agtatcgcct gaccatccac ccggtgatca
     5761 tcggctccgg caagcggctc ttcgccgacg gggcgatccc cacggccctg gagccggtca
     5821 gcgtcacggc gacgaagggc ggcaccgtcg tcggcgtcta ccggccgagc ggcaagcccg
     5881 gctacgacag ctactagaac gccacgcacg cctgcgaatg tcgagaacgg gccgccggca
     5941 ccgtccccgg tatgccggtg gcctcagagg ccgtgcaaca gagagggaga acttcatggc
     6001 gcttcagcgg atggacaacg tcggcatcgt cgtcgaggac ctggaggccg ccgtcgcctt
     6061 cttcaccgaa ctgggcatgg aggtcgaagg caaggcgcag atcgagggcc tcttcgcgga
     6121 ccaggcggtc gggctcgacg gagtgcgcag cgacatcgcg atgatgcgga ccccggacgg
     6181 ccacggcaag ctggagctgg cgcagtacca ctcccccgcg gcgctcggcg gcggagcgga
     6241 caacccgccg ccgaacacgc tgggcctgca ccgggtcatg ttcgccgtcg acgacatcga
     6301 cgacaccatc gcccgtctgc gccgccatgg ggccgaactc atcggcgagg tggcgcagta
     6361 cgaggacttc taccgcctgt gctacctccg gggcccctcg ggcatcctcc tcgccctagc
     6421 cgaacagatc agctgacgct ctaccctggt ctcgcccacc gttgtggccg gccgcctcac
     6481 caccttgagg ccgggtggag aggacgttcc cggcgggtag ggtcgggcaa tgcccgagtt
     6541 ggagccactg cacgccgatc acgcccccgc ggtcctcgcg ttcgagctgg cgaaccgcgc
     6601 ctacttcgcg gcctcggtcc ccgaccgtgg cgacgacttc ttcgaccggt tctccgagcg
     6661 gttcaacgcc ttgctggccg agcaggaggc cggcatctgt gccttccatg tgctcctcgg
     6721 tgaggacggc gcggtgctgg gcaggttcaa cctggtcgac atcgaagacg gcgctgcgga
     6781 cgtcggttac cgggtcgcac aacacgtctc cggtcgcggc gtggcgaccg cgaacgtccg
     6841 tgagctgtgc cggctggcgg cggtccggca cgggctgcac acactgcgcg cggccgttgc
     6901 cctgcagaat gccgcgtccc ggaaggtcct gctcaagtcc ggattcgtcc ccgtcggccc
     6961 ggccgacccg gcccacctca gcggcaagcc gggcacctgg tatcagaggc aacttgcctg
     7021 aaggacacgc cccctgcccg tcccctcagg ccgcgtcgag ggcatcggtg atcttgcgga
     7081 tcatgtcggt gacggcgggg ctcggggtgt ccttggtggg ccgggtggcg gtttccaggg
     7141 cgatcaggac ggtgctgcgg aagtcggcgg cccggtcctc gtcctgcttc ttcagcagcg
     7201 tcatcgtcga ggtcagggcc ggcaggacct cgtcggccat ggcggccgtg gtctttccct
     7261 tcaggaccac cttggacttc tcggcgagga cgtgcccgat cgggccggtc gcggaggcca
     7321 gtgcgatgct gccctgggtg gcgatccggt gcggggagtc ggcggcgccg gcggcggcga
     7381 gcagggagac ggcgccgtag gcggcggtgc gcagggtctg cttgtcctgg tcggtgaggg
     7441 tgagggacat ggtcggtgct ccttgggtcc gttgcgttcg gtgccttcgt tgtggaccgg
     7501 agcttgcgcc cgccgggttt caccgcggcc tcatctcggt ttcagaggcc cgcctgaccg
     7561 cgtcctccgg gccgggggcc gcgcgggcat cggcggccgg tgcctggtca gcggtccact
     7621 gcgggcaggt gggccaggcc ggtgtcgagc atgatgtggt cgatcgtctc gtgcagggcg
     7681 ctgtcggcgc cgatgacggt ctccacccca ccggggagca gatcgcgcgg gcggtaccag
     7741 tcgcgcagtt gcctcgcgtc gacgtcgtcg gcgatcggct tggtcgcgtg ccgggcgagg
     7801 gtttcgtcga acggcacgtc caggtagtag ccgtgggtcg ggccgcggtg gtcggcgcgc
     7861 agccgggcga gcatgtcgcc gtagcggtcg gcgtacagga tgccttcgac cacgacgtgg
     7921 aagccggcgt ccagcgcgta gcgggcggtc agctcgatca ggccgatgtt cgccgcgccg
     7981 ggccggtcgc gctcgcgcag cacgatgcgg cggaggttgt cctgggcgac gagggcgatg
     8041 ccgcggccga acctctcgcg gaggcctgcc gcgacggacg acttccccga ggcactgttg
     8101 ccgcgcagca cgatcaaccg ggtttccttg gtgcccacct tcacggcggt cacgttagcg
     8161 gctgccggtg acagcgactg gagcggagcg ggcagtggta ccgaccgccc gtgatgtctc
     8221 accccaggaa gggatcttcc accgtcggga tgtacgggga cagcagcggc tctgtgtgct
     8281 gggtgactct gcctcgagcg agcctgagga cacgcacgtc gttcccgtga cccggttcct
     8341 cgtcatcgtg aacatggagg agcccgtagg agccgggcgc gaccgcggcc acatgctcga
     8401 acagctggat gacgtccggc aaccggtgat tggagaagcc gccgaggtgg acgaacggtt
     8461 cgccgttcat ccacctgagg tcgagcaggt acgggctgtc catccgcgcg atgtgcaggc
     8521 ggagttcgtc gacgatctgc tgcagccggg gctcatcgtc gtcatcggcc gcggtctccc
     8581 tgacggtgat ccacccgtgg tactcgaaca tccggcgatc gtactcaggg cagcagcacc
     8641 gtccccaccg tcaggaccgc ggcatgatct gcacgccggc acgtcaccgg ccctgtgcct
     8701 cccgctcact ccccccgtgg ggctgcaggc aggtcctggg gcgcgctgtc gggctcgagc
     8761 atccgtgcgc cgggcacgct ctctcctgcg gacggccggg tcggcacacg gtcggatgta
     8821 tggcggatac acaggtgtgg gagtgcgtgg gccgcggtga cggcgctcgg tgtccgtacg
     8881 gggcggtgct gacgatcgac gcgggggtcg tggagtaccg atgcgacgac tgccgccact
     8941 actgggagct ggacgagacc gagccggagc ggcgggcgac agccgaggac ggactgaccc
     9001 tgccggtggg cgacccgcga gaggccggtc ccggagcagc cgcgtagggc agggggccac
     9061 gtgcattcaa gaactgtccg aggccttccg tcccgtcagt ccctcagccc gtagaacccg
     9121 atccgcgagt tcggccggaa gccgatgcgg gggtacacgg gagccccggc gaccgtcgcg
     9181 tgcagggtgg cccgggtcag ccccgtggcc tgtgcgcctt cgtgcagcgc cttgcgggtg
     9241 acggcctcgc cgtaacccct gcgctgccac tgcgggtccg tggcgacgag tgcgacgaac
     9301 aggcggccgt ccgccgggat cgctccggcg cacgccacgg gctcgccgtc ccgcagggcc
     9361 aggtaggcgt ggacctcctc cttccacaga gcggatccga ccagtccatc gcggcctgcc
     9421 tccagcggga aaccgtagcc gcgcgagttg aggtcggcgt aggcgcgcac ctgctcgtcg
     9481 gtggtcacgc gcacgaacgt caggtccggg tgtacggggt ccgcgagcgg gagcaggtcg
     9541 ccggccatgc ccgtcccggg gaaggcgtac tgcaggcccg cctgctcggc cgcggtctcg
     9601 agcgtggcgc gggcgtcctc gtcgagcagg tcctcgaaca cccacaggaa gcccggctgc
     9661 cgcttggagc gcatgatctc cgccgccttg gccagacgct cgccgaggag ccgcgcgtcg
     9721 gcgcccacgt cggtgagggt gagggcgttc cagaaggcga accggcagtc ggcccagcgg
     9781 acggcgatgc cgggcaggtc ccgcacatcg gcgtccgcgt cccggtcgag caccatggac
