LOCUS       NZ_BNBM01000008        47899 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces lanatus strain JCM 4588 sequence08, whole genome
            shotgun sequence.
ACCESSION   NZ_BNBM01000008
VERSION     NZ_BNBM01000008.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces lanatus
  ORGANISM  Streptomyces lanatus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 419497)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 61X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014655715.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 05:46:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,254
            CDSs (total)                      :: 9,172
            Genes (coding)                    :: 8,973
            CDSs (with protein)               :: 8,973
            Genes (RNA)                       :: 82
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 199
            CDSs (without protein)            :: 199
            Pseudo Genes (ambiguous residues) :: 0 of 199
            Pseudo Genes (frameshifted)       :: 83 of 199
            Pseudo Genes (incomplete)         :: 153 of 199
            Pseudo Genes (internal stop)      :: 16 of 199
            Pseudo Genes (multiple problems)  :: 50 of 199
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:57:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 281721
            Orig. end                         :: 329620
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BNBM01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..47899
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NRPS-like"
                     /product="T1PKS"
                     /region_number="2"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX) and not alpha_am_amid)"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..47899
                     /SMILES="C1=CC(=O)C(N)C=C1C(=O)C=CC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="chemical_hybrid"
                     /product="NRPS-like"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..47899
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:27899](+)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..27899
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     protocluster    1..47899
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:27899](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      20001..27899
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     misc_feature    2924..2938
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     misc_feature    complement(3234..3248)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.68"
                     /tool="antismash"
     misc_feature    5559..5572
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.84"
                     /tool="antismash"
     misc_feature    complement(7932..7946)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     misc_feature    complement(12661..12670)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    complement(12963..12975)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     misc_feature    12965..12975
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     misc_feature    13985..13999
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.6"
                     /tool="antismash"
     misc_feature    14036..14056
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 23.88"
                     /tool="antismash"
     misc_feature    complement(14124..14138)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.3"
                     /tool="antismash"
     misc_feature    14125..14139
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: strong, score: 21.57"
                     /tool="antismash"
     misc_feature    15572..15586
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.6"
                     /tool="antismash"
     misc_feature    15623..15643
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 23.88"
                     /tool="antismash"
     misc_feature    complement(15817..15826)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    complement(15912..15926)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.69"
                     /tool="antismash"
     gene            complement(16247..17080)
                     /locus_tag="IE325_RS22970"
                     /old_locus_tag="GCM10018780_46430"
     CDS             complement(16247..17080)
                     /NRPS_PKS="Domain: Abhydrolase_1 (28-262). E-value:
                     3.3e-29. Score: 94.1. Matches aSDomain:
                     nrpspksdomains_IE325_RS22970_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330261.1"
                     /locus_tag="IE325_RS22970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_46430"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_190071887.1"
                     /sec_met_domain="PF00561 (E-value: 4.1e-17, bitscore: 57.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.6e-22, bitscore:
                     75.6, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDWKLSKTYDSTAGEVRWDRFGETGRDPVVLLHGTPFSSYVWRG
                     IARSLAHHHQVFVWDMPGYGASAKAEGQDVSLAAQGRVFTELLTHWGLTEPAVIAHDFG
                     GAVALRAHLLHDARYRKLTVVDPVALAPWGSPFFRLVGRHSAVFDQLPPALHRALVREY
                     VTSASSPGLHPVTLDRLVEPWLGDDGQPAFYRQIAQADQRYTDEIQERYGTIDIPVLVC
                     WGTDDAWIPVAKAHELASLIPGAQLRLIPGAGHLVQEDNPAELLAALVAFLHDLD"
     aSDomain        complement(16295..16996)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS22970_Abhydrolase_1.1"
                     /evalue="3.30E-29"
                     /label="IE325_RS22970_Abhydrolase_1.1"
                     /locus_tag="IE325_RS22970"
                     /protein_end="262"
                     /protein_start="28"
                     /score="94.1"
                     /tool="antismash"
                     /translation="PVVLLHGTPFSSYVWRGIARSLAHHHQVFVWDMPGYGASAKAEGQ
                     DVSLAAQGRVFTELLTHWGLTEPAVIAHDFGGAVALRAHLLHDARYRKLTVVDPVALAP
                     WGSPFFRLVGRHSAVFDQLPPALHRALVREYVTSASSPGLHPVTLDRLVEPWLGDDGQP
                     AFYRQIAQADQRYTDEIQERYGTIDIPVLVCWGTDDAWIPVAKAHELASLIPGAQLRLI
                     PGAGHLVQEDNP"
     gene            complement(17686..18804)
                     /locus_tag="IE325_RS22975"
                     /old_locus_tag="GCM10018780_46440"
     CDS             complement(17686..18804)
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015663082.1"
                     /locus_tag="IE325_RS22975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_46440"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_190071888.1"
                     /transl_table=11
                     /translation="MVSGRLEDRRWSQEPRHALLAVSITMIVVVTVVDILAPSNVHLGP
                     FLVAAPAVTASFAGPRTTACVGALAVLAQAVVATVRTTLIDLNHSFQLITLILMSAFAT
                     VFAAWRERHERELKQLRSVATTAQEVVLKPLPQRVGPLRIASVYLAAESEAQIGGDLYA
                     AARTERATRIVIGDVRGKGLEAVGDAALLLGAFRGAAHRQADLPALMAFLEGTVSSDLD
                     DPSALDAAAEDRGEAFITAAALDIPDDELVLHLVNCGHPPPLLLRHGEVGPLEVRHPAP
                     PLGLTEFVESELSEEEFAFEDGDIVLLYTDGVIEARDHEGTFYPLAERVAGRAGKGPDA
                     LLAHLCKDLMRHAGGHLGDDAAMVAIERMPRQ"
     misc_feature    18798..18811
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.33"
                     /tool="antismash"
     gene            complement(18884..19348)
                     /locus_tag="IE325_RS22980"
                     /old_locus_tag="GCM10018780_46450"
     CDS             complement(18884..19348)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557760.1"
                     /locus_tag="IE325_RS22980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_46450"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_190071889.1"
                     /transl_table=11
                     /translation="MTWLETSTENCTVQRTLDLIGEKWSLLVLRDAMNGVRRFDDFRRH
                     VGLSEAVLSDRLRKLVAAGVLDTVPYREPGHRTRHEYRLSRKGWDLWPVMLALKQWGDR
                     YTADPEGPPLEVRHRDCGEPLETVVVCTGGHGPLTPREAYTRPGTAAHAM"
     gene            19438..19932
                     /locus_tag="IE325_RS22985"
                     /old_locus_tag="GCM10018780_46460"
     CDS             19438..19932
                     /EC_number="3.1.2.-"
                     /GO_function="GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1144: thioesterase superfamily protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557759.1"
                     /locus_tag="IE325_RS22985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_46460"
                     /product="PaaI family thioesterase"
                     /protein_id="WP_190071890.1"
                     /transl_table=11
                     /translation="MTRSRTYEWQDPSISAADVGQGSGLDFLRAVLSGRLPAPPIAATL
                     RFTLEQVDFGHAVFALEPGEEHYNPIGSVHGGVYATLLDSAAGCAVQSVLSAGMGYTSL
                     DLTVKFLRPITVDTGKVRAVGTVLNHGRRTALAQADLLDSEDRLLAHATSSCMLFPVPA
                     R"
     gene            20001..27899
                     /locus_tag="IE325_RS22990"
                     /old_locus_tag="GCM10018780_46470"
     CDS             20001..27899
                     /NRPS_PKS="Domain: CAL_domain (34-438). E-value: 7.2e-172.
                     Score: 564.8. Matches aSDomain:
                     nrpspksdomains_IE325_RS22990_CAL_domain.1"
                     /NRPS_PKS="Domain: PKS_PP (520-605). E-value: 1.5e-23.
                     Score: 75.0. Matches aSDomain:
                     nrpspksdomains_IE325_RS22990_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (630-1053). E-value:
                     7.8e-180. Score: 590.2. Matches aSDomain:
                     nrpspksdomains_IE325_RS22990_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (1156-1440). E-value: 5.7e-105.
                     Score: 342.9. Matches aSDomain:
                     nrpspksdomains_IE325_RS22990_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (1509-1671). E-value: 1.6e-56.
                     Score: 183.2. Matches aSDomain:
                     nrpspksdomains_IE325_RS22990_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (1970-2148). E-value: 3.7e-63.
                     Score: 204.7. Matches aSDomain:
                     nrpspksdomains_IE325_RS22990_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2242-2327). E-value: 7.4e-25.
