LOCUS       NZ_BNBM01000030        40618 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces lanatus strain JCM 4588 sequence30, whole genome
            shotgun sequence.
ACCESSION   NZ_BNBM01000030
VERSION     NZ_BNBM01000030.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces lanatus
  ORGANISM  Streptomyces lanatus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 85825)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 61X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014655715.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 05:46:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,254
            CDSs (total)                      :: 9,172
            Genes (coding)                    :: 8,973
            CDSs (with protein)               :: 8,973
            Genes (RNA)                       :: 82
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 199
            CDSs (without protein)            :: 199
            Pseudo Genes (ambiguous residues) :: 0 of 199
            Pseudo Genes (frameshifted)       :: 83 of 199
            Pseudo Genes (incomplete)         :: 153 of 199
            Pseudo Genes (internal stop)      :: 16 of 199
            Pseudo Genes (multiple problems)  :: 50 of 199
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:57:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 40618
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BNBM01000030.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..40618
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T2PKS"
                     /region_number="1"
                     /rules="(t2ks and t2clf)"
                     /tool="antismash"
     gene            <1..1007
                     /locus_tag="IE325_RS44260"
     cand_cluster    1..40618
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(t2ks and t2clf)"
                     /kind="single"
                     /product="T2PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..40618
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[3096:5618](+)"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="8|9 (Score: 704.6; E-value:
                     7.1e-215)"
                     /t2pks_molecular_weights="acetyl-CoA_8 (Da): 351.372"
                     /t2pks_molecular_weights="acetyl-CoA_9 (Da): 393.408"
                     /t2pks_product_classes="angucycline"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
                     /tool="antismash"
     proto_core      3097..5618
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="8|9 (Score: 704.6; E-value:
                     7.1e-215)"
                     /t2pks_molecular_weights="acetyl-CoA_8 (Da): 351.372"
                     /t2pks_molecular_weights="acetyl-CoA_9 (Da): 393.408"
                     /t2pks_product_classes="angucycline"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
     CDS             <5..1007
                     /codon_start=3
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003948354.1"
                     /locus_tag="IE325_RS44260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="biotin/lipoyl-containing protein"
                     /protein_id="WP_190075881.1"
                     /transl_table=11
                     /translation="VAELYSSSKAILKEAGYVGAGTVEFLVGLDGTISFLEVNTRLQVE
                     HPVTEEIAGIDLVREMFRIADGEELGYGDPVLRGHSFEFRINGEDPGRGFLPAPGTVTT
                     FAPPSGPGVRLDAGVESGSVIGPAWDSLLAKLIVTGATREQALQRAARALAEFQVEGMA
                     TAIPFHRAVVTDPAFTGEPFTVHTRWIETEFANTIKPFAAPADNDADEETGRESVVVEV
                     GGKRLEVSLPSSLGMTLARTGLAAGAKPKRRAAKKSGPAASGDTLASPMQGTIVKVAVE
                     EGQEVEEGDLIVVLEAMKMEQPLNAHKSGTIKGLSAEIGASLTSGAGICEIMG"
     gene            1266..2738
                     /locus_tag="IE325_RS44265"
                     /old_locus_tag="GCM10018780_89910"
     CDS             1266..2738
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 611.1; E-value: 3.5e-186)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432353.1"
                     /locus_tag="IE325_RS44265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_89910"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_190075882.1"
                     /transl_table=11
                     /translation="MDAAVIVVGAGPAGMMLAGELRLGGVDVIVLERLTERTGESRGLG
                     FTARTMEVFDQRGMLPRFGEIETSNQGHFGGLPVDFGVLEGAWQAAKTVPQSVTEQHLE
                     EWASSLGADIRRGHEFLSLKDEGDAVEVEVRGPEGVHRLRAAYLVGCDGGRSAVRKAAG
                     FDFPGTAATMEMFLADLKGVDIQPRMIGETLPGGMVMAGPLPGDVTRIIVCERGTPPQR
                     REVPPSFEEVADAWKRLTGDDISHAEPVWVSSFGDATRQVTEYRRGRVILAGDSAHIHL
                     PAGGQGMNTSIQDAVNLGWKLAAEVRGWAPAGLLDTYHSERHAVGKRLLMNTQAQGLLF
                     LSGPEVQPLRDVLTELIGYRNVAQHLAAMVSGLEITYDVGGGSHPLLGRRMPQLELAAS
                     VRATSSTELLHSARGLLLDLEDNPRLRARAAAWADRVDTVTAEPGAVTEAGGLRGTSAV
                     LVRPDGHVAWAAPGSHHDLGMALERWFGAPRT"
     gene            2786..3130
                     /locus_tag="IE325_RS44270"
                     /old_locus_tag="GCM10018780_89920"
     CDS             2786..3130
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1225: Polyketide synthesis cyclase"
                     /gene_functions="biosynthetic-additional (t2pks) CYC
                     C4-C17/C2-C19 (Score: 201.5; E-value: 2.8e-62)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037157.1"
                     /locus_tag="IE325_RS44270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_89920"
                     /product="TcmI family type II polyketide cyclase"
                     /protein_id="WP_190075883.1"
                     /transl_table=11
                     /translation="MHSTLIVARMDIESSAEVGRLFAEFDRTEMPHRMGTRRRQLFAYK
                     GLYFHLQDFDADNGGELIEDAKTDPRFVQISDDLKPFIEAYDPATWRSPADAMATRFYD
                     WTADTTGGHR"
     gene            3097..4398
                     /locus_tag="IE325_RS44275"
                     /old_locus_tag="GCM10018780_89930"
     CDS             3097..4398
                     /EC_number="2.3.1.-"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (15-406). E-value:
                     1.9e-54. Score: 177.1. Matches aSDomain:
                     nrpspksdomains_IE325_RS44275_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_functions="biosynthetic-additional (t2pks) KS (Score:
                     795.1; E-value: 3e-242)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511392.1"
                     /locus_tag="IE325_RS44275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_89930"
                     /product="beta-ketoacyl-[acyl-carrier-protein] synthase
                     family protein"
                     /protein_id="WP_308437723.1"
                     /sec_met_domain="t2ks (E-value: 3.9e-253, bitscore: 832.3,
                     seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.2e-57, bitscore:
                     187.8, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDGRHDGRPPLVARRVVITGVGVLAPGGIGAKNFWSLLSEGRTAT
                     RGITFFDPSAFRSRVAAEVDFDPYLQGLSPQEIRRMDRAAQFAVVTAREALADSGLDLG
                     GFDPHRTGVTIGSAVGATTGLDDEYRVVSDDGRLDLVDHTYAPQHLYNYFVPSSFSAEV
                     AWAVGAEGPAAVVSTGCTSGIDSVGHAVDLIREGTADIMITGATDAPISPITMACFDAI
                     KATTPRNDDPEHASRPFDGTRNGFVLGEGSAAFVLEELDSARRRGAHIYAEIAGYASRC
                     NAFHMTGLRPDGREMAEAITVALGEARMNPEAVDYINAHGSGTKQNDRHETAAFKLSLG
                     DHAYRRPVSSIKSMVGHSLGAIGSIEIAASVLAMENHVVPPTANLHTPDPECDLDYVPL
                     TAREHRTDTVLTVGSGFGGFQSAMVLARPDRSVS"
     aSDomain        3142..4314
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS44275_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.90E-54"
                     /label="IE325_RS44275_PKS_KS.1"
                     /locus_tag="IE325_RS44275"
                     /protein_end="406"
                     /protein_start="15"
                     /score="177.1"
                     /tool="antismash"
                     /translation="VVITGVGVLAPGGIGAKNFWSLLSEGRTATRGITFFDPSAFRSRV
                     AAEVDFDPYLQGLSPQEIRRMDRAAQFAVVTAREALADSGLDLGGFDPHRTGVTIGSAV
                     GATTGLDDEYRVVSDDGRLDLVDHTYAPQHLYNYFVPSSFSAEVAWAVGAEGPAAVVST
                     GCTSGIDSVGHAVDLIREGTADIMITGATDAPISPITMACFDAIKATTPRNDDPEHASR
                     PFDGTRNGFVLGEGSAAFVLEELDSARRRGAHIYAEIAGYASRCNAFHMTGLRPDGREM
                     AEAITVALGEARMNPEAVDYINAHGSGTKQNDRHETAAFKLSLGDHAYRRPVSSIKSMV
                     GHSLGAIGSIEIAASVLAMENHVVPPTANLHTPDPECDLDYVPLTAREHRT"
     gene            4395..5618
                     /locus_tag="IE325_RS44280"
                     /old_locus_tag="GCM10018780_89940"
     CDS             4395..5618
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (68-405). E-value:
                     9.8e-31. Score: 99.0. Matches aSDomain:
                     nrpspksdomains_IE325_RS44280_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093: Beta-ketoacyl synthase"
                     /gene_functions="biosynthetic-additional (t2pks) CLF 8|9
                     (Score: 704.6; E-value: 7.1e-215)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018488940.1"
                     /locus_tag="IE325_RS44280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_89940"
                     /product="ketosynthase chain-length factor"
                     /protein_id="WP_190075885.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 4.4e-46, bitscore:
                     150.0, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="t2clf (E-value: 3.3e-212, bitscore: 696.9,
                     seeds: 26, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTSTRTVITGIGVATPSGLGIDDFWAATRVGKNAIGRVTHFDPT
                     SYPSRLAGEIRHFAAEELLPSRLIPQTDRMTRLALVAADWAFADAGIKPGDIPEFDMGV
                     VTASTSGGFEFGQNELKKLWSQGSQYVSAYQSFAWFYAVNSGQISIRNGMRGPSGVVVS
                     DHAGGLDAIAQARRQIRKGSKVIFSGGFDASICTWGWVAQIAGGRMSTSDDPDRAFLPF
                     DADADGYVPGEGGALLVLEDELTARERGARTVYGEIAGYGSTFDPKPGSGREPGLRRAI
                     EVALADAGVETGEVDVVFADAAGTPRLDREEADAINAVFGRHGVPVTAPKTMTGRLYSG
                     AAPVDVVSAVLAIREGLIPPTVNVEPSPEYGIDLVTAQPRSASVRTALVLARGHGGYNS
                     AVVVRAVD"
     aSDomain        4599..5609
                     /ASF="found active site histidines: False"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS44280_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="9.80E-31"
                     /label="IE325_RS44280_PKS_KS.1"
                     /locus_tag="IE325_RS44280"
                     /protein_end="405"
                     /protein_start="68"
                     /score="99.0"
                     /tool="antismash"
                     /translation="IPQTDRMTRLALVAADWAFADAGIKPGDIPEFDMGVVTASTSGGF
                     EFGQNELKKLWSQGSQYVSAYQSFAWFYAVNSGQISIRNGMRGPSGVVVSDHAGGLDAI
                     AQARRQIRKGSKVIFSGGFDASICTWGWVAQIAGGRMSTSDDPDRAFLPFDADADGYVP
                     GEGGALLVLEDELTARERGARTVYGEIAGYGSTFDPKPGSGREPGLRRAIEVALADAGV
                     ETGEVDVVFADAAGTPRLDREEADAINAVFGRHGVPVTAPKTMTGRLYSGAAPVDVVSA
                     VLAIREGLIPPTVNVEPSPEYGIDLVTAQPRSASVRTALVLARGHGGYNSAVVVRA"
     CDS_motif       5058..5096
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS44280_0001"
                     /evalue="2.20E-05"
                     /label="PKSI-KS_m4"
                     /locus_tag="IE325_RS44280"
                     /protein_end="234"
                     /protein_start="221"
                     /score="17.1"
                     /tool="antismash"
                     /translation="FDADADGYVPGEG"
     gene            5663..5938
                     /locus_tag="IE325_RS44285"
                     /old_locus_tag="GCM10018780_89950"
     CDS             5663..5938
                     /GO_function="GO:0000036 - acyl carrier activity [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: ACP (12-82). E-value: 2.6e-19. Score:
                     61.3. Matches aSDomain: nrpspksdomains_IE325_RS44285_ACP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129: acyl carrier protein"
                     /gene_functions="biosynthetic-additional (t2pks) ACP
                     (Score: 133.2; E-value: 5.7e-42)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037163.1"
                     /locus_tag="IE325_RS44285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_89950"
                     /product="acyl carrier protein"
                     /protein_id="WP_190075886.1"
                     /sec_met_domain="PP-binding (E-value: 1e-12, bitscore:
                     41.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSERKFTFDALKRILREGAGADEGVDLDGDILDADFEELGYESLA
                     LLETGGRIEREYGISLDDDIFTDHRTPRALVAAVNELLKDNTVSAA"
     aSDomain        5699..5908
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS44285_ACP.1"
                     /evalue="2.60E-19"
                     /label="IE325_RS44285_ACP.1"
                     /locus_tag="IE325_RS44285"
                     /protein_end="82"
                     /protein_start="12"
                     /score="61.3"
                     /tool="antismash"
                     /translation="RILREGAGADEGVDLDGDILDADFEELGYESLALLETGGRIEREY
                     GISLDDDIFTDHRTPRALVAAVNEL"
     gene            5975..6760
                     /gene="fabG"
                     /locus_tag="IE325_RS44290"
                     /old_locus_tag="GCM10018780_89960"
     CDS             5975..6760
                     /EC_number="1.1.1.100"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (7-163). E-value: 4.2e-11. Score:
                     35.0. Matches aSDomain:
                     nrpspksdomains_IE325_RS44290_PKS_KR.1"
                     /codon_start=1
                     /gene="fabG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_functions="biosynthetic-additional (t2pks) KR C9
                     (Score: 488.4; E-value: 1.1e-149)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018103042.1"
                     /locus_tag="IE325_RS44290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_89960"
                     /product="3-oxoacyl-ACP reductase FabG"
                     /protein_id="WP_190075887.1"
                     /sec_met_domain="adh_short (E-value: 9e-38, bitscore:
                     122.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQQDKPVALVTGATSGIGLAVARLLASGGHRVFIGARNAENLAA
                     TVKQLQDDGLEADGTTLDVRSVEDCRAFVRAAVERFGTVDVLVNNAGRSGGGVTADIAD
                     ELWEDVIDTNLNSVFRMTREVLETGGMRHKDRGRIINIASTAGKQGVVLGAPYSASKHG
                     VVGFTKALGNELAPTGITVNAVCPGYVETPMAQRVRQGYAAAYDTSEDAILEKFQAKIP
                     LGRYSTPEEVAGLVGYLTSDSAASITSQALNVCGGLGNF"
     aSDomain        5996..6463
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS44290_PKS_KR.1"
                     /evalue="4.20E-11"
                     /label="IE325_RS44290_PKS_KR.1"
                     /locus_tag="IE325_RS44290"
                     /protein_end="163"
                     /protein_start="7"
                     /score="35.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VALVTGATSGIGLAVARLLASGGHRVFIGARNAENLAATVKQLQD
                     DGLEADGTTLDVRSVEDCRAFVRAAVERFGTVDVLVNNAGRSGGGVTADIADELWEDVI
                     DTNLNSVFRMTREVLETGGMRHKDRGRIINIASTAGKQGVVLGAPYSASKHG"
     CDS_motif       6002..6070
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS44290_0001"
                     /evalue="4.60E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE325_RS44290"
                     /protein_end="32"
                     /protein_start="9"
                     /score="19.3"
                     /tool="antismash"
                     /translation="LVTGATSGIGLAVARLLASGGHR"
     gene            6794..7738
                     /locus_tag="IE325_RS44295"
                     /old_locus_tag="GCM10018780_89970"
     CDS             6794..7738
                     /NRPS_PKS="Domain: Polyketide_cyc2 (7-149). E-value:
                     3.2e-15. Score: 48.7. Matches aSDomain:
                     nrpspksdomains_IE325_RS44295_Polyketide_cyc2.1"
                     /NRPS_PKS="Domain: Polyketide_cyc2 (158-295). E-value:
                     2.8e-11. Score: 35.9. Matches aSDomain:
                     nrpspksdomains_IE325_RS44295_Polyketide_cyc2.2"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128: cyclase/dehydrase"
                     /gene_functions="biosynthetic-additional (t2pks) CYC C7-C12
                     (Score: 506.8; E-value: 4e-155)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007269009.1"
                     /locus_tag="IE325_RS44295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_89970"
                     /product="aromatase/cyclase"
                     /protein_id="WP_190075888.1"
                     /transl_table=11
                     /translation="MPKPGPREVEHEITVSAPATAVYRLIAEVENWPRIFPPTIHVDHV
                     EKGDRTERIRIWATANGEAKNWTSRRTLDPEELRIGFRQEVSAPPVAEMGGTWVIEPVS
                     DTVSRIRLLHDYRAVDDDPAGLAWIDEAVDRNSRSELAALKENVERAVASEELTFSFED
                     TVQIAGSAKDVYDFVNDAHLWAERLPHVASVRLDEDTPGLQTLEMDTRAKDGSTHTTKS
                     YRVTFPHRKIAYKQVTLPALMTLHTGYWTFAENDAGVAASSQHTVTINTENITRVLGAD
                     ATVADAREYVQAALSTNSRATLGHARDYAEARA"
     aSDomain        6815..7240
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS44295_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="3.20E-15"
                     /label="IE325_RS44295_Polyketide_cyc2.1"
                     /locus_tag="IE325_RS44295"
                     /protein_end="149"
                     /protein_start="7"
                     /score="48.7"
                     /tool="antismash"
                     /translation="EVEHEITVSAPATAVYRLIAEVENWPRIFPPTIHVDHVEKGDRTE
                     RIRIWATANGEAKNWTSRRTLDPEELRIGFRQEVSAPPVAEMGGTWVIEPVSDTVSRIR
                     LLHDYRAVDDDPAGLAWIDEAVDRNSRSELAALKENVE"
     aSModule        6815..7678
                     /domains="nrpspksdomains_IE325_RS44295_Polyketide_cyc2.1"
                     /domains="nrpspksdomains_IE325_RS44295_Polyketide_cyc2.2"
                     /incomplete
                     /locus_tags="IE325_RS44295"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        7268..7678
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS44295_Polyketide_cyc2.2"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="2.80E-11"
                     /label="IE325_RS44295_Polyketide_cyc2.2"
                     /locus_tag="IE325_RS44295"
                     /protein_end="295"
                     /protein_start="158"
                     /score="35.9"
                     /tool="antismash"
                     /translation="FSFEDTVQIAGSAKDVYDFVNDAHLWAERLPHVASVRLDEDTPGL
                     QTLEMDTRAKDGSTHTTKSYRVTFPHRKIAYKQVTLPALMTLHTGYWTFAENDAGVAAS
                     SQHTVTINTENITRVLGADATVADAREYVQAAL"
     gene            7741..9969
                     /locus_tag="IE325_RS44300"
                     /old_locus_tag="GCM10018780_89980"
     CDS             7741..9969
                     /NRPS_PKS="Domain: PKS_KR (496-669). E-value: 5.9e-09.
