LOCUS       NZ_BNBR01000001        47350 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces griseosporeus strain JCM 4766 sequence01, whole genome
            shotgun sequence.
ACCESSION   NZ_BNBR01000001
VERSION     NZ_BNBR01000001.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces griseosporeus
  ORGANISM  Streptomyces griseosporeus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 2104813)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 112X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014656055.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 05:04:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,365
            CDSs (total)                      :: 7,282
            Genes (coding)                    :: 7,186
            CDSs (with protein)               :: 7,186
            Genes (RNA)                       :: 83
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 96
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 96
            Pseudo Genes (frameshifted)       :: 41 of 96
            Pseudo Genes (incomplete)         :: 61 of 96
            Pseudo Genes (internal stop)      :: 11 of 96
            Pseudo Genes (multiple problems)  :: 15 of 96
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:46:46
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 284341
            Orig. end                         :: 331691
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BNBR01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..47350
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..47350
                     /SMILES="NC(CO)C(=O)N1C(CCC1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..47350
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:27350](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..27350
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     misc_feature    complement(539..548)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.63"
                     /tool="antismash"
     gene            586..1329
                     /locus_tag="IE308_RS01190"
                     /old_locus_tag="GCM10018783_02630"
     CDS             586..1329
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (24-139). E-value: 1.5e-19. Score:
                     61.3. Matches aSDomain: nrpspksdomains_IE308_RS01190_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569873.1"
                     /locus_tag="IE308_RS01190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02630"
                     /product="cyclopropane-fatty-acyl-phospholipid synthase
                     family protein"
                     /protein_id="WP_190216193.1"
                     /transl_table=11
                     /translation="MNREQMSRLAHADHPIAAPLDDDAVQRLLDRAVPRADARVLDLGC
                     GGGEWLLRALGAHPRLRAEGVDLSARALAHARERANTLGVEERLLLHQTDAAEFSAPHL
                     FDLVICVGATHAFRGLLATLDAARKHLAPGGRVLVGDGFWEREPGPEAVEMLGDLADLP
                     TTVEQVVNDGWTPVHGHISTRHELDAYEWAWTGSLSAWALDHLGDPGSAEALEAAAAHR
                     DGWLRGYRDAFGFVTLVLRQTPTNG"
     misc_feature    594..607
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.51"
                     /tool="antismash"
     aSDomain        658..1002
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS01190_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.50E-19"
                     /label="IE308_RS01190_oMT.1"
                     /locus_tag="IE308_RS01190"
                     /protein_end="139"
                     /protein_start="24"
                     /score="61.3"
                     /tool="antismash"
                     /translation="VQRLLDRAVPRADARVLDLGCGGGEWLLRALGAHPRLRAEGVDLS
                     ARALAHARERANTLGVEERLLLHQTDAAEFSAPHLFDLVICVGATHAFRGLLATLDAAR
                     KHLAPGGRVLV"
     misc_feature    1387..1402
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 21.84"
                     /tool="antismash"
     gene            1520..1936
                     /locus_tag="IE308_RS01195"
                     /old_locus_tag="GCM10018783_02640"
     CDS             1520..1936
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980768.1"
                     /locus_tag="IE308_RS01195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02640"
                     /product="ATP-binding protein"
                     /protein_id="WP_110635512.1"
                     /transl_table=11
                     /translation="MDGRSLRAVGWARSLPLDSQIKTARDWARAHLDEVGWTSHHPDTA
                     DDVLLVVSELVTNAHVHGHSSAQLVMSWDSQCLHIAVHDASPVLPTPREPEELRPGGRG
                     ILLMEALADRWEARRCPHGKTVIACFQPPADPER"
     gene            complement(2028..2408)
                     /locus_tag="IE308_RS01200"
                     /old_locus_tag="GCM10018783_02650"
     CDS             complement(2028..2408)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE308_RS01200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10018783_02650"
                     /product="hypothetical protein"
                     /protein_id="WP_190216194.1"
                     /transl_table=11
                     /translation="MHRTSSHRLTKIMITAAVGVMAAAGMAAPASAAQAPHAGRTNVAA
                     EYETVTTWVQGNVRIGPSTGWRIAYTVAANQNLIGVCWREGGMVTANGYSHDKWVYLSD
                     GNYIWGGLLKGNEVGNVSSHCW"
     gene            complement(2613..3521)
                     /locus_tag="IE308_RS01205"
                     /old_locus_tag="GCM10018783_02660"
     CDS             complement(2613..3521)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016430513.1"
                     /locus_tag="IE308_RS01205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02660"
                     /product="EamA family transporter"
                     /protein_id="WP_190216195.1"
                     /transl_table=11
                     /translation="MEGNLRWVAVTAIAPVAWGTNYYVTHEFLPADRPLYGAAARALPA
                     GLVLLALSRRRPHGSWWGRSAVLGLLNVSIFFVLVFAASQLLPTSVASTVMAVSPLTMM
                     FIAWPLLSERPTPAHIAGAVVGLGGVCLTLLTGVQGTSVPGVLASLAAVLVSSLGHLLA
                     KRWSTGADLLASTAWQLTAGGLFLLPVAAAVEGPPPKLPMPVLLAFAYVALVATALAFT
                     AWFTGLRHLPASTVGLIGLLNPVTGVLLGTAVAGELLTLQQTCGLVLVLTGVVLGRPKR
                     PRRGRRALDQVVDECPARAPS"
     misc_feature    3525..3541
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.96"
                     /tool="antismash"
     gene            3541..4107
                     /locus_tag="IE308_RS01210"
                     /old_locus_tag="GCM10018783_02670"
     CDS             3541..4107
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015610451.1"
                     /locus_tag="IE308_RS01210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02670"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_229908645.1"
                     /transl_table=11
                     /translation="MEENVVGGAGRGAQDHVARIQADWRRERPALDVRPQGVIGRLHRL
                     ADRLSDELRLVYGRYGLSEGEFDVLCALRRAGEPFERAPGELAAHTMVTTGAMTKRIDR
                     LERAGLVTRRRSADDQRGRIVALTGPGRELIDQAFTEHMHNERRLVDMLTPAEAESLET
                     VLTGWLSRIEHRADGPVTRSGPPET"
     misc_feature    4171..4186
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     gene            4236..4979
                     /locus_tag="IE308_RS01215"
                     /old_locus_tag="GCM10018783_02680"
     CDS             4236..4979
                     /NRPS_PKS="Domain: PKS_KR (7-149). E-value: 1.4e-10. Score:
                     33.3. Matches aSDomain:
                     nrpspksdomains_IE308_RS01215_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016570766.1"
                     /locus_tag="IE308_RS01215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02680"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_190217311.1"
                     /transl_table=11
                     /translation="MTNMTKTSVLVTGGNKGLGLETARRLGELGWTVFLGSRDEGRGRA
                     AADKLAAEGVDVVMVPLDVTSDVSVAAAVRLVRAHTDRLDVLVNNAGTPGHIVPPADAT
                     VEEIHPVFDTNVYGPIRVTHAFLPLLQAADHPRVVMVSSGGGSFSVVTDPEQPVSKMHE
                     LAYSTSKAALNMITVRYAQALPGIKFNVATPGEVANRKFAATDMNNHTGALTVTEGTDS
                     IIRLATLGPDGPTGTFVDRLGPVGW"
     CDS_motif       4257..4397
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS01215_0001"
                     /evalue="7.20E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE308_RS01215"
                     /protein_end="54"
                     /protein_start="7"
                     /score="18.7"
                     /tool="antismash"
                     /translation="SVLVTGGNKGLGLETARRLGELGWTVFLGSRDEGRGRAAADKLAA
                     EG"
     aSDomain        4257..4682
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS01215_PKS_KR.1"
                     /evalue="1.40E-10"
                     /label="IE308_RS01215_PKS_KR.1"
                     /locus_tag="IE308_RS01215"
                     /protein_end="149"
                     /protein_start="7"
                     /score="33.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="SVLVTGGNKGLGLETARRLGELGWTVFLGSRDEGRGRAAADKLAA
                     EGVDVVMVPLDVTSDVSVAAAVRLVRAHTDRLDVLVNNAGTPGHIVPPADATVEEIHPV
                     FDTNVYGPIRVTHAFLPLLQAADHPRVVMVSSGGGSFS"
     gene            5163..6605
                     /locus_tag="IE308_RS01220"
                     /old_locus_tag="GCM10018783_02690"
     CDS             5163..6605
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016432724.1"
                     /locus_tag="IE308_RS01220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02690"
                     /product="cytosine permease"
                     /protein_id="WP_190216197.1"
                     /transl_table=11
                     /translation="MNTAPRPLLPDAQKTEPAPIPSSFDAHGVEPIPENGRDSSPRDQW
                     WIWVGANVAPINWVLGALGITLGLNLVETLIVISLGNIVGCGVFGLFNMMGHRTGVNQM
                     VLGRAAFGRKGAVVPGVMQGLLTMGWVGVNTWVVLDLAVALLGKIGIHGGEGLKYAVAG
                     VVMAAQLGLAVFGFYAIRTFERWTVPATVLVMAVMTVLSLTQSDLHWTAGTAEGGTEKV
                     TAVTQLLTAIGIGWGISWVPYSADYSRFVPARFSGRSVFWATALGMYVPTVWLAALGAC
                     LATTGQGGDPSELVISAFGVMALPVLLLIMHGPVATNILNLYSCALAALSVGVRAARWK
                     VTLVAGAVATVVLLVFMQSHSFAESFDHWMTSILVWISPWAAVMLTEFFVLRRSRLDVA
                     ELFDDRAPAWRWRALLALAAGIAAAWSWQYGLVPLMQGPLARSMHHTDFSWLSGAVVAG
                     GLHYLLTRSENRAARDRSALAD"
     gene            complement(6635..8200)
                     /locus_tag="IE308_RS01225"
                     /old_locus_tag="GCM10018783_02700"
     CDS             complement(6635..8200)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037653.5"
                     /locus_tag="IE308_RS01225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02700"
                     /product="PucR family transcriptional regulator"
                     /protein_id="WP_190216198.1"
                     /transl_table=11
                     /translation="MLTLRTLCERRDLELTVLVPGPEGALDCEVSWTHNTELPDPSPYL
                     RRGELVMTNGLWHIAGHSAESFVHRVQDAGASGIVFGLRREMPATPADVIDACRKAGMP
                     LLELSVDVPFTALSQAAARTLAEQRQSALMASVRRGNALADAISSGTGAGGVLRVLRRD
                     HDLRLAVVDRMGHLLGSAGAGLTDDDLVVVARAVARRPPPLEVTLSNDSAALFPVGVFG
                     EADAALVCLRSAAALDEAERGALEQAAHFLGMETARLHAVQATEMRFAGELIDMIFAGA
                     GASREFAARLKTFGIEAGDPLAVCALALAEGEAAVSPVPANAVMAFFVSEGVPAVVAPG
                     GRDTVALFPWRLTEGELEASMTRLLGLLDRQLPAQKVVLGYGGPAGDSTKLKVPLMEAR
                     EACQLLARGSSAARMARFAELPSHSALLGRLDGQVVQRFADALLTPLRDHDAQRGAQLE
                     LTLRTFLANEGQFAATADALYIHVNTLRKRLTRIGELTGRDPMKFEGRVDLFLALEADA
                     LVRS"
     misc_feature    complement(8321..8337)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.41"
                     /tool="antismash"
     misc_feature    complement(8399..8419)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.81"
                     /tool="antismash"
     gene            8410..9033
                     /locus_tag="IE308_RS01230"
                     /old_locus_tag="GCM10018783_02710"
     CDS             8410..9033
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016432718.1"
                     /locus_tag="IE308_RS01230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02710"
                     /product="DUF1989 domain-containing protein"
                     /protein_id="WP_190216199.1"
                     /transl_table=11
                     /translation="MTQATQVCASIDIPAGEGRAVHVDAGQRVKIIDVEGRQVGDVFAF
                     ARGDIREYHSASHTRAHVNRLFPAVGEQFVTSLRRPILTLVEDSSPGRHDMLIAACDAA
                     RYAALAAPSDHASCAQNMHDALAAIGLSADLVPQPINVFMDIPVSNDGALTWETATSRP
                     GDSITFQAEMDCVLVVSACPQDLVDINAGAPSPLRLQIENGATA"
     gene            9030..10157
                     /locus_tag="IE308_RS01235"
                     /old_locus_tag="GCM10018783_02720"
     CDS             9030..10157
                     /GO_function="GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_process="GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016432719.1"
                     /locus_tag="IE308_RS01235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02720"
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="WP_190216200.1"
                     /transl_table=11
                     /translation="MNALAPHPALEPVTLAGAKLANRLAVAPMTRVSAREDGTPTEAMA
                     RYYSAFASGGFGLVITEGTYTDDRHSQGYFFQPGIVTESHVRAWRAVAESIQAGGARAV
                     MQLMHAGALSQGNRFRTDTVGPSAVPPKGRMMPEYGGSGRWPTPRAMTDDDIETAVQGF
                     VSAAVNAREAGFDGVEVHAANGYLLDQFLTDYTNLRTDSYGGPVANRIRLTAHVTERIR
                     ARIPDEDFWIGVRLSQTKVNDFHHRWAGAADARVVFTSLAKAGASYLHIASEGRDWIET
                     ARLDSGDTITALAKKVTGLPVIANGGMHDLDQAARLLEGGHADLLSLGRGALANPDLPN
                     RVAGGHDLDAFDHAMLQPRASLDNAEQWRRRNMSA"
     gene            10222..11073
                     /locus_tag="IE308_RS01240"
                     /old_locus_tag="GCM10018783_02730"
     CDS             10222..11073
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016432720.1"
                     /locus_tag="IE308_RS01240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02730"
                     /product="polysaccharide deacetylase"
                     /protein_id="WP_190216201.1"
                     /transl_table=11
                     /translation="MDHSWRGRAAAVATLTFDVDAEAPILAHGAHYATHASTMSHQSYG
                     PDVGVPRILDLLDETGVPATFFVPGWVAEQRPGLAASIVERGHEVAHHSYSHRPPTEMT
                     ADEERADFERAMEVFAAQDIPIAGHRAANWSSTWLTSSLVAEYGLLYDSSLMGDDRPYA
                     LRTEAGTIVELPVHWSLDDWEQYAFLPAPHIGSVIESPRKVLEMWTDELDAMRHYGCLF
                     NLTNHPFLTGRPSRAVALRKLIEHARERGDVHFARCSDVARAARADTSLPLRSPVPPKP
                     AD"
     gene            11100..12413
                     /locus_tag="IE308_RS01245"
                     /old_locus_tag="GCM10018783_02740"
     CDS             11100..12413
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016432722.1"
                     /locus_tag="IE308_RS01245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02740"
                     /product="amidase"
                     /protein_id="WP_190216202.1"
                     /transl_table=11
                     /translation="MSEIEALAAALRAGETTAEALARRSLARIADRNGELGAFAFVDHE
                     GAASAARRADDELRNGIDRGPLHGIPVAVKDLIDVKGLPATRGSAHFAGHRAADDATCV
                     RRLRSAGAVIIGTTVTHEFGYGPTGDRGRHGPARNPRDPRRMAGGSSGGSAAAVASHMV
                     PVALGTDTGGSARIPAALCGIAGYKPAFGRLPSEGVFPLAPSLDHVGVLGVTARDCRLV
                     VEALAPERPVPRGALAAVARIGWLEAAAHAPVTPAVADVTRRALSHHDVAQVACDALDA
                     VWETFSAIQNSEAFATHADRVREHPELFDAEVLDRLREASKTPGWRYVRALHARETARR
                     SVNGVFDRFDLLASPTVGITAPQLGRREVTVSGSSRSVRSALLALTSPWNVLGFPALSV
                     PAGCVDGLPVGLQLVCPPDREDLLFAVADGVAASVAET"
     gene            complement(12444..13232)
                     /locus_tag="IE308_RS01250"
                     /old_locus_tag="GCM10018783_02750"
     CDS             complement(12444..13232)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003983475.1"
                     /locus_tag="IE308_RS01250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02750"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_190216203.1"
                     /transl_table=11
                     /translation="MSQLNGDSFPVRTFGGPTALFEYGGLRFLTDPTFDGPGDYPSAGP
                     TLTKTAPSTATPADLGRVDVVLLSHDEHADNLDTSGRALLADIPLTLTTPGGAQRLGKE
                     AKGLADWETVELERPGGGTLTVMGVPAVHGPGPREAVEPYTGQVVGFVLTGEGLPTVYV
                     SGDNASLDAVKEIAERFAPVDTAVLFAGAPRFPMLFDNNPLVLDSAQAAEATRILDARR
                     VVPVHHDSWAHFTEGRDELEAAFTAAGLADRLDRDWLQRA"
     misc_feature    complement(13244..13257)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.21"
                     /tool="antismash"
     gene            13317..13934
                     /locus_tag="IE308_RS01255"
                     /old_locus_tag="GCM10018783_02760"
     CDS             13317..13934
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003983476.1"
                     /locus_tag="IE308_RS01255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02760"
                     /product="ABATE domain-containing protein"
                     /protein_id="WP_373314404.1"
                     /transl_table=11
                     /translation="MRGMDDVPATDAAQAALPPAPGADRYRSLDFADTAATLPAGQSYD
                     LLAAPESAMRWLAAHELTAPDVRLYEVCARRMRTLRAHVRALFAARVDGTTPPEESLRA
                     VNEALTAVPTAPLLAWDGAQGPRRIHAHPTDRAVNHALATLAADAADLLTGPDAGILAA
                     CGSPPCDRFLLRTHGRRHWCSTRCGDRARAARAYARRSGTPS"
     gene            complement(14013..15536)
                     /locus_tag="IE308_RS01260"
                     /old_locus_tag="GCM10018783_02770"
     CDS             complement(14013..15536)
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007445297.1"
                     /locus_tag="IE308_RS01260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02770"
                     /product="glycosyl hydrolase family 18 protein"
                     /protein_id="WP_190216205.1"
                     /transl_table=11
                     /translation="MRRVRSFHAALAAAATAAAAVGLALTGAGTAQAATPLPHHVFAPY
                     FEAWTGESPAALSAQSGAKHLTMAFLQTATKGSCTPYWNGDTSMPIAASSFGADIKTIQ
                     AAGGDVIPSFGGYTADTTGTEIADSCTDVQQIAAAYEKVITTYDISRLDMDIEVDSLDN
                     TAAIDRRNKAIKLVQDWAAANGRKVEISYTLPTTTHGLADNGEALLRNAVANGTRVDVV
                     NLMTFDYYDNQPHDMAQDTQTAAQGLYDLLAELYPGKSAAQLWNMVGVTEMPGVDDFGK
                     AETFTLANARTVYDWAVAKGINTLSFWALQRDNGGCPGGAAADNCSGIQQNTWDFTHIF
                     APFTDGTSTPSNDFSVALTPASATVTAGQSVTATVKTAVTKGDAQSVRLSVSGTPAGVT
                     ASLSPASVTAGGSSTLTLATTSAAASGTYTVTVTGAGTSGSHSATYSLTVTGGSGNQCT
                     DAPWVKDKVYTGGQRVSHKGHAWKAKWWTTGEEPGTTGEWGVWQDLGAC"
     misc_feature    complement(15629..15643)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.2"
                     /tool="antismash"
     misc_feature    complement(15645..15660)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.38"
                     /tool="antismash"
     misc_feature    15741..15756
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     misc_feature    complement(15864..15879)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 23.8"
                     /tool="antismash"
     gene            15920..16636
                     /locus_tag="IE308_RS01265"
                     /old_locus_tag="GCM10018783_02780"
     CDS             15920..16636
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030844.1"
                     /locus_tag="IE308_RS01265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02780"
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="WP_190216206.1"
                     /transl_table=11
                     /translation="MNMKRRAAVTIGALVAPVLAVSLPASTASAHGWVTLPTSRQQQCA
                     DGVVDCGQIKYEPQSVEGPKGLRSCSGGHAEYAELDDESKSWKVTPVGTTATFTWHNTA
                     RHATANWQYFIGGQKIAEFDGHNQQPAADVSQQVNFGGFTGRQKVLAVWNIADTANAFY
                     SCVDVNIGGGSGGGTGGGDGGGGTCTTPTWDATRVYHGGDTVSYGGHTWRAKWWVTGDK
                     PGTTGEWGVWEDLGAC"
     gene            16692..17243
                     /locus_tag="IE308_RS01270"
                     /old_locus_tag="GCM10018783_02790"
     CDS             16692..17243
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036364.1"
                     /locus_tag="IE308_RS01270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02790"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_190217312.1"
                     /transl_table=11
                     /translation="MFAMSLGDGAELRPLEPWHAEEFLAHMDRGRDFIGAHMELPDLAT
                     DLVSARAYLQRYAEKAASDTGRLYGIWLDGTLVGGVSFPQFDAAAGICEVGCWLEPAAT
                     GRGLVVRAARVVIDWAFRERGIHRVQWFASPKNTPSINVAKRLGMTREGVLRETYLYRG
                     VRHDAEVWSVLAPEWQPLAD"
     gene            complement(17276..17911)
                     /locus_tag="IE308_RS01275"
                     /old_locus_tag="GCM10018783_02800"
     CDS             complement(17276..17911)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1224: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005307488.1"
                     /locus_tag="IE308_RS01275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02800"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_190216207.1"
                     /transl_table=11
                     /translation="MTKQAEGVAGRAARGRGRRPADEVRADVFRVVGEILLGEGIADLT
                     FERVARLSGVSKTTLYKWWPSKGALALDGYFHAVEETLAFEDTGDVRADLLSQLRAFAR
                     VMTATPAGRVVTELIGQSQTDEDLAVAFRSLYSGERRRLAGERLRRAQEQGEIRDDVDV
                     QVLVDQLWGAVYHRLLIPDEPVTDAFVTALVSNLIDGITPPSPTPPSR"
     gene            complement(17996..18895)
                     /locus_tag="IE308_RS01280"
                     /old_locus_tag="GCM10018783_02810"
     CDS             complement(17996..18895)
                     /EC_number="1.1.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (3-169). E-value: 1.2e-13. Score:
                     43.3. Matches aSDomain:
                     nrpspksdomains_IE308_RS01280_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005307494.1"
                     /locus_tag="IE308_RS01280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02810"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_190216208.1"
                     /sec_met_domain="adh_short (E-value: 3.6e-31, bitscore:
                     105.3, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSVVLITGAATGIGNLTARALAAAGHTVYASMRDLHGRNAGRAR
                     ELLDLGRSEGQDIRVVELDVQSDSSAEAAVATVLDEAGRLDTVVHNAGHLYVGYVEAFT
                     PDDIHRLLDINAIGIQRVNRAALPHMRARRSGTLVYVGSTTSVVVPPFLGPYVASKFAA
                     DALAQVTAYEVGQFGIETTIVMPGPFTQGTEHFPNAGHAGDGERTRAYAELDPLVARNE
                     QATEGLFPPGVDAHPRAVAEEIARVLALPHGTRPFRTVVDFSQAGVEEVNEVLRRAQED
                     FVTRLGFGDLLRVKETRS"
     aSDomain        complement(18389..18886)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS01280_PKS_KR.1"
                     /evalue="1.20E-13"
                     /label="IE308_RS01280_PKS_KR.1"
                     /locus_tag="IE308_RS01280"
                     /protein_end="169"
                     /protein_start="3"
                     /score="43.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVLITGAATGIGNLTARALAAAGHTVYASMRDLHGRNAGRARELL
                     DLGRSEGQDIRVVELDVQSDSSAEAAVATVLDEAGRLDTVVHNAGHLYVGYVEAFTPDD
                     IHRLLDINAIGIQRVNRAALPHMRARRSGTLVYVGSTTSVVVPPFLGPYVASKFAADAL
                     AQV"
     CDS_motif       complement(18818..18886)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS01280_0001"
                     /evalue="4.00E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE308_RS01280"
                     /protein_end="26"
                     /protein_start="3"
                     /score="13.1"
                     /tool="antismash"
                     /translation="VVLITGAATGIGNLTARALAAAG"
     gene            complement(19050..19805)
                     /locus_tag="IE308_RS01285"
                     /old_locus_tag="GCM10018783_02820"
     CDS             complement(19050..19805)
                     /NRPS_PKS="Domain: PKS_KR (13-172). E-value: 4.3e-15.