                     Score: 79.1. Matches aSDomain:
                     nrpspksdomains_IE325_RS22990_PKS_PP.2"
                     /NRPS_PKS="Domain: Thioesterase (2423-2628). E-value:
                     3.4e-30. Score: 98.1. Matches aSDomain:
                     nrpspksdomains_IE325_RS22990_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005473642.1"
                     /locus_tag="IE325_RS22990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_46470"
                     /product="type I polyketide synthase"
                     /protein_id="WP_190071891.1"
                     /sec_met_domain="AMP-binding (E-value: 6.6e-101, bitscore:
                     332.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 3.3e-228, bitscore:
                     752.0, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 8.2e-94, bitscore:
                     308.2, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 3.2e-104, bitscore:
                     342.9, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 2.8e-64, bitscore:
                     210.6, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9e-13, bitscore:
                     43.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 5.8e-19, bitscore:
                     63.5, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGREGLIRPLPELLKEHAERAPSRVAYSDASRSVTYAELERRTRA
                     LAGHLTRTGLRRGDRVAICLGNRVETVESCLAVLRAGLVGVPLDPRSADAELAHFLQDS
                     GAAYVITDAAHLAQLRRLGPPYDDMGALVTDERFQRAAEGDGTAEIDVLGLDDPAWMLY
                     TSGTTHRPKGVLSTQRAALWSTAACYAPILGLSPDDRLLWPLPLFHSFSHSLAILGVTA
                     VGATARIAGELLPPGGLRQELDADHAELGGPITLLAGVPATYHRLVESSGSTPPQGPRM
                     CLVAGAPSGPALRTAVEESLGAPLLDAYGSTETCGMIATNRPEGPRVDGSCGPPVPGVD
                     VRIVEPRGGEDVRDGAEGEVWVRSPGLMTGYHGQPEATAAALRDGWYRTGDLGRRVEYG
                     HLRLTGRVSELIIRGGENIHPTEIEQVLSQCPGVSDAVVVGVPHDVLGEVPVACVVPGP
                     DGIDARRVLAECRTRLAGYKVPAEIREIAAVPRTASGKIARHRLVVPAPVADAPAPAAL
                     RERLRSLSRDDQERAIRETVLVETAEVCGQASPELPDPASPFAELGMTSVGVVELVDRL
                     GALTGLSLPTTLVFDHPTPAEVARHLRAALFEDEPGRRPNPSGGQGRAAHEDDPVVIVA
                     MGCRYPGDVNSPEDLWELVAQGRDAVSEFPTDRGWDLDALYDPDPDRIGTSYTRHGGFL
                     HRAAEFDAGLFGISPREALAMDPQQRLLLETSWEVWERAGIDQASLRESDTGVFVGVMY
                     ADYAHRFTHVHELEAHLGLGSAGSVASGRISYAYGLRGPAITVDTACSSSLVALHWAAR
                     ALRSGECSLALAGGVTVMATPKPFLAFSRQRGLAPDGRCKSFSAAADGTAWGEGVGLVL
                     LERLSDARRNGHPVLAVLRGSAVNSDGASNGLTAPHGPAQQRLITQALADAGLGAADVD
                     AVEAHGTGTRLGDPIEAQALLATYGQDRERPLWLGSVKSNLGHTQAAAGVAGVIKMVQA
                     MRHGELPRTLHADSPTPHVDWSAGRVELLTSPRPWPAASDRPRRAGVSAFGIGGTNAHV
                     ILEEPPGTERAVSQEQATPLPLLLSAADETALRAQASRLAAHAARRPDLTPADLAHSLA
                     VSRSALTHRALVPADDRTRMLDALGALARGRDATGVVRGLADPGIRTAFLFTGQGAQRP
                     RMGAELCATFPVFAKAFDEVCRYLDDRLPQPLSTVLSAEPGSPEAALVDRTDFAQAGLF
                     AFEVALFRLLESWGVRADRLVGHSVGELAAAHVAGVLDLSDAATLVAARGRLMRGLPEG
                     GAMVAVDAAEDEVVAAIEGLDGVAVAAVNGPRSVVISGARDAVLAVAAGFEARGRRAVR
                     LRVSHAFHSPLMEPMLGEFLDVARELTFREPRIPIISTVTGRPSELSLPEYWVRHARLP
                     VRFADAVRRLVDDGISACLELGPGPALTAAATDCLNGSVLAVAAGGGAYEPETLLSALA
                     RLRVAGVGVDWAAVYAAPGARRVELPTYAFQRQRYWLDASPVAAADAGPLLSPAFPVPD
                     TGRTVLTGLLSVANRPWIADHVVAGRVVVPATVFVEMAVRAGDEVGCGTVDELVMPTPL
                     ALPGSAGVRVQVVVGAPDDSGTRSVDIYSRPEGAEDTVPWTRNASGRLLREHAAHGEPM
                     PWPPQGAEEVDLTDAYAALADAGLGYGPAFQGVGAVRRRGDDVFAEVRLPAALISEADR
                     YGLHPALFDAALHAPLLARPADTGVVRVPFEWSGVSLYASGATELRVAVTSTGTDTLSL
                     TLADLSGRLVARVESLTTRELRADWAELTVGVGGDLIRKALLRPEWTALELPAGDAHAP
                     AWAVRGPDELNLAGFLPGGVDPEFVAVTAIAGADDSGPLPAVHESTGRVLKTLQDWQDD
                     PGTAGARLVVVTRDATGPVPDLAGAAVWGLVRAAQSELPGRVVLVDVDGRPESLRLLPA
                     AVASGEPQLRLRDGQVTVPRLTTAADATGTQSSFAADGTVLITGGTGALGAELARHLVT
                     EHGVRDLLLTGRRGDRAPGARELRRDLEELGARVGIVACDVGDRAALAALVEGCEPPLT
                     AVVHAAGVLDDGVLDAMTPERIAAVLRPKADAAWHLHELTRGMGLSAFVVFSSVSGLLG
                     RAGQGNYAAANSFLDALAHRRAAEGLPALSLAWGPWEHGDGMAAELPRQRPQARDLLVP
                     LTTGQGLALFDAALRATAPVLAPILLDREALRSDAGQLPPPLRGLVRRHRPAAATTASG
                     PPGQPPEPGAWRRRLAPISPPEREAVLVELLRADVAAVLGYPDAGALPAGKALADLGFD
                     SLTAVQIRNALSTALGLRLPAAVVFEHRTAEDLARHLLALLEDEPDDEPGDEPDAEPAP
                     DERPAHTLSALFRTVSAGGHPVAAMHLLVTASLALPTFTAAQGRAHALPPLRRSHGDSP
                     GSGRPTVVYFPAYHPSLASADFPSFHRAFQDDLDVLEFPHPGIGAGPAVPEDRAALART
                     HAESVLRQVGDGPFVVVGRSAGGNVAHLVTHELECMGRAPSGLVLLDTYHITPDNSAED
                     WLLSLAAPPRPDAGQPVLTGDDDTALAAMGAYNRIFLDWNPEPVTTPTLLVRALRPTPA
                     MAASADADDWRTSWPSAHDVVDVPGDHLTMMREHAGTTVSAIRAWIDARA"
     aSDomain        20103..21314
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS22990_CAL_domain.1"
                     /evalue="7.20E-172"
                     /label="IE325_RS22990_CAL_domain.1"
                     /locus_tag="IE325_RS22990"
                     /protein_end="438"
                     /protein_start="34"
                     /score="564.8"
                     /specificity="Minowa: AHBA"
                     /tool="antismash"
                     /translation="TYAELERRTRALAGHLTRTGLRRGDRVAICLGNRVETVESCLAVL
                     RAGLVGVPLDPRSADAELAHFLQDSGAAYVITDAAHLAQLRRLGPPYDDMGALVTDERF
                     QRAAEGDGTAEIDVLGLDDPAWMLYTSGTTHRPKGVLSTQRAALWSTAACYAPILGLSP
                     DDRLLWPLPLFHSFSHSLAILGVTAVGATARIAGELLPPGGLRQELDADHAELGGPITL
                     LAGVPATYHRLVESSGSTPPQGPRMCLVAGAPSGPALRTAVEESLGAPLLDAYGSTETC
                     GMIATNRPEGPRVDGSCGPPVPGVDVRIVEPRGGEDVRDGAEGEVWVRSPGLMTGYHGQ
                     PEATAAALRDGWYRTGDLGRRVEYGHLRLTGRVSELIIRGGENIHPTEIEQVLSQCPGV
                     SDAVV"
     aSModule        20103..21815
                     /complete
                     /domains="nrpspksdomains_IE325_RS22990_CAL_domain.1"
                     /domains="nrpspksdomains_IE325_RS22990_PKS_PP.1"
                     /locus_tags="IE325_RS22990"
                     /monomer_pairings="AHBA -> AHBA"
                     /starter_module
                     /tool="antismash"
                     /type="pks"
     CDS_motif       20226..20267
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS22990_0001"
                     /evalue="4.60E-02"
                     /label="NRPS-A_a2"
                     /locus_tag="IE325_RS22990"
                     /protein_end="89"
                     /protein_start="75"
                     /score="7.7"
                     /tool="antismash"
                     /translation="LAVLRAGLVGVPLD"
     CDS_motif       20475..20528
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS22990_0002"
                     /evalue="2.30E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="IE325_RS22990"
                     /protein_end="176"
                     /protein_start="158"
                     /score="17.2"
                     /tool="antismash"
                     /translation="AWMLYTSGTTHRPKGVLS"
     CDS_motif       21060..21143
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS22990_0003"
                     /evalue="1.20E-08"
                     /label="NRPS-A_a6"
                     /locus_tag="IE325_RS22990"
                     /protein_end="381"
                     /protein_start="353"
                     /score="27.2"
                     /tool="antismash"
                     /translation="DGAEGEVWVRSPGLMTGYHGQPEATAAA"
     CDS_motif       21303..21404
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS22990_0004"
                     /evalue="2.80E+01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="IE325_RS22990"
                     /protein_end="468"
                     /protein_start="434"
                     /score="-1.9"
                     /tool="antismash"
                     /translation="DAVVVGVPHDVLGEVPVACVVPGPDGIDARRVLA"
     aSDomain        21561..21815
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS22990_PKS_PP.1"
                     /evalue="1.50E-23"
                     /label="IE325_RS22990_PKS_PP.1"
                     /locus_tag="IE325_RS22990"
                     /protein_end="605"
                     /protein_start="520"
                     /score="75.0"
                     /tool="antismash"
                     /translation="LRSLSRDDQERAIRETVLVETAEVCGQASPELPDPASPFAELGMT
                     SVGVVELVDRLGALTGLSLPTTLVFDHPTPAEVARHLRAA"
     aSDomain        21891..23159
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS22990_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="7.80E-180"
                     /label="IE325_RS22990_PKS_KS.1"
                     /locus_tag="IE325_RS22990"
                     /protein_end="1053"
                     /protein_start="630"
                     /score="590.2"
                     /tool="antismash"
                     /translation="VVIVAMGCRYPGDVNSPEDLWELVAQGRDAVSEFPTDRGWDLDAL
                     YDPDPDRIGTSYTRHGGFLHRAAEFDAGLFGISPREALAMDPQQRLLLETSWEVWERAG
                     IDQASLRESDTGVFVGVMYADYAHRFTHVHELEAHLGLGSAGSVASGRISYAYGLRGPA
                     ITVDTACSSSLVALHWAARALRSGECSLALAGGVTVMATPKPFLAFSRQRGLAPDGRCK
                     SFSAAADGTAWGEGVGLVLLERLSDARRNGHPVLAVLRGSAVNSDGASNGLTAPHGPAQ
                     QRLITQALADAGLGAADVDAVEAHGTGTRLGDPIEAQALLATYGQDRERPLWLGSVKSN
