LOCUS       NZ_BNBM01000027        56512 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces lanatus strain JCM 4588 sequence27, whole genome
            shotgun sequence.
ACCESSION   NZ_BNBM01000027
VERSION     NZ_BNBM01000027.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces lanatus
  ORGANISM  Streptomyces lanatus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 94173)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 61X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014655715.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 05:46:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,254
            CDSs (total)                      :: 9,172
            Genes (coding)                    :: 8,973
            CDSs (with protein)               :: 8,973
            Genes (RNA)                       :: 82
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 199
            CDSs (without protein)            :: 199
            Pseudo Genes (ambiguous residues) :: 0 of 199
            Pseudo Genes (frameshifted)       :: 83 of 199
            Pseudo Genes (incomplete)         :: 153 of 199
            Pseudo Genes (internal stop)      :: 16 of 199
            Pseudo Genes (multiple problems)  :: 50 of 199
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:57:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2417
            Orig. end                         :: 58929
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BNBM01000027.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..56512
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /candidate_cluster_numbers="4"
                     /contig_edge="False"
                     /product="T1PKS"
                     /product="hglE-KS"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="(hglE or hglD)"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..56512
                     /SMILES="CC(=O)CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="(hglE or hglD)"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="neighbouring"
                     /product="T1PKS"
                     /product="hglE-KS"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /protoclusters="2"
                     /protoclusters="3"
                     /tool="antismash"
     cand_cluster    1..44659
                     /SMILES="CC(=O)CC(=O)C(=O)O"
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..44659
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:24659](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..24659)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     misc_feature    complement(132..141)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.45"
                     /tool="antismash"
     gene            complement(215..1048)
                     /locus_tag="IE325_RS43115"
                     /old_locus_tag="GCM10018780_87380"
     CDS             complement(215..1048)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019545494.1"
                     /locus_tag="IE325_RS43115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87380"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_229912467.1"
                     /transl_table=11
                     /translation="MTEPRRPPELGDIQETLLIPLYARAVETSKRHGMLSDPRAVEMVD
                     AIDYDFTRFDGAKSLLGANLRTLLFDAWVADFLQRHPKGTVVEIGTGLNTRFERLDNGT
                     VHWIDLDLPDVIELRRTFFQDTDRRRMLALSVTDPAWTDEVRKSPGPYFLAAEAVLIYL
                     EEQQVHSVFDLIAERLPGALLALETAAGRMVDSQDSHDVLGKVAARMRWRCDDPTALER
                     WRPGVHLTDSCSFARLPAPVARRLNPAYRLMLRAASLLRRRDMEAYRFNLFRFAD"
     gene            complement(1066..2109)
                     /locus_tag="IE325_RS43120"
                     /old_locus_tag="GCM10018780_87390"
     CDS             complement(1066..2109)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087968.1"
                     /locus_tag="IE325_RS43120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87390"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_190075682.1"
                     /transl_table=11
                     /translation="MSPTNSRSSATSRRRFLTAGGALALGPLLAACGSDDKDTTGSQAE
                     TTRSGGPWSFKDDRGRAAKTENKPERIVAFVSTAAALYDYGIDCTGIFGPSEPVDGKPN
                     PQAGDMNVSELTSLGTAWGQFNVEKYAALQPDLLVSNMFPPPELWFVPEESKKKVEALA
                     PTVGISVARTSLLNPLKRTAELAESLGADLSAKKVTDAKARFEKAIETLRTTAKGNGGL
                     KVMAITGDKDNFYVAVPDSYCDLNYFKDLGVEFVEGKNSDEWGFWEFLSWENADKYHAD
                     LIMVDNRSASMSLKQLNDKATWRQLPAVKAGQTTPWSMEERFSYAGWAPVVERLAAAVE
                     KTKKLKA"
     misc_feature    2185..2203
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 27.71"
                     /tool="antismash"
     gene            2383..2634
                     /locus_tag="IE325_RS43125"
                     /old_locus_tag="GCM10018780_87410"
     CDS             2383..2634
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE325_RS43125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10018780_87410"
                     /product="hypothetical protein"
                     /protein_id="WP_190075683.1"
                     /transl_table=11
                     /translation="MELHAQHASKVHDAAAELDEQGWGALLIPGLAGGDIIGDAERLLR
                     ATKNAAVAIGVLGIWGCSATELAAEHPHAGSMKVISSS"
     gene            2684..3013
                     /locus_tag="IE325_RS43130"
                     /old_locus_tag="GCM10018780_87420"
     CDS             2684..3013
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014686.5"
                     /locus_tag="IE325_RS43130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87420"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_190075684.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 4.4e-08, bitscore:
                     25.6, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGVNPLAPGLLLDLPPLMDVDPNCKPMGVRLWLPDADSVQSCIDK
                     AAFHQSLTRHSIPTPRTWLPEEIDQVPDNTPLVVKPRRGHGAQNVHFVDRRDHPRFLSV
                     SAEHR"
     gene            <3191..>3358
                     /locus_tag="IE325_RS43135"
                     /pseudo=""
     CDS             3191..>3358
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387019.1"
                     /locus_tag="IE325_RS43135"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="DUF1684 domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRAGGDGPTLAIDFHRAWNLPCEYTDLATCPLPPTENRLPVAIEA
                     GEKIPLERAAA"
     gene            complement(3479..4654)
                     /locus_tag="IE325_RS43140"
                     /old_locus_tag="GCM10018780_87430"
     CDS             complement(3479..4654)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019067940.1"
                     /locus_tag="IE325_RS43140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87430"
                     /product="cytochrome P450"
                     /protein_id="WP_190075685.1"
                     /sec_met_domain="p450 (E-value: 7.3e-23, bitscore: 73.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTAGCSPLGAATTLAELARDPHPRLAQLRAHEPVSWLPELDGWL
                     VTRRDLALSVMRDAATFTVDDPRFSTAQVVGPSMLSLDGDRHTRHREAFAAPFRPREVR
                     GGFASFIERETDRLITALEPAGAVELRRAFAGPLAVAVVTEALGLVGTTTDTVLRWYDD
                     IVRSVSDITAGRAAGPAGAAAYAQLRTAVETTITSRGASSLLGSAADRLTPPEVASNAA
                     VLMFGGIETTEAMITNALLHLLSYPRQLALVRADFDHLDGAIEESLRLEPGAAVVDRYA
                     TRDTVLGPATIHRGDLVTVSLTGANRDPADFPDPDRFDVRRENARLQLAFAQGPHYCLA
                     AHLARLEARIALQRLLERLPALRLDPDRPTAPYGLVFRKPPSLHVLWDSPD"
     cand_cluster    4668..51546
                     /SMILES="CC(=O)CC(=O)C(=O)O"
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(hglE or hglD)"
                     /kind="single"
                     /product="hglE-KS"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    4668..51546
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[24667:31546](-)"
                     /cutoff="20000"
                     /detection_rule="(hglE or hglD)"
                     /neighbourhood="20000"
                     /product="hglE-KS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(24668..31546)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(hglE or hglD)"
                     /neighbourhood="20000"
                     /product="hglE-KS"
                     /protocluster_number="2"
     gene            4916..6466
                     /locus_tag="IE325_RS43145"
                     /old_locus_tag="GCM10018780_87440"
     CDS             4916..6466
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669872.1"
                     /locus_tag="IE325_RS43145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87440"
                     /product="amino acid permease"
                     /protein_id="WP_190075686.1"
                     /transl_table=11
                     /translation="MSGAASVGYQQELRRGMGGFASFAAGFSFVSILTTVFQLFGLGFG
                     LGGAAFFWTWPLVFAGQLLVALCFAELAARWPISGAIYQWSSRLAGTTVGWFTGWIMII
                     GQILTVAAAAIAAQVVLPGIWSGFQFVGGPGADPSVASSTGAQNAVLLGCVLLVVTTVV
                     NILGIRQMAAATSVGVMIEIVGVIALVLVLFFLPERGPQVVVHNTGWAGEGSYLGAFLA
                     SSLMAAYVMVGFDSAGELAEETHSPRRTTPRTILRALVISGVGGALLIIAGLLAARSLT
                     DGNLAAGGLSWVLTDRLGEVLGRLLLCCVAVAVFACTLAVQTSGARMIYSMAREGALPF
                     HRYLGKVSSRTGTPIITSIVVGVGAAIALLVNVRQSAIFTALSSLCIAMLYLAYLGVTL
                     PLLVARIRRRGTDRLPDGVDETGRPLFSLGRWGTVVNTLAVLFQIGMAVNLLWPRAEIY
                     DLTEGTWWLQWSALLFIGLSLAIGAGYFLARRLHLRIELRHVPHTHVEPPAEAVPEPA"
     gene            6548..7465
                     /locus_tag="IE325_RS43150"
                     /old_locus_tag="GCM10018780_87450"
     CDS             6548..7465
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669871.1"
                     /locus_tag="IE325_RS43150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87450"
                     /product="urea amidolyase associated protein UAAP1"
                     /protein_id="WP_190075687.1"
                     /transl_table=11
                     /translation="MTKTEGPTAATPHGRHPTANPLQPTGVRDLHLTDSVRSARDDARA
                     QGGQAGEWMPYLPASTTPHCPPGVDPADLVWAETVAPGGYTHKVLARGSRLRFDDPTGD
                     ACAHLLLFNALEPVERLNVADTQKIPWQAYLGVNHPLLSGDGRVMAVVPGDSSGRHDAF
                     CGTTTDAWNERKYGDARPEGPSPSGRGLFVKAAAKHGLSRRDLPPGVSFFQGVRVEADG
                     ALTWRGSAGPGTHVELVAEMPLLVLVANVAHPLDPRSAYVVGPLRVHAWRGLATGPGEE
                     RFSATPELHRAYLNTVDYCEARGL"
     gene            7467..8282
                     /locus_tag="IE325_RS43155"
                     /old_locus_tag="GCM10018780_87460"
     CDS             7467..8282
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009326999.1"
                     /locus_tag="IE325_RS43155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87460"
                     /product="urea amidolyase associated protein UAAP2"
                     /protein_id="WP_190075688.1"
                     /transl_table=11
                     /translation="MATSRTEETVPTAKVLNNYPTTSGGTVATAVPVGAVYAEGSPLDW
                     GASLVDGAVVLDERVAPNAPWSAVVAKGHVLTIVDVGGNQSADCIIYDAHDPQERYSVP
                     DTLAWQGNAYVRTGTVLRSNEGRPLMTVVANEIDRQDTIGGACGKESNTLRYGHHVMFH
                     HGCRENFLAEAARRGLGVRDLVSNLNWFMNVPVEADGSLGIVDGMSAPGRRVAVRAETD
                     VLVLVSNCPQMNNPCNDFNPTPLRMIVVDPGRPAGAGEATSQSTPEDVA"
     gene            8279..11869
                     /gene="uca"
                     /locus_tag="IE325_RS43160"
                     /old_locus_tag="GCM10018780_87470"
     CDS             8279..11869
                     /EC_number="6.3.4.6"
                     /GO_function="GO:0004847 - urea carboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019627 - urea metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="uca"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669869.1"
                     /locus_tag="IE325_RS43160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87470"
                     /product="urea carboxylase"
                     /protein_id="WP_190075689.1"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 5.5e-10,
                     bitscore: 31.3, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRPTTVLVANRGEIARRVIRTARRMGLATVAVFSDADRAAPHVR
                     EADHAVRLGPAPARDSYLRADAIVGAALDHGAGIIHPGYGFLSENAAFARAVEEAGLCF
                     AGPTVDQITAFGEKHTARALAKAAGVPLLAGTELLASAEEAATAAESIGLPVMVKATGG
                     GGGIGMQSCATADEVRAAFARVAALAESNFASAGVFLERLVRPARHVEVQVFGDGTGRI
                     AVIGDRDCSLQRRNQKVVEEAPAPALPDRVRALLHDSSRRLLASVGYRGAGTVEFVYDP
                     VRGEAAFLEVNTRLQVEHPVTEEAYGVDLVALMLELARDGRVDDGVFERDWTPTGHAVQ
                     ARVYAEDPGRDSLPSSGLITRAVFPGQDADPIPGVRVDGFAETGLDVSPYYDPMLAKVI
                     VYGADRDAAFDVLGEALGASRVDGIVTNLGLLRSLAVRDEVRAAVHSTSTLAATADPEP
                     RIDVLVPGAMTTVQDLPGRLGYWHVGVPPSGPFDPVSFAEANLAVGNPAGVPALEVTAG
                     GLSVRFSDATVVAVTGAPVPVTVDGTAAALWEPVPVPAGATLVVGTAQGPGLRTYVAVR
                     GGIDVPEYLGSASTFTLGGFGGHGGRALFAGDVLRPAAAPAATGRPTPPERRPAITSHW
                     RIGVTEGPHAAPEFFTREDIDTLYATDYKVHHNSARTGIRLIGPRPRWARQDGGEAGLH
                     PSNIHDTPYAVGALDFTGDTPIILGPDGPSLGGFVCPAVVASGELWKLGQLRPGDTVRF
                     VPVKEAEAAALDSRRASPTLVSTGGDGDDGILGRLQATDTRPAVTYRRDGDDNVLVEYG
                     PMTLDLSLRMRVHALQETLAAHAPEGIVDVTPGIRSLQIHTDARRLRARDLTALLRELE
                     DEVPPTGELVVPSRTVRLPLSWDDPATRLAIERYMAGVRDDAPWCPWNIEFIRRINGLE
                     SADDVYRTVFDASYLVLGLGDVYLGAPVATPLDPRHRLVTTKYNPARTWTAENSVGIGG
                     AYLCVYGMEGPGGYQFVGRTVQIWNRFRRGGLFQDSPWALRFFDRIEWYPVTAEELLEL
                     RAETDAGRGHFDTREGTFSIAEYNAFLTAEADSIASFRRRQGAAFEAEKERWRAAGEFD
                     RDDDPEPPAADTVVVPEGAIPVTAPFTATVWQTVAQAGTTVAEGDPILSLEAMKMESEV
                     SAPASGTLLEIYVKPGEQVAPGQVLAAVRA"
     gene            11875..13524
                     /gene="atzF"
                     /locus_tag="IE325_RS43165"
                     /old_locus_tag="GCM10018780_87480"
     CDS             11875..13524
                     /EC_number="3.5.1.54"
                     /GO_function="GO:0004039 - allophanate hydrolase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019627 - urea metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="atzF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669868.1"
                     /locus_tag="IE325_RS43165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87480"
                     /product="allophanate hydrolase"
                     /protein_id="WP_190075739.1"
                     /transl_table=11
                     /translation="MTPAERAEAAYDRVEAADRPEIWIHLRPREEVLAEAAGIDPGLPL
                     AGLVVAVKDNIDVAGLPTTAGAPSYAYRPDADAPAVARLRAAGALVLGKTNLDQFATGL
                     VGTRSPYGAVRNAWDPARISGGSSSGSAVAVALGIADLALGTDTAGSGRVPAALNGVVG
                     VKPTKGLVPVSGVVPACYTLDCVTVLARDLRLARAAAEIIEGPDPADPLSRTGTQLPPP
                     PARPRVAVPAEENLHGMADGWREAFAAAVTCLASTGVEIVEVDVTPLLEAAQLLYGGAF
                     VAERYAAVGDHLDKHRDLIGTDLDPTVAAIILAGREKTAVDWAADTARLAALGAAARTA
                     LDGCAALLTPTTTWHPTLEEVAADPVGANARMGRFTNFANLLDYASLAVPAGFVDGLPF
                     GVMLTGPAFSDRALAALAERFANPGLELFVVGAHLTGQPLNAQLVQAGGTLVGPARTAA
                     RYRLHALATRPLKPGLVRTAEGGAGIEGEIWRLPAAGFGALTAAVPAPMAIGTVELADG
                     GRISGFLVEPYAVENAPDITGFGGWRAYLASL"
     gene            13599..14282
                     /locus_tag="IE325_RS43170"
                     /old_locus_tag="GCM10018780_87490"
     CDS             13599..14282
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669867.1"
                     /locus_tag="IE325_RS43170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87490"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_190075690.1"
                     /transl_table=11
                     /translation="MKTTRPRQGRPRHTPPSDPNASGREQILDAAGALFVEHGIAATST
                     RMIAERVGIRQASLYYHFATKDEILAELLATSVRPSLQMVDRVQAWVPERASAAAALYA
                     VAATDVRTLSRTPYNIGTLYLLPEVLAERFDTFRADRDRLQRSYGALGASAATEDVTGR
                     MPPDRLGELLIQLVEVVIQIRRTRDPEAADTDAIASSCLRLCGLGEPGVVAARDEAGVL
                     LSRLA"
     gene            complement(14306..>14813)
                     /locus_tag="IE325_RS46485"
                     /pseudo=""
     CDS             complement(14306..>14813)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009716300.1"
                     /locus_tag="IE325_RS46485"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="type III effector protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="PDAAETQDVGPEQALASLLLLPHMREQLAGR"
     misc_feature    complement(14619..14621)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            15393..15827
                     /locus_tag="IE325_RS46495"
                     /old_locus_tag="GCM10018780_87520"
     CDS             15393..15827
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.5"
                     /locus_tag="IE325_RS46495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87520"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_229912468.1"
                     /transl_table=11
                     /translation="MAVDSSLTMIAQARDRGVPRGVVADGHRLPFAAGQFDGAWADRVL
                     QHVVEPGRVLDDLLRVVRPGGRVALADPDYDTQVLDINDQELARRVLRFRADAGLRNGA
                     LAHRHAGLLAARGLHDITAEARTLVVRDPLAADHVMGLRT"
     gene            complement(16543..17658)
                     /locus_tag="IE325_RS43180"
                     /old_locus_tag="GCM10018780_87540"
     CDS             complement(16543..17658)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071394.1"
                     /locus_tag="IE325_RS43180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87540"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_190075691.1"
                     /transl_table=11
                     /translation="MATTNQPPDTPDTPAPPPPASDAERVARLRPAYQAELADGIARFF
                     EPRRTDCPWCGARQLRRRLRTKDHLQRKPGTFTLDQCRDCGHTFQNPQLSAAGLDFYYR
                     DFYDGLYAEKIGGALDSDAARKRNRDRAAAMRRHARPKRWLDVGTAGGDFCLAAKEALP
                     GTAFDGLDIGAHVLGAQQSGRIERAYQGFLPDLADELAGQYDAVSMFHCLEHTTDPKAQ
                     LAAVHTVLRPGGHLIIEVPNPESPFGRLFGRYWLPWFQPQHQHFVTMRNLRRALTELGF
                     TVVATDREESHIPVDFTALVGLYVLRLLPFRDEPWLPRPPGRLGAAVTKTVFWAGIPFC
                     FPMYALDRLLAPLIRRSRFSNAFRVIARREE"
     gene            complement(17718..18902)
                     /locus_tag="IE325_RS43185"
                     /old_locus_tag="GCM10018780_87550"
     CDS             complement(17718..18902)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062: glycosyltransferase, MGT family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006382188.1"
                     /locus_tag="IE325_RS43185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87550"
                     /product="glycosyltransferase"
                     /protein_id="WP_190075692.1"
                     /sec_met_domain="MGT (E-value: 7.9e-41, bitscore: 132.8,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRFLFVVPPLVGHVNPAVSVAAELTRCGHRAAWAGLPGFVGELA
                     GPDAEVYPCDVPTLPERPAALRGAAALRFLWEEFLVPLAGAMAPGVRRAVEGFRPDVVV
                     ADQQTLAGALVAERLGVPYATASTTPAEFSDALDGMPKVAQWTAGLVAELRARLGDPGC
                     THDPRFSPDLVLSFTTPELAGPGPQLPQLRYVGPAFTRRPAADFPWEWLDEHRATVLVS
                     LGTANTGLGARFLAECAAAARERGRRLQAVLADPGGVLDGESDADLLVLPRIPQLPLLR
                     RASAMVSHAGQNTVAECLWHGVPLVVAPIRDDQPLIAGQVTGAGAGVRVRFGRADRRRI
                     GAALDAVLDGPAYRAAARRVGDSFRAAGGAAAAAAYLEKFAAQKPREPQESRER"
     gene            complement(18899..19708)
                     /locus_tag="IE325_RS43190"
                     /old_locus_tag="GCM10018780_87560"
     CDS             complement(18899..19708)
                     /NRPS_PKS="Domain: Abhydrolase_1 (28-147). E-value:
                     7.4e-30. Score: 96.3. Matches aSDomain:
                     nrpspksdomains_IE325_RS43190_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071396.1"
                     /locus_tag="IE325_RS43190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87560"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_229912469.1"
                     /sec_met_domain="PF00561 (E-value: 1.6e-26, bitscore: 85.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.3e-23, bitscore:
                     77.0, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 3.6e-08, bitscore:
                     26.1, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTIEAGGIRLNVERLSGAPTPAPGPPQTVVLVHGIATDNLTSYY
                     FTIAPALAAAGHDVVMYDQRGHGRSSRPPRGYGVEDFSGDLDALLDALALEGPVHLIGN
                     SFGGTVALAYALRRPERVAGILMLESEPPTAAWAKKMSGILAGSAHQLHDERTLPWIEE
                     TYGRHEARLVRWATRLLHGTSIAEDIGSCPVPAEESWQSLHVPVCAVYGATSDLADTAP
                     WLESLLPRCRTLTVPGHGHSVLVGTPETVVPLVLDWLRDGHRELVAP"
     aSDomain        complement(19268..19624)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS43190_Abhydrolase_1.1"
                     /evalue="7.40E-30"
                     /label="IE325_RS43190_Abhydrolase_1.1"
                     /locus_tag="IE325_RS43190"
                     /protein_end="147"
                     /protein_start="28"
                     /score="96.3"
                     /tool="antismash"
                     /translation="TVVLVHGIATDNLTSYYFTIAPALAAAGHDVVMYDQRGHGRSSRP
                     PRGYGVEDFSGDLDALLDALALEGPVHLIGNSFGGTVALAYALRRPERVAGILMLESEP
                     PTAAWAKKMSGILAG"
     CDS_motif       complement(19364..19423)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS43190_0001"
                     /evalue="6.60E-07"
                     /label="NRPS-te1"
                     /locus_tag="IE325_RS43190"
                     /protein_end="115"
                     /protein_start="95"
                     /score="21.8"
                     /tool="antismash"
                     /translation="EGPVHLIGNSFGGTVALAYA"
     gene            complement(19705..20004)
                     /locus_tag="IE325_RS43195"
                     /old_locus_tag="GCM10018780_87570"
     CDS             complement(19705..20004)
                     /GO_function="GO:0000036 - acyl carrier activity [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PP-binding (24-67). E-value: 6.7e-08.