                     Score: 28.0. Matches aSDomain:
                     nrpspksdomains_IE325_RS44300_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_functions="biosynthetic-additional (t2pks) KR C15
                     (Score: 500.2; E-value: 2.6e-153)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511397.1"
                     /locus_tag="IE325_RS44300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_89980"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_190075889.1"
                     /transl_table=11
                     /translation="MAGDRIATDVIVVGAGPVGLMLAGELRGAGADVVVLEKLTAPTTE
                     SRASTLHARTMEILESRGLLAPLGDIPNDRRGHFGGIPLDLTLPGRHPGQWKVPQTRIE
                     ELLGQWARGLGADIRRGHELTGLTMTADHVEAAVRLPDGTTTSLRAGYVVGCDGEHSAV
                     RRLGGFDFPGSDAERELLRADVAGIDIPDRRFQRLAGGLAIAARRPDGVTRVMVHEFGA
                     RPRGGQPGFQDITDSWKRVTGEDIGHGTPLWVNSFGDASRQAARYRDHRLLLAGDAAHQ
                     KMPIGGQALNLGLQDAVNLGWKLAAEVRGRAPEGLLDSYHDERHAVGRRTLNNIRAQAL
                     LLLGSAEVEAVRRIYAELAAGSENVRTHLAGMISGLDIRYDVGGGRHPLQGRRLAQRDL
                     FRAGRGLLLLTPGAEELRTVAAPWGDLVDTAAAPPGDVPPDLGAVLVRPDGHVVWTDAE
                     DTAITTALTRWFGTPKRQSDRTTTRNRSTDMSSRLTGRTALVTGASRGMGRATALRLAQ
                     EGALVAVHYSTSEEAAEEVVELIEKDGGRAFAVRAELGVAGDVHELFLGLENGLRERTG
                     TTDLDILVNNAGVMGGVKPEDTTPEQFDRLFAVNAKAPFFLIQRALKNMRDGGRIINIT
                     SGLTRFANPDEIAYAMTKGAVDQLALHFAKLLGPRNITVNSVAPGITRNGNPVFGIPEA
                     VEQMAQLSAFNRVGEPEDVADVVAFLATDEARWITGSFVDATGGTLLG"
     CDS_motif       7774..7848
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS44300_0001"
                     /evalue="1.40E+01"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE325_RS44300"
                     /protein_end="36"
                     /protein_start="11"
                     /score="-1.5"
                     /tool="antismash"
                     /translation="VVGAGPVGLMLAGELRGAGADVVVL"
     aSDomain        9229..9747
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS44300_PKS_KR.1"
                     /evalue="5.90E-09"
                     /label="IE325_RS44300_PKS_KR.1"
                     /locus_tag="IE325_RS44300"
                     /protein_end="669"
                     /protein_start="496"
                     /score="28.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALVTGASRGMGRATALRLAQEGALVAVHYSTSEEAAEEVVELIE
                     KDGGRAFAVRAELGVAGDVHELFLGLENGLRERTGTTDLDILVNNAGVMGGVKPEDTTP
                     EQFDRLFAVNAKAPFFLIQRALKNMRDGGRIINITSGLTRFANPDEIAYAMTKGAVDQL
                     ALHFAKLLGP"
     CDS_motif       9235..9300
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS44300_0002"
                     /evalue="4.40E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE325_RS44300"
                     /protein_end="520"
                     /protein_start="498"
                     /score="12.9"
                     /tool="antismash"
                     /translation="LVTGASRGMGRATALRLAQEGA"
     gene            10034..11431
                     /locus_tag="IE325_RS44305"
                     /old_locus_tag="GCM10018780_89990"
     CDS             10034..11431
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018488945.1"
                     /locus_tag="IE325_RS44305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_89990"
                     /product="MFS transporter"
                     /protein_id="WP_190075890.1"
                     /transl_table=11
                     /translation="MTSSTPSPTLTAGERFSPALWALLFVLAGNMLIDALEVSVALVAL
                     PAVSDDLALSVPQAQWVVSGFAVGFGGLLLFGSRLVTLLGRRRVYLAALLLFAVASLAG
                     AAAASGPLLIGTRLVKGFCAALTAPTGLAIILAVFPEGPVRARAVSVYSFFGAAGFSAG
                     LLLSGLLTETSWRWAFAFPAPVVLLLFVVGIRRIPRDEPAWDTEGRYGVPSALGLIGAT
                     LLLVYAIVSVPATGWTHPRTLGAFVLAALCAAVHVRAELTAAKPLLSLDLLRHAALVRS
                     ALGAAALNGSYLGLLLLSTLHLQQRAGWSPLQTGLAFLPASVPLALTALHSGRLAARFG
                     PARLIAAGAAAAPAGYLLYPRDAPTQVDYVIDVLPTMLLVGTAFVLAFAAFHLQATSSV
                     PAPRQAEASGLYQTAVQLGAALMLALTSALYGAGYGAALTLITAVGALGFAVAVSGLLP
                     GRRGVGR"
     gene            11428..12228
                     /locus_tag="IE325_RS44310"
                     /old_locus_tag="GCM10018780_90000"
     CDS             11428..12228
                     /NRPS_PKS="Domain: ACPS (128-192). E-value: 8.5e-08. Score:
                     24.0. Matches aSDomain:
                     nrpspksdomains_IE325_RS44310_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511399.1"
                     /locus_tag="IE325_RS44310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90000"
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="WP_190075891.1"
                     /transl_table=11
                     /translation="MSTAEPRPPQTQFTLGPDRLDLYLVRTPQGREAALLDRSELDDAE
                     RRRAGSFRHPAHALLYTTAHIALRRLLGRQLGVAPRDLRFLREPCPGCGAPHGRPAVAM
                     AGPPLHFSLSHSGGLVLIGVAAVAVGVDVQRLPREETVEVASAALHAGERAELGRRVRG
                     ADRTGHFGRLWTRKEAYLKAIGTGLHRSPARDYLGADSAVHPPGWTVLDVACPPTHSAA
                     AVVRGRRPRFVDVHRLDGRWLCTPDTPDALAIATTISTHGEVTT"
     aSDomain        11812..12003
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS44310_ACPS.1"
                     /evalue="8.50E-08"
                     /label="IE325_RS44310_ACPS.1"
                     /locus_tag="IE325_RS44310"
                     /protein_end="192"
                     /protein_start="128"
                     /score="24.0"
                     /tool="antismash"
                     /translation="VGVDVQRLPREETVEVASAALHAGERAELGRRVRGADRTGHFGRL
                     WTRKEAYLKAIGTGLHRSP"
     gene            12249..13790
                     /locus_tag="IE325_RS44315"
                     /old_locus_tag="GCM10018780_90010"
     CDS             12249..13790
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511400.1"
                     /locus_tag="IE325_RS44315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90010"
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_229912531.1"
                     /transl_table=11
                     /translation="MHRTEELTAIKESARGGPDPAATERQHAKGKLTAHERIELLLDKG
                     SFTEVEPLRRHRASGFGLEHRKPYSDGVVTGWGTVHGRTVFVYAHDFRIFGGALGEAHA
                     QKIHKVLDLAEAAGAPVVSLNDGAGARIQEGVTALAGYGGIFQRNTRSSGVIPQISVML
                     GPCAGGAAYSPALTDFVFMVRETSQMFITGPDVVRTVTGEEITQNGLGGADVHAAVSGV
                     AHFAYDDEEHCLEDVRYLLSLLPANNRELSPVVPCADPADRPGDVLLDLVPAGSGQAYD
                     IRKVIEEIVDDGEFFEVHPAWATNLVCALTRLDGHVVGVVANQPASMAGVLDIEASEKG
                     ARFVQFCDAFNIPLVTLVDVPGFLPGVDQEHNGIIRRGAKLLYAYCNATVPRISLVLRK
                     AYGGAYIVMDSRSIGADLTLAWPTNEIAVMGAEGAANVVFRREINAADDPEAVRQERIA
                     EYKAELMHPYYAAERGLIDDVIDPRETRSVLIRSLAMLRAKHADLPSRKHGNPPQ"
     misc_feature    12267..12280
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.06"
                     /tool="antismash"
     gene            13820..14722
                     /locus_tag="IE325_RS44320"
                     /old_locus_tag="GCM10018780_90020"
     CDS             13820..14722
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020135438.1"
                     /locus_tag="IE325_RS44320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90020"
                     /product="hypothetical protein"
                     /protein_id="WP_190075893.1"
                     /transl_table=11
                     /translation="MTPSLGPAARQCQKALNTLHSTVYFSPDLGGELAGRGVDDPMACY
                     LAGRAAALGRVGPGVVTAVFHNFRYDMIAGHLPALWDRVAPDQALAARLRAADATLRRA
                     LGAEALTARPMRDAARLALRAVEGCGRPGRPLYAAHADQPVPEAPHLALWHVATLLREH
                     RGDSHVGALSAAGLDGIEALVSHCASGEGMSREAVMGPRGWTKEDWDAAEERLRERGLM
                     AADGTLTPRGVRLRQDLEEETDRRDLDPYRHLGEAGVAELTDLAEEFVRNVVASGLFPP
                     DVEAFFLPPNRGPHTTPHT"
     gene            14857..15657
                     /locus_tag="IE325_RS44325"
                     /old_locus_tag="GCM10018780_90030"
     CDS             14857..15657
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF017026.5"
                     /locus_tag="IE325_RS44325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90030"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_190075894.1"
                     /transl_table=11
                     /translation="MADGAPEHSYSTGSLTRGTFSQLDQLRLFESKYDPVTRAVIESLD
                     VRPTWRCLELGAGAGSMSYWLAGQVPEGGVLAVDIDDSRLDADQAPQLTVRQADITATE
                     FEEGGYDLVLARAVLEHLKDPDELLTRAARWLAPGGWLVVEDFYYLPAEHAATAVGRTL
                     VAGYVRRMREQGADLGWARHLPASLARAGLESVGLRLTPAGPGQTPADDELIGLRLRQE
                     GHALVDAGVVTEDELAEFMGLLGRPEGRDMTTLMVSAWARRPAE"
     gene            15705..16625
                     /locus_tag="IE325_RS44330"
                     /old_locus_tag="GCM10018780_90040"
     CDS             15705..16625
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511402.1"
                     /locus_tag="IE325_RS44330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90040"
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_190075895.1"
                     /transl_table=11
                     /translation="MPEQPVQPEQPVQPEPSVQPEQPVVLITAATGNVGPHAAAHLLQA
                     GARVRALVLPDDPNIGRLPEGVEIHRGDLGDPDTLDAALDGVDGVFLMWPFFSLPVDSA
                     PTVLRKIEATARRVAFVSSVGVHIGLEPVDNNCHAYIEKLLEGTTLEWTFLRTTGFHCN
                     SAMTFADQVRTGDIVRFPYGAATRTSVHEGDLAAVGAKALTAEGHARKAYLVSGPQALS
                     QAAQLQVIAEVTGRELTWEDIEHDAARKAMVDAGWPPSYADGALDYFETLTRTPEVGSN
                     VVEEVTGRPARTFRDWVVEHTHLFH"
     gene            16657..17286
                     /locus_tag="IE325_RS44335"
                     /old_locus_tag="GCM10018780_90050"
     CDS             16657..17286
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE325_RS44335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10018780_90050"
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="WP_190075896.1"
                     /transl_table=11
                     /translation="MTRAPEPGFTTFDTLTTQSPDAARELAEALITEAATRLRHSPGFL
                     SSRVHVGDDRRTVIHRGLWRDAADHHAAADRLKELADRPGVQTAKTFAGTPAPGLHGPR
                     TGVLPGRVAVATRHLRDPESYPALMDLLNRSGDWKRHHRGFITATPHISPDQLTFVNYA
                     TWEDEDSYRAWMADPRISEGQEEIARLEAAPAEYVLCAVVADIRAA"
     gene            17407..18039
                     /locus_tag="IE325_RS44340"
                     /old_locus_tag="GCM10018780_90060"
     CDS             17407..18039
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018852147.1"
                     /locus_tag="IE325_RS44340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90060"
                     /product="DsbA family protein"
                     /protein_id="WP_190075897.1"
                     /transl_table=11
                     /translation="MTAVGSKPLRVEIALDLTCVHSYLGFNRFQRVAARHRAAGGGLDV
                     VFLPFQVSPEAPPEGRPLSEVHLAFFGSAEQAARATAGMAAVGAQDGLELNFERAVHVN
                     TFEAHRLLATAAHQGLGEPMAERLFRAYLTEGLNIGDRAVLDRLAAETGVRPTPDGAEE
                     LRAELTRVRALGISSVPQFRFTDTILLAGAQPEEALQRAFEAAAAGN"
     gene            18081..19016
                     /locus_tag="IE325_RS44345"
                     /old_locus_tag="GCM10018780_90070"
     CDS             18081..19016
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE325_RS44345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10018780_90070"
                     /product="hypothetical protein"
                     /protein_id="WP_190075898.1"
                     /transl_table=11
                     /translation="MRSGRTRRTLATAGVLLALSLTTGLSGAAVAEPLATARPAAVEEA
                     APQTLELKSSTDGLTAPTTAHPGPTTFRVSTTDPASGWISLVRPKPGVTFESFRASILK
                     MINAVGPDIVEGSAEMRQKAELLGGTVIHPNLPASFTRTLTPGTYWFFDYRNIRAENPR
                     HSVLTVGGTTGTGTAPAPAATLTGRMTDGQPRWNLDGTVRAGRPILFRNAMPDGQYIEA
                     IFFRLAADVTEQDVRDYVADFGDTGQFPDYPGPLDLEQGTGGLPMDSGQSSLLELTLQP
                     GRYVVVDFFSDAKDGSSLIKRGHWKIFEVK"
     gene            19046..19261
                     /locus_tag="IE325_RS44350"
                     /old_locus_tag="GCM10018780_90080"
     CDS             19046..19261
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_function="GO:0004658 - propionyl-CoA carboxylase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018850635.1"
                     /locus_tag="IE325_RS44350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90080"