                     LGHTQAAAGVAGVIKMVQAMRHGELPRTLHADSPTPHVDWSAGRVELLTSPRPWPAASD
                     RPRRAGVSAFGIGGTNAHVILEEP"
     aSModule        21891..27884
                     /complete
                     /domains="nrpspksdomains_IE325_RS22990_PKS_KS.1"
                     /domains="nrpspksdomains_IE325_RS22990_PKS_AT.1"
                     /domains="nrpspksdomains_IE325_RS22990_PKS_DH.1"
                     /domains="nrpspksdomains_IE325_RS22990_PKS_KR.1"
                     /domains="nrpspksdomains_IE325_RS22990_PKS_PP.2"
                     /domains="nrpspksdomains_IE325_RS22990_Thioesterase.1"
                     /final_module
                     /locus_tags="IE325_RS22990"
                     /monomer_pairings="mal -> ccmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       22371..22418
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS22990_0005"
                     /evalue="1.40E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE325_RS22990"
                     /protein_end="806"
                     /protein_start="790"
                     /score="20.1"
                     /tool="antismash"
                     /translation="GPAITVDTACSSSLVA"
     CDS_motif       22794..22838
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS22990_0006"
                     /evalue="6.70E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE325_RS22990"
                     /protein_end="946"
                     /protein_start="931"
                     /score="12.0"
                     /tool="antismash"
                     /translation="VEAHGTGTRLGDPIE"
     CDS_motif       22893..22937
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS22990_0007"
                     /evalue="2.50E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE325_RS22990"
                     /protein_end="979"
                     /protein_start="964"
                     /score="10.5"
                     /tool="antismash"
                     /translation="GSVKSNLGHTQAAAG"
     aSDomain        23469..24320
                     /ASF="Malonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS22990_PKS_AT.1"
                     /evalue="5.70E-105"
                     /label="IE325_RS22990_PKS_AT.1"
                     /locus_tag="IE325_RS22990"
                     /protein_end="1440"
                     /protein_start="1156"
                     /score="342.9"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGAQRPRMGAELCATFPVFAKAFDEVCRYLDDRLPQPLSTV
                     LSAEPGSPEAALVDRTDFAQAGLFAFEVALFRLLESWGVRADRLVGHSVGELAAAHVAG
                     VLDLSDAATLVAARGRLMRGLPEGGAMVAVDAAEDEVVAAIEGLDGVAVAAVNGPRSVV
                     ISGARDAVLAVAAGFEARGRRAVRLRVSHAFHSPLMEPMLGEFLDVARELTFREPRIPI
                     ISTVTGRPSELSLPEYWVRHARLPVRFADAVRRLVDDGISACLELGPGPALTAAATDCL
                     NGS"
     CDS_motif       23472..23516
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS22990_0008"
                     /evalue="7.00E-04"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="IE325_RS22990"
                     /protein_end="1172"
                     /protein_start="1157"
                     /score="12.5"
                     /tool="antismash"
                     /translation="FTGQGAQRPRMGAEL"
     CDS_motif       23727..23834
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS22990_0009"
                     /evalue="3.70E-17"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="IE325_RS22990"
                     /protein_end="1278"
                     /protein_start="1242"
                     /score="54.4"
                     /tool="antismash"
                     /translation="DRLVGHSVGELAAAHVAGVLDLSDAATLVAARGRLM"
     CDS_motif       23928..23966
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS22990_0010"
                     /evalue="2.30E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE325_RS22990"
                     /protein_end="1322"
                     /protein_start="1309"
                     /score="14.4"
                     /tool="antismash"
                     /translation="AAVNGPRSVVISG"
     CDS_motif       24180..24215
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS22990_0011"
                     /evalue="9.70E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="IE325_RS22990"
                     /protein_end="1405"
                     /protein_start="1393"
                     /score="12.7"
                     /tool="antismash"
                     /translation="YWVRHARLPVRF"
     CDS_motif       24324..24353
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS22990_0012"
                     /evalue="5.50E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="IE325_RS22990"
                     /protein_end="1451"
                     /protein_start="1441"
                     /score="-1.6"
                     /tool="antismash"
                     /translation="LAVAAGGGAY"
     aSDomain        24528..25013
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS22990_PKS_DH.1"
                     /evalue="1.60E-56"
                     /label="IE325_RS22990_PKS_DH.1"
                     /locus_tag="IE325_RS22990"
                     /protein_end="1671"
                     /protein_start="1509"
                     /score="183.2"
                     /tool="antismash"
                     /translation="PLLSPAFPVPDTGRTVLTGLLSVANRPWIADHVVAGRVVVPATVF
                     VEMAVRAGDEVGCGTVDELVMPTPLALPGSAGVRVQVVVGAPDDSGTRSVDIYSRPEGA
                     EDTVPWTRNASGRLLREHAAHGEPMPWPPQGAEEVDLTDAYAALADAGLGYGPAFQGV"
     CDS_motif       24609..24683
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS22990_0013"
                     /evalue="6.70E-10"
                     /label="PKSI-DH_m2"
                     /locus_tag="IE325_RS22990"
                     /protein_end="1561"
                     /protein_start="1536"
                     /score="31.4"
                     /tool="antismash"
                     /translation="WIADHVVAGRVVVPATVFVEMAVRA"
     aSDomain        25911..26444
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS22990_PKS_KR.1"
                     /evalue="3.70E-63"
                     /label="IE325_RS22990_PKS_KR.1"
                     /locus_tag="IE325_RS22990"
                     /protein_end="2148"
                     /protein_start="1970"
                     /score="204.7"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GTVLITGGTGALGAELARHLVTEHGVRDLLLTGRRGDRAPGAREL
                     RRDLEELGARVGIVACDVGDRAALAALVEGCEPPLTAVVHAAGVLDDGVLDAMTPERIA
                     AVLRPKADAAWHLHELTRGMGLSAFVVFSSVSGLLGRAGQGNYAAANSFLDALAHRRAA
                     EGLPALSLAWGPWEH"
     CDS_motif       25914..26015
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS22990_0014"
                     /evalue="1.20E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE325_RS22990"
                     /protein_end="2005"
                     /protein_start="1971"
                     /score="30.8"
                     /tool="antismash"
                     /translation="TVLITGGTGALGAELARHLVTEHGVRDLLLTGRR"
     CDS_motif       26292..26393
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS22990_0015"
                     /evalue="2.40E-18"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE325_RS22990"
                     /protein_end="2131"
                     /protein_start="2097"
                     /score="58.7"
                     /tool="antismash"
                     /translation="AFVVFSSVSGLLGRAGQGNYAAANSFLDALAHRR"
     aSDomain        26727..26981
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS22990_PKS_PP.2"
                     /evalue="7.40E-25"
                     /label="IE325_RS22990_PKS_PP.2"
                     /locus_tag="IE325_RS22990"
                     /protein_end="2327"
                     /protein_start="2242"
                     /score="79.1"
                     /tool="antismash"
                     /translation="LAPISPPEREAVLVELLRADVAAVLGYPDAGALPAGKALADLGFD
                     SLTAVQIRNALSTALGLRLPAAVVFEHRTAEDLARHLLAL"
     aSDomain        27270..27884
                     /ASF="active site serine present: True"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS22990_Thioesterase.1"
                     /evalue="3.40E-30"
                     /label="IE325_RS22990_Thioesterase.1"
                     /locus_tag="IE325_RS22990"
                     /protein_end="2628"
                     /protein_start="2423"
                     /score="98.1"
                     /tool="antismash"
                     /translation="SADFPSFHRAFQDDLDVLEFPHPGIGAGPAVPEDRAALARTHAES
                     VLRQVGDGPFVVVGRSAGGNVAHLVTHELECMGRAPSGLVLLDTYHITPDNSAEDWLLS
                     LAAPPRPDAGQPVLTGDDDTALAAMGAYNRIFLDWNPEPVTTPTLLVRALRPTPAMAAS
                     ADADDWRTSWPSAHDVVDVPGDHLTMMREHAGTTVSAIRAWI"
     CDS_motif       27423..27491
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS22990_0016"
                     /evalue="1.40E-04"
                     /label="NRPS-te1"
                     /locus_tag="IE325_RS22990"
                     /protein_end="2497"
                     /protein_start="2474"
                     /score="14.4"
                     /tool="antismash"
                     /translation="DGPFVVVGRSAGGNVAHLVTHEL"
     gene            28110..28385
                     /locus_tag="IE325_RS22995"
                     /old_locus_tag="GCM10018780_46480"
     CDS             28110..28385
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642800.1"