                     Score: 24.7. Matches aSDomain:
                     nrpspksdomains_IE325_RS43195_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173581.1"
                     /locus_tag="IE325_RS43195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87570"
                     /product="acyl carrier protein"
                     /protein_id="WP_190075693.1"
                     /sec_met_domain="PP-binding (E-value: 5.4e-08, bitscore:
                     25.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSPATTGPAYAAVLAEVTDALHTVLDDLELDDTPITPDTRFVED
                     LDLESIDLVTLTAELGGRYGDRVDFPAWFASLELSDIIGLTVGQLVQYIAGCLR"
     aSDomain        complement(19804..19932)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS43195_PP-binding.1"
                     /evalue="6.70E-08"
                     /label="IE325_RS43195_PP-binding.1"
                     /locus_tag="IE325_RS43195"
                     /protein_end="67"
                     /protein_start="24"
                     /score="24.7"
                     /tool="antismash"
                     /translation="VLDDLELDDTPITPDTRFVEDLDLESIDLVTLTAELGGRYGDR"
     aSModule        complement(19804..24626)
                     /complete
                     /domains="nrpspksdomains_IE325_RS43200_PKS_KS.1"
                     /domains="nrpspksdomains_IE325_RS43200_PKS_AT.1"
                     /domains="nrpspksdomains_IE325_RS43195_PP-binding.1"
                     /locus_tags="IE325_RS43195"
                     /locus_tags="IE325_RS43200"
                     /monomer_pairings="mal -> mal"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     gene            complement(20001..24659)
                     /locus_tag="IE325_RS43200"
                     /old_locus_tag="GCM10018780_87580"
     CDS             complement(20001..24659)
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (11-474). E-value:
                     2.9e-116. Score: 380.8. Matches aSDomain:
                     nrpspksdomains_IE325_RS43200_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (660-868). E-value: 9.6e-35.
                     Score: 112.3. Matches aSDomain:
                     nrpspksdomains_IE325_RS43200_PKS_AT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127426.1"
                     /locus_tag="IE325_RS43200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87580"
                     /product="type I polyketide synthase"
                     /protein_id="WP_190075694.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 2.2e-66, bitscore:
                     216.3, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 3.7e-116, bitscore:
                     380.8, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.2e-34, bitscore: 112.3,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPTAPQHRQPVAIVGMAVTLPGACDLAAFWHNLVTGADAISEVP
                     KARWDADTYYDPDGRRGLDGVYCRRGGFVDGLDALAAFDPTVFGLMPDSVPGTEPDQLI
                     ALRTAAAALADAGKAALPEDRSRVGVVLGRGGYLSDGLARLDQRMRTSAQLVRTLHELL
                     PELDGERLDAVRMAFTAALGGEQSPESVIGLVPNFAASRVANRLDLRGPAYTVDAACAS
                     SLVALDQAVGALAAGSCDVMLAGGVHHCHDITLWSVFSRLRALSPSQRIRPFHRDADGV
                     LMGEGTGVVVLKRLADARRDGDRIYAVVRGVGVAGDGRAGSLVNPDPGGQARAVRLAWA
                     AAGLDPAAPGSLGLLEAHGTGTPGGDRAELAALAEVFGPPDPDAGPDAVIGSVKSMIGH
                     TMPAAGVAGLVKAALAVHHGTLLPTLHCDDPHPALRVTRFAPAQQARHWDGDVRRAAVS
                     AFGFGGINAHVVLESVPEPVPAPAWPPAPASAPAPASTPAVAPAAPAPGGPGAGPAACA
                     DRAEVAEPPRLLRLAAATPQDLAELLDADDTELRAAAAEGGARGAGGARVAVLDPTDRR
                     LALARKAVARARTWGGRSDVWCAPRPVLGTGGGKIAFLCPGLEAEFEPRAKDVARHFGL
                     PAPHWPDARVGDVARHGAAVVGLGRLLAGTLARIGVRPDALAGHSVGEWTAMAVGGMYA
                     DAEVDAFLRDFDPATLRVPGLAFAAFGTGADQVDAELAAYPDVVVSHDNAPHQTVVCGP
                     HDQVEALTGWLRGAGVLGRLLPFESGFHTPMLAPYLTSIEKAARGFTLHPPRVPVWSAT
                     TAAPFPTDEAAARALFLRHLLEPVRFRQLTTALYDAGFRAFVQLGQGQLPALVDDTLTS
                     RACLTLSANTPRHSGLSQLYRVAAGLWSHGAEPDFAALRAGAAPRSTAAPARTAETGPT
                     AETVRTATESPRAVPAPVTVPLTLGSGLVSLDAATRDRLRSTLREAPAPGLDRLAAVAA
                     RSPVAAELRSLLGETADTAAEVAELFAAAAAPRRTAPAAPPPEPSATGAVPPPAATSRA
                     TTLRISLDTMPYLADHCFFRQPAHWPEIADRWPVVPATTLVQHMIDAVPGPGRAVAVHD
                     ARFLQWTVAAPPTEATVTARPEGQGRYAVEFGRHARATVETAHGHDTAPRPRPWRADAP
                     ESRPAASARQMYDDRWMFHGPRFRGVTEIGALGERHVRGVLTTPSAPGALLDNVGQLLG
                     YWLMATHPDRTIVFPTGVEEIRFHGPPPEQGTALDCHIRVTTVTDTALVADAQLARDGE
                     VWAEIRGWRDRRFDSPPEVDPVKRRPEHNTLSETQEGGWQLVFERWPDPASREIYMRSQ
                     LAGPEREQYAGHPPRGRRQWLLGRIAAKDAVRRHLWAHGAGPVFPAEIRVANDPGGRPR
                     PEGVHGRELPPLELSLAHCREAAVALVHPAADSPGTGTGIDIEEIVERPETTYDAILAP
                     DERAPFTGLGGGPGWLTRFWAAKEAAAKAEGTGLGGRPRDFTAVEFEDGARALTVRAPS
                     GRLRRIRLADVTNPPGLPTRTYAVAWTEESPS"
     aSDomain        complement(22056..22679)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS43200_PKS_AT.1"
                     /evalue="9.60E-35"
                     /label="IE325_RS43200_PKS_AT.1"
                     /locus_tag="IE325_RS43200"
                     /protein_end="868"
                     /protein_start="660"
                     /score="112.3"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: (unknown)"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LLAGTLARIGVRPDALAGHSVGEWTAMAVGGMYADAEVDAFLRDF
                     DPATLRVPGLAFAAFGTGADQVDAELAAYPDVVVSHDNAPHQTVVCGPHDQVEALTGWL
                     RGAGVLGRLLPFESGFHTPMLAPYLTSIEKAARGFTLHPPRVPVWSATTAAPFPTDEAA
                     ARALFLRHLLEPVRFRQLTTALYDAGFRAFVQLGQGQLPALVDDT"
     CDS_motif       complement(22581..22652)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS43200_0004"
                     /evalue="6.90E-10"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="IE325_RS43200"
                     /protein_end="693"
                     /protein_start="669"
                     /score="30.9"
                     /tool="antismash"
                     /translation="GVRPDALAGHSVGEWTAMAVGGMY"
     aSDomain        complement(23238..24626)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS43200_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="2.90E-116"
                     /label="IE325_RS43200_PKS_KS.1"
                     /locus_tag="IE325_RS43200"
                     /protein_end="474"
                     /protein_start="11"
                     /score="380.8"
                     /tool="antismash"
                     /translation="VAIVGMAVTLPGACDLAAFWHNLVTGADAISEVPKARWDADTYYD
                     PDGRRGLDGVYCRRGGFVDGLDALAAFDPTVFGLMPDSVPGTEPDQLIALRTAAAALAD
                     AGKAALPEDRSRVGVVLGRGGYLSDGLARLDQRMRTSAQLVRTLHELLPELDGERLDAV
                     RMAFTAALGGEQSPESVIGLVPNFAASRVANRLDLRGPAYTVDAACASSLVALDQAVGA
                     LAAGSCDVMLAGGVHHCHDITLWSVFSRLRALSPSQRIRPFHRDADGVLMGEGTGVVVL
                     KRLADARRDGDRIYAVVRGVGVAGDGRAGSLVNPDPGGQARAVRLAWAAAGLDPAAPGS
                     LGLLEAHGTGTPGGDRAELAALAEVFGPPDPDAGPDAVIGSVKSMIGHTMPAAGVAGLV
                     KAALAVHHGTLLPTLHCDDPHPALRVTRFAPAQQARHWDGDVRRAAVSAFGFGGINAHV
                     VLESV"
     CDS_motif       complement(23427..23504)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS43200_0003"
                     /evalue="7.50E+00"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="IE325_RS43200"
                     /protein_end="411"
                     /protein_start="385"
                     /score="-0.1"
                     /tool="antismash"
                     /translation="PDAVIGSVKSMIGHTMPAAGVAGLVK"
     CDS_motif       complement(23982..24029)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS43200_0002"
                     /evalue="1.40E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE325_RS43200"
                     /protein_end="226"
                     /protein_start="210"
                     /score="17.2"
                     /tool="antismash"
                     /translation="GPAYTVDAACASSLVA"
     CDS_motif       complement(24033..24098)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS43200_0001"
                     /evalue="8.60E+01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="IE325_RS43200"
                     /protein_end="209"
                     /protein_start="187"
                     /score="-3.5"
                     /tool="antismash"
                     /translation="PESVIGLVPNFAASRVANRLDL"
     misc_feature    complement(24174..24176)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(24668..31546)
                     /locus_tag="IE325_RS43205"
                     /old_locus_tag="GCM10018780_87590"
     CDS             complement(24668..31546)
                     /NRPS_PKS="Domain: PKS_KS(Trans-AT-KS) (684-1123). E-value:
                     1e-123. Score: 405.4. Matches aSDomain:
                     nrpspksdomains_IE325_RS43205_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (1237-1528). E-value: 1.7e-60.
                     Score: 196.8. Matches aSDomain:
                     nrpspksdomains_IE325_RS43205_PKS_AT.1"
                     /NRPS_PKS="Domain: PP-binding (1695-1740). E-value:
                     9.2e-07. Score: 21.1. Matches aSDomain:
                     nrpspksdomains_IE325_RS43205_PP-binding.1"
                     /NRPS_PKS="Domain: PKS_KR (2014-2237). E-value: 1.3e-38.
                     Score: 124.7. Matches aSDomain:
                     nrpspksdomains_IE325_RS43205_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hglE-KS: hglE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010356776.1"
                     /locus_tag="IE325_RS43205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87590"
                     /product="type I polyketide synthase"
                     /protein_id="WP_190075695.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 3.5e-72, bitscore:
                     235.3, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="hglE (E-value: 8.2e-127, bitscore: 415.4,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2.2e-60, bitscore: 196.8,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.2e-06, bitscore:
                     21.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHTVIGVSPLGAPDPRLVAAVCRAGGSGVLDLGPGARATREALA
                     LLRQWAPGSHGVRVPADCALRPGELWAPAPTGTRRTADPAAAGPCTVLLAPDAPWTVAG
                     VRAAARAAAADPAVLAEVRGTDEAVRAVADGVTGLVVRGEESGDPCGEHSTFVLLQRVL
                     GAVPADLPVWACGGIGPHTAAAAVLAGARGVVLDIQLALLDEAGTAPAAAGLLRAADGT
                     ETVVVDGCRVLDRSRPGLPAVLRDRPLPLGQDAFLAARFAERYGTVDRALAAVTEGIDA
                     AVADDGAVLRGGSPMCRALGTALPVVQGPMTRVSDQARFAAAVADGGGLPFVALALAGP
                     EQTRTLLEQTKSALGDRSWGVGILGFVPEEIRTAQLEAVRELRPSHAVIAGGRPSQAAA
                     LEAEGIRTFLHVPSPGLLGQFLAAGVRRFVFEGAECGGHIGPRNSFPLWEAQLAVLEDF
                     LDAAADDGHTDGGDAADPQDVQVLFAGGIHDERSAAMVAALAAPLTTRGAAVGVLMGTG
                     YLFTEEAVECGAIRPLFQRAALDARSTTLLHTAPGHTTRCLPSAFSDTYQEVKDELRTQ
                     GIPERQVWQELERLNVGRLRIASKGVERVGDELLDVDEERQREAGMFMAGEVAVLRSAV
                     TTVAALHHAVTDGAADFYGRRTAELAADVRDAGGTVPARNPAPTPEPLDIAVVGMAGMF
                     PGAADLPAYWAQVLAGADAITEVPDTRWDPALHFGADAEADDVSASKWGGFLPPIPFDP
                     LAYGIPPASLAAIEPVQLLALEAARRALADAGLDRRAFPRERTCVVFGAEAGSDISGAA
                     TLRSVLPSYVGRLPEDLEEQLPKLTEDSFPGMLANVIAGRIANRLDLGGANYTVDAACA
                     SSLAAVDAACKELACGAADVALCGGADLHNGINDYLLFSSAHALSPTGRCRTFDAAADG
                     IALGEGVACLVLKRRADAERDGDRIYAVIEGVGSASDGRSLGLTAPRPEGQRAALERAY
                     AQARVSPAEVGLIEAHGTGTVVGDRTELGTLTRLFEDAGAAPGGCVVGSVKSQIGHTKC
                     AAGLAGLIKTALALHTGVRPPTLHIDVPNPVWTGPDSPFVFHSEARPWAEPAARRVAGV
                     SAFGFGGTNFHVVLRAHADAGAPPRQSHDVWPAELFVFRTRATAEELAALAASGHWRLR
                     DLARTAAQRAETGPGPLLGAVVAESVTELPHLIRDLLDGTPGRSGVFPATGAPAGAADG
                     DGESNDGGKVAFLFPGQGSQRPGMFAELFTAFPELGRHLYHAPAAALFPPAAFDAAERA
                     AQVARLTDTRHAQPALGAVGLAAYDTLTAVGVRPDMAAGHSYGELVALCAAGALDPDTL
                     GDLSRERAEAILAATGAQGSDPGTMAAAVASAEQVTRVLAGAGLAERVVVANHNAPAQS
                     VLSGPTDAAAEAVDALTDAGFAVRPLPVACAFHSPLVAGAVSRFAEILTAYAVRGPEFP
                     VWANLTGTRYAGDPAQIRADLAEQIAAPVRFADQIEAMYDAGARIFVECGPGTVLTGLV
                     GQILGDRPHVAVPFEPRPDAGLRGHLEALARLAAAGVPVAPARLFSGRDTALADPAAVP
                     ERPGWTVDGHLVRTADGRPVPGALRPARRISGIQRTEKRTSEATTMGEREELLREFLRN
                     SREMLAAQRDVLLGYFGAPPAPQAAPPALEPLPAPAPAALAAAPAPAPAPVGVDVLAEV
                     LAVIAERTGYPVEMVGAESDLEADLSVDSIKRTEIAGELGRRLLGSGADLRSLPDADLE
                     ELTRERTAAGIADWLRARAKALADPDPAPALATSAPVAEESPAPLTGQAPHRYLLRPAP
                     LDPPPVPGAEGAAQLRGKRFLIVADDTPLARALVTRLTTLGALAARGGPDTAQLAGHTG
                     PVDGVLHLGALAGTEQQLLPAKLTVLQQLLLRGPRRLLCPRLPDDTSGLDGFVRTAARE
                     YPDTVVRTVELDPDEPATEQAEALVGELLAPDREPVVLRTCGVRRAPVPYESPLGPPVS
                     SGAGPASSGAAAAAALGLGPESVVVLAGGARGITARFTLALAAAARCRVELLGRTPLDD
                     GTGGHHELAHATDLPALRAALAARGGLSTAEIDREAGRVLARREIATTLAEVHDAGGRA
                     RYRALDLRDAEAVQQAVKETYATYGRIDGVVHAAGVIEDRLLAEKDPVSFERVYGTKVD
                     GARALLSALRRLPQLPAFTVMFGSVAAVYGNRGQADYAAANDALARLGRLWRADTGSRT
                     VTVHWGPWAPAGAHGGMVGPELGREYARRGIELIDPEEGVLALLRELAWGEPETDEVVL
                     TASGR"
     aSDomain        complement(24836..25504)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS43205_PKS_KR.1"
                     /evalue="1.30E-38"
                     /label="IE325_RS43205_PKS_KR.1"
                     /locus_tag="IE325_RS43205"
                     /protein_end="2237"
                     /protein_start="2014"
                     /score="124.7"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="VVVLAGGARGITARFTLALAAAARCRVELLGRTPLDDGTGGHHEL
                     AHATDLPALRAALAARGGLSTAEIDREAGRVLARREIATTLAEVHDAGGRARYRALDLR
                     DAEAVQQAVKETYATYGRIDGVVHAAGVIEDRLLAEKDPVSFERVYGTKVDGARALLSA
                     LRRLPQLPAFTVMFGSVAAVYGNRGQADYAAANDALARLGRLWRADTGSRTVTVHWGPW
                     A"
     CDS_motif       complement(24884..24988)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS43205_0007"
                     /evalue="4.90E-13"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE325_RS43205"
                     /protein_end="2221"
                     /protein_start="2186"
                     /score="41.6"
                     /tool="antismash"
                     /translation="FTVMFGSVAAVYGNRGQADYAAANDALARLGRLWR"
     aSDomain        complement(26327..26461)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS43205_PP-binding.1"
                     /evalue="9.20E-07"
                     /label="IE325_RS43205_PP-binding.1"
                     /locus_tag="IE325_RS43205"
                     /protein_end="1740"
                     /protein_start="1695"
                     /score="21.1"
                     /tool="antismash"
                     /translation="EVLAVIAERTGYPVEMVGAESDLEADLSVDSIKRTEIAGELGRRL
                     "
     aSModule        complement(26327..29494)
                     /complete
                     /domains="nrpspksdomains_IE325_RS43205_PKS_KS.1"
                     /domains="nrpspksdomains_IE325_RS43205_PKS_AT.1"
                     /domains="nrpspksdomains_IE325_RS43205_PP-binding.1"
                     /locus_tags="IE325_RS43205"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(26963..27835)
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS43205_PKS_AT.1"
                     /evalue="1.70E-60"
                     /label="IE325_RS43205_PKS_AT.1"
                     /locus_tag="IE325_RS43205"
                     /protein_end="1528"
                     /protein_start="1237"
                     /score="196.8"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFPGQGSQRPGMFAELFTAFPELGRHLYHAPAAALFPPAAFDAAE
                     RAAQVARLTDTRHAQPALGAVGLAAYDTLTAVGVRPDMAAGHSYGELVALCAAGALDPD
                     TLGDLSRERAEAILAATGAQGSDPGTMAAAVASAEQVTRVLAGAGLAERVVVANHNAPA
                     QSVLSGPTDAAAEAVDALTDAGFAVRPLPVACAFHSPLVAGAVSRFAEILTAYAVRGPE
                     FPVWANLTGTRYAGDPAQIRADLAEQIAAPVRFADQIEAMYDAGARIFVECGPGTVLTG
                     LVGQILGDRP"
     CDS_motif       complement(27530..27604)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS43205_0006"