     9841 cgccagacca gggccagttg ctccatcgat tcgaccgact cggcgagatc gctcatcgtg
     9901 actccatgac ttcgtggcgt ccacacgacg cgctgtcgtg acgggtggct ggagccacga
     9961 tctttcacgc cggaccggat caccgagacc atttccggtc tcagtccacc gtgatgaacc
    10021 tctggaagta ctccgcgggt gcgccctccc cgaccagcac cccttccgcc tccacccacg
    10081 cgtgcgcggc gaacggcggc tgggtgcgca ccccgacgca ccaggtcggc cactggccgc
    10141 gcagccggca cagcagcacg gtggccagtg accggggcag gcagccctgc tggccgccgg
    10201 cggccaggct gacggcgagg accgtctcgc gggcgcgggc cgcctcggcg gctgtcgcgg
    10261 gcctggctcc ccgacgcagc cggagcagca ccgcacggat gcgggtcggc ggctggcggg
    10321 cgagcagatg ggcgcagccg acggccagcc gggtcaccag ccgcgggccg aggggcaccg
    10381 agcgggggtc gtgcgggacg acttgcgagg tggacactgc ggcaatccct ccggtacgga
    10441 gaaaaggtgc ggacagagag ggcggggtta cggacgtgac acgacgcggc gaccggccgg
    10501 cgtccgctgg cccggtcggc cggtcggccg ccggtcagcc ggtcgcccgg tcagccggtc
    10561 gccccttacg acgccagaag cctggcggcc cgcagctcct ccaggatgcg ggtgatgtcc
    10621 tcctccacct gctcgctgct cacggcgtac cggccggtga gttcggccac cgtctcctcg
    10681 ctgctcgaac cggcgagcag ggtccgcacg atcagcgccg cggtgggatt gagggtgaag
    10741 tactcgccgc tgttctggtc gagcagggcc atgccgtact cggtgtcggc cgtcaccacg
    10801 ccggggcgca ggcgcatcgt catgtcgggg tacctcctgt gtcggttcgc gtcggccgcg
    10861 gcgggccgtg gtgtcgttcg cgtgcgcgca gccagacctc gcagccgacg gtcgggtgca
    10921 gcagcgcgct ctccaggtcg gcggcgagcg ggcggaggca ccagtcgcgc aggggcgcca
    10981 cgtcgacgag gcccagctcg cgcagccggg agtcctccca gagggcgagg agtgcggagc
    11041 ggtggcggcg caggccggtc tcctcctcga aggcggcgtg cgccttggtg gtgcgggtgc
    11101 ggccggcctc ggggacgaca ccccgcatgg cctcctcgat cagcggtttg taccgccagg
    11161 gcgtgatgcg gtcctggggg cgtacggcga aggcggcctc gacgaggaga tcgtcgtagt
    11221 agggcgcggc gaacgtgacg ccgagcggtt cggacatctg ctggacgtgg cgggcgaagc
    11281 gggccagggt ccgcagcgtg gcgatctcgc ggtggccgcc gtggcccggg gcgagcggcc
    11341 gtacgtcctc ggcctgttcg tggatgaggt cccgtaccgc ctcgacggcc cgggcggtgg
    11401 cccacggggg cagccggggc ggggtgcccc aggtgaacag ggggacggac atggggggtt
    11461 gggggtacgt gaggtcgcgg gcgacctcgg ccagccagga gccgtacggg cggcggtcga
    11521 ggagctgggc cagggccgtg cggcgggacc agcggtgccg ggaggtgaag ccgcgggcca
    11581 gtcgccaggc cgtacggggg tggcggggca gcagtccgtg gacgtgtgca ctggcgccgc
    11641 tgaacagttc gtcgccgccc atgccgctca ggtgcagcgg ggagccgcgt tcggcggccc
    11701 gctcgacgat gtacatgcgc cggtggcggt tgaccgcgta gagcgacggg atgtcgaggt
    11761 cgtcgtcgag cgcgtcgacg cggtcgaagg tcaggggcac ggccggggcg ggtacgacgt
    11821 ggtgctccac cccgtccagc tccgccaccg tgcggcgggc gtaggtgacg tcgtcgccga
    11881 ggacgtcgtg gacggcggcg gtgtaggcga cggtcttggc cccggcgcgg gcggcggtgg
    11941 cgaccaccgc ggtggagtcg acgccgccga ggtcggcgct gatcagttcc cgtccggtga
    12001 cgcgtacggc gaccgcgtcg gcgagccgtt cgcggaccag ccgggcccct tccgcgagcg
    12061 gcagttcggc ggagggcggg ctccagcagt gttctgtgcg cagccgcccg tcgcggtcga
    12121 ggaggacgcg ccggtcgccg gggacgacgt cgacgccgtg ccagaccgtc tgcgtggtca
    12181 gcgggtgcag gatcccgggg ctcagcaggt gcacggccag gcgtccctcg tccaggtccg
    12241 cgcccgtcag gtcggccagg acgtcggcgc ggtcggacac gaggtgggcg ccgtgggcgc
    12301 cggggacccg ggcggtgaag aggctgcgga cgccggtgac ggtgccgtgg accagggtcc
    12361 tgccgtcgag ggcggcgatc aggtggtggc tcccgggcca ggtccgcgcg acggcgtcgg
    12421 cggcgcgggg tgatccggcg cgagcggcgc ggtcggcctg ctcctgcgtc acggcgtgct
    12481 gcccgagcac cgccagccgg gcaggtccgt gtgccgcggt ccgcgcggcg tggtcgggcc
    12541 agcggccgat cagccagggc cggccggagg ggtgcgggat ccgccgggtc cccggggcac
    12601 cggctcgcgc ggcgaggtcc gcgacggcgt cggtgtccgg gaagacgacg aaccagctgg
    12661 cctcgggcgg atgcgacgcc ccggtcgcca tgggcgggtc cttccggtcg gggtgcggtc
    12721 ggtggtgtgc accatgggcg tgggcggtac cggcggtacc gcccacgctc ccaccccgcc
    12781 cagtgattac atgtacatga caatcacggg gcggggcgga gaagaggtca gagcaggctg
    12841 tggccgccca gcaggtcggg gctgccggtg ccggccaggc ccgtgacctt ctggaagtcg
    12901 ccgaccttcg tgagcgtggg acgctcgtaa gccatcgtcg tatcccttcg tcgattgaac
    12961 gcttctgaga ggaacccgct gcagcggaag gcgggtcgcc ccgcccggtt cccgcgccgg
    13021 cccgccgctc cgagtggacg gggcgccggc gcggttcacc aagctaggag ccgcctcccc
    13081 gcctcacaac ggggtccgtc ggccatccgg gccgtagcgg cgcatcgccc caccggcctc
    13141 gtacgcctca ccgctcacac ttttccgacg acgagtcatg cttcccgtgc gcgggggtac
    13201 tcaccatgcc ctccccgcag ccacacgacg tgtttcggcc ccgtccaccg cgagccggac
    13261 cggcggactt cccgcggaac accgccgtca gctcgtacga cgcggcaccg gcaggccgcc
    13321 tcggcgacaa gggtcggcca aacggcgccc ggctggccgg gagttcctcc ttgccggacc
    13381 gggccgtcgc acgcggggga agaccccgcc cgcctggacc tcgcggcccg ccgggtcagc
    13441 gcgcgggccg gtcggggatc gcggggagga ccttctccgc gatcttgagg agcgcgctgt
    13501 cgtccggcag caggccggac tggctccaca cggtgatgtc gtagtagccg cccccgtccc
    13561 ccctgtcgag ggccacggtc agcgtcctgg ccagggggcc ctgctcgacc gggccgcccg
    13621 acgcgctgcc gccgagatcg atgctgatct tcatggtgtg gtccgaggag agcaccgcgg
    13681 gtctgcggtc gaggaccttg agcgtcctga cgtcctgctc gctgccgtac ttcatcagct
    13741 tcacgtactg ggcgaccgag aggtggttgt acgtcgccgt gacgttcacc gtgtacgtgt
    13801 cgaacgtgac ctcggcttcg ggctgggcca ctttcccgtc ggtcagcggg gcggtgttgt
    13861 tggtggcgct cgccgcggtc gccttctccg tcggcgtgcc gaggagctgg gccagagcgg