                     /locus_tag="IE325_RS22995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_46480"
                     /product="DUF6355 family natural product biosynthesis
                     protein"
                     /protein_id="WP_190071995.1"
                     /transl_table=11
                     /translation="MVTGVLASVALVLTSLGAVTAQAIPAAADPCGFYETGSDAFYNHC
                     TSDGSRVVIKVRVAYAADYERCVGPGTTWLGSAGKIQGAHYVGRTC"
     gene            28509..29468
                     /locus_tag="IE325_RS23000"
                     /old_locus_tag="GCM10018780_46490"
     CDS             28509..29468
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.5"
                     /locus_tag="IE325_RS23000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_46490"
                     /product="MFS transporter"
                     /protein_id="WP_190071892.1"
                     /transl_table=11
                     /translation="MGAESSKAVRTGAFVAVAVALFCIQLDFFALNLAVPGIADEFDVT
                     ASAAQWTLSAYMLAIGCCFIVGGRVGDVFGRRGVLLGGTALFVAGSVGCALAPDLWALV
                     GARIVQGVGAGFVFPVSVAVISNAFPDPTRARALGAVFGIANVGTALGPFAGGGFTEGP
                     GWRWIFWLLAPLSLLSLCVAYGCVPDSRDPDAPRQLDLIGCLTVVCALAALTLAVERGS
                     AWGWDHARTLTLLAVAALAGWLFVRRERRARHPLIDLRLFRNTPYVLVTGTDAAYDAIL
                     RFGGAVILAASAVVIAVRHRLVALGTVPPLGPGGGRLP"
     gene            29465..31606
                     /locus_tag="IE325_RS23005"
                     /old_locus_tag="GCM10018780_46500"
     CDS             29465..31606
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018491068.1"
                     /locus_tag="IE325_RS23005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_46500"
                     /product="FUSC family protein"
                     /protein_id="WP_190071893.1"
                     /transl_table=11
                     /translation="MKPTAERSLILHRSVRVTLAASVGFYTFVYGLDEPVLALYALFAP
                     ISLGLLSPIPGSGRQRAEVMLKALPVGLLLVALGTVLAVRTWAAVLGMLVVGFCLAFAA
                     IAGPRPAAAAPGLQLFYILACFPPYEPETLWLRLAGLTFGVVLLALCELFLLPQPAGPT
                     YRTALADALVTAGDVIAGRTVLSPEALREAGARLRLSDIPPAERPAGPGRAVRGLAQAG
                     AAARRLLEQLARLTETGELPALVREGAGGAGGHPATATGPLLPQVMSLCDETAAALRTG
                     RAAPGPQRMDRAIDDFQRMRVRQVTGAADRVPPVPVLRRQAALLAVAESTRILEISVRV
                     ALDGRRTPPIEPRELFWYTRAATPRLWERRITGNMTLRSVQFQNAVRIAVALAVARLVA
                     GSLDLTHGFWVLLTVLTLSRTTVGETWGAIRQAVTGNLLGAVAAGALLIGLGRHTDGYA
                     AILALAMLIAFALGPLLGIAWAQGLFTLVVATAFAQIAPASWQLAEARIVDVMTGSAIG
                     LLCGLLAWPAGARREVHRTMAGLLGECGPLIKGTVDLLTATPPGSVPAPPTLPALHRLR
                     LAESAYAQFRSEPGSGASAGADWHAVLITASHILLGAQWLPRFDLPTAAVPPDAGDRAR
                     AGARALAGTTDRLAALCRGRRSRPPAAPPPLWEPAGPPLPTLVDLDMWLRGLSHQLTRI
                     EAGLPEAPRGTPTAGRDAP"
     gene            31603..32751
                     /locus_tag="IE325_RS23010"
                     /old_locus_tag="GCM10018780_46510"
     CDS             31603..32751
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018888629.1"
                     /locus_tag="IE325_RS23010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_46510"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_190071894.1"
                     /transl_table=11
                     /translation="MTGRDLRSELRPPSPLRGWVWWLPLVAVVVDLAAEFIVRGREPVS
                     FMLIAVPPLAAATRGPRGTAMSAVVCLGLQMWMAARRPGHFDEQHHVAVYVATTLIGIA
                     SVALARQRERTRQHLIRANSVAEAMQRTLLRPVPRRLGPVRAAAFYEAGEGGTLVGGDL
                     YDVCETPFGVRAIIGDVRGKGLDAVQTVAAVLGSFRVSAHEWESLSSLAERLELSIARN
                     SPAGDAGDPELFVTALVLEFPADGGEVRVVDRGHPPPLAVGPDGARRLATAPGLPLGLG
                     ALTPDGVEATVHVLRPSEVLVLHTDGVSEARDTDGVFYPVQERLGERFTGERAPDPETV
                     VSFVRTDSERWAATESDSDDRAVLALTLAAPGRGITARADRA"
     gene            complement(32726..33886)
                     /locus_tag="IE325_RS23015"
                     /old_locus_tag="GCM10018780_46520"
     CDS             complement(32726..33886)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014181490.1"
                     /locus_tag="IE325_RS23015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_46520"
                     /product="exo-alpha-sialidase"
                     /protein_id="WP_190071895.1"
                     /transl_table=11
                     /translation="MTHPLLDAYARTDTTLPAPTVQSHAANLTVLPGGDVGCVWFGGTQ
                     EGMADISVWFSRLAPGGMVWTDPVRLSEDPTRSEQNPLLFPTPSGALWLLHTAQRGGDQ
                     DTAEVRLRVSHDGAGSWDATRTLFPATPGDGGVFVRQPPVVLPTGRLLLPVFRCVVTPG
                     VKWSGDLDTSAVMISDDEGGTWREEPVPGSTGLVHMNVHRLPDGSLVALFRSRRADHVH
                     RSVSLDDGDTWSDPEPLALPNNNSSIQYVPLADGRLALVYNHSSAADATARRVSLYDEI
                     DDSGALATGEEAGATAVKQAPSAAFWGAPRAPLSLALSSDAGRTWPLRADLVTGDGHCL
                     TNNSRDGVNRELSYPSIVQSPDGALHIAYTHHRKVIRHIRLGPRGR"
     gene            complement(33883..34296)
                     /locus_tag="IE325_RS23020"
                     /old_locus_tag="GCM10018780_46530"
     CDS             complement(33883..34296)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006129988.1"
                     /locus_tag="IE325_RS23020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_46530"
                     /product="hypothetical protein"
                     /protein_id="WP_190071896.1"
                     /transl_table=11
                     /translation="MTPAEFTAARRAREQLLAHWRLLDAPVAILPLVDTSAQAAEAVAA
                     VRYPPHCRRSYGPMRSSLRIGPDPALADAFEATLVRVREAAAASGIHNPDGPSATKRLA
                     KSITYATVSCDLVHPEQTARHHPTSARTPGATP"
     misc_feature    34297..34311
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.8"
                     /tool="antismash"
     gene            complement(34479..35324)
                     /locus_tag="IE325_RS23025"
                     /old_locus_tag="GCM10018780_46540"
     CDS             complement(34479..35324)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014181488.1"
                     /locus_tag="IE325_RS23025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_46540"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_190071897.1"
                     /transl_table=11
                     /translation="MNQPSAPPPFLAVEDLVVDYDTPAGPVRAVDHVSFDVPRGGSLAV
                     VGESGCGKSTLARAIVRLLKPVSGRVVLDGTDLAALSERRLRPLRRRAQMVFQDPYGSL
                     DPHLSAERIVAEPLRLAGVRDKAERRRCAAELLDRVGLPASARERRPAEFSGGQRQRIG
                     IARALASEPDLLVCDEATSALDVSVQAQVLDLLRELQAETGITYIVIAHHLGVVREIST
                     DMVVLKAGRVIERGRTAAVLASPTDPYTRALRRAALDPAAIRGLKPRAATAVSPEGTGK
                     "
     gene            complement(35321..36172)
                     /locus_tag="IE325_RS23030"
                     /old_locus_tag="GCM10018780_46550"
     CDS             complement(35321..36172)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056760.1"
                     /locus_tag="IE325_RS23030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_46550"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_190071898.1"
                     /transl_table=11
                     /translation="MAEDASPLLEVEDLQIELVTHRGVVRAVDGVSFTVGQGETVTLIG
                     ESGSGKSTTAMGVLRLLPEGLAVLSGTARVGGEDVVADPEAARRVRGRTVSLIPQDPMT
                     ALSPVHTIGRQLGDALRLRHPGLSRAEARERGTRLLDQVRISEPGTRWKTYPHQFSGGM
                     LQRILIAIALAAEPRLLVADEPTSALDATVQAGVLDLLLDLQERTGVGMLMITHDLGVA
                     RLVSDRIHVMKEGRFVESGPAERIVERPTHPYTRTLLAAVPALGPWDEDGLADHTPLGA
                     AR"
     gene            complement(36176..37081)
                     /locus_tag="IE325_RS23035"
                     /old_locus_tag="GCM10018780_46560"
     CDS             complement(36176..37081)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056759.1"
                     /locus_tag="IE325_RS23035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_46560"
                     /product="ABC transporter permease"
                     /protein_id="WP_190071899.1"
                     /transl_table=11
                     /translation="MTTTLAPPERPSAVSERHLARSSAARQRRGARVKLWAGAFCTALV
                     ALPVALAGLLPLADPNTQDLSRRRLPPLTDGHLFGTDQLGRDLLSRLLHGGQVSLTVGV
                     LAVVVSGLIGIAAGSAAGYFGGWIDTVVSRLLEAQLALPLLMMLLLVVALFGPSVTVIT
                     CVIAVAQWPEVARLTRSLVLVEREKPYVAAARLLGLRGWSVLARHIVPNVLRPASLVVL
                     LLLAQAVLLESALSFLGAGPQRPFATWGRIISDGQDYITTSWWLVTLPGLVIALLVVGV
                     NLLGDGLRDRVRTHKPAKGV"
     gene            complement(37085..38014)
                     /locus_tag="IE325_RS23040"
                     /old_locus_tag="GCM10018780_46570"
     CDS             complement(37085..38014)
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1118:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014181485.1"
                     /locus_tag="IE325_RS23040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_46570"
                     /product="ABC transporter permease"
                     /protein_id="WP_190071900.1"
                     /transl_table=11
                     /translation="MSRYLARRLGQSLLTVFLTVSTVFVLVRLAPGDPAAAYAGPTATS
                     ADLARIREEFGLGEPLITQYGIFLRDLLTGDLGTSYSFHSSALDVVLERMPYTITLSVA
                     AIAVTVAVAVPLGVWMARRADTKRELGANVLTIAGQSMPDFWTGVMLLTVFAVLLPVLP
                     ASGFTSWSGLILPTVTVAILQLALVSRLVRREMTTALASPYITVARSRGVSERALTWRY
                     ALANSAVPLVTAVGTRFAALLNGVVVVEVVFGWPGVGSLVVRALETRDYPLIQATVLVT
                     ATLAILVQLLVDLAYPLLDPRVRLGKAA"
     gene            complement(38018..39613)