                     /evalue="1.90E-09"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="IE325_RS43205"
                     /protein_end="1339"
                     /protein_start="1314"
                     /score="29.5"
                     /tool="antismash"
                     /translation="GVRPDMAAGHSYGELVALCAAGALD"
     CDS_motif       complement(27788..27838)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS43205_0005"
                     /evalue="2.10E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE325_RS43205"
                     /protein_end="1253"
                     /protein_start="1236"
                     /score="17.0"
                     /tool="antismash"
                     /translation="FLFPGQGSQRPGMFAEL"
     CDS_motif       complement(28019..28090)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS43205_0004"
                     /evalue="1.10E+01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="IE325_RS43205"
                     /protein_end="1176"
                     /protein_start="1152"
                     /score="-0.6"
                     /tool="antismash"
                     /translation="ELAALAASGHWRLRDLARTAAQRA"
     aSDomain        complement(28178..29494)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS43205_PKS_KS.1"
                     /domain_subtypes="Trans-AT-KS"
                     /evalue="1.00E-123"
                     /label="IE325_RS43205_PKS_KS.1"
                     /locus_tag="IE325_RS43205"
                     /protein_end="1123"
                     /protein_start="684"
                     /score="405.4"
                     /specificity="transATor: (unknown)"
                     /tool="antismash"
                     /translation="IAVVGMAGMFPGAADLPAYWAQVLAGADAITEVPDTRWDPALHFG
                     ADAEADDVSASKWGGFLPPIPFDPLAYGIPPASLAAIEPVQLLALEAARRALADAGLDR
                     RAFPRERTCVVFGAEAGSDISGAATLRSVLPSYVGRLPEDLEEQLPKLTEDSFPGMLAN
                     VIAGRIANRLDLGGANYTVDAACASSLAAVDAACKELACGAADVALCGGADLHNGINDY
                     LLFSSAHALSPTGRCRTFDAAADGIALGEGVACLVLKRRADAERDGDRIYAVIEGVGSA
                     SDGRSLGLTAPRPEGQRAALERAYAQARVSPAEVGLIEAHGTGTVVGDRTELGTLTRLF
                     EDAGAAPGGCVVGSVKSQIGHTKCAAGLAGLIKTALALHTGVRPPTLHIDVPNPVWTGP
                     DSPFVFHSEARPWAEPAARRVAGVSAFGFGGTNFHVVLRA"
     CDS_motif       complement(28394..28438)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS43205_0003"
                     /evalue="6.30E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE325_RS43205"
                     /protein_end="1051"
                     /protein_start="1036"
                     /score="9.5"
                     /tool="antismash"
                     /translation="GSVKSQIGHTKCAAG"
     CDS_motif       complement(28499..28543)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS43205_0002"
                     /evalue="3.40E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE325_RS43205"
                     /protein_end="1016"
                     /protein_start="1001"
                     /score="10.1"
                     /tool="antismash"
                     /translation="IEAHGTGTVVGDRTE"
     CDS_motif       complement(28919..28966)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS43205_0001"
                     /evalue="7.90E-04"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE325_RS43205"
                     /protein_end="876"
                     /protein_start="860"
                     /score="12.0"
                     /tool="antismash"
                     /translation="GANYTVDAACASSLAA"
     misc_feature    complement(31802..31815)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     misc_feature    32051..32061
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.79"
                     /tool="antismash"
     misc_feature    complement(32109..32123)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.88"
                     /tool="antismash"
     gene            complement(32217..32747)
                     /locus_tag="IE325_RS43210"
                     /old_locus_tag="GCM10018780_87600"
     CDS             complement(32217..32747)
                     /EC_number="3.1.-.-"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE325_RS43210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10018780_87600"
                     /product="dienelactone hydrolase family protein"
                     /protein_id="WP_190075696.1"
                     /transl_table=11
                     /translation="MVMTLNTNALWDFPADRSRQQLAALTYLTAQSTVKNRIDPGRLAL
                     MGWSMGGGSLQSAASTPSLKAAIPLAPWDLSDVSSRITVPTMIFGADGDTVASVDDFAL
                     PFYNGLVSAPDKSLIVLKDTDHFTFTDPNTTIAQYSVSWLKRFVDNDTRYDQFLCPTPN
                     DPNTVVFQITCPL"
     gene            32841..33416
                     /locus_tag="IE325_RS43215"
                     /old_locus_tag="GCM10018780_87610"
     CDS             32841..33416
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007265998.1"
                     /locus_tag="IE325_RS43215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87610"
                     /product="IS607 family transposase"
                     /protein_id="WP_190075697.1"
                     /transl_table=11
                     /translation="MNLTEWARVQGVHPQTAYKWFREGTLPVPAQRVGPRTILVNIAAN
                     AAPEVVGGVGLYARVSSHDQKPDLERQTARLVGWAAEAGHRVVRVESEVGSGMNGARSK
                     ARRLLADPDVTTVVVEHKDRLGRMNVELVEAALAAAGRRLVVLDDGEVEDDLVRDMVEV
                     LTSFCARLYGRRSARNRAKAALEAAEHG"
     gene            33409..35052
                     /locus_tag="IE325_RS43220"
                     /old_locus_tag="GCM10018780_87620"
     CDS             33409..35052
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014177554.1"
                     /locus_tag="IE325_RS43220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87620"
                     /product="IS200/IS605 family accessory protein TnpB-related
                     protein"
                     /protein_id="WP_190075698.1"
                     /transl_table=11
                     /translation="MAEPKKKLRQISRPFVADGPTGVSIRDRLKGLTGEDERILRLVSE
                     HMGRLASLDLARRCRDGLEHSADTWAARKRDLTVLSSSRWAGSVTSNTHDQWGLSRRAQ
                     HAHLQSLGAGISMVRHRLSLPVGEKGSRGKPGGYRSKHEWFTKTRRLAILEGEFERVTA
                     AREAGKVSIVRGGRKLLNNRHNLAAAHLTAEQWRDRWDAARWFLTADGESGKRLGNETI
                     RVTLDGEISIKLPAPLAEYANAPRGRYVLAAKVTFPHRGDEWRDRIEGNRAVAYRIHYD
                     VERGRWYLDASWTRKELPVVPLDALRAGGVIGVDMNADHLAAWRLDTHGNPTGNPRRFD
                     YDLTGTAPHRDAQLRHALTRLLHWAKATGAAAIAIEDLDFTDSTTREKHGRKKRFRQLI
                     SGVPTSKLRARLLSMCAETGIGVIAVDPAYTSLWGGQHWQKPLTTPKRPVTRHQAAGVA
                     IARRALGHRIRRRTAPPRQHQSDAGGHRTAQARPGDRRREGNRPRVPGPRTRSDGAERG
                     RNAATQNTQNRSGCSAEYEFWQQDSLPLSR"
     gene            complement(35032..35379)
                     /locus_tag="IE325_RS43225"
                     /old_locus_tag="GCM10018780_87630"
     CDS             complement(35032..35379)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012946.5"
                     /locus_tag="IE325_RS43225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87630"
                     /product="hypothetical protein"
                     /protein_id="WP_229912470.1"
                     /transl_table=11
                     /translation="MQVRHPDIPGLDTFPGTAFHSARWNHEVDLTGQRVAVVGTGASTV
                     QFLPEIQPKATHVDVFQSTPQWVLLKPDYLLPPGLHRFFAHHPAARRALRGLHHWTQEA
                     IGVPFLPTEWE"
     gene            35378..36316
                     /locus_tag="IE325_RS43230"
                     /old_locus_tag="GCM10018780_87640"
     CDS             35378..36316
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1092: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE325_RS43230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10018780_87640"
                     /product="hypothetical protein"
                     /protein_id="WP_190075700.1"
                     /transl_table=11
                     /translation="MLIAAACANIRKQDATETSLPRRGLHRAFARAMLRTAVSKVHQDL
                     RIWSTKGYEPRPLRHPRLLRPLEALARFYLRTSVRDRALRRALTPDYRLGGRRLITSGT
                     YSAALTRPNVRLHPTRVTAVEGSDVIGADGTRTRADIIVLATGFRIGDLPLAPQLHGID
                     GTLAQTWADSRRAYLGTSVSGYPNPFLLIGPNLLTGTTAVPTILEAQLRSITTALNHLR
                     TSRASALDVKPEAARQQALHEALRNTVYNTTGGTAYYFGLPGINTFCWPWSTAGLVKRL
                     HSFDPDVYTWRLPLPTQAGAERDGLPAHRSG"
     gene            complement(36615..37370)
                     /locus_tag="IE325_RS43235"
     CDS             complement(36615..37370)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013899.5"
                     /locus_tag="IE325_RS43235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="urease accessory protein UreD"
                     /protein_id="WP_229912472.1"
                     /transl_table=11
                     /translation="MRHSPHPRQPQRTRHHAPAATQRRPVPPPTPAHRQKPRQGRDHRR
                     DERPLGGDRLTIDVTAGDRAALEVTTAAATLALRGPTTAPATYDVRLTVGEHASLRWLP
                     QPLISAADSNLRQTCTVELASTARLLLREEQLLGRANEDPGHLVSRLLVHRAGRPLLDQ
                     QTAYGDPEPGWDGPAILHGHRAVGQLLLVDPQMSMRRSPILLRPRSREGCAVLAPLAGG
                     PALLATAVAPTSSTLRELLDEALTHALGQ"
     gene            complement(37501..38196)
                     /gene="ureG"
                     /locus_tag="IE325_RS43240"
                     /old_locus_tag="GCM10018780_87660"
     CDS             complement(37501..38196)
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0016530 - metallochaperone activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0019627 - urea metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="ureG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018093168.1"
                     /locus_tag="IE325_RS43240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87660"
                     /product="urease accessory protein UreG"
                     /protein_id="WP_190075701.1"
                     /transl_table=11
                     /translation="MHLDHPETMPQRHTHSAEPLRADGTRRALRVGLGGPVGSGKTASV
                     AALCRTLREGWSIAVVTNDIYTREDAEYLLREAVLPPERITAVETGACPHTAIRDDISA
                     NLEAVEHLEETLRPLDLVLIESGGDNLTATFSKGLVDQQIFVIDVSSGDDIPRKGGPGI
                     TTADLLLINKTDLAPHVGADLATMATDAKRQRGDLPVIFTSLTSDDGIRDVADWITAHL
                     TEWHHKAAA"
     gene            complement(38226..38900)
                     /locus_tag="IE325_RS43245"
                     /old_locus_tag="GCM10018780_87670"
     CDS             complement(38226..38900)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018957903.1"
                     /locus_tag="IE325_RS43245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87670"
                     /product="urease accessory protein UreF"
                     /protein_id="WP_190075702.1"
                     /transl_table=11
                     /translation="MSRAALLLLADGRFPAGGHAHSGGIEAAIAHQAVHDTDSLQTFCR
                     GRLHTTGLTTAGLAAAAAAGVNPLLLDDAADARTPAPALRAVARRLGRQMMRAARATFP
                     SKDLERLAAARPQGAHQPIVLGLAARAAGLTPLDAAYAAAYENASGPATAAVRLLSLDP
                     LDASSLLAHLSTDLDAVATAAARAADRATAEGVDALPSASSPLLDITGEQHAAWTVRLF
                     AS"
     gene            complement(39021..41060)
                     /gene="ureC"
                     /locus_tag="IE325_RS43250"
                     /old_locus_tag="GCM10018780_87680"
     CDS             complement(39021..41060)
                     /EC_number="3.5.1.5"
                     /GO_function="GO:0009039 - urease activity [Evidence IEA]"
                     /GO_function="GO:0016151 - nickel cation binding [Evidence
                     IEA]"
                     /GO_process="GO:0019627 - urea metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="ureC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004946315.1"
                     /locus_tag="IE325_RS43250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87680"
                     /product="urease subunit alpha"
                     /protein_id="WP_190075703.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 8.2e-62, bitscore:
                     201.6, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTPQGQVPSQAPKPVEGRPPKPSNELTRADYTTLYGPTTRDRVR
                     LADTDLTLEIEADWSGGPSYSGNEMVFGGGKVIRESMGMSHLARDGKDGTGTATGHEPV
                     DTVITGALILDWWGVVKADIGIRDGRITAIGKAYNPETMDKITSFEMPDRGPAKQVPPV
                     TPTNFVIGPSTEVISGNGRILTAGGVDTHVHFICPGEIHEALASGVTTLIGGGTGPAEG
                     SKATTVTPGAWHIRRVFEALDEFPVNIGLLGKGSTMNEHELNAQVDAGVCGLKIHEDWG
                     ATPAVIDRALDVCEERGVQLALHADSLNESGFLESTRAAFTGDGRDAGGKFTPKKARAI
                     HVFHVEGAGGGHAPDMIELVKEPNVLPASTNPTRPLTVNTVKEHVDMMIVCHHLNPDIP
                     ADIAFADSRIRPSTMAAEDLLHDMGAISMMSSDAQAMGRIGEMITRTWQTAHVMKSRYG
                     PLKEDLDAAKVRPITDDTNHSFNDQQKQPNDNFRARRYVAKYTINPAITHGIDGYVGSV
                     QTGKLADLVLWEPKFFGVKPHMLLKGGQLAYAQVGDANASIPTPQPYQPRPVWGSTGRS
                     PGRNSVNFVALGVADKLNGDGTSSNPGLGLDKDFVDITSTRHVTKADMKLNDTVPDSLE
                     VDHNSFEVTIGGATTTDTRTELNGATVPRSYVTEVPLAQRYFLF"
     gene            complement(41057..41506)
                     /locus_tag="IE325_RS46885"
     CDS             complement(41057..41506)
                     /EC_number="3.5.1.5"
                     /GO_component="GO:0035550 - urease complex [Evidence IEA]"
                     /GO_process="GO:0043419 - urea catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012902.5"
                     /locus_tag="IE325_RS46885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="urease subunit beta"
                     /protein_id="WP_308437718.1"
                     /transl_table=11
                     /translation="MCCDEDDTAARYDAIYFNVHLDGDAQGVSLQGDATALPGPGRTKI
                     KVKNESDRPIQVASHYHFAEVNPGLKVVSIEVPAGQTVPDDRSLWNCEAAKGRRLNIAA
                     GTSVRFEPGDECCVELVQIQGAVTAGGGNTSDLTKIQGLREGMVR"
     misc_feature    41514..41526
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            complement(<41615..41911)
                     /locus_tag="IE325_RS46890"
                     /pseudo=""
     CDS             complement(<41615..41911)
                     /GO_function="GO:0009039 - urease activity [Evidence IEA]"
                     /GO_function="GO:0016151 - nickel cation binding [Evidence
                     IEA]"
                     /GO_process="GO:0043419 - urea catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014671284.1"
                     /locus_tag="IE325_RS46890"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="urease subunit gamma"
                     /pseudo=""
                     /transl_table=11
                     /translation="MHLTPHERERLLIHVAADVAQRRRDRGLRLNYPEVMALLTVHVFE
                     AARDGKTVSDIMDSGRQLFTRDEVMDGVTEMIKNVQVEATFPDGTKLVTIHDPI"
     gene            complement(<42269..>42358)
                     /locus_tag="IE325_RS47190"
                     /pseudo=""
     CDS             complement(<42269..42358)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036771.1"
                     /locus_tag="IE325_RS47190"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDVPAETVGRSGATAWRQLHAVLLDESTRT"
     gene            <42437..43313
                     /locus_tag="IE325_RS43260"
                     /pseudo=""
     CDS             <42437..43313
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014043975.1"
                     /locus_tag="IE325_RS43260"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="UvrD-helicase domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="PRLDAHFLLLDEAQDTNPVVEQIFLAHRDHAQLVMVGDSAQAIYQ
                     WRGAKDIMTGFDGTQLPLSQSFRFGPDLAAEANRWLHLADAPISASPAPPPCSRRPAGR
                     RALPHQRRRHGPGHDPHGGRIPGRPGRGRRQPAGPGPRGP"
     gene            43470..44192
                     /locus_tag="IE325_RS43265"
                     /old_locus_tag="GCM10018780_87720"
     CDS             43470..44192
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024950.5"
                     /locus_tag="IE325_RS43265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87720"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_190075704.1"
                     /transl_table=11