    13921 ggctgttgag cagcttgcac agttcgtccc cggtcaccgc cctcggcgtg tccctgaacg
    13981 ccttcggcaa ctcctccttg cccgcctcgg ggcacgagac ggaccgcggg gtggtgtcct
    14041 cggacggcaa cagccgcggg cccgcccaca ggacgcccgc gatcagcgcg aacacgccta
    14101 tggccgctgc cgcctggccc catgcgttgg gttccttctc ggcggcgggc ttctgggtgg
    14161 aggcaggcgc cggagcctcc accggtacgt gcgtctggac aggaccctgc tgctgtacgg
    14221 cggtcccctg ctggaccgcg ggctgcggct gggcggcgac cgccggggcc gcggcctgca
    14281 ccgggaccgg ggcctgcgcc gaggtcgacg cctgcgccgg cgcctggatg ggggcggcgg
    14341 catccgtcgc cagagccccc tgcgcgacgg ccgccgcgcc cgccccgcgc cgagcgcgcc
    14401 acgcccggac cacgccgtgc acacggaccg ccgtgaacac gaggaacacc gcgccgatgg
    14461 cggcgggcgt ccagtcctga tcgcggacgg cgagatacat gatgcgcacg ccgaaaacgg
    14521 atccgaccac gatcagaagc ggctcacgca cccagaaggg caggagccgg acgaggaaac
    14581 cgagcatccg gtgatctcac caggtgcggg ggctcgtacg ccgtggtgga agccacagtt
    14641 ccgccgccaa tatgatcaac agcgatcgag gagtgcgact gagtcacacg gctagggctt
    14701 tcctccggtg atctgcgcgt cgccccagga gccgtagtag acgcttgagg cgtcctgacc
    14761 ggtgtaggag acggtcagtt tgagtcgcag ggcgttgcgg atgtccagcc tgacctcgcg
    14821 tgacgcgccg agacggatgg tctcccggaa tctgcgcgtc ccgtcgaccg ccacctcgaa
    14881 ggtcaggctt ccgccggtgg gtgagtcgtc gcgcagtccg gccgtggcgg tgaaggtggt
    14941 ccagtggcgg ccgaggttgt attcggcgga attgaccggg ccggcggcgt tgcaggccag
    15001 cgtgacgctg ctggcgaagc ctgtcccgtt gatctcggcc gtgccggtgt cgatgccctc
    15061 ggtcgccgtc agcggatcca gttcgttgag gtagcggctc tgtgcggact cgccggtggt
    15121 ctcggaggtg ccgcccgcgg tgaccgtcac ggtcggggcg gtcgcggtga ccgtgcgcgt
    15181 ggggccgggc ccggacgttc cgcctccgca cgcgccgccc agggtgatcg ccgctgccgt
    15241 cacggcacac gccgccacgg ctctcgcccg gctcaccggt cggggccttc acgcgggagg
    15301 tccggtggat ggtccggggg tggcgggtaa cgcggcggat cggtgtccgg aggcgtcggg
    15361 taacgcggct gatcgctgtc cgcgagcgtc tcgtgcgggg tctgcttccg cggcccgaag
    15421 cccggatacg ccggcgcttc gcccgttccc catcgagaaa ccagggtgta gatcacgaac
    15481 atctcggtca cgagggcgaa gacgaacccc agccacagac cgacaccggt gccgaccttc
    15541 tcgtccgtga aggagcccgc cagccggttg tacgcgtcgg ccagttccga gacgtccgcg
    15601 accttcacca cgtacagggc cagaaggacg gaggagggca ccaacgccag tctcacgaac
    15661 cgcctgtcgg ccgtcgtgac ggcgacggcc agcgacgcga tggtggcgac ggccatcacg
    15721 atgatcaggg ccggccccgc cgcctgcagg gcgtcgccga acgcgttctg gctgtcgtcc
    15781 ccgctggaca gccagggagg gaagagcatg acgaagctca ggagagccga gaccgctgcc
    15841 gcgagcagtg gccagtcccg tgcgacctcc aggcggtgcc ggtgccgcgg aagacgagcg
    15901 gagatcgtca tgcgtcctcc cgggaggtgg acgacatccc cgtggcgcac ccggtgccgg
    15961 acgcgccacg ggcagtctgc cggtcattcc accatggcct gtgcgaggtg ccgtcgcacc
    16021 ttgtgatcgc ctggaggtgt cgctcagagc tccggcacgt agtacggctg caccgtcatc
    16081 cacccgttgc cccgggcgcc gtggcgcgtg ccgttgtcac cgcgggccag cgtgtaccag
    16141 gagtcgacgt agtccgggtc gtcggtccac cagtcggccg ggatggcgtc gaggaccgcg
    16201 ttcaccagcg ggatgtaggc gccctggtcg gtgatggtga gcaacgcggc ggcgatggcc
    16261 tgggcgaggt cgtggtagtt ggtgctgccg tcctcctcca tcatcacggc gtcggccagg
    16321 tcgtacttgt acgaggacca gttgaccagg atctggttcg ggcggtagac ggtgccgtcg
    16381 ttgtcgaggt acggcatgtc gacggggtcg acgcgcacct tgccgtcctg gccgaagccg
    16441 gtgacgaggg tgtagatctc ggcgtcgccc ttgatccacg gttcctcgtc gtcggacagc
    16501 tcgaccgcgg tgatccgggt ggtccagaag ccgccggtgg ccgcgagcgc cggcgagcgg
    16561 tggccggtgg agggctcggt gccggtccgg gcggccgcgg cggtcggctc ggcggaatgg
    16621 acgccgtacc gtgcgagttc cccggtcagg acgtccagcc cggcggccag tgccgtggag
    16681 ctgtcgatgt cgacgacgta caccgggtgc gcgggcgcct tgcgggcgtc gagggtgtgg
    16741 gccctgccgt ggctgtcgta ggcggtgacg gtggtggcgt cctcgtcctg ggtggccgcc
    16801 gcaacccagg gcgtggtccc ggcggtgagc gcgccgcgca tggacgcgtc cccgagccgc
    16861 aggcgcagca gcgggccgac ctcggcgccc aggcctttcg ccgtggcgat ccgccggtcg
    16921 gccgcggtca gggtggagcg gagggcgcgg ctgccgccgg cttgtgcggc cagagcggtg
    16981 acgtccacct cctcggaggc gagcgcggcc gtgcggacgc gggcgcgcca gacggagtcg
    17041 gtgagggagc cggccatggc ccgggcggcc tggtcctcgg ccgcggtgac ggcggacgtg
    17101 ggggcggggg cggtggtggc cgccgtggcc ggcagggcgg tcagggtctg gccggcgcac
    17161 agggcgacca gggctgccgc ggcggcgccg aggccgcgcc ggcggaggtg acggggtctc
    17221 acggggatcg gtcctcctgg ggcgagtggt cggtgtcgca ctgtcaggtg gagcacgagg
    17281 cacgcatcta tgcgggtaga cagacgcgtg cggatccaga atgacggtga catgacaccc
    17341 agacaagacc tgacgacacg gcgagcggac gattgccttg ggcgtctccg ggcagccggg
    17401 tcagcagggg cccggaggcg agcgggaggc tgatctcgat gactgtggcg acgcaacagg
    17461 gtggcggagg ctccagcggc ctctacgacg tgctcgaact gatcctggac cgaggactgg
    17521 tgatcgacgc gttcgtccgc gtctcactgg tcggcatcga gatcctcaag atcgatatcc
    17581 ggatcgtggt cgccagtgtc gacacgtatc tgcggttcgc cgaggcctgc aaccgcctgg
    17641 acctcgaagc gggcccgcgc aagcccgccg ggatcaccga gctgccgggc aagctgacgg
    17701 agtccggggc gcgcggcaag acgaagggcg ccttgtccgg tgccgcgcag gccgtcgccg
    17761 acgcctttca gcaggggcgg gacgagggac ggaagtagga ggcgcgccgg gccgcctggg
    17821 tgcgcaccgg tccgccgggg ctcgcggcgc ggcgcaggcg ctcaggcctc gcccgcgtgc
    17881 gtgtccggtc cgcccggggg tacccacagc cctgccgagc ggcacgtggg agcgctggtg
    17941 ccgtgtcgat ccggtgccgt gccgtccggc ggacgggacg agggagcggc cgatgaccgg