                     /locus_tag="IE325_RS23045"
                     /old_locus_tag="GCM10018780_46580"
     CDS             complement(38018..39613)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056757.1"
                     /locus_tag="IE325_RS23045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_46580"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_190071901.1"
                     /transl_table=11
                     /translation="MTRTPPRTTPTPPHETLTRRTLLRWGAAGGAGLGLAPLAACAGPT
                     GAPGPGTLTLGLNRSLVSLDNKLNQFDAAVTVQRAVRQALTAIGPGMKPTPVLADRFEM
                     TAPTTWSVRLREGIRYSDGRPVTVEDVATAVRMYGEVAGSFVLGLFPELPSVEATGART
                     FLLHTRQPVPVLDRLMANILITPAKDNRPEELRSGVGTGPYRVVGANSGAGEYTLARVP
                     RYWGGRPAVERVRVRFVPEESSRVVALRSGELDVIDTITPDSAEQLTGLPGVHLEQTSG
                     VRLCQLFYNFRKPRDHPLADARVRRALTYAIDGESLVRDVLTGSAEQAAGVVPLSLQGA
                     ERTGSFVHDPARARQSLKSLGADGLRIRIMWESGEFAADTSVMEAVAEMLKDVGVRTSL
                     LQFEPGGDILKWRQGKGGDWDVIGNGFPGPTGQAVTMLQAMYAGTAEDERTGDAFMGYV
                     DPAIARRISDAATEADPAARDRELAAAQHAVWDTWPCLWAFVPKTLLARRTRVEGIGLL
                     PVNSYDLTAVRLEG"
     misc_feature    39713..39729
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.97"
                     /tool="antismash"
     gene            39919..42276
                     /gene="pdxA"
                     /locus_tag="IE325_RS23050"
                     /old_locus_tag="GCM10018780_46590"
     CDS             39919..42276
                     /EC_number="1.1.1.262"
                     /GO_function="GO:0050570 - 4-hydroxythreonine-4-phosphate
                     dehydrogenase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pdxA"
                     /inference="COORDINATES: protein motif:HMM:TIGR00557.1"
                     /locus_tag="IE325_RS23050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_46590"
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase
                     PdxA"
                     /protein_id="WP_190071902.1"
                     /transl_table=11
                     /translation="MSFTSRDAPTRPADAGARVTPPHPDARIRPSAADTRTPRPVLALA
                     DDLSGAAETAMALGLPGRIVLGPAPSAPPGEGDAVVVDLDCRGVPPDEAARRVREALRT
                     VPDGALVLKKADSLLRGNLAAETAAFTDGAEGVVVTVALPALGRTVREGVVHLSGVPLH
                     RTDAWRAEVTGPPTSVAAALGDSRTAVVPLAAVRDGALPRVLRDTIAAGRLPLCDAETD
                     ADLDRIADAAIAAGPGVRLLGTGGLAAAVGRLLGRTGGASAPAGTPVRRERRPLLIVVG
                     TAEPAAAAQIAQLAQRGARHIALPADRLSTTDGHAAGTSDVTVLSIDNGQRVQPGSAYR
                     PVHGLARLAAHHAAGADLVLTGGETARRVLDALEVPQLTPLGEIHHGAVHALASDGRHV
                     VTRPGSFGETDSLLRIAAALRPDRFRTPPLHIPTPDLPPQGDPLVNATPTTGDRRPLPL
                     IAVTMGDGAGIGPEVIVPALLHPDTLARCRPVVVGDAERLRRAAAILGVDCDIVAVAAP
                     EEAEFRPGRVNVVDLGLIPADLPWGELSPVAGDAAYQYVRVAADLAMKNAVHGICTAPL
                     NKEALHAAGHLYPGHTELLAHLTGVDEVSMMLSTPKVKVIHVTTHIGLIDAVRRIEPGL
                     VERTVRRGHEAMVRAGVAQPVIGVCGINPHAGENGLFGYGEEEEKIVPALEILRADGID
                     ARGPLPADTAFFLAGRGDYDLIVAMYHDQGHGPVKVLGIEAGVNLTVGLPVIRTSVDHG
                     TAFDIAGKGIADAGSMVEALRQAAEMSSVPAP"
     gene            42344..43174
                     /locus_tag="IE325_RS23055"
                     /old_locus_tag="GCM10018780_46600"
     CDS             42344..43174
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006129984.1"
                     /locus_tag="IE325_RS23055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_46600"
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="WP_190071903.1"
                     /transl_table=11
                     /translation="MSPTGSQARRDRILHLATTTGLTSVEELSQRFGVTASTIRRDLAK
                     LTADGRLARTYGGAMALTAHPEASLRQRTGEAFEAKRAIARRAAAEVGAGETVLLDAGS
                     TVGALAHELRSAKELTVATTGLTALQELADVETVHVECLGGTLRPLSQGFVGPLTEAAL
                     EHMTFDRVFLGTDGISPEHGICEADLRQTRLKELMARRADHVYVLAHAAKLGRRPFHAW
                     ATLPEGWTLITDPDADPATLDALSERGVEVVLAEVPPPAADYPAPPTGSGAPDA"
     gene            43167..43853
                     /locus_tag="IE325_RS23060"
                     /old_locus_tag="GCM10018780_46610"
     CDS             43167..43853
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (7-162). E-value: 1.4e-12. Score:
                     39.9. Matches aSDomain:
                     nrpspksdomains_IE325_RS23060_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056764.1"
                     /locus_tag="IE325_RS23060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_46610"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_190071904.1"
                     /transl_table=11
                     /translation="MPEPRHALVTGVSSGIGEAICRRLLQDGWRVTGISRRRPVPAPGL
                     TWLRADLAEPATLNRTLDGIAAPDAIVHAAGLQRSAPLGELSADDGELMWRVHVQSAVI
                     LLDRLAARLPDGARVVLVGSRTATGVPGKSQYAATKAALPALARSWAAELAGRGITVNV
                     VAPGPTDTPMLSDPGRARTPVAQPPLGRLVTPDEVAGLTAFLLGPEGGAITGQQLVQCA
                     GASLSR"
     CDS_motif       43188..43247
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS23060_0001"
                     /evalue="2.20E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE325_RS23060"
                     /protein_end="27"
                     /protein_start="7"
                     /score="10.7"
                     /tool="antismash"
                     /translation="LVTGVSSGIGEAICRRLLQD"
     aSDomain        43188..43652
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS23060_PKS_KR.1"
                     /evalue="1.40E-12"
                     /label="IE325_RS23060_PKS_KR.1"
                     /locus_tag="IE325_RS23060"
                     /protein_end="162"
                     /protein_start="7"
                     /score="39.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="LVTGVSSGIGEAICRRLLQDGWRVTGISRRRPVPAPGLTWLRADL
                     AEPATLNRTLDGIAAPDAIVHAAGLQRSAPLGELSADDGELMWRVHVQSAVILLDRLAA
                     RLPDGARVVLVGSRTATGVPGKSQYAATKAALPALARSWAAELAGRGITVN"
     CDS_motif       43512..43640
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS23060_0002"
                     /evalue="1.90E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE325_RS23060"
                     /protein_end="158"
                     /protein_start="115"
                     /score="1.3"
                     /tool="antismash"
                     /translation="GARVVLVGSRTATGVPGKSQYAATKAALPALARSWAAELAGRG"
     gene            complement(43897..45018)
                     /locus_tag="IE325_RS23065"
                     /old_locus_tag="GCM10018780_46620"
     CDS             complement(43897..45018)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010056793.1"
                     /locus_tag="IE325_RS23065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_46620"
                     /product="sensor histidine kinase"
                     /protein_id="WP_190071905.1"
                     /transl_table=11
                     /translation="MSGARGAWWARIPEPVLDAVVVVVAVVDVLINLDDTSGPAWAMAT
                     LACAALIVRRRFPLPVFLLTLPASLMLDIVFAPFAALFTLSERSRDRRLLVTCALLFAV
                     ASATPWPLDDLSSHERAWTLVYFFYTLATAAAPVLLGQLVQARRDLARRLVEIEEAREH
                     ERLLHSQAVLARERAQLAREMHDVVSHQVSLIAVQAGALQVAAKDPDFREGARTIRSLS
                     VDTLDELRHMVTLLRASGGRSTELTPQPTLADLHKLVTTSGIDAELTGELPPDVSSTAQ
                     RTIYRTVQEALTNVRKHAPGATATAHLWHDGDAFGVTVTNTPPARPSLPLPGSRQGLIG
                     LKERAELLDGTFASGPTGDGGYEVRLRIPNRAG"
     gene            complement(45015..45689)
                     /locus_tag="IE325_RS23070"
                     /old_locus_tag="GCM10018780_46630"
     CDS             complement(45015..45689)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010357743.1"
                     /locus_tag="IE325_RS23070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_46630"
                     /product="response regulator transcription factor"
                     /protein_id="WP_190071996.1"
                     /transl_table=11
                     /translation="MVVDDEALVRSGFDLILSAADDIEVVATSVGAEAVDTVRRERPDV
                     VLLDIRMPDVDGLTVLGRLRALPEPPVVAMLTTFDADEYILTALRSGAAGFLLKDTEPD
                     QLAQLVRTLVAGGVVMSPKASRAVWQNHPGAAVVDDEDSTRVGRLTEREREVLVLIAEG
                     LSNADIGARIHLSAGTVKDHVSAILTKLRVGGRVQAALLAQRAGLLDEGQRDGEAGPGS
                     GR"
     misc_feature    45688..45701
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     misc_feature    45750..45763
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.17"
                     /tool="antismash"
     gene            46050..47291
                     /locus_tag="IE325_RS23075"
                     /old_locus_tag="GCM10018780_46640"
     CDS             46050..47291
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998604.1"
                     /locus_tag="IE325_RS23075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_46640"
                     /product="DUF418 domain-containing protein"
                     /protein_id="WP_190071906.1"
                     /transl_table=11
                     /translation="MTQNAEDTVLAVRAPTRPEMATRTPAGVPESGRASVGRLVGVDLA
                     RGLAVFGMFAAHVGPDPSQGGITGNLMELAHGRASALFAFLAGFSIMLITGRRTPRTGR
                     AGREAVAKVVIRALVLLALGTALTMTGTPVEVILAFYGLYFLLVLPLYRLTAGPLAVIA
                     AGTSLVLPQVLYVVKQALPAEGVDGVWAWPADADGIVSLLFTGSYPALTWIPFVIAGMA
                     VARLDLAATAVRIRLAVTGVLLAALGYGGSWLALHLVPGAMTELGAVSWGGAGSVSSAW
                     WSDTWGFPYDSTTAGLLVASPHSETTLSILANTGVALAVLTACLAAVDAWPRFHRLARP