                     /translation="MLLADRTAIVHGGSGAVGAAIARGFAREGAVVHLTGRTVPPLEDV
                     ARRIRDDGGAAHVAGLDATDRDAVDRHADMVAAQGGGIDICFNATSNDDLQGIPLLDMA
                     VADVLRPVTKAVTTTLTTATAAARHMVRGGSGVILVMGGGREAISNLGGSHIAWSALAG
                     VCRQLASELGPQGVRVAWLLSPGSPAPGEEDRAAEGALLTKRPRYDDVANAAVFAASDW
                     ARTMTAFELNLTGGLVVD"
     gene            complement(44208..44600)
                     /locus_tag="IE325_RS43270"
                     /old_locus_tag="GCM10018780_87730"
     CDS             complement(44208..44600)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF013752.5"
                     /locus_tag="IE325_RS43270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87730"
                     /product="transposase"
                     /protein_id="WP_268256398.1"
                     /transl_table=11
                     /translation="MQKRGGADTGPSPVDRRKTGSKHHLICDGRGTPLKVVTAANVNDV
                     IQTLALVHGIPPVAGRPGRPRRRPNSLLGDKGYDSNPNRQELHKRRILPVISRKGAPNI
                     KGLGKLRYVVEQTFALLHRIFIRPAR"
     misc_feature    complement(44564..44579)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.28"
                     /tool="antismash"
     gene            complement(44632..44928)
                     /locus_tag="IE325_RS43275"
                     /old_locus_tag="GCM10018780_87740"
     CDS             complement(44632..44928)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF024736.5"
                     /locus_tag="IE325_RS43275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87740"
                     /product="transposase"
                     /protein_id="WP_190075706.1"
                     /transl_table=11
                     /translation="MSTRPWIVDDELWVLIEPLLPPWPEKAPGPRPVADRLCLQGILYE
                     LHNDIAWQLLPPELGFGSGQTCWRRLDRWQQAGVFEQMHRVLLAELNAAGELD"
     misc_feature    complement(45232..45248)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.6"
                     /tool="antismash"
     misc_feature    45275..45288
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.2"
                     /tool="antismash"
     gene            45630..45875
                     /locus_tag="IE325_RS43280"
     CDS             45630..45875
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE325_RS43280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_190075707.1"
                     /transl_table=11
                     /translation="MYATRTQACRIDGVLYETYVVRNGVRTTTGEVNLLLINYSYGSTS
                     ESRIAHQLDVTAFNGWGDALKGSYSGNARVGYSCTK"
     cand_cluster    46309..56512
                     /candidate_cluster_number="4"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="3"
                     /tool="antismash"
     protocluster    46309..56512
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[51308:51512](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="3"
                     /tool="antismash"
     proto_core      51309..51512
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="3"
     gene            complement(47604..48047)
                     /locus_tag="IE325_RS46780"
     CDS             complement(47604..48047)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013188.5"
                     /locus_tag="IE325_RS46780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cation:proton antiporter"
                     /protein_id="WP_268256399.1"
                     /transl_table=11
                     /translation="MGPPPRPTARPPRRRTTHAEILGLTLIVAALAELIHASAPVGAFL
                     VGLTLTGETADRARAVLSPLRDLFAAVFFLAIGLTVSPDDLLPLLPAALALAAITTATK
                     LVTGHYAVSRDQVGRRGRGWLRNIHEWCRWSDQCPEGRHRLRF"
     gene            complement(47975..48382)
                     /locus_tag="IE325_RS46785"
                     /old_locus_tag="GCM10018780_87790"
     CDS             complement(47975..48382)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013188.5"
                     /locus_tag="IE325_RS46785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87790"
                     /product="cation:proton antiporter"
                     /protein_id="WP_268256400.1"
                     /transl_table=11
                     /translation="MPSAMVDLVLNAVPGAVAGWLLGLDGIGILALADATYISSSGIVA
                     RLLADLRRLSNRETPAILSVLVMEDFAMASHLPLLAVLASGGPWWQAVLGVLIAVGAVL
                     AAFTASDRWGHHLGRLLAHPDAEQLMLKSSA"
     gene            complement(48645..49121)
                     /locus_tag="IE325_RS43295"
                     /old_locus_tag="GCM10018780_87810"
     CDS             complement(48645..49121)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018891191.1"
                     /locus_tag="IE325_RS43295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87810"
                     /product="cation:proton antiporter regulatory subunit"
                     /protein_id="WP_190075709.1"
                     /transl_table=11
                     /translation="MPTCLISHPLGLGYEFTNHEGDRVGIVAAWTGDFDLVVYAGGDPD
                     EARPVVRLNNEEADTVAEILGAPRITERFADLTKEVPGLVSGQVEVRTSSPFADQPLGQ
                     TRARSRTGASIVAIVRGEDVIASPTPDHVLQAGDVLVVIGTHEGITGVEQIVQG"
     gene            complement(49426..50496)
                     /locus_tag="IE325_RS43300"
                     /old_locus_tag="GCM10018780_87820"
     CDS             complement(49426..50496)
                     /EC_number="2.1.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013087.5"
                     /locus_tag="IE325_RS43300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87820"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_190075710.1"
                     /sec_met_domain="PCMT (E-value: 1.9e-07, bitscore: 23.3,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAPRELDEAKVEAFMEKALGDLSGTMTIGLCHLGDRLGLFKGLA
                     TSGPAGSRELADRLDLNERYVREWLRGLTGAGYLEEPEPGRFILPAEHAPALADESGPM
                     FLGGVYQMMPAALTPYERLCEAFRGGGGVPQSEYPDILWDGMSRFTGSWFESVMVDDWL
                     STFPHVVERLQRGIDVADVGCGAGRALIVLAKAFPHSRFTGFDNFPAQVERARQNAEKA
                     GVADRVTFETIDATQGLPGRYDLITTFDVIHDAAEPKQLLSAIRAAVKDDGDYLMLEIN
                     CADRPEDNVGPVATMFYGFSMFYCMTTSLANDGAALGTCGMPEAVVRSLCAEAGFRDVA
                     RSTADDPFNVLYDIKP"
     gene            51309..51512
                     /locus_tag="IE325_RS43305"
                     /old_locus_tag="GCM10018780_87830"
     CDS             51309..51512
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: strepbact"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311933.1"
                     /locus_tag="IE325_RS43305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87830"
                     /product="hypothetical protein"
                     /protein_id="WP_190075711.1"
                     /sec_met_domain="strepbact (E-value: 2.9e-17, bitscore:
                     55.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSAPQVETVEIADAELDNVSGGLHANVCAGPTAVSDADLLAQVD
                     AVKNQVLGAAAQYNHVSVSASL"
     gene            51996..52613
                     /locus_tag="IE325_RS43310"
                     /old_locus_tag="GCM10018780_87840"
     CDS             51996..52613
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010984818.1"
                     /locus_tag="IE325_RS43310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87840"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_190075712.1"
                     /transl_table=11
                     /translation="MVLGIRGQLRLQAYDGELGAAVARAQEGDEVAFAVVHRRVQPGLL
                     GYLRGLVGDDAEDVASDAWLEIARDLGRFKGDGAGFRGWTATIARHRAYDHLRRQKVRP
                     RLALEHDALDLPRPHHTRDHAPDPISTEAALQLVRGLPRDQAEAVLLRVVVGLDEPVAA
                     RVLGKRPGAVRAAGCRGLKRLARRLGGGGVAHEVPRTLGEST"
     gene            52656..53387
                     /locus_tag="IE325_RS43315"
                     /old_locus_tag="GCM10018780_87850"
     CDS             52656..53387
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992522.1"
                     /locus_tag="IE325_RS43315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87850"
                     /product="hypothetical protein"
                     /protein_id="WP_190075713.1"
                     /transl_table=11
                     /translation="MGEPHSDGSAPGRRRVHRSDAVSGPEGSALEALLAALPEAGADRK
                     GEQQAVAAFRAARDVGAHRVRTRRRDDWRPRGQRRAWHSVRAAVALSLASLTLSGVALA
                     AIGVVRSSDDGHGDRRRSQPSATASSQAGAGTPAAESHTPGASAALDHQATAQDTDAHC
                     RAYEAVKGRGKALDATAWRRLVEAAGGTRDVAAYCAEQLTHTAGDEQGRAEKTENAKKA
                     EKAAKPTKPAKTTKPEKPEKR"
     gene            complement(53823..54443)
                     /locus_tag="IE325_RS43320"
                     /old_locus_tag="GCM10018780_87860"
     CDS             complement(53823..54443)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020135062.1"
                     /locus_tag="IE325_RS43320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87860"
                     /product="PASTA domain-containing protein"
                     /protein_id="WP_229912476.1"
                     /transl_table=11
                     /translation="MLAALTGLTACGGNGPTNGTPADKPATPRQSTPTDQPTATQDTTT
                     RAETGSLPNMIGKGLQFAQDQAQEAGFYNLTSHDALGRGRNQALDRNWKVCFQTPKAGA
                     HPTSTQVDFATVKLEGTCPATDQGAATETPGSTMPDFKGKSVKVAREALAPITSITVND
                     ALGEGRVIIIESNWKVCSQEPAAGTRLEGQPVTLNAVKFEESC"
     misc_feature    54548..54564
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.66"
                     /tool="antismash"
     gene            55061..56332
                     /locus_tag="IE325_RS46790"
                     /old_locus_tag="GCM10018780_87870"
     CDS             55061..56332
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018092851.1"
                     /locus_tag="IE325_RS46790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_87870"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_190075715.1"
                     /sec_met_domain="Pkinase (E-value: 9.8e-58, bitscore:
                     187.8, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVAQRYRLDGRIGRGGMGEVWRATDELLGRTVAVKLLAAEADEA
                     ATRRFRREAEIAARVTDPHVVALYDAGAHEGRLFLVMEFVDGGSLAGELAVHGVLGPER
                     VACLAAQIAEGLSVAHRQGVIHRDIKPANLLLTSDGTVKIADFGVARIAHETAVALTAS
                     GQLLGTSPYLAPERAVGRPAGPASDVYSLGCVLYELLTGHSPFWGETAAAVVHQHVEAV
                     PARPGQLRSGLPGSFEDYLLRLLAKNPGHRPTAERVADWFTAWQNTRPPAASRLASPDT
                     QAHTARFSAAPASRTPRRRRPTGRRTAALLGLGAVALFGASVLIGATLGDNETRGPSGS
                     TAPSPSLSPSPSATTAATDPSTPQETRVATTAPPPPVPSATPTAHDTTTAATPTAPPSS
                     TAATTPSPSSTPPKKKADKHKPKR"
ORIGIN
        1 cggaagatcc tgcgcgactg ccgcctcaag gcgaaggcat ccaccacgcc atgctcggca
       61 tcgcccgcct gcacaacctc acctccgcca gatggacgtt cccgacgagc aatccgagca
      121 gacatggccc atcaaagatc attaacggga catccctgag ttaggtgtgc ctgaagtgcc
      181 tgatccggct tgtccggtgc ccgctccgtt gtgatcagtc ggcgaaccgg aagaggttga
      241 agcggtacgc ctccatgtcg cggcggcgta gtagtgaggc ggcgcgcagc atcaggcgat
      301 aggccgggtt gagccggcgg gccacggggg cggggaggcg ggcgaagctg caggagtcgg
      361 tcaggtgaac gcccgggcgc cagcgctcca gggccgtcgg gtcgtcgcag cgccagcgca
      421 tccgggccgc caccttgccc aggacgtcgt gactgtcctg gctgtccacc attcgcccgg
      481 cggcggtctc cagggcgagc agcgcgcctg gcagccgctc ggcgatcagg tcgaacaccg
      541 agtggacctg ctgctcctcc aggtagatga gcacggcctc cgcggccagg aagtacggcc
      601 cggggctctt gcgcacctcg tcggtccagg cagggtcggt gaccgagagg gcgagcatgc
      661 gcctgcggtc ggtgtcctgg aagaacgtgc gccgcagttc gatgacgtcg gggaggtcca
      721 ggtcgatcca gtgcaccgtg ccgttgtcga gccgttcgaa ccgggtgttg aggccggtgc
      781 cgatctccac gaccgtgccc ttggggtgcc gctggaggaa gtctgcgacc caggcgtcga
      841 acagcagggt ccgcaggttc gcgccgagga ggctcttggc accgtcgaac cgggtgaagt
      901 cgtagtcgat cgcgtcgacc atctccaccg cacgcgggtc gctgagcatg ccgtgccgct
      961 tgctggtctc caccgcacgg gcgtacagcg ggatgagcaa cgtctcctgg atgtcgccga
     1021 gttcgggtgg ccgcctgggc tcggtcacgg gatgcacctc ctgggctatg ccttgagctt
     1081 cttcgtcttc tccacggcgg cggcgaggcg ttcgacgact ggggcccaac ccgcgtagct
     1141 gaagcgctct tccatcgacc agggagtggt ctggccggcc ttgaccgcgg gcagctggcg
     1201 ccaggtggcc ttgtcgttga gctgcttcag ggacatggag gcggagcggt tgtcgaccat
     1261 gatgaggtcg gcgtggtact tgtcggcgtt ctcccagctg aggaactccc agaagcccca
     1321 ctcgtcggaa ttctttccct cgacgaactc cactcccagg tccttgaagt agttcaggtc
     1381 gcagtaggag tcggggacgg cgacatagaa gttgtccttg tcgccggtga tggccatgac
     1441 cttcagcccg ccgttgccct tcgccgtcgt acgcagcgtc tcgatggcct tctcgaagcg
     1501 ggccttggcg tccgtgacct tcttcgcgct caggtccgcg ccgagtgact cggcgagttc
     1561 agcggtgcgc ttgagcgggt tgagcaggga ggtgcgggcg acgctgatgc cgaccgtggg
     1621 agccagggcc tcgaccttct tcttgctctc ctcagggacg aaccacaatt ccggcggcgg
     1681 gaacatgttg ctgaccagca ggtccggctg gagtgctgcg tacttctcga cgttgaactg
     1741 gccccatgcg gtgcccaggc tggtcagttc ggacacgttc atgtcgccgg cctgcggatt
     1801 gggcttgccg tccaccggtt cgctggggcc gaagattccg gtgcagtcga taccgtagtc
     1861 gtacagggct gcggcggtgc tgacgaacgc gacgattcgc tccggcttgt tttcggtctt
     1921 cgctgcgcgg cctcggtcgt ccttgaaaga ccatggcccg ccgctcctgg tcgtctcggc
     1981 ctgcgagccg gtcgtgtcct tgtcatcgct gccgcaggcg gcgagcagcg ggccgagcgc
     2041 gagcgcgcca cccgcggtga ggaagcgtcg acgagacgtt gcggagctgc gggagttcgt
     2101 tggggacatg ggagcttctt ccgtgcacaa ggcagacaca ggcggcggac gagttccgaa
     2161 cagttaccgg acaggcatcg aaggtgaggg aaggctaacc taactgttcg tggggtggta
     2221 gtccctgcag ggaggacgcg gcgcgccgtc ggggccattc gggatgtcct cgtactcggt
     2281 ctcaggcccg ctgtggtccc cgcggagggg cggatcggtg ggtggtgtgc tccgcactgg
     2341 cgcggtggtg tccggccggt tggacgaacg ggtctgtgga gcgtggaact gcatgcgcag
     2401 catgcctcaa aggtgcatga cgctgcggcc gagctggacg agcagggctg gggagccctt
     2461 ttgatccccg gcttggctgg cggagacatc atcggcgacg cagagcggct gttgagagcc
     2521 accaagaacg cggctgtcgc catcggggta ctcggcatct ggggctgctc ggccacggaa
     2581 ctggctgccg agcatccgca tgccggaagc atgaaggtca tctcgagcag ctgacaagac
     2641 tgagcgaacc gccggcaccg cggatcgctg gtgggcccgc atcatgggcg tgaaccctct
     2701 cgcccccggc ctcctgctgg acctcccgcc gctgatggac gtagacccca actgcaagcc
     2761 gatgggggtg cgcctgtggc tgccggacgc cgactcggtg cagtcctgca tcgacaaagc
     2821 cgccttccac cagtcactga ccaggcacag catccccacc ccgcgcacgt ggctccccga
     2881 ggagatcgac caggtccccg acaacacgcc gctcgtcgtc aaaccacggc gcggccacgg
     2941 cgctcagaat gtccacttcg tcgaccgacg agaccacccc cgcttcctct cggtatcggc
     3001 ggaacaccga tgagaccaat cccgcaggcg cggcaagcac atgaggctgg gaatctgcgg
     3061 caaacgtgcc acgggaccaa cggggagcac gccgggggca gaacggccag ggcctcgcgg
     3121 agggacaacc tcttcaggcg cagggatgat ccccggatcg cctcgcttcc cgaagcccgc
     3181 gagggctgtt ccccgcgctg gcggagatgg tcccaccctc gcgatcgact tccaccgcgc
     3241 ctggaacctg ccctgcgagt acaccgacct ggccacctgc ccgctgccgc cgacggagaa
     3301 ccggctgccg gtcgcgatcg aggcgggcga gaagatcccc ctggagcgcg cggcagccgg
     3361 ccgggacctt cccgggcgga tcctcgcgcc catgtacctg cagatccgcg acgcacagcc
     3421 gcgatggcgc gttcccggcg cagccacggc gaactcggcg gcatacgcca atgagcagtc
     3481 agtcggggga gtcccacagc acatgcaggc tgggcggctt gcggaagacc aggccgtacg
     3541 gagcggtggg ccggtcgggg tccaggcgca gggcggggag gcgttcgagg agtcgctgga
     3601 gggcgatgcg ggcctccagg cgggcgaggt gcgcggcgag gcagtagtgc ggcccctgtg
     3661 cgaaggccag ttggagtcgc gcgttctcgc ggcggacgtc gaatcggtcg gggtcgggga
     3721 agtcggccgg gtcgcgattg gctcccgtga gggagacggt gaccaggtcg ccccgatgga
     3781 tcgtggccgg gccgagcacc gtgtcccgtg tggcgtaccg gtctacgacc gccgcgccgg
     3841 gttcgaggcg cagtgattcc tcgatcgcac cgtccaggtg gtcgaagtcg gctcggacca
     3901 aggcaagttg gcggggatag ctcaggaggt gcagcagcgc gttcgtgatc atcgcctcgg
     3961 tggtctcgat gccgccgaac atcaggacgg ccgcgttcga ggccacttcg ggcggcgtca
     4021 gcctgtcggc ggcggagccg aggagcgagg acgcgccccg ggaggtgatg gtggtctcca
     4081 cggcggtccg tagctgggcg taggccgcgg cgccggcggg tcccgccgcc cgtccggccg
     4141 tgatgtccga gacggaccgc acgatgtcgt cgtaccagcg cagcaccgtg tccgtggtgg
     4201 tgccgaccag cccgagcgcc tcggtgacga cggcgacagc gagcggtccg gcgaaggcgc
     4261 gtcgcagctc gacggcgccc gcgggttcca gtgcggtgat gagccggtcg gtctcccgct
     4321 cgatgaacga ggcgaagccg ccgcgcactt cgcgggggcg gaagggggcg gcgaaggcct
     4381 cacggtggcg ggtgtgccgg tcgccgtcga gggacagcat gctcggcccg acgacctgtg
     4441 cggtggagaa ccgggggtcg tcgacggtga aggtcgcggc gtcccgcatc acgctcagcg
     4501 cgaggtcgcg acgggtgacc agccagccgt ccagctcggg cagccaggac accggctcgt