                     Score: 48.0. Matches aSDomain:
                     nrpspksdomains_IE308_RS01285_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487513.1"
                     /locus_tag="IE308_RS01285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02820"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_190216209.1"
                     /sec_met_domain="adh_short (E-value: 8.4e-34, bitscore:
                     113.9, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.4e-07,
                     bitscore: 27.7, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 5.7e-30, bitscore:
                     101.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTSVSTSPRVARVALVTGATGGIGEAVVERLVADGFAVAVHYAG
                     NKGKAEALVEKIAASGGRALAVGGDVADEQQMQAAFDAVETAFGGIDVVVNTAGIMVLA
                     PIAELNLDDLDRMHRTNIRGTFVVSQQAARRVRRGGAIINVSTSVTRTQLPTYGAYVAS
                     KAAVESITLILARELRGRDITVNTVAPGPVATPLFLEGKDEETIGRFAKAAPLERLGEP
                     RDIAESVAFLAGPARWVNGQVLYSNGGLA"
     aSDomain        complement(19290..19766)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS01285_PKS_KR.1"
                     /evalue="4.30E-15"
                     /label="IE308_RS01285_PKS_KR.1"
                     /locus_tag="IE308_RS01285"
                     /protein_end="172"
                     /protein_start="13"
                     /score="48.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VALVTGATGGIGEAVVERLVADGFAVAVHYAGNKGKAEALVEKIA
                     ASGGRALAVGGDVADEQQMQAAFDAVETAFGGIDVVVNTAGIMVLAPIAELNLDDLDRM
                     HRTNIRGTFVVSQQAARRVRRGGAIINVSTSVTRTQLPTYGAYVASKAAVESITL"
     CDS_motif       complement(19704..19760)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS01285_0001"
                     /evalue="3.70E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE308_RS01285"
                     /protein_end="34"
                     /protein_start="15"
                     /score="16.4"
                     /tool="antismash"
                     /translation="LVTGATGGIGEAVVERLVA"
     misc_feature    19820..19831
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     misc_feature    complement(19957..19968)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.72"
                     /tool="antismash"
     gene            20001..27350
                     /locus_tag="IE308_RS01290"
                     /old_locus_tag="GCM10018783_02830"
     CDS             20001..27350
                     /EC_number="6.2.1.-"
                     /NRPS_PKS="Domain: Condensation_Starter (17-320). E-value:
                     1.1e-58. Score: 190.9. Matches aSDomain:
                     nrpspksdomains_IE308_RS01290_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (485-902). E-value:
                     4.3e-110. Score: 360.0. Matches aSDomain:
                     nrpspksdomains_IE308_RS01290_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1006-1069). E-value: 1.4e-20.
                     Score: 65.2. Matches aSDomain:
                     nrpspksdomains_IE308_RS01290_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (1096-1406). E-value:
                     4.9e-51. Score: 165.5. Matches aSDomain:
                     nrpspksdomains_IE308_RS01290_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1561-1964). E-value:
                     3.7e-84. Score: 274.6. Matches aSDomain:
                     nrpspksdomains_IE308_RS01290_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2075-2143). E-value: 1.3e-20.
                     Score: 65.4. Matches aSDomain:
                     nrpspksdomains_IE308_RS01290_PCP.2"
                     /NRPS_PKS="Domain: Thioesterase (2164-2416). E-value:
                     2.4e-39. Score: 128.0. Matches aSDomain:
                     nrpspksdomains_IE308_RS01290_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003982262.1"
                     /locus_tag="IE308_RS01290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02830"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_190216210.1"
                     /sec_met_domain="AMP-binding (E-value: 3.6e-117, bitscore:
                     388.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 3.6e-44, bitscore:
                     147.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.1e-15, bitscore:
                     52.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 2.3e-33, bitscore:
                     113.0, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDTKHVQGERSLLRLDERFPLSAHQRDIWTVCRSGEESAQFTIA
                     GHQRLHGPVDIDVLAGSLDRVTRRHDALLTRFGEADGVPYQWVGHEPLPVEVLDLSGAP
                     DPAAACRRAVDAALTVPLRLRTDRLFHPMLLRQDAETVHIVLRAHHIVADGYALDLFLT
                     RVLAHYESHIRDGSRPGAPDEPSTLGAPSAPGDPCPSYRSFVDEDLAYRGSPEHQADQD
                     FFRERLNGAVPALFARRPAPPGGDRRVSVTLEPEEVAAIRATGTSVFSYVAAALGTYLA
                     RLHGTDSAMLGVAFLNRRGPRHAATVGHFATTLPLLVPVGPADTLESMAGRVAADVRAY
                     RHHERLALGDMPRPAASGDGRRQLFDTTVSYLNLPELPDVAGLVQERTGHQRRHDQDAL
                     AILVVHHRNTDLLRIELDSAPDVFDDGLPPARVAEHLHTLIRHGLAVPRRPASRIPLLD
                     SAGRADALLAAHGPAVPLPEGATVHGLFAEQARRTPDRVAVSGAGSTTYAALDTHAGQV
                     ADALRRAGVAAEDRVAVLVERGPALPAALLGTLRTGAGYVPVDAEYPAERIAYLLRDSG
                     AAALLVEESTAPLVPPGTAVPVIRVDGLHTPSGTSDGEVSYEAADDVADHVADDNLAYV
                     IYTSGSTGGPKGVMVEHRSVVNRLAWMQRRYPIGPHDVILQKTPATFDVSVWELFWWAA
                     SGAAVAMLPPRAHRDPREILRAVAEHRVTVVHFVPAMLGPFLDMLEDEPASLSEAASLR
                     YVFSSGEALTPGLVHRFNSLFAVLERPPRLVNLYGPTEATVDVSCYDCSDHPAQGGAPV
                     PIGHPVDNTQLYVLGPGDEPQPVGVPGELCIGGVQVARGYLGRPELSRERFTADPFTPG
                     GRLYRTGDLARRTAGGRFEFLGRIDDQVKIRGHRVEPGEVQAALTAVAGVRAAAVVART
                     TPERGTHLVAYWAGEHEISPAQLRTELARSLPDHLIPAFWTRVEALPLTPNGKLDRAAL
                     PAPEHAAEPSRPPRAGAESLLVAVWSQVLGAQVAVHDDFYALGGDSLLALRVQAEAERR
                     GLRFEIRDLMRYPTVAALAEHTRPAGERPALAPFALVAHADRHVRHGAQDAFPLSRLQL
                     GMVYHSLRSASADAEGPGPQDLGPYRDVFHYGLRMPWDEERLRRAYDRLTARHPALRSV
                     ISLTGFGEPLQIVLHQAPGGLECRDLRAASEAEADAELARYVEERRHHRYDFEAGPLHQ
                     LRAHARADRVDLVLGFHHAVLDGGSVAGLMGELLQDYLHRLGADVDAAGAAPPPSPALY
                     VAAELEALRSTDARAYWEERLQGATPLQLPRFATAEPPRGTGRFTRLTPLPDGLHDRLR
                     DFGRTHGLPLKSALFAAYTLTLRLLSGQDDVTTGLVVHGRSELPGADRTAGLFLNTLPV
                     RVDAAPRSLVDHVRDVFRHEQDSYAHRHYPLHRIEEDFGGPLLDTAFNYVHLHALEALR
                     RLPGLDLLSVRTWEESGMSLLVSAVVHPVDGNLWLSLDCDGRAFTTGQAELFTDTCLRV
                     LERLVTHPDEQADLAFLTPEPDARPAEDAGAAYTDLARVVHARAEETPDAIALAFEDQR
                     WTYRRLDRTSDVIARRLLADGAFPGARVGIAMDRCPEYVAAVLGVLRAGCAVAPLDPGY
                     PAARISAMIEAVRPFTVVTQRHHAGLLGDVPQLAAESVPAPSATDSFEPPPIRPADTCY
                     VLCTSGSTGVPKAVAMPHRALSSLVDWQNRIPSGAVTGPTLQFSALGFDVHLQEIFATL
                     CAGAPLQLVSEEQRLDFPALLRLLDRERVERLFLPYVALQQLAETSVALGLVPRALRVI
                     ISAGEQLRVTDEIRRLCAALPTPGVLLENQYGPTETHIVTGFTMTGDPARYPALPPIGT
                     AVDGSEVTVLDRALRPLPVGATGEIYAMGACLADGYEGQPDLTAERFVELPARPGHPAG
                     PRAYRTGDLGYTLPGGDIVCLGRTDTQVKIRGFRIEPAEVELHLTATPSARAAGVSEAA
                     VVARGEGPTSFLAAFLVADPGSVDLDATRRELRAQLPGHMVPSHLECLPVLPRTPSGKR
                     DDAALRRIPLTRRALTSAAPSDALERRLAEIAAETLQLPAVGAHDDLFQLGATSLTVMR
                     LVIRIEQALGTAVPVSALITAPTIAELAAYLRAGEAGSAAVQGPLIALRNSGTRRPVFL
                     AHPTGGNVLCYLPLARALPPDQPLYGFQAAGLAPGTAPLRTVPEIARSYVAAMRAVQPH
                     GPYTLGGWSFGGHIAFEMAAQLRAAGEEVAEVLLIDSDALDHSTGRPEVDGLSLMTWFF
                     WELLWLDRGGDVPADAFRALRDEDDAYASVRELAVRTGMLAAHDADTSLRRVFEMFRAN
                     WDALIDWRPAPTDQDLVLIRAQGSLPDVLKPVHDRAGSLYHEPANGWRRLTTGHVRVVD
                     VPGDHMQIVQDPYVRHVAAVLTEATGADTAERRPTPSAHITGRY"
     aSDomain        20052..20960
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS01290_Condensation_Start
                     er.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="1.10E-58"
                     /label="IE308_RS01290_Condensation_Starter.1"
                     /locus_tag="IE308_RS01290"
                     /protein_end="320"
                     /protein_start="17"
                     /score="190.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIVADG"
                     /tool="antismash"
                     /translation="ERFPLSAHQRDIWTVCRSGEESAQFTIAGHQRLHGPVDIDVLAGS
                     LDRVTRRHDALLTRFGEADGVPYQWVGHEPLPVEVLDLSGAPDPAAACRRAVDAALTVP
                     LRLRTDRLFHPMLLRQDAETVHIVLRAHHIVADGYALDLFLTRVLAHYESHIRDGSRPG
                     APDEPSTLGAPSAPGDPCPSYRSFVDEDLAYRGSPEHQADQDFFRERLNGAVPALFARR
                     PAPPGGDRRVSVTLEPEEVAAIRATGTSVFSYVAAALGTYLARLHGTDSAMLGVAFLNR
                     RGPRHAATVGHFATTLPLLVPV"
     aSModule        20052..23207
                     /complete
                     /domains="nrpspksdomains_IE308_RS01290_Condensation_Starter
                     .1"
                     /domains="nrpspksdomains_IE308_RS01290_AMP-binding.1"
                     /domains="nrpspksdomains_IE308_RS01290_PCP.1"
                     /locus_tags="IE308_RS01290"
                     /monomer_pairings="Ser -> Ser"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       20121..20237
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS01290_0001"
                     /evalue="1.70E-09"
                     /label="C2_starter_024-063"
                     /locus_tag="IE308_RS01290"
                     /protein_end="79"
                     /protein_start="40"
                     /score="30.3"
                     /tool="antismash"
                     /translation="QFTIAGHQRLHGPVDIDVLAGSLDRVTRRHDALLTRFGE"
     CDS_motif       20445..20507
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS01290_0002"
                     /evalue="5.50E-06"
                     /label="C3_DCL_135-156"
                     /locus_tag="IE308_RS01290"
                     /protein_end="169"
                     /protein_start="148"
                     /score="19.0"
                     /tool="antismash"
                     /translation="HHIVADGYALDLFLTRVLAHY"
     CDS_motif       20871..20948
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS01290_0003"
                     /evalue="1.60E-04"
                     /label="C5_starter_265-294"
                     /locus_tag="IE308_RS01290"
                     /protein_end="316"
                     /protein_start="290"
                     /score="14.3"
                     /tool="antismash"
                     /translation="LGVAFLNRRGPRHAATVGHFATTLPL"
     misc_feature    20949..20951
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        21456..22706
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS01290_AMP-binding.1"
                     /evalue="4.30E-110"
                     /label="IE308_RS01290_AMP-binding.1"
                     /locus_tag="IE308_RS01290"
                     /protein_end="902"
                     /protein_start="485"
                     /score="360.0"
                     /specificity="substrate consensus: Ser"
                     /tool="antismash"
                     /translation="FAEQARRTPDRVAVSGAGSTTYAALDTHAGQVADALRRAGVAAED
                     RVAVLVERGPALPAALLGTLRTGAGYVPVDAEYPAERIAYLLRDSGAAALLVEESTAPL
                     VPPGTAVPVIRVDGLHTPSGTSDGEVSYEAADDVADHVADDNLAYVIYTSGSTGGPKGV
                     MVEHRSVVNRLAWMQRRYPIGPHDVILQKTPATFDVSVWELFWWAASGAAVAMLPPRAH
                     RDPREILRAVAEHRVTVVHFVPAMLGPFLDMLEDEPASLSEAASLRYVFSSGEALTPGL
                     VHRFNSLFAVLERPPRLVNLYGPTEATVDVSCYDCSDHPAQGGAPVPIGHPVDNTQLYV
                     LGPGDEPQPVGVPGELCIGGVQVARGYLGRPELSRERFTADPFTPGGRLYRTGDLARRT
                     AGGRFEFLGRIDDQVKIR"
     CDS_motif       21897..21956
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS01290_0004"
                     /evalue="1.30E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="IE308_RS01290"
                     /protein_end="652"
                     /protein_start="632"
                     /score="33.1"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGGPKGVMVEH"
     CDS_motif       22359..22382
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS01290_0005"
                     /evalue="1.20E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="IE308_RS01290"
                     /protein_end="794"
                     /protein_start="786"
                     /score="5.7"
                     /tool="antismash"
                     /translation="YGPTEATV"
     CDS_motif       22500..22589
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS01290_0006"
                     /evalue="6.40E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="IE308_RS01290"
                     /protein_end="863"
                     /protein_start="833"
                     /score="53.6"
                     /tool="antismash"
                     /translation="PVGVPGELCIGGVQVARGYLGRPELSRERF"
     CDS_motif       22671..22733
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS01290_0007"
                     /evalue="1.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="IE308_RS01290"
                     /protein_end="911"
                     /protein_start="890"
                     /score="36.6"
                     /tool="antismash"
                     /translation="FLGRIDDQVKIRGHRVEPGEV"
     aSDomain        23019..23207
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS01290_PCP.1"
                     /evalue="1.40E-20"
                     /label="IE308_RS01290_PCP.1"
                     /locus_tag="IE308_RS01290"
                     /protein_end="1069"
                     /protein_start="1006"
                     /score="65.2"
                     /tool="antismash"
                     /translation="ESLLVAVWSQVLGAQVAVHDDFYALGGDSLLALRVQAEAERRGLR
                     FEIRDLMRYPTVAALAEH"
     aSDomain        23289..24218
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS01290_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="4.90E-51"
                     /label="IE308_RS01290_Condensation_DCL.1"
                     /locus_tag="IE308_RS01290"
                     /protein_end="1406"
                     /protein_start="1096"
                     /score="165.5"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHAVLDG"
                     /tool="antismash"
                     /translation="QDAFPLSRLQLGMVYHSLRSASADAEGPGPQDLGPYRDVFHYGLR
                     MPWDEERLRRAYDRLTARHPALRSVISLTGFGEPLQIVLHQAPGGLECRDLRAASEAEA
                     DAELARYVEERRHHRYDFEAGPLHQLRAHARADRVDLVLGFHHAVLDGGSVAGLMGELL
                     QDYLHRLGADVDAAGAAPPPSPALYVAAELEALRSTDARAYWEERLQGATPLQLPRFAT
                     AEPPRGTGRFTRLTPLPDGLHDRLRDFGRTHGLPLKSALFAAYTLTLRLLSGQDDVTTG
                     LVVHGRSELPGADRTAGLFLNTLPVRVDA"
     aSModule        23289..27248
                     /complete
                     /domains="nrpspksdomains_IE308_RS01290_Condensation_DCL.1"
                     /domains="nrpspksdomains_IE308_RS01290_AMP-binding.2"
                     /domains="nrpspksdomains_IE308_RS01290_PCP.2"
                     /domains="nrpspksdomains_IE308_RS01290_Thioesterase.1"
                     /final_module
                     /locus_tags="IE308_RS01290"
                     /monomer_pairings="Pro -> Pro"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       23406..23498
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS01290_0008"
                     /evalue="8.20E-07"
                     /label="C2_DCL_024-062"
                     /locus_tag="IE308_RS01290"
                     /protein_end="1166"
                     /protein_start="1135"
                     /score="21.3"
                     /tool="antismash"
                     /translation="FHYGLRMPWDEERLRRAYDRLTARHPALRSV"
     CDS_motif       23721..23780
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS01290_0009"
                     /evalue="5.50E-04"
                     /label="C3_LCL_132-143"
                     /locus_tag="IE308_RS01290"
                     /protein_end="1260"
                     /protein_start="1240"
                     /score="12.7"
                     /tool="antismash"
                     /translation="FHHAVLDGGSVAGLMGELLQ"
     CDS_motif       24117..24209
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS01290_0010"
                     /evalue="1.70E-08"
                     /label="C5_DCL_263-294"
                     /locus_tag="IE308_RS01290"
                     /protein_end="1403"
                     /protein_start="1372"
                     /score="27.0"
                     /tool="antismash"
                     /translation="DVTTGLVVHGRSELPGADRTAGLFLNTLPVR"
     aSDomain        24684..25892
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS01290_AMP-binding.2"
                     /evalue="3.70E-84"
                     /label="IE308_RS01290_AMP-binding.2"
                     /locus_tag="IE308_RS01290"
                     /protein_end="1964"
                     /protein_start="1561"
                     /score="274.6"
                     /specificity="substrate consensus: Pro"
                     /tool="antismash"
                     /translation="ARAEETPDAIALAFEDQRWTYRRLDRTSDVIARRLLADGAFPGAR
                     VGIAMDRCPEYVAAVLGVLRAGCAVAPLDPGYPAARISAMIEAVRPFTVVTQRHHAGLL
                     GDVPQLAAESVPAPSATDSFEPPPIRPADTCYVLCTSGSTGVPKAVAMPHRALSSLVDW
                     QNRIPSGAVTGPTLQFSALGFDVHLQEIFATLCAGAPLQLVSEEQRLDFPALLRLLDRE
                     RVERLFLPYVALQQLAETSVALGLVPRALRVIISAGEQLRVTDEIRRLCAALPTPGVLL
                     ENQYGPTETHIVTGFTMTGDPARYPALPPIGTAVDGSEVTVLDRALRPLPVGATGEIYA
                     MGACLADGYEGQPDLTAERFVELPARPGHPAGPRAYRTGDLGYTLPGGDIVCLGRTDTQ
                     VKIR"
     CDS_motif       25086..25145
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS01290_0011"
                     /evalue="2.80E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="IE308_RS01290"
                     /protein_end="1715"
                     /protein_start="1695"
                     /score="23.0"
                     /tool="antismash"
                     /translation="CYVLCTSGSTGVPKAVAMPH"
     CDS_motif       25533..25565
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS01290_0012"
                     /evalue="6.00E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="IE308_RS01290"
                     /protein_end="1855"
                     /protein_start="1844"
                     /score="6.5"
                     /tool="antismash"
                     /translation="QYGPTETHIVT"
     CDS_motif       25674..25763
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS01290_0013"
                     /evalue="2.60E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="IE308_RS01290"
                     /protein_end="1921"
                     /protein_start="1891"
                     /score="35.7"
                     /tool="antismash"
                     /translation="PVGATGEIYAMGACLADGYEGQPDLTAERF"
     CDS_motif       25857..25922
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS01290_0014"
                     /evalue="4.80E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="IE308_RS01290"
                     /protein_end="1974"
                     /protein_start="1952"
                     /score="34.6"
                     /tool="antismash"
                     /translation="CLGRTDTQVKIRGFRIEPAEVE"
     aSDomain        26226..26429
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS01290_PCP.2"
                     /evalue="1.30E-20"
                     /label="IE308_RS01290_PCP.2"
                     /locus_tag="IE308_RS01290"
                     /protein_end="2143"
                     /protein_start="2075"
                     /score="65.4"
                     /tool="antismash"
                     /translation="ERRLAEIAAETLQLPAVGAHDDLFQLGATSLTVMRLVIRIEQALG