    18001 cgagagaccg ccgaagcggc ggacgaggcg cctgcgggcg acggcagccg aggtcttcgg
    18061 ctgggacgaa ctgcgccccg cgcagctcac cgccatggaa tgggtgctgg agggccgcga
    18121 caccctcgtc gtcatgccga ccgggtccgg caagtccgcc gtgtaccagg tgccggccct
    18181 gctgctgtcc ggcccggtgg tcgtcgtctc cccgctgctg gctctgcaac gggaccagat
    18241 cgcgggcctg ccgggcggcg acgacgggcc aggcgcagtc gccgtgaact ccgacctcgg
    18301 tgtggccgag acggaagccg cctgggacgc cgtacgcagc ggtgccgttc gcttcgtcta
    18361 tctctccccc gagcagctgg ccaaggacga ggtggtgcgg cggctggccg aggcggagcc
    18421 cgccctgttc gtcgtggacg aggcccagtg cgtgtcgtcc tggggccatg acttccggcc
    18481 ggactacctg cggctggcgc aggcggtacg gcggctgggg cggccccccg tcctcgcgct
    18541 caccgcgacc gccgcgccgc cggtccggca ggacatcgtc gaacggctcg gcatggactc
    18601 cccgcggcac ctcgtcaccg gcttcgaccg gcccaacatc cggctggagg cacaccggca
    18661 cctcgacgac gcggaacggc ggcgcgcggt cgtcgagcag gccgccgccg ggcccaaacc
    18721 ggggatcgtc tacgccgcca cccgcaagga ctgcgagttc tacgccggtg aactggccgc
    18781 tctcgggctc gccgccgagc cgtaccacgc gggcgtgcgc gccgccgagc gcaagcggat
    18841 ccacgaggcg ttcctggccg gggagaccga cgttgtggtg gcgacgtcgg cgttcgggat
    18901 gggcatcgac aaggaggacg tgcggtacgt gctgcacgcc tccctgccgg gttcgctgga
    18961 cgcctactac caggagatcg gccggtgcgg ccgggacggg cggcccgctc tcgccctcct
    19021 gcactaccgg tcggaggaca cggggatgca ggtctacttc agcggtcgcc ccccgagcag
    19081 gggcaccgtg gacacggtgg tgcgggccgt gcacgaccac cgtgacgacc cggtgcgcct
    19141 ggacgggctg cggcgcgaga ccggcctgtc ccgcacacgc ctcaccacgg ccgtcaacct
    19201 cctggaggag gccggcgcgg tcgagacgga cacctccggc gccgtccgcc cctcccccgg
    19261 cacctccccg gaggccgcgg tggaacgagc agcggacagc gccgaggcgc accggcgcat
    19321 ggaccggtcg agggtggaca tggcccgggc ctacgcggag acgaccggct gccggcgccg
    19381 cttcctgctg ggctacttcg gcgaggagta cgcggaaccg tgcggcaact gcgacatctg
    19441 cgacgcgggg gcggccgagg acggcgatgc cccggccgcc gggcagcgtc ccgcccatcc
    19501 ggacgcgggc tcctacccgg tcggggcggc cgtgctgcac gaccagtggg gacgcggcac
    19561 ggtgctcagc gaggacgcgg accgcatcac cgtcctcttc gacgacgtgg gctatcgcac
    19621 gctctccctc gacgcgctgg ccgaccggaa cgacctgctg acggtggccg acgtgccgta
    19681 gccggtacac ctggcgcggc cctctccgtg ccgggcccgg gccacgtcgc gggtcagtgc
    19741 ggcgccggac gtcgctcggt ggagtgctga tttcgcgcag aggactccat gccgcaccga
    19801 cgagggtgtg taatcacgtg ggtccggacg ggcggggcga agagggggac aacgggtgga
    19861 cgagctgcag ccgaccgatc cacggcaggt cggccggtac cggatcaccg cgcggctggg
    19921 cgcgggcggc atgggccgtg tctatctggg ccgctcgccc agcgggcggc tcgtcgcggt
    19981 gaaggtcgta cggccggaac tggccgacga ccccgacttc cgccgcagat tcgcccggga
    20041 ggtggccgcg gcccggaagg tcaccggctt cttcacggca gcgctggtcg acgccgaccc
    20101 cgacggcccc tctccgtggc tggccaccgc gtacgttccc ggcatgcccc tggacacagc
    20161 ggtcgccgtg cacggcccgt ggccggtggc gtcggtcagg acgctggggg ccggtctggc
    20221 cgaggccctg gaggcggtcc acgcggccgg tctggtccac cgggacctca agccctccaa
    20281 cgtcctgatc gccgcggacg gcccccgggt cgtcgatttc ggcatctccg tggcggccga
    20341 ggccaccgcg ctcacccgga ccgggatcgt cgtgggcacc ccgggcttca tggcccccga
    20401 acagctgacg ggcaagcccg tcacacccgc caccgacgtg ttcgccctgg gcgcggtgct
    20461 gacctacgcg gccaccggca ccggcccgtt cggcaccggc tcggcccagt cgctcaactt
    20521 ccggatcgtc tacgaggaac cggacctgtc cggcctgccg tcgcccggcc tggagatcgt
    20581 cgcccgctgc ctggccaagg accccgccca ccggccgtcc gtgaccgcgc tcgtcgaaga
    20641 actcgccctg ccggcaccgg atgccgacgc tcccccgccc acggggtccg acctcgccga
    20701 tacggcctgg ctgcccggcc cggtcgcgct cgcgctgccc gccaccgtcc ccgcctcccg
    20761 ccggcccctc ccgccccggc ccgcgacccc ggcgcctgta acacctgagc ccgggcccgc
    20821 gtcccccgtt cctcccgccc cggcgccgat cccgccgcgc ccacgggccg cgccggtcgt
    20881 caccccgcct ccccaggcac gccgccgcag cgtcctcccg ctctggatcg ccatggcgtc
    20941 actggcactc ggcgtggtcc ttcccttcgt cgaaggcgac atcatcgtca ccagcctgga
    21001 ccatggcgcc tggccgttcg tcgtggtcgt gcttctcagt atggccacct gtgttgcggc
    21061 cctggtcgtg cggcggcgtg ccaccgcgag tcgcggtccg ctctgggtgc gcatcgtgca
    21121 caccgtcacc accacgctca ccaccgggtt gttcgcggct ctgctgtcct cccagtacgc
    21181 ccgccagggc aaactcgacc aactcgatgt gggggcctgc ttcttcggac tcgggtgcct
    21241 ggcgctgctc tacagcgtct tccggttccc cgcgtccagg cggagacccg cgccctgaga
    21301 ggctcagggg aggatggcgt cgacgtagcc gccgtccacg cgcagcgcgc cgcccgtcgt
    21361 ggcggacgcc tggtcggagc tgaggtagac gaccatgtgg gcgatctcct ccggttcgat
    21421 cagccgctgc agcagggact gcggacggtg ctcgcgcatg aaggcccgct gggcctcgtc
    21481 ccagggcagg gagcggtcga cgagttcgta gacgaagtcc tccactcccc cggtgtgggt
    21541 gggcccggcg aggacggagt tgacggtgac gccggtgccg gcggccttct tggcgaagcc
    21601 ccggctcacc gcgaggagcg acgtcttggt catgccgtag tggatcatct cggccgggac
    21661 gaccaccgcc gagtcgctgg cgatgtactg gatgcgcccc cagccgcgct ccatcatccc
    21721 gggcaggaac atccgggtga gccgcaccgc ggccaggacg ttgacctcga agtagcgccg
    21781 ccactcggcg tcgctgatct ccagggcgtc tgccgagccg aagacaccca ggttgttgac
    21841 gaggacgtcc acgtccggca gggactgcgc gagccggtcg gcgccctcgg ccgtgctgac
    21901 gtcggccgcc gcggggacga ggtcggcacc gggcacttcc ccgcgcaggc ggtcgacggc
    21961 ctcccgtacg cgctcctcgc tgcggccgtt gacggcgacc cgcgctcccg cccgggccag
    22021 ccccgccgcg atggccgcgc cgatgccctg cgtggagccg gtgaccaggg ccgtccggcc
    22081 cgtcaggtcg atctgcatgc gctggacctc ttcccgctac tcggtgcctt tcggctcacc