     4561 gcgcgcgcag ctgcgcgagg cgtggatggg ggtcccgggc gagttcggcg agggtggtcg
     4621 cggcgccgag cggggagcag ccggccgttc tcatcgcgca cctcggccgt tcgctgggaa
     4681 accgttcatg gtcaaggcta acaaccgtgc tgagagccac agagagcgaa gcacctgctg
     4741 caagtcccgg ctgagagggg ccggttacac gacgttaacg cccgtgactc ggacgtgaga
     4801 ccgctccacc ccaccatcgc aatacctgtc agccgatagg taatcctcgt tcggaggtgc
     4861 ggtgatgaac ggatctgagc tcacccctgc gtcacatccc gtcgaaggcg ccgcaatgtc
     4921 cggcgccgcg tccgtgggct atcagcagga gttgcgtcgc gggatgggcg gcttcgcgtc
     4981 gttcgcggcg ggcttctcct tcgtgtcgat cctcaccacc gtcttccagc tcttcggact
     5041 cggattcggc ctcggcgggg cggcgttctt ctggacctgg ccgctggtct tcgcgggcca
     5101 gctcctggtt gccctgtgct tcgccgaact cgccgcgcgc tggccgatct ccggggcgat
     5161 ctaccagtgg tcgagccggc tggcgggcac cacggtcggc tggttcaccg gctggatcat
     5221 gatcatcggg cagatcctca ccgtcgcggc ggccgcgatc gccgcgcagg tggtgctgcc
     5281 cggcatctgg tccggcttcc agttcgtcgg cggaccgggc gcggacccgt cggtggcctc
     5341 gtcgaccggc gcgcagaacg cggtcctcct gggctgcgtc ctgctggtcg tcacgaccgt
     5401 cgtgaacatc ctcggcatcc gtcagatggc tgccgccacc agcgtcggcg tcatgatcga
     5461 gatcgtcggc gtgatcgcac tggtgctggt gctgttcttc ctgcccgagc ggggcccgca
     5521 ggtggtggtc cacaacaccg gctgggccgg ggagggcagt tatctcgggg cgttcctcgc
     5581 ctcctcgctg atggcggcgt acgtcatggt cggcttcgac tcggcgggcg agctggcgga
     5641 ggagacgcac agcccacgcc ggaccacgcc ccggaccatc ctgcgggcgc tggtcatctc
     5701 gggcgtcggc ggcgcgctgc tgatcatcgc ggggttgctc gcggcgagga gcctgaccga
     5761 cggcaatctg gcggccggcg gcctttcctg ggtgctcacc gaccggctcg gagaggtgct
     5821 gggccggctg ctgctgtgct gtgtcgcggt cgcggtgttc gcctgcaccc tcgccgtgca
     5881 gacctccggc gcacgcatga tttactccat ggcgcgcgag ggcgccctgc ccttccaccg
     5941 gtacctcggg aaggtctcgt cccgcaccgg tacgccgatc atcacctcga tcgtggtggg
     6001 tgtgggcgcc gcgatcgcgc tcctggtgaa cgtccgccaa tcggcgatct tcaccgcgct
     6061 ctccagtctc tgcatcgcca tgctctacct ggcctacctg ggcgtgacac tcccgctgct
     6121 ggtcgccagg atccggcgcc ggggcaccga ccggctcccg gacggcgtcg acgagacggg
     6181 ccggccgctg ttctcactgg gccgctgggg caccgtcgtc aacacgctcg cggtgctctt
     6241 ccagatcggc atggcggtca acctgctgtg gccgcgcgcg gagatctacg acctcaccga
     6301 gggcacctgg tggctccagt ggagcgcgct gctgttcatc gggctcagcc tcgccatcgg
     6361 cgccggttac ttcctcgccc gccggctgca cctccggatc gagctgcggc acgtccccca
     6421 cacgcatgtc gagccgccgg ccgaggcagt tccggagccc gcctgacggc tcggcgacag
     6481 aaccccggcc agcacgcatc acgggacgcg cctgacggcg taccgacgaa gggacgacgg
     6541 cacccccatg acgaagaccg aagggccgac ggccgccacg ccgcacggcc ggcaccccac
     6601 cgcgaacccc ctccagccca ccggcgtcag agacctgcac ctgaccgaca gtgtccgcag
     6661 cgcccgcgac gacgcccgcg cccagggcgg ccaggccggc gagtggatgc cgtatcttcc
     6721 ggcgtccacc accccgcact gcccgccggg agtggacccg gccgacctgg tgtgggcgga
     6781 gacggtggcg cccggcggct acacccacaa ggtcctcgcc cgcggcagcc ggctgcgctt
     6841 cgacgacccg accggtgacg cctgcgccca tctgctgctc ttcaacgcgc tggaaccggt
     6901 cgagcggctc aacgtcgccg acacccagaa gatcccctgg caggcgtacc tgggcgtgaa
     6961 ccacccgttg ttgtccggcg acggccgggt catggccgtc gtccccggcg actcctccgg
     7021 ccggcacgac gccttctgcg gcacgaccac cgatgcctgg aacgaacgca agtacgggga
     7081 cgcccgcccc gagggaccgt cgccgtccgg ccggggtctc ttcgtcaagg cggccgccaa
     7141 gcacggtctg agcaggcgtg atctgccgcc cggggtgtcc ttcttccagg gggtacgggt
     7201 cgaggcggac ggcgcgctca cctggcgggg cagcgcgggc ccgggcacac atgtcgaact
     7261 cgtcgcggag atgccgctcc tggtgctggt cgccaacgtc gcgcatccgc tggacccgcg
     7321 ctccgcctac gtcgtcggac ccctgcgggt gcacgcctgg cgtggtctgg cgaccggtcc
     7381 cggcgaggag cggttcagcg cgacgcccga attgcaccgg gcgtatctca acaccgtcga
     7441 ctactgcgaa gcccgggggc tgtgacatgg cgaccagtcg gaccgaggaa accgtgccca
     7501 ccgcgaaggt cctgaacaac taccccacca cgtcgggcgg caccgtcgcc accgccgtcc
     7561 cggtcggtgc cgtgtatgcc gagggctccc ccttggactg gggggcgagc ctggtcgacg
     7621 gcgccgtcgt cctggacgag agggtggcgc ccaacgcgcc ctggtcggcg gtggtagcga
     7681 aggggcacgt cctgacgatc gtcgacgtcg gcggcaacca gtccgccgac tgcatcatct
     7741 acgacgctca cgacccgcag gagcgctaca gcgttcccga cacgctggcc tggcagggca
     7801 acgcctatgt gcgcaccggc accgtcctgc gcagcaacga gggccgaccg ctgatgacgg
     7861 tcgtcgccaa cgagatcgac cgtcaggaca ccatcggcgg cgcctgcggc aaggagtcca
     7921 acaccctgcg ctacggccac catgtgatgt tccatcacgg ctgccgcgag aacttcctcg
     7981 ccgaggccgc ccggcgcggc ctgggcgtgc gggacctcgt ctccaacctc aactggttca
     8041 tgaacgtgcc cgtcgaggcg gacggctcgc tgggcatcgt cgacggcatg tcggcgcccg
     8101 gccgccgggt cgcggtgcgc gccgagacgg acgtcctggt gctggtgtcc aactgcccgc
     8161 agatgaacaa cccgtgcaac gacttcaacc cgacgccgct gcggatgatc gtcgtggatc
     8221 cgggccgtcc cgcgggcgcc ggcgaggcga cctcgcagag caccccggag gacgtcgcgt
     8281 gacccgcccc accactgtcc tggtcgccaa ccgcggtgag atagcgcgtc gcgtcatccg
     8341 cacggcgcgg cggatggggc tggccaccgt cgccgtcttc tccgacgccg accgggccgc
     8401 gccgcacgtc cgcgaggccg accacgcggt gcgcctcggt cccgcgcccg cccgtgactc
     8461 gtatctgcgc gccgacgcga tcgtcggggc cgcgctcgac cacggtgccg gcatcatcca
     8521 cccgggctac ggcttcctct ccgagaacgc cgccttcgcc cgcgccgtcg aggaggccgg
     8581 cctgtgtttc gcgggcccga ccgtcgacca gatcaccgcg ttcggcgaga agcacaccgc
     8641 ccgtgccctg gccaaggcgg ccggggtacc gctgctggcc gggaccgaac tcctcgcgag
     8701 cgccgaggag gccgccaccg cggccgagtc gatcgggctg cccgtgatgg tcaaggccac
     8761 cggcggtggc ggcggcatcg gcatgcagtc ctgcgccacc gccgacgagg tgcgggccgc
     8821 gttcgcccgg gtggccgcgc tcgccgagtc caacttcgcc tcggcgggcg tgttcctgga
     8881 gcgtctggtg cgcccggccc ggcacgtcga agtacaggtc ttcggcgacg gcaccggccg
     8941 tatcgcggtc atcggcgacc gtgactgctc gctccagcgc cgcaaccaga aggtggtgga
     9001 ggaggctccg gccccggcac tgcccgaccg ggtccgggca ctgctgcacg actcctcgcg
     9061 ccggctgctg gcttcggtcg gctaccgcgg cgcggggacc gtggagttcg tctacgaccc
     9121 ggtgcgcggg gaggccgcct tcctggaggt caacacgcgg ctccaggtcg aacacccggt
     9181 gaccgaggag gcgtacggcg tcgatctcgt cgcgctcatg ctggaactgg cccgggacgg
     9241 ccgggtcgac gacggggtgt tcgagcggga ctggacgccc accggacatg ccgtgcaggc
     9301 ccgggtctac gcggaggacc ccggcaggga ctcgctgccc tcctccggcc tgatcacccg
     9361 ggcggtcttc cccgggcagg acgccgatcc gatacccggt gtccgggtcg acggcttcgc
     9421 cgagaccggc ctggacgtct cgccgtacta cgaccccatg cttgccaagg tcatcgtgta
     9481 cggcgccgac cgtgacgccg ccttcgacgt gctcggcgag gccctgggcg cgagccgtgt
     9541 cgacggcatc gtcaccaacc tgggcctgct gcgttcgctg gccgtgcgcg acgaggtgcg
     9601 cgcggccgtg cacagcacga gcacgctcgc cgcgaccgcc gaccccgagc cgcgcatcga
     9661 cgtcctggtg cccggggcga tgaccaccgt gcaggacctg cccggccggc tcggctactg
     9721 gcatgtcggt gtgccgccga gcggcccttt cgacccggtc tccttcgccg aggccaatct
     9781 ggccgtgggc aatccggccg gggtgcccgc gctcgaagtg accgcgggcg gcctgtccgt
     9841 gcgcttctcc gacgccacgg tcgtcgccgt caccggcgct cccgttcccg tcaccgtcga
     9901 cggcacggcg gcggccctgt gggagccggt gccggtgccg gccggcgcca ccctggtggt
     9961 cggcaccgcg caagggcccg gtctgcgcac ctacgtggcc gtccggggcg gcatcgacgt
    10021 gcccgaatac ctgggcagcg cctcgacgtt caccctcgga ggcttcggcg gccacggcgg
    10081 gcgggcgctg ttcgccggag acgtgctgcg gcccgcggcc gcccctgccg ccaccggccg
    10141 cccaaccccg cccgagcgac gtcccgcgat cacctcgcac tggcggatcg gcgtcaccga
    10201 agggccgcac gcggcaccgg agttcttcac ccgcgaggac atcgacacgc tctacgccac
    10261 cgactacaag gtgcaccaca actcggcccg taccggcatc cgcctgatcg ggcccagacc
    10321 gcgctgggcc cgccaggacg gcggcgaggc gggactgcac ccctcgaaca tccacgacac
    10381 gccgtacgcg gtgggtgctc tggacttcac cggcgacacg ccgatcatcc tcggccccga
    10441 cgggccgtcc ctcggcgggt tcgtctgccc cgcggtcgtc gccagcggcg aactgtggaa
    10501 gctcggccag ctccgccccg gagacaccgt ccggttcgta ccggtcaagg aggccgaggc
    10561 cgccgccctc gactcccgcc gtgcctcgcc cacgctcgtc agcacgggcg gggacggcga
    10621 cgacggcata ctgggccgcc tgcaggccac cgacacccgc cccgccgtga cctaccgccg
    10681 tgacggcgac gacaacgtcc tcgtcgagta cggccccatg acgctcgacc tcagtctgcg
    10741 gatgcgggtg cacgcccttc aggagaccct ggccgcgcac gcgcccgagg gcatcgtcga
    10801 cgtcaccccc ggcatccgtt ccctccagat ccacaccgac gcccgccggc tcagggcccg
    10861 cgatctcacc gccctgctgc gcgagttgga ggacgaggtc ccgcccacag gcgagctggt
    10921 ggtgccctcc cgcacggtac ggctgccgct cagctgggac gacccggcga cccgtctcgc
    10981 catcgagcgg tacatggcgg gggtgcgcga cgacgccccg tggtgcccgt ggaacatcga
    11041 gttcatccgc cgtatcaacg gcctggagag cgccgacgac gtctaccgca cggtcttcga
    11101 cgcctcctac ctggtgctcg gcctcggcga cgtctatctc ggcgcccccg tcgccacccc
    11161 gctggacccc cggcaccgcc tggtcaccac caagtacaac ccggcccgca cctggaccgc
    11221 ggagaactcc gtcggtatcg gcggcgccta cctgtgcgtc tacggcatgg agggcccggg
    11281 cggttatcag ttcgtcggcc gcacggtgca gatctggaac cggttccgca ggggcggcct
    11341 gttccaggac tcgccgtggg ccctgcgctt cttcgaccgc atcgagtggt atcccgtcac
    11401 cgctgaggaa cttctagaac tgcgcgccga gaccgacgcc ggccgcggtc acttcgacac
    11461 ccgggagggc acgttctcga tcgccgagta caacgccttc ctgaccgccg aggccgattc
    11521 gatcgcctcc ttccggcgtc ggcagggtgc cgcgttcgag gccgagaagg aacgctggcg
    11581 ggccgccggc gagttcgacc gcgacgacga tcccgagccc ccggccgccg acaccgtcgt
    11641 cgtcccggag ggcgccatcc cggtcaccgc gccgttcacc gccaccgtct ggcagaccgt
    11701 cgcccaggcc ggcaccaccg tcgccgaggg cgacccgatc ctctcgctgg aggcgatgaa
    11761 aatggagtcc gaagtgagcg cccccgccag cggaacgctt ctggagatct acgtcaagcc
    11821 cggtgagcag gtcgccccgg gtcaggtact cgcggcggtg agggcatgag cgccatgacc
    11881 ccggccgaac gagccgaggc cgcctacgac cgcgtcgagg ccgccgaccg gcccgagatc
    11941 tggatccacc tcaggccgcg cgaggaggtg ctcgccgagg ccgccgggat cgatccgggg
    12001 cttccgctgg cggggctggt cgtagccgtc aaggacaaca tcgacgtggc cggcctgccc
    12061 acgaccgccg gcgcgccgtc ctacgcctac cggccggacg ccgacgcgcc cgcggtggca
    12121 cggctgcgcg cggccggcgc gctggtgctc ggcaagacca acctggacca gttcgccacc
    12181 ggcctggtcg gcacccgcag cccctacggc gccgtgcgca acgcctggga tccggcccgc
    12241 atctcgggcg gttcgtcctc gggctcggcc gtcgccgtgg cgctgggcat cgccgacctc
    12301 gcgctgggta ccgacacggc cggctccggg cgggtgcccg ccgccctgaa cggcgtcgtc
    12361 ggggtcaagc ccaccaaggg cctggtgccc gtgtccgggg tggttcccgc ctgctacacc
    12421 ctcgactgcg tgaccgtcct cgcccgcgac ctacggctcg cccgcgcggc cgcggagatc
    12481 atcgagggcc ccgaccccgc cgacccgctc tcccgcaccg gcacccagct gccaccaccg
    12541 cccgcgcgcc ccagggtcgc cgtcccggcc gaggagaacc tgcacggtat ggccgacggc
    12601 tggcgggagg cattcgcggc agcggtcacc tgcctggcga gcaccggagt ggagatcgtg
    12661 gaggtcgatg tcactccgct gctggaggcc gcgcaactgc tgtacggcgg tgccttcgtg
    12721 gccgagcggt acgccgccgt cggcgatcac ctggacaagc accgcgacct gatcggtacg
    12781 gacctcgacc ccaccgtcgc cgccatcatc ctggccggcc gggagaagac tgccgtcgac
    12841 tgggccgccg acaccgcccg cctcgccgcc ctcggcgccg ccgcccgcac ggccctggac
    12901 ggctgcgcgg cgctgctcac cccgaccacc acctggcacc ccaccctcga agaggtggcc
    12961 gccgacccgg tcggcgccaa cgcccgcatg ggccgcttca ccaacttcgc caacctgctg
    13021 gactacgcct cgctcgccgt ccccgccggg ttcgtggacg gtctgccgtt cggcgtgatg
    13081 ctcaccggcc cggccttctc cgaccgcgcc ctggcggcgt tggccgagcg gttcgcgaat
    13141 ccggggctcg aactgttcgt ggtgggcgcc cacctcaccg ggcagcccct caacgcccag
    13201 ttggtccagg cgggcggcac gctcgtgggc ccggcccgca ccgccgcccg ctaccggctg
    13261 cacgccctgg ccacccggcc gctcaagccg ggtctggtgc ggacggcgga gggcggcgcg
    13321 ggcatcgagg gcgagatctg gcggctgccc gccgccgggt tcggggcgct gaccgcggcc
    13381 gtgcccgcgc cgatggccat cggcaccgtc gaactggccg acggaggccg gatcagcggc
    13441 ttcctggtcg agccgtacgc ggtcgagaac gcgcccgaca tcacgggctt cggaggctgg
    13501 cgggcctatc tggcgtccct ctgacggggc gcgataccgg caggcacccg aagcccacgg
    13561 gcgccgggtg cccgccaccg gggtggcagg atggggttat gaagaccacg cggccgcgcc
    13621 aaggaagacc ccggcacacg ccgccgtccg atcccaacgc ctcgggtcgg gaacagatcc
    13681 tcgacgccgc cggtgcgctc ttcgtcgaac acggcatcgc cgccaccagc acccgcatga
    13741 tcgccgagcg ggtgggcatc agacaggcct cgctgtacta ccacttcgcc accaaggacg
    13801 agatcctcgc cgagctgctg gccacctcgg tccggccgag ccttcagatg gtggaccgcg
    13861 tccaggcatg ggtgccggag cgggcgagcg cggccgcggc gctctacgcg gtcgccgcga
    13921 cagacgtacg caccctgtcc cgcaccccgt acaacatcgg cacgctgtat ctgctgccgg
    13981 aagtgctggc cgaacggttc gacaccttcc gcgccgaccg ggaccgactc cagcgcagct
    14041 acggggctct cggtgcgtcg gcggcgaccg aggacgtcac cgggaggatg ccgcccgaca
    14101 ggctcgggga actgctgatc cagttggtgg aggtcgtcat ccagatccgg cgtacccggg
    14161 atccggaagc ggccgacacg gacgcgatcg cgtcgtcgtg tctgcggctg tgcgggctgg
    14221 gcgagccggg ggtggtggcc gcgagggacg aggcgggtgt gctgctgagc cgcctggcgt
    14281 gatcgacggc cgcccgacgc gcggttcagg gcggggtgag gtcgcccagt tgtgccgcga
    14341 tgtcgggatg ggcatccgtc aggtgagggc gaatggcgtc gaggggccga cgagctcggc
    14401 ggggtcgtcg tgggcgagcg ccgcgcggag ttggctgagc gggaagtggg ccccggcggc
    14461 cagatcggtg agcgcggaga aacgtcccgc gatgccgcac aggtcggcgg cattgtgccg
    14521 ggcccaggag gcggtggagc gttcggcggc gcggcgttcc cgggtggact acgcgttgct
    14581 cgctgacgga tcctgccggg cccggcaggt tacgcaggta acggcgttcg gcggcctggc
    14641 ggctggcgac gccgaggggg tgcgcgaggt cggcccagct ggcacccgct ttcgcgggcg
    14701 ctctcgatca gaccggttta ccgtccggcc agttgctcgc gcatgtgcgg cagcagcaga
    14761 agcgaggcca gggcctgttc cgggccgacg tcctgagtct cggcagcgtc gggggcgtcc
    14821 tcgtgtgcgg caggacggcg ttgggtgctc cacggtgtcc tctccccaca gcgactgtcc
    14881 gactgtgtgg gcacggtgcc ccccggatga ccggccagcc ggcgaccggg aggtgctggt
    14941 ggtgatcgtg ttcgttgcga ccgggccgcc accagtggag taacggccgc acccttgcct
    15001 ggcgcatcgg ctgttaccga ctcagccgac gctatgaact cgaagtcgcc cacttccgcg
    15061 ctgcactctc atctgctgcc gcagactcac caaatgagat gacgtcttac ctagtgcgct
    15121 atctgtgagg ttcaccggct tggtcgacac gtctagcgtg ctcccatgaa cgatcatggt
    15181 gttgctcacg gtttcacgtc ggtggacacg cagccccggc ccgccgagtg ggttgaggtc
    15241 ctggatcggt tgagcgcgga gccgttctac gccgcttaca agcagcggtt gcaggagttc
    15301 ctgcgtgccg agcccggcgg actgttcctt gaggtcggag caggtactgg gaacgccgct
    15361 gtggccctgc gctcgcgctg ggggccgagg tcgtggcggt cgacagctcc ttgacgatga
    15421 tcgcgcaggc acgggaccga ggagtgccac gtggggttgt cgcggacggg caccggctgc
    15481 cgttcgcggc gggtcagttc gacggcgcct gggctgatcg ggtcctgcag catgtcgtcg
    15541 aaccgggccg ggtgctggac gacttgctgc gagtggtccg tcccggcggc cgggtcgcct
    15601 tggcggaccc ggactacgac acccaggtgc tcgacatcaa cgatcaggag cttgcccgcc
    15661 gggtgttgcg cttccgggcc gatgcgggcc tgcgcaacgg tgcgctggcc caccggcacg
    15721 ccggactgct cgctgcccgt ggcctccatg acatcactgc ggaagctcgg actctcgtcg
    15781 tgcgcgaccc gctggcggcc gaccatgtca tgggcctgcg cacctgagcg catgccgccg
    15841 ctgctcgggg ctacctcgac cccatggacg cagaccggtt cgtggcacag ttcgatgatg
    15901 ccgtgcgcgc aggtcgcttc acccacgtcg tcacggggtt ggtgacaccg gcgtgacacc
    15961 tgaggtgctt ctgccgccgt gcaccgacgg ggagtctgcg tggacgggga cctgatgcga
    16021 cgggcatcgc ggggctgctc cggcgatgcc cgtcgtgcag atggacaagg tgccccggca
    16081 ggacccgcct gtgcagctcg tgccgatcaa tgccgtttcc tggctcgcat gccctggatg
    16141 tgcccttggg gcccgctcac cagagggcgc cctgctcggc tgacgggctg ggcgtcggag
    16201 gtgtcgcggc caggtgcacg cgcgtcttgg tgttgatggc acgaggttcc gtcgttacgg
    16261 cacccgagtt gcgtagctgt cggacggcat cgatcacctt gccgggctgg tagacggttt
    16321 ccaagagggc gtatcgcttg agttctggat ggttcgcccg tcgggagcta cggagatgaa
    16381 gtcgcgcagg atgcgtcgca gcggacccgt atcgggttcg aatacgagat tcagcatctg
    16441 ctgtcgggtg tccctggggt cgcggtagcg gacgccgcag gaaggggcca ccttccacat
    16501 cgcggctttc atcttctcca gtcccagccc gtgctgggct ggtcactcct cgcggcgggc
    16561 gatcacccgg aaggcgttgg agaagcggct gcggcggatc agcggggcga ggagccggtc
    16621 cagggcgtac atcgggaagc agaacggtat gcccgcccag aagaccgtct tggtgaccgc
    16681 ggcgccgaga cggcccgggg gccggggcag ccagggctcg tcgcggaacg gcagcagccg
    16741 cagcacgtac agccctacga gcgcggtgaa gtccacgggg atatgggact cctcgcggtc
    16801 cgtcgccacc accgtgaagc ccagctcggt gagggcccgg cgcaggttcc tcatggtcac
    16861 gaagtgctgg tgctgaggct ggaaccacgg cagccagtac cggccgaaga ggcggccgaa
    16921 gggcgactcc gggttgggta cctcgatgat caggtggccg ccggggcgga gcacggtgtg
    16981 caccgcggcc agttgggcct tcgggtccgt ggtgtgctcc aggcagtgga acatgctcac
    17041 cgcgtcgtac tggccggcga gttcgtccgc gaggtcgggc agaaagccct ggtaggcccg
    17101 ctcgatgcgc cccgactgct gcgccccgag cacatgggcg ccgatgtcga gcccgtcgaa
    17161 ggcggtgccg ggcagtgctt ccttggccgc caggcagaag tcaccgcccg ccgtgccgac
    17221 gtccagccag cgcttcggcc gggcatgccg ccgcatggcc gcggcccggt cgcggttgcg
    17281 tttcctcgcg gcgtcgctgt ccagggcgcc gccgatcttc tcggcgtaca ggccgtcgta
    17341 gaagtcccgg tagtagaagt ccagtccggc cgcgctgagc tgcgggttct ggaaggtgtg
    17401 tccgcagtcg cggcactggt ccagggtgaa ggtgccgggc tttcgctgca ggtggtcctt
    17461 ggtgcgcagg cggcgacgca gctgccgcgc gccgcaccag gggcagtcgg tgcggcgcgg