                     /product="acyl-CoA carboxylase epsilon subunit"
                     /protein_id="WP_190075899.1"
                     /transl_table=11
                     /translation="MNLRIDYGTPDADELAALTAVLLALSEAPAHDTDTDGRPHIARWR
                     RPERMSGHRTPRSWRSATVRTSGWAA"
     gene            19249..20163
                     /locus_tag="IE325_RS44355"
                     /old_locus_tag="GCM10018780_90090"
     CDS             19249..20163
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (38-138). E-value:
                     4.7e-09. Score: 28.1. Matches aSDomain:
                     nrpspksdomains_IE325_RS44355_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268996.1"
                     /locus_tag="IE325_RS44355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90090"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_190075900.1"
                     /sec_met_domain="PF00561 (E-value: 4.2e-08, bitscore: 25.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6.5e-14, bitscore:
                     45.6, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGGVTERRAPEVRDITLDADGVEVSGLVAVPPSGPSRAVVVAVHG
                     GGMRAGYFDSRSRPGLSLLTLGAELGCTVLALDRPGYGLSAARLPEGQTVEEQAAGLHA
                     ALADFATRHDTGAGFFVVAHSYGGKIALATAAREGGDTLIGLDISGLGSRFAVAPHQLP
                     GAEGGGDWRRHWGALRLYPPDAFLLGRALVAPVPAREAEEGPRWPERYAGFAARVRVPV
                     RFTFAEQERWWRCDDEALAALRSPLAAPRVVIDHQPDAGHNISLGWAARTYHLRALAFL
                     EECLLARDVMFPAATEERDAALR"
     aSDomain        19363..19662
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS44355_Abhydrolase_1.1"
                     /evalue="4.70E-09"
                     /label="IE325_RS44355_Abhydrolase_1.1"
                     /locus_tag="IE325_RS44355"
                     /protein_end="138"
                     /protein_start="38"
                     /score="28.1"
                     /tool="antismash"
                     /translation="VVVAVHGGGMRAGYFDSRSRPGLSLLTLGAELGCTVLALDRPGYG
                     LSAARLPEGQTVEEQAAGLHAALADFATRHDTGAGFFVVAHSYGGKIALATAARE"
     gene            20192..20317
                     /locus_tag="IE325_RS46800"
                     /old_locus_tag="GCM10018780_90100"
     CDS             20192..20317
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE325_RS46800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10018780_90100"
                     /product="hypothetical protein"
                     /protein_id="WP_268256405.1"
                     /transl_table=11
                     /translation="MDENPDHQDQRGEQRTHPPRPAFLAGEDGERPDPHIFRGTD"
     gene            20327..21583
                     /locus_tag="IE325_RS44360"
                     /old_locus_tag="GCM10018780_90110"
     CDS             20327..21583
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008740569.1"
                     /locus_tag="IE325_RS44360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90110"
                     /product="MFS transporter"
                     /protein_id="WP_190075901.1"
                     /transl_table=11
                     /translation="MRATLAAAFQSLTIRNFRLFAAGQIVSVGGTWMMVVAQDWLVLSL
                     TGDSASALGMITALQFAPLLLFTLHAGGLADRYDKRRLLLAANLASALLALLLGALVLA
                     GAARLWHVALFALGLGLVNAVEVPARMSFVSELVGADLLPNASALSAAYFNSARVLGPA
                     VAGLLIGWCGTGPVMLLNAATYLATITALCLMRPAELHRSAHRPPRAPVTDGIRHVMTR
                     PDLLLPIALAAVVGMWGFNFQLTLPLLAKTVFHADATAFGLLTTSLAAGSLLAAFVTTL
                     RRGRPPLRRVIATAAGFGALELLSGLAPTFTTAAILLFLTGFASVTFAQSTNHRIQLGA
                     DPAYRGRVLALYTLVFQGTTPLGALLLGALTESLGARAGLLAGGAVTLLAAAIAHTIHR
                     TSAKAPAPTPHPPLDRKPS"
     misc_feature    21488..21490
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(21636..22211)
                     /locus_tag="IE325_RS44365"
                     /old_locus_tag="GCM10018780_90120"
     CDS             complement(21636..22211)
                     /GO_process="GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1296: tellurium
                     resistance protein, TerD"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057183.1"
                     /locus_tag="IE325_RS44365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90120"
                     /product="TerD family protein"
                     /protein_id="WP_190075902.1"
                     /transl_table=11
                     /translation="MAVSLSKGGNVSLTKEAPGLTAVTVGLGWDVRTTTGTDFDLDASA
                     IAVNPTGKVYSDGHFVFFNNKQTPDQTIVHTGDNRTGEGAGDDEAIKVNLAGLPADVDK
                     IVFPVSIYDAENRSQNFGQVRNAYIRIINQAGGAEIARYDLSEDAATETAMVFGELYRN
                     GAEWKFRAVGQGYASGLVGIAQDFGVNV"
     gene            22372..22806
                     /gene="arfB"
                     /locus_tag="IE325_RS44370"
                     /old_locus_tag="GCM10018780_90130"
     CDS             22372..22806
                     /EC_number="3.1.1.29"
                     /GO_function="GO:0003747 - translation release factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="arfB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019887427.1"
                     /locus_tag="IE325_RS44370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90130"
                     /product="alternative ribosome rescue aminoacyl-tRNA
                     hydrolase ArfB"
                     /protein_id="WP_190075903.1"
                     /transl_table=11
                     /translation="MYDMSGPYVIRGSVSLPEAELMWRFSRSSGPGGQHVNTSDSKVEL
                     SFDLAKTESLPEVWKARALQRLSTRLTDGVLTVRSSDHRSQWRNRETAAVRLAALLAEA
                     TAPPPKPRKPTRIPRGINERRLREKKQRAQTKRGRTGKDW"
     gene            23034..23915
                     /locus_tag="IE325_RS44375"
                     /old_locus_tag="GCM10018780_90140"
     CDS             23034..23915
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015659592.1"
                     /locus_tag="IE325_RS44375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90140"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_190075904.1"
                     /transl_table=11
                     /translation="MPTDDDTDYLAHRFEAHRSHLRAVAHRMLGSTTEAEDAVQETWFR
                     VSRTDTSTVDNLAGWLTTVTGRVCLDMLRSRKSRAEQPLDTTSPPPTPTAPTDPEQDAL
                     LADSIGVALLVVLDTLTPAERLAFVLHDLFAVPFEEIATVLDRTPAAARQLASRARRRV
                     QGAEPPEHDRTCTHRQRQVVEAFLAAAREGDFEGLLDVLDPDVVARTEAGVTTGAAAVA
                     RGASTFGSAALAARPALTVRHALIDGTTAVVALADGRLERALKFAFVRDRITVIDIVTA
                     PDRLARLDIDLI"
     gene            complement(23912..24430)
                     /locus_tag="IE325_RS44380"
                     /old_locus_tag="GCM10018780_90150"
     CDS             complement(23912..24430)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010035991.1"
                     /locus_tag="IE325_RS44380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90150"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_190075905.1"
                     /transl_table=11
                     /translation="MTSTTSDLRLEIITPANFDTATGIRVRPDQERVSSPVMQSLAEAY
                     VHPPGVAWPRLIVDGDRAVGFLMAFFDIDWHGDGSVRRSGLWRLNIDAREQGRGYGRFA
                     VESVGAEIRRRGGDLLYVTWHPGPGGPEGFYGGLGFRDTGETAEDEVVGVLDLGRVGRS
                     DTRSGPGGR"
     misc_feature    complement(24399..24413)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.93"
                     /tool="antismash"
     gene            complement(24501..25076)
                     /locus_tag="IE325_RS44385"
                     /old_locus_tag="GCM10018780_90160"
     CDS             complement(24501..25076)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160: flavin reductase domain protein FMN-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004986543.1"
                     /locus_tag="IE325_RS44385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90160"
                     /product="flavin reductase family protein"
                     /protein_id="WP_190075906.1"
                     /transl_table=11
                     /translation="MPNTSPAAQPSTSLLHAEGVSNDEFRAAMSRLAAGVVLVTALEPP
                     LDPDDPHAPAGEDVGMTATAFMSVSLDPPLVLVSLREGSRMDDLLAEQPLWAVSVLTES
                     QRHIAGRFAMKGRVSDRLLFADIPYVRGTESGAPLVGGALATLECRTEQRVPAGDHTLV
                     IGRVLSASLPSADGGPLTYFRGRYRQLG"
     misc_feature    25080..25091
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.5"
                     /tool="antismash"
     misc_feature    25196..25214
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.47"
                     /tool="antismash"
     misc_feature    complement(25259..25274)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    25283..25292
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.02"
                     /tool="antismash"
     misc_feature    25406..25424
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.68"
                     /tool="antismash"
     gene            25406..27061
                     /gene="cdgB"
                     /locus_tag="IE325_RS44390"
                     /old_locus_tag="GCM10018780_90170"
     CDS             25406..27061
                     /EC_number="2.7.7.65"
                     /GO_function="GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cdgB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011029551.1"
                     /locus_tag="IE325_RS44390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90170"
                     /product="diguanylate cyclase CdgB"
                     /protein_id="WP_190075907.1"
                     /transl_table=11
                     /translation="METESEPYVRLATLRQLHQVMADMNTARSLADTLQTVADGVVTGL
                     GYELACVNLVRPDGDLVVAAFAGNPAAEALITGRVGSRDSWERRLNMGEHWGDLVFIPH
                     TEGWILDDDDVPQWYTDGPAPRFEDEWHPSDRLFAPMYTPGVQGGACGELIGVLSVDRP
                     RNGRLPGAWGREALQMYAFQAAIAISNARLRANMQRALVRLERDQQALRASEESFRQAF
                     EYAPSGMAIAEMGGDQHGRILRTNDALCRLLGRPASAMRRYSFSDLVHPEDIGTLLRTS
                     AEGGRAELRLGRRDGTYVWVSLRNSVVADAADGPRFLLTHVEDIEERKRRELQLAHRAS
                     HDSLTGLPNSAELRARLSARLCRRAAHAGALESMDAAYGHPAVFDANGHGFDFPGAAAL
                     EAFDHHVHTVSPDEGERDDGTKGLAVLFCDLDGFKSINDRFGHNAGDAVLIEVARRLTR
                     QVRDGDTVARLGGDEFVILADGLGRADAADLAVRLRNEIIQPIRAEGRAVRVGASFGIG
                     WAHCGMTADEVLKSADERMYVEKRSRPKQHRRAG"
     misc_feature    27114..27132
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.4"
                     /tool="antismash"
     gene            27182..28120
                     /locus_tag="IE325_RS44395"
                     /old_locus_tag="GCM10018780_90180"
     CDS             27182..28120
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019523936.1"
                     /locus_tag="IE325_RS44395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90180"
                     /product="CBM35 domain-containing protein"
                     /protein_id="WP_190075908.1"
                     /transl_table=11
                     /translation="MTSGNNGASTPEDDDPFGYLYADGQANGAQPPSGGGGYGYPGSVN
                     RVRAVGQRQYGQQAPAPQIPQQQGTYGQPNAHYAAPETLPGGAPTTAQPAYSGGSGSGR
                     GGGPNTKGLLIGAIAVVAAVVIGISVAMLGGDDDKGNEADGSGSTPTQSQSAESSPSAS
                     SSAEEQAELPKIDAKALRLEGGATTASEFKGAKAEGGVYVTGFNQVGAKVTWTVNGIEK
                     AGTYRLYVHYGVPGKDADATLVVNGTAQSRVLNMENFGNTPEGDWEKGWKDTWSNVNLN
                     KGTNTITLACNDGNQCDAVLDQMYLTGESGN"
     gene            complement(28127..29056)
                     /locus_tag="IE325_RS44400"
                     /old_locus_tag="GCM10018780_90190"
     CDS             complement(28127..29056)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020140094.1"
                     /locus_tag="IE325_RS44400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90190"
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="WP_190075909.1"
                     /transl_table=11
                     /translation="MILTVTLNTALDITYRVPALRPHTSHRVTEVTERPGGKGLNVARV
                     LAALGHEVTVTGFTGGATGLVVQEQLTGTRGVVDALVPVTGPTRRTIAVVDAHTGDTTQ
                     LNEPGPTITPAEWSAFQEAYEDLLTSASAVALCGSLPPGVPVGAYAGLVRAAKAAEVPV
                     LLDTAGEALRRGVAARPDIIKPNADELAELTGSHEPLRATQDARRRGARAVVASLGRSG
                     LLALAPEGRWRAVPPASLHGNPTGAGDAAVAGLLSGLVEKLPWPDRLARAAALSAASVL
                     APVAGEFDRGTYEELLGRVAVSGEVSAA"
     gene            complement(29199..30434)
                     /gene="nagA"