    22141 gttcccacgg gcggcgcgtt gtcaccggtc cggcggcgaa gagtcacacc ggcggcgtcg
    22201 tgcgcgggcg ccatcgtcgc ttccgttcgg gggcgctgcg gtggcggccg acggggcctg
    22261 cggccaggct ggaggcgaac ctgggaggac cttgtgaccg cttcgccgcc cgccgccccc
    22321 gacgccccgc cggcccggta cgacgacctg agggccatgg tgatcaactg caccctcaag
    22381 cgttccccgg agaccagcaa cacgcagggc ctgatcgacc gcagcaccac catcctggcc
    22441 gcccaggggg tgcgggtgga cgtcgtacgg gccgtcgacc acgacatcgc caccggggtc
    22501 tggcccgaca tgcgcgagca cggctgggag acggacgcct ggccggagct gtaccggcgg
    22561 gtcatggcgg cggacatcct cgtcctggcc gggccgatct ggctgggcga caacagctcc
    22621 gtcatgaagc aggtgatcga gcgcctctac gcctgctcca gcctgctcaa cgacgccggg
    22681 cagtatgcct actacggacg cgtcgggggc tgtctgatca ccggcaacga ggacggtgtc
    22741 aagcactgcg ccatgaacgt gctctacagc ctgcagcacc tcgggtacac gatccccccg
    22801 caggcggacg ccgggtggat cggcgaagcg ggaccgggcc cgtcctacct cgatcccgga
    22861 tcgggcggtc cggagaacga cttcaccaac cgcaacacca ccttcatgac gtggaacctg
    22921 ctgcatctgg cgcgggccct gaaggacctc ggggggatcc cggcctacgg caaccagcgc
    22981 accgcctggg acgccggctg ccgccacgac tacgagaacc ccgaacaccg gtagacaccg
    23041 gcggcgtggc gcggaccagg atcccgaccc ggcacgcaaa acggctggcg ggtccggggc
    23101 ggtggttgcg agcatgcggg gcatgaacac cgccgaagac gccctgatcg acgtagtgcc
    23161 gctcggtacg gcgcccgtgc cggagcgggg ccgggtcgag gcgctcgccg gcggggggct
    23221 cgtcgtccgc gcgcccgggc tggtggaggt gcacgaccgc gaggacttcc tcgccggagg
    23281 ggcggcgggc gcgcgggccg ccctgcggac gcgggagccg gaacgggcgg tccccacgcc
    23341 ggacggcggg ttcgtggtgg ccggggtgtc gtcggtgcgg gcgctggacg ccgacggcgg
    23401 cacgcgctgg gaactcggcc acgaccggtg gcacggcgcc gaccgggccc attccgttcc
    23461 cgccgtgagc ccggacggac gcctggtgag cgtcgtcgta ccgcgactgg agcccgagaa
    23521 ggagaaggcg gctctggtgt acgacctgga gccgggccgc aactacacct gggacgagct
    23581 gcttctgctg gacgcggcga ccggtgcggt gctcggccgg cggcagatcc gttcgctggc
    23641 gtcggccgcg gtcgcctcct gggggccgga cggtgacgcg gtggtggtgt cctgctggac
    23701 cgcctggcag agctggtcga cctggtgggc cgagccgcgc gcggacggtc cgcacctggc
    23761 cggcgcgacg tggatgcacg cgctggcggg cttcctccct ggcggccgga tgctgacgca
    23821 gcggtacgcc gagtacctgt tccccgacga cgaccgcgac gagctggcgg tgtacgacct
    23881 ccgctccggc gaacaggcgg cgctggtgga tctgagggaa ctggccgtcg acccggagaa
    23941 cgacgagttc ctctccgccg aggtcctgga cgggcggcat gtgctggtgc cgggacgggt
    24001 gcacccggcc cccggggtgg cggagctacg gcactggctg ctcgacgcgg gcacgctgcg
    24061 tccgctgggg cggctgaact atccggtccc ggtgggcgag gacgtcaccg cgctgcggga
    24121 cggcacctgg ctcacccggg acggcaatcg actgcaccgc tgggcgctgg ggcactccgg
    24181 acccggcggc gtcgacgccc gctgagtcgg gtcgggggac gtcgcgggcg gtccggctca
    24241 gccgatctcg acggacgttc ccgcggtcag gtggcggtat ggggccccgg tgccggggcc
    24301 gttgtcgccg aggaggccgc cgaccatcgc ggtgccgatg tcgttcaggg cgccgtcgtg
    24361 gatggcgtag gaccgctgcg gggccaccgc gcgtacatag tcaacgagtt ggccggtcgt
    24421 ggaccacggc ccgtgcaccg gcagcagcag ggtgtcgacc gcggtgtccg ggacggtgag
    24481 ggcgtctccg gggtggaaca gggcggcgtc gacgaggaag ccgatgttcc cgacgcgggg
    24541 gatgtcgggg tgtatgacgg cgtgccaggt gccgtagacc cgcacgtcga agccggccgc
    24601 ggtgaaggca tctccctcgc cgacggcggt cacccgcccg cctaggccgt ccagccgccc
    24661 ggcgacggag gtgttggtcc agatccgcag ggccgggtcg cgctcggcgg ccgcgcgcag
    24721 cgtctcctcg gaaaagtggt cggcgtgttc gtgggtgacg aggacggcgt cggcgccttc
    24781 cagtgcccgc gggtcggtca ggccgcccgg gtcgacgacc agacggcggc cgtccttctc
    24841 gacgcgtacg caggcatggc cgaacttggt gagacgcatg gcggttcccc ggtcctctcg
    24901 tggctccaca gcccgaaact gtacatcttg gttgtacatc tagattacac agtcccggta
    24961 ggatggaggc catggacgac gacgtgctgg ccgaagacct gcggcaggtg atcggggaac
    25021 tggtccgcgc cgtacgcgcc gtggacacca tgccctccgg agaggccgcg accctcggat
    25081 acctcgaccg cagcggcccg ctgaccgcgg ccgacctcgc cgcgctgcgc cgcgtgaccc
    25141 accaggcagc caccaagtcc gcgaaggaac tcctcgccga cggcctggtg cgcgccgagc
    25201 cccaccccac ggacggccgc aagcagctgc tgcacatcac cgacagcggc cgcgcccgcc
    25261 tccagcggga gcgggcacag cgcgccaact ggctcaacgc cgccatccac gaggccctga
    25321 gcgccgaaga gcagcgtcaa ctccgccagt gcgtagggtt gttggagcga ctgaccgccc
    25381 acatcacggg gcggtgacct cgcccgaggt cacggccggg ccgatcctga agcggaagtc
    25441 ggccagggag acggccgcga cggggcggtg gccggtcagg taggccagcg ggccctccgg
    25501 gtggacgcgg gtgcggatgc ggctgaggga gggacggccc gtcaggcgga gcggcacccg
    25561 gcaggtggtg ccgtcggctc ggggctgcag gaggtgtgcc cggacgggca gccggagggg
    25621 aaggcggagc aggtcccggc acagcgccac cgcgtccggt tcgcgccgcc cggcagcctc
    25681 cacggtcatg gtggtccgca ctccccggcg cggggacggg tcgggaggca ggggccggaa
    25741 gtcgaaggcg gccggttctt tggggatggc ccacaggtgc cgcccgccgg ccagggagcg
    25801 ctcgtcgtcc acccacacct gcaccgccgt ggccgcgagc ccggctccct gccgtacgac
    25861 gaccgccacg agcagttccc ggtaggcgag gtccccgccg tccccgtagt ccacccagaa
    25921 ggtgatcagc ggagtccgtc cggcgagcga caccgcccgg gcgccctcgg gcaggggcca
    25981 gggcgggagg ccgtaccggg gcacgagcca caacgcggcc cgcatgtcgc cgcgcagatg
    26041 ccacggctcc ggaggatggg gaggacggga agggggcatc gtcaccggcc ttcggtcgaa
    26101 gcgatcaccg cgtcggggga cgggggcggg cggtctgctc gtcagtgtcg taccggcccg
    26161 cttccctcgc catggcggtc cactcccccg ccgacgcggc ggcccgcgca ccctgtcagc