    17521 ctcgaagaac cgggcgatgc cgtcggccag ctctgcctgg tacgcggggc gcaggcgggc
    17581 gacgcgttcg gcgtcggaag cagggggcgg tggggcgggt gtgtcggggg tgtcaggggg
    17641 ctggttcgtg gtggccatgt ccgtggtctc ctctcgttcc actcttcggc acggcggtcg
    17701 ccctgccggt cggtcgctca ccgctcccgt gactcctgcg gctcccgtgg cttctgtgcc
    17761 gcgaacttct ccaggtacgc tgccgcggca gccgccccgc ccgccgcacg gaaggagtcc
    17821 ccgacgcgcc gggccgccgc gcggtaggcg ggcccgtcga gtacggcgtc gagggcggca
    17881 ccgatccgtc ggcggtcggc gcgcccgaag cgcacccgca ctccggcgcc ggcgccggtg
    17941 acctggccgg cgatcagtgg ctggtcgtcc cggatgggcg cgaccaccag cggtacgccg
    18001 tgccacaggc actcggcgac ggtgttctgc ccggcgtggc tgaccatcgc ggacgcccgg
    18061 cgcaggagcg gcaattgggg gatccggggc agcaccagga ggtcggcgtc ggactctccg
    18121 tcgagtaccc ccccggggtc ggcgagtacc gcctgcagcc gccgcccgcg ctcccgcgcg
    18181 gcggccgcgc actcggcgag gaaacgcgcc cccaggccgg tgttggcagt gccgagtgag
    18241 accaggacgg tggcccggtg ctcgtcgagc cactcccagg ggaagtcggc ggccgggcgc
    18301 cgggtgaacg ccggaccgac gtaccgcagc tgcggcagct gagggcccgg gcccgcgagt
    18361 tcgggggtgg tgaaggagag caccaggtcg ggggagaagc gcggatcgtg ggtgcacccc
    18421 gggtcgccga ggcgggcgcg cagctccgcg acgagcccgg cggtccactg agccaccttc
    18481 ggcatgccgt ccagggcgtc gctgaactcc gccggggtgg tcgacgcggt ggcgtacggc
    18541 accccgaggc gctcggcgac gagggcaccg gcgagggtct gctggtcggc gacgacgaca
    18601 tcgggccgga acccttcgac cgcgcggcgc acaccgggcg ccatcgcccc ggcgagcggc
    18661 acgaggaact cctcccacag gaagcgcaag gctgcggcac cgcgcagggc agcgggacgt
    18721 tccgggagcg tgggcacgtc gcacgggtac acctcggcgt cgggcccggc cagttccccg
    18781 acgaacccgg gcagtccggc ccaggcggcc cggtgcccgc atctggtcag ctcggcggcc
    18841 acgctgaccg ccgggttgac gtgcccgacc aggggcggca cgacgaacag aaagcggctc
    18901 acggcgcgac cagctcccgg tggccgtccc gtagccagtc gagcaccagc gggacgaccg
    18961 tctcgggggt gccgacgagc acggagtgcc cgtgcccggg caccgtcagg gtgcggcagc
    19021 ggggcagcag cgattccagc cagggcgccg tgtcggccag gtcggaggta gcgccgtaca
    19081 ccgcgcagac cggcacgtgc aggctctgcc aggactcctc ggcggggacg gggcaggacc
    19141 cgatgtcctc ggcgatggag gtgccgtgca gcagccgggt ggcccagcgc accaggcggg
    19201 cctcgtggcg gccgtaggtc tcctcgatcc acggcagggt gcgctcgtcg tggagctggt
    19261 gggcggagcc ggccaggatg ccgctcatct tcttggccca ggcggcggtc ggcggctcgg
    19321 actcgagcat caggatgccg gcgacccgct ccggtcggcg cagtgcgtag gcgagggcga
    19381 cggtgccgcc gaaggagttg ccgatcaggt ggacgggccc ttccagggct agggcgtcga
    19441 gtagcgcgtc caggtcgccg ctgaagtcct cgacgccgta gccgcgcggc gggcgggagc
    19501 tgcggccgtg gccgcgctgg tcgtacatca cgacgtcgtg tccggctgcg gcgagcgcgg
    19561 gcgcgatggt gaagtagtag ctggtcaggt tgtcggtggc gatgccgtgc acgaggacga
    19621 ccgtctgggg cgggcccggt gccggggtgg gtgcgccgct cagccgctcc acgttcagcc
    19681 ggatcccgcc cgcctcgatc gtggtcaccg caggcacccc gcgatgtact ggacgagttg
    19741 tccgacggtc agtccgatga tgtcggagag ttcgagcgag gcgaaccagg cggggaagtc
    19801 gacccggtcg ccgtagcgcc cgcccagctc ggcggtgagc gtgaccaggt cgatggactc
    19861 caggtcgagg tcctccacga agcgggtgtc gggggtgatc ggggtgtcgt ccagttcgag
    19921 gtcgtcgagg accgtgtgca gagcgtcggt gacctcggcg aggacggcgg cgtacgcggg
    19981 gccggtggtg gcggggctgg tcatgatggg ctctcctcgg tccaagcgac ggcgtaggta
    20041 cgggtgggca gccccggcgg gttggtcaca tcggcgagcc ggatgcgccg cagccggccg
    20101 gagggtgccc ggaccgtgag ggcgcgggcg ccgtcttcga attcgaccgc cgtgaagtcc
    20161 cgcggtcggc cgcccagtcc ggtgccctcg gccttggccg cggcttcctt ggcggcccag
    20221 aaccgggtca gccaaccggg gccgccgccg agcccggtga agggcgcccg ctcgtccggg
    20281 gcgaggatgg cgtcgtaggt cgtttcgggg cgctcgacga tctcctcgat gtcgatgccg
    20341 gtgccggtgc cggggctgtc ggcggcgggg tggacgagtg cgacggcggc ctcccggcag
    20401 tgcgccagcg acagttccag aggcgggagt tctctgccgt gtacgccctc ggggcgcggt
    20461 ctgccgccag ggtcgttggc gacccgtatc tcggcgggga agacggggcc ggcgccgtgc
    20521 gcccacaggt ggcggcgtac ggcgtccttg gcggcgatcc ggccgagcag ccactggcgc
    20581 cggccgcgcg gggggtgccc ggcgtactgc tcgcgctcag ggcccgcgag ctggctgcgc
    20641 atgtatatct cgcgggatgc ggggtcgggc cagcgttcga agaccagctg ccagccgccc
    20701 tcctgggttt ccgacagagt gttgtgctcg ggccgtcgtt tgaccggatc gacctcgggc
    20761 ggcgagtcga agcgccggtc ccgccagccg cggatctcgg cccagacctc gccgtcgcgg
    20821 gcgagctgcg cgtcagccac cagggcggtg tccgtcacgg tggtgaccct gatgtggcag
    20881 tcgagtgcgg tgccctgttc cgggggcggg ccgtggaaac ggatctcctc gacgcccgtc
    20941 gggaagacga tggtgcggtc ggggtgcgtg gccatcagcc agtagccgag cagctgaccg
    21001 acgttgtcga ggagcgcgcc gggcgcggac ggggtggtca ggacaccgcg gacgtgccgc
    21061 tcgccgagcg cgccgatctc ggtgacgccg cggaaccgcg gcccgtggaa catccagcgg
    21121 tcgtcgtaca tctgccgcgc cgacgcagcc ggacggcttt ccggggcgtc cgcccgccac
    21181 ggccgtgggc ggggcgcggt gtcgtgcccg tgggcggtct cgaccgtggc gcgggcgtgg
    21241 cgcccgaact ccacggcgta ccgcccctgt ccctcgggcc gggccgtgac cgtggcctcg
    21301 gtgggcgggg cggcgacggt ccactgcaga aaccgggcgt cgtgcacggc cacggccctc
    21361 cctgggccgg gcacggcgtc gatcatgtgc tgcaccaggg tggtggcggg caccacgggc
    21421 cagcggtcgg cgatctcggg ccagtgcgcg ggctgccgga agaaacagtg gtcggcgagg
    21481 tacggcatgg tgtcgagtga gatgcgcagg gtggtggcgc gggaggtggc ggcaggcggc
    21541 ggcaccgccc cggtcgccga gggctcgggg ggcggcgccg cgggcgcggt gcggcgcggg
    21601 gccgctgccg cggcgaacag ttccgccact tccgctgccg tgtccgccgt ctcgccgagc
    21661 agcgagcgca gttcggccgc cacggggctc cgcgcggcca cggccgcgag ccggtccagc
    21721 ccgggtgcgg gtgcctcacg cagggtgctg cggagccggt cccgggtggc ggcgtcgagc
    21781 gagacgagcc cggagccgag ggtgaggggg acggtgacgg gggcggggac ggctcgcggg
    21841 ctctccgtgg ccgtacggac ggtctccgcc gtagggccgg tctccgccgt gcgggcaggt
    21901 gccgccgtcg accgaggcgc ggcccccgcc cgcagcgccg cgaagtccgg ctcggcaccg
    21961 tgcgaccaga gtccggccgc cacccggtac agctgcgaaa gcccgctgtg ccggggcgtg
    22021 ttggcgctga gcgtcaggca cgcgcggctg gtgagggtgt cgtccacgag agccggcagc
    22081 tggccctggc ccagctgtac gaaggcccgg aacccggcgt cgtacagggc cgtggtgagc
    22141 tgccggaagc ggaccggttc gagcaggtgg cgcaggaaga gcgcgcgcgc cgcggcctcg
    22201 tcggtcggga agggcgcggc ggtcgtggcg gaccagacgg gcacccgggg cgggtgcagc
    22261 gtgaagccgc gcgcggcctt ctcgatggag gtgaggtacg gggcgagcat cggagtgtgg
    22321 aagccggact cgaagggcag cagccgaccg agcactcccg cgccgcgcag ccacccggtg
    22381 agcgcctcga cctggtcgtg aggcccgcag acgacggtct ggtggggcgc gttgtcgtgc
    22441 gagacgacga cgtccgggta cgccgcgagc tcggcatcca cctggtccgc accggtgccg
    22501 aacgcggcga aggcgagccc tgggacgcgc agcgtggccg ggtcgaagtc ccgcaggaag
    22561 gcgtcgacct cggcgtccgc gtacatcccg ccgaccgcca tcgccgtcca ttcccccaca
    22621 ctgtgcccgg ccagcgcgtc cggccggacg ccgatccggg cgagcgttcc ggcgagcagc
    22681 cggccgaggc cgacgacggc tgcgccgtgc cgggcgacgt cgcccacgcg ggcgtccggc
    22741 cagtgcggcg ccggcaggcc gaagtggcgg gcgacgtcct ttgcccgcgg ctcgaactcg
    22801 gcctccagcc ctgggcagag gaaggcgatc ttcccgccgc ccgtgccgag caccggccgc
    22861 ggcgcgcacc agacgtcgct ccggccgccc catgtccggg cgcgggcgac tgccttgcgg
    22921 gccagggcga ggcggcggtc ggtggggtcc aggacggcga cgcgggcgcc cccggctccc
    22981 ctcgctccgc cctcagcggc ggccgcgcgc agctcggtgt cgtcggcgtc gagcagttcg
    23041 gcgaggtcct gcggggtcgc ggcggcgagc cgcaacagcc ggggcggctc ggccacttcg
    23101 gcacggtccg cgcaggcagc aggcccagcg cccgggccgc cgggtgccgg ggccgcaggc
    23161 gcgacggccg gggtcgatgc cggtgcggga gccgacgccg gggcaggcgg ccatgcgggg
    23221 gcaggtacgg gctccggtac cgactccagg acgacgtggg cgttgatccc gccgaagccg
    23281 aaggcgctga ccgcggcacg tcggacgtcc ccgtcccagt gccgggcctg ctgggccgga
    23341 gcgaagcggg tgacgcggag cgccgggtgc gggtcgtcgc agtgcagggt cggcaggagc
    23401 gtgccgtggt gcaccgccag ggccgccttg acgaggcccg ccacacctgc cgccggcatc
    23461 gtgtggccga tcatcgactt cacggagccg atcacggcgt cgggcccggc gtccgggtcc
    23521 ggcggcccga acacctcggc cagcgcggcc agttcggccc ggtcgccgcc gggggttccg
    23581 gtgccgtgcg cctccaggag gccgagcgac cccggtgccg ccgggtcgag ccccgccgcc
    23641 gcccaggcga gccggacggc gcgggcctgg ccgccggggt ccgggttgac cagggagccg
    23701 gcccggccgt cgccggccac gccgacgccg cggacgacgg cgtagatccg gtcgccgtcg
    23761 cgccgcgcgt ccgcgagccg tttgagtacg accacgccgg tgccctcgcc catcagcacg
    23821 ccgtccgcgt cccggtggaa cgggcggatc cgctgggacg gcgacagcgc ccgcagccgg
    23881 ctgaagacgg accagagcgt gatgtcgtgg cagtggtgta cgccgcccgc gagcatcacg
    23941 tcgcagctgc ccgcggcgag cgcgccgacg gcctgatcga gtgcgacgag cgaggaggcg
    24001 caggccgcgt ccacggtgta ggcggggcca cgcagatcga gccggttggc gacccgggac
    24061 gccgcgaagt tgggcacgag gccgatcacc gactcggggc tctgctcccc gccgagcgcg
    24121 gccgtgaacg ccatccgtac cgcgtcgagc cgctcgccgt ccagctcggg cagtaactcg
    24181 tggagggtac gcaccagttg ggcggacgta cgcatccgct ggtcgagtcg ggcgagcccg
    24241 tcgctcagat aaccgccgcg gccgagcacg acaccgaccc gggagcggtc ttcgggcagt
    24301 gcggccttcc ccgcgtcggc gagcgcggcc gcggcggtgc gcagtgcgat cagctggtcg
    24361 ggttcggtgc cgggcacgga gtccggcatg agtccgaaga cggtcgggtc gaaggcggcg
    24421 agcgcgtcga gcccgtcgac gaagccgccg cggcggcagt agacgccatc gaggccgcgc
    24481 cgtccgtccg ggtcgtagta ggtgtccgcg tcccagcggg ccttgggcac ctcggagatg
    24541 gcgtcagcgc cggtgacgag gttgtgccag aacgcggcca ggtcacaggc gccgggcagg
    24601 gtcaccgcca tgccgacgat ggcgacgggc tgccggtgct gcggggcggt cggtcgcatc
    24661 gtggggctca ccggcccgac gccgtcagga cgacctcgtc ggtctccggc tcgccccagg
    24721 ccagctcccg cagcagcgcg agcacgcctt cctccgggtc gatcagctcg atgccgcggc
    24781 gcgcgtactc ccggcccagc tcagggccga ccatgccgcc gtgtgccccg gccggtgccc
    24841 acgggcccca gtgcacggtg acggtacggc tgccggtgtc ggcgcgccag aggcggccga
    24901 ggcgggcgag tgcgtcgttg gcggcggcgt agtcggcctg gccgcggttg ccgtacaccg
    24961 ccgcgacgga gccgaacatg acggtgaagg cgggcagttg gggaagtcgc cggagagccg
    25021 agagcagtgc gcgggcgccg tccaccttgg tgccgtagac ccgttcgaag gagacggggt
    25081 ccttctcggc gagcagccgg tcctcgatca ctccggcggc gtgtacgacc ccgtcgatcc
    25141 ggccgtacgt cgcgtacgtc tccttgaccg cctgctgcac ggcctccgcg tcccgcaggt
    25201 cgagtgcccg gtatctggcc cggccgcccg cgtcgtgtac ctcggccagg gtcgtggcga
    25261 tctcgcggcg ggccaggacg cggcccgctt cgcggtcgat ctcggcggtg ctcagaccgc
    25321 cccgggcggc gagcgctgca cgcagcgcgg gcaggtcggt ggcgtgggcc agctcgtggt
    25381 gcccgcccgt gccgtcgtcg agcggcgtac gcccgagcag ttcgacccgg cagcgtgcgg
    25441 cggcggcaag ggcgagggtg aaccgggctg tgatgccgcg tgcgccgccc gcgaggacga
    25501 cgaccgactc cgggccgagc ccgagtgccg cggctgcggc ggcgccggag gaggcgggcc
    25561 cggcgccgga ggagacgggc gggcccagag ggctctcgta cggtaccggg gcgcggcgga
    25621 cgccgcaggt gcgcagcacg acgggctccc ggtcgggcgc cagcagttcc ccgacgagtg
    25681 cctcggcctg ctcggtggcg ggctcgtcgg ggtcgagctc cacggtgcgg accacggtgt
    25741 cggggtattc gcgggccgcg gtgcgcacga agccgtcgag gccgctggtg tcgtcgggga
    25801 ggcgcgggca gagcagccgg cgcgggccgc gcagcagcag ttgctggagc acggtgagct
    25861 tggcgggcag cagttgctgt tccgtgcccg cgagagcgcc caggtgcagc actccgtcga
    25921 ccgggccggt gtgcccggcg agctgtgcgg tgtccgggcc gccacgggcg gcgagcgcgc
    25981 cgagtgtggt gagccgggtg acaagtgccc gtgcgagtgg cgtgtcgtcc gcgacgatca
    26041 ggaaccgctt cccgcgcagc tgtgccgcgc cttcggcgcc gggcacgggc ggcgggtcga
    26101 gcggggcggg ccgcagcaga tagcggtggg gagcctggcc ggtgagcggg gcgggggact
    26161 cctcggctac gggggccgag gtggcgaggg cgggtgccgg gtccgggtcg gcgagcgcct
    26221 tcgcgcgggc ccgcagccag tcggcgatcc cggcggcggt gcgctcccgg gtcagctcct
    26281 ccaggtccgc gtccggcaac gaccgcagat ccgcacccga gcccagcagc cgccgtccca
    26341 gctccccggc gatctccgtc cgcttgatcg aatccacact cagatccgcc tccagatccg
    26401 actccgcccc caccatctcc accggatatc ccgtacgttc agcgatcacc gccagcacct
    26461 cggccagcac atccaccccc accggagcgg gagcgggggc cggagccgca gcgagagcgg
    26521 ccggagccgg ggccggaagg ggttcgaggg ccggcggagc cgcctgcggc gcgggcggag
    26581 ccccgaagta gccgaggagc acgtcccgtt gtgcggccag catctcccgg ctgttgcgca
    26641 ggaactcccg gagcagttct tcccgttcgc ccatcgtcgt cgcctcactg gtccgctttt
    26701 cggtccgctg gatgcccgag atgcgccggg ccgggcgcag cgctcccggc accggccggc
    26761 cgtccgccgt gcgtacgagg tggccgtcga ccgtccagcc gggccgctcc ggcacggcgg
    26821 ccgggtcggc gagtgccgtg tcgcgtccgc tgaagagccg tgcgggcgcc accgggacac
    26881 cggccgcggc gagccgggcc agggcttcga ggtggccgcg caggcccgcg tcggggcggg
    26941 gttcgaacgg gacggcgacg tgcggccggt cgccgaggat ctggccgacc agaccggtga
    27001 gcacggtgcc gggcccgcac tcgacgaaga tccgcgcccc ggcgtcgtac atcgcctcga
    27061 tctggtcggc gaaacggacg ggggcggcga tctgctcggc gaggtcggct cgtatctggg
    27121 cggggtcccc ggcatagcgg gtgccggtga gattggccca gaccgggaac tcggggccgc
    27181 gcacggcgta cgccgtcagg atctcggcga agcgggacac ggccccggcg accagcgggc
    27241 tgtggaaggc gcaggcgacg ggcagcgggc ggacggcgaa cccggcgtcg gtgagcgcgt
    27301 cgacggcttc ggcggcggcg tccgtcgggc ccgagagcac gctctgcgcg ggcgcgttgt
    27361 ggttggcgac gacgacccgc tcggccaggc ctgccccggc gagcacccgg gtcacctgtt
    27421 cggcggaggc cacggcggcg gccatggtgc cgggatcgga cccctgtgcg ccggtcgcgg
    27481 cgaggatcgc ctcggcccgc tcccggctga ggtcaccgag cgtgtcgggg tcgagggcgc
    27541 ccgcggcgca gagcgcgacg agttcgccgt aggagtgccc tgcggccatg tcggggcgga
    27601 caccgaccgc ggtgagggtg tcgtacgcgg cgaggccgac cgccccgagc gcgggctggg
    27661 cgtggcgggt gtcggtgagc cgggcgacct gtgcggcgcg ttcggcggcg tcgaaggcgg
    27721 cgggcgggaa gagggcggcg gccggggcgt ggtacaggtg gcggccgagt tcggggaagg
    27781 cggtgaacag ctcggcgaac atgccggggc gctggctgcc ctggccgggg aagaggaacg
    27841 ccaccttgcc accgtcgttg ctttcgccgt cgccgtcggc cgccccggcg ggggcgcctg
    27901 tggccgggaa cactccgctt ctcccgggcg tgccgtcgag taggtcccgt atcaggtgcg
    27961 ggagttcggt gacggactcg gcgaccacgg caccgaggag cgggcccggt ccggtctccg
    28021 cgcgctgtgc ggcggtacgc gccaggtccc gcagccgcca gtggccgctc gccgcgaggg
    28081 cggcgagttc ctcggccgtt gcgcgggtgc ggaagacgaa cagctcggcg ggccagacgt
    28141 cgtggctctg gcgcggcggc gctccggcgt cggcgtgggc ccgcagcacc acatggaagt
    28201 tggtgccgcc gaatccgaag gcgctcaccc cggcgacgcg gcgggcggcg ggctcggccc
    28261 agggccgggc ctcgctgtgg aagacgaatg ggctgtcggg gccggtccag acggggttgg
    28321 gcacgtcgat gtgcagggtg ggcgggcgca ccccggtatg cagggcgagc gcggtcttga
    28381 tcagtccggc gagaccggcg gcgcacttgg tgtgcccgat ctgggacttg acggagccca
    28441 cgacgcagcc gccgggcgcg gccccggcgt cctcgaacag ccgggtgagc gtgccgagtt
    28501 cggtgcggtc gccgacgacg gtgccggtgc cgtgggcctc gatcaggccg acctcggcgg
    28561 gcgagacgcg ggcctgcgcg taggcgcgtt ccagggcggc gcgctggccc tcggggcggg
    28621 gcgcggtcag gccgagggag cggccgtcgc tggcgctgcc gacgccctcg atgacggcgt
    28681 agatccggtc gccgtcccgc tcggcgtcgg cgcggcgctt gagtacgaga caggcgacgc
    28741 cctcgccgag tgcgatgccg tcggcggccg cgtcgaacgt gcggcagcgg ccggtgggcg
    28801 acagcgcgtg cgcggaggag aagagcaggt agtcgttgat gccgttgtgc aggtcggcgc
    28861 cgccgcacag ggccacgtcg gcggcaccgc aggccagttc cttgcaggcg gcgtcgacgg
    28921 cggccaggga ggaggcgcag gcggcgtcga cggtgtagtt ggcgccgccg aggtcgagcc
    28981 ggttggcgat ccggccggcg atgacgttgg cgagcatgcc ggggaaggag tcctcggtga
    29041 gcttcgggag ctgctcctcc aggtcctcgg gaaggcggcc gacgtacgag ggcaggacgc
    29101 tgcgcagcgt cgcggcgccg gagatgtcgc tgcccgcctc ggcaccgaag acgacgcagg
    29161 tgcgctcgcg cgggaaggcc cggcggtcga gcccggcgtc ggcgagtgcc cgcctggccg
    29221 cctccagggc gaggagctgg acgggttcga tggcggccag ggaggcgggc gggattccgt
    29281 aggccagcgg gtcgaagggg atcggaggca ggaaaccgcc ccacttggac gcggacacgt
    29341 cgtccgcctc ggcgtccgcg ccgaagtgca gcgcgggatc ccagcgggtg tccgggacct
    29401 cggtgatcgc gtcggcgccg gcgagcacct gggcccagta ggcgggcagg tcggcggcgc
    29461 cggggaacat gccggccatg ccgacgacgg cgatgtcgag cggttcggga gtgggggccg
    29521 ggttccgcgc gggtaccgta ccgcccgcgt cgcggacgtc agcggcgagt tcggcggtgc
    29581 ggcgtccgta gaagtcggcg gccccgtcgg tgaccgcgtg gtgcagggcg gcgacggtgg
    29641 tgacggcgga gcggagcacg gcgacctcgc cggccatgaa catgcccgct tcgcgctggc
    29701 gctcctcgtc gacgtcgagt agctcgtcgc cgacccgctc gacgcccttg ctggcgatgc
    29761 gcaggcggcc gacgttgagc cgctccagct cctgccagac ctgccgctcg ggtatcccct
    29821 gagtccgcag ctcgtccttg acctcctggt acgtgtcgct gaacgcgctg ggcaggcagc
    29881 gggtggtgtg gccgggcgcg gtgtgcagga gcgtggtcga cctggcgtcc aaggccgcgc
    29941 gctggaacag cggccggatg gcgccgcact cgacggcctc ctcggtgaag aggtagccgg
    30001 tgcccatcag aacgccgacg gcggcaccgc gggtggtgag cggggcggcg agcgcggcga
    30061 ccatggcggc ggagcgctcg tcgtggatgc cgcccgcgaa cagcacctgt acgtcctgtg
    30121 ggtcggcggc gtcaccgcca tcggtgtgac cgtcgtcggc cgccgcgtcg aggaagtcct
    30181 ccaggacggc cagttgcgcc tcccagagcg ggaagctgtt gcgcggcccg atgtgcccgc
    30241 cgcactcggc gccctcgaag acgaagcgcc ggacgccggc cgccaggaac tggccgagca
    30301 gcccgggcga cggcacgtgc agaaaggtac ggatgccctc ggcctccaga gcggccgcct
    30361 gggagggacg gccgcccgcg atgacggcgt ggctggggcg cagctcacgg acggcctcca
    30421 gttgggcggt gcgtatctct tccggaacga agccgaggat gccgacgccc caggagcggt
    30481 cgccgagcgc ggacttggtc tgctcgagca gggtgcgggt ctgctcgggc ccggccaggg