                     /locus_tag="IE325_RS44405"
                     /old_locus_tag="GCM10018780_90200"
     CDS             complement(29199..30434)
                     /EC_number="3.5.1.25"
                     /GO_function="GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA]"
                     /GO_process="GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="nagA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016436702.1"
                     /locus_tag="IE325_RS44405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90200"
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="WP_190075910.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 2.2e-30, bitscore:
                     98.5, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAHPGARDSANMRLRRGARPATTHPHPATDKIPLILSGANVVTP
                     TGTVKDGEVIIDGTRIAAAAPENAHRIDLTGHHVVPGFVDIHNHGGGGASFTSGTPDDV
                     VKGIHTHRLHGTTTLVASTVTGDMDFLTRRAGLLSELAEQGDIAGIHFEGPFISPCRKG
                     AHSEELLRDPDPAEVRKLIDAARGHAAMVTLATELPGGIDSVRLLAEHGVIAAIGHTDA
                     TYEQTVAAIEAGATVATHLFNAMPPLGHREPGPIAALLEDERVTVELINDGTHLHPAAL
                     QLAFHHAGADRVAFITDAMDAAGFGDGRYMLGPLEVEVADGVARLVEGGSIAGSTLTLD
                     RAFKRAVTVDRLPVEHAVSALSANPAKLLGRYDRIGSLEPGKDADLVILDSAFDLKGVM
                     RRGEWVVDPQLG"
     gene            complement(30434..31378)
                     /locus_tag="IE325_RS44410"
                     /old_locus_tag="GCM10018780_90210"
     CDS             complement(30434..31378)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004000243.1"
                     /locus_tag="IE325_RS44410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90210"
                     /product="ROK family protein"
                     /protein_id="WP_190075911.1"
                     /transl_table=11
                     /translation="MRHVIALDVGGTGMKAALAGTSGELLHQARRPTGRERGPDAVIDG
                     ILDFAAELRAYGEERFGEPAVAAGVAVPGIVDEQRGIAAYAANLGWRDVPLRRLLSERL
                     GGIPVALGHDVRTGGLAEGRIGAGRGADRYLFVALGTGIAGAIGVDGRVESGAHGFAGE
                     IGHIVVRPGGAPCPCGQHGCLERFASAAAVSEAWAAAVGDPEVDAADCAKAVTSGDPNA
                     VRVWQNAVDALADGLVTALTLLDPRTLIIGGGLAEAGETLFTPLRDAVRSRVTFQKLPS
                     IVPAALGDTAGCLGAGLLAWDLLDQTDRTEESA"
     misc_feature    31407..31422
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.89"
                     /tool="antismash"
     misc_feature    31425..31440
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.61"
                     /tool="antismash"
     misc_feature    31461..31475
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.79"
                     /tool="antismash"
     gene            31552..32787
                     /locus_tag="IE325_RS44415"
                     /old_locus_tag="GCM10018780_90220"
     CDS             31552..32787
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016326855.1"
                     /locus_tag="IE325_RS44415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90220"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_229912533.1"
                     /transl_table=11
                     /translation="MSALGLTAALGGCGLTGDSGGVTLRLVAADYGDSESNSSQKYWDK
                     LVEAYEAEHPGVTVDVTVYSWSDVDAKVKEMVDAGKAPDMAQIGAYADYAAKGLLYEAD
                     ELLSIPVQADFVAQFADAGQVKSVQYGIPFASSTRLLFYNKTLFQKAGLDAPKTWKELA
                     ADAEALKAQGVKYPYALPLGPEEAQAETMQWLLSGGGGYTDNASGTYSIDSAENVATFN
                     WLKNDLVGKGLTGPVAPGKLNRAAAFSAFADGDVGMLNGHPSLMQTAAKKGVKFGMVPM
                     PGVDGPSKVSMGVADWMMAFKENGHADEVGDFLDFVYDKQNVLDFSREYNLLPVTNSAS
                     TVMTAADEDADLKPFLEELPLSELYPVGRTSWAAISADVKKRIGGTVAAGGSPSAILGQ
                     LQLAATRAESAE"
     gene            32824..33069
                     /locus_tag="IE325_RS44420"
                     /old_locus_tag="GCM10018780_90230"
     CDS             32824..33069
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007493262.1"
                     /locus_tag="IE325_RS44420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90230"
                     /product="DUF3263 domain-containing protein"
                     /protein_id="WP_190075913.1"
                     /transl_table=11
                     /translation="MDQDPTKPALADRERAILALERRGFTGPGAKERAIREELGLAPVR
                     YYQLLNALLDDPRALEHDPVTVNRLRRVREVRRGER"
     misc_feature    complement(33199..33208)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.26"
                     /tool="antismash"
     gene            33260..34135
                     /gene="otsB"
                     /locus_tag="IE325_RS44425"
                     /old_locus_tag="GCM10018780_90240"
     CDS             33260..34135
                     /EC_number="3.1.3.12"
                     /GO_function="GO:0004805 - trehalose-phosphatase activity
                     [Evidence IEA]"
                     /GO_process="GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="otsB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013002665.1"
                     /locus_tag="IE325_RS44425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90240"
                     /product="trehalose-phosphatase"
                     /protein_id="WP_190075914.1"
                     /transl_table=11
                     /translation="MDSHKDLPTPTTQPGRDGLAALLARPSRALIALDFDGTLAPIVPD
                     PEQARAHPDALPALAALAPKVAAVAVVTGRPADVAVRYGGFGGVPGLEHLVVLGHYGAE
                     RWDAVSGKVTAPDPHPGIAAVRAELPALLEGHGTWIEDKGHAVAVHTRRAADPQGTFDA
                     LRAPLTDLATRNGLIVEPGRMVLELRPPGMDKGVALSRYVRELGVESVLYAGDDLGDLP
                     AYAAVEALRSDGTFGVLVCSGSEEVTELSQRADVVVDGPEGVVRLLRAIADQVDRGPGP
                     GSDPSSSARN"
     gene            complement(34078..35484)
                     /locus_tag="IE325_RS44430"
                     /old_locus_tag="GCM10018780_90250"
     CDS             complement(34078..35484)
                     /EC_number="2.4.1.15"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007493264.1"
                     /locus_tag="IE325_RS44430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90250"
                     /product="trehalose-6-phosphate synthase"
                     /protein_id="WP_190075915.1"
                     /transl_table=11
                     /translation="MASKVLVASNRGPVSYSVGEDGSLHSKRGGGGVVSGLSAIGPDAG
                     ALWVCSALSDGDREAVRRGAGEEGVRMLPIPADVHADAYNGIANSVLWFVHHMLYQTPL
                     EPVFDAEFRRQWAAYETYNRAFAQALAAEAAPGAAVLVQDYHLCLVPGMLRDLRPDLRI
                     GHFSHTPWAPADYFGMLPDDIRTQLLRGMLGADRLGFLTRRWADAFEACAERFAGGLGG
                     TRVGVHGLGADADFLRARAHQADVAERMEALRDEIGEGRKTIVRVDRTELSKNIARGLL
                     AYGQLLDDHPEWREKVVHVAFAYPSRQDLAVYRDYTAEVQRLATEINSRYGTPDWTPVV
                     LHVKDDFARSLAAYRLADVALVNPIRDGMNLVAKEMPVLSDEGCALVLSREAGAFEELG
                     EDAIPVNPYDVIDTARALHEALTMRPEERAERSKRLAAAATALPPAQWFLDQLRALEEG
                     SEPGPGPRST"
     misc_feature    35516..35529
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.58"
                     /tool="antismash"
     gene            complement(35580..36524)
                     /locus_tag="IE325_RS44435"
                     /old_locus_tag="GCM10018780_90260"
     CDS             complement(35580..36524)
                     /EC_number="2.4.1.266"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016436696.1"
                     /locus_tag="IE325_RS44435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90260"
                     /product="glucosyl-3-phosphoglycerate synthase"
                     /protein_id="WP_190075916.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.2e-12,
                     bitscore: 39.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEEAERWLSTRSWSAADRPVHQILAAKQRTGQSVSVVLPALDEE
                     ETVGDIVAVIVHDLVRQIPLVDEIVVVDSGSTDRTSEVAAAAGARVVHRDAILPRIPAV
                     PGKGEVLWRSLLVTTGDIVCFIDADLREFSSEFVSGIVGPLLTDPGVDLVKAMYDRPLG
                     GAAGQGGRVTELMARPLLNMHWPQLAGFVQPLGGEYAARRSLLEQLPFPVGYGVELGML
                     VDALHLVGLDALAQVDVGVRKHRHQDGQALGRMSAAIYRTAQLRLARGHLVRPSLTQFE
                     RGGDGFEPRTYSVDTEERPPMVEIAEYATRKVA"
     regulatory      36654..36800
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            36819..38105
                     /gene="thrC"
                     /locus_tag="IE325_RS44440"
                     /old_locus_tag="GCM10018780_90270"
     CDS             36819..38105
                     /EC_number="4.2.3.1"
                     /GO_function="GO:0004795 - threonine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thrC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007382897.1"
                     /locus_tag="IE325_RS44440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90270"
                     /product="threonine synthase"
                     /protein_id="WP_190075917.1"
                     /sec_met_domain="PALP (E-value: 2.3e-64, bitscore: 210.1,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAQTVASTTESTVDLGPAAALSCRECGHRVPLGPVFACEECFGP
                     LEIAYDFSAYDAEELRKRIEAGPANIWRYAPLLPVPADVATKPNINPGWTQLVKADNLA
                     RELGVDTGKLFIKDDSGNPTHSFKDRVVAQAIEAARAFGFTTLSCSSTGNLAGAVGAAA
                     ARAGFRSCVFIPHDLEQGKVVMAAVYGGELVGIEGNYDDVNRFCSELIGDPAGEGWGFV
                     NVNLRPYYAEGSKTLAYEICEQLGWQLPDQLVVPIASGSQLTKIDKGLQELIKLGLVED
                     KPYKIFGAQAEGCSPVSTAFKAGHDVVRPQKPNTIAKSLAIGNPADGPYVLDIARRTGG
                     FVEDVTDTQVVEAIKILARTEGIFAETAGGVTVGVAKKLIENGVLDPTKTTVVLNTGDG
                     LKTLDAVAGTGLTATIRPNLDSFREAGLA"
     gene            38102..38377
                     /locus_tag="IE325_RS44445"
                     /old_locus_tag="GCM10018780_90280"
     CDS             38102..38377
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010985363.1"
                     /locus_tag="IE325_RS44445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90280"
                     /product="MoaD/ThiS family protein"
                     /protein_id="WP_190075918.1"
                     /transl_table=11
                     /translation="MSVTVRIPTILRTYTGGQAEVAAEGANLGEVISDLEKNHTGIAAR
                     VLDDQGKLRRFVNVYVNDDDVRFEQGLETATPDGAGVSIIPAVAGG"
     gene            38830..39036
                     /locus_tag="IE325_RS44450"
                     /old_locus_tag="GCM10018780_90290"
     CDS             38830..39036
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967346.1"
                     /locus_tag="IE325_RS44450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_90290"
                     /product="cold-shock protein"
                     /protein_id="WP_016436693.1"
                     /transl_table=11
                     /translation="MAQGTVKWFNAEKGYGFIAVDGGADVFVHYSAIQMDGYRTLEEGQ
                     RVDFEISQGQKGPQADMVRLAAG"
     misc_feature    complement(38878..38891)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    39224..39239
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.7"
                     /tool="antismash"
     misc_feature    complement(39227..39242)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.11"
                     /tool="antismash"
     misc_feature    40597..40606
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
ORIGIN
        1 aggtcgccga gctgtactcg tcctcgaagg cgatcctgaa ggaggccggg tacgtcggcg
       61 ccggcacggt ggagttcctg gtcggcctgg acggcacgat ctccttcctg gaggtcaaca
      121 cccgtctgca ggtggagcac ccggtcaccg aggagatcgc cggcatcgac ctggtgcggg
      181 agatgttccg catcgccgac ggtgaggaac tcggctacgg cgacccggtc ctgcgcgggc
      241 attccttcga gttccgcatc aacggcgagg accccggccg aggcttcctc cccgcccccg
      301 gcaccgtcac gaccttcgcc ccgccgtccg ggcccggtgt ccgcctggac gccggtgtcg
      361 agtccggcag cgtgatcggc ccggcctggg actccctgct cgccaagctc atcgtcaccg
      421 gcgcgacccg cgaacaggcc ctccagcgcg ccgcccgcgc cctggccgag ttccaggtcg
      481 agggcatggc caccgccatc cccttccacc gcgccgtcgt caccgacccg gcgttcaccg
      541 gcgaaccgtt caccgtccac acccggtgga tcgagaccga gttcgccaac accatcaagc
      601 ccttcgccgc tcccgccgac aacgacgccg acgaggagac cggccgggag agcgtcgtcg
      661 tggaggtcgg cggcaagcgc cttgaggtct ccctcccgtc ctccctcggc atgaccctgg
      721 cccgcaccgg cctcgccgca ggggccaagc ccaagcgccg ggccgccaag aagtccggcc
      781 ccgccgcctc cggcgacacc ctcgcctccc ccatgcaggg caccatcgtc aaggtcgccg
      841 tcgaggaagg ccaggaggtc gaggaaggcg acctcatcgt cgtactcgaa gccatgaaga
      901 tggaacagcc cctcaacgcc cacaaatccg gcaccatcaa ggggctctcc gccgaaatcg