                     TAVPVSALITAPTIAELAAYLRA"
     aSDomain        26493..27248
                     /ASF="active site serine present: True"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS01290_Thioesterase.1"
                     /evalue="2.40E-39"
                     /label="IE308_RS01290_Thioesterase.1"
                     /locus_tag="IE308_RS01290"
                     /protein_end="2416"
                     /protein_start="2164"
                     /score="128.0"
                     /tool="antismash"
                     /translation="RPVFLAHPTGGNVLCYLPLARALPPDQPLYGFQAAGLAPGTAPLR
                     TVPEIARSYVAAMRAVQPHGPYTLGGWSFGGHIAFEMAAQLRAAGEEVAEVLLIDSDAL
                     DHSTGRPEVDGLSLMTWFFWELLWLDRGGDVPADAFRALRDEDDAYASVRELAVRTGML
                     AAHDADTSLRRVFEMFRANWDALIDWRPAPTDQDLVLIRAQGSLPDVLKPVHDRAGSLY
                     HEPANGWRRLTTGHVRVVDVPGDHMQIVQD"
     CDS_motif       26676..26750
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS01290_0015"
                     /evalue="4.10E-16"
                     /label="NRPS-te1"
                     /locus_tag="IE308_RS01290"
                     /protein_end="2250"
                     /protein_start="2225"
                     /score="51.1"
                     /tool="antismash"
                     /translation="QPHGPYTLGGWSFGGHIAFEMAAQL"
     gene            27352..28572
                     /locus_tag="IE308_RS01295"
                     /old_locus_tag="GCM10018783_02840"
     CDS             27352..28572
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003960768.1"
                     /locus_tag="IE308_RS01295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02840"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_190216211.1"
                     /transl_table=11
                     /translation="MAGGAVGKKALVIGAGIGGLAAAVALRRIGMDVEIYERAPALKPA
                     GFGISVGANAIRALATLGLDLGLARRGQVVEQMKFMTPTGRPLFDLPHARVDREAGAPT
                     ICLYRGDLQEALWEAAGDTPLTLGATALGYETSDDGVRVRFIDGSEAYGDVLVGADGIR
                     SVIRGQVAGTGPSAPRYGGFLCWLAITEFAHPKFPTGFSGHYWGAGRRFGIHDVGHGRF
                     YWWGSLNVPERAARTHTVDKAEILRTYAGWADEVTAVVRATPQSAIMATPCQDRPFLDQ
                     WGDGRVTLLGDAAHPMLPSLAQGGSSSIEDAVVLAGQLNAADRIGGLTAALRSYEDVQR
                     DRTRTMVEVSRSMARLEQLEHPAARLLRDSAARVMPSAVLAGLLRRTLIYPGADQPVAV
                     PELGGHS"
     gene            28569..28982
                     /locus_tag="IE308_RS01300"
                     /old_locus_tag="GCM10018783_02850"
     CDS             28569..28982
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019473.5"
                     /locus_tag="IE308_RS01300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02850"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_190216212.1"
                     /transl_table=11
                     /translation="MNSPANGTKATVERYLRAIADRDAATVLELLADDVEFRIAGDHPV
                     SGTWKGRDAVVGGFLLPLGELFDPDAGYTIEVRSMIADGEQVAVECLSRSVTKDKVPYE
                     NAIVSVYTVADGRITRMHEYFDTAYFTKTLAAR"
     gene            28979..29728
                     /locus_tag="IE308_RS01305"
                     /old_locus_tag="GCM10018783_02860"
     CDS             28979..29728
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143994.1"
                     /locus_tag="IE308_RS01305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02860"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_190216213.1"
                     /transl_table=11
                     /translation="MTGTRLLAAPEPALHPLSAGYLDDFYRDGSGACAIMSVAHFPDEV
                     LAFLQLECLAAFQAAVAERCDAVVELGCFDGRALEVARAAGIPYCGVDVNGTAVAALRE
                     RIRDEGLDAQATTLVGDAQESVRWSAQVPGRRPLIVLPFNLLGNLPDPRRALTGLRALG
                     GTILISVFNEQPRTTAVRRAYYARCVTGLAEPAQGRYGGAVFRGARGFCSESFSAPALH
                     RLLRECGLVIRSQTANRLGRSLAVRGA"
     gene            29815..31077
                     /locus_tag="IE308_RS01310"
                     /old_locus_tag="GCM10018783_02870"
     CDS             29815..31077
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.5"
                     /locus_tag="IE308_RS01310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02870"
                     /product="cytochrome P450"
                     /protein_id="WP_190216214.1"
                     /sec_met_domain="p450 (E-value: 7.4e-19, bitscore: 64.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTNPSEAGVLHPADAELFRLFSPEGQRDPFPSYARLRALAPVHV
                     SEALGGAFVTGYDAACAVLSGEKFGTVGAEWFDKNQPGWRDSPLLVSVFSSLAGANSPD
                     HTRLRRLVARAFNVRQIEQVRPYTAQLTEQALDAMAERAASGEAPDIPSQLALPVTMGT
                     IARLVGVPPEDLGPFDTWIRKAGVVFEMSVPPEVLAEADAAYTHVLDYFTALVAERRKS
                     PDDDLLSALIAVRDADGDRLGAQELVDLLAFVFGSGFETTAGLIGNTVVTLASHPDQMA
                     ALRTVLSTAPDKLGPVIDELGRFDGSVQATRRMALEDVEVGGVTIPAGTATIVFLGGAN
                     RDPARFPDPDRLDLHRTDARPLNMGLGVHYCLGAALARLEMEEVLRRLYGRHPSLRLAD
                     TPVRTPGLQLYRYESIPVVLN"
     gene            complement(31213..31410)
                     /locus_tag="IE308_RS01315"
                     /old_locus_tag="GCM10018783_02880"
     CDS             complement(31213..31410)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669059.1"
                     /locus_tag="IE308_RS01315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02880"
                     /product="hypothetical protein"
                     /protein_id="WP_110637451.1"
                     /transl_table=11
                     /translation="MNTEDTGDAAAAAARHARFGRLPERIRFEEMTEGAEAGPSGGAHA
                     AYDPEGAWKYYSCLALDLGL"
     gene            complement(31542..32494)
                     /locus_tag="IE308_RS01320"
                     /pseudo=""
     CDS             complement(31542..32494)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014668762.1"
                     /locus_tag="IE308_RS01320"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="aldehyde dehydrogenase family protein"
                     /pseudo=""
                     /sec_met_domain="Aldedh (E-value: 1.3e-37, bitscore: 126.1,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGRDPQLLDIVSPHDRSVIARAAQAQPHDIDRAVAAARESFDEG
                     MWRLTPPAERIAVLRRFNALREENAERIAELISLENGSAGWFARAGRPGLTRQANAYLK
                     VAEEFGWEETLAPSDPASPVRGVVRREPVNVVAAVIPWNSPFSSATSKIIPALVTGNSV
                     ILKVSPENSPSMGFLAELLEEGARLVTGGPQIPEGLEKGNYVTPTVFADVDNSRRIAQE
                     DTFGPVLVVIAYDDEDDAMRIANDSEYGLSGGVWSADEERAPGRGPSRPYRHRHRQRCL
                     RRLLRAVRRLQGQRNRPASTARSVSAPTPSTRPSRF"
     gene            32692..33765
                     /locus_tag="IE308_RS01325"
                     /old_locus_tag="GCM10018783_02910"
     CDS             32692..33765
                     /NRPS_PKS="Domain: Abhydrolase_1 (82-339). E-value:
                     4.4e-23. Score: 74.1. Matches aSDomain:
                     nrpspksdomains_IE308_RS01325_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521666.1"
                     /locus_tag="IE308_RS01325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02910"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_190216215.1"
                     /sec_met_domain="PF00561 (E-value: 5.1e-22, bitscore: 75.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINRRTFSKAVGMGTGAAAVALTGLQGQASAASANTAAQPSGGAA
                     PTVPAVTPGTHTAFPTLKRVKAGVLDVGYAELGPHHGPAVICLHGWPYDIHSYVDVAPL
                     LADLGYRVIVPYLRGHGTTRFLSSRTPRTAEQSAIALDIIALMDALKIDKAVLAGFDWG
                     SRTGDIIAALWPDRVKALVSTSGYVITNRKAQLAPAAPAVEHNWWYQWYFATERGKKAM
                     EDPDERLALCRYVWTLVSPNWDFDDATYQRTAQAFLNPDYAAIVLFNYRWRIGLIDGEP
                     RYDRYEQQLSAQPSIGVPTITLDPALDPFTPPGDGSSYRSHFTGPYEHRTIADIGHNLP
                     QEAPTVFAQAVVDADHL"
     aSDomain        32938..33708
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS01325_Abhydrolase_1.1"
                     /evalue="4.40E-23"
                     /label="IE308_RS01325_Abhydrolase_1.1"
                     /locus_tag="IE308_RS01325"
                     /protein_end="339"
                     /protein_start="82"
                     /score="74.1"
                     /tool="antismash"
                     /translation="PAVICLHGWPYDIHSYVDVAPLLADLGYRVIVPYLRGHGTTRFLS
                     SRTPRTAEQSAIALDIIALMDALKIDKAVLAGFDWGSRTGDIIAALWPDRVKALVSTSG
                     YVITNRKAQLAPAAPAVEHNWWYQWYFATERGKKAMEDPDERLALCRYVWTLVSPNWDF
                     DDATYQRTAQAFLNPDYAAIVLFNYRWRIGLIDGEPRYDRYEQQLSAQPSIGVPTITLD
                     PALDPFTPPGDGSSYRSHFTGPYEHRTIADIGHNL"
     gene            33903..34760
                     /locus_tag="IE308_RS01330"
                     /old_locus_tag="GCM10018783_02920"
     CDS             33903..34760
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020139611.1"
                     /locus_tag="IE308_RS01330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02920"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_190216216.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 7.1e-19, bitscore:
                     66.0, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 5.2e-06, bitscore: 23.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSIKGGRKRVVTGAVSTLTAGLALGAFALSGTADGATDAAAAPG
                     EPHVKPTVVLEHGAFADGSSWNGVIADLRADGYPVVAAANPLRGPAADAAALRTVLDHI
                     KGPKILVGHSYGGSVISEAAAGDPDVKALVYVAAFLPAPGETALELTGKFPGSTLPDAL
                     DPVTYRQADGSTATDLYIQQDKFRHQFAADVPAGQAALMAAEQRPIAQAALEEKATVAA
                     WKTKPSWDIVTTEDLNIPAAVQRFMAQRAHAHTTEVAASHSVAVSHPHLVADVIERAAR
                     ATAR"
     gene            34884..35753
                     /locus_tag="IE308_RS01335"
                     /old_locus_tag="GCM10018783_02930"
     CDS             34884..35753
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015654989.1"
                     /locus_tag="IE308_RS01335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02930"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_190216217.1"
                     /transl_table=11
                     /translation="MTSHAHLGAFLKARRAQLRPEECGLPEAGSGRRVAGLRREEVARL
                     AAISVDYYTRLEQGRVRASAPVLATLARALRLDEDQQSYLYELAGRSDDRPRRRRPAQR
                     LRPAMRRLLGQLTHTPALVLGRHLDILAWNQAAVALYTDFSAVPPDRRNYVHLLFTDPA
                     LRGMHRDWEHDARDAVAALRMEAAADPDDPRLAGLVGELITRAPGFGTWWAEHRVVTAA
                     YGTKQYRHPLVGDLTLDCDTWASPDGSGQRLMVLTAEPGSPSHDALRILTSWTTRQPAL
                     SGDNGGPP"
     gene            <35767..36123
                     /locus_tag="IE308_RS01340"
                     /old_locus_tag="GCM10018783_02940"
                     /pseudo=""
     CDS             <35767..36123
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669033.1"
                     /locus_tag="IE308_RS01340"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02940"
                     /product="TetR family transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="SIEKAIEDARLREAPVAVALHRYVENIIAVNRTWPVDLARMLADE
                     SVRARRDAAVREVDAFLERATDEGLLRRGLPEGWASALLPDLMHLVSRQRPELTPGQAA
                     DIVVDTLLHGLGAS"
     gene            36472..37401
                     /locus_tag="IE308_RS01345"
                     /old_locus_tag="GCM10018783_02950"
     CDS             36472..37401
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669110.1"
                     /locus_tag="IE308_RS01345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02950"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_190216218.1"
                     /transl_table=11
                     /translation="MARTTVTFDSAGIDIAAHLYVPDTPASGPRPALVVGHPGTGVKEQ
                     TSGTYARLMAERGFVTLAFDAAHQGESGGLPRGLEDPAQRVEDFKAAVSFLTTRQEVDA
                     ERIGLLGICASGGYSLAATGGDHRVRAVATVCTADPSRQFRLGAEGGQDPAVFQALLDA
                     AARARTAAARGEDPGVMTMFPETAEEARALGGEHGAEGFEYYCTSRGAHDRSAKVLAWE
                     SIDKLAFYDAFFAVPLIGPRPMLQIIGERAVTAWMAVEAHQRATGPKELYRIPGASHVD
                     LYDKKQYIDLAVEKLTGFFTANLGTTAA"
     misc_feature    complement(37412..37423)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            37571..38038
                     /locus_tag="IE308_RS01350"
                     /old_locus_tag="GCM10018783_02960"
     CDS             37571..38038
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014668974.1"
                     /locus_tag="IE308_RS01350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02960"
                     /product="SsgA family sporulation/cell division regulator"
                     /protein_id="WP_190216219.1"
                     /transl_table=11
                     /translation="MHPDHSPLRARSAPHHVPPLLLEVDQMLDEFTRQAVQAEFRFDPD
                     LPAVINVEFLAERGPTAVWRIGRELLQRGLTAMSGSCDVRMWPTLPGERPSSWLLLESQ
                     EVEALFELPTTELAEWLEATYQVAPAETEMDGLDWDGFLRGLLGGPAVPGE"
     gene            complement(38040..39653)
                     /locus_tag="IE308_RS01355"
                     /old_locus_tag="GCM10018783_02970"
     CDS             complement(38040..39653)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014668978.1"
                     /locus_tag="IE308_RS01355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02970"
                     /product="DUF6351 family protein"
                     /protein_id="WP_190216220.1"
                     /transl_table=11
                     /translation="MRRLLTVLAAGVPLAAAVYLPTAYAEPRTSASTPVGCVATPVKVP
                     AGTRVESVTAVRQEGGTVHGSGILGGTVTGVPAYCEVTVTVTHPGDGDHARIRTWLPVT
                     GWNGRLQALGGAAFSAGDNGTGLAAAVKNGYAATTTDAGVGDVLDVGWALNEQGQVNTA
                     LLENFASRSQHEAAVVGKQVVDAVYGKAAAYSYFTGCSTGGRQGYMEAQRYPDDYDGIL
                     ADAPAVNWDRYVLATLWPQVVMHNEKTYVSGCVLDAFTTAAVKACDTLDGARDGLVNDA
                     SRCDFDPRRLIGTKVLCEGKELTVTAADAAVVHKIWDGPRTASGRKLWAGVPVGADLKG
                     LAGTAADADGNLKGAPFPVPAHWTASWVKKDPSFDVSTLTYGEFTELFRQAVAEYGDIM
                     DTDDPDLSAFRESGGKLLTWQGQADQYIPPQGTVDYRRRVVRETGSARKVDDFYRPFLA
                     PNTDHCGLDGQDGKTDGLAALTAWVEHGKAPRTLPATLVNAEGRQLQRDLCAYPEVSRY
                     RGHGDPSLASSFRCVLPFRR"
     gene            40070..41704
                     /gene="abc-f"
                     /locus_tag="IE308_RS01360"
                     /old_locus_tag="GCM10018783_02990"
     CDS             40070..41704
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="abc-f"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569317.1"
                     /locus_tag="IE308_RS01360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_02990"
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="WP_190216221.1"
                     /transl_table=11
                     /translation="MSDAAVVCSSLSFAWPDDTPVFRDLSFTVATGRTGLVAPNGSGKS
                     TLLKLIAGELKPATGSVTVSGTLGYLPQSLPLTGDLTVGEVLGVAEVIRALDAVESGDV
                     SEEHFTTIGDDWDIEERTRAQLDRLGLAGLALDRSLSTLSGGQVVTLGLAAQLLKRPDV
                     LLLDEPTNNLDAEARHKLYDALSDFTGCLLLVSHDRALLDRMDRIAELGSGELRFYGGN
                     FSEYEEAVRAEREVAEKNVRNAEQELKREKREMQQARERAERRMSNASRNLKNAGLPKI
                     FAGTMKRGAQEAAGRSGQMHASRVSEAKARLDEAGRAVRDEQRLTLELPDTHVPAGRNL
                     FLGEGMQVHHDGRAVFADGGIDLTVRGPERIALTGPNGAGKTTLLRLITGDLTPDSGEI
                     RRNDGRIAYLSQRLDLLDVDRTVAENFAASAPERPEAERMNLLARFLFRGARAHLPVGV
                     LSGGERLRATLACVLCAEPAPHLLLLDEPTNNLDLVSAGQLESALNSYQGAFLVVSHDE
                     RFLAEIGVNRWLRLADGVLQETGAPEV"
     gene            41783..43465
                     /locus_tag="IE308_RS01365"
                     /old_locus_tag="GCM10018783_03000"
     CDS             41783..43465
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014668985.1"
                     /locus_tag="IE308_RS01365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03000"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_190216222.1"
                     /transl_table=11
                     /translation="MPQPALLAHDLVRTLDGRRVLDGISLTAAPARRIGLIGENGVGKS
                     TLLRVLAGVDEPDAGSVSRPADLGFLHQEMPYDADATVGAVLDEALREAREDLAELERL
                     GEELARVPQDDPRHRELLDAYGRRLEQAQDRESWDADRRAALVLDGLGLGTVGHDRTLG
                     SLSGGQRGRLALAALLVRRPSALLLDEPTNHLDDGAAAFLEEQVRALPGTVVVASHDRA
                     FLDAVCTDLVDLDPAVDGPVRFGGNYTAYLGEKRAERERWERRYAEEQQELAELRQAVG
                     VTAHRVAPDRGRTDNEKMGYGHRAGRVQNQISRRVRNAARRLEELERSRVPEPPRPLRF
                     TAGELAARAEEGAEPLVALRNVRVPGRLALDALEISATDRLLVTGGNGAGKSTLLAVLA
                     GRLAAEGEVRRRRRLTVGLLTQDTVFDRPERTVRDTYELSLGPARAEQVPLASLGLLHE
                     ADLDKPVGRLSVGQRRRLALALLVARPPQLLLLDEPTNHLSPRLCDELEEALGTGPGAI
                     AVASHDRWLRRRWQGRELRLEQGVRLDAGNGRRENAGTVRSGA"
     gene            43572..44129
                     /locus_tag="IE308_RS01370"
                     /old_locus_tag="GCM10018783_03010"
     CDS             43572..44129
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521661.1"
                     /locus_tag="IE308_RS01370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03010"
                     /product="ABATE domain-containing protein"
                     /protein_id="WP_190216223.1"
                     /transl_table=11
                     /translation="MNLDHVFVCGHPVLDFAATLRARRSTRFEMFVTPDRLNAWYVESG
                     VVDTITPAEESDVREAVAVREALYRLVTNRRLGEEFDREALAVVNGAARKTPVTPQLTL
                     TGRHNEGTPAQALATVARQAVELLSGPDVPLLKECGNPECTRVYIDRSRGMRRQWCGME
                     SCGNKIKAAAYRARKKTVPASA"
     gene            complement(44220..44822)
                     /locus_tag="IE308_RS01375"
                     /old_locus_tag="GCM10018783_03020"
     CDS             complement(44220..44822)
                     /GO_function="GO:0070273 - phosphatidylinositol-4-phosphate
                     binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014668996.1"
                     /locus_tag="IE308_RS01375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03020"
                     /product="GPP34 family phosphoprotein"
                     /protein_id="WP_190216224.1"
                     /transl_table=11
                     /translation="MTTARDLALVALGRPADRPVEQGNLSLALAGAEVIDLLEIEALTL
                     NGDRVVPGLPVATGDRLLDEAVATLAGHGSHETVEDWLWRRGRDLAAAYVDDLQRSGLF
                     TRPRRHGLQPWRGRSVLADSPERTRAEERSASGEPVLTALIDAAVVGDAPDETPETPTG
                     DAVTTVLAAVGDAVTRLEALRLRRDVESAAFDNVWRG"
     gene            complement(44887..45066)
                     /locus_tag="IE308_RS01380"
                     /old_locus_tag="GCM10018783_03030"
     CDS             complement(44887..45066)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE308_RS01380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10018783_03030"
                     /product="hypothetical protein"
                     /protein_id="WP_190216225.1"
                     /transl_table=11
                     /translation="MTDIVDRRAHDRAPARSRERRAGTPQAPQPPARPDAQQVWSWSMS
                     AVLSGYGPAASDFL"
     gene            complement(45256..45684)
                     /locus_tag="IE308_RS01385"
                     /old_locus_tag="GCM10018783_03040"
     CDS             complement(45256..45684)
                     /GO_function="GO:0004601 - peroxidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669000.1"
                     /locus_tag="IE308_RS01385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03040"
                     /product="Ohr family peroxiredoxin"
                     /protein_id="WP_110635423.1"
                     /transl_table=11
                     /translation="MAVSYTAVVDVDGEGRNGGHVRSSDGLLETGLALPKELGGAGTAT
                     NPEQLLAAGWAACFLGALRRAATTRKIRLTSTSITAEITLTHGDDGEFSLSAVLSPVLG
                     GVDQATAEELAQAAHQICPYSKATRDNVPVVLNATAAA"
     gene            46003..46809
                     /locus_tag="IE308_RS01390"
                     /old_locus_tag="GCM10018783_03050"
     CDS             46003..46809
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (4-242). E-value: 1.1e-08.