    26221 gcggagcgac cgtcggagcg ggtggcgccc agcgctgcgt acggggcacg ccgcccgcga
    26281 cgccgaagtc cttcttcagc tcctcgggga tggcgtagtg catgacgcgg ccgcgcgtga
    26341 gggaggacag ctcgaagacc gtggtgaggt ggccgaggcg gtccagcgcc caggcgccca
    26401 gcggcgagcg gtcctcgatc gtctccagga cccccagcag gcccggcacc accttgacca
    26461 cgctgtccca ggtggtacgc gggacccgga gccagtcggc acaggtgtcg ccgatgaggt
    26521 agcggatcag ggcggagacg accgggtcga agaaggtgcc ggggacgacc tcctcgtaca
    26581 ggtcgatgag ctgccgcgtc aggtggacgc cctcctcgga cggccccatg tggcggacca
    26641 tgtacaggtc gaggaactcc cgggcctcct ccagcgtctt cggtacggcg tcctggtcga
    26701 caccgaggat cgcgccgacc acccgccagg cgtagaagta ggcctcggca ccctcgacgc
    26761 tcatgtggat gcccagccgg tgcaggctgt ccagcaccag cagcgagaag aacatctgcc
    26821 cgccgatcat gtcctcctgg cagatcggcg tcccgagcgt cccggtgtcc cagcggtcct
    26881 cgcgctgaag gtgatgccgg atggaggcgt gcagcaggcg caccttctgc gcggcgggga
    26941 ggaacctgcc gccggcctcg aacgcgtccg gccgcatgag gtggacggtg aactgcccgg
    27001 tctccgccat gcgcttcgac ggatagtcca ggccgtgcgt ggccgacagc agccgcgcca
    27061 cgtgcgggac gacatagcag gcgggcatgg aggcgaagga cagggcggtg gagatgtgca
    27121 cgttgttgtc gaggaagaac agccgggcct tctccatctc gccccagtcc acccaggacg
    27181 gcggtacgcc ggtcgtgtgc aggtactcgc gggcgacgtc gggcaggccg tccggcaggg
    27241 gtgcgccggc cgtcgagacg tagcgcatca gggtgttgaa cttgcccacc tcgccgcgct
    27301 cgaagagggt ggcgacgacc gcgtcggcga gttcgtcacc ggactggcgc agggcgtcca
    27361 tggaggcttc ggtgaaggtc atgacggcgg tccttctcgg gtggttgggg ggtggcgcac
    27421 cgtcgcgaca cggtcggtgc ggtgcgtggt cagtggtggc ggtccgtcgc cgagtgcgcg
    27481 aggtcggtca gggcccgccg cgccgtatgc ggcaggctga gccggtcgag gtggccgacg
    27541 gcgtcgcgga cccgggcggt gatcatgtcc tccacctgct ggggggcctt gagcgtgagc
    27601 atcagctcgc gtacctcccg caggtcctcc tcggtgacgt cccggcggcc cagtacgccg
    27661 gccagacgct cgcgctgtgc gggcagggcc gcccgccagg ccgcggccag cagcgcggtc
    27721 ggccgctgcc cgcggatgtc gtccaggctc gcctttccgg tgcgggcggg ttcgccgaac
    27781 aggcccagca ggtcgtcccg gagctggaac gcctccccca gcggcagccc gtacgccgac
    27841 agggcggcgc gcagcccggg tggtgcgccg gcgagcaggc cgccgatgag caggggctgt
    27901 tcgacggtgt acttggcggt tttgtagcgc accaccttca aggacacctc ggggtccggg
    27961 cgggcgccgg tggccaggat ctccaggcac tcgcccgcga tcagttcccg ggcgaggtcc
    28021 gcccacaccg gtctggcccg ggtcaggtag gccgcgggca ggccgctggt cgcgaacaac
    28081 tgcccggcca gcgccatgag atggtcgccg accagcatgg ccagagcacg ggcggcggca
    28141 cgcgggcgcg gacggtccct gacagccgtg tgcagcgcga cgtgcgcggt gggcaggtgg
    28201 tggcgcagcg ggctgtcgtc gatgaggtcg tcgtggacga ccgcggcggc gtggacgagt
    28261 tcgagcgagg cggccgcgcg gagcagggcg tcgctgtccg gctggccggc cgcacgccac
    28321 ccccagtagc agaacgccgc gcgcagccgc ttgccgtggc cggccgccac ccgtaactgc
    28381 ccggccaccg gagccagcgc gccgtcgatc gcgaggaacc gctcggcttc cgcggcgagg
    28441 aagccggcca ggagcgtgtc gacgcggtcc ttgaaaccgg ccgggtccca gcggtcagac
    28501 atcgccgctg gaggccgcct gccgggcccg ggcgtgctgg gccagtacct ccaggtgggc
    28561 gggcccggcg gcacggcggt ccaggacgag gcggccgcgg gccatcaggt cctggtgcgc
    28621 gtcgcgggcg aggtcgggcc cgtcggagcg acgcagcagc ccccgcagtg tgcccatggc
    28681 cgagccgatg gtggtcacgg ccaggtccgc caggcccgcg acgagcagga ccgcctgctc
    28741 gtcgaggcct cggtcgccgt ctcggccgtc gcctcggtcg tcgactcggc cgtcgcgcgg
    28801 agcgtgcgtc attccggtcg gtcccccctg ttgtcggtgg tcggtcccgg gcggcggatg
    28861 ccggatcccc gaggtgccga tcacagcatg accagaggtg ttgctccgct cgccccgatt
    28921 accgcatcga gtgacctgcg ggaacgcatg tccggacgga ggtcggcagg gactgagcac
    28981 ggcgttcgga cggcgtggcg ttcagacggc ggcctggggc tgttccgggc tgaggtagtg
    29041 gacggcggtc cgctccgcgt gcggggccag gagtccctgg agttcgtcgg cggcgagctt
    29101 gaggaggtcg ccgtcgcggc cggcgtgcag ggtctccagg aggaacgcga cgcgggtgga
    29161 gtcggcggtg acgcgggtgc ggtgggcgtc gcggtggttc cagtggcggg tcaggacgcc
    29221 ggtggcgtcg gcgtagacga tctcgccggg cttggggtgc tcgacggtgt cgggttcgcc
    29281 gagcggggtg aacgtctcgg tgccggcggc gtggcggatg tcgacgtctc cggcgacgtg
    29341 gtcgaggtcg aaggccccgg cgggcagtcc gtggcggacg gagacggcgt tgtacgagtc
    29401 gacggccggg ttgatacggg gcagcgtgcc cctcttcgcg aggcgccggc cgagcgcgtc
    29461 gacgctgggg cggatgcggc gggggttggt gccgaaggag cggtaggcgg tgtgccaggc
    29521 ctcgatacgg gggtcggcct cgtcggcggg ctgccaggtg ccgtcggcga gctgccgctc
    29581 cagctcctcc agcgcgctgt cagtgtccgg ccagggttcg tggccacgca ggccggtggc
    29641 ggtgacgagg gcgatgaggg tgtcggggaa ggcgtcggct acggcggggg cgatgcggaa
    29701 ggcggtcatg ggtgcggggt ccgttcgtgc ggggtgggtg ggcccgttcg tgggggtggg
    29761 caggtcaggg ctgccagggg ccgatgcggt cgaggcggcg gagctgctgg cgggcggtgg
    29821 cggtgtcgag gccctggtcg cgggtggtga ggtggccggc cacggcggtg cggtgctcga
    29881 cgggcttgtg gtcgtcgtac ttgaacttgg cgcgtacgtc ggtcacttcg aggcgcaggc
    29941 cgcggatgcc ggacagcatg cgcccgtacg gcggccggtc ggcggcgacg ggggcgtggt
    30001 cgccgtcggg ctggaagtgg gcgagctggc ggcgcagcag ctcggccttg gcctcggggt
    30061 cgtcgacggc gtgggcgcgg caggtgaact ggacggccgc gtagtagctg gtgggcacgc
    30121 cgtcggtggg cgggatgccg ggcttggccc gccaggggcc ggggatgaag gcgtagtcgc
    30181 cgatgacggt gaaggtgacg ttcgggtcgg cctcgacgaa cgcccagacc gggttggggc
    30241 gggccaggtg gatcaggagg tcgccgccgt cgccggtgaa gtgggtgggg accgtcgccg