      961 gtgcttccct cacctccggc gccggaatct gcgaaattat gggctgagtc accatgtaat
     1021 tccgtgcgca catttcaggg atcccccggc agtctgccgg gggatttttc tttgtggtgc
     1081 tgagctgcgg gttttcctgg ctctgacgct cgcctcacct gcttttttca gggatgtagt
     1141 tgcgcgctga gatctcaccg agacctgaat ggatgcgcat tgaatccccc ttggtgaacg
     1201 aagaggatta gtactgcttc gccgatccgt gctgagcggc acctgagata tccgaggaga
     1261 ggtaaatgga tgctgcagtg attgttgtcg gcgcgggtcc cgccgggatg atgctggccg
     1321 gcgaactgcg gctcggggga gtcgatgtca tcgtcctgga gcggctgacc gagcgcaccg
     1381 gggagtcgcg agggctggga ttcaccgcgc gcaccatgga ggtcttcgac cagcggggga
     1441 tgcttccccg gttcggggag atcgagacca gcaaccaggg ccacttcggc ggtctgcccg
     1501 tcgacttcgg tgtgctggaa ggggcttggc aggcggccaa gaccgtgccc cagtcggtca
     1561 ccgagcagca cctggaggag tgggcgagca gcctgggcgc cgacatccgg cgcggtcatg
     1621 agttcctgtc cctgaaggac gagggcgacg ccgtcgaggt cgaggtgcgg ggccccgagg
     1681 gtgtgcaccg gctgcgggcc gcctacctgg tgggctgtga cggcgggcgc agcgccgtac
     1741 gcaaggccgc cggtttcgac ttccccggca ccgcggcgac gatggagatg ttcctcgccg
     1801 acctcaaggg cgtcgacatc cagccccgca tgatcggtga gaccctgccc ggcggcatgg
     1861 tgatggcggg cccgctgccc ggcgacgtca cccgcatcat cgtctgcgag cgcggcaccc
     1921 cgccccagcg ccgggaggtc ccgccgtcct tcgaggaggt cgcggacgcc tggaagcggc
     1981 tcaccggcga cgacatctcg cacgccgagc cggtctgggt cagctccttc ggggacgcga
     2041 cccgccaggt caccgagtac cggcgcgggc gggtcatcct ggccggcgac tccgcgcaca
     2101 tccatctccc ggccggcggc cagggcatga acaccagcat ccaggacgcc gtcaacctgg
     2161 gctggaagct cgccgccgag gtgcggggct gggcgcccgc ggggctgctg gacacgtatc
     2221 acagcgagcg gcacgccgtc ggcaagcgac tgctgatgaa cacccaggcc caggggctgc
     2281 tgttcctcag cggtcccgag gtgcagccgc tgcgcgatgt gctgaccgaa ctcatcggct
     2341 accggaacgt cgcccagcat ctggccgcca tggtgagcgg cctggagatc acctacgacg
     2401 tcggcggcgg cagccacccg ctgctcggca ggcgtatgcc gcagctggag ctggccgcct
     2461 cggtgcgcgc gaccagcagc accgaactgc tgcactctgc ccgggggttg ctgctcgacc
     2521 tggaggacaa cccgcggctg cgggccaggg ccgcggcctg ggccgaccgg gtggacaccg
     2581 tcaccgccga gcccggcgcg gtcacggagg ccggcggact gcggggcacc tcggccgtgc
     2641 tggtccgccc cgacggccat gtcgcctggg ccgcgcccgg cagccaccac gacctgggca
     2701 tggccctgga gcgctggttc ggcgcgcccc gcacatgagc accggcaggc ccggccccac
     2761 cgtcgatcca cggaagagag aagacatgca cagcaccctg atcgtggccc ggatggacat
     2821 cgagtcgagt gccgaggtcg gcaggctctt cgcggagttc gacaggaccg agatgccgca
     2881 tcgcatgggc acccggcgcc gtcagctgtt cgcctacaag ggcctgtact tccacctcca
     2941 ggacttcgac gccgacaacg gcggagaact gatcgaggac gccaagaccg acccgaggtt
     3001 cgtgcagatc agcgacgacc tcaagccgtt catcgaggcg tacgaccccg cgacctggcg
     3061 gtccccggcc gatgccatgg ccacccgctt ctacgactgg acggccgaca cgacgggagg
     3121 ccaccgctag tggcacgccg ggtagtgatc acaggagtcg gagtgctggc gccgggcggt
     3181 atcggtgcca agaacttctg gagtctgctg agcgagggcc gcacagcaac cagggggatc
     3241 accttcttcg acccttccgc attccgttcc agggtcgcgg cggaggtcga cttcgacccg
     3301 tatctgcaag ggctgagccc gcaggagatc cgccgtatgg accgcgcggc ccagttcgcc
     3361 gtggtcaccg cccgtgaggc gctcgcggac agcggtctcg acctcggcgg gttcgacccg
     3421 caccgcaccg gggtcaccat cggcagcgcg gtcggcgcga ccaccgggct cgacgacgag
     3481 taccgggtgg tcagcgacga cggccggctg gacctcgtcg accacaccta tgccccgcag
     3541 cacctgtaca actacttcgt cccgagctcg ttctcggccg aagtggcctg ggccgtgggc
     3601 gccgagggcc cggccgccgt ggtctccacc ggctgcacct ccggcatcga ctcggtcggc
     3661 cacgccgtgg acctgatccg cgagggcacc gccgacatca tgatcaccgg cgcgacggac
     3721 gcgccgatct cgccgatcac catggcctgc ttcgacgcga tcaaggcgac caccccgcgc
     3781 aatgacgacc ccgagcacgc ctcgcggccc ttcgacggca cccgcaacgg ctttgtgctc
     3841 ggcgagggtt ccgccgcgtt cgtcctggag gagctggaca gcgcccgcag gcgcggggcg
     3901 cacatctacg ccgagatagc cgggtacgcc tcccgctgca acgccttcca catgacgggg
     3961 ctgcgtcccg acggccggga gatggccgag gccatcacgg tggcgctggg cgaggcgcgg
     4021 atgaaccccg aggccgtcga ctacatcaac gcgcacggct cgggcaccaa gcagaacgac
     4081 cggcacgaga cggccgcgtt caagctgagc ctcggcgacc acgcctatcg caggccggtg
     4141 agctccatca agtcgatggt gggccactcg ctgggtgcca tcggctccat cgagatcgcc
     4201 gcctccgtgc tggcgatgga gaaccacgtg gtgccgccca ccgccaatct gcacaccccc
     4261 gaccccgaat gcgacctcga ctacgtgccg ctcaccgcgc gggagcaccg gaccgacacg
     4321 gtgctcacgg tcggcagcgg attcggcggg ttccagagcg cgatggtgct ggcccgtccc
     4381 gacaggagcg tgtcatgagc accagcacca ggaccgtgat caccggcatc ggcgtggcca
     4441 cccccagcgg gctcggcatc gacgacttct gggccgcgac ccgcgtcggc aagaacgcca
     4501 tcggccgcgt cacccacttc gacccgacgt cgtacccgtc ccgactggcc ggtgagatac
     4561 ggcacttcgc cgccgaggaa ctgctgccca gcaggctgat cccgcagacc gaccggatga
     4621 cccggctcgc gctggtcgcc gcggactggg cgttcgcgga cgcgggcatc aagcccggcg
     4681 acatccccga gttcgacatg ggcgtcgtca ccgcctcgac ctccggcggc ttcgagttcg
     4741 gccagaacga gctgaagaaa ctgtggagcc agggcagcca gtacgtcagc gcgtaccagt
     4801 ccttcgcctg gttctacgcc gtcaacagcg gccagatctc catccgcaac ggcatgcgcg
     4861 gccccagcgg tgtcgtcgtc agcgaccacg ccggcggtct cgacgcgatc gcccaggccc
     4921 ggcggcagat ccgcaagggc agcaaggtga tcttctccgg cggcttcgac gcgtcgatct
     4981 gcacctgggg ctgggtcgcg cagatcgccg gcggccgcat gtccaccagc gacgatcccg
     5041 accgggcctt cctgccgttc gacgcggacg ccgacggcta tgtgcccggt gagggcggtg
     5101 ccctgctcgt cctggaggac gaactgacgg cccgtgagcg cggcgcgcgg acggtctacg
     5161 gcgagatcgc cggctacggc tcgaccttcg acccgaagcc cggcagcggc cgtgagcccg
     5221 gtctgcgccg cgccatcgag gtggcgctcg cggacgccgg cgtcgagacc ggggaggtcg
     5281 acgtggtgtt cgcggacgcc gccggcaccc cgcgactgga ccgcgaggag gccgacgcga
     5341 tcaacgccgt cttcgggcgg cacggcgtcc cggtcaccgc gcccaagacg atgaccggcc
     5401 ggctctactc cggtgccgcc ccggtggacg tggtctccgc cgtactggcc atccgcgagg
     5461 gcctgatccc gcccaccgtg aacgtcgagc cgtcccccga gtacggcatc gacctggtga
     5521 ccgcccagcc gcgcagcgcc tcggtgcgca ccgcgctggt cctcgcccgt ggccacggcg
     5581 gctacaactc cgccgtggtg gtccgggccg tggactgacc ccggctcacc gacacaaccg
     5641 acccaccgac gaaaggaccc ccatgtccga gcggaaattc accttcgacg ccctcaagcg
     5701 catcctgcgc gagggcgcgg gcgccgacga gggcgtcgac ctcgacggcg acatcctcga
     5761 cgccgacttc gaggagctgg gctacgagtc gctggcgctg ctggagaccg gcggccggat
     5821 cgagcgcgag tacggcatct ccctcgacga cgacatcttc accgaccacc gcaccccgcg
     5881 cgccctcgtg gccgccgtca acgagctgct caaggacaac accgtcagcg ccgcctgacc
     5941 cccgcgccgt caccgctcag cactggagag agacatgtcg cagcaggaca agccggtcgc
     6001 cctcgtcacc ggagcgacca gcggaatcgg gctcgccgtc gcccgcctcc tggcctccgg
     6061 cggccaccgg gtgttcatcg gcgcccgcaa cgccgagaac ctcgccgcca ccgtcaagca
     6121 actgcaggac gacggcctgg aggccgacgg aaccaccctg gacgtgcggt cggtcgagga
     6181 ctgccgggcg ttcgtgcggg ccgccgtgga gcgcttcggc accgtggacg tgctggtcaa
     6241 caacgcgggg cgcagcgggg gcggggtcac cgccgacatc gccgacgagc tgtgggaaga
     6301 cgtcatcgac accaacctca acagcgtctt ccggatgacc cgagaggtgc tggagaccgg
     6361 cgggatgcgg cacaaggacc gcggccggat catcaacatc gcctccaccg cgggcaagca
     6421 gggcgtcgtc ctcggggcgc cgtactccgc gtccaagcac ggcgtcgtcg gcttcaccaa
     6481 ggccctcggc aatgagctgg cccccaccgg catcaccgtc aacgccgtct gccccggcta
     6541 tgtggagacc ccgatggcgc agcgcgtccg gcagggctac gcggccgcgt acgacaccag
     6601 cgaggacgcg atcctggaga agttccaggc gaagatcccg ctcggccgct actccacccc
     6661 cgaagaggtg gccggactcg tcggctatct gacgtccgac agcgccgcct cgatcacctc
     6721 ccaggccctc aacgtctgcg gtggcctcgg caacttctga aaccgcccga ccccgaaccc
     6781 gaggagtatg agcatgccga agcccggccc gcgcgaggtg gagcacgaga tcacggtctc
     6841 ggcgccggcc accgccgtct accggctgat cgccgaggtg gagaactggc cgcggatctt
     6901 cccgccgacc atccacgtcg accatgtcga gaagggcgac cgcaccgaac gtatccggat
     6961 ctgggccacc gccaacggcg aggcgaagaa ctggacctca cgccgcaccc tcgaccccga
     7021 ggagctgcgg atcggcttcc gccaggaggt ctccgcgccg ccggtcgccg agatgggcgg
     7081 cacctgggtg atcgagccgg tctccgacac cgtctcccgg atacggctgc tgcacgacta
     7141 ccgggccgtg gacgacgacc cggccgggct ggcgtggatc gacgaggccg tcgaccgcaa
     7201 ctcccgcagc gagctcgccg cactcaagga gaacgtcgaa cgcgccgtcg ccagcgagga
     7261 gttgacgttc tccttcgagg acacggtgca gatcgccggc tccgccaagg atgtctacga
     7321 cttcgtcaac gacgcccatc tgtgggccga gcgcctcccg cacgtggcca gcgtccggct
     7381 cgacgaggac acccccggcc tgcagacgct ggagatggac acccgggcca aggacggctc
     7441 cacgcacacc accaagtcct accgggtgac cttcccgcac cggaagatcg cctacaagca
     7501 ggtcaccctg ccggcgctga tgaccctgca caccggttac tggacgttcg ccgagaacga
     7561 cgccggggtg gcggcgtcct cgcagcacac cgtcaccatc aacaccgaga acatcacccg
     7621 cgtactcggc gccgacgcca ccgtcgccga cgcccgcgag tacgtccagg ccgccctgag
     7681 caccaacagc cgggccaccc tcgggcacgc ccgggactac gcggaagcca gggcctgacc
     7741 atggccgggg accgtatcgc gaccgatgtg atcgtggtcg gcgcgggccc cgtcgggctg
     7801 atgctcgccg gggaactgcg cggggccggc gcggacgtgg tggtcctcga gaagctcacc
     7861 gcgccgacca ccgagtccag ggcgtccact ctgcacgccc ggaccatgga gatcctcgag
     7921 agccgcggcc tgctggcgcc gctcggcgac ataccgaacg accgcagagg ccacttcggc
     7981 ggcatccccc tcgacctcac cctgcccggc cgccacccgg gccagtggaa ggtcccgcag
     8041 acccggatcg aggaactgct cggacagtgg gcgcgcggcc tgggcgcgga catccggcgc
     8101 ggtcacgagc tgaccgggct gaccatgacc gccgaccacg tcgaggccgc cgtacgcctc
     8161 ccggacggga cgacgacgtc cctgcgggcc gggtacgtcg tcggctgcga cggtgagcac
     8221 agtgccgtac gccgcctggg cggcttcgac ttccccgggt ccgacgccga gcgtgagctg
     8281 ctgcgggccg acgtggccgg gatcgacatc cccgaccgcc gcttccagcg gctggcgggc
     8341 ggactcgcca tcgccgcccg gcgtcccgac ggagtgaccc gggtgatggt gcacgagttc
     8401 ggggcccggc cgcgcggcgg gcagcccggg ttccaggaca tcaccgacag ctggaagcgc
     8461 gtcaccgggg aggacatcgg ccatggcacc ccgctgtggg tgaactcctt cggcgacgcc
     8521 tcccggcagg ccgcccgcta ccgcgaccac cggctgctcc ttgccgggga cgcggcccac
     8581 cagaagatgc ccatcggcgg acaggccctc aacctgggcc tccaggacgc cgtcaacctc
     8641 ggctggaaac tggccgccga ggtccgcggg cgggcccccg agggcctgct cgacagctac
     8701 cacgacgaac ggcacgccgt cggccgccgg acgctgaaca acatccgggc ccaggccctg
     8761 ctgctgctcg gctccgccga ggtcgaggcg gtccggcgga tctacgccga actggccgcc
     8821 ggaagcgaga acgtacgcac ccacctggcc ggaatgatct ccggcctgga catccgctac
     8881 gacgtcggag gcggccggca tcccctgcag ggccgccgcc tggcacagcg ggacctgttc
     8941 cgcgcggggc gcggcctgct gctgctcacg ccgggcgcgg aggagctgcg cacggtcgcc
     9001 gcgccctggg gagacctcgt ggacacggcc gccgccccgc ccggggacgt accgccggac
     9061 ctgggcgcgg tcctggtccg cccggacgga cacgtggtgt ggacggacgc cgaggacacc
     9121 gccatcacga cagccctgac ccgctggttc ggcacgccga agcggcagtc cgacaggacg
     9181 acgacgagga atcggagtac agacatgagc agcaggctca cgggcaggac cgcgctcgtc
     9241 accggagcga gccgcggcat gggacgggcc accgccctgc gcctcgcaca ggagggcgcg
     9301 ctcgtcgccg tccactacag caccagcgag gaggcggccg aggaggtcgt cgagctgatc
     9361 gagaaggacg gcggccgggc cttcgccgta cgcgccgaac tgggcgtcgc cggtgatgtc
     9421 cacgagctgt tcctgggcct ggagaacggg ctccgggagc gcaccgggac cacggacctc
     9481 gacatcctgg tcaacaacgc cggtgtcatg ggcggcgtca agcccgagga caccacgccg
     9541 gaacagttcg accggctctt cgccgtcaac gccaaggcgc cgttcttcct gatccagcgg
     9601 gccctgaaga acatgcgcga cggtggccgc atcatcaaca tcacctccgg cctcacccgc
     9661 ttcgcgaacc cggacgagat cgcgtacgcc atgaccaagg gcgccgtgga ccagctcgcc
     9721 ctgcacttcg cgaagctcct cggcccgcgc aacatcaccg tcaacagcgt ggcgcccggc
     9781 atcacgcgca acggcaaccc ggtgttcggc ataccggagg cggtggagca gatggcgcag
     9841 ctgtccgcgt tcaaccgggt cggcgaaccg gaggacgtcg ccgacgtggt ggccttcctc
     9901 gccaccgacg aggcccgctg gatcaccggc tccttcgtcg acgccaccgg gggcaccctg
     9961 ctcggctgag ccggcggggg gcgtgcgccg ccccccgccc cgctgtcacc gacccctacg
    10021 gcggaacggg accatgacct cttcgacgcc ttccccgacc ctcacggccg gcgagcgctt
    10081 cagccccgcg ctatgggcgc tgctcttcgt gctcgcgggc aacatgctca tcgacgccct
    10141 ggaggtgtcc gtcgccctgg tggcgctgcc cgccgtgagc gacgacctcg ccctgtccgt
    10201 gccgcaggca cagtgggtgg tcagtggatt cgccgtcggc ttcggcgggt tgctgctgtt
    10261 cggctcccgc ctggtcaccc tcctcggccg ccgccgggtc tatctcgccg ccctgctgct
    10321 cttcgccgtc gcgtccctcg cgggcgccgc cgcggcgagc gggcccctgc tcatcggcac
    10381 ccgcctggtg aagggcttct gcgccgcact gaccgcgccc accgggctcg ccatcatcct
    10441 cgcggtgttt cccgaggggc ccgtgcgcgc cagggcggtg tcggtgtact ccttcttcgg
    10501 ggcggccggc ttctccgccg gtctgctgct gtcggggctg ctcaccgaga cgagctggcg
    10561 ctgggcgttc gcgttccccg cgccggtcgt gctgctgctg ttcgttgtcg gaatacgccg
    10621 cattccacgc gacgagcccg cctgggacac cgagggacgg tacggcgtcc cgagcgcgct
    10681 cggcctcatc ggcgccacgc tgctgctggt gtacgcgatc gtctcggtgc ccgccaccgg
    10741 ctggacgcat ccgaggacgc tcggcgcgtt cgtcctggcg gcattgtgcg cggcggtcca
    10801 tgtccgagcc gaactaacag cagccaagcc cctgttgagc ctggacctgc tccgtcacgc