                     Score: 26.9. Matches aSDomain:
                     nrpspksdomains_IE308_RS01390_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569335.1"
                     /locus_tag="IE308_RS01390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018783_03050"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_190216226.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.2e-14, bitscore:
                     51.4, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERTPVVFIHGAWLHALSWEPWVARFAGRGFLAVAPGWPGEAAAV
                     ADVRASPEPLSRIGLDALTDHYAEFVRSFDTAPVIVGHSVGGLIAQHLIAADVGRAAVA
                     IAPAPVNDIPLPASPGRLLRRDRCDPADELVPLSPEQFHRAIANTLEAEESGRLYDRYV
                     VPAPRRLLADLGCADAPRSPRAAADVGNAGRGPLLLISGQEDRLVPDEATRAVYKQYGD
                     TTAVTDLKQFADRAHSLVIDSGWRFVADYVLGWLDEHGIRAHQPEE"
     aSDomain        46015..46728
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE308_RS01390_Abhydrolase_1.1"
                     /evalue="1.10E-08"
                     /label="IE308_RS01390_Abhydrolase_1.1"
                     /locus_tag="IE308_RS01390"
                     /protein_end="242"
                     /protein_start="4"
                     /score="26.9"
                     /tool="antismash"
                     /translation="PVVFIHGAWLHALSWEPWVARFAGRGFLAVAPGWPGEAAAVADVR
                     ASPEPLSRIGLDALTDHYAEFVRSFDTAPVIVGHSVGGLIAQHLIAADVGRAAVAIAPA
                     PVNDIPLPASPGRLLRRDRCDPADELVPLSPEQFHRAIANTLEAEESGRLYDRYVVPAP
                     RRLLADLGCADAPRSPRAAADVGNAGRGPLLLISGQEDRLVPDEATRAVYKQYGDTTAV
                     TDLKQFADRAHSLVID"
     CDS_motif       46240..46275
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE308_RS01390_0001"
                     /evalue="4.70E-04"
                     /label="NRPS-te1"
                     /locus_tag="IE308_RS01390"
                     /protein_end="91"
                     /protein_start="79"
                     /score="12.8"
                     /tool="antismash"
                     /translation="IVGHSVGGLIAQ"
ORIGIN
        1 gtgaacgccg aggtgttcga cgcctcccgg caccgcatga agcgcggctg gaccatcggc
       61 gcctggttct gcccggtggt gaacctgtgg ttcccgcgcc gcatcgtcgc cgacagctgg
      121 gacgccagcg ctccctgggg ctcgcggtcc gggcacgcgc cggtcaacgc ctggtggacg
      181 gtgtggctcc tcagcctcct cggggaccag tacgccgagc gcagctaccg gcaggccgag
      241 accgcggcag aactgcgtga ggccaccacg acgatgctgt tctccgactg cctcgacatc
      301 gtggccgcgg tcctcgccat cgtggtggtc gtcctcctga cccggatgca ggagcgcaag
      361 gtccgctccg gcgaactgcc ggctcccccg ctcggctgaa accaacggcc tggccctccg
      421 gttccggcct caccgctacc actcccagac aaccaacgcg ccccggtctt ccccggttcc
      481 gcgcgacgcg gccgtagcca tgctgcgctg ttggtcgtcg tgggggtccc gcactcgatc
      541 acaaaatgtc atgcgcgcgg tcgtacgccg tgtcacactc cgccggtgaa tcgcgaacaa
      601 atgtcccggc tcgcccacgc ggaccacccc atcgcggccc cgctcgacga cgacgcagta
      661 cagcgactgc tcgaccgtgc cgtcccgcgt gccgacgccc gcgtcctcga cctcggctgc
      721 ggcggcggag agtggctgct gcgcgccctc ggcgcacacc cgcggctgcg cgccgagggc
      781 gtcgacctct ccgcacgcgc cctggcacac gcccgtgaac gggccaacac cctcggcgtg
      841 gaggagcgtc tcctcctcca ccagacggac gctgcggagt tcagcgcgcc ccacctcttc
      901 gacctggtga tctgcgtcgg tgccacccac gccttccggg gcctgctcgc caccctggac
      961 gccgcccgca aacacctggc ccccggcggg cgcgtcctcg tcggcgacgg tttctgggaa
     1021 cgcgaaccgg ggcctgaggc agtggagatg ctcggcgacc tcgccgatct gccgaccacc
     1081 gtcgagcagg ttgtcaacga cggatggacc ccggtccacg gccacatcag cacccgtcac
     1141 gaactcgacg cctacgagtg ggcctggacg ggctcactgt ccgcctgggc cctcgaccac
     1201 ctcggcgacc cgggcagcgc cgaggctctg gaggcggccg ccgcccatcg cgacgggtgg
     1261 ctgcgcggct accgcgacgc cttcggcttc gtcaccctgg tactgcgcca gacgcccacg
     1321 aacggctgac ctgctggccg gccgatcccc acgacgcgga ctgttggcga accaggcagg
     1381 ggggtgatcc cccaggtggg aacaccctgc ccccctcccc cgtgtccggc cgctgccgcc
     1441 cgctggggcg attgcaacgt accgggcccg tgtcggggta accgactgga cacgtgaagt
     1501 ctgcgagggc agggaagaca tggacggacg ttcgctgcgc gcggtgggct gggcccgctc
     1561 gttgccgctc gacagccaga tcaaaacggc acgtgactgg gcgcgagccc atctggacga
     1621 ggtgggatgg acgagtcacc accccgatac ggccgacgac gtgctgctcg tcgtatcgga
     1681 actggtcacc aacgcgcacg tgcacgggca cagctccgcg cagctggtga tgtcctggga
     1741 cagccagtgc ctgcacatcg cggtgcacga cgcctcgccg gtgctgccga cgccccggga
     1801 gcccgaggaa ctgcggcctg gtgggcgggg catcctcctc atggaggcgc tggccgatcg
     1861 ctgggaggcg cggcgctgtc cgcacggcaa gaccgtcatc gcctgtttcc agccaccggc
     1921 cgacccggag cgctgacgtt tctccgtgga cggagggcgg atgccacgga gtggtgagcg
     1981 gagcggagtg ggccgctccc gcggtgggtg cgggagcggc cggtgggtca ccagcagtgg
     2041 gagctgacgt tgcccacctc gttgcccttg agcaggccgc cccagatgta gttgccgtcc
     2101 gagaggtaga cccacttgtc gtggctgtag ccgttggcgg tgaccatgcc gccctcgcgc
     2161 cagcacacgc cgatgaggtt ctggttcgcc gcgacggtgt aggcgatgcg ccagcccgtc
     2221 gacggcccga tccgcacatt gccctggacc caggtggtga cggtctcgta ctccgcggcc
     2281 acgttcgtcc ggccggcgtg cggggcttgc gccgccgagg ccggagccgc catgccggcg
     2341 gcggccatca cacccaccgc agccgtgatc atgatcttgg tcagccggtg tgaactcgtc
     2401 ctgtgcatcg tctgattccc cctgacgggt tgtggccggg ccaggccctg ggccgggcgg
     2461 tgtcactggt gcgctcagcg tcgcccgcag cagggtgccg agccagcctt tcgggaatcc
     2521 tcgaaaggtc cccgcggccg ccccgccggg ggctcgcaca tcccgtccgg gcagaggcgg
     2581 tgcagcagtc gcacggctcc cgtgccgccg gctcaagagg gcgctcgcgc ggggcactcg
     2641 tcgaccacct gatcgagggc ccgccggccc cggcgtggac gcttgggccg gccgaggacg
     2701 actccggtga ggacgaggac cagtccgcac gtctgctgca gagtcagcag ctccccggcg
     2761 acggctgtgc ccagcagcac gcctgtgacg gggttgagca agccgatcag tccgacggta
     2821 ctggccggca ggtgccgtag gccggtgaac caggcggtga aggcaagcgc ggtggcgaca
     2881 agggcgacgt acgcgaaagc gagcagcacg ggcatgggga gtttcggcgg cgggccctcg
     2941 acggccgcgg cgaccggcag caggaacagc cctccggcgg tgagttgcca ggcggtcgat
     3001 gcgagcaggt cggcaccggt gctccaccgt ttggcgagga ggtggcccag ggacgacacc
     3061 agcacggcgg ccagtgaggc gaggacgccg ggcacgctgg tgccctgcac gcccgtgagg
     3121 agggtgagac agaccccgcc gagcccgacc accgcgcccg cgatgtgcgc gggtgtgggc
     3181 cgctccgaca acagcggcca cgcgatgaac atcatggtca gcggtgacac cgccatgacg
     3241 gtcgaggcga cgctcgtcgg gaggagttgc gaggcggcga agacgaggac gaagaagatg
     3301 ctcacgttga gcaggcccag cactgcagag cgcccccacc acgatccatg cggacgccgc
     3361 ctgctcaggg ccaggaggac cagccccgcc ggcagcgccc gagctgcggc tccgtagagc
     3421 ggacggtcgg ccggcaggaa ctcgtgcgtg acgtagtagt tcgtccccca ggccaccggc
     3481 gcgatcgcgg tcactgccac ccaacggaga ttaccttcca tggaaggtaa tatagcttcc
     3541 atggaagaaa acgtcgtggg cggtgcaggc cggggcgcac aggatcacgt ggcgcgcatc
     3601 caggccgact ggcgccgtga acgccctgcc ctcgatgtcc ggccgcaagg ggtgatcggc
     3661 cggctgcacc gcctggccga ccggctgtcc gatgagctgc gtctcgtcta cggccgctac
     3721 ggcctcagcg agggagagtt cgacgtgctg tgcgcactgc gccgcgccgg tgagcccttc
     3781 gaacgggcgc ccggcgaact ggcggcgcac accatggtca ccaccggcgc gatgacgaag
     3841 aggatcgacc gcctggagcg cgcgggcctc gtcacccgcc gccgttccgc tgacgatcag
     3901 cgtggccgga tcgtcgccct caccggcccc gggcgcgaac tgatcgacca ggcattcacc
     3961 gagcacatgc acaacgaacg ccgcctcgtc gacatgctga cgcctgccga ggccgagtcg
     4021 ctggagacgg tgctcaccgg gtggctctcc cgtatcgagc accgcgccga cggaccggtg
     4081 acccgctccg ggccgcccga gacctaggca gcccgagaca tgagcaccct gcccccttga
     4141 tcgggtcggc cccgacgggt tcaggcaacc tgtgagcccg ctcacgtcct cgtggatgca
     4201 tgtcacaggc gcggaggctg tctcgtctcg ggggcatgac gaacatgacg aagacctccg
     4261 tgctggtcac cggcggcaac aagggactcg ggctcgaaac ggccaggcgg ctcggcgagc
     4321 tcggctggac tgtcttcctc ggctcgcgtg acgagggccg gggccgcgcg gccgccgaca
     4381 agctggccgc cgagggtgtg gatgtggtga tggttcccct cgacgtgacc tcggacgtgt
     4441 cggtcgcggc cgcggtccgg ctggtccgtg cccacaccga ccggctcgac gtgctggtca
     4501 acaacgccgg gaccccgggg cacatcgtgc cgcccgcgga cgcgacggtc gaggagatcc
     4561 accccgtctt cgacacgaac gtgtacgggc ccatcagggt cacgcacgcg ttccttccgc
     4621 tgcttcaggc ggcggatcac ccgcgcgtgg tgatggtgtc cagtgggggt ggctccttca
     4681 gtgtggtgac cgaccccgag cagcccgtct cgaagatgca cgagcttgcc tacagcacct
     4741 ccaaggcggc actgaacatg atcacagtcc gctatgcgca ggcgcttccg gggatcaagt
     4801 tcaacgtcgc cacgcccggc gaggtcgcga accgcaagtt cgccgcgacc gacatgaaca
     4861 accacaccgg cgccctcacg gtcaccgaag gcaccgattc gatcattcgg ctggcgacgc
     4921 tgggtccgga cgggccgacc gggacgttcg tcgaccgtct cggtcccgtc gggtggtagc
     4981 cacggttatg acgccgggcc gatgcgatca gtgcgacgac cgaccatgaa ggcgccgggg
     5041 gtgagcacgg tagaggttcc tccacttctg cgccgccgta cgacagtgaa ttctcctctg
     5101 ggacggtgag gtgctgaatg gttctctgag ctggccggag aaaaacctgc caggaggttc
     5161 ccatgaacac ggccccccga ccgctgttgc ccgacgctca gaaaaccgag cctgcgccga
     5221 taccgagcag cttcgacgcc cacggcgtgg aacccattcc cgagaacggc cgggattcct
     5281 cgccgcggga ccagtggtgg atctgggtgg gcgccaatgt ggcgccgatc aactgggttc
     5341 tcggggcgct gggaattacg ttgggcctca atctggtgga gacgctgatc gtcatttccc
     5401 tggggaacat cgtggggtgc ggcgtcttcg gcctgttcaa catgatgggc caccggaccg
     5461 gcgtcaacca gatggtgctc ggccgcgccg ccttcggacg caagggtgcc gtcgtccccg
     5521 gggtgatgca gggtctgctc accatgggat gggtgggcgt gaacacctgg gtggtcctcg
     5581 acctcgccgt cgccctgctc ggcaaaatcg gcattcacgg aggcgaagga ttgaagtacg
     5641 cggtcgccgg cgtggtgatg gccgcacaac tcggcctggc cgtgttcggc ttctacgcca
     5701 tccgcacgtt cgagcggtgg accgtgccgg cgaccgtact cgtgatggcg gtcatgacgg
     5761 ttctgtccct cacgcagtcg gatctgcact ggacggccgg aaccgcggaa ggcggaaccg
     5821 agaaggtcac ggccgtcacc cagctgctca ccgcgatcgg aatcgggtgg ggaatcagct
     5881 gggtgcccta ctccgcggac tactcgcgat tcgttccggc ccgtttctcc gggcggagcg
     5941 tcttctgggc cacggcgctc ggtatgtacg tgccgaccgt ctggctggcc gctctgggcg
     6001 cctgcctcgc caccaccggg cagggcggtg atccgagcga actcgtcatc agcgccttcg
     6061 gagtgatggc cctgcctgtc cttctgctga tcatgcacgg gcccgtcgcg accaatatcc
     6121 tcaacctcta ctcgtgcgcg ctggccgcgc tgtcggtggg ggtccgggcg gcccgttgga
     6181 aggtgaccct cgtggcgggg gcggtcgcca ccgtggtcct gctggtgttc atgcagtcac
     6241 acagcttcgc cgagtccttc gaccactgga tgacatcgat cctggtctgg atcagcccct
     6301 gggccgccgt catgctgacg gagttcttcg tcctgcgccg cagccggctc gatgtggcgg
     6361 agttgttcga cgaccgtgct ccggcatggc gctggcgcgc gctcctcgcc ctcgcggccg
     6421 gtatcgcggc ggcgtggtcc tggcagtacg gactggtgcc gctcatgcag ggccctctgg
     6481 cccggagcat gcaccacacc gacttctcct ggctgtcggg cgcggtggtc gccggcgggc
     6541 tgcattacct cctcacccgc tccgagaacc gtgccgcccg cgacaggtcc gcccttgccg
     6601 attgacgacg gtagaagccg tcagcaaggc cctctcagga cctcaccaac gcgtcggcct
     6661 caagagccag gaacagatcg accctgcctt cgaacttcat ggggtcgcgg ccggtcagtt
     6721 caccgatgcg ggtgagtcgt ttgcggaggg tgttcacgtg gatgtacagg gcatcggccg
     6781 tggccgcgaa ctgcccttca ttggcgagga aagtgcgcag agtgagttcc agctgggctc
     6841 ctctctgggc atcgtgatcg cgtagcggcg tgaggagcgc atccgcgaag cgctgcacga
     6901 cttgcccgtc caagcgcccc agcagcgcac tgtgggacgg cagttccgcg aaacgggcca
     6961 tacgggccgc ggagctgccc cgcgccagca gttggcacgc ctctcgcgct tccatcagcg
     7021 gaaccttcag cttggtgctg tccccggccg gtccgccgta gcccaacacc actttctgcg
     7081 ccgggagttg cctgtccagg aggcccaaga gccgggtcat cgacgcctca agctcccctt
     7141 ccgtcagacg ccatggaaag agggccacgg tgtcgcggcc acccggcgct acgacggcgg
     7201 gtacaccctc ggacacgaag aaggccatca cagcgttggc cggcacgggt gagaccgccg
     7261 cctctccctc cgcaagggca agggcacaca cggcaagcgg atctccggcc tcgatgccga
     7321 acgtcttcag cctggctgcg aattcccgtg acgctccagc cccggcgaag atcatgtcga
     7381 tcagttcgcc ggcgaagcgc atttcggtgg cttgcacggc gtgcaaccgg gcggtctcca
     7441 tgccgaggaa atgtgcggcc tgttccagcg ctccgcgttc cgcctcgtcg agcgcggcgg
     7501 ccgaccggag gcacacgagc gccgcgtcgg cctctccgaa gactcccacg gggaacagcg
     7561 ccgccgagtc gttcgacagc gtcacctcga gcggaggcgg acggcgagcg actgctcgtg
     7621 ccaccacgac caggtcatcg tcggtgaggc cggctccggc ggagcccaga aggtgcccca
     7681 tgcggtccac caccgcgagc cgcagatcgt gatcccggcg cagtacccgc agcacaccgc
     7741 cggctccggt gcccgagctg atcgcgtcgg ccagtgcgtt gccgcgccgg acggaggcca
     7801 tgagagcgct ctgccgttgt tccgccagtg tccgggcggc ggcctgggac agcgcggtga
     7861 acgggacgtc gaccgacagt tccagcaggg gcatacccgc cttgcggcac gcgtcgatca
     7921 cgtcggccgg agtcgccggc atctcgcgcc gcagcccgaa cacgatcccg gacgccccgg
     7981 cgtcctgtac ccgatgaacg aaggattcgg ccgagtgtcc ggcgatgtgc cacaagccgt
     8041 tggtcatcac cagttcgccg cgccggaggt agggcgaagg gtccggaagc tcggtgttgt
     8101 gcgtccagga gacttcgcag tcgagcgcac cctcggggcc cggcaccagc accgtcagct