    30301 gggcgtgtcc gggcgggccg ttgacgctga ggatgccgaa gtcgtggcct tcggcgatcc
    30361 aggcctgcca ttccgcgtcg tcgagactgg cgtcccaggg ctggatgaac acgggcttct
    30421 ccttgcggcg gcggggcggg gctcggtggt gggtgagtag gagcggtctg cgcaggcgag
    30481 tgtggagcga cggctcaggt gagggcgagg aggctgaccg cgacggcggc cgtgccgagg
    30541 ccgacgagct ggccgcggtg gatgcgttcg gcgaggacac cgcgagccag caggacggtg
    30601 cctgccgggt agagggcggt gatgacggcg acgacggtga ggtcgccgct gcgggcggcg
    30661 agcaggaaga gcaggttcgc cagggagtcc aggactcccg cggtggccga cagcgcgtag
    30721 gcggggcgct cggggccgag cctgcggcgc aggaggccgg cggcggccag ggtgacggcg
    30781 gaggagacgg cccggccgac gatcagcggg gcgacgccgc tgccggacgg cgcctggtgc
    30841 aggcagacga gctgcagggc gatggcggcg cccgcgccga aggccaacag cagcgccgtg
    30901 cgggaggggc gggccgagcc cgcgccgtgt ccggcgctga ccaggacgac ggccagcagg
    30961 gcgaggggca gcccgatgac gccggcggcg gtcaggtgtt cgccctggac taggccgacg
    31021 gcgaccggca gcgcggcgga gacgagtgcg gtcaccggcg agaggacgtt caccgggccg
    31081 atcgcgaggg tgcggtacag cagggcgaag gcggcggccg aggcgacccc ggacgcggcg
    31141 ccccagccga gggccgccgt actgaacgac gcgccgagca ccggccacag cagcagctcg
    31201 accgcgaggc tggccggggc ggccaccagc acggtccgca gcacatgggc cttgcgggcg
    31261 ccgaggccgc cgaggaagtc ggcgcacgta ggcgagtgag ctgcccaggg ccagcagcag
    31321 agcgatcacg gcacatccct taccattcca gcagaacggc tccacggtac aacgaaccga
    31381 ccgcccggtg tcaacgtaac gaccacccgg tgcatcggaa cgacctaccc ccaaggacgg
    31441 tgatgaggtg gccgagacag ccacggcact gcggacggtc gcccacaacg tccgggcggc
    31501 ccggatccgc gcgggcctgt cactggagga actcggccgg cgcgcccagg tcagcaaggg
    31561 cgccctggtc gcactggaga aggcgcaggg caaccccaac ctggccaccc tggtccggct
    31621 ggccgacacc ctgggcatct cggtgtccgc gctgatgcag ggaccgcacg aggggcgggt
    31681 gcggatcgcg gcagccgatg ccgtggcccc gctgtggacc ggcgagcggg gcagcgaggc
    31741 gcggctcatg ctgacgacct ccggcccggc gccggtcgag gtgtggcgct ggcgcctgga
    31801 gccggacgag gagtatccga gccatcccca tcaggcgggc gtcgtggaga cggtcagcgt
    31861 cacggccggc cggatggtcc tggtcgtcga cggtacggaa cacacgctgg aagcgggcca
    31921 gacggccacg ttcgacggcg acacgtccca cacctaccgc ggcgcgggca ccgggccctg
    31981 ccacctgatc atgacggtcc acctgccccc ggggcccgcg gccgggggct gagcggcccg
    32041 aggctgggcc ggccggcccc aggccgacgg cgcgcctacg gcgccggccg cactggagag
    32101 ctgagcggac caggccaccc gccgactctg ccgggaagcg gcaccggcgc cgggccggtg
    32161 ctcagggttc caccccgcag cgtcgcgcga tcgcttccag gcgttccagt tcccggcgtg
    32221 ccgctgtcag gtgggcgagg tcgagggcca tgcccgcgcg ggcgcagacg tagaggatgt
    32281 cctcacgggt ggcggcgtcg aggccggggg cggtccggag gcggcggccc gtgacgcgca
    32341 ggtagagggc gacgctgtcc aggtcctccc gaagctggag cggaaggacc tgccgtagct
    32401 cgtccttggc gtagtcacgt gcctggcagt ccgccgcgca ggggtcgggc tccacggggg
    32461 cgaaggcaag gccggcgtca cgggcctcgt cgtacatctc tcccaacagg gtgcgcgcgt
    32521 aggcgggatc gccctcggcg gctgccgtgc gggccgactc cagcagggcc cccagttggg
    32581 cgcggacctc gggatcctcg cccgtacggg cgttcagata gccggaccac acgtcgaacg
    32641 ccttgctcaa ctcggcatcc agcatgatct cgtacacgtc cggcaactcc gccgcccttt
    32701 ccgccgccct gccccgtccc accccgtcct gacctgtcct gacgtggacg ggagcggaca
    32761 ggatagggcg gacgcccgtc tggtttcccg cgaattacgt ccccggacga cggcggacaa
    32821 caccggccgg cccctagggg cgggcggggc gcggacgggg tcacagctcc agggcgagtc
    32881 cccataccag cgcggccacg ccgaggaagg gcgccagcag catcacgagg aaggccaggg
    32941 tggagagttg gcccggatcc tgttgtccgg cctcccgcca ctgcccgtta ctccacgcca
    33001 cggccacgaa cagggcgatc gccgcccagt aggggccgtc gtgccggaag agcaggaccg
    33061 cccccaccgc cagacacagg aacgagaacc ccgcgatgta ggcaggcttg atgccgtaga
    33121 gcgtcaactt ctctcccccg atttccagtt ggtcgacaag tcagtcgatg agtcagtcaa
    33181 tgagtgggtc catgagtcgg tcatggagac gacggccgcg ctgacgcggc gcagtcggtc
    33241 aggggccgcc gtagccgccc gtctcgtcct cggggtcctc ggtcgcgtac agggaaggcc
    33301 ccaggcgccg cgccagttcg ttcccgaaga cttgtgtccg ggtcacgctg ccgtcggctt
    33361 ccctcgccag ttccgcgtag aacgccatgt cgatccagtc gccgggatgg tggtggaaga
    33421 gctcgaccgt ggcctgcgga tactccgcgc gcagccgggc gaacgcctcc tcgaccccct
    33481 ccgccctcat cgcgcccgga ccgctgatca ccgccgtcag ccggccggcc tcccactgcc
    33541 acacccggag gtgcacactg cccatcacgt cgagaccctg ccatgggtct tcgtcccgga
    33601 tcagctccgg gtactcggct tcaccggcca tccgcccccc cctgtgctct gccgttgccg
    33661 acagtgtcac ctccggtggt gcgccgtgta cacggtcgcg gtcatgggcg ccgtcacccg
    33721 tccggcgccg aggcgttccg tcatcctccg cgccaccgcg gcccggaggg cctgggcatc
    33781 ggcacggtcc tgcacagcgg cgctcaccgg tgtgccggtg aggaacccga cggcgacgga
    33841 ctcggccgac tccgcctcac cctgcaacgt cacctcctcg acctcggcca acaccagtcc
    33901 cgcgtccgcg agttcggcgg cgaccacgga cggatccgtg tagccgtgcg gcacttccct
    33961 caggaactgg ggcgcgccct cgggcatgca ttcgtccagg gcgctctgga cggcggcatc
    34021 gaagccatgc gagtccagcg ggccccagct gctgaacagg aaccgtccgt gcggcgccag
    34081 gactctgcgc acctcggcga aggccgccct cttgtcgggg aagaacatca ccccgaactg
    34141 gcacacgacc aggtcgaagc cgccgtccgg gaagggcagc tcctgggcgt ccgcctgccg
    34201 ccatcgcgca cgcggctccc gcgcggaccc cgtcgccacc atcgcgtcgt tgaggtcggt
    34261 cgccaccacc gaggcctcgg gcactgccgc gagcagggcc gaggtcagca ctcccgtccc
    34321 cgcggcgagc tccagcacac tgcgaggccg cagcgccgcc gcccttgcgg ccaggtccgc
    34381 ggcgaacggg cggaagagga ccggcacgag gtggcgttcg tacgcctcgg gcatggaccg