    10861 cgccctggtc cgctccgcgc tgggcgccgc cgcgctgaac ggctcgtatc tgggcctgct
    10921 cctgctgagc acgctgcacc ttcagcagcg ggcgggttgg agcccgttgc agaccgggct
    10981 cgccttcctg ccggccagcg tcccgctcgc cctgaccgcc ctgcactccg gccgcctcgc
    11041 cgcccgcttc ggcccggcaa ggctgatcgc ggccggcgcc gcggcggccc cggccggcta
    11101 tctgctctac ccgcgcgacg ctcccacgca ggtggactac gtcatcgacg tactgcccac
    11161 gatgctgctc gtgggcaccg cgttcgtcct cgccttcgcg gccttccatc tccaggccac
    11221 cagctcggtc cccgcacccc gccaggcgga ggcgagcggc ctctaccaga ccgccgtcca
    11281 actgggcgcc gccctcatgc tcgccctgac ctcagcgctg tacggggcgg gttatggcgc
    11341 cgcgctgacg ctgatcacgg ctgtcggtgc gctgggcttc gcggtggctg tgagcgggtt
    11401 gctgccgggg cgacgggggg tgggacggtg agcactgccg aaccccgccc tccgcagacc
    11461 cagttcaccc tcggccccga ccggctcgac ctctacttgg tgcgcacccc gcagggccgc
    11521 gaggccgcgc tgctcgaccg ctccgagctc gatgacgccg aacgacgcag ggcgggctcc
    11581 ttccggcacc cggcgcacgc gctgctctac accaccgccc acatcgcgct gcgccggctg
    11641 ctcggccgtc agctgggcgt cgcgccacgc gacctgcggt tcctccggga gccctgtccc
    11701 ggctgcggtg cgccacacgg gcggcccgcc gtcgcgatgg ccggaccgcc cctgcacttc
    11761 tcgctctcgc acagcggcgg cctcgtcctc atcggcgtgg cggccgtcgc cgtcggtgtg
    11821 gacgttcagc ggctgccgcg cgaggagacc gtcgaggtcg cctcggctgc gctgcatgcg
    11881 ggggagcggg ccgaactcgg gcggcgggtg cggggtgcgg acaggacagg gcacttcggc
    11941 cggctgtgga cccgcaagga ggcgtacctc aaagcgatcg gcacggggct ccaccgctcc
    12001 ccggcccgtg actatctcgg cgccgacagc gccgtgcatc cgcccggatg gacggtgctc
    12061 gacgtggcct gccccccgac gcactccgcg gcggccgtcg tacgcgggcg gcgtccccgg
    12121 ttcgtcgacg tccaccggct cgacgggcgg tggctgtgca ccccggacac cccggacgcc
    12181 ctggccatcg ccaccaccat cagcacccac ggagaggtca ccacctgatg ctcaccgaag
    12241 acagcctcat gcatcgcacc gaagaactga ccgcgatcaa ggagtcggcg cggggcggac
    12301 ccgacccggc cgccaccgaa cgccagcacg ccaagggcaa gctgaccgcc cacgaacgta
    12361 tcgaactgct cctggacaag gggtcgttca ccgaggtcga gcctctgcgg cggcaccggg
    12421 cgagtggctt cgggcttgag cacaggaagc cgtacagcga cggtgtcgtc accggctggg
    12481 gcacggtcca cggccgtacc gtcttcgtct acgcgcatga cttccggatc ttcggaggcg
    12541 cgctcggcga ggcgcacgcg cagaagatcc acaaggttct ggatctggcc gaggcggccg
    12601 gtgcccccgt ggtcagtctc aacgacggtg ccggggcccg gatccaggag ggcgtcaccg
    12661 cgctggccgg gtacggcggc atcttccagc gcaacaccag gtcctcgggc gtcatcccgc
    12721 agatctcggt gatgctcggc ccctgcgcgg gcggcgccgc ctacagcccc gcgctcaccg
    12781 acttcgtgtt catggtccgt gagacctcgc agatgttcat caccggcccc gacgtcgtca
    12841 ggaccgtcac cggcgaggag atcacccaga acggcctcgg cggcgccgac gtgcacgccg
    12901 ccgtctcggg cgtcgcgcac ttcgcctacg acgacgagga gcactgcctg gaggacgtgc
    12961 ggtatctgct gtcgctgctg cccgccaaca accgggagct gtcacccgtc gtgccgtgcg
    13021 ctgatccggc cgaccggccc ggcgacgtgc tgctcgacct cgtgcccgcc ggatcggggc
    13081 aggcgtacga catccgcaag gtcatcgagg agatcgtcga cgacggcgag ttcttcgagg
    13141 tgcacccggc ctgggccacc aacctcgtgt gcgccctgac ccgcctcgac ggccatgtcg
    13201 tgggcgtcgt cgccaaccag cccgcttcca tggcgggcgt gctggacatc gaggcctccg
    13261 agaagggggc gcggttcgtc cagttctgcg acgccttcaa cattcctctg gtcaccctcg
    13321 tcgacgtacc gggcttcctg ccgggcgtgg accaggagca caacggcatc atccggcgcg
    13381 gcgccaagct gctgtacgcc tactgcaacg ccaccgtgcc gaggatctcg ctggtgctgc
    13441 gcaaggcgta cggcggcgcc tacatcgtca tggactcccg ctccatcggc gccgacctga
    13501 cgctggcctg gcccaccaac gagatcgcgg tgatgggcgc ggagggcgcc gcgaacgtgg
    13561 tcttccggcg cgagatcaac gccgccgacg accccgaggc cgtacggcag gagcggatcg
    13621 cggagtacaa ggccgagctg atgcacccgt actacgcggc cgagcgcggc ctgatcgacg
    13681 acgtcatcga cccgcgcgag acccggtcgg tgctgatccg ctcgctcgcc atgctgcgcg
    13741 ccaagcacgc cgacctgccg tcccgcaagc acggcaaccc cccgcagtag gcagcgccag
    13801 gaaagggaga cccgacaccg tgaccccctc gctcgggccg gcggcccggc agtgccagaa
    13861 ggcgctgaac accctccact ccaccgtgta cttcagcccc gacctcggcg gcgaactggc
    13921 cggccgcggt gtcgacgacc cgatggcctg ctatctggcg ggccgggccg cggcactggg
    13981 ccgggtgggg cccggggtgg tcaccgccgt gttccacaac ttccggtacg acatgatcgc
    14041 cggccatctg cccgcgctct gggaccgggt ggcccccgac caggcactgg ccgcccggct
    14101 gcgcgcggcc gacgccaccc tgcgccgggc actgggcgca gaggcgctca ccgcccgccc
    14161 gatgcgggac gcggcccggc tcgccctgcg tgccgtcgag gggtgcggcc gaccgggacg
    14221 cccgctgtac gcggcccacg ccgaccagcc cgtgcccgag gcaccgcatc tggcgctctg
    14281 gcacgtggcg accttgctgc gtgagcatcg cggtgacagt catgtcggcg cgttgagcgc
    14341 ggcgggcctg gacgggatcg aggcgctggt ctcgcactgc gcgagcgggg agggcatgtc
    14401 ccgcgaggcc gtcatgggcc cgcgcggctg gaccaaggag gactgggacg ccgccgagga
    14461 acggctgcgc gagcgcgggc tcatggccgc ggacgggacg ctgaccccgc gcggtgtccg
    14521 gctccggcag gacctggagg aggagaccga ccgccgggac ctcgatccgt accggcacct
    14581 gggcgaggcg ggggtcgccg aactcaccga cctcgccgag gaattcgtcc ggaacgtggt
    14641 cgcgtccgga ctgttcccac cggatgtcga ggccttcttc ctcccaccga accgtgggcc
    14701 gcacacgacc cctcacacat gaccccgcac acgactccgt ctgcggattt gacacagacg
    14761 tgacagagcc gcagacgcat ttgatacggg acttcttgaa cccgatcgcg gcgcggaaga
    14821 ggctgaaatg gcatccgaat cggaaaggca gtggacatgg ccgacggtgc tccggagcac
    14881 tcgtacagca cgggatcgct gacccgggga acattctccc agcttgacca actgcggttg
    14941 ttcgagagca aatacgaccc ggtgacccgc gccgtcatcg agtcgctcga cgtacggccg
    15001 acctggcgct gtctggagct gggcgccggc gccggttcga tgtcgtactg gctggcgggg
    15061 caggtgcccg agggcggcgt gctcgcggtg gacatcgacg acagcaggct ggacgccgac
    15121 caggcacctc aactgaccgt ccggcaggca gacatcaccg ccacggagtt cgaggagggt
    15181 ggctacgacc tggtgctcgc ccgggccgtg ctcgaacacc tcaaggaccc cgacgaactg
    15241 ctgacccgcg cggcacgctg gctggcgccg ggcggctggc tcgtcgtgga ggacttctac
    15301 tacctgcccg ccgagcacgc cgcgaccgcc gtgggacgca ccctcgtcgc cggatatgtg
    15361 cggcgcatgc gcgaacaggg cgcggacctg ggatgggcac ggcacctgcc ggcctcgctg
    15421 gcccgggccg ggctggagtc ggtcggactg cggctcaccc ccgccggtcc cggccagacc
    15481 cccgccgacg acgagctgat cggcctgcgg ctgaggcagg agggccatgc gctggtcgac
    15541 gccggtgtgg tcaccgagga cgaactcgcc gagttcatgg gcctgctcgg ccgcccggag
    15601 ggccgggaca tgacgacgct gatggtctcg gcatgggcac gccgcccggc cgagtgaatg
    15661 ccggccacca cccttaccgt cccttaccgc acgggggagc acccatgccc gaacagcccg
    15721 tacagcccga acagcccgta cagcccgaac cgtccgtaca gcccgagcag cccgtcgtcc
    15781 tgatcaccgc cgcgaccgga aacgtaggcc cgcacgcggc ggcccatctc ctccaggccg
    15841 gtgcccgggt ccgcgcgctg gtcctcccgg acgaccccaa tatcggccgg ctgcccgagg
    15901 gggtcgagat ccaccgcggc gatctcggcg acccggacac cctcgacgcc gccctggacg
    15961 gggtcgacgg cgtcttcctg atgtggccgt tcttctccct ccccgtcgac tccgcgccca
    16021 cggtgctgcg gaagatcgag gccacggccc gccgggtcgc cttcgtctcg tccgtcggcg
    16081 tgcacatcgg cctggagccc gtcgacaaca actgccacgc ctacatcgag aagctgctgg
    16141 agggcacgac gctggagtgg accttcctgc gcaccaccgg cttccactgc aactccgcca
    16201 tgaccttcgc cgaccaggtc cgcaccggcg acatcgtgcg cttcccgtac ggcgccgcca
    16261 cccgcacctc cgtccacgag ggggacctcg ccgcggtcgg ggcgaaggcg ctcaccgccg
    16321 agggccacgc ccgcaaggcg tacctcgtct ccggccccca ggcactgtcc caggcggcgc
    16381 agttgcaggt catcgccgag gtcaccgggc gcgagctgac ctgggaggac atcgagcacg
    16441 acgccgcccg caaggccatg gtcgacgccg gctggccgcc ctcgtacgcc gacggtgcgc
    16501 tcgactactt cgagacgctg accaggacgc cggaggtcgg ctcgaacgtc gtggaagagg
    16561 tcaccggcag gccggcccgc accttccgcg actgggtcgt cgagcacacc cacctcttcc
    16621 actgaccccc gttcacggag gaccacggag ctttcgatga cccgagcgcc cgagcccggc
    16681 ttcaccacct tcgacaccct gacgacccaa tcgcccgacg cggcccgcga gttggccgag
    16741 gccctcatca ccgaggccgc cacacgactg cgccacagcc cgggattcct ctcctcccgc
    16801 gtccacgtcg gcgacgaccg ccgtacggtg atccaccgcg gcctctggcg ggacgccgcc
    16861 gaccaccacg ccgccgccga ccgcctcaag gaactcgcgg accggcccgg ggtacagacg
    16921 gcgaagacct tcgccggcac ccccgccccc ggactgcacg gcccacggac cggcgtgctg
    16981 ccgggccgcg tggccgtggc cacccgccat ctgcgcgacc ccgagtccta cccggccctc
    17041 atggacctgc tgaaccgcag cggtgactgg aagcgccacc accgcggctt catcacggcc
    17101 accccgcaca tcagcccgga ccagctgacc ttcgtcaact acgcgacctg ggaggacgag
    17161 gactcctacc gcgcgtggat ggccgatccg cggatctccg aggggcagga ggagatcgcc
    17221 cggctggagg ccgcgcccgc cgagtacgtg ctctgcgcgg tggtcgccga catccgagcc
    17281 gcgtagtccc gcaccaccgg acccgcacca ccggaccggt acgacccgac ccgaccaccg
    17341 gacccgtgcc accggacccg caccacccgc cccgtacacc tgagaacccg aaggaccgca
    17401 gacaccatga ccgccgtcgg cagcaagccc ctgcgggtcg agatcgcgct cgacctcacc
    17461 tgtgtccact cctacctcgg cttcaaccgc ttccagcggg tcgccgcccg gcaccgggcg
    17521 gcgggcggtg gactcgacgt ggtgttcctg cccttccagg tgtcgcccga ggcaccgccg
    17581 gagggccgcc cgctgtccga ggtgcacctc gccttcttcg gcagcgccga gcaggccgcc
    17641 cgggccaccg cgggcatggc cgccgtcggc gcccaggacg gcctggagct gaacttcgag
    17701 cgggccgtgc atgtgaacac cttcgaggcc caccgcctcc tcgccaccgc ggcccaccag
    17761 ggcctgggcg aaccgatggc cgagcgcctg ttccgggcct acctgaccga agggctgaac
    17821 atcggcgacc gcgccgtact ggaccgcctc gccgccgaga ccggcgtacg gccgaccccg
    17881 gacggagccg aggaactgcg ggccgaactc acccgggtgc gggctctcgg catcagctcc
    17941 gtaccgcagt tccgcttcac cgacacgatc ctcctggccg gcgcccagcc cgaggaggcc
    18001 ctgcagcggg ccttcgaggc agccgcggcc ggcaactgaa atcagcgcct cccccctttc
    18061 ctccccaccc tggagaaccc atgagatcag gacgtacccg ccgcaccctc gccaccgcgg
    18121 gcgtgctgct ggccctcagc ctcacgacgg ggctgagcgg cgccgccgtc gcagagcccc
    18181 tggccaccgc ccgccccgcc gcggtggaag aggcggctcc gcagaccctg gagctcaagt
    18241 cctcgaccga cggactgacg gcgccgacca ccgcgcaccc cggcccgacc acgttccggg
    18301 tgtccaccac cgacccggcg tcgggctgga tatcgctggt ccgtcccaag cccggcgtga
    18361 ccttcgagag tttccgcgcc tccatcctga agatgatcaa cgccgtgggg cccgacatcg
    18421 tcgagggcag tgccgagatg cggcagaagg cggagctgct cggcggcacg gtgatccacc
    18481 cgaacctccc ggcctccttc accaggaccc tcaccccggg cacgtactgg ttcttcgact
    18541 accggaacat ccgggccgag aacccccgtc acagcgtcct cacggtcggc ggcaccaccg
    18601 gcaccggcac cgcaccggcc cccgccgcca cgctcaccgg ccggatgacg gacggtcagc
    18661 cgcgctggaa cctcgacggc accgtgcgcg cgggccgccc gatcctgttc cgcaacgcca
    18721 tgcccgacgg ccagtacatc gaggccatct tcttccgcct cgccgccgac gtcaccgagc
    18781 aggacgtccg ggactacgtc gccgacttcg gcgacaccgg ccagttcccg gactaccccg
    18841 ggcccctgga cctggagcag ggcaccggcg gactgcccat ggactccgga cagagctcgc
    18901 tgctcgaact gacgctccag ccgggccgct atgtcgtggt cgatttcttc agcgacgcca
    18961 aggacggcag cagcctcatc aagcgcggcc attggaagat cttcgaagtc aagtgatccc
    19021 gcgcatcacg acggaggcca cgcccatgaa cctgcgcatc gactacggca cccccgacgc
    19081 cgacgaactg gccgcgctca ccgcggtcct gctggccctg tccgaggcgc cggcgcacga
    19141 caccgacacg gacgggcgcc ctcacatcgc ccgctggcgg cgcccggagc gcatgtccgg
    19201 ccaccgcacc ccacgcagct ggcggagcgc caccgtacgc accagcggat gggcggcgtg
    19261 accgagcggc gggcgcccga ggtccgggac atcaccctcg acgccgacgg cgtcgaggtc
    19321 tcgggcctgg tcgccgtccc gccctccggg ccgtcgcggg ccgtggtggt cgccgtgcac
    19381 ggcggcggca tgcgggccgg ctacttcgac agccggtccc gccccgggct gtccctgctg
    19441 acgctgggcg ccgaactcgg ctgcaccgtg ctggccctgg accgccccgg ctacggactg
    19501 tccgccgccc gtctccccga gggccagacg gtcgaggaac aggcggccgg cctgcacgca
    19561 gccctggccg acttcgcgac ccgccacgac accggtgcgg gcttcttcgt ggtggcccac
    19621 tcctacggcg gcaagatcgc cctcgccacc gcggcgcggg agggcggcga caccctcatc
    19681 ggcctggaca tctccggcct gggcagccgg ttcgcggtcg ccccgcacca gttgcccggc
    19741 gccgagggcg gcggtgactg gcgccggcac tggggtgccc tgcggctcta tccgccggac
    19801 gccttcctgc tcggccgggc gctggtcgcc ccggtgccgg ccagggaggc cgaggagggg
    19861 ccgcgatggc ccgaacggta tgccgggttc gccgcccggg tacgggtgcc ggtccggttc
    19921 accttcgccg agcaggagcg gtggtggcgg tgcgacgacg aggcgctggc cgcgctacgg
    19981 agcccgctgg ccgcgccccg agtggtgatc gaccatcagc cggacgccgg gcacaacatc
    20041 agcctcggct gggcggcccg tacgtatcac ctgcgggcgc tggccttcct ggaggagtgc
    20101 ctgctggcgc gggacgtgat gttcccggcg gcgacggagg agcgcgatgc cgcgctgcgc
    20161 tgagagccgg acgacaaacg gggagacgag agtggacgag aacccggatc accaggacca
    20221 gcgcggcgag cagcgcaccc accccccgag gccggcgttc ctcgccggtg aggacgggga
    20281 gcggcccgac ccccacatct tccgcggaac ggactgagcc ggcctgatga gggccaccct
    20341 cgccgccgcg ttccagtccc tgacgatccg taacttccgg ctgttcgcgg cgggccagat
    20401 cgtctcggtc ggcggtacct ggatgatggt cgtggcccag gactggctcg tcctgtccct
    20461 gaccggggac tcggcctcgg ccctgggcat gatcaccgcc ttgcagttcg cgccactgtt
    20521 gctgttcacc ctgcacgccg ggggcctcgc cgaccgctac gacaagcgcc ggctgctgct
    20581 ggccgcgaac ctcgcctccg ccctgctggc cctgctgctg ggcgcactgg tactggccgg
    20641 agcggcgcgg ctgtggcacg tcgccctgtt cgcgctgggg ctcggcctgg tcaacgccgt
    20701 agaggtgccg gcgcggatgt cgttcgtcag cgaactcgtc ggcgccgatc tgctgcccaa
    20761 cgcgtccgcg ttgagcgccg cctacttcaa ctccgcccgg gtgctgggcc cggcggtggc