     8161 caagatcgcg acgttcgcag agagtccgca gcgtcagcac ggtgtctact ccaccacctt
     8221 ccaagggtgc agccgggcat catctccacc gaccgtacac cgcacccctg ctggagggtt
     8281 ccgcaccacg cacaagccat cgtgccgggc gcccgcctcc tgccggttgt agcttcagac
     8341 accggccggg ccccaacagt ggcggttccc acctcgccct cgtcgcccgg gcgctgcttt
     8401 cttgtctcca tgacgcaagc aacccaggta tgcgcaagca tcgacatccc cgcaggcgaa
     8461 ggcagggccg tccacgtcga tgcggggcaa cgggtaaaga tcatcgacgt cgagggccgg
     8521 caggtcggcg acgtcttcgc cttcgcgcgc ggcgacatcc gcgagtacca ctcggcctca
     8581 cacacccggg cccacgtcaa ccgtctgttc cccgcggtcg gggaacagtt cgtcaccagc
     8641 ctgcgccgcc ccatcctcac cctcgtcgag gactcgtcac ccgggcgcca cgacatgctc
     8701 atcgccgcat gtgacgcagc ccgctacgcg gctctcgccg caccctccga ccacgcctcc
     8761 tgcgcccaga acatgcatga cgccctggcc gcgatagggc tgtccgccga cctggtgcca
     8821 cagccgatca acgtcttcat ggacatcccc gtgagcaacg acggtgctct cacctgggag
     8881 acggcgacgt cccggccagg ggacagcatc accttccagg cggagatgga ctgcgtcctc
     8941 gtggtgtccg cgtgcccgca ggacctcgtg gacatcaacg ccggcgcgcc ttcacctctc
     9001 agactgcaga tagagaacgg agcaaccgca tgaacgccct cgccccccac cctgccctgg
     9061 agcccgtgac cctggccggc gccaagctgg cgaaccggct cgccgtcgct ccgatgaccc
     9121 gagtctctgc ccgtgaggac ggcacgccca ccgaagcgat ggcccgctac tactccgcct
     9181 tcgcctcggg cggcttcggc ctggtcatca ccgagggcac gtacaccgac gaccggcaca
     9241 gccagggcta cttcttccag ccggggatcg tgaccgagtc acatgtccgg gcctggcggg
     9301 ctgtcgccga gtcgatccag gcaggcggcg cccgtgcggt catgcagctg atgcacgcgg
     9361 gcgcgctctc ccagggcaac cggttccgca cggacacggt gggaccgtcg gcggttccgc
     9421 ccaagggtcg gatgatgccc gagtacggcg ggtccggccg atggcccacg cctcgcgcca
     9481 tgaccgacga cgacatcgag acagccgtac agggtttcgt ttccgctgcc gtgaacgcgc
     9541 gggaagccgg gttcgacggt gtcgaggtcc acgcggccaa cggatacctg ctcgaccagt
     9601 tcctgacgga ctacacgaac ctgcgcaccg actcctacgg gggcccggtg gccaaccgga
     9661 tcaggctgac ggcacacgtc accgagcgca tccgggcccg cattcccgac gaggacttct
     9721 ggatcggtgt gcggctctcc cagaccaagg tcaacgactt ccaccaccga tgggccggag
     9781 ccgcggacgc ccgcgtcgtg ttcacgtcgc tggcgaaggc cggcgccagt tacctgcaca
     9841 tcgcgagcga gggccgggac tggatcgaga ccgcacggct cgacagcggc gacacgatca
     9901 ccgctctggc gaagaaggtc accggacttc ccgtgatcgc caacggcggt atgcacgacc
     9961 tcgaccaggc ggcccggctc ctcgaaggag gtcacgccga tctcctctcc ctcggacgag
    10021 gagccctggc caaccccgat ctcccgaacc gggtggccgg cggacacgac ctggacgcgt
    10081 tcgaccatgc catgctccag ccgcgagcct cgctggacaa tgccgaacag tggcggcgtc
    10141 ggaacatgag cgcctgagca agccacccac cccacttcac cggccggcac cgctgtgccg
    10201 gccgggccga ggagccgaag catggaccat tcctggcgcg gccgggccgc cgccgtcgca
    10261 acgctgacct tcgacgtgga cgcggaggca ccgatcctcg cgcacggggc gcactacgcc
    10321 actcatgcgt cgaccatgtc ccaccagtcc tacgggccgg acgtcggcgt accgagaatt
    10381 ctcgacctgc tcgacgagac cggcgttccc gcgacgttct tcgtgccggg ctgggtggcg
    10441 gaacagcgcc cggggctcgc cgcttccatc gtcgaacgcg gtcacgaggt cgcgcaccac
    10501 tcctacagtc atcgtccgcc gacggagatg accgccgacg aggaacgtgc ggacttcgag
    10561 cgtgccatgg aagtgttcgc cgcccaggac atcccgatcg ccgggcaccg cgccgccaac
    10621 tggtcgtcga cgtggctgac ctcgtccctg gtggcggagt acggcttgct ctacgactcc
    10681 tccctcatgg gcgacgaccg cccctacgcc ctgcggaccg aggcgggcac gatcgtggag
    10741 ctgcccgtgc actggtccct cgacgactgg gagcagtacg ccttcctgcc cgcaccgcac
    10801 atcgggtccg tgatcgagtc cccgcgcaag gtgctggaga tgtggacgga cgagctggac
    10861 gccatgaggc actacggctg cttgttcaac ctcaccaacc atccgttcct gaccggccgt
    10921 ccctcacggg ccgtggccct gcgcaagctc atcgagcacg cgcgggaacg cggcgacgtg
    10981 cacttcgctc gctgctcgga cgtcgcacgc gccgcgcgag ccgatacatc gcttcccctg
    11041 cggagcccgg ttccgcccaa gccggccgat tgatcaccga gctccagcga ggccacacca
    11101 tgagtgagat cgaagcactg gccgcggcac tgcgcgccgg cgagacgacc gccgaagcac
    11161 tcgcccggcg cagccttgct cgcatcgcgg accggaacgg cgaactcggt gccttcgcct
    11221 tcgtcgacca cgagggggcg gcaagtgccg cgcgccgtgc ggacgatgag ctgcgcaacg
    11281 gcatcgaccg cggaccgctg cacggcattc cggtggcggt gaaggacctc atcgatgtca
    11341 aggggctgcc cgcaacgcgg ggttccgctc acttcgccgg ccaccgggcc gccgacgatg
    11401 cgacgtgcgt acggcgtctg cggtcggccg gagcggtgat catcggcacc accgtcaccc
    11461 acgaattcgg ctacggcccc accggcgacc gaggtcggca cggtccggcc agaaatcccc
    11521 gcgacccgcg ccgcatggcc ggtggctcca gcggcggcag cgcggcggcc gtcgcctcgc
    11581 acatggtgcc ggtcgcgctg ggcacggaca cgggaggctc cgcgcggatc cccgcggcgc
    11641 tgtgcggcat cgccggttac aaaccggcgt tcggacggct gccgagcgag ggggtgttcc
    11701 ctctcgcgcc cagccttgat cacgtgggtg tgctaggtgt caccgccagg gattgtcgtc
    11761 tggtcgtcga ggcgttggcc cctgagcgtc ccgtgccacg cggtgcccta gcggccgtcg
    11821 cgcggatcgg ctggctcgaa gcggccgccc atgctccagt gacgccggcg gtggcggacg
    11881 tgacacggcg cgcgctgtcg caccacgacg tggcgcaggt ggcgtgcgac gcgctggatg
    11941 ccgtgtggga gacgttcagc gccatccaga acagtgaggc gttcgccacg cacgccgacc
    12001 gggtccgtga gcacccggaa ctcttcgatg ccgaggtcct cgaccggctg cgggaggcat
    12061 ccaagactcc tggatggcgc tatgtccggg cactgcacgc acgtgagacg gcccgacggt
    12121 ccgtcaacgg cgtgttcgat cggttcgacc tgctggcctc gcccaccgtc ggcatcacgg
    12181 cgccacagct cggccggcgg gaggtcacgg tcagcggttc gtcccgctcc gtgcgcagcg
    12241 cgctcctggc cctcacgagt ccgtggaacg ttctgggttt tcccgcgctc agtgttcccg
    12301 ccggctgcgt ggacggcctg cccgtgggcc tgcaactcgt gtgcccaccg gatcgcgagg
    12361 atctgctgtt cgccgtggcc gacggcgttg cggcgtcggt cgccgagacc tgacaggaag
    12421 ggacgggccg ccggaaggtc gcctcaggcg cgttgcaacc agtcgcggtc caggcggtcg
    12481 gccagaccgg cggcggtgaa ggcggcctcc agttcgtcgc ggccttcggt gaagtgggcc
    12541 cagctgtcgt gatggacggg tacgacgcgg cgggcgtcga gtatccgggt ggcttcggcg
    12601 gcctgggcgc tgtccaggac gagcgggttg ttgtcgaaga gcatcgggaa gcggggtgcg
    12661 cccgcgaaca ggacggctgt gtccaccggg gcgaagcgtt cggcgatctc ctttacggcg
    12721 tcgagggagg cgttgtcgcc gctgacatag accgtgggca gaccctcgcc ggtgaggacg
    12781 aagccgacga cctggccggt gtacggctcg accgcctcgc gcgggccggg cccgtgcacg
    12841 gcgggcacac ccatgacggt gagggtgccg cccccggggc gctccagttc gaccgtctcc
    12901 cagtcggcca ggcccttcgc ctctttcccg aggcgttggg cgccgccggg ggtggtcagg
    12961 gtgaggggga tgtcggcgag cagggcccgg ccggaggtgt cgaggttgtc ggcgtgctcg
    13021 tcgtgggaga gcaggacgac gtcgacgcgg ccgaggtcgg cgggggtggc ggtggagggg
    13081 gcggtcttgg tcagggtcgg gccggccgag gggtagtcgc cggggccgtc gaacgtcggg
    13141 tcggtcagga agcgcaggcc gccgtactcg aacagggcgg tcggaccgcc gaaggtgcgg
    13201 accgggaacg agtcgccgtt gagctgggac atcacatctc cgcttctcac gaaaaaatgc
    13261 cgcgtttaac gtgaggccag gctaggcggg cgtcacggaa aaacgcaagg gctaccatga
    13321 gaggcatgga tgatgtgccg gccaccgacg cagcgcaggc cgctctgcct ccggctccag
    13381 gtgccgaccg gtaccgttcc ctggatttcg ccgacaccgc cgcgaccctg cccgccggtc
    13441 agagctacga cctgctcgcc gccccggaat ccgccatgcg ctggctcgcc gcccacgagc
    13501 tgaccgcccc ggacgtgcgg ttgtacgagg tgtgcgcccg gcggatgcgc acgctgcggg
    13561 cgcatgtacg cgccttgttc gccgcccgcg tcgacggcac caccccgccc gaggaatcac
    13621 tgcgcgcggt gaacgaggca ctcacggccg tacccaccgc gcccctgctc gcctgggacg
    13681 gcgcccaagg accgcgtcgc attcacgcac accccaccga ccgcgccgtc aaccacgcgc
    13741 tggcgaccct cgcggccgac gccgccgacc tgctcaccgg tcccgacgcc ggcatcctcg
    13801 ccgcctgcgg ctccccgccc tgcgaccggt tcctgttgcg cacgcacggc cggcgccact
    13861 ggtgctccac ccgctgcggc gaccgcgccc gcgccgcccg cgcctacgcc cggcgcagcg
    13921 gcaccccgag ctgacccacc acacgtctcg tgccggccgc ggcccctcgt cgaaggctgc
    13981 ggccggcacg gtcgccctgt gttccgggag gttcagcagg cgccgaggtc ctgccagacg
    14041 ccccactcgc cggtggtgcc gggctcctca cccgtcgtcc accacttggc cttccaggcg
    14101 tggcccttgt gcgagaccct ctggccgccg gtgtacacct tgtccttgac ccagggggcg
    14161 tcggtgcact ggttgccgga gccgccggtg acggtcaggg agtacgtggc cgagtggctg
    14221 cccgaggtgc ccgccccggt cacggtgacc gtgtaggtgc ccgacgccgc ggccgaggtg
    14281 gtggccaggg tgagagtcga gctacccccc gcggtgaccg acgccgggct gagcgaggcg
    14341 gtgacgcccg ccggggttcc gctgacgctg agccgcacac tctgggcgtc acccttggtc
    14401 acggccgtct tgacggtggc agtgacggac tggccggccg tgacggtcgc ggaggccggg
    14461 gtgagcgcga cggagaagtc gttggacggg gtgctggtgc cgtcggtgaa cggcgcgaag
    14521 atgtgcgtga agtcccacgt gttctgctgg atgcccgagc agttgtccgc ggccgcgccg
    14581 cccgggcagc cgccgttgtc ccgctgcagt gcccagaaag acagcgtgtt gatgcccttg
    14641 gcgaccgccc agtcgtacac ggtccgggcg ttggccaggg tgaaggtctc cgccttgccg
    14701 aagtcgtcga cgcccggcat ctcggtaacg ccgaccatgt tccacagctg ggccgccgac
    14761 ttgcccgggt acagctcggc gagcaggtcg tacaggccct gggcggcggt ctgggtgtcc
    14821 tgcgccatgt cgtggggctg gttgtcgtag tagtcgaacg tcatgaggtt gacgacgtcg
    14881 acccgtgtgc cgttggcgac cgcgttgcgc agcagcgcct cgccgttgtc cgcgaggccg
    14941 tgcgtggtgg tcggcagggt gtaggagatc tcgaccttgc gcccgttggc cgccgcccag
    15001 tcctggacca gcttgatggc cttgttgcgg cggtcgatgg cggcggtgtt gtcgagcgag
    15061 tcgacctcga tgtccatgtc gagccgcgag atgtcgtagg tggtgatgac cttctcgtac
    15121 gcggcggcga tctgctgcac gtccgtgcag ctgtcggcga tctcggtccc ggtggtgtcg
    15181 gccgtgtagc ccccgaacga ggggatgacg tcaccgccgg ccgcctggat cgtcttgatg
    15241 tcggcgccga aggacgaggc ggcgatcggc atgctcgtgt cgccgttcca gtacggcgtg
    15301 caggagccct tggtggcggt ctgcaggaac gccatggtca ggtgcttggc gcccgactgg
    15361 gcggagaggg cggcggggct ctcgccggtc catgcttcga agtagggggc gaagacgtgg
    15421 tgcggcaggg gcgtcgcggc ctgggcggtg ccggcacccg tgagggcgag gcccacggcg
    15481 gcggccgcgg tggcggctgc ggcgagggca gcgtggaagg aacgcactcg tctcatgtca
    15541 gtccaggtgt ggggagggaa tggcggatgt ccgcgctggg acggggagtt gccgcctact
    15601 gggatagcgg ccgccgcgag agcgggtcaa tggtctgaac caagaatgga ctagacccct
    15661 tgggagtcgc cgggccccct ttgcctgtac agggcacccg tcggcggact ggaccacgct
    15721 cgaacgttca accagggcgc gtcaccaggg cgtcaccgcc ggctcgccgc cgttctcgct
    15781 ggtgcgcccg ccgcggcatg gtgtttctga aggcatttcc tggacttccg aacagtcaac
    15841 cttgaccggg ccgagcgtgg agctatggtc tagaccttgt cgcggtcaga tgcagatgca
    15901 gacatgaaag ggacctggca tgaacatgaa aagacgtgcg gccgtcacga tcggtgcgct
    15961 ggtcgctccc gtgctcgccg tcagcctccc ggcgagcacg gcaagcgccc acggctgggt
    16021 gacgctgccc acgagccggc agcagcagtg cgccgacggc gtcgtcgact gcggccagat
    16081 caagtacgaa ccgcagagtg tcgagggccc caagggcctg cggagttgca gcggcggtca
    16141 tgccgagtac gccgagctgg acgacgagag caagagctgg aaggtcaccc cggtcggcac
    16201 gacggcgacc ttcacgtggc acaacacggc ccggcacgcc accgcgaact ggcagtactt
    16261 catcggtggc cagaagatcg ccgagttcga cggtcacaac cagcagccgg ccgcggacgt
    16321 gagccagcag gtgaacttcg gcggcttcac gggccgtcag aaggtgctcg ccgtctggaa
    16381 catcgccgac accgcgaacg cgttctactc ctgcgtcgac gtcaacatcg gcggaggcag
    16441 cggcggcggc acgggaggcg gcgacggagg cggcggcacc tgcaccacac cgacctggga
    16501 cgccacacgg gtctaccacg gtggtgacac cgtgtcgtac ggcgggcaca cctggcgcgc
    16561 caagtggtgg gtgacgggcg acaagccggg caccaccggc gagtggggtg tctgggaaga
    16621 cctgggagcc tgctagccgg ccgggcgtgc gaggatctgg cggtcggatc agcacacttc
    16681 gaaggatggc tatgttcgcg atgtccctgg gcgacggggc cgagctgcgg cctttggagc
    16741 cctggcacgc cgaggagttc ctcgcgcaca tggaccgggg ccgcgatttc atcggtgccc
    16801 acatggaact gcccgacctc gccacggact tggtctccgc ccgcgcctat ctccagcgct
    16861 acgccgagaa ggcggcctcc gacaccggcc ggctgtacgg catctggctc gacggcaccc
    16921 tcgtcggtgg cgtctccttc ccgcaattcg acgccgccgc cggtatctgc gaggtcggct
    16981 gctggctgga gcccgctgcc acaggccggg gcctggtcgt acgtgcggca cgggtggtca
    17041 tcgactgggc gttccgtgaa cgcggcatcc accgcgtgca gtggttcgcg tcgccgaaga
    17101 acacgcccag catcaacgtg gccaagcgcc tcggcatgac ccgcgagggc gttctgcgcg
    17161 agacctacct ctaccgtggc gtccgccacg acgcggaggt ctggtcggtg ctggcaccgg
    17221 aatggcaacc cctggccgac tgagcggacg ccggtcccgg cctggccggg ccgcgtcagc
    17281 ggctcggcgg tgtcgggctc ggcggggtga tcccgtcgat caggttggac accagcgcgg
    17341 tcacgaacgc gtccgtgacg ggctcgtccg ggatgagcag ccggtggtag acggcacccc
    17401 acagctggtc gacgagcacc tggacgtcga cgtcgtcgcg gatctcgccc tgctcctggg
    17461 cgcgcctgag ccgctcgccg gccaggcgcc gccgttcgcc ggagtacagg gagcggaacg
    17521 ccacggccag gtcctcgtct gtctgggact ggccgatcag ttcggtcacc acccggccgg
    17581 ccggggtcgc ggtcatgacc cgcgcgaacg cgcgcagctg gctcagcaga tcggcgcgga
    17641 cgtccccggt gtcctcgaac gccagggtct cctctacggc gtggaagtag ccgtccaggg
    17701 ccagcgcgcc cttggacggc caccacttgt acagcgtcgt cttgctgacg ccggacaggc
    17761 gggccacccg ttcgaaggtg aggtcggcga tcccctcccc caggaggatc tcccccacca
    17821 cgcggaagac gtccgcgcgg acctcgtcgg cgggccggcg gccgcgccca cgggccgcgc
    17881 gcccggccac gccctcggcc tgcttcgtca cgatgtctct ccttcgctca tgggaaccgg