                     VIAVGSMSLTAYVLHIVGIRLLGIEELPGAALHVLLGFIVAITVFAALWSCRFRRGPLE
                     WLLGKATKPAELVR"
     misc_feature    47650..47665
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.37"
                     /tool="antismash"
ORIGIN
        1 aggcaccggc accacgggcg acacggttct gtcggatgtc ccggaggcga cgcaggatgg
       61 atctgctcag ccttcgcagt ccccggagac cacgccttcc cccgaggcgc cctcctctcc
      121 cgagacgact ccctcgccgg acaccgccga ctcgtccgac ctcaccaccg ctccgccgaa
      181 ggtgagcacc accgggtcct acaccgacac cggcgacatg tcccaggcgc cgccgctgac
      241 gatcgtcgtc tcggaggtgc cgccgcccgg ggaggggtcg ccggacgcga tcgacctgct
      301 ggaccgggcc gggaccgacc gtgccgtggt gctggggccg gcggtcacgc cggacggggc
      361 ggggcgcccg gtgcgcgccg ccgtcgagct gacgcgggag ggaccgggca ccccggtccg
      421 ggtgcgcccc ctcaccggcc cggcacccac cccgacgccg aacgacaccc aggccaccac
      481 cgtcaccacg gtcaccaccg agacggcctt ccccggcgcg gacatcctgc tgccgctcgc
      541 cgacgccctc ggcccggcgc cccacccggc cactcagagc accgcgacaa cagacagcga
      601 cccggcgagc gacaccacca ccgccccgcc gcccaagaag atcctcaccg agtccgcaac
      661 gcccgtaccc agcaacggaa tcgccccgga ttccacggtc accaccaaca agctcgccac
      721 cctgtcccgc ccctggaccg agacggccac cgacctgcac ctggagtcgg accacggcaa
      781 cgcgcccggc cccggtgcca gaccctccgt ggcacccccg ccgccgggac gagtcatcgt
      841 gcgaccgacg ggcaacgcgg acaaccaacc ggccgtcacc accctcgacg gccgcacggt
      901 ccccctcaca caactgcgcc gctgggtacc ggactccgcc gtaaggcccc ggccggggcg
      961 ggccgtccag acgctgacga tctcgcagag ccccgccgag gacggtacgt cacgtgacgc
     1021 gggccgaagg gcgctgctcg gtcaggacac cttccgcggc gtacgcacca cctcggggcc
     1081 gtcctcgtcg gacccgcccc gcacggtgtt caccggcccg ccgaccgcgc tccccggctc
     1141 gggtaccgag cagggagccg actacttcgt ggggcacggc acccctcgca ccgtcacgct
     1201 cggcaccgac gacgcggcgc agcccaccgt gaaggtcagc ggtgtgcagc tcggcgaggt
     1261 gctcaactcc tgggcgcagg acgacgatca ggggcgtccg ctggtgctgt tctcctgcga
     1321 gacgggacgg cagccggaga tcgcgggact gcccgtcgcc cagcacgtgg cgaaccgcac
     1381 cgggcggccg gtgtacgcgc cgaccagcga ggtgggcacc gcccgggacc gggacggtga
     1441 cgtccgcgcg gtgctcaccg agggcccgga cgggccggga cgctggcggc tgttcctgcc
     1501 cgagcccggc ggcgccgaac tggacgacat ggcacgtgac gccgggctgc acaccggccc
     1561 ggaaccggcc gacgccttcg cgcgtgcccg caccctccag cagatccgca ccctccgcga
     1621 cgccctgggc ccggacgccg aacagcggcc ggagaaccgg gagttgctcg ccgggctggc
     1681 ctatgtcgac ggtctgcgct ggctcagccc ggacaacgcg gcccgctacg gcgacggccg
     1741 gatgacgccg gacctgttgc gccggatggt caccgaccag cccggcgccg gggtcgatcc
     1801 ggccaccggg cccacgaccg agcagtacac cgaattcctg cgcgccgcag ccgagttgcg
     1861 cgccaccgcc ggccccgaca ccaccctcga tgccctgctg cccccgccgc ccccggccct
     1921 cccgccgggc accctcgtct cgccggagga cgtgcgcggg ctcacctacg cgccctccgc
     1981 gcagatcacc tggtcgctct ccgacacccc gctgccgctg tccgagctcg gcctgaacgc
     2041 cgaggacacc gccgaactcg cccgccgcag acccgatctg tcgcccgcgc cgagccgccc
     2101 ggagagcctc gccgaggacc tgaacctctt cagcaaggac gccgcctccg ccgacaccgt
     2161 gcgcgcggac ggacggaact tcaggcgcct ggacaccccg ggcggcggca actgcctgtt
     2221 ccgggcgctg ctcgactccg cgcgcggcca ggacgtaccc ccggcttggg ccgcgcggaa
     2281 cgtcgccggg ctgcgtggcc tgctgcgtga ccggatcacc gggtccgaac tggccgccgc
     2341 ggcggccgag gccaccccgg acccggtact cgccgtggtg gacgacctgc ggatgaccgc
     2401 gctcgccggg gtactgaacc ccgacgcccg gagcaggatc acccagcgct ggaaccgcat
     2461 cgcgcagacc gtcgtcaccg acggcgacgg gcgccagtgg cggcgcatcc tccgtgacag
     2521 cggctacccg cagctcgcca ccgtcgcgcc caccccggct gacgcacggc gactcggcgc
     2581 cgagggactc atcgccgccg cggccgaaca ctccgccctg tggtcgtccc cgttcgcaga
     2641 cctgctccct caggcgctgg cgcacaccct cgacctcgat ctgcgcctcg tccgtcccga
     2701 cctgctcgca gccgggaagc ccgtggtcgt cactctccac ccgggcgggc agggcggcac
     2761 cctgcacctg gcctacaacg gcaccgacca cttcgacgcg ctgatcccgg ccaccgcccc
     2821 gctcaccgcc gtaccggacc ccgtcaccac ctccggggac ccggccggcg tcgagcccga
     2881 cggctccgac cccttcggcg agtggctgcg cggcatgggc gggatcaccg acctcgacgg
     2941 ccccgacgcg gagaccccag accggggcga cccggtgccg ctggagaccc agctcgaacg
     3001 gcaccgcccg gcccgtctgc tgaccggtcc ggacgcccag ccgcccggac cggcaccacg
     3061 cgacatcacc ttcgaggacg gcagccgact gcccacggtg ctgatcgacc cgggcgccga
     3121 tccggatccg gccgacggca gcacgcatgc acccacggac ggcaccccgc cgagccgccc
     3181 gaccggtctc ttcaccggcc ccggcgtcct caccctgcgc tcgcccgagc aggtcgccga
     3241 gcagatcctc gggcaactgc cgaagaagct gcgggaccag ttcgacgagg cggagctgct
     3301 gcgcctgctc accgaccagc ccggcgcctt caccgccccg cgcggagcgc gcttcgtggg
     3361 ccgggagaag tccggggtcg gccatgagat gacggtcgag gccatcccgt accaccgctg
     3421 ggaacgcttc tccgacgtcg acggcggcac cacccgcctg gacaccatgc ggcgcggcca
     3481 ggccggtacg ggcggtgggc gcagcgtcgg cgtcggacgc cgggtcgcgg ccgcgctgag
     3541 catgggcccg ccgctcaact ggctgctgaa gatcggcgtc tcgctgggct ggacccgccg
     3601 taccgactac tccctgggca cccaggcgta ccaccagacc gagtggcgcg cccacgaggg
     3661 ctcacatctg cacctggacg acgtccacta ccgggtacgg gtggagcgcg tcaccgaggc
     3721 accgaagggc acgacgcccg cgacgggccc gagttggcgg cggagccagg tgcacaccgc
     3781 gcagttcgcc atgcgggacg gcctgagctg gcgactgccg gacgacctca ccgtgccgta
     3841 caacggaccc cgcagggcgc cgcagaggct caccttcccg gacggggtcg agccgcggat
     3901 gaccgacacc accggactgc acctgctgga cccgcccgag gacatcgcgc tcgccatctc
     3961 cggcgcccgg cccggcagtt cggcgcaccg cacactcatc tcgtacgtcc gtccggggcg
     4021 gttgctcgcc ctgttcggcc gcttctccgg gccggtgagc gggcccgagc tgacgcgggg
     4081 gagcgggcag catccgctgg ggcacctcgt cgtcgagcgg tcgatcccgc agcgggccac
     4141 cctggtcgcc gagtcggtca aggcggagct gcgcgacctc acccagacca cgtaccagaa
     4201 cgaacgcggc catgtccgcg acacccgctt cggcgtccag gtcaccgccg gacccaacta
     4261 caccctcgtc ggcccggaga cggacgtacg cctccagggc gggccgctcg tccgcgcgga
     4321 cttcagcacc gggcacggcc actacctggg caccgacgcg gcccgcaaga ccaccggccg
     4381 tgtccgcaac caccccgtcg cgctgtaccg ggtggagcgc accctgatgg tgcgcaaggc
     4441 cggcgagccg gcttccgcgg cccgcccggt gcgggtggtc agcctggact ggatctccac
     4501 tcaggacgcg cgccgcctcg cgggctggga cagccgtacg cccggacaga cgggccccaa
     4561 cccggacgcc gaaccgccgg tgccctggta cctcacccgg gaggacccgg tccacctcag
     4621 cggccaggtc cgcgccgagg gcttccggcc cgaccggccg cagaacgccg tacccgacca
     4681 gcagcagaac caggatgggc aggccgcccc tcaagacccc ctgcgtgcct tcgcggacac
     4741 cgtcctcgac accctccacc gctcctaccc gtccctcttc gtcccgccgc tgatgctgcg
     4801 ccacccacgc ctggcccggt tctggtacgg cgacgggcgg atgcggaccg cgttgcacaa
     4861 cgaccggcag gtgcgcgagg cgctcaaccg gcccagcctg gcgcagagtc tggacgacct
     4921 gaccaccacc ggcgtgccgg tcaccctcac cgaggacggc aaggtgagcc gcggccatca
     4981 cacgctgatc ctgcgggcga ggctcaccga ccggcggttc gagaccacca tgagcgaacg
     5041 gtcgctgcgc aacgcggtga tcggcaccga ggtctccggc cagggacagc aggcgtccac
     5101 gaccctgtcg ggtggcgtcg agctgggcat ctccccccgg gaccacgaca aggtgccgga
     5161 ggcggggctg ccgcgccaga ccggcaatgt gtccctgggc gcccgttacg ccaagacgga
     5221 ccagaaggcc acccgcagca cggccgcggt cacccacgac cacctgatgt tccagaacgg
     5281 cgccggcctc tacagctacc aggtggaact gggcgcctcc ttcgagggcc accgccgccc
     5341 tcgcggctgg gcccggctcg ccacggtcgg cctcctcggc gccggcgtct tcgtcagcaa
     5401 ggtcgaggag cgcccgctgt tcagccgggg caacgagacc gtgggccgcg tggaactggc
     5461 cgtgcccgcg gcgcacggct ccgaccggca cgcccccgcc gacccgccgc ccaccggacc
     5521 ggccccggcg ccgcccgcac ccataaggct ctcagccgtc gaggcggacc aactcctcga
     5581 cggaacacgc ccgttgccac ggaccgactc ggccggacaa cggctcgtcc gcaagctgct
     5641 gcgcgccccg cacgtggtgc tcagcaccga gggcggcggg cagcggcagc aactgatgca
     5701 ggacaccgcc gacctggcgt cgggcacctc ctggcatgtc agcgcgcccg gcgccccggt
     5761 gcgcagcgcg ctgcgccggg cgatggccaa cctccatgtg gccggtcaac tcggtcagta
     5821 cctgggcccg ttcggctccc gcatcaccgg actcaacggc gcaggaccgc tccagaccca
     5881 ctacctcaag gccgcggtcc gcggcgaact ggacaacctg cgggtcaaga gcgagccgaa
     5941 gccggccagc ctcgaagcga ccatcggcaa cgaacaccgt gtcgccggca ccgcgagcac
     6001 cgtctcgcgc accaccctcg gcgtccaggg cgccgacatg ccgctccagc aggcccccgg
     6061 cggaccggcg gtggtcggct cctactcgac cgccctccag tacgcctggg gcaagggccg
     6121 cggcgtcgcc cagaccctca cccggggacg caacaccacc ctcacctacg ccggtcggat
     6181 gtacctggtg gtcgccgacg ccgccgagac cgtcgccgta cgggaccggt ggacggccgc
     6241 gatgggcgcg gtgggcacgc gcgccggggc cggtatcagc tccgccgccg gacggatctc
     6301 cgagcgcctc ggccgcgcac tcgccccgcg ctcggccgcc gccacgctcc aacgggtgcg
     6361 cgacgcggtg atgttccacc tgcccatgca ggacgtcatc gaggccggac tcgcccccga
     6421 cggcctgggc accaccaccc cgcgcaacct cggccgcggc taccgggtgc cccccttcct
     6481 gcgcgggcgc cgcttcccca gccaccccag cggccagctc gacgcgagcc acgccgcaca
     6541 gcagctcatg ggccggctga cgaagatcgg cgtgtcctcg cacgaccggg agcaggtgct
     6601 gcagcggctc tcgccggact tcctgcgcgc ccatctgcac gagctgacga ccgacgggat
     6661 gaccctgccg gtccgctacc gcaactggac cagcccgacc cggctgccgg tcggcggcag
     6721 ccccggacag gtccggttca agctgacccc ggtcaccacc accgtggaac ggctgcgcac
     6781 cggcttcgag ttggaggact accgcaccac cgcccgcgac gactccgccg cttcctccca
     6841 ggaccgcggc gccgatgtca cgcttgccac cggccagcgc gcggcggaga gcggcgtgct
     6901 gctcgccaac ccctcgctcc agggcaccgc agccaagcag cgttcgagca cccggaccga
     6961 gaccaccggc aacacctcga tgccgaacat cgccaccacc caggcgcacg ccgagatcgt
     7021 caccagctac gtcctgaccg tcacgatgac ggacgcgacc ggcgagctgc tgtccccgcg
     7081 cgccgtggcg tcggtcggct ccctcaacga gatcgtcccg gccggtctgc tcaccccgga
     7141 cgacgacggc gcgctcaccg aggaggacgt gcccgaaccg gagcgcgcgg tcaagatgct
     7201 gacggccgat caggcccgcc cggagggcat cgcccaatgg cgcgacggca ccgccgaccc
     7261 ggacgtgctc cccttcgacg accgcatcgg ctccggcatc ctcgccgtgg acatccgcgg
     7321 cgcggccaac gtccaggacg ccctcaccct cgccaccgcc cgcgccgacg gcctcggcga