    30541 cgagcgcgac gaacggcagt ccgccgccgt ccgcgacggc cgccgcgaac cgcgcctggt
    30601 cgctgacccg ggtcatcggg ccctggacga ccggcagcgc ggtgccgagc gcccggcaca
    30661 tcggcgagcc gccgcgcagc acggcgccgt cgtccgccac ggcggcgtcg atgccctccg
    30721 tgacggcggc gagggcgcgg tccacggtgc cgtaccgctc ggcgaaccgg gcggcgagaa
    30781 aggcatcctg gcccagcggc aggggccggt cgcgcaggac ggccgggagg ccggggcggc
    30841 tccggtcgag tacccggcag ccgtcgacga cgacggtctc ggtgccgtcg gcggcgcgca
    30901 gcagaccggc ggccgcgggg gccgtaccgg cctcgtcgag gagtgcgagc tggatgtcca
    30961 gtacgactcc tcgggcgccc gcgaggacgg cggcggccgc ggtgtgcggc ccgatgcccc
    31021 cgcaggccca cacgggcagg tcggccggta cggcgccgag tacgcgctgg agcagcacga
    31081 aggtggagtg ttcgccgcag gggtcgccgg actcctcgcc gcgcacgacg agcccggtga
    31141 caccgtcggc cacggcccgg acggcctcgt cggtgccgcg gacctcggcg agcacggcgg
    31201 ggtccgcggc ggcggcgcgg gcggcggccc ggaccccggc gacggtccag ggcgcgtcgg
    31261 gggcgaggag cacggtgcac ggtccggctg cggccgggtc cgcggtgcga cgcgttccgg
    31321 tgggcgccgg ggcccacagc tctccggggc gcagcgcaca gtcggcgggg acccgcacgc
    31381 cgtggctgcc gggggcccac tgccgcaaga gggccagggc ctcgcgggtg gcgcgggcgc
    31441 ccgggccgag gtcgaggaca ccggacccac cggcccggca gacggcggcg acgaggcggg
    31501 ggtccggtgc acccaacggg ctgacgccga taacggtgtg cgtcatgggg ggaggctcct
    31561 ctgtgcgatc gaggggggtg tgcgatcggg acgagcggat tcggcgcact ccgcgcgctt
    31621 tggagctgat gacccgtcag atactaatgg gtagtcagtt atctggctgc acccccgaca
    31681 ccgatcggtg aacaggaacc gcaacgagcc ggccccggtc gccgcagagc tcggccatgt
    31741 cgttgatgtc ggaaatcggc atgaccaccg gccgtgaccg cacgcctgtc cgcgcggcct
    31801 cttagccttg atccaccgat caatagccgg tccagagcct ggacatgagg gtgcggatgc
    31861 cctctaacgt gtacatgcga accggtgtgg gcaaaaccgc aggtagctga cctcgcctcc
    31921 tgcgttgcct gcccgcggcg cggtgttgat caagggctac ggggcgttcg ccttgcccat
    31981 ttacccgccc caccgcgggc ggtgaagccg ccctgggtcg ctgacctggg atgattggac
    32041 ttcttcaagg ttccatgtca cagatcgaga gaacacccgc gagagaccac ggacccctgc
    32101 cggggccgtg tccgattcgc tcctgcccgc cgccgtcctg gtcgcgttcg cggcaggcgc
    32161 ggatgaccgt gggggcccgt gcctgccgcg cttccgctgg gttgcatccg ctcgggttac
    32221 agcgggcagg tgatctggaa gacgaccgtg ttggggtcgt tgggggttgg gcagaggaac
    32281 tggtcgtagc gggtgtcgtt gtcgacgaag cgcttcagcc aggagacgct gtactgggcg
    32341 atcgtggtgt tcgggtcggt gaaggtgaag tggtcggtgt ccttgagcac gatgagtgac
    32401 ttgtcggggg cgctgaccag cccgttgtag aagggcaggg cgaagtcgtc gacggaggcg
    32461 acggtgtcac cgtcggcgcc gaagatcatg gtggggaccg tgatccggct ggagacgtcg
    32521 ctgaggtccc agggtgccag cgggatggcc gccttgagcg acggggtgct cgccgcgctc
    32581 tgcagcgagc cgccgcccat cgaccagccc atcagcgcca gccggccggg gtcgatccgg
    32641 ttcttcaccg tgctctgggc cgtcagatag gtgagtgcgg cgagttgctg cctactgcgg
    32701 tctgcgggaa agtcccacag cgcattggtg ttcagggtca tcaccacgaa gccctgggaa
    32761 gccagccggg gtcatcaact gctcgcctgc aaggtcgatt gagtgagtgt aaggctgatc
    32821 agggttgtta cgttcatggc gtgaatctga ccgagtgggc acgggtgcag ggcgttcatc
    32881 ctcagaccgc gtacaagtgg tttcgtgagg ggacgctgcc ggtgcctgct cagcgggtcg
    32941 ggccgcgcac gatcctggtg aacatcgcgg cgaatgcggc gcctgaggtt gtcggtggcg
    33001 tcgggttgta tgcccgtgtg tcctcgcatg accagaagcc tgatcttgag cggcagacgg
    33061 ccaggcttgt cgggtgggcg gccgaggccg gtcaccgcgt ggtgcgggtg gagtcagagg
    33121 tcggttccgg gatgaacggg gcccgctcga aggcccgtcg gttgctggcc gatccggacg
    33181 tgaccactgt ggtggtggag cacaaggacc ggctcggccg gatgaacgtg gagcttgttg
    33241 aggctgccct ggccgcggcc ggccgtcgcc tcgttgttct ggatgacggt gaagtcgaag
    33301 acgatctggt gcgggacatg gtggaggtgc tgacgtcgtt ctgtgcccgc ctgtacgggc
    33361 gcaggtcggc gaggaaccgg gcgaaggccg ctcttgaggc ggctgagcat ggctgaaccg
    33421 aagaagaagt tgcggcagat ttcgcggccg ttcgtcgccg acggccccac cggcgtgagt
    33481 atccgtgacc gtctcaaggg cctgaccggc gaggatgaga ggatcctgcg tctggtcagt
    33541 gagcacatgg gacggctggc gtcgctggat ctggcccgca ggtgccgtga cggactggag
    33601 cactccgcgg acacgtgggc ggcccgcaag cgggatctga ccgtcctgtc gtcgtcgcgg
    33661 tgggccggct cggtcacctc caatacccac gaccagtggg gcctttcccg gcgtgcccag
    33721 cacgcccacc tgcaatctct gggcgcaggg atcagcatgg tccggcaccg gctgtccctc
    33781 ccggtcgggg agaagggctc ccggggcaag ccgggcggct accggtcgaa acacgagtgg
    33841 tttacgaaga cgcgtcgtct ggcgatcctg gagggcgagt tcgaacgtgt caccgccgcc
    33901 cgggaggccg ggaaggtctc catcgtgcgg ggcggccgga agctgctcaa caaccggcac
    33961 aacctggccg ccgcgcacct gaccgccgaa cagtggcggg accgctggga cgctgcccgc
    34021 tggttcctca cggccgacgg agagtccggc aaacgcttgg ggaacgagac gatccgcgtc
    34081 accctcgacg gcgagatcag catcaaactc ccggccccgc tcgccgagta cgcgaacgcc
    34141 ccacgcggcc gctacgtcct ggccgcgaag gtgaccttcc cgcaccgggg cgacgaatgg
    34201 cgcgaccgga tcgagggcaa ccgggccgtc gcctaccgca tccactacga cgtggagcgc
    34261 ggacgctggt acctggacgc ctcctggacc cgcaaagaac ttccggtcgt ccccctggac
    34321 gcacttcggg ccggcggtgt gatcggcgtc gacatgaacg ccgaccacct cgccgcgtgg
    34381 cggctggaca cccacggaaa cccgaccggc aacccgcgcc gcttcgacta cgacctcacc
    34441 ggcaccgcac cccaccgcga cgcccagctc cgccacgccc tcacccggct cctgcactgg
    34501 gccaaggcca ccggcgctgc ggccatcgcg atcgaagacc tcgacttcac cgactccaca
    34561 acccgggaga aacacggccg caagaaacgg ttccggcagc tcatctccgg cgtccccacc
    34621 agcaaactcc gcgcacgcct gctgtcgatg tgcgcggaga ccgggatcgg cgtgatcgct
    34681 gtcgatcccg cctacaccag cctctggggc ggccagcact ggcaaaagcc cctgaccaca
    34741 ccgaagcgcc ccgtcacccg ccaccaggcg gcaggcgtgg cgatcgcgcg acgcgccctc
    34801 ggacaccgga tcaggcgacg gacggcaccg ccccgccagc accagagcga tgctggcggg
    34861 catcggaccg cccaggcccg acccggcgac cggaggcgtg agggaaaccg cccccgcgta
    34921 cccggaccac ggacacgatc cgacggagcc gaacgcggca ggaacgcggc aacccagaac
    34981 acccaaaacc gttcggggtg ttcggctgag tacgagttct ggcaacagga ctcactccca
    35041 ctcagtcggt aggaacggta cgccgatggc ttcctgggtc cagtggtgca gtccgcgtag
    35101 tgcgcggcgg gctgccgggt ggtgcgcgaa gaaacggtgg agacccggag ggaggaggta
    35161 gtcaggtttc agaagcaccc actgcggtgt gctctggaag acgtcgacat gggtcgcctt
    35221 cggctggatc tcgggcagga actgcacggt ggaagctccg gtgcccacca ctgcgacacg
    35281 ctgtccggtc aagtcgacct cgtggttcca acgggcggag tggaaggcgg tgccggggaa
    35341 ggtgtcaagg ccggggatgt caggatggcg tacctgcatg ctaatcgcgg cggcttgtgc
    35401 gaacatccgc aagcaggacg ccactgagac gtcgctccca cggcgcggcc tgcaccgcgc
    35461 cttcgcccgc gcgatgctgc gcaccgccgt cagcaaggtc catcaggacc tgaggatctg
    35521 gagcaccaaa ggctacgagc cccgacccct gcgtcacccc cgcctgctgc ggcccttgga
    35581 ggccctggcc cgcttctacc tgcgtacctc ggtacgggac cgcgccctgc ggcgggctct
    35641 tactcccgac taccgcttgg gcggccgccg cctgatcacc tccggcacct actccgccgc
    35701 cctcacccgg cccaacgtgc ggctgcatcc cacccgcgtg accgccgtgg agggctccga
    35761 cgtcatcggc gccgacggca cccgtactcg cgccgacatc atcgtcctgg cgaccggatt
    35821 ccgcatcggt gacctcccct tggcccccca actgcacggc atcgacggca cgttggccca
    35881 gacgtgggcc gacagccgtc gcgcctacct gggtaccagc gtcagcggat accccaaccc
    35941 tttcctgctc atcggcccga atctgcttac cgggaccacc gccgtcccca ccatcctcga
    36001 agcccaactc cgctccatca ccaccgccct caaccacctg cgtaccagca gggcgtccgc
    36061 actggatgtc aagcccgagg cagcccgcca gcaggccctg catgaggcgc tgcgcaacac
    36121 cgtctacaac accaccggtg gcaccgccta ctacttcggc ctcccgggca tcaacacctt
    36181 ctgctggcct tggtcgaccg ccgggctcgt caagcgcctg cactccttcg acccggacgt
    36241 ctacacctgg aggctgccac tcccgaccca ggccggcgcc gagcgggatg gtctgcccgc
    36301 ccaccggtcg ggctgacgct ggtgggcgtc acggtcgatg cgctcctagg tggccaccga
    36361 ggaatttcct cggcgaagcc ggtgaggaag tcggagttct tcagcacatc aagcagctcc
    36421 agggcgcccc aaccccgtac gacttcgtcc ttgagggccc gcaggccgct gggctcagcc
    36481 agaggctcca gcttcgggag gtggtccacg gctcgccctt gcgaggcgag atccctggct
    36541 tggcgcgggg cgcggaggcc cgggactggc ctgccgatgt ggtccgccgc ccggttaacg
    36601 gcaggccgtc cgcgctactg tccgagggcg tgtgtgaggg cttcgtcgag cagttcccgc
    36661 agggtcgagg acgttggtgc gacggcggtg gcgagcaggg ccgggccgcc ggccagtggt
    36721 gcgaggacgg cgcacccctc ccgggagcgt gggcggagca ggatggggct gcgccgcatg
    36781 ctcatctgcg ggtcgacgag caggagttgg ccgacggcac ggtgtccgtg caggatggcc
    36841 gggccgtccc agccgggctc cgggtccccg tacgccgttt gctggtcgag cagcggtctt
    36901 ccggcacggt ggacaaggag tcggctgacg aggtggccgg gatcctcgtt ggcccggccc
    36961 agaagctgtt cttcccgcag caacaggcgt gcagtggagg cgagttcgac cgtgcaggtc
    37021 tgccggaggt tgctgtcggc agcgctgatc agcggctggg gcagccagcg caggctggcg
    37081 tgttccccga cggtgagccg tacgtcgtag gtggccgggg cggtggtagg gccgcgcagg
    37141 gcgagtgtgg cggcggccgt cgtgacctcc agggcggccc ggtctccggc ggtgacgtcg
    37201 atggtgagcc ggtcgccgcc gagggggcgc tcatcgcgcc gatgatcccg accttggcgt
    37261 ggtttttgtc ggtgcgcagg cgtcggaggt ggaacgggcc gtcgctgagt agccgcggga
    37321 gcgtggtgac gcgtccgttg tggctggcgt ggatgcgggc tgtggcgcat accccgtgcg
    37381 ggtgcccggc gggttcctcg gtggcggagg gggctccggt caccgctgcc ccagcggctg
    37441 gccccggtga aggtggcggt gctgccgctg tccggtccgc gatgagttgt gcggtggggc
    37501 tcatgcggcc gccttgtggt gccactcggt gaggtgggcg gtgatccagt cggcgacgtc
    37561 gcggatgccg tcgtccgagg tgaggctggt gaagatgacg gggaggtcgc cgcgttgccg
    37621 tttggcgtcg gtggccatgg tggcgaggtc ggcgccgacg tgcggggcga ggtcggtttt
    37681 gttgatgagg aggaggtcgg cggtggtgat gccggggccg cccttgcggg ggatgtcgtc
    37741 gccgctggag acgtcgatga cgaagatctg ctggtcgacg aggcccttgg agaaggttgc
    37801 ggtgaggttg tcgccaccgg actcgatgag cacgaggtcg agggggcgga gggtctcttc
    37861 caggtgttcg acggcttcga ggttggcgga gatgtcgtcg cggatcgcgg tgtgcgggca
    37921 ggcgccggtc tccaccgcgg tgatccgttc gggtggcagt acggcctcgc gcaggaggta
    37981 ctcggcgtcc tcgcgggtgt agatgtcgtt ggtgacgacg gcgatggacc agccctcgcg
    38041 cagggtgcgg cacagcgcgg cgacgctggc ggtcttgccg gagccgacgg gcccgcccag
    38101 gccgactcgg agggctcggc gggtgccgtc ggcgcggagc ggttcggcgc tgtgggtgtg
    38161 gcgctgcggc atggtctcgg ggtggtcgag gtgcatgcag gactccaggt gggcagggag
    38221 gggtgtcagg aggcgaagag ccggacggtc caggcggcgt gctgttcgcc ggtgatgtcc
    38281 agcagtggtg aggacgccga cggcagggcg tcgacgccct cggcggtggc gcggtccgcg
    38341 gcccgggcgg cggccgtggc gacggcgtcg aggtcggtgc tgaggtgggc cagcaggctc
    38401 gaggcgtcga gcgggtcgag gctgagcagg cgcactgccg cggtggctgg gccgctggcg
    38461 ttctcgtatg cggcggcgta ggcggcgtcc agtggggtga gcccggcggc ccgggcggcc
    38521 aggcccagca cgatcggctg gtgggcgccc tggggacgtg cggcggccag ccgttccagg
    38581 tctttggagg ggaaggtggc acgagctgcg cgcatcatct gccggccgag tcggcgggcg
    38641 acggcgcgca gcgcgggggc gggggtgcgg gcgtctgctg cgtcgtcgag cagcagcggg
    38701 ttgactccgg cggcggctgc ggcggccagg ccggccgtgg tcaggccggt ggtgtgtaga
    38761 cggccgcggc agaatgtctg aaggctgtcg gtgtcgtgta cggcttggtg ggcgatggcg
    38821 gcctcgatgc cgccggagtg ggcgtggcct ccggcgggga agcggccgtc ggccagcagg
    38881 agcagggctg cacggctcat gggtgagcgg ctgcctttcg cagggtcgga agcgatgccg
    38941 agcgtcggcg ggcgcggcct gcccgcctcg ggtgcccggc cgcggagctg gtgctccggc
    39001 ggccgggcag agagcggctt ttagaacagg aagtaccgct gtgccagggg tacttcggtg
    39061 acgtaggagc gcggcaccgt cgcaccattg agttcggtgc gggtgtcagt cgtggtcgca
    39121 ccgccgatcg tgacctcgaa gctgttgtgg tcgacttcga ggctgtcggg cacggtgtcg
    39181 ttcagtttca tgtcggcctt cgtgacgtgc cgggtgctgg tgatgtccac gaagtccttg
    39241 tcgagaccga gacccggatt gctgctggtg ccgtctccgt tgagtttgtc ggccacgccc
    39301 agagcgacga agttcaccga gttgcgtccc ggggagcggc cggtggagcc ccagaccggg
    39361 cgcggctggt agggctgcgg cgtggggatc gaagcgttgg cgtcgccgac ctgtgcgtac
    39421 gcgagctggc cgcccttgag gagcatgtgc ggtttgacgc cgaagaactt cggctcccac
    39481 agcaccaggt cggcgagctt ccccgtctgc acggagccga cgtagccgtc gatgccatgc
    39541 gtgatcgccg ggttgatcgt gtacttggcg acgtaccggc gcgcccggaa gttgtcgttc
    39601 ggctgcttct gctggtcgtt gaaggagtgg ttggtgtcgt cggtgatcgg gcggaccttg
    39661 gcggcgtcga ggtcttcctt cagcggcccg tagcggctct tcatgacgtg cgcggtctgc
    39721 caggtacgcg tgatcatctc gccgatgcgg cccatcgcct gggcgtcgga ggacatcatg
    39781 gagatggcgc ccatgtcgtg caggaggtcc tccgcggcca tcgtggacgg cctgatccgg
    39841 gagtcggcga aggcaatgtc cgccggaata tccgggttga ggtgatggca cacgatcatc
    39901 atgtcgacgt gctccttgac ggtgttgacc gtcaaaggac gcgtcgggtt ggtcgaggcg
    39961 ggcagtacat tcggttcctt gaccagctcg atcatgtccg gcgcgtgacc gccgccggca
    40021 ccctcgacat ggaagacgtg gatggcgcgt gccttcttcg gcgtgaactt gcccccggcg
    40081 tcccggccgt cgccggtgaa ggcggcccgc gtgctctcca gaaaccctga ctcgttcagc
    40141 gagtcggcgt gcagagcgag ctggacaccg cgctcttcac acacgtccag ggcccggtcg
    40201 atcaccgcgg gcgtagcgcc ccagtcctcg tggatcttga ggccgcagac accggcgtcc
    40261 acctgtgcgt tgagctcgtg ctcgttcatc gtgctgccct tgccgagcag accgatattg
    40321 accgggaact catccagcgc ctcgaagacc cgcctgatgt gccacgcgcc cggggtcacg
    40381 gtggtggcct tactgccctc ggccggtccc gtgccgccgc cgatcagggt ggtcacaccc
    40441 gaggccagag cctcgtggat ctccccgggg cagatgaagt ggacatgggt gtccacacca
    40501 cccgcggtga ggattcgccc attgccggag atgacctcgg tgctcggccc gatgacgaag
    40561 ttcgtcggcg tcaccggcgg gacttgcttc gcgggcccac gatccggcat ctcgaagctc
    40621 gtgatcttgt ccatcgtctc ggggttgtat gccttgccga tggcggtgat ccggccgtcg
    40681 cggatgccga tgtcggcctt gaccacgccc caccagtcga ggatcagcgc gcccgtgatg
    40741 actgtgtcca ccggctcgtg gcccgtggcc gtgcccgtgc cgtccttccc gtcccgggcg
    40801 agatgcgaca tccccatcga ctcgcggatc accttgccgc cgccgaagac catctcattg
    40861 ccgctgtacg aaggaccgcc gctccagtcg gcctcgatct ccagcgtgag atcggtgtcg
    40921 gcgagacgga cccggtcccg cgtggtcggc ccgtacagcg tggtgtaatc cgcccgcgtc
    40981 agttcgttac tcggcttcgg cggtcggccc tccacgggct tcggcgcctg gctggggacc
    41041 tgtccctgcg gagtactcat cgcaccatgc cttcgcgtag tccctggatc ttggtcaggt
    41101 cgctggtgtt gccgccgccg gccgtgactg caccctggat ctgcaccagc tccacacagc
    41161 actcgtcgcc cggttcgaag cgcacggacg tgcccgcggc gatgttgagc cgtcggccct
    41221 tcgccgcctc gcagttccac agactgcggt catccgggac tgtctgaccg gcagggacct
    41281 cgatgctgac gaccttgagc cccgggttga cctcggcgaa gtgatagtgg gaggcgacct
    41341 gaataggacg gtccgactcg ttcttcacct tgatcttcgt cctgcccggc cccggcaaag
    41401 cggtggcatc cccctgcagg ctgacgccct gcgcgtcccc gtcgaggtgc acattgaagt
    41461 agatcgcgtc gtaccgggca gctgtgtcgt cctcgtcgca gcacacaggc gaggtgccgc
    41521 tgtcatcgca gtcgaccggg gagcctggct tgcggagcgg ctgggggtgc tcgaccttgc
    41581 ccggggagac ctcgctctcc tctgtgccct ccgggatggg gtcgtggatg gtgaccagct
    41641 tggtgccgtc cgggaaggtg gcctccacct ggacgttctt gatcatctcc gtaacgccgt
    41701 ccatcacctc gtcacgggtg aacaactgcc ggcccgagtc catgatgtcg ctgaccgtct
    41761 tgccgtcgcg cgccgcctca aagacgtgca cggtcagcag ggccatcact tcggggtagt
    41821 tcaggcgcag cccgcggtcg cggcgccttt gtgcaacgtc ggccgcgaca tggatcaaca
    41881 ggcgctcccg ctcatgcgga gtcaaatgca cgatgagcca cttctcttgg tcggacagtg
    41941 catgcggcca ggcatgccgg agatcacgaa caggttcccc caggccggca accgggcgcc
    42001 cttcgatcat cagcgggcaa gatcagctaa agcgaccaaa cagcagataa accacaccac
    42061 ctgatgaaac cgcgcaacat gacactcatc cggccctcga cgtgccgctc agtgagctgg
    42121 acgaggagcg gtcactggca gcagcggaga ccacagaccc caagccgact cgcccatcac
    42181 ggcccttgaa cctcggccat ggccttgagc tcggcgacca ttccatcgac atcctttccc
    42241 gcgtctgctc tgaggcagcc gggcgggtgg ttcgggtcga ctcgtccaac aggacggcgt
    42301 gcagctggcg ccaggccgtc gccccggagc ggcccacggt ctccgcgggg acatctcgat
    42361 cgcgccgctc gccttcgtgt gctgttgtgc tcggctggga tcaggttcgg ggtgttgcgt
    42421 gaaggggatt cagcatcccc gcctcgacgc ccacttcctg ctcctggacg aggcacagga
    42481 caccaatccc gtcgtcgaac agatcttcct cgcccatcgc gaccacgccc agctcgtcat
    42541 ggtcggtgac tccgcccagg ccatctacca atggcgcggc gccaaagaca tcatgaccgg
    42601 cttcgacggc acccagctgc ccctgtccca gtccttccgc ttcggacccg acctcgcagc
    42661 cgaagccaac cgctggctgc accttgccga cgccccgata tccgcctcac cggcaccccc
    42721 gccgtgctca cgtcgcccag ccggacgccg tgctctgccg caccaacgtc ggcgccatgg
    42781 cccaggtcat gatcctcatg gcggccggat accgggtcgc cctggccggg ggaggagaca
    42841 gcctgcaggc cctggccctc gcggcccgtg atctgaagga aggccgccgt acccaccacc
    42901 ccgaactcat ccttttcccc cactggggag acctgcagga ctacgccgcc cacgacccgg
    42961 ccggccgcga cctgcagccg ctggtcaacc tcgtcgacac ccacggcacc gataccatcc
    43021 tcgccgccgt cgcccgcctc gcccccgaac cgcacgccca ggtcaccgtc tccaccgccc
    43081 acaaggccaa gggacgcgaa tggtcccgcg tgctcatcgc agacgacttc gcccgccccg
    43141 agaacaacat ccctgaagag cccaccggca ccgtgacacc accacctgat ctcatcgacg
    43201 acgccgaagc ccgcttggcc tacgcagccg tcacccgcac ccgccaacgc ctcgacctcg
    43261 gtggcctgtc ctggatccac gaccaccctg acggcggcgc cccgcccctc tagggcgttt
    43321 cgtttggatc aatgggtggg ccggaggagg atgccttcga tgtgcagtga ggctgtacct
    43381 ggccggtcga gcgggggagg agtcgtgcga tgagttttcc cctcgctcgg gtctgcatgg
    43441 tcagctgcct ccgtcacgag gagagagtca tgttgttggc tgacaggacg gcaatcgtcc