    17941 atcagtgtag gaagccgcgc ggcggggcgg ggacgcccgt gcggcggagc cgggctcagg
    18001 accgggtctc cttgacccgg aggaggtcgc cgaagccgag gcgggtgacg aagtcctcct
    18061 gggcgcggcg cagcacctcg ttgacctcct cgaccccggc ctgactgaag tcgacgacgg
    18121 tacggaaggg ccgggtaccg tgcgggaggg ccaggacgcg ggcgatctcc tcggcgacgg
    18181 cccgcgggtg ggcgtcgacg ccgggtggga acagcccttc cgtcgcctgt tcgttgcggg
    18241 ccaccagcgg gtccagctcg gcgtacgcgc gcgtgcgctc gccgtcgccc gcgtgtccgg
    18301 cgttggggaa gtgctcggtg ccctgggtga aggggcccgg catcacgatg gtggtctcga
    18361 tgccgaactg gccgacctcg taggcggtga cctgggccag tgcgtcggcg gcgaacttcg
    18421 acgccacgta ggggcccagg aagggcggga ccacgacgga ggtggtgctg ccgacgtaga
    18481 cgagggtgcc ggagcgacgt gcccgcatgt gcgggagggc ggcccggttg acgcgctgga
    18541 tgccgatcgc gttgatgtcg aggaggcggt ggatgtcgtc cggggtgaac gcctcgacgt
    18601 atccgacgta gaggtgtccg gcgttgtgga cgaccgtgtc gagccgtccg gcctcgtcga
    18661 ggacggtggc gacggccgcc tcggccgagg agtcggactg cacgtcgagt tcgacgacgc
    18721 ggatgtcctg cccctcgctg cgcccgaggt ccaggagttc ccgcgcgcgg ccggcgttgc
    18781 ggccgtggag gtcgcgcatg ctggcgtaga cggtgtggcc ggcggcggcg agcgcgcggg
    18841 ccgtgaggtt gccgatgccg gtggcggcgc cggtgatgag aacgacggat ggcatggtct
    18901 cttccagtcg ggtggcggat gtcggatccc ggatctcggg tgccggactc tgggtggcgg
    18961 gcttcggata cggggtgtcg gatgccggga tctgaacagc ccccggcgct gtccgtcgcg
    19021 cggcggcggt gccgctacgc cggtccgcgt caggcgaggc cgccgttgga gtagaggacc
    19081 tggccgttga cccagcgggc ggggccggcg aggaaggcga ccgactcggc gatgtcgcgc
    19141 ggctcgccca ggcgctccag cggggcggcc ttcgcgaagc ggccgatcgt ctcctcgtcc
    19201 ttgccctcca ggaagagcgg ggtggcgacg gggccggggg cgaccgtgtt gacggtgatg
    19261 tcccggccgc gcagttcccg ggcgaggatc agggtgatgc tctcgacggc cgccttgctc
    19321 gccacgtagg cgccgtaggt ggggagctgg gtgcgggtga cggacgtgga gacgttgatg
    19381 atcgcgccgc cccggcgaac ccggcgggcg gcctgctggg agacgacgaa ggtgccgcgg
    19441 atgttcgtgc ggtgcatgcg gtccaggtcg tccaggttca gctcggcgat cggcgcgagc
    19501 accatgatcc cggcggtgtt gacgacgacg tcgatgccgc cgaaggccgt ctcgacggcg
    19561 tcgaacgcag cctgcatctg ctgctcgtcg gcgacgtcac cgccgaccgc gagggcccgg
    19621 ccgccggacg cggcgatctt ctccacgagg gcttcggcct tgcccttgtt tccggcgtag
    19681 tgcacggcga cggcgaagcc gtccgcgacg agccgctcga cgacggcctc tccgataccg
    19741 ccggtggcac cggtgacgag ggcgacgcgt gcgacacggg gcgaggtgct gacagaggtg
    19801 ctcatggtct tcctccactg gatgtgaacg ctgagtccat ataaacacaa tatgaacgtg
    19861 gcgtccacat aatcgcggcg cggagtgtga gcccggccca cggccgctgg gcgatgtcgg
    19921 gggcggagcc acttcggagg gcctttagtc cgtactgaaa ccgtcttcgc cgaaccgtcg
    19981 gcccggggga aaggcatggc atgggggaca ccaagcacgt gcagggcgag cggagcctgc
    20041 tgcggctgga cgagcgtttc ccgctcagcg cccaccagcg ggacatctgg acggtgtgcc
    20101 gctccggcga ggagtcggcg cagttcacca tcgccggtca ccagcggttg cacgggccgg
    20161 tggacatcga cgtgctggcc gggagcctgg accgcgtgac ccgccggcac gacgcactgc
    20221 tcacccggtt cggtgaggcc gacggcgtcc cctaccagtg ggtcggccac gagccgctgc
    20281 ccgtcgaggt gctcgacctg tccggtgcgc cggacccggc ggcggcctgt cgccgggccg
    20341 tggacgccgc gctcacggtg cccctgcgcc tgcggaccga ccggctgttc cacccgatgc
    20401 tgctgcggca ggacgcggag accgtccaca tcgtcctgcg cgcccaccac atcgtggcgg
    20461 acggctatgc gctcgacctg ttcctgactc gggtgctggc ccactacgag agccatatca
    20521 gggacggttc ccgtcccggc gcacccgatg aacccagcac actcggtgca cccagcgccc
    20581 ccggtgaccc ctgtccgtcg taccgttcct tcgtcgacga ggacctcgcc taccgcggct
    20641 cccccgagca ccaggctgac caggacttct tccgtgagcg cctgaacggc gcggtcccgg
    20701 cgctcttcgc ccggcgcccg gcaccccccg gcggggaccg gcgcgtgtcc gtcaccctgg
    20761 agcccgagga agtggccgcg atccgggcca ccggcacgtc cgtcttctcc tacgtcgccg
    20821 cggcactcgg cacgtacctc gcccgcctgc acggcaccga ctcggcgatg ctcggtgtcg
    20881 cgttcctcaa ccggcgcggc ccgcggcacg ccgccaccgt ggggcacttc gccaccacgc
    20941 tgccgctgtt agtcccggtc gggccggccg acacgctcga atccatggcc ggccgggtcg
    21001 ccgccgacgt ccgcgcgtac cgtcaccacg aacggctcgc actgggagac atgccccggc
    21061 ccgccgcatc cggtgacggg cggcggcagc tcttcgacac caccgtctcc tacctgaacc
    21121 tgcccgagct gcccgacgtc gcgggcctgg tccaggagcg caccggtcac cagcgccgcc
    21181 acgaccagga cgcgctggcg atcctggtcg tccaccaccg gaacacggac ctgctgcgca
    21241 tcgaactcga ctccgcgccg gacgtgttcg acgacggact gcccccggcg cgggtggcgg
    21301 agcatctgca caccctgatc cggcacggcc tggccgtccc ccgccggccc gcgtcccgca
    21361 tcccgctcct ggactccgcc gggcgggcgg acgcgctcct cgccgcgcac gggccggccg
    21421 taccgcttcc cgaaggcgca acggtgcacg gcctgttcgc ggagcaggcc cggcgcacgc
    21481 ccgaccgcgt cgcggtgtca ggtgccggca gcaccacgta cgccgcgctc gacacgcatg
    21541 cgggccaggt ggcggacgcc ctgcggcgcg ccggggtggc ggcggaggac cgggtcgcgg
    21601 tgctcgtcga gcggggcccc gcgctgccgg cggccctgct gggcacgcta cgcaccgggg
    21661 cgggctacgt gcccgtcgac gccgagtacc cggcggagcg catcgcgtac ctgctgcgtg
    21721 acagcggggc cgcggcgcta ctcgtcgagg agtcgaccgc tcccctggtg ccgcccggaa
    21781 ctgccgtgcc ggtgatccgc gtcgacggcc tccacacgcc gagcggcaca tcggacggtg
    21841 aggtgtccta cgaagcggcc gacgacgtgg ccgatcacgt ggccgacgac aacctcgcgt
    21901 acgtcatcta cacctccggt tcgacgggcg gccccaaggg cgtcatggtc gagcaccggt
    21961 ccgtcgtcaa ccgcctcgcg tggatgcagc gccgctaccc gatcggcccg cacgacgtga
    22021 tcctgcagaa gacgccggcc acgttcgacg tgtccgtgtg ggagctgttc tggtgggcgg
    22081 cgtccggcgc ggcggtggcc atgctgccgc ccagggccca ccgcgacccg cgggagattc
    22141 tgcgtgcggt cgccgaacac cgcgtcaccg tggtgcactt cgtgcccgcc atgctcggcc
    22201 cgttcctcga catgctggag gacgagcccg cgtcgctgtc cgaggcggcg tccctgcggt
    22261 acgtgttctc cagcggtgag gcgctcacgc cgggcctggt ccaccggttc aacagcctct
    22321 tcgccgtcct agagcggccc ccgcggctgg tgaacctcta cggtccgacc gaggccaccg
    22381 tcgacgtctc ctgttacgac tgctcggacc accccgcaca gggcggggcg ccggttccga
    22441 tcggccatcc ggtggacaac acccagctgt acgtgctcgg tccgggcgac gagccccaac
    22501 cggtcggtgt tccgggcgag ttgtgcatcg gcggggtcca ggtggcccgc ggctacctgg
    22561 gtcggccgga gctgagccgt gaacggttca ccgccgaccc gttcacgccc ggcggccggc
    22621 tgtaccgcac cggcgacctg gcccgccgga cggcgggcgg ccggttcgag ttcctcggca
    22681 ggatcgacga ccaggtcaag atccgtggac accgggtcga gccgggcgag gtccaggccg
    22741 cgctgacggc cgtcgcgggg gtgcgtgccg cggcggtcgt ggcccggacg acgccggagc
    22801 ggggcaccca tctggtggcg tactgggccg gcgagcatga gatctccccg gcgcagctcc
    22861 gtacggaact ggcccgcagc ctgccggacc acctgatacc cgccttctgg acccgggtcg
    22921 aggcgctgcc gctgacgccg aacgggaagc tggaccgggc cgcgctgccg gcgccggagc
    22981 acgcggcgga gccctcccgg ccgccacgtg cgggcgccga gtccctcctg gtcgccgtct
    23041 ggtcacaggt cctgggcgcc caggtcgcgg tccacgacga cttctacgcc ctgggtgggg
    23101 actccttgct ggccctgcgg gtgcaggccg aggcggaacg gcgcgggctg cggttcgaga
    23161 tccgcgacct gatgcggtac ccgacggtgg ccgcgctggc ggagcacacc cggccggccg
    23221 gcgagcggcc ggcgctcgcg cccttcgcgc tggtcgcgca cgccgaccgg cacgtccggc
    23281 acggagcgca ggacgccttt ccgctcagcc gcctgcagtt gggcatggtc taccacagcc
    23341 ttcgctccgc gtccgcggac gcggagggcc ccggcccgca ggacctgggc ccctaccggg
    23401 acgtcttcca ctacggcctg cggatgccct gggacgagga gcggctgcgc cgcgcctacg
    23461 accggctgac ggcccggcac cccgcgctgc gctccgtcat ctcgctgacc ggcttcggtg
    23521 agccgctcca gatcgtgctc caccaggctc ccggcggact cgaatgccgc gacctgcggg
    23581 cggcgagcga ggccgaggcg gacgccgagc tggcccggta cgtcgaggaa cggcgccacc
    23641 accgctacga cttcgaggcc gggccactgc accaactgcg cgctcacgcc cgggccgacc
    23701 gcgtcgacct cgtcctcggc ttccaccacg ccgtcctgga cggtggcagc gtggccggcc
    23761 tgatgggcga actgctgcag gactatctgc acaggctggg cgcggacgtc gacgccgccg
    23821 gtgccgcgcc cccgccgtca ccggcgctct acgtggccgc ggagctggag gcgctgcgct
    23881 cgacggacgc ccgcgcctat tgggaggaac ggctgcaagg ggccacaccc ctgcaactgc
    23941 cccggttcgc caccgccgag ccgccccgcg gcaccgggcg cttcacccgg ctgacccccc
    24001 tgccggacgg cctgcacgac cggctgcgcg acttcggccg cacccacgga ctgcccctga
    24061 aatcggcgct gttcgcggcg tacaccctga cgcttcggct gctgtccggt caggacgacg
    24121 tgacgacggg cctggtcgtg cacggccgct ccgagctgcc cggcgccgac cgcaccgccg
    24181 ggctgttcct caacaccctg ccggtccggg tcgacgccgc cccgcgcagc ctggtggacc
    24241 acgtccggga cgtcttccgt cacgagcagg acagctacgc gcaccgccat tacccgctcc
    24301 accgcatcga ggaggacttc ggcggcccgc tgctcgacac cgcgttcaac tacgtgcacc
    24361 tgcacgccct ggaagcgctg cggcggctgc ccgggctgga cctgctgtcc gtgcgcacgt
    24421 gggaggagag cgggatgagc ctgctggtca gtgccgtcgt ccaccccgtc gacggcaacc
    24481 tgtggctcag cctggactgc gacgggcgcg ccttcaccac cggccaggcc gaactgttca
    24541 cggacacctg cctgcgggtc ctggagcgcc tcgtcaccca ccccgacgag caggccgacc
    24601 tggccttcct gaccccggag ccggacgcgc ggcccgccga ggacgcgggg gcggcgtaca
    24661 ccgacctggc gcgggtcgtc cacgcccgtg ccgaggagac gcccgacgcg atcgccctcg
    24721 ccttcgagga ccagcgctgg acctaccgcc gcctggaccg gacctcggac gtgatcgccc
    24781 gtcggctgct ggccgacggc gcctttccgg gcgcccgggt cgggatcgcc atggaccgct
    24841 gccctgagta cgtcgcggct gtcctcggcg tgctccgcgc cggatgtgcc gtcgccccgc
    24901 tggaccccgg ctacccggcg gcccgtatct ccgcgatgat cgaggcggtc cggccgttca
    24961 ccgtcgtcac gcagcggcac catgccggat tgctgggcga cgtaccgcag ctcgcggccg
    25021 agtccgtgcc cgccccctcg gccaccgact ccttcgagcc gccaccgatc cgccccgccg
    25081 acacctgcta cgtcctgtgc acctccggtt ccaccggcgt gcccaaagcc gtcgccatgc
    25141 cgcaccgggc tctgtcgagc ctggtcgact ggcagaaccg gatccccagc ggcgcggtga
    25201 ccggccccac gctgcagttc tccgcactgg gcttcgacgt ccacctccag gagatcttcg
    25261 cgacgctgtg cgccggtgcc ccgctgcagc tcgtcagcga ggaacagcgc ctggacttcc
    25321 ccgccctgct gcgcctgctc gaccgcgagc gtgtcgagcg cctcttcctc ccctacgtgg
    25381 ccctgcagca gctcgcggag acctccgtcg cactcggcct ggtgccccgt gcgctccggg
    25441 tgatcatctc ggcgggggaa caactgcggg tcaccgacga gatccgccgc ctgtgcgcgg
    25501 cgctcccgac gcccggcgtc ctcctggaga accagtacgg gcccaccgag acccacatcg
    25561 tcaccggctt caccatgacc ggcgacccgg cccgctatcc cgcgctgccg cccatcggga
    25621 ccgccgtaga cggcagcgag gtcaccgtcc tggaccgcgc gctgcgcccg ctgcccgtcg
    25681 gcgccacggg cgagatctac gccatgggtg cgtgcctggc cgacggttac gagggacagc
    25741 cggacctgac agcggagcgc ttcgtcgaac tccccgcccg gcccggccac cctgccggcc
    25801 cgcgggccta ccgcaccggc gacctcggct acaccctccc cggcggcgac atcgtctgcc
    25861 tcggccgcac ggacacccag gtcaagatcc gcggtttccg catcgaaccg gccgaggtcg
    25921 aactccatct caccgcgaca ccctccgccc gcgccgcggg cgtcagcgag gccgcggtgg
    25981 tggcccgggg cgagggcccg acctcgttcc tggccgcgtt cctcgtcgcc gacccgggca
    26041 gcgtcgacct ggacgcgacc cggcgggagc tgcgcgccca actgccgggc cacatggtcc
    26101 cctcgcacct ggagtgcctg cccgtcctcc cccgcacccc cagcgggaag cgcgacgacg
    26161 ccgccctgcg ccgcatcccg ctcacccgcc gtgcgctcac ctccgccgct ccgtccgacg
    26221 cgctggaacg gcggctggcc gagatcgccg cggagacgct ccaactgccc gcggtgggag
    26281 cccacgacga cctgttccag ctgggtgcga cctccctgac cgtcatgcgc ctggtcatcc
    26341 gcatcgaaca ggccctgggc acggccgttc cggtctcggc cctgatcacg gcgcccacga
    26401 tcgcggaact ggccgcgtac ctcagggccg gcgaggccgg atccgccgcc gtacaaggcc
    26461 ccttgatcgc cctgcggaac tccggaacgc ggcgcccggt gttcctcgcg caccccaccg
    26521 gcggcaacgt gctgtgctac ctgccgctgg cccgggcact cccgcccgac cagccgctct
    26581 acggcttcca ggcggccgga ctcgcgccgg gcaccgcgcc cttgcgcacc gtcccggaga
    26641 tcgcccgcag ttacgtcgcc gcgatgcgcg ctgtccagcc gcacggtccg tacaccctcg
    26701 gcggctggtc cttcggcggg cacatcgcct tcgagatggc cgcccagctg agggccgccg
    26761 gcgaagaggt cgcggaggtg ctcctcatcg actccgacgc cctggaccac agcaccggcc
    26821 gccccgaggt cgacgggctg tccctcatga cctggttctt ctgggaactg ctctggctgg
    26881 accgcggcgg cgacgtgccg gccgacgcgt tccgcgccct gcgcgacgag gacgacgcct
    26941 acgcgagcgt ccgcgaactc gccgtacgca ccggcatgct cgccgcccac gacgccgaca
    27001 cctccctgcg ccgcgtcttc gagatgttcc gcgcgaactg ggacgccctc atcgactggc
    27061 ggcccgcccc caccgaccag gacctcgtcc tgatccgcgc gcaaggttcg ctgcccgacg
    27121 tgctcaaacc cgtgcacgac cgcgccggaa gcctctacca cgaaccggcc aacggctggc
    27181 ggcggctgac cacgggtcac gtccgcgtcg tggacgtgcc gggggaccac atgcagatcg
    27241 tgcaggaccc gtacgtacgc cacgtcgcgg cggtcctcac cgaggcgacc ggcgccgaca
    27301 ccgcggaacg ccgtccgacg ccgtcggctc acatcacagg gaggtactga catggctggt
    27361 ggtgccgtcg ggaagaaggc cctcgtcatc ggcgcgggca tcggcggtct cgccgccgcc
    27421 gtcgcgctgc gccggatcgg catggacgtc gagatctacg agcgggcgcc ggcgctcaag
    27481 cccgccggtt tcggtatctc cgtgggcgcc aacgccatcc gcgcgctggc caccctcggg
    27541 ctcgacctcg gcctggcacg gcgcggccag gtggtcgagc agatgaagtt catgacgccc
    27601 accgggcgcc ctctgttcga cctcccgcac gcccgcgtcg accgcgaggc cggcgccccc
    27661 accatctgcc tgtaccgcgg ggacctgcag gaagcgctgt gggaggccgc gggcgacacc
    27721 cccctcaccc tgggcgcgac cgcgctgggc tacgagacgt cggacgacgg tgtgcgggtc