     7381 cagcgacctc ggccgtcgcc acaccggaaa cgtcctcgcc gaacgcgtcc gcatggccca
     7441 cctcaccccg ctcaccggcc tcggcaccgc ccccgcgcag gcccagcagg aggccaccac
     7501 ccaggtcggc ctgacttccg gcttccgcga ggcgctcggc gcgaacggct cacagctgcc
     7561 cgcccaggcc tccgcccgcc tcttcggtca gtcccacacc gccgactccc gcctctacgc
     7621 gaagatgcac cgcaccggcg cccgcctcct cgccgtcgag agcaagcccc gaatggaggc
     7681 catgcagcgc tcgaagacct ccgacgcgct ggaggccggc atcaccgaca acgtcgaggg
     7741 cgtggtcggc acctcaccgc tcgcgggcaa cagcaacgcg ggcgtcacca acccgggcgc
     7801 ctcggtcccc atcggcggcg cgaacgacgg caccgccctc aagggcaccg ctgacaccac
     7861 cctcggcacc cacctcaagg tcgtcaccga ccgcagcatg ctcttcgcga tccccgtgag
     7921 ctggctgtcc gtggccgaag tcgaccaccg cctcaccgac agccgtccaa tgcacgccct
     7981 cggcaaggcc aagcgcggcc cgcgcgccgc cgaggccgag accaccgccc tggtctggct
     8041 gcgcgaggac atcgcccgcg actacggcct cctggacgac accacgttcc ccgacgaggt
     8101 cggcgcggcc tgggacgcca tggccaaggc ggcgggtgac ctggccgcgg ccgagaagaa
     8161 ctactacgac gcccgggcgc gggcccgcga gacctggctc gacctcaccg cggaggagca
     8221 ggccgcgctc ggcgacgacg accccgacag gccgaccgtg ctgccgcagg ccgtggccca
     8281 gtccccggcc gtcgccgcct ggcaggccgc acgcgaggag gtccgccgct gggagggcca
     8341 caccgacacc gccgccgcgg accaccaccg gctgcacctc gccgcctccc gcctcaccgc
     8401 ccaccaccag ggccgggcga cggtcccggt gccggacctg gcacaggagt acaccgaacc
     8461 ggcctggaag tccgaggcgc ccgagccgta cgagatcacc gacggggcac cgcgtactct
     8521 cacctccccg gacggcacca ccgtgcgcga agtgcacgac atgccgcacg acggcgcctc
     8581 gttcttccac gcgctcatcg ccgtggccca ggaccgaggc cgcttgcccc acctcctcgg
     8641 caccgacctc gcggccaggt tcacggcgaa ccccggcgac ccggcgatca ccgaacgcgc
     8701 ggtccgggcc gcccgcaacc gcctcgcctg ggaactgggc gagaaccgca acgaggacct
     8761 cctcgacacc ctcgccctcg acgccgcgga caccttcacg caggacgaac tcgacttcgc
     8821 ggaggtgcgg ttgacggccg cccagcaggc cgagttcgac gcgttcggcc gtctgccgca
     8881 gacgttctgg gcgtcccccg agcagcgggt cgcgctggct acggcggcca tgctccgtcc
     8941 gttcaccagc gagccgccga ccgggcgccc ggacggcgaa ccgaccccgc cggaacgccg
     9001 agccggcgac cacggcggcg ccgacctgct gcccgccctc gccgcccgcc tcctcggcac
     9061 gccggtcacg gtcgtgacgg gagagggccg cgagcagcgc ttcctgccgc acggcaccga
     9121 cccggccgcc gtcgacccgg cccgcgatcc ggtcctgttc gcggccgacg ggtacttcca
     9181 cgccgcgctc ccgcccggta cgccgccgcc ggtcgccacg ccgctgccga cgcgggccgg
     9241 taccagtacg gccaccgaag ccggccctac ggatgcccac cgcagccatg ccaatccgcc
     9301 ctggcacccg cccgcggaca gcaccggccc gcgctaccgc cttgcccgcg acggcgtcct
     9361 caccgcaccg gacggcgcca cctacaccca gggcgctccc gccggccgcg gcaacggctt
     9421 cttcgccgcg ctctccaccg ccctgcacca cgccgccggg cagcccggcc gggaccgcaa
     9481 cgaagcggca cgactgcgcc tgcgcgccga cgcgccgccc gcccggctca tgcgcctcaa
     9541 cggcctgccc ggcgcccggg ccgaccgcga ctcgctcttc acaccgccac ccttcacggg
     9601 ccgcccgggc gcgccgccgc cgagccagga cgccctcgac ggccatctgc gccgctacct
     9661 cgccgacgcg ccctggggtt ccggggcgga ccgggcggtg gcggagtggg ccgctggggc
     9721 gaccggcacg accgtgaccc tgatcgagga gaacggcacc gcgcacacgt accccggccc
     9781 gtccggcgag tccggcccgc acgtccggct ccgccgccgg ggtggggact tcgtgccggt
     9841 gatcctgcgc acgccggcac cggagccgac gccgcagcac gaggaccccg cgtccgtccc
     9901 gttgcccgac tcccccaccg gcagcgccct ccccggcctc cctggcgacg aggaggcgta
     9961 cgaactcagc acgctgtctg gagcgaactc gacctcggac atggagatgg acctcgactc
    10021 cgacagcgag caggcggccg tactcaccgg cccggagcac gagttcgcgg ccgagttcgc
    10081 cgccctgctg gaggagcccg aactgcgggc cgacgccctg ctggacgtgg tgcgacggcg
    10141 caacgcccag ctcggcggct tcccggacgt ggcgttcgac agcgcgttca ccgagcacac
    10201 ggggatgggc gtacccgagg cactggacca ggtggagcag gccggacggc tgtcgagcga
    10261 ggagtacgag gcgctgcgcg aggcactcgg cctcggcacc ggcctcccct tcacccagac
    10321 gaccccgacc ggcacctccc agcgcgaccg cgaggtgacg ctgcggatgc tggaccgggt
    10381 cgcccgcctg gtgaaggaag cgctccgcaa accgaaccgc caggccgacg cccaggtcac
    10441 cccgcatatc gccgtcaccc tgctcccgga cggctcgctc ggcatcgccg gcaacaccgg
    10501 cctgaaggcg ctcaccgccg acgaggcggc cctggtcgag gacgaactgc gctggttcgt
    10561 ctccggacag gagccgggcg gcacccggcg ggtgcgggaa ctggagcagt ggtccaggga
    10621 cgaggagtcg caccgggagt ggtcggcgcg gctggaccag gagcagcggg acctcgctca
    10681 acgcaacgcg gaacaggcgc agttgagggc ccggctggag gagcggtacg agtcggacgc
    10741 gtgggacgaa ggacttcagc agcagtggga caccttgctg gaggacgaag cggccaccgg
    10801 ccaggagcaa cagcgcctga ccggcgagcg gcagcagtgg cgacgcgacg agcgctggct
    10861 ggcgcgcaga cggcccggca tcgcacgcga gacacgcgac cgtacgaagc tacgcgccct
    10921 cgccaccggc tggtaccgcc tctaccaccc ggactcaccc gaactcgacc tagtcaagcg
    10981 ggcgttggcg aaccctcgca tcctcaacgt ggcgggcttg gacggttcct cggcgcccgg
    11041 ctcgcacggc tccgaacacg gcgagctgac cttgctcgga cactgggtcg agcactggga
    11101 gaacaacccc ggcgacccga acacgcccca gacgctgccc ctgggcggct tcaaaatggc
    11161 ctgcgcctcc tgcgacctcg cctaccgggc ggtcaaccag cacatcggaa gcccgctcgg
    11221 ccaccgcgtg caggcctccg gcactcacgg aatgttcttc cccggctggc gcatgccgca
    11281 gtggatgcgg caacggcccc aactcgtgca gtacatcagg gacaacgcgg agagcatcgg
    11341 cgcatacctg gaccagggcg gcgtactcca gggcgacagg accgagggca cgcacgagca
    11401 gtaccccgcc gggtcctcgt ccgagtacga gtccggcgac gaggccatgg acacggacgc
    11461 cgtgctcggc tccccatcgc cgggcacgtc cccgcggctg ccgcggaccg ccccggccga
    11521 gcccgtcgcg accccaccga caccacaagg cccccgcgac aaccgccccc gcttcgtggt
    11581 gcgttccggc ttcgacgccc gccggttcac gtacggcggc gaaccggtca ccgacctcac
    11641 gatccgcctc gcgatacggg gtcccgaggg ccaggccgca cacgttcgcg atcaactcgc
    11701 cgtaggcgtg cgtgagttgc tcaacaaccc ggcctaccgc ctacccaacg gcgatcacct
    11761 ccacatcacc gtcgaacacg tcgaccccgc cgactcaccc cacctgaccg tggacctggc
    11821 gggcagggac cgcccgatgg accagaacac ctggtgggcg gacgccgacc cggcccacct
    11881 cgtccacgaa ctcacccacc agctgggcct gcgagacgaa taccgtgaca ccgactcccc
    11941 gcaccgccct cacatccctg gcagcctgct gggcgctctg gacgagcagc cggaggacac
    12001 gtcgctgacg gccgcaggcc tgcgtgaccg gcacctgtcc ctgctgagcg ccctgatcgg
    12061 tgacgtgccc ccaccaaccg ctcagcccga cgaccagacc tgggaggccg cccgcacggc
    12121 caccacgccc acccctcgca agtcggtctg ggtggacccg gtctccctac cccggtccga
    12181 atccgaagag cccgacgtcg cggcccgcat gccgcaggca gaagcgacgc tcactccctt
    12241 cacgtcgggc aacttcgagt tcaccaacct caagcacacg aacgagaagt accgcgacaa
    12301 ggccgtccgt atcatcgatc tgctgcgcaa gcacgacacg atccgcgcct tcataggcac
    12361 ccgcccttgc cgcatcaccc tgcatctgcg caccacggag accccggccg atgtgacgga
    12421 tcacggcgat cacgtcgaga tcaatctcgc gagctactac ttcgagaagt acgacatcgg
    12481 ctacgtcatg ggcatgctgg cgcacgagat cggcctgcat cccctcgctt cccagaacac
    12541 gaacatcccg gacgaggagg ccatgttcga cggtgtgccg ctcgccgttc ccgggctgac
    12601 ggacctgaag actccgcgca ccatgagcac cgagggcgcg ggccaggccg accacatcat
    12661 ggccgccttc cccagcagca cccggcacgg gatctaccgc gacatcgtcg tggggatggc
    12721 gggcgtactg gccggggacg cccaggcggg ggaggagggc gccaaggcca gggacgtcac
    12781 ggatctgatc gacacctacc tcatggacct ggcgacgatc gccgtcacca acgaccgccg
    12841 caaggacgcg gcctgggaac cccgctacac ggcgaaggtc tacaacgcgt acaaggagat
    12901 gttcgtcgcg cagctgcccc aggacagtcc cgtccgcgcg ctgctgccgg cggacaagag
    12961 ctggtacaac gtcaccggca acttcctcgg cctcggcagc agcttcgcct tcaacaacca
    13021 gggcgacagc atccagaccg gcaccgaccc cggcgaggcc cgcccccggc ttcctcagcc
    13081 aggcaccggc acagcgccgc gaccgacgaa ccggccacag cgtccgcgag acaaccgccc
    13141 ccgcttcgtg gtgcgttccg ccttcgacgc ccgccgcttc tcgtacgacg gtgagccggt
    13201 caccgacctc accgtccgca tcgccatgcg aggcaccgac gcacaggcca cgcacacgta
    13261 cgaccaactc acggcaggcg tccacgagtt cctcaacaac cccggccacc ggctccccaa
    13321 cggcgatcgc ctccacgtca cggtcgaact ggtccggccc acggactccc cgcacctgac
    13381 cgtggacctc gtcggacgcg accggatcat ggaccagaac acctggtggg cggatgccga
    13441 cgcggcccac ctcgtccacg aactcaccca ccagctgggc ctgcgagacg aataccgtga
    13501 cgccgactcc ccgcaccgcc cccacatccc cggcagcctt ctcggcgccc tcgacgagca
    13561 gcccgaggac gcctcactca cgcccgcagg tctacgcgac cggcacctgg ccctgctgag
    13621 cgccctgatc ggcgacgtgc tcccaccgac cgctcagccc gacgaccaga cctgggatgc
    13681 ggcccgtacg cacacgacac cggtcccgcg tcggtccgtg tgggtcgacc cggtctccct
    13741 acccgggtcc gaatccgaag agcccgacgt cccggcccgt atgccgcagg acgcgacgct
    13801 cacccccttc aagtccggca agttcgagtt cacgaacctg aagcacaccg acgagaggta
    13861 ccgcgacaag gccgtccgca tcatcgaact gctcggcgac cacccgacga tccgcgactt
    13921 catcggcacc cgcccctgcc gcatcaccct gcatgtgcgc acgacggaga ctccggccga
    13981 tgtgatcgac cgtggcgatg tcgtcgagat caacctcgcg agctactact tcgagaagta
    14041 cgacatcggc tatgtgatgg gcatgctggc gcacgagatc gggctgcatc ccctcgcctc
    14101 ccagaacacc aacatccccg acgaggaaga gatgttccgg ggcattccac tcccggtgcc
    14161 ggggctggcc gacctgaaga ctccgcgcac catgagcacc gagggcgcgg gccaggccga
    14221 tcacatcatg gcggccttcc ccagcagcac ccggcacggg atctaccgcg acatcgtcct
    14281 gacgatggcc gacatgctgg cccgggccgc gcaggccggc gtggagggcg ccaaggccaa
    14341 ggacgtcacg gatctgatcg actgctacct catggacctc gcctccatcg cgatcaccag
    14401 cgactaccgg atgaacgcgg ccaaggagcc cggcaacacc gccaaggtct acaacgccta
    14461 caaggccctg ttcgcccagc acatggcagc ggacagcccc gcccgttccc tgctgcccgc
    14521 cgacaagggg ctgctcggcg tcgtacggga cttcgcccgc ctcgccacca gcctcgcgac
    14581 caacaaccgc ggcgacagca tccaacagcc catcccgtcg gacgaggccc accctcggct
    14641 cccgcagcgg gccgaggcga aggcagagca aatcccggcc gtcacacggc agttgagcgg
    14701 ggtacgcgac catcggccgc gtttcgtggt gcgttccgcc ttcgacgcgc gccggttctc
    14761 gtacgacggc gagccggtca ccgacctcac ggtacggctc gcgatacggg gcgagggggc
    14821 caccgtcgcc caggtgcgcg accgtctcga agcaggggta cgtgaattcc tgaacgaccc
    14881 tgcctaccgc ctgccgaacg gcgaccgact gcacatcacc gtcgagcatg tcgacccggc