    34441 ggtccaccgc cggttcacat cgtctgcgct cacctcaccg acactagctc cgcggaggcg
    34501 tcctacgacg gaacgccttg gccgacgcga cgggcgcctc acgcacctcc cccgaagaac
    34561 gtcgcgaggt cgtgctccaa catgcacaac agcgtcccga agtctgaggc ccgcccggcg
    34621 gccgacgccg agtgcgcggt caccacagga ggtctgtttc tgacgggccc tggggaccgg
    34681 cgagcgggat gccgccagct catggtggcg gcacaacgac acccgcccct ctacgccgct
    34741 ctcgtcgccg agtggcaggc cgccggccgg atggtccccg gcgctccgga cgaccaatgg
    34801 gccgccctcc ccgtccctca ccggaacgga caccgccctc ccgtcgttcc cgcggcagca
    34861 cctccgggcc aatgggaacg gatcgtcgac ctcccgaccg tacggcaggc caggcgggcg
    34921 tcagcaccga ccgagcgccg tcccgccgcc cgctccccgc gcagccacgt cccggtcggc
    34981 ccgtcggcga ccgcgagccg cccgcccccg tccgaggggc gttgatcatc gtcgtacgaa
    35041 cccggaggtg ttccgtccgg cacggggtat cggcactacg taggccgatg acctgctgaa
    35101 ggagcgaaga tgaccgacga tgcctacctg ttcctggtcg acggggccgc cgaggggccg
    35161 ggtgtgccgc ccgccgagct cggtgagccg gcctgcatgg acacctccgc cgtcagcgcc
    35221 tggctcgccg cccacgacgt gaccgcggtc tcgccccggc tgcgtatcgt gccgccggag
    35281 gagacggacc tgatcccctc cggtgccgag cggctgcccg tgcccctgag cgaggaggag
    35341 ctgacccggc tgcgccgccg gcaggccccc gcggcgacga ccgcgatcga ggacgagctg
    35401 ctggcgtacc gggactgcgc cgacggccgg gacgagcttc tcgcccgtgc cctggccgcc
    35461 ggggtgcccg cccaccgggt cgcggaactg acgggcgagg acctgcgcgt cgtacaggcg
    35521 gtcgcccaac ggtgaccgcg gcgaaacgaa cgcaccacac aatcccccaa gtcccttcat
    35581 agatgccgca cttcggggta cccgggcgat gagccggccc tcaccgacca ggtctcccct
    35641 ccgggagatc ccaccgaagg agtgcagatg accacgcagt acaccaacca gcccaccggc
    35701 cagcagagcg cctcgaccgg caacgtgctg agcatcatcg ccatcgtgct cggcgtggtc
    35761 tccttgctct tcctgccgat cgtgttcggt ctgatcggcc tggtgctggc catcgtcgcc
    35821 aagacggtcc ggcacgagcg gctctccacc atcgccatcg tggtcagcgc cgtcggcctg
    35881 ataggcggca tgatcctggg cgcactcgtc gtcaacacgt gagtggccac cgtgtgaagg
    35941 gcgttcgggt acgggtacct gtgcgccgcg cagccctggc cgccttccac gagaggcgac
    36001 cagggccgcg tcgtgcacag ggacccgcgc ggcgcggcgc agccgggtga gcgtctggcc
    36061 tgccgggcgg cgttacgact gccgcgggcc ggccgcccgg cggaggcggt tggcgatggc
    36121 gaggcccagg ccctcctccg gcggcaggga cgcgatgatg aggtcgcagc cccgctggtc
    36181 gagttcgcgc aggaagccgt acagctcgcg ggcgtacccg gccatcgagg cggggaccgg
    36241 caccacggcg tgcgccttga ccggcgtgcc gacgagggtg gacgggagca ggacgccgac
    36301 ctggtggccc tgctcctgcg cgagctgtgc ctccgcggcg atctgctccg gctcgacgag
    36361 gacgacccgg gcggacggcg cgtagtgcga cgggtgctgg cccggtaccc ggacgtggct
    36421 cgtggcgggg acgtcgaggg ggcggtccag caccgcttcg aggtcctccc gggtgacgcc
    36481 gccggggcgg aggatggccg gggtctcgcc cgtgacgtcg acgatggtcg actcgacgcc
    36541 gacgccgcag gggccgccgt cgaggacgaa gtcgacggcc tcgcccagct cggcccggac
    36601 atggtccgcg gtggtggggc tgaccgagcc aaagcggttg gcggacgggg cggtgactcc
    36661 accgccgaaa gcctccagca acgcgagggc ggcggggtgg tcgggcacgc gcacggcgac
    36721 cgtctccagc ccgccggtgg cttcgagggg caccctcggg ccgcgccgca ggacgagcgt
    36781 gaggggcccg ggccagaagt gctcggccag caggcgcgcc gtcgcgggga cctccgcgac
    36841 ccagtcggcc agctggtccg cgccgccgat gtggacgatc agcgggtggg tgggcgggcg
    36901 tcccttgacc tggaagatgc gcgagacggc ggcgggattc tcggcgtccg cgccgagccc
    36961 gtagaccgtt tcggtcggga gggccaccag gcccccggcg cgcagcacct cggccgcctt
    37021 ctcgatgtca ctggttcttg ccatcactcg cgcaatcttc tcatcttccc gcacgttccc
    37081 tgaacggcgt gtccgggtgc cggacccgga ggcgtatcgg ggcgtctcat gcgggtaccg
    37141 gggcggctcc ccacgcctgc gcgcacaggg cggactcgac cgtgtccgtg tagaccgcgg
    37201 cggcgagcca ggcgcgggcg aagcggtccg tgtcggccgg gagcagccgg ccgaaggcgt
    37261 cgcgggtccg gtccgcggcg gcggcgtgca ggtcgccgag gaggtcggcg gccgtggcga
    37321 gaccggcggc ccggagtcgt acgccgtcgc cctggccgcc ctgggtgaac gacagcacgc
    37381 ggcggccccc ggacaccgcc tggtgcaccc ggcggcgcag caggtgcagc ggggcctcgt
    37441 cccccgcacc ggcgacggcc gggacggcgg gcgcgggcac cggctccgtg ggcaggtccg
    37501 cgcgctggag ccggtccagg cccaggtcca cccgcgccgc cgggtcggcg gggtgctccg
    37561 ccgcgagcag cagagcgcgc gggcggggtg cgggcaccag gcgggccacg acgcgcaggc
    37621 ggctgcccgg agcgctcgcg agcagacgca ggttgtcgcg gcagggcagc gccgggtcgt
    37681 cgtgggcgac cgccaggcgt acgggtacgc ccccgcagtc ggccagcaag cagtcgcccg
    37741 ccgcctcccg gaccgtgccc accagcgtca cctccaggaa cagcaggtcg tgctccccgt
    37801 tcagggcgcg ccgcacctgc tcggctgccg gtacggccca cagccggtcc agcggctcct
    37861 cgcgccaggt ggcgccggac gcccgcaccg cccgtacccc cgcgcccgcg ccgaggcggc
    37921 ccgtcggcga gacggtcgca ccggagacgg ccagccctgc ccgggccagt tcccggtggg
    37981 tcagggccgt gtcacccatg cgcacggtcc ggtcggcggc gccgacggcc cgggccggcc
    38041 cgcccggcgc cacgtccgac accgtgtaca ggcggccgtc ggcgtcggcg gtccaggtca
    38101 ccgcgcccgc gtagccggtg gccgtgagga cgggctcgct gaagaggccg tacaggcgca
    38161 gggagccgtc ggggcggtac ggctggcggg cggtgccgcg caggtcggcc agttcgggac
    38221 cggtcgcgtg cggcagccgg tgcgtgacgc cgaggactcc ggccagtgcc gcggcgaggt
    38281 cggcgaggcg gtacccaggg tcggcggaac gggctgcccg taccccggtc accaccgaga
    38341 cggccgccgc ggaggcgcgc gggagaccgg cgaggcgcgc ggagtgcgcg gcgcgcagca
    38401 gctccgcctg gaggacggcg ccggccccgt ccgctccggc ttccaggacg gcggcggcag
    38461 cgtcgtacac cgccctggcc gcggcgaccc ggccggcggt gg
//