    27781 cggttcatcg acggcagcga ggcgtacggc gacgtgctcg tcggtgccga cggcatccgt
    27841 tcggtgatcc ggggccaggt cgccggaacc gggccgtccg cccctcgcta cggcggcttc
    27901 ctgtgctggc tggccatcac cgagttcgcc caccccaagt tcccgacggg tttcagcgga
    27961 cactactggg gcgcgggccg ccgcttcggc atccatgacg tggggcacgg acggttctac
    28021 tggtggggca gcctgaacgt gcccgagcgt gccgcccgca cccataccgt cgacaaggcc
    28081 gagatcctgc gcacctacgc gggctgggcc gacgaggtca ccgcggtggt acgcgccaca
    28141 ccccagtccg ccatcatggc cacgccctgc caggaccggc ccttcctgga ccagtggggc
    28201 gacggccgcg tgacgctgct gggcgacgcc gcccacccga tgctgccgag cctggcccag
    28261 ggcggcagct cctccatcga ggacgctgtc gtactggccg ggcagctgaa cgcggccgac
    28321 cggatcggcg gactgaccgc cgcgctgcgc tcgtacgagg acgtccagcg cgaccggacc
    28381 cgcacgatgg tcgaggtctc gcgttccatg gcccgcctgg agcagctgga gcaccccgcc
    28441 gcgcgcctgc tgcgcgacag cgccgcccgc gtcatgccca gcgccgtcct cgcgggactg
    28501 ctgcgcagaa cactcatcta ccccggagcg gaccagccgg ttgccgttcc cgagctcgga
    28561 ggtcactcgt gaacagcccc gcgaacggaa ccaaggccac cgtcgagcgc tacctgcgcg
    28621 cgatcgcgga ccgtgacgcc gccaccgtcc tggaactcct cgccgacgac gtggagttcc
    28681 gcatcgccgg cgaccacccg gtgtccggga cgtggaaggg gcgcgacgcg gtggtgggcg
    28741 gcttcctcct gccgctgggc gagctcttcg acccggacgc cggctacacg atcgaggtgc
    28801 gcagcatgat cgccgacggg gagcaggtcg ccgtcgagtg cctctcccgc tccgtgacga
    28861 aggacaaggt tccctacgag aacgccatcg tgtccgtcta cacggtggcg gacggccgga
    28921 tcacgcgcat gcacgagtac ttcgacaccg cgtacttcac caagacgctg gccgcccgat
    28981 gacaggcacc aggttgctcg ccgccccgga accggcactg caccccctgt ccgccgggta
    29041 cctcgacgac ttctaccggg acggcagcgg cgcctgcgcg atcatgagcg tggcccactt
    29101 ccccgacgag gtcctggcct tcctgcagtt ggagtgtctg gcggcgttcc aggcggcggt
    29161 ggccgagcgg tgcgacgcgg tcgtcgaact cggctgcttc gacgggcggg ccctggaggt
    29221 ggcgagggcc gccgggatcc cgtactgcgg cgtggacgtc aacggcaccg cggtggccgc
    29281 actccgcgag cgcatccgtg acgaaggact cgacgcccag gccaccaccc tggtcggcga
    29341 cgcgcaggag tccgtgcgct ggtcggcgca ggtccccggc cggcgccctc tgatcgtgct
    29401 tccgttcaac ctcctgggga acctccccga cccccggcgc gcgctgacgg ggctgcgtgc
    29461 gctgggcggc accatcctca tctccgtctt caacgagcag ccccgcacca ccgccgtacg
    29521 cagggcctac tacgcccgct gcgtgacagg tctggcggag ccggcccagg gccgttacgg
    29581 cggcgccgtc ttccggggcg cgcggggctt ctgctcggag tcgttcagcg cccccgccct
    29641 ccaccgcctc ctgcgggagt gcggcctggt gatccgctcg cagaccgcca accggctggg
    29701 ccgctccctc gccgtacgcg gggcctgacc gccgtccgcg gggcctgaac cgccgtacgc
    29761 ggggcctgaa ccgctgtccg cgccgcagca cgaccgacac ccgaaggaca cccgatgacc
    29821 acgaacccgt ccgaggcagg cgtgctccac cccgccgacg ccgagctttt ccggctgttc
    29881 tctccggagg ggcagcgcga cccgttcccg agctacgccc ggctgcgcgc cctggcaccc
    29941 gtgcacgtga gcgaggcgct cggcggcgcg ttcgtgaccg ggtacgacgc ggcgtgcgcg
    30001 gtgctgtccg gtgagaagtt cggcacggtg ggcgcggagt ggttcgacaa gaaccaacct
    30061 ggctggcgtg acagtccgct gctggtcagc gtcttctcct cgctggccgg ggcgaactcc
    30121 cccgaccaca cacggctgcg caggctggtc gcgcgggcgt tcaacgtacg gcagatcgag
    30181 caggtcaggc cctacaccgc ccagctgacc gaacaggccc tggacgccat ggccgagcgg
    30241 gccgccagcg gcgaagcccc ggacatcccc tcccagttgg ccctgcccgt gacgatgggg
    30301 accatcgccc gactggtggg cgtgccgccg gaggacctgg gccccttcga cacgtggatc
    30361 cgcaaggccg gcgtggtctt cgagatgtcg gtgccgcctg aggtgctggc cgaggccgac
    30421 gccgcgtaca cccacgtact cgactacttc accgctctgg tcgccgaacg ccggaagtcg
    30481 ccggacgacg acctgttgtc ggcactgatc gcggtacgcg acgcggacgg tgaccggctc
    30541 ggtgcacagg aactggtcga cctgctcgcc ttcgtcttcg ggtcgggatt cgagacgacc
    30601 gccggactga tcggcaacac ggtggtcacg ctcgcctcac acccggacca gatggccgcg
    30661 ctgcgaacgg tcctttccac cgcaccggac aagctggggc cggtgatcga cgaactgggc
    30721 cgcttcgacg gttcggtgca ggccacccgg cggatggcgc tggaggacgt ggaggtcggc
    30781 ggtgtcacga tccccgcagg caccgccacg atcgtcttcc tgggcggcgc caaccgcgat
    30841 cccgcccgct tccccgaccc ggaccgcctc gacctgcacc gcacggacgc ccgccccctg
    30901 aacatgggcc tcggcgtcca ctactgcctg ggcgcggcgc tggcccgcct cgaaatggaa
    30961 gaggtcctgc gccgcctgta cggcaggcat cccagcctgc gcctggcgga cacgccggtc
    31021 cggacgcctg ggctgcagtt gtatcggtat gagtcgattc cggttgtgtt gaactgaggg
    31081 catcggcgcg gggcgagaga cgcgggtgtc cgcggtgcgg gataggtccg ccctacgggg
    31141 tgtgccggca gcgcgtaacc ggctgaacgc cggcatgccg ccgcctgcgg cggggtgcgt
    31201 gccgttgccg ggctagaggc ccaggtcgag ggccagacac gagtagtact tccaggcgcc
    31261 ctcggggtcg taggcggcat gtgccccgcc gctcggcccg gcctccgccc cctcggtcat
    31321 ttcctcgaag cggatgcgct cggggagcct gccgaagcgc gcgtgccggg ccgccgcggc
    31381 ggcggcgtcg ccggtgtctt ccgtgttcat ggccatggtc cactcctccg gtcgtggatg
    31441 gcgttacccc tgtcgggggg actgcctcag cgtgcgccgc acatgcgtca cctgtcaagc
    31501 cggtgacggc aaatcgtcca tggggttcat cgctcgggag gtcaaaccgt gatggtcttg
    31561 tactcggtgt aggtgccgat accgaccgcg ccgtactcgc cggccgattc cgctggcctt
    31621 gaagccgccg aacggcccgt agaaggcgac ggaggcaccg ttgacggtga cggtgccggt
    31681 acggacgcga cgggccacgg ccaggggcgc gctcctcgtc ggcggaccag acaccgccgg
    31741 aaaggccgta ctcggagtcg ttggcgatgc gcatcgcgtc gtcctcgtcg tcgtaggcga
    31801 tgaccaccag aaccgggccg aaggtgtcct cctgcgcgat ccgcctggag ttgtcgacgt
    31861 cggcgaagac ggtgggcgtc acgtagttgc ccttctccag gccctcgggg atctgcgggc
    31921 cgccggtgac caggcgggca ccttcctcca gcagttcggc caggaagccc atgctcggcg
    31981 agttctccgg cgacaccttc aggatcacgg agttcccggt caccagggcc gggatgatct
    32041 tggaggtggc cgatgagaag ggcgagttcc acgggatgac cgcggccacg acgttgaccg
    32101 gctctcggcg caccacgccg cggaccgggg aggccggatc ggagggagcc agggtctctt
    32161 cccacccgaa ctcctccgcc accttcaggt aggcgtttgc ctggcgggtc aggccgggcc
    32221 gcccggcacg cgcgaaccag cccgccgagc cgttctccag ggagatgagc tccgcgattc
    32281 tctccgcgtt ctcctcgcgc agggcgttga accggcgcag cacagcaatc cgctcggccg
    32341 gcggcgtcag ccgccacatg ccctcgtcga aggactcccg ggcggcggcg accgcacggt
    32401 cgatgtcgtg cggttgcgcc tgggcggcgc gcgcgatcac cgaccggtcg tgcggcgaga
    32461 cgatgtcgag caactgcggg tcgcgcccgg acaacgggcc gccacccgcg gcgcgtcacc
    32521 cgtacgacgc cgtcagccga tcgcaccgtc atgtgactga tgtgcctgga ttcgccaccg
    32581 acgagagtga gtggaggcag cccggcccgg acacgcggtg acgcgtcacc tgtttgacag
    32641 gtgacgcact gcgtgcaagg gtcacacgac acgcacaacg gaggagttca gatgatcaac
    32701 aggcgtacct tcagcaaggc cgtgggcatg ggcaccggcg cggccgccgt ggcactgacc
    32761 ggcctgcagg gccaggcgtc cgccgcgtcc gcaaacaccg ccgcgcagcc gtcaggcggg
    32821 gcggctccga ccgtccccgc cgtcacgccc ggcacccaca ccgccttccc cacgctgaag
    32881 cgcgtcaagg cgggcgtcct ggacgtcggt tacgccgagc tcggtccaca ccacggcccg
    32941 gccgtcatct gcctgcacgg ctggccctac gacatccaca gctacgtcga cgtcgccccg
    33001 ctcctcgccg acctgggcta ccgcgtgatc gtcccgtacc tgcgcggcca cggcaccacg
    33061 cgcttcctgt ccagccgtac gccccgcacc gccgagcagt ccgcgatcgc cctcgacatc
    33121 atcgccctga tggacgcgct caagatcgac aaggcggttc tggccggctt cgactggggt
    33181 tcgcgcaccg gcgacatcat cgccgccctg tggcccgacc gcgtcaaggc gctggtctcc
    33241 accagcggtt acgtcatcac gaaccgcaag gcgcagctgg cgcccgccgc tcccgccgtc
    33301 gagcacaact ggtggtacca gtggtacttc gccaccgagc gcggcaagaa ggcgatggag
    33361 gaccccgacg agcgtctcgc cctgtgccgc tacgtgtgga ccctcgtctc ccccaactgg
    33421 gacttcgacg acgccacgta ccagcgcacc gcccaggcct tcctcaaccc ggactacgcc
    33481 gccatcgtcc tgttcaacta ccgctggcgc atcggcctca tcgacggcga accccgctac
    33541 gaccgttacg agcagcagct ctctgcccag ccctcgatcg gcgtccccac catcaccctg
    33601 gacccggccc tggacccctt cacgccgccc ggtgacggct cctcctaccg cagccacttc
    33661 accggcccct acgagcaccg caccatcgcg gacatcggcc acaacctgcc gcaggaggcg
    33721 cccaccgtct tcgcccaggc ggtcgtcgac gccgaccacc tctgagggac cgcgcggcac
    33781 ttcattacct cgtcaccgcc ttgacaggtg acgatcattt ctgacacatt cgtcaccagt
    33841 cagggaggtg acgcttccgg cgaaaccggt cctcacattc gaaaaaccga gaggggtctg
    33901 tcgtggtgag catcaagggt gggcgcaagc gagtggtgac gggtgcggtc tccacgctca
    33961 cggcgggact cgcgctcggc gcgttcgccc tgagcggcac cgctgacggg gcgaccgacg
    34021 cggcggccgc ccccggcgaa ccgcacgtca agccgaccgt cgtcctggaa cacggcgcct
    34081 tcgccgacgg ctccagctgg aacggcgtca tcgccgacct ccgcgccgac ggctaccccg
    34141 tcgtcgccgc ggccaacccg ttgcgaggcc cggccgccga cgccgccgcc ctgcgcacgg
    34201 tcctcgacca catcaagggc ccgaagatcc tcgtcggcca ctcctacggc ggcagcgtca
    34261 tcagcgaggc cgccgccggt gaccccgacg tcaaggcgct ggtctacgtc gccgccttcc
    34321 tcccggcccc cggggagacc gcgctggagc tcaccggcaa gttcccgggc tccacgctcc
    34381 ccgacgccct ggacccggtc acctaccggc aggccgacgg cagcaccgcc accgacctgt
    34441 acatccagca ggacaagttc cgccaccagt tcgccgccga cgtgcccgcg gggcaggccg
    34501 ccctcatggc cgccgagcag cgacccatcg cccaggccgc cctggaggag aaggccaccg
    34561 tcgccgcctg gaagacgaag cccagctggg acatcgtcac caccgaggac ctcaacatcc
    34621 cggcggccgt ccagcgtttc atggcccagc gcgcccacgc ccacaccacc gaggtggccg
    34681 cctcgcactc cgtcgccgtc tcccaccccc acctcgtcgc ggacgtcatc gagcgggccg
    34741 cccgcgccac cgcgcgctga cctgccgtac cagccggaca ggtcccgccg tacagcccga
    34801 cagatcccgc cgtccggtac cgccaccgag cgcggtaccg gacgcagttc cacgcggcac
    34861 tgagccatat gagggtgaac gacatgacct cccacgcgca cctcggcgcc ttcctcaaag
    34921 cacgccgggc gcagctgagg cctgaggagt gcggcctgcc cgaggcgggc tccggccgca
    34981 gggtcgccgg gctgcgccgt gaggaggtcg cccggctcgc cgcgatcagc gtggactact
    35041 acacccgtct cgaacagggc cgcgtccgcg cgtccgcccc cgtcctggcc accctcgccc
    35101 gagccctgcg tctcgacgag gaccagcaga gttacctgta cgagctcgcc ggccggagcg
    35161 acgaccgccc acgccgccgc cggcccgccc agcgtctgcg ccccgccatg cgccgtctgc
    35221 tcggccagct cacccacacc ccggccctgg tgctcggcag gcacctggac atcctggcct
    35281 ggaaccaggc cgcggtcgcc ctctacacgg acttctcagc cgtcccgccc gaccgccgca
    35341 actatgtgca cctgctgttc accgatccag ccctccgcgg catgcaccgg gactgggaac
    35401 acgacgcccg cgacgccgtc gccgccctgc gcatggaagc cgcggccgac ccggacgatc
    35461 cgcgcctggc cggcctcgtc ggggagctga tcacccgggc ccccggcttc ggcacgtggt
    35521 gggcggagca ccgcgtcgtc acggccgcct acggcaccaa gcagtaccgt caccccctcg
    35581 tcggcgacct caccctcgac tgcgacacct gggccagtcc ggacggctcg ggacagcgcc
    35641 tcatggtcct gaccgccgag ccgggcagcc cctcccacga cgccctgcgc atcctcacct
    35701 cctggaccac gcggcagccc gctctcagcg gggacaacgg cgggccgccg tagccatctg
    35761 gcactcagca tcgagaaggc catcgaggac gcccggctga gggaggcacc cgtggccgtc
    35821 gccctgcacc gctacgtcga gaacatcatc gccgtcaacc gcacctggcc cgtggacctc
    35881 gcccgcatgc tggccgacga gagcgtgcgc gcacgccgcg atgcggccgt ccgcgaggtc
    35941 gacgccttcc tcgaacgggc caccgacgag gggcttctgc ggcgcggcct cccggaaggg
    36001 tgggcgagtg cgctccttcc ggacctcatg cacctggtgt cccgccagcg ccccgaactc
    36061 accccgggcc aggcggcgga catcgtcgtc gacacgctgc tgcacggcct cggcgcgtcc
    36121 tgacacggac gagggcgact cctgacacgc gacgagggcg actcctgagc gaggacctcg
    36181 gagaagccgt cgaccgcccc gctcggccgc ctgatgggcg cccaggccgg ggacgcaggc
    36241 ccgtccgccg ccgtagggct ggcctcttgt cgagtggtga ggccgggtca tggtgggcgt
    36301 catgccgcgc ctcctgaagg ggggaaggtt ctttccccgg cagaaacctg tctctcccgc
    36361 ccgcgcggcg gatgacggac ggtggatgcg tgcccggcag acagcggtcc cgaggggccc
    36421 gccgcccggc acggtcacga cacccgtcaa cccttcggag gagtgcgccc catggccagg
    36481 accaccgtca ccttcgacag cgccggcatc gacatcgccg cccacctcta cgtccccgac
    36541 accccggcgt cgggcccgcg cccggcgctg gtcgtcggcc accccggtac gggcgtgaag
    36601 gagcagacgt ccggcacgta cgcgcggctg atggccgaac gcggcttcgt caccctggcc
    36661 ttcgacgccg cccaccaggg cgagtccggt ggcctgccgc gcgggctgga ggaccccgcg
    36721 cagcgcgtgg aggacttcaa ggctgctgtg tccttcctga ccacccgtca ggaggtcgac
    36781 gcggagcgca tcggcctgct cggcatctgc gcttccggcg gctactcgct ggccgccacc
    36841 ggcggcgacc accgggtcag ggcggtggcc acggtgtgca ccgccgaccc ttcccggcag
    36901 ttccgcctcg gcgccgaggg cggccaggac cccgccgtct tccaggccct gctggacgcc
    36961 gccgcccggg cccgtaccgc cgccgcccgc ggcgaggatc ccggcgtgat gacgatgttc
    37021 ccggagacgg cggaggaggc gcgcgcgctc ggtggtgagc acggcgccga gggcttcgag
    37081 tactactgca cctcgcgggg cgcgcatgac aggtccgcca aggtcctcgc ctgggagagc
    37141 atcgacaaac tcgccttcta cgacgccttc ttcgcggtgc cgttgatcgg cccccgcccg
    37201 atgctccaga tcatcggcga gcgcgccgtc accgcctgga tggcggtcga ggcgcaccag
    37261 cgggcgaccg gtcccaagga gctgtaccgg atcccgggcg ccagccacgt cgacctgtac
    37321 gacaagaagc agtacatcga cctcgccgtc gagaagctca ccggcttctt caccgccaac
    37381 ctgggcacca ccgcggcctg accggcgcgc ggcgttgact tacgtcagcc cccgtccgcg
    37441 ccccgcgcgg cttcgccgac tgccgacccc ggggccgcac cgctcgaccg tcaagtgacc
    37501 gatgtgcccc accgacccac ggcggacagt gggttgcgca gattccggac caccgagggg