    20821 cggcctgctg atcggctggt gcggcaccgg cccggtgatg ctgctgaacg cggcgaccta
    20881 cctggcgacg atcaccgcac tgtgcctgat gcgccccgcc gaactgcacc gcagcgccca
    20941 ccgcccgccc cgcgccccgg tcaccgacgg catccggcat gtcatgaccc gcccggacct
    21001 gctcctgccg atagccctgg ccgcggtggt gggcatgtgg ggcttcaact tccagctcac
    21061 cctccccctg ctggccaaga cggtcttcca cgcggacgcc accgccttcg gcctgctgac
    21121 cacgtccctg gcggccggct ccctcctcgc cgccttcgtc acgacactcc gccggggcag
    21181 acccccactg cgccgcgtca tcgcgacagc cgccggattc ggcgcactgg aactcctgtc
    21241 gggcctggca ccgaccttca ccacggccgc catcctgctc ttcctcaccg gcttcgcctc
    21301 ggtgaccttc gcccagtcca ccaaccaccg catccaactg ggcgcggacc ccgcctaccg
    21361 gggccgggta ctggccctct acaccctcgt cttccagggc acgaccccgc tcggggccct
    21421 cctcctgggc gcgctgaccg aatccctggg agcccgagcc ggcctcctgg caggcggcgc
    21481 ggtcacatta ctggcggcag cgatcgccca cacgatccac cgcacctcag caaaggcacc
    21541 ggccccgaca ccccacccac ccctggaccg gaagccgtcc tagacacgcc ggaacccccg
    21601 gccgaagccg ggggttccag tggggcaagg ccagatcaga cgttgacgcc gaagtcctgg
    21661 gcgatgccca cgagacccga ggcgtagccc tgaccgacag cgcggaactt ccactccgcg
    21721 ccattgcggt acagctcgcc gaagaccatg gcggtctcgg tggccgcgtc ctccgagagg
    21781 tcgtagcggg cgatctcggc gccgccggcc tggttgataa tgcggatgta cgcgttccgc
    21841 acctggccga agttctgcga gcggttctcc gcgtcgtaga tcgagaccgg gaagacgatc
    21901 ttgtcgacgt cggccgggag gccggcgagg ttcactttga tcgcctcgtc gtcgcccgcg
    21961 ccctcgccgg tgcggttgtc accggtgtgg acgatggtct ggtccggcgt ctgcttgttg
    22021 ttgaagaaga cgaagtgacc gtccgagtag accttgcccg tggggttgac cgcgatcgcc
    22081 gaggcgtcga ggtcgaagtc cgtgccggtg gtggtgcgga cgtcccagcc gaggcccacg
    22141 gtgacggcgg tcaggcccgg agcctccttg gtgagcgaga cgttgccacc cttggacagg
    22201 cttacagcca ttgtttggga gtcccttccc tcgttgcggt acggctagaa gctacagcta
    22261 cccctatgaa cgcagacagg ggtacctcaa gttccaggtg tctttacttt ctttgccaaa
    22321 gagcacccgt aggggatatt cacgtgacgt ggaccggaca gtcgcgcgac catgtacgac
    22381 atgtctggtc cctacgtcat ccgcggctcc gtctccctcc ccgaggccga gctcatgtgg
    22441 cgtttctccc gatcgagcgg cccgggcggc cagcacgtca acaccagtga ctccaaggtg
    22501 gagctgagct tcgacctcgc gaaaacggag tcactgcccg aggtctggaa ggcacgagca
    22561 ctccagcgcc tctccacccg actcaccgac ggcgtcctca cggtccggtc ctcggaccac
    22621 cgctcccagt ggcgcaaccg cgaaacagca gccgtacgcc tggcagccct cctggccgag
    22681 gcaacggccc caccccccaa gccccgcaag cccacccgca tcccccgagg catcaacgaa
    22741 cgccgcctga gggaaaagaa gcagcgagca caaaccaagc ggggccgaac gggcaaggac
    22801 tggtaggcac gcaccggcac ccgcgtatgc cgtctgcggg tgcgtggggg ctggtcgcgc
    22861 agttccccgc gcccctgggg cgttgcagtc cccgacccac cccacaaccg tcggcgctac
    22921 gtgaaccccc accgaacccg cgcgggccgc cgcaggcgca cgacgtcaca cccgcacctc
    22981 gaaatccgtc atcccactga cgacggacca cgacgagagg cggcggccac cccatgccca
    23041 ccgacgacga caccgactac ctggcccacc gcttcgaggc ccaccgatcc cacctccgag
    23101 ccgtggcgca ccgcatgctc ggctcgacca ccgaagcaga ggacgcggtc caggaaacct
    23161 ggttccgagt cagccgcacc gacaccagca cggtcgacaa cctcgccggc tggctcacca
    23221 ccgtcacggg ccgggtctgc ctggacatgc tccgctcccg aaagtcccgc gcggaacaac
    23281 ccctcgacac aacgtcaccc cctccgaccc ccaccgcccc caccgacccc gaacaggacg
    23341 ccctcctcgc cgactccata ggcgtagccc tactcgtcgt actcgacacc ctcacccccg
    23401 ccgaacgcct cgccttcgtc ctgcacgacc tgttcgccgt gccgttcgag gagatagcga
    23461 ccgtcctcga ccgcaccccc gccgccgccc gccagctggc cagccgcgcc cgacgccgag
    23521 tgcagggcgc agagccgccc gagcacgacc ggacctgcac ccacaggcag cgccaggtcg
    23581 tcgaggcctt cctggccgca gcacgggagg gcgacttcga gggcctgctg gacgtcctgg
    23641 acccggacgt cgtcgcccgc accgaggccg gcgtgacgac cggcgccgcg gcggtggcac
    23701 ggggcgcgtc gacgttcggt tcggcggcgc tcgccgcgag gcccgccctg accgtccgcc
    23761 acgccctgat cgacggcacg acggcggtcg tggccctggc cgacggccga ctggaacgcg
    23821 ccctgaagtt tgcgttcgta cgggatcgaa tcaccgtgat cgacatcgtg acggcccccg
    23881 accgcctggc ccgcctcgac atcgacctga tctagcgccc gcccggcccg gaccgcgtgt
    23941 ccgatcgccc cacccgcccg agatccagca cgcccaccac ctcgtcctcc gccgtctccc
    24001 cggtgtcccg gaacccgagc ccgccgtaga acccctccgg cccgccgggc ccgggatgcc
    24061 aggtgacgta cagaagatcc ccaccccggc ggcggatctc cgcgcccacg gactccacgg
    24121 cgaaccgccc gtacccccgc ccctgttccc gcgcgtcgat gttcagccgc cagagcccgg
    24181 agcgccgcac gctcccgtcg ccgtgccagt cgatgtcgaa gaaggccatc aggaacccga
    24241 cggcacggtc gccgtcgacg atgagccggg gccaggcgac ccccggagga tgcacatacg
    24301 cctcggcgag ggactgcatc acgggggagg acacgcgttc ctgatcgggc cggacccgta
    24361 tcccggtcgc ggtatcgaaa ttcgcaggtg tgatgatttc aagacgaaga tcagaagtgg
    24421 tcgaagtcac cccggaacgg taagccggaa gatcactcaa gggccaagga attacgcccg
    24481 cccaccgctc cgcacggaaa tcagcccaac tgccggtagc gcccccggaa atacgtcagc
    24541 ggccccccgt ccgcactcgg cagcgaggcc gacagaacac gcccgatcac cagcgtgtgg
    24601 tcaccggcgg gcacccgctg ctcggtccgg cactccagcg tcgcgagcgc gcccccgacc
    24661 agcggggccc cgctctcggt gccacggacg tacggaatgt cggcgaacag cagccgatca
    24721 ctgacccgcc ccttcatcgc gaaccgcccg gcgatgtgcc gctggctctc cgtgagcacc
    24781 gacaccgccc acagcggctg ctcggcgagc aggtcgtcca tgcgggagcc ctcacgcagg
    24841 ctgaccagca ccaacggcgg atccagggac accgacatga acgccgtggc tgtcatgccg
    24901 acgtcctcac cggccggggc gtgcgggtcg tccgggtcca ggggcggctc cagcgcggtc
    24961 accaggacca cacccgcggc gagccgcgac atggcggctc gaaactcgtc gttgctcact
    25021 ccctcagcat ggaggaggga ggtcgagggc tgcgcggcag gggaagtgtt cggcacgccg
    25081 aaaacgctaa tgtcgcttcc ctgcacctca catcgggcct gcgcccgaga acggacctag
    25141 gactcccgac ggacaaccgg cggagtccgg tcgcaccggg gtcacagttg tgcggaactt
    25201 gggttcagta aacgcacagg aaaaacgcag aaactccgct caattgttca cgtttagctg
    25261 tgacttgagt cacaagagcc attaattgtt gaccctgtgt accgagtggg cagcgcgctg
    25321 tgattcagtg gcggggaact ggcaagggaa gttacgccga agtagaaccc ttgattcgct
    25381 gcgaggtctc ggggggaggg cgagcatgga gaccgagtcg gagccgtacg tccgtcttgc
    25441 gaccctgcgg caacttcacc aggtcatggc tgacatgaac acggcccgta gcctggcgga
    25501 cacacttcag accgtcgccg acggcgtcgt caccggcctc ggctatgaac tcgcgtgcgt
    25561 caacctcgta cgccccgacg gcgacctcgt cgtcgccgcc ttcgccggca atcccgcagc
    25621 cgaggccctc atcaccggcc gtgtcggctc gcgcgattcc tgggagcgcc ggctgaacat
    25681 gggcgagcac tggggcgacc tggtcttcat cccgcacacc gagggctgga tcctcgacga
    25741 cgacgacgta ccgcagtggt acaccgacgg ccccgcgccc cgtttcgagg acgagtggca
    25801 cccgagcgac cggctcttcg cgccgatgta cacgcccggt gtgcagggcg gggcgtgcgg
    25861 tgagctgatc ggcgtcctgt ccgtggaccg gccgcgcaac ggccggctgc cgggcgcatg
    25921 gggccgcgag gccctgcaga tgtacgcgtt ccaggcggcc atcgccatca gcaacgcacg
    25981 tctacgcgcg aatatgcagc gggcattggt caggctggag cgcgaccagc aggccctgcg
    26041 cgccagcgag gaaagcttca ggcaggcctt cgagtacgcc ccctccggca tggccatcgc
    26101 cgagatgggc ggcgaccagc acggccgcat cctgcgcacc aacgacgcgc tctgccgcct
    26161 cctcggccgc cccgcctccg cgatgcgccg ctactccttc tccgacctgg tccaccccga
    26221 ggacatcggc accctgctgc ggacctcggc ggagggcggc cgcgcggaac tccgcctcgg
    26281 ccggcgcgac ggcacctacg tctgggtctc cctgcgcaac tccgtcgtcg ccgacgccgc
    26341 cgacggcccc cgcttcctcc tcacccacgt cgaggacatc gaggagcgca agcgccgcga
    26401 gctccagctc gcccaccgcg cctcccacga ctcgctcacc ggcctgccga actccgccga
    26461 gctgcgcgcc cgcctgtccg cccggctctg caggcgcgcc gcccacgcgg gcgccctgga
    26521 gtccatggac gccgcctacg gccacccggc cgtcttcgac gccaacggac acggcttcga
    26581 cttcccgggc gcggccgcgc tggaggcctt cgaccaccat gtccacaccg tctccccgga
    26641 cgagggcgag cgcgacgacg gcaccaaggg gctcgcggtc ctcttctgcg acctcgacgg
    26701 cttcaagtcg atcaacgacc ggttcgggca caacgcgggt gacgcggttc tcatcgaggt
    26761 cgcccggcgc ctgacccgcc aggtacgcga cggcgacacc gtcgcccggc tcggcggcga
    26821 cgagttcgtg atcctcgccg acggactcgg ccgcgccgac gccgccgacc tcgccgtacg
    26881 cctgcgcaac gagatcatcc agccgatccg cgccgagggc cgcgccgtac gggtcggggc
    26941 gagcttcggc atcgggtggg cacactgcgg gatgaccgcg gacgaagtgt tgaagtccgc
    27001 tgacgagcgg atgtacgtag agaaacgatc tcgtcccaaa cagcacagac gcgcgggatg
    27061 atccccaggt cagcgagctg atgcgatccg agtcacccgt ttgggccatc aggagcgggt
    27121 aggctcgcca ttctgacccc acgtatcgca tctgcccgca cctggtgagg agacccaagg
    27181 gatgacgtcc ggcaacaacg gggcgagcac gcccgaggac gacgacccgt tcggctacct
    27241 ctacgccgat ggtcaggcca atggcgccca gccgccctcc ggcggcgggg gctacggcta
    27301 cccgggctcg gtcaaccgtg tacgcgcggt cggacagcgc cagtacggcc agcaggcccc
    27361 ggccccgcag atcccccagc aacagggcac ctacggccag ccgaacgccc actacgccgc
    27421 cccggaaacc ctccccggcg gcgcccccac gacggcccag ccggcgtaca gcggcggctc
    27481 ggggtcgggc cgcggtggcg gccccaacac caagggcctg ctgatcggcg cgatcgcggt
    27541 cgtggcggcg gtcgtcatcg ggatcagcgt ggcgatgctg ggcggggacg acgacaaggg
    27601 caacgaggcc gacggttccg gctcgacgcc gacgcagagc cagagcgccg agtccagccc
    27661 gtcggcgagc agcagtgcgg aggaacaggc cgagctgccg aagatcgacg cgaaggcgct
    27721 gcgcttggag ggcggcgcca ccacggcgtc ggagttcaag ggcgccaagg cggagggcgg
    27781 cgtctatgtg accggtttca accaggtcgg agccaaggtc acctggaccg tcaacggcat
    27841 cgagaaggcc ggcacatacc ggctgtacgt gcactacggc gtcccgggga aggacgccga
    27901 cgcgacgctg gtggtcaacg gcacggccca gtcacgggtc ctgaacatgg agaacttcgg
    27961 caacaccccc gagggcgact gggaaaaggg ctggaaagac acgtggtcca acgtgaacct
    28021 gaacaagggc acgaacacga tcacgcttgc ctgtaacgac ggcaaccagt gcgacgcggt
    28081 ccttgaccag atgtacctca ccggggaaag cggcaactga gcagagtcag gccgcgctga
    28141 cctccccgct caccgccacc cgccccagca actcctcgta cgtcccccgg tcgaactccc
    28201 cggccaccgg cgccaggacg ctcgccgcgc tcagtgctgc cgcgcgggcc agtcggtccg
    28261 gccaggggag cttctccacc aggcccgaca gcaggcccgc gaccgccgcg tcgccggcgc
    28321 ctgtcgggtt gccgtgcagg gaagcgggcg ggacggcccg ccagcggcct tccggggcca
    28381 gggccagcag gcccgacctg ccgagggagg cgaccacggc gcgggcgccc cggcggcggg
    28441 cgtcctgcgt cgcgcgcagc ggctcgtggg agccggtcag ttcggccagt tcgtcggcgt
    28501 tgggcttgat gatgtcgggg cgggcggcga caccccggcg cagtgcctcg ccggccgtgt
    28561 ccagcagcac cggcacctcc gcggccttcg cggcccgtac gagaccggcg tacgccccga
    28621 ccggcacgcc cggcggcagg ctgccgcaca gggccaccgc ggaggcggac gtcagcaggt
    28681 cctcgtatgc ctcctggaag gcggaccact cggcgggtgt gatcgtcggg ccgggctcat
    28741 tgagctgggt cgtgtcgccc gtgtgggcgt cgacgacggc gatcgtgcgg cgggtcgggc
    28801 ccgtcacggg caccagcgcg tccaccacgc cccgcgtccc ggtcagttgc tcctggacca
    28861 ccaggcccgt cgcgccgccc gtgaaccccg tgaccgtcac ctcgtgccct agggccgcca
    28921 gcacgcgggc cacgttcagg cccttgccgc cggggcgttc ggtcacctcg gtgacgcggt
    28981 gggaggtgtg gggtcgtagc gccggtacgc gataggtgat gtcgagagcg gtgttcagcg
    29041 tgaccgtcag aatcacctgg gccgacctcc cccgaagagt tcagaacgcg tgtgccgtcc
    29101 gtccgccgga agttccccgc ggagatcccg atcatgccaa aagggcggcg gccgtcccag
    29161 tctcgcagga caaccaccgc ccccaacagg cggacacatc accccagttg gggatcgacc
    29221 acccattctc cccggcgcat cacgcccttg aggtcgaagg cggagtcgag aatgaccagg
    29281 tcggcgtcct tgccgggctc cagggagccg atgcggtcgt agcggcccag gagcttcgcg
    29341 gggttcgcgg acagggccga cacggcgtgc tccaccggca gccggtccac cgtcaccgcc
    29401 cgcttgaagg cgcggtcgag ggtgagggtc gagcccgcga tcgagccgcc ttcgacgagg
    29461 cgtgccactc cgtcggcgac ctccacctcc aacgggccca gcatgtaacg cccgtcgccg
    29521 aagccggccg cgtccatcgc gtccgtgatg aacgcgaccc ggtccgcgcc cgcgtgatgg
    29581 aacgccagct gaagggcggc cgggtgcagg tgggtgccgt cgttgatcag ctcgaccgtc
    29641 acccgctcgt cctccagcag ggccgcgatc gggcccggct cacggtggcc gaggggcggc
    29701 atcgcgttga agagatgggt ggcgaccgtc gcccccgcct cgatcgccgc caccgtctgc
    29761 tcgtacgtcg cgtccgtgtg cccgatcgcc gcgatgacgc cgtgttcggc gaggaggcgt
    29821 acggagtcga tgccgcccgg cagttcggtg gcgagggtga ccatcgcggc gtggccccgc
    29881 gcggcgtcga tcagcttgcg gacctccgcc gggtcggggt cgcgcagcag ctcctcggag
    29941 tgcgcgccct tgcggcacgg ggagatgaac gggccctcga aatggatgcc cgcgatatcg
    30001 ccctgctcgg ccagctcgga cagcaggccc gcgcgccggg tgaggaagtc catgtcgccg
    30061 gtgacggtgg aggcgacgag ggtggtggtg ccgtgcaggc ggtgggtgtg gatgcctttg
    30121 accacgtcgt ccggcgtgcc tgaagtgaag gaggctcctc ctccaccgtg gttgtggatg
    30181 tccacgaagc cgggcactac gtggtggccg gtgaggtcga tgcggtgggc gttctccggg
    30241 gccgcggcgg cgattcgggt gccgtcgatg atcacctcgc cgtccttgac ggttcccgtc
    30301 ggcgtgacga cgttggcgcc ggacaggatg agggggatct tgtccgtcgc ggggtgcggg
    30361 tgcgttgtgg ctggtcgcgc cccgcggcgg agccgcatat tggcgctgtc ccgcgcccct
    30421 gggtgggctg tcatcaggcc gattcctccg tacggtcggt ttggtcgagg agatcccagg
    30481 ccaggaggcc ggcacccagg catccggcgg tgtcgccgag ggccgcgggg acgatggacg
    30541 gcaacttctg gaaagtcacc cggctccgga ccgcgtcccg cagtggtgtg aacaaggttt
    30601 cccccgcctc ggccaggccg ccaccgatga tcagggtgcg ggggtccagc agggtgaggg
    30661 cggtgaccag gccgtcggcg agggcgtcga cggcgttctg ccatacccgt acggcgttcg