    43501 atggcggttc tggagcggtg ggggcagcca tcgcccgcgg cttcgcgcgt gagggcgccg
    43561 ttgtccatct cacgggaagg acggttccgc cgctcgaaga cgtcgcgcgg cgcattcggg
    43621 acgacggtgg ggctgcgcat gtcgctgggc tggatgcgac ggaccgcgac gccgttgatc
    43681 gccacgccga catggtggct gcgcagggcg gcggaatcga tatctgcttc aacgccacgt
    43741 ccaacgacga cctgcagggg atcccgctcc tcgacatggc cgtggcggat gtgctccgcc
    43801 cggtcacgaa ggcggtgacg accaccctca ccacagctac ggcagcggcg cggcacatgg
    43861 tccgaggagg cagcggcgtc atcctggtca tgggcggcgg gcgcgaggcc atctccaacc
    43921 tgggcggttc acacatcgcc tggtccgccc ttgccggtgt ctgccggcag cttgcatcag
    43981 agctcggccc gcagggcgtg cgcgtcgcct ggctgctctc acccggttct cctgcgcctg
    44041 gtgaggagga ccgggccgct gaaggagcgc tgctgaccaa gcgtccgcgc tacgacgatg
    44101 tcgccaacgc cgcggtcttc gccgcatccg actgggcccg aacgatgaca gcctttgagc
    44161 tcaacctcac cggcggcctc gtggtcgact aggctgcttc ttctggatca ccgagcgggc
    44221 cggatgaaga tgcggtggag cagggcgaag gtctgctcga cgacgtaacg gagtttgccc
    44281 aggcccttga tgttcggggc gcccttgcgg gagatgaccg gcaggatcct gcgcttgtgc
    44341 agctcctggc ggttggggtt ggagtcgtag cccttgtcgc cgagtagcga gttggggcgg
    44401 cggcgtggcc ggccgggccg tccggccaca ggcgggatgc cgtggaccag agcgagggtc
    44461 tggatgacgt cgttgacgtt ggccgcggtg acgaccttga gcggagtgcc gcgtccgtcg
    44521 cagatcaagt gatgcttgct gcccgtcttc cgccggtcta ccggtgacgg accggtgtcg
    44581 gctccccccc ttttttgcat ggatgtggga gccgtccaca cacgcgcggg atcagtcgag
    44641 ttcgccggcc gcgttcaact cggcgagcag aacgcggtgc atctgctcga agacgccggc
    44701 ctgctgccag cgatccaggc ggcgccagca ggtctgcccc gagccgaacc ccagctccgg
    44761 tggcaggagt tgccaggcta tgtcgttgtg gagctcgtac agaatgcctt gcagacacag
    44821 ccggtccgcc accggccgcg gacctggcgc cttctccggc cacggcggca gcaacggctc
    44881 gatcagcacc cacaattcgt cgtccacgat ccacggccga gtactcacac atgacgaatg
    44941 gccgcatcat cacaccagtc acggcccacc acgacacttc agcaagatcg tgttacgagc
    45001 tctacggctc cgtccgccac tacatcagct acgcacgatg ccgaaggcgc ctggcatcag
    45061 gagatcacca ggacactgga aatgaagcag ccgcgtatct gtggtgaagc tagggcaaat
    45121 gagcgtcgcg gtttcgacga tatcgtcctg gcgcgtaatc gatcctcaga gcgattgggt
    45181 cttgaccttc aatcttcagt gaggcttcag tgatgcgcgc acctacgcgt gttgcgtgtc
    45241 atctgaaggg aactgtcatg cagcagtacc gaaagagacg ctggtttgtg atcgcagcga
    45301 cagccgcgac attcgctgcg ttcgctggtg cggcaccggc tggcgccgta accgacagcc
    45361 agggaagtaa gagtggagcc gctgttgttt cggaattaac ccctctcatc ccggaaacta
    45421 caccgggctc cgacgaaccc gcgagggaaa acgacacgag ccgactctcg gccacgggcg
    45481 agatctgcac agcgcccgat gagaacggcc ggggttcgtg cattgagtac aagaatcccg
    45541 acaccatacc gggcctgccc agcggcgaag ccaattcgaa actcgcggca gttgccccgc
    45601 ctcaatggtg cgaggacgcc cagggagtcg tgtatgccac gcgcactcaa gcctgccgca
    45661 tcgacggggt cctctacgag acgtatgtcg tgcgcaacgg cgtccggact actacaggtg
    45721 aggtcaatct cctcctcatc aactacagct acggcagcac cagcgagtcc cgcatagccc
    45781 atcagctcga cgtcacggca ttcaatggct ggggcgacgc gctcaagggc tcctacagcg
    45841 gcaacgcgcg agtcggctac tcctgcacca agtagagcgg ttcgttcccc gcaaagccga
    45901 tccagccgct gagccaatgg cacacaggcg aggcgttctt cgactcgacg gcaactgccg
    45961 ccggcgccgt cggtgagtgc ggcacagggt ggaacctgac tttcacgaac ccgggctata
    46021 cctcgtcgac gtacgtcgcc cccgtcttcc gccagttccg gtgcgacaac aacaccgccg
    46081 gcaggaccgg ccccggctgc gtggtgcctt ggtatgcctc ggccgtctac tacagccgtg
    46141 ccgccaaccc tgaactggcc tcgcacgtct cccgtgccca agcctccggt ctgcccggtg
    46201 cgaccttcga ggctcctctg actcgcacca cggatccggc cgtcaaccag gacaaccgtg
    46261 acaaagcatg cggtgacgcg cccagcgtga ccggcaaatc atgcgacgag taccctgtcg
    46321 ccagttccta ccagggcctc tcagccggcg gcacacgccg caccttcgat ggatgcgggt
    46381 tccctggtat cccggccggg cagggcccca caggggtcag cgtttgcatg atcaacgcca
    46441 cggagaacag ctcacagggc ggactccact cggccatgta ccggtctgaa cgggtccttg
    46501 acaaggaccc gttccgtgtc gaggtgatcc cctaactccg caggcggaac atcatgtgac
    46561 gcacccaggg cgccgggagc ggagcgggtc tatcccggcc gtcccggcgc cacatacggg
    46621 cacaaccggc ttcggcgaag ctagcctgaa gcgggaggag gatccatgaa cgccctatgg
    46681 cacgacgtct tcgtatcgga aggcaccttc gggctgctcg atagcggaga gatccccatc
    46741 cactccgctg actggtccaa cggcctggtc gcgccgatgc tgcaaggcgg tgccctagtt
    46801 cgcacaggta tccagacggg atacgtccgc gtatgtgccc gcacccaggg ggaaccagcc
    46861 ggggacatcg acgaatcacg cccctgggaa gagatcgtag aggcgagcgt caccgctccc
    46921 cacaatcttc tccggctcga atcactcgac tacgggccct ctgccccaga cactttcctg
    46981 acaactgcgg acagtcccca gtaccgcgtc cgagtccacg ccctaggaag agacgtcgcc
    47041 cggagcaaga ccactcaggt acccccggag gagtatctgc tgctggtatg gccctccgag
    47101 ccggctccca ctcacagcct gcgcacgagt agccgcctcg aagaggagaa acaagccgag
    47161 gctgccagtc cccatcctcc acgcatggcg ccagccgaac cgcctgaggc gacagcggag
    47221 cgagagatcc gtgcccaact caacgacgca ctgcgtagga tccacaagaa gcagtagcgg
    47281 tgtacgaggc ggcttcgccc agactgcccc gggccccgtc gtccgctccc gaacgtcata
    47341 cgttcatccc caatctctgc tcgacaagcg cctccctccg cgtaaatggg cagcagcgcg
    47401 tcagcgccga cttcaccgct gagcgagcga cttccgcgcc caccccggca gcaacgccac
    47461 cgcgttcgcc ctctactact cgactgccta caacgcctgg gtgttcaacc gaaccgacca
    47521 ggacaaggcc agcccgctgt tcatccgctc cacggccgat cagaaacctc agttgaaggt
    47581 ctggacgcac ctggccggcg tgttcaaaac cgaaggcgat gacggccttc cggacactga
    47641 tccgaccaac gacaccattc atggatgttc ctcaaccacc cccggccgcg gcggccgacc
    47701 tggtcccggg agacggcgta gtggccggtg accagcttgg tcgcggtcgt gatcgcggcc
    47761 agtgcgagtg cggctggcag gagcggcagg aggtcgtcgg ggctgacggt caggccgatg
    47821 gcgaggaaga acacggcggc gaacaggtcc cgcagtgggc tgagcacggc tcgggcccgg
    47881 tcggctgttt cgccggtgag ggtgagtccg acaaggaagg ctccgactgg cgcggaggcg
    47941 tggatgagtt cggccagcgc ggcgacgatc agggtcaggc cgaggatttc agcatgagtt
    48001 gttcggcgtc ggggtgggcg agcagtcggc cgaggtggtg gccccaccgg tcggaggcgg
    48061 tgaatgcggc gaggaccgcg ccgacagcga tcaggacgcc gaggacggcc tgccaccagg
    48121 ggccgccgga ggcgaggacg gccagcaggg gcaggtggga ggccatggcg aagtcctcca
    48181 tgaccagcac ggacaggatg gccggtgtct cgcggttgct cagacggcga aggtcggcca
    48241 ggagccgggc gacgatgccc gaggaggaga tgtacgtggc gtcggccagg gccaggatgc
    48301 cgatgccgtc caggccgagg agccacccgg ccaccgcacc cggcacggcg ttcagcacca
    48361 agtcgaccat ggcggagggc acgtgccgcc gcaggctggc ggtgaactcg gtgagggaga
    48421 acttgcaggc cgagtgtgag caagagcagg acgactccga tgcccgctcc gatctccacg
    48481 aactctccgg ccgcgggcac gggggcgatg cctccctcac cgatggccag accggcgagc
    48541 agggacgggg gagagggtga agcgccgcgc gactgcacag agcacactga gggcggcaag
    48601 gatgatcccg agctcgagca gcagggtggc gggcgtgcgc acgctcagcc ctggacgatc
    48661 tgttccacgc cggtgattcc ctcgtgggtt ccgatcacga ccaggacatc accggcctgg
    48721 agtacgtggt ccggcgtcgg tgatgcgatc acgtcctcgc cgcggacgat cgccacgatc
    48781 gaggctcctg tccggctgcg cgcccgggtc tggccgagag gctgatcggc gaacgggctg
    48841 ctggtgcgca cctcgacctg ccccgacacc agcccgggca cctccttggt gaggtcggcg
    48901 aaccgttcgg tgatgcgcgg cgctcccagg atctcggcga ccgtgtcggc ttcctcgttg
    48961 ttgagccgga ccacgggccg tgcctcgtcg gggtcaccgc ccgcgtagac gaccaggtcg
    49021 aaatcgcccg tccatgcggc gacgatgccg acccggtcgc cctcatggtt ggtgaactcg
    49081 taccccagcc cgagagggtg agagatcagg catgtcggca aggcacaccc ctgctgacca
    49141 cgcccttgcc gcacagaagt gcaccaccgc tcgccctccg gcggggacac cgtgctccgg
    49201 cggcgacgca cggctgctca tcgccatgcc cccagccgag cctgtgggcg aggcaagtgt
    49261 ggcggccctg aggcgctggg ccgccagacg cccctgccgc gggcggaaac tgaaggtccg
    49321 ccagaatcgt cgccgcgcac gaccagacgc gccctgaccg agccccgtac gcccaccatc
    49381 ttgaccactc acacaggggg cccctggccg caggtctgtc ccggcttacg gcttgatgtc
    49441 gtacaggacg ttgaaagggt cgtccgccgt ggagcgggcc acgtcgcgga agcctgcctc
    49501 ggcgcacaga ctgcgtacga ccgcctcggg cataccgcat gtgccgaggg cggctccgtc
    49561 gttcgcgagg gacgtggtca tgcagtagaa catgctgaac ccgtagaaca tcgtggcaac
    49621 ggggccgacg ttgtcctcgg gacggtccgc gcagttgatc tcgagcatca ggtagtcgcc
    49681 gtcgtccttg accgccgccc tgatggcgga gagaagctgc ttgggttcag ccgcgtcgtg
    49741 gatgacgtcg aaggtggtga tgaggtcgta gcgcccggga agtccctggg tggcatcgat
    49801 cgtctcgaag gtgacgcggt cggcgacacc ggccttctcc gcgttctggc gggcgcgttc
    49861 cacctgggcg gggaagttgt cgaacccggt gaaacgcgag tggggaaacg ccttggcgag
    49921 cacgatcaga gcgcgccccg cgccgcatcc cacgtccgcg acgtcgatgc cccgttgcag
    49981 cctctcgacg acgtggggaa aggtgctcag ccagtcgtct accatcacgc tctcgaacca
    50041 gctgccggtg aagcggctca tgccgtccca caggatgtcc gggtactcgc tctgcggtac
    50101 gcctcctccg ccccggaacg cctcgcacaa tctttcgtaa ggcgtcaggg cggcgggcat
    50161 catctggtag acgccgccga ggaacatggg ccccgattcg tcggccaggg cgggggcgtg
    50221 ctcggcgggt aggatgaagc gcccgggctc cggttcctcc agatagcccg cgccggtcag
    50281 ccctcgcagc cactcgcgta cgtaacgctc attcaggtcc agacggtccg caagctcccg
    50341 gctgcccgcg gggccactgg tggcgaggcc tttgaacagg cccagtcggt cgcccaggtg
    50401 gcacagaccg atggtcatcg tcccgctgag gtccccgagc gccttctcca tgaaggcttc
    50461 gacctttgcc tcgtccaact cgcgtggtgc cgccatgatg tccttcctgg ccgtcgagca
    50521 cgatcgcgca gagcgaccgg cccggcaagc caaacaccgg gctgctccct cgtccgtccg
    50581 ccacgacggg cgggggtgcg aactccaccc ccgcgggcgg cgccggcgaa cggcccccgc
    50641 gcccatgcga aggcgcggca tccgcacggg tacttcatcg gagagttgcg agcggagtac
    50701 gacgctgttc ccgacccgct gggcgacccg gcggagtcca cgcccgcgca cgaactcctc
    50761 ctgacccggg acgcaagggg gtgtacgacc ggcagttcat caacaaccag cacatcgcgt
    50821 acctgttacg ggtgtagcca gctgtgggag gagtggtagg tgccgggtga agcagtaacg
    50881 acccgttctg aggcggagtg acatcccggt ttcagtgaat ctgcacatcg actgcgcaac
    50941 cgcggcgcag ggctcgatgg atctgcacaa gtgtctgccg catggtgctc cgttggtgcg
    51001 gagtgtcccg ttcgtgaacg tcgtggcaat accggtcggg tcccgatccc gcgcggcatg
    51061 tggagaggct gtccccaagg cgtgtgcaca tttgcacgga tgagtggcct gctcgttcaa
    51121 catctcgggt gtgtacgccg gtcggttgga tgcccggcgt gctccgtgct ttgatccctt
    51181 gcgccgcggg gcctgcacga aagtctccgg aaacgggggc cgcatgtgtc tctgcggccg
    51241 aggcccgcta tctgtcccca gcggggccgc cccccttgtg gatgatccat acgaagggaa
    51301 gtttcctcat gaactccgct ccccaggttg agactgtcga gatcgccgac gccgagctcg
    51361 acaacgtctc cggcggcctg cacgccaacg tctgcgccgg ccccacggcc gtcagcgacg
    51421 ctgacctcct ggcccaggtc gacgccgtca agaaccaggt cctgggcgcc gccgcccagt
    51481 acaaccacgt cagcgtcagc gcctccctct gatcggcagc ctgagcgcca gtcagtgagc
    51541 cccgcccaac ctgacggtgg ttgggctgtt gacggacgca ggctgtaagg aaccgcgaag
    51601 ctcctggcaa gaacgggctc ccctagatcg cccgtgtctg ccaggagctt cgcgtgcttg
    51661 tgtcctccga tcttcggtga tctgtccagc cccaccgtgc tgcctgaagg gcaccacgca
    51721 tcgcactgca cgagaacgca cgcggggaga gcgccagtcg gccgtgaggc ccgcagctgc
    51781 cggggccggg tcgggtcagg gggtacccga gtgatgaggt gcacgacgat ctgtgagcgg
    51841 agaggtttga gggggctgtg acacctctgt gaggtctggg cttgttccct gtgggggcgt
    51901 gggggcgtgg gggcgtgggg gcgtggggac cagcctgtcg atccccctgc ggtgcgggtg
    51961 cgtctacgct cgctgcgcac tcggtacgaa cgaggatggt gttgggtatt cgagggcaac
    52021 tccgcctgca ggcgtacgac ggggagttgg gcgcggccgt cgcgcgggct caggaaggtg
    52081 acgaggttgc cttcgcggtc gtgcaccggc gggtgcagcc cgggctgctc ggatatctgc
    52141 gtggactggt cggggacgac gccgaggacg tggcgtccga cgcctggctg gagatcgccc
    52201 gggacctggg gcggttcaag ggagacgggg ccggcttccg cggctggacc gcaaccatcg
    52261 cccggcaccg ggcctacgac catctgcgcc gccagaaggt acggccacgg ttggcgctcg
    52321 agcacgacgc gctcgatctg ccccgcccgc accacacccg cgaccatgcc ccggatccca
    52381 tctccaccga ggccgccctt caactggtcc gcgggctgcc gcgcgaccag gccgaggccg
    52441 tgctgttgcg cgtcgtcgtc ggcctcgacg agcccgtcgc cgcccgcgtc ctcggcaagc
    52501 gccccggtgc ggtgcgcgcc gccgggtgcc gggggctgaa acgccttgcc cgccggctcg
    52561 gcggcggagg agtggcacac gaggttcccc ggacgctggg ggaatcgaca tgaacggcaa
    52621 cggcggccga ccgtcggaca gggatggatg cgggcatggg tgagccgcac agcgacggca
    52681 gtgccccggg ccgccggcgc gtgcaccgca gcgatgccgt gtccggcccg gagggctccg
    52741 cactggaggc gcttctcgcc gcgctgcccg aggccggtgc cgacagaaag ggtgagcagc
    52801 aggcggtggc cgcgttccgg gccgcccggg acgtcggggc acaccgggtg cgaactcggc
    52861 gccgggacga ctggcggccg cgcgggcagc ggcgggcatg gcactcggtg cgggccgccg
    52921 tcgcgctgtc cctggccagc ctcaccctga gcggcgtcgc gttggcggcg atcggcgtag
    52981 tccgctcgtc ggacgacggc cacggggacc ggcggcggtc gcagccatcg gccactgcct
    53041 ccagccaggc cggcgcgggg acgcctgcgg ccgagtccca cacccccggc gcctccgccg
    53101 cgctcgatca ccaggccacc gctcaggaca ccgacgccca ctgccgggcc tatgaggctg
    53161 tcaaaggccg gggcaaggcg ctggacgcga cggcctggcg gcggctcgtc gaggccgcgg
    53221 gcggcacgag ggacgtcgct gcgtactgtg ctgagcagtt gacgcacacc gcaggagacg
    53281 agcagggcag ggccgagaag accgagaacg ccaagaaggc cgagaaggct gccaagccga
    53341 ccaagcccgc taaaacgacc aagcccgaga agcccgagaa acggtaaccg cctccacact
    53401 gcggtatggc ccatggcccg gctgcgatct cacgtgtgac acatcagatc cgtggttcgc
    53461 tgtaggaggc gacccgatca agagggtcaa ggggcccgcc ctctgtggag ggggcagcgg
    53521 gctccgacgt gtggggcagg ctcgattacc cccgtgacgg gtctgccctg ctcgaagatg
    53581 aaggccggcc ctgggggccc aaccgcgctg cggcatccag ggccttctta gtgggcgggg
    53641 tggcagagcc gcacttcagt ttgcggcagc cgtgccgagt ggcgtacgcg tgggcgacgg
    53701 tgacgcctgt tcatcgattc acgcgcccgt ggtgccgtcg ggttcgggtc agcggcccca
    53761 actgcggagg cgcggacagg tgagtgtctt gacatggatg ccggacctgt caggggcggg
    53821 tatcagcagg actcttcgaa cttcaccgcg ttgagcgtca ccggctggcc ttcgagcctg
    53881 gtgccggcgg cgggttcttg ggaacagacc ttccagttgg actcgatgat gatgacgcgg
    53941 ccttcgccca aggcgtcgtt gacggtgatg ctggtgatgg gggcgagggc ctctcgggcg
    54001 accttgacgg acttgccctt gaagtccggc atcgtcgatc cgggggtctc cgtcgcggcg
    54061 ccttggtccg tggccgggca ggtcccttcg agtttgacgg tggcgaagtc gacctgggta
    54121 ctggtggggt gcgcgccggc tttgggggtc tggaagcaga ctttccagtt gcggtccagg
    54181 gcctggttgc ggccgcggcc gagagcgtcg tgcgaggtca ggttgtagaa ccctgcttct
    54241 tgtgcctggt cctgtgcaaa ctgcagccct ttaccgatca tgttcggaag ggagccggtc
    54301 tcggccctgg tcgtggtgtc ctgcgtagcc gtgggctggt cggtgggggt gctttgccgg
    54361 ggggtcgcgg gcttgtcggc tggagtgccg ttcgtggggc cgttgccgcc gcaggcggtg
    54421 aggccggtca gcgcggcgag caaggcagcg gcgagtgcgg tgcgtgcgtg gctgtgcatg
    54481 atcccctctg gggtcgtgcg ttggcgaggg actgacatgc atggtctgcg ggatttatgg
    54541 atcatatatg caaaactctg gcaaattgtc taatttgcgc aatagcttgc tgcccagagg
    54601 gtgcgcgcac accaagggat ctaacgctgg cggagtcgtc tcctgcttcg ttcttgtcga
    54661 tgtcggggcc acccgagggg ggcatctgct ccttcaggta atcacctcgc gtcccagccg
    54721 attcgctccg cgatcaccgt cgccggcatg gtcgatgtct cccggagaaa ctcatcggcc
    54781 agttgcggtc tgcggatctc cgtccagccc tgcgcacatg tcacctcctc ccctttccgt
    54841 ccttggtcgc cgtggccaga gtcagacgaa gatcaccaag tgggacagtg tttgatccgc
    54901 gccggcagag gggcatggtt cgctgtcgtc gagagatgtg gttgtgacgc ttcgaaggtc
    54961 ctgtgcgctg agaggagtgg attcgctgcc ctgctgttgt gcccctgagc gggcgggcgt
    55021 cgcggttggt gtggtggttt ttcagggacg tggtgccgta gtgctggttg cgcagcgata
    55081 tcgcctcgac gggcgcatcg gccgaggcgg catgggcgag gtgtggcgcg ccactgacga
    55141 gttgctgggc cggacggtgg ccgtcaagct gctcgccgcc gaggcggacg aggccgcgac
    55201 gcggcgtttc cgccgcgagg cggaaatcgc cgctcgcgtc actgatcccc atgtggtcgc
    55261 cctgtatgac gccggcgccc acgagggacg gctcttcctg gtgatggagt tcgtcgacgg
    55321 cgggagcctg gccggggagc tggccgtcca tggcgtactg ggccccgagc gggtcgcctg
    55381 cctcgcggcg caaatcgcgg agggcctgtc cgtcgcgcac cggcaaggcg tcatccaccg
    55441 cgacatcaag cccgccaatc tgctgctgac ctcggacggc acagtgaaga tcgccgactt
    55501 cggggtggcc cggatcgctc acgagacggc ggtggcgctg accgcctccg ggcagctcct
    55561 gggtacgagc ccctacctgg cccccgagcg tgccgtgggg cgcccggccg ggccggcctc
    55621 ggatgtgtac tcgctgggct gtgtcctgta cgagctgctc accggccact cgcccttttg
    55681 gggggaaact gccgcagccg tcgtccacca gcacgtcgag gccgtgcccg cccggcccgg
    55741 acagctgcgg tcagggctgc ccggcagttt cgaggactat ctgctgcggc tgctggcgaa
    55801 gaacccgggt caccggccca ccgccgaacg cgtcgccgac tggttcaccg cctggcagaa
    55861 cacccgaccg cccgctgcat cgcgtctcgc atcaccggac acccaggcgc acaccgcacg
    55921 gttctccgcg gccccggcat cgcggacgcc ccggagacga cgccccaccg gacggcgcac
    55981 cgccgcactc ctcggactgg gcgcggtcgc tctgttcggc gcctcggtcc tcatcggcgc
    56041 gactctgggc gacaacgaga ctcggggccc gtccgggagc accgctccct ctccgtccct
    56101 gtccccctct ccatcggcga ccacagcggc caccgatccc tcgactccgc aggagacccg
    56161 agtcgccacc acggcccctc cgccccccgt accttccgcg acgccgaccg cgcacgacac
    56221 cacgactgcg gccaccccca cggcaccccc gagcagcacc gcggcaacca cgccctcgcc
    56281 gtcctcgacg ccgcccaaga agaaggccga caagcacaag ccgaaacggt gacctcgggt
    56341 aggtcccctc catgggcgtg cccgccgtcg tgaacggtca ccgccagcag aggctgggcg
    56401 tgctggcctt cgccgtcgtc agcgccagca cgacgagcgt gaacacgccc cgtggccagc
    56461 agccgcggct ttttcctccc gcgccgagcg gccgggcaag ccggtctgcg cc
//