    37561 aacccctgtc atgcaccctg atcactcacc gctccgggcg cgctcggcac cccaccacgt
    37621 gccgccgctc ctcctcgaag tcgaccagat gctcgacgag ttcacgcgtc aggccgttca
    37681 ggcggagttc cggttcgacc cggacctgcc cgcggtgatc aacgtggagt tcctggcgga
    37741 acgcggcccc accgcggtct ggcggatcgg ccgcgagctc ctgcagcgcg ggctgacggc
    37801 gatgagcggc tcgtgcgacg tacggatgtg gccgaccctg cccggcgagc ggccctcgtc
    37861 ctggctgctc ctcgaatcgc aggaagtgga ggcgctgttc gagctgccca ccacggagct
    37921 ggcggagtgg ctggaagcca cctaccaggt cgcccccgcc gagacggaga tggacggcct
    37981 ggactgggac ggcttcctgc gggggctgct gggtgggccg gcggtaccgg gcgaatgagt
    38041 cagcgccgga acggaaggac gcagcggaag ctggaggcca gggacgggtc gccgtggccc
    38101 cggtagcggg acacctcggg gtaggcacac aggtcgcgtt ggagttgccg gccttcggcg
    38161 ttgacgagcg tggcgggcag ggtcctcggc gccttgccgt gctcgaccca ggcggtcagc
    38221 gcggccaggc cgtcggtctt gccgtcctgt ccgtcgaggc cgcagtggtc ggtgttcggg
    38281 gcgaggaagg gccggtagaa gtcgtcgacc ttccgggcac tgcccgtctc ccgcacgaca
    38341 cgccggcggt agtccacggt gccctgcggc gggatgtact ggtccgcctg gccctgccag
    38401 gtcaggagct tgccgccgga ctcacggaag gccgacaggt cgggatcgtc ggtgtccatg
    38461 atgtcgccgt actcggccac ggcctgccgg aacagttcgg tgaactcgcc gtaggtgagg
    38521 gtcgagacgt cgaaggacgg gtccttcttc acccagctcg ccgtccagtg ggcgggcacc
    38581 ggaaacggcg ctcccttgag gttgccgtcg gcgtcggccg cggtgcccgc gaggcccttc
    38641 aggtcggccc cgaccgggac gcccgcccac agcttcctgc cggaggcggt gcgcgggccg
    38701 tcccagatct tgtggacgac ggccgcgtcc gcggcggtga cggtcagctc cttgccctcg
    38761 cacagcacct tcgtgccgat cagccggcgc gggtcgaagt cgcagcggga agcgtcgttg
    38821 acgaggccgt cccgggcgcc gtccagcgtg tcgcaggcct tgacggcggc agtggtgaag
    38881 gcgtccagca cgcagccgga cacataggtc ttctcgttgt gcatgacgac ctgcggccac
    38941 agggtggcca gcacgtagcg gtcccagttg acggcgggcg cgtcggcgag gatgccgtcg
    39001 tagtcgtccg ggtagcgctg ggcctccatg tagccctggc gtccgccggt ggagcaaccg
    39061 gtgaagtagg agtacgcggc tgccttgccg tagaccgcgt cgacgacctg cttgccgacg
    39121 accgccgcct cgtgctggga acgggacgcg aagttctcca gcagggcggt gttgacctgc
    39181 ccctgctcgt tcagggccca gccgacgtcg aggacgtcgc cgaccccggc gtcggtggtg
    39241 gtcgccgcgt aaccgttctt caccgcggcg gcgaggccgg tgccgttgtc cccggccgag
    39301 aaggcggcac cgccgagcgc ctggaggcga ccgttccagc cggtgacggg cagccaggtc
    39361 cggatcctgg cgtggtctcc gtcgccgggg tgggtgacgg tgacggtcac ctcgcagtag
    39421 gcgggtacgc cggtgacggt gccgcccagg atgccgctgc cgtggacggt gccgccttcc
    39481 tggcggaccg cggtcacgga ctcgacgcgg gtgccggccg ggaccttcac cggcgtcgcc
    39541 acgcagccga ccggggtgga cgcggaggtc cggggttcgg cgtacgcggt cggcaggtac
    39601 acagccgcgg ccagcggcac gccggccgcg aggacagtga gaagtcgtct catgggtttc
    39661 ccattcgaga gaagaggtgt gcgtgcggcg atggcggcgc acacatgtgc acggcacaag
    39721 agcaggaggt gggaagtctg agcgagacgc tatcaccggt tagacaggtg acgaaaggag
    39781 gtgtcgatgg aattcccgga gggagcgcgc ggctggggac cgacatcgcc tggaaccacc
    39841 tggtggcacg gcgcctgtta cgctgtgatc gacctggttc atgtgatcga ggagtcgcag
    39901 acgtggtggg tgaagacgac atctccgggt gagatccgga tctgacggcc accggccggc
    39961 gcacaaggag cgctgccgcc gacgtggccc gtctcgcgta ccccttttcc ccatgtctgc
    40021 ccagggcaga ggtctgtgtt ctgccctccg tgccttcgag gtcatctcca tgtccgacgc
    40081 cgccgtcgtc tgctccagcc tctccttcgc ctggcccgac gacacccccg tcttccgcga
    40141 cctgtccttc accgtggcca ccggccgcac cggcctggtc gcccccaacg gctccggcaa
    40201 gagcaccctg ctcaagctga tcgccggtga actcaagccc gccaccggct cggtgaccgt
    40261 cagcggcact ctgggctacc tcccccagag cctcccgctg accggcgatc tcaccgtcgg
    40321 cgaggtgctc ggcgtcgccg aggtgatccg cgcactggac gccgtcgagt ccggcgacgt
    40381 cagcgaggag cacttcacca ccatcggcga cgactgggac atcgaggagc gcacccgcgc
    40441 ccagctcgac cgcctcggcc tcgccggcct cgccctggac cgcagcctga gcaccctcag
    40501 cggcggccag gtcgtcaccc tcggcctcgc cgcccagctg ctcaagcgcc ccgacgtcct
    40561 cctgctcgac gaaccgacca acaacctcga cgccgaggcc cgccacaagc tctacgacgc
    40621 actctcggac ttcaccggct gcctgctgct ggtcagccac gaccgcgccc tgctcgaccg
    40681 catggaccgc atcgccgaac tcggcagcgg tgaactgcgc ttctacggcg gcaacttctc
    40741 cgagtacgag gaggccgtcc gcgccgagcg ggaggtcgcc gagaagaacg tccgcaacgc
    40801 cgagcaggaa ctcaagcgcg agaagcggga gatgcagcag gcccgcgaac gcgccgagcg
    40861 ccgcatgagc aacgcctcca ggaatctcaa gaacgccggc ctgcccaaga tcttcgccgg
    40921 cacgatgaag cgcggcgccc aggaggcggc cggcaggtcc ggccagatgc acgcctcccg
    40981 cgtcagcgag gccaaggccc gcctcgacga ggccggacgc gcggtgcgcg acgaacagcg
    41041 cctcaccctg gagctgcccg acacccacgt gcccgcaggc cgcaacctct tcctcggcga
    41101 gggcatgcag gtccaccacg acggccgtgc cgtcttcgcc gacggcggca tcgacctgac
    41161 cgtccgcggc cccgagcgca tcgcgctcac cgggcccaac ggcgccggca agaccaccct
    41221 gctgaggctg atcaccggag acctcacccc cgacagcggg gagatcaggc gcaacgacgg
    41281 ccgcatcgcc tacctctccc agcgcctgga cctcctcgac gtggaccgca ccgtggcgga
    41341 gaacttcgcc gcgtccgccc ccgagcggcc cgaggcggag cggatgaacc tgctcgcccg
    41401 cttcctcttc cggggcgccc gcgcccacct gcccgtcggc gtcctctccg gcggcgaacg
    41461 gctgcgcgcc accctggcct gcgtgctgtg cgccgagccg gccccccacc tgctcctgct
    41521 cgacgaaccg accaacaacc tcgacctggt cagcgcgggc cagttggaga gcgcgctcaa
    41581 ctcctaccag ggcgctttcc tggtggtcag ccatgacgag cggttcctcg ccgagatcgg
    41641 cgtcaaccgc tggctgcggc tggccgacgg ggtgctgcag gagacaggag cccccgaggt
    41701 gtgacccccg gcgtgtgacg tggcccgcgt ccgaggctcc gcgcccggcg ggccgaccac
    41761 cgaacacgtt ggacggttcc ccatgcccca gcccgctctg ctcgcccacg acctcgtccg
    41821 caccctggac ggccgtcgcg tcctcgacgg catctccctc accgccgccc ccgcccgccg
    41881 catcggcctg atcggcgaga acggcgtcgg caagtccacc ctgctgcgag tgctcgccgg
    41941 cgtcgacgaa cccgacgcgg gcagcgtctc acgccccgcc gacctgggct tcctccacca
    42001 ggagatgccc tacgacgccg acgccaccgt cggcgcggtg ctggacgagg cgctgcgcga
    42061 ggcccgcgag gacctcgccg aactggaacg gctcggtgag gaactcgccc gtgtcccgca
    42121 ggacgacccc cgccaccggg aactcctcga cgcctatggc aggcggctgg agcaggccca
    42181 ggaccgggag tcctgggacg ccgaccggcg cgcggccctg gtgctggacg gcctgggtct
    42241 cggcacggtc ggccacgacc gcacgctggg ctcgctgtcc ggcgggcagc gcggccggct
    42301 ggccctggca gcgctgctcg tacgacgccc ctccgcgctg ctgctcgacg agccgaccaa
    42361 ccacctcgac gacggcgccg cagccttcct cgaggagcag gtccgcgccc tgcccggaac
    42421 ggtcgtggtc gccagccacg accgggcctt cctggacgcc gtctgcaccg acctcgtcga
    42481 cctcgacccg gcggtggacg gcccggtccg cttcggcggc aactacacgg cctacctggg
    42541 cgaaaagcgt gccgagcggg agcgctggga gcggcggtac gccgaggagc agcaggagct
    42601 ggcggagctg cggcaggcgg tgggcgtgac cgcgcaccgg gtcgcccccg accggggtcg
    42661 caccgacaac gagaagatgg gctacggcca ccgggcgggc cgggtgcaga accagatctc
    42721 gcgccgggtg cgcaacgccg cccggcggct ggaggagctg gagcgctcca gggtgcccga
    42781 gccgccgcgc ccgctgcgct tcacggccgg ggagctggcc gcacgggccg aggagggcgc
    42841 ggagccgctg gtggccctgc ggaacgttcg ggtgcccggc cggctggcgc tggacgcgct
    42901 ggagatctcg gcgaccgacc ggctgctggt caccggcggc aacggagcgg gcaagtcgac
    42961 gctgctcgcc gtactcgccg ggcggctggc ggccgagggc gaggtgcgca ggcggcgccg
    43021 gctgacggtg gggctgctca cccaggacac cgtgttcgac cggcccgaac gcacggttcg
    43081 cgacacctac gagctgtcgc tgggcccggc acgggccgag caggtgccgc tggcctcgct
    43141 cggactgctg cacgaggcgg acctggacaa acccgtcggg cggctgtccg tcgggcagcg
    43201 gcggcggctg gcgctggcgc tgctggtggc ccgcccgccc cagctgctgc tgctcgacga
    43261 gccgaccaac cacctctccc cgcggctgtg cgacgaactg gaggaggccc tgggcaccgg
    43321 tcccggcgcc atcgccgtgg ccagccacga ccgctggctg cggcggcggt ggcagggccg
    43381 ggagctccgt ctggagcagg gagtccggct ggacgcgggg aacggacgac gggagaatgc
    43441 gggcacggtc cggtcggggg cctgagccgg ggggcctcgg ggtgccgtcc tcggcgcggc
    43501 acccttcaga gcggtgacgg gtccatggcg gcttcttgca ctccccaccc gtcacctgtc
    43561 aagatggtta cgtgaacctt gaccacgtat tcgtatgcgg acacccggtc ctcgacttcg
    43621 cggcgaccct gcgtgcccgg cgctcgaccc ggttcgagat gttcgtgacg ccggaccggc
    43681 tcaacgcctg gtacgtggag tccggagtcg tggacacgat cacccccgcc gaggaatccg
    43741 acgtccggga ggcggtcgcg gtacgcgagg ccctctaccg cctcgtcacc aaccgccgcc
    43801 tgggtgagga gttcgaccgc gaggcactcg ccgtggtcaa cggcgcggcg cgcaagacgc
    43861 ccgtgacgcc gcagctcacc ctgaccggcc ggcacaacga aggcaccccg gcgcaggccc
    43921 tggcgaccgt cgcgcgacag gccgtcgaac tgctcagcgg cccggacgtc ccgctgctga
    43981 aggagtgcgg caacccggag tgcacgcggg tctacatcga ccgctcccgg ggcatgcggc
    44041 gccagtggtg cggtatggag tcctgcggca acaagatcaa ggccgccgcc taccgcgcca
    44101 ggaagaagac cgtgccggcg tcggcgtgaa gagtggactg actcgtcccg cccgcccgag
    44161 caggtgcagg acgagcccgt cgtcgtgaag cagaagcccg ccgcaaggcg cccgttcggc
    44221 tagccgcgcc acacgttgtc gaaggccgcg ctctccacgt ccctgcgcag ccgcagtgcc
    44281 tccaggcgcg tcacggcgtc gccgacggcg gccaggaccg tcgtgaccgc gtcgccggtg
    44341 ggcgtctcag gggtctcgtc cggggcgtcc cccactaccg cggcgtcgat cagggcggtg
    44401 aggacgggtt cgcccgacgc gctgcgttcc tcggctcggg tacgttccgg ggagtcggcg
    44461 aggacgctcc gtcccctcca cggctggagg ccatgccgcc gggggcgggt gaagagcccg
    44521 gaccgctgca ggtcgtcgac gtacgcggcg gcgagatccc ggccgcggcg ccatagccag
    44581 tcctcgaccg tctcgtgcga tccgtgcccg gcgagagtgg cgaccgcctc gtccaggagc
    44641 cggtcgcccg ttgcgacagg caggccgggc accacccggt cgccgttcag ggtcagcgcc
    44701 tcgatctcca gcaggtcgat cacctcggca cccgccagcg cgagggacag gttcccctgc
    44761 tccacgggcc ggtcggccgg cctgccgagg gcgacgaggg cgaggtcgcg tgcggtggtc
    44821 atgtgtccct ccaggtctcc agcaggacat cggcgacttc agtgtcacgc tgccacgagg
    44881 gcacgctcac aggaagtccg aggcggcggg gccgtatccc gacagcaccg cgctcatcga
    44941 ccagctccac acctgctggg cgtccggccg ggcaggtggc tgcggggctt gcggggtacc
    45001 ggctcgccgc tcgcgggagc gggcaggggc acggtcgtgg gcgcgacgat cgacgatgtc
    45061 agtcacgcct tcagggagtg atgtcgtgga cgcgggggcg ggacggcggc gtccggcctt
    45121 ccgggtcgac aggtgcgtca tggaggccat gtcctgccct cgctcttcgg taggcggtgc
    45181 gggtgtggcg gaaggaaggg gagcgggagc gggtcccgtg ccgggggaag tggcacggga
    45241 cccgccgtca ggtggtcagg ccgcggctgt ggcgttgagg acgacgggca cgttgtcgcg
    45301 cgtggccttg gagtaggggc agatctggtg ggcggcctgc gccagctcct ctgcggtggc
    45361 ctggtcgacg ccgcccagga ccgggctgag gaccgcggag agcgagaact cgccgtcgtc
    45421 cccgtgggtg agggtgatct cggcggtgat gctggtactg gtcagccgta tcttgcgggt
    45481 tgtggcggcc cggcgcaggg cgccgaggaa gcacgcggcc cagccggcgg ccaggagctg
    45541 ctcggggttg gtcgcggtgc cggcgccgcc cagctccttg gggagggcga ggcccgtctc
    45601 cagaagaccg tcggaggagc ggacgtgacc gccgttgcgg ccctctccgt cgacatcgac
    45661 gacggcggtg tagctgactg ccatggctgg gctccccatc tggttcgact cgatgctccg
    45721 ccacctcctg tgaacactgc tcgcgtcact ggttgaggtg gtgacgccat catggcagcc
    45781 ttgcgcgtca ccggtcaagc aggtgatgtg gacgtctgtg gggtgcagtc gtcgcgtcga
    45841 gcccctcccc ggggggtggc ccggcctgtg cacgccgcgg atcaccgaga ttcagtcatt
    45901 cgactgtcgt ccggggcccc cgccgcaacc atgctgggac agccgccggt gcgctggtgc
    45961 gtgcgccggt ggaattggtc gtcgtgctcg gaggagccat ccgtggaacg cactcccgtc
    46021 gtcttcatcc atggcgcgtg gctgcacgcg ctctcctggg agccgtgggt ggcacgcttc
    46081 gccggcaggg gcttcctggc cgtcgcgccc gggtggccgg gggaggccgc ggccgtcgcg
    46141 gacgtgcgcg cgtcaccgga accgctcagc cgtatcggtc tggacgcgct gaccgaccac
    46201 tacgccgagt tcgtgcggtc gttcgacacc gcaccggtga tcgtcggaca ctcggtaggc
    46261 gggctgatcg cacagcacct catcgcagcc gatgtcggcc gtgccgccgt cgccatcgcc
    46321 cccgcgcccg tcaacgacat cccgctgccc gcgtcccccg gccggctgct gcggcgcgac
    46381 cggtgcgacc ccgccgacga gttggtgccc ctgtcaccgg aacagttcca ccgcgccatc
    46441 gccaacacac tcgaagcgga ggagtccggc cggctctacg accgctacgt cgtaccggca
    46501 ccacgccgac tgctcgccga cctcggctgc gctgatgcgc cccgcagccc gcgcgccgcg
    46561 gcggacgtcg ggaacgcggg acgcggaccg ctcctgctga tctccggaca ggaggaccgg
    46621 ctcgtaccgg acgaggcgac acgcgccgtg tacaagcagt acggcgacac cacggccgtc
    46681 accgatctga agcagttcgc ggaccgcgcc cactccctgg tcatcgacag cggatggcgt
    46741 ttcgtcgccg actacgtgct gggctggctg gacgagcacg gcatccgagc ccaccagccg
    46801 gaggagtgac gcgccgcagt ccgggccgcg gtcaggcgtc cggactgcca ggcgtccgga
    46861 ctgtcaggcg tccgaaccgt cgggcatcct gcccagggcg tcgcgcagtg cggcgcggga
    46921 ggtgatgccc agcttgggga acacccggta caggtgtgag ctgaccgtac gcggcgacag
    46981 gtgcatccgc gcgccgatct ccttgttggt caggccgccg gcggcgaggt ccgctatccg
    47041 gcgctcctgc caggtcaggg acgccaggtg cgccgaagag gcgagcgggg atgctcccgc
    47101 ggcccgtagt tcggcccggg ctcgttcggc ccaggtgggg gcaccgaggc ggtcgaaggt
    47161 gtcggtggcg agggtgaggg tgtgtcgggc ggccttgcgg ccttgggtgt ggcgcaggcg
    47221 gatgccgtgg gcgaggcgga tgcgggcgag ttcgtaggga aaggcgtgcg cgccggggtg
    47281 ggtttcggct tgccggtagt ggtggtcggc ttcggcgggg tcggcggctg tcatggcgag
    47341 ggcgccgtgg
//