    30721 ggtcgccgga cgtgacggcc ttggcgcagt ccgcggcgtc cacctcgggg tccccgaccg
    30781 cggcggccca cgcctcgctc accgccgccg ccgacgcgaa ccgctccaga cagccgtgct
    30841 gcccgcacgg gcagggggcg ccgccgggcc gtacgacgat gtggccgatc tcgcccgcga
    30901 agccgtgcgc gcccgactcc acccggccgt cgaccccgat cgcgcccgcg atgccggtgc
    30961 cgagggccac gaagaggtac cggtcggcgc cccggcccgc tccgatgcgg ccttcggcca
    31021 gccctccggt gcggacgtcg tggccgaggg cgacggggat gccgccgagc cgttcggaca
    31081 gcagccggcg caggggtacg tcgcgccagc cgaggttggc cgcgtaggcg gcgatgcccc
    31141 gctgctcgtc gacgatgccg gggacggcga cgccggcggc gaccgcgggc tcgccgaagc
    31201 gctcttcgcc gtacgcgcgc agttcggcgg cgaagtcgag gatgccgtcg atgaccgcgt
    31261 cgggcccgcg ctcgcgcccg gtcgggcggc gggcttgatg gagcagctcg ccgctcgtcc
    31321 ccgcgagcgc ggctttcatc ccggttccgc ccacatcgag ggcgatgacg tgtctcacgg
    31381 gggacagtgt cccttgcgca cccgcgagag gtctagtcca cttacgtggt gtagacctta
    31441 gggggcaata tgtatgacgt ttcgaaattt tcgaacttgg gtgtggggcg gtaccgcgtg
    31501 cagcggcgta gtcgtattcg tgatcgtggt cgtacgggag tggtcgcggc cgtgtccgcg
    31561 ctggggctga cggcggccct gggcggctgc gggctgaccg gagactccgg cggggtgacg
    31621 ctgagactgg tcgccgcgga ctacggggac agcgagtcga acagctccca gaagtactgg
    31681 gacaagctcg tcgaggccta cgaggccgag caccccggcg tcacggtcga cgtcaccgtc
    31741 tactcctgga gcgacgtcga cgccaaggtc aaggagatgg tcgacgccgg gaaggcgccg
    31801 gacatggcgc agatcggcgc gtacgccgac tacgccgcga agggcctcct ctacgaggcc
    31861 gacgaactgc tctcgatccc cgtccaggcc gacttcgtcg cgcagttcgc ggacgcgggg
    31921 caggtgaagt cggtgcagta cggcatcccc ttcgcgtcct ccacccgcct gctcttctac
    31981 aacaagaccc tcttccagaa ggccggactc gacgcgccga agacctggaa ggaactggcc
    32041 gccgacgccg aggccctcaa ggcgcagggc gtgaagtacc cgtacgccct gccgctcggg
    32101 cccgaggagg cgcaggccga gacgatgcag tggctgctca gcggcggggg cggctacacc
    32161 gacaacgcct ccggcaccta cagcatcgac tccgcggaga acgtcgccac cttcaactgg
    32221 ctcaagaacg acctggtcgg caaggggctg acggggccgg tggcgccggg gaagctgaac
    32281 cgggcggccg cgttctccgc gttcgcggac ggtgacgtcg gcatgctcaa cggccacccg
    32341 tccctgatgc agacggccgc gaagaagggc gtcaagttcg gcatggtgcc gatgcccggc
    32401 gtcgacgggc cgagcaaggt ctccatgggc gtcgcggact ggatgatggc cttcaaggag
    32461 aacggccacg cggacgaggt cggcgacttc ctcgacttcg tctacgacaa gcagaacgtc
    32521 ctcgacttct cccgcgagta caacctgctc cccgtcacga actccgcgtc cacggtgatg
    32581 accgcggccg acgaggacgc cgacctcaag cccttcctcg aggaactccc cctctccgag
    32641 ctctacccgg tcggccggac gtcctgggcg gcgatcagcg cggacgtcaa gaagcggatc
    32701 ggcggcacgg tggcggcggg tggcagcccg tcggcgatcc tggggcagtt gcagctggcg
    32761 gcgacgcggg cggagagcgc ggagtagccg ccgctgtcag tggcgggggt tacggtgcga
    32821 cccatggacc aggacccgac gaagcccgcc ctcgcggacc gcgagcgggc catcctcgcg
    32881 ctggaacgcc ggggcttcac cggccccggc gcgaaggagc gcgcgatacg ggaggaactg
    32941 ggcctggccc ccgtccgcta ctaccagctc ctgaacgccc tgctggatga tccgcgggcg
    33001 ctggaacatg atccggtgac ggtgaatcgg ttgcggaggg tgcgggaggt tcggcggggg
    33061 gagcggtgag ttttcttcgc ccccgccgcc cctacccgtc ccgccctggg gctccgcccc
    33121 agaccccgct cctcaaacgc cggaggggct gactacccag cagtccccgg ggacgggacg
    33181 cgtaggggcg gcgggggcga aaaaatcagc gccccgccag ccgcgcgtgc gagcgcaccc
    33241 cgctggataa ggtcccccca tggacagcca caaggatctg cccaccccca ccacccaacc
    33301 cggccgggac ggactcgccg ctctcctggc ccgtccctcc cgcgccctca tcgccctcga
    33361 cttcgacggc acgctcgccc cgatcgtccc ggacccggag caggccaggg cccaccccga
    33421 cgccctcccc gccctggcag ccctcgcgcc gaaggtcgcc gccgtcgccg tggtcaccgg
    33481 gcggcccgcc gacgtcgccg tgcggtacgg cggtttcggt ggggttccgg ggctggagca
    33541 tctcgtcgtg ctggggcact acggtgccga gcgctgggac gccgtgagcg gaaaggtcac
    33601 cgcaccggac ccccaccccg gtatcgccgc cgtccgtgcc gagctgcccg cgctgctgga
    33661 gggccacggc acctggatcg aggacaaggg acacgccgtg gccgtgcaca cgcgccgcgc
    33721 ggccgatccg cagggcacgt tcgacgccct gcgcgccccc ctcaccgatc tcgccacccg
    33781 caacggcctg atcgtcgaac cgggacggat ggtgctggaa ctgcgtcctc cgggcatgga
    33841 caagggggtc gcgctgagcc ggtacgtgcg cgagctcggt gtcgagtccg tcctctacgc
    33901 cggcgacgac ctcggcgacc tccccgccta cgcggccgtg gaggcgctgc gttccgacgg
    33961 caccttcggc gtcctggtgt gcagcggcag cgaggaggtc accgagctgt cgcagcgggc
    34021 ggatgtcgtg gtcgacgggc cggaaggggt cgtacggctg ttgcgggcga tcgctgatca
    34081 ggtggaccga ggccccggcc ccggctccga cccctcctcc agcgcgcgca actgatccag
    34141 gaaccactgc gccggcggca acgccgttgc cgccgcggcc agcctcttcg agcgttccgc
    34201 ccgttcctcc ggccgcatcg tcaacgcctc gtgcagcgcc cgcgccgtgt cgatcacgtc
    34261 gtaggggttg acggggatcg cgtcctcgcc cagttcctcg aaggcgccgg cctcccggga
    34321 gagcaccagc gcgcacccct cgtcggagag gacgggcatc tccttcgcga cgaggttcat
    34381 gccgtcgcga atggggttga ccagcgccac gtcggcgagt cggtaggcgg ccagggagcg
    34441 ggcgaagtcg tccttgacgt ggaggacgac cggggtccag tccggtgttc cgtagcggga
    34501 gttgatctcc gtcgccaggc gctggacctc cgccgtgtag tcgcggtaga ccgccaggtc
    34561 ctggcgggag gggtacgcga aggccacgtg cacgaccttc tcccgccact cggggtggtc
    34621 gtcgagcagt tggccgtacg ccagcaggcc gcgcgcgatg ttcttcgaca gctcggtgcg
    34681 gtcgacccgg acgatcgtct tccggccctc gccgatctcg tcgcgcagcg cctccatccg
    34741 ctcggccaca tcggcctgat gcgcccgcgc ccgcaggaag tccgcgtccg cccccagccc
    34801 gtgcaccccg acccgcgtgc ccccgagccc gccggcgaac cgctccgcgc acgcctcgaa
    34861 cgcgtccgcc caccggcggg tcaggaagcc gagccggtcc gcgccgagca tgccgcggag
    34921 gagctgggtg cggatgtcgt ccggcagcat cccgaagtag tcggccggcg cccacggcgt
    34981 gtgcgagaag tggccgatgc ggaggtcggg gcgcaggtcg cggagcatcc cgggcaccag
    35041 gcacaggtgg tagtcctgca ccagcaccgc cgccccgggc gccgcctccg cggccagcgc
    35101 ctgggcgaag gcgcggttgt acgtctcgta cgccgcccac tgccgccgga actccgcgtc
    35161 gaagaccggc tccagcggcg tctggtacag catgtgatgg acgaaccaca ggaccgagtt
    35221 cgcgatgccg ttgtacgcgt ccgcgtgcac atcggccggg atgggcagca tgcgcacgcc
    35281 ctcctcgccg gccccgcgcc gcaccgcctc ccggtcgccg tcggacagcg ccgagcacac
    35341 ccacagcgcg cccgcgtccg gcccgatcgc cgagagcccg gagacgaccc cgccgccgcc
    35401 ccgcttggag tgcagcgagc cgtcctcgcc caccgagtac gagaccggac cgcggttcga
    35461 agcgaccagc accttggaag ccatacgcca caacctagcc cgcctcggaa acgctcaaac
    35521 gtacgcttcc gctcagtagc cgaagcccgt acgccctgta tacggccggt ttccggcgtt
    35581 tacgcgacct tccgtgtcgc gtactcggcg atctccacca tcggcggccg ttcctcggtg
    35641 tccacagagt acgtacgtgg ctcgaaaccg tccccgcccc gctcgaactg ggtgagggaa
    35701 gggcggacca gatgtccgcg cgccagcctc agctgtgccg tgcggtagat cgccgcggac
    35761 atccggccga gcgcctgtcc gtcctggtgg cggtgcttgc gcaccccgac gtccacctgg
    35821 gccagcgcgt ccaggcccac cagatgcagg gcgtcgacca gcatgcccag ctcgacgccg
    35881 tatcccacgg ggaacggcag ctgctcgagc agcgacctgc gtgccgcgta ctcgccgccc
    35941 agcggctgta cgaaaccggc cagctggggc cagtgcatgt tcagcagcgg gcgggccatc
    36001 agttccgtga cccggccgcc ctgcccggcg gcgccgccga gggggcggtc gtacatcgcc
    36061 ttgaccagat cgactcccgg gtcggtgagc agcgggccga cgatgccgga gacgaactcg
    36121 gaggagaact ccctcaggtc ggcgtcgatg aagcagacga tgtcgccggt cgtcaccagc
    36181 agggagcgcc acaggacctc gcccttgccg ggtacggccg ggatgcgcgg caggatcgcg
    36241 tcgcggtgga cgaccctcgc accggccgcc gcggcgacct ccgaggtgcg gtccgtggag
    36301 ccggagtcga ccacgacgat ctcgtcgacc agcgggatct gccggaccag gtcatggacg
    36361 atgaccgcga cgatgtcgcc gacggtctcc tcctcgtcga gcgcgggcag gacgacggag
    36421 accgactggc ccgtacgctg cttggcggcc aggatctggt ggacggggcg atcggcggcg
    36481 gaccaggagc gggtgctcag ccagcgctcg gcttcttcca gcacggtcgg tggctcctca
    36541 catgtgtctc gcggttcgga cgactatctc aactgtcctg gccttcggtt acagtcttga
    36601 acaacgccga tgaccatcgc atgtccgagg tcaccgagct gacaaccgaa taccgctcat
    36661 ccagaggggc agagggatac ggcccgatga agccccggca accctccagc cggtctttcc
    36721 acgtcgttgt ggtgaggctc ccggctaggg aaggtgccaa atccgtctca cggcgagatg
    36781 cgtcgtgagg aagatgagga gaaagggcct cgcctcacat ggctgcgcag actgttgcaa
    36841 gcaccactga atccaccgta gacctcggcc ccgccgcggc gctctcctgc cgcgagtgcg
    36901 gtcatcgggt accgctcggc ccggtcttcg cgtgcgagga gtgtttcggc ccgctggaga
    36961 tcgcctacga cttctcggcc tacgacgccg aggagctccg caagcggatc gaagcgggtc
    37021 ccgcgaacat ctggcgttac gcgccgctgc tgcccgtccc cgccgacgtg gccaccaagc
    37081 cgaacatcaa ccccggctgg acccagctcg tcaaggccga caacctcgcg cgtgagctgg
    37141 gcgtcgacac cggcaagctg ttcatcaagg acgactccgg caacccgacg cactccttca
    37201 aggaccgcgt cgtcgcccag gccatcgagg ccgcccgcgc cttcggcttc accacgctct
    37261 cctgctcctc caccggcaac ctcgccggtg ccgtcggcgc cgcggcggcc cgcgccggct
    37321 tccgctcctg cgtgttcatc ccgcacgacc tggagcaggg caaggtcgtc atggccgcgg
    37381 tctacggcgg cgagctcgtc ggcatcgagg gcaactacga cgacgtgaac cgtttctgct
    37441 ccgagctgat cggcgacccg gcgggcgagg gctggggctt cgtcaacgtc aatctgcggc
    37501 cctactacgc cgagggctcc aagaccctgg cgtacgagat ctgcgagcag ctcggctggc
    37561 agctccccga ccagctggtc gtgccgatcg cgtccggctc gcagctcacg aagatcgaca
    37621 agggtctgca ggagctgatc aagctcgggc tcgtcgagga caagccgtac aagatcttcg
    37681 gcgcccaggc ggaagggtgc tcgccggtgt cgacggcctt caaggccggc catgacgtgg
    37741 tccggcccca gaagccgaac accatcgcca agtccctcgc catcggcaac ccggccgacg
    37801 ggccgtatgt cctcgacatc gcgcgccgca cgggcgggtt cgtggaggat gtgacggaca
    37861 cacaggtcgt cgaagcgatc aagatcctgg cccgcacgga gggcatcttc gcggagaccg
    37921 ccggtggtgt gacggtgggt gtcgcgaaga agctcatcga gaacggggtc ctcgacccca
    37981 ccaagaccac cgtcgtgctg aacaccggcg acggcctgaa gacgctggac gcggtggccg
    38041 gtaccggtct gaccgccacc atccgcccga acctggactc cttccgagag gctggcctcg
    38101 catgagcgtg accgttcgta tccccaccat cctgcgcacc tacaccggcg gacaggccga
    38161 ggtcgccgcc gagggtgcca acctcggtga ggtcatctcc gacctggaga agaaccacac
    38221 cggcatcgcc gctcgggtgc tcgacgacca gggcaagctg cgtcggttcg tgaatgtgta
    38281 cgtcaatgac gacgacgtgc gtttcgagca ggggctggag acggccacgc ccgacggggc
    38341 cggcgtttcc atcatcccgg ccgtcgccgg aggctgatcg gagctgaccg aatgaccgaa
    38401 cattaccgtc ggtaacaccg gtcaccgaga gttcattgaa ttgccccctc cgtgagagaa
    38461 gcggaggggg caattctgtg tggttgagcg gggtacagtt ggggaatgtg ccgccgatct
    38521 ccgagtcggc tgcccttgat ttctgccgcg ggcccgacaa gaagtagcca aagtgtgcgg
    38581 gttttttgcg gcttctgttc cttttgtcag gtccgacttg acctgaagtc aggggaattg
    38641 tccccacatt cccgaccggt cgtgcccgga tttctcgtcc gattgacctg ttgcagacgg
    38701 cagttgggca gatacattca gccgcggtcg acgcgttccg gcgcacgccc ccgaccgatg
    38761 gggggtgagg tctgacccgg atccgcgaag tgtggatctg tgcaagggcc agtaataggg
    38821 gagttaggca tggctcaggg caccgtcaag tggttcaacg cggagaaggg gtacggcttc
    38881 atcgcggtcg acggtggtgc ggatgttttc gtccactaca gcgcgatcca gatggacggg
    38941 taccgcaccc tggaggaagg ccagcgggtc gatttcgaga tctcgcaggg tcagaagggg
    39001 cctcaggcgg acatggtccg gctggcggcc ggctgaagca cgcgtcgact aacagcagcg
    39061 acgttcttct tcgaagggcc cgcacctccc ggggtgcggg cccttcgccg tgcccggacg
    39121 cgggggttcg atccccgaga gccgcttgcg cccgcccgtc gcccgaccgc cacccctcat
    39181 cgagcgctcg cttcgcgagc gcgccttgca ctctcatggg tcgagtgcta atcattggcg
    39241 ttagcactct gaaggtgaga gtgacaaaga aggaccgggt cggtgaggcc cgcaggccgg
    39301 gtggggcaag gaaccacaag gcatgtgagc cgtccgtcgc gggcgcgggc gcggtccgaa
    39361 ggaatcaccc ccagtcctgg agggaccact tcacatggcc aagatcatcg cgttcgacga
    39421 ggaggcgcgg cgcggcctcg agcgcggcat gaaccagctc gcggacgccg tgaaggtgac
    39481 gctcggcccc aagggtcgca acgtcgtcct cgagaagaag tggggcgccc ccacgatcac
    39541 caacgatggt gtctccatcg ccaaggagat cgagctcgag gacccgtacg agaagatcgg
    39601 cgccgagctg gtcaaggaag tcgccaagaa gacggacgac gtcgccggtg acggtacgac
    39661 caccgcgacc gttctcgccc aggccctggt caaggaaggc ctgcgcaacg tagccgccgg
    39721 cgccaacccg atggccctca agcgcggcat cgagcgtgcc gtcgaggccg tctccgccgc
    39781 cctgctcgag caggccaagg atgtcgagac caaggagcag atcgcctcca cggcctccat
    39841 ctccgccgcc gacacccaga tcggcgagct catcgccgag gccatggaca aggtcggcaa
    39901 ggaaggcgtc atcaccgtcg aggagtccca gaccttcggt ctggagctgg agctcaccga
    39961 gggtatgcgc ttcgacaagg gctacatctc ggcgtacttc gccaccgaca tggagcgtat
    40021 ggaggcgtcg ctcgacgacc cgtacatcct gatcgccaac tccaagatct cctcggtcaa
    40081 ggacctgctc ccgctcctgg agaaggtcat gcagtcgggc aagccgctgc tgatcatcgc
    40141 cgaggacgtc gagggcgagg ccctgtcgac cctggtcgtc aacaagatcc gcggcacctt
    40201 caagtccgtc gcggtcaagg ccccgggctt cggtgaccgc cgcaaggcga tgctgaacga
    40261 catcgccatc ctcaccggcg gcgaggtcat ctccgaggag gtcggtctca agctggagaa
    40321 cacctccctc gacctgctgg gccgcgcccg caaggtggtc atcaccaagg acgagaccac
    40381 catcgtcgac ggcgccggct ccacggagca ggtgcagggt cgcgtgaacc agatccgcgc
    40441 cgagatcgag aacagcgact cggactacga ccgcgagaag ctccaggagc gcctggcgaa
    40501 gctcgcgggc ggcgtggccg tcatcaaggc cggtgccgcg acggaggtcg agctcaagga
    40561 gcgcaagcac cgcatcgagg acgccgttcg caacgcgaag gcggccgtcg aggagggc
//