    14941 cgacgacccg cacctgacgg tggacctggc gggcagggac cgcccgatgg accagatgac
    15001 ctggtgggcg gacgccgacc cggtccacct cgtccacgag ctcacccacc aactcggtct
    15061 gcgagacgag taccgtgacg ccgactcccc gcaccgcccc cacatccccg gcagcctgct
    15121 gggggctctg aatgatcccc ccgaggactc ctcgctcgcc gccgccggtc tccgtggccg
    15181 ccatctgtcc ttgctcggcg cgctcatcgg cgacgtgacc cctgccccac agcaggagac
    15241 cgagcagacc tgggacacgg cccgtaccgc cgccgtatcc gtcccacgca agtcggtgtg
    15301 ggtggacccg gtctccctac ccgagtccga gtccgaatcc gaagggctcg acgtccccgc
    15361 ccgcatgccg caggcagacg cgacgctcac ctccttcacg tcgggcaact tcgagttcac
    15421 caacctcaag cacaccgagg acgggtaccg cgacaaggcc gtccgcatca tcgagctgct
    15481 gcgcaggcac gacacgatcc gcacattcat agccgaccgg ccctgccgga tcaccctgca
    15541 tgtgcgcacg acggagactc cggccgatgt gatcgaccgt ggcgatgtcg tcgagatcaa
    15601 tctcgcgagc tactacttcg agaagtacga catcggctat gtgatgggca tgctggcgca
    15661 cgagatcggg ctgcatcccc tcgcctccca gaacaccaac atcccggacg aggaagcgat
    15721 gttcgaggga gtcccgctca ccgtgccggg catggcggac ctcaggactc cacgcaccat
    15781 gagcaccgag ggcgcgggcc aggccgacca catcatggcc gccttcccca gcagcacccg
    15841 gcacgggatc taccgggaca tcgtcgtgaa gatggcccag atcctggcgg aggacgcggt
    15901 gaacggggag gagaacgcga agtccaagga cgtcaccgac ctgatcgact gctatctcat
    15961 ggacctcgcc tcgatcgcgg tcaccaacga ccaccgtatg aacgcggcga aggagcccgg
    16021 ctacacggcg agggtctaca acgcctacaa gcaggcgttc ctggcccggt tggcggaggg
    16081 ttccactctt gaggcgctgc gggccctcct gccgtcggac aagagcatgt tcggcgtgat
    16141 caacgacttc cggcgcatcg gcacctacat cgcgatcaac aaccgcggcg acagcatcca
    16201 gcaggcggac gccacctgag ccgtggagcc ttcgccggca ttcccgtcag tcgaggtcgt
    16261 ggaggaaagc gacgagcgcc gccaagagtt cggccggatt gtcctcctgg accagatgtc
    16321 cggccccggg gatgagccga agctgtgcgc cggggatgag ggaggcgagt tcatgggcct
    16381 tggccacggg gatccaggcg tcgtcggtgc cccagcagac caggacaggg atgtcgatcg
    16441 tgccgtaccg ctcctggatc tcgtcggtgt agcgctggtc ggcctgtgcg atctgccggt
    16501 agaacgccgg ctggccgtcg tcgcccagcc atggctcgac gagccggtcg agggtcaccg
    16561 ggtgcagtcc ggggctgctc gccgaagtca cgtactcgcg caccagggcg cgatgcagcg
    16621 ccggcggaag ctgatcgaac acggcggagt gccggccgac caggcggaag aacggggacc
    16681 cccagggcgc gagggccacc gggtcgacga cggtcagctt gcggtatcgg gcgtcgtgca
    16741 gcaggtgcgc ccgcagggct acggcgccgc cgaagtcgtg ggcgatcacg gccggttcgg
    16801 tcagccccca gtgggtcagg agctcggtga agacccggcc ctgggcggcg agggagacgt
    16861 cctggccctc ggccttcgcc gaagcgccgt agccgggcat gtcccatacg aacacctggt
    16921 gatggtgcgc gagtgagcgg gcgatgccgc gccagacgta ggaggagaag ggtgtgccgt
    16981 gcagcaggac gacgggatcc ctgccggtct ccccgaaacg gtcccagcgg acttcgcctg
    17041 ccgtgctgtc gtaggtcttg ctcagcttcc agtcagtcaa cggtgtccgt cctctgatcg
    17101 tgggtgatcg aattgtggca gagacggacg gtgggcggct ggggagcggt ggaacaccgg
    17161 ggtgtcgagg aggcgcaatc gccgtggctc gggcgggagt tcggtgattc gcccggcgag
    17221 gcgatttcgt tcggcgggtg cgcgccgtgc tgcttggcca tgcccgcgtc agccacggat
    17281 acggcgggtg ccgtggcacg tcacgagggg gcgtggtccg gtctcagggg gagaacgacc
    17341 gtgagcgtgg gcgtgcggac gatcgagcag gtcgtgtcca ggtgccatcc cgtcttcgac
    17401 gtaccggctc tgcgcatggg gttcggccgg gacggtctcg tctatctcgt cgtcgggggc
    17461 cggcccgacg gacgtgcgtt acggctcagg acggacggct cggagcagac cctcgcccgt
    17521 gtcggctacg cggcgcaggc gatcaccgcg gacgcggacg gtgtgatcgc gaccgccgac
    17581 acccacttcc cgcaccggat caccttctgg gacccgaaga ctcgtcctcg gccgcacgga
    17641 ggcagacctg ccgttccggt cgccctgatg gggggggagg cgggctcact gccggggcat
    17701 gcgctcgatc gccaccatcg cggcatcgtc ccccagatgt ccgccggcat gccgcatcag
    17761 gtccttgcac aggtgagcca ggagggcgtc gggacccttc ccggccctcc cggccacacg
    17821 ttccgcgagc gggtagaagg tgccctcgtg gtcgcgggcc tcgatgacac cgtccgtgta
    17881 gagaaggacg atgtcgccgt cctcgaaggc gaactcctcc tcggacagct cgctctccac
    17941 gaactcggtg agacccaggg gcggtgccgg gtggcgcact tcgagggggc cgacctcgcc
    18001 gtgccgcagc agcaggggcg gcggatgccc gcagttgacc aggtgaagga ccagttcgtc
    18061 gtccgggatg tccagcgcgg cggcggtgat gaaagcctcg ccgcgatcct cggccgcggc
    18121 gtccagagcc gacgggtcgt ccaggtccga ggacacggtt ccctccagga aggccatgag
    18181 cgccggaagg tcggcctgcc ggtgggccgc gccccggaag gcgcccagca gcagggcggc
    18241 gtcaccgacc gcctccaggc ccttgccccg gacatcgccg atgacgatcc gggtcgcccg
    18301 ctccgtacgg gcggcggcat agagatcgcc gccgatctga gcctcggact cggcggccag
    18361 atagaccgac gcgatccgca gcggaccgac ccgctggggg agcggcttga gcaccacctc
    18421 ctgcgcggtc gtcgccaccg accgcagctg cttcagctcc ctctcatggc gctcccgcca
    18481 ggcggcgaag acggtcgcga acgccgacat caggatcagc gtgatcagct ggaacgagtg
    18541 gttcagatcg atgagggtgg tgcgcaccgt cgccaccacg gcctgggcca gcactgccag
    18601 cgcacccacg caggcggtgg tccgcggtcc tgcgaacgac gcggtgacgg cgggcgcggc
    18661 caccaggaac gggccgaggt ggacgttgga cggagccagg atgtcgacca ctgtgacgac
    18721 cacgatcatc gtgatcgaca cggccagcag cgcgtgacgt ggctcctgag accaacgacg
    18781 atcttcgagg cgtccagaaa ccatatgttc tggatacacc agcggcggtc cgtgtccgtg
    18841 gtggcggcgc cacagcctca cacaggtaca ccccgtcgta cggtcacatg gcgtgcgccg
    18901 cggtgccggg ccgtgtgtag gcctcccggg gagtgagagg tccgtggccg cccgtgcaga
    18961 cgacgaccgt ctccagcggt tcaccgcagt cccggtgccg cacctccaga gggggcccct
    19021 ccgggtccgc cgtataccgg tcgccccact gcttgagggc gagcatcacc ggccacaggt
    19081 cccagccctt gcgggagagc cggtactcgt ggcgggtgcg gtggcccggc tcgcggtacg
    19141 ggacggtgtc caggaccccg gcggcgacca gtttgcgcag ccggtccgac agcaccgcct
    19201 ccgacagacc cacatgccgg cggaagtcgt cgaagcggcg cacgccgttc atggcgtcgc
    19261 gcaacaccag cagcgaccac ttctcaccga tcagatcgag ggtgcgctgc accgtgcagt
    19321 tctcggtgct cgtctccagc caggtcatac cgccatcgta ggctggcttc gccattgaca
    19381 gccaggtctg ggcccggcta acttcgatta ctgaagccag acggggagga aagacgtatg
    19441 acgaggtcac ggacgtacga gtggcaggat ccgagcatct ccgcggccga tgttggccag
    19501 gggagcggcc tcgacttcct gcgcgccgtg ctgagcggac gcctgcccgc gccgcccatc
    19561 gccgcgaccc tgcgattcac cctggagcag gtcgacttcg gccatgccgt cttcgccctg
    19621 gagccggggg aggagcacta caaccccatc ggcagcgtcc acggcggcgt ctacgccacc
    19681 ctcctcgact cggccgccgg ctgcgccgtg cagtccgtgc tgtcggccgg catgggatac
    19741 acctcgctcg atctgaccgt gaagttcctg cgtccgatca ccgtcgacac cggcaaggtc
    19801 cgtgccgtcg gcaccgtcct caatcacggc cgccgcaccg ccctggccca ggccgacctg
    19861 ctcgactccg aggaccgtct gctcgcccac gccaccagca gctgcatgct cttccccgtc
    19921 ccggcgcgct gacccgccgg tccgatccgc cccgcgtagg ctcaacagcg ttgcactgcc
    19981 ggggacttgg aaggcggacc atggggcgcg aggggctgat ccggccgctg ccggagctgt
    20041 tgaaggagca cgccgagcgg gccccgtcgc gggtcgccta ctccgacgcc tcgcgcagtg
    20101 tcacctacgc cgaactggag cgccgcaccc gcgcgctggc cgggcatctc acacggacgg
    20161 gacttcgccg cggcgaccgc gtcgcgatct gcctcggcaa ccgcgtggag acggtggaga
    20221 gttgcctcgc cgtgctgcgg gcgggactgg tcggcgtccc cctcgatccc cggtccgccg
    20281 acgccgagct cgcgcacttc cttcaggaca gcggcgccgc gtacgtcatc accgacgccg
    20341 cgcacctcgc acaactacgg cgcctgggac cgccgtacga cgacatgggc gccctggtca
    20401 ccgatgagcg gttccagcgc gcggccgagg gggacggcac cgccgagatc gacgtactcg
    20461 gactcgacga cccggcctgg atgctgtaca cctccggcac cacccaccgg cccaaaggcg
    20521 tcctgtccac ccagcgggcc gcgctgtggt cgacggccgc ctgctacgcc ccgatactcg
    20581 gcctctcgcc cgacgaccgg ctgctctggc cgcttccgct gttccacagc ttcagccact
    20641 ccctggccat cctcggcgtg accgcggtgg gcgcgaccgc ccggatcgcc ggtgagctgc
    20701 tgccgccggg cggactgcgg caggaactgg acgccgacca cgcggagctc ggcgggccca
    20761 tcaccctgct ggccggtgtg cccgcgacgt atcaccggct ggtcgaatcg tccggcagca
    20821 ccccgccgca agggccgcgg atgtgcctgg tcgccggtgc gccgagcggt cccgcgctgc
    20881 gcacagccgt cgaggagtcc ctcggggcgc cgctgctcga cgcgtacggc agcaccgaga
    20941 cctgcggcat gatcgcgacc aaccgtcccg agggacccag ggtcgacggc tcctgcggac
    21001 cgcccgtgcc cggcgtggac gtacggatcg tcgaaccgcg cggcggcgag gatgtgcggg
    21061 acggcgccga gggcgaggtc tgggtgcgtt cgccggggct gatgaccggg taccacgggc
    21121 agcccgaggc gacggccgcc gcgctgcggg acggctggta ccgcaccggc gacctcggcc
    21181 gccgcgtcga gtacggccat ctgcggctca ccggccgggt cagcgagctg atcatccgcg
    21241 gtggcgagaa catccacccc accgagatcg aacaggtcct gtcccagtgc cccggtgtgt
    21301 ccgacgccgt ggtcgtgggc gtgccgcacg acgtgctcgg cgaggtaccg gtcgcctgcg
    21361 tcgtaccggg cccggacggg atcgacgcac ggcgggtgct cgccgagtgc cgtacccggc
    21421 tggccggtta caaggtgccg gccgagatcc gcgagatcgc cgccgtcccg cgcacggcga
    21481 gcgggaagat cgcccggcat cggctcgtcg tccccgcccc ggtggcggac gcccctgccc
    21541 cggccgctct gcgcgagcgc ctccgctccc tctcccgcga cgaccaggag cgcgcgatac
    21601 gcgagacggt gctcgtcgag acggccgagg tctgcgggca ggcctcgccc gaactccctg
    21661 acccggccag tccgttcgcc gaactcggca tgacgtccgt aggcgtggtc gagctggtgg
    21721 atcgactagg cgcgctgacc ggactgagcc tgccgacgac gctggtcttc gaccacccga
    21781 cccccgccga ggtggcccgc cacctacgcg ctgcactctt cgaggacgag cccggcaggc
    21841 gcccgaaccc gtccggcgga cagggccggg ccgcccacga ggacgatccc gtcgtgatcg
    21901 tcgccatggg ctgccggtac ccgggcgacg tcaactcacc cgaagaccta tgggagttgg
    21961 tggcacaggg ccgggacgcc gtctcggagt tcccgaccga ccgaggctgg gacctggacg
    22021 ccctctacga ccccgatccc gaccgcatcg gcacctcgta cacccggcat ggcggattcc
    22081 tgcaccgggc ggcggagttc gacgccggac tgttcgggat ctcgccgcgc gaggcgctcg
    22141 cgatggaccc gcagcagcgg ctgctactgg agacctcctg ggaggtgtgg gagcgggccg
    22201 gaatcgacca ggcctcgctg cgcgagagcg acaccggagt gttcgtcggc gtgatgtacg
    22261 ccgactacgc ccaccgcttc acccacgtcc acgaactgga ggcgcacctg ggcctcggct
    22321 cggcgggcag cgtggcctcc ggacggatct cgtacgccta cgggctgcgc ggccccgcga
    22381 tcaccgtcga caccgcgtgc tcgtcctcgc tcgtcgcgct gcactgggcg gcgcgggcgc
    22441 tgcgctcggg cgagtgctcg ctggcgctgg ccggcggggt cacggtgatg gcgacgccca
    22501 agccgttcct cgcgttcagc aggcaacgcg gtctggcgcc ggacgggcgc tgcaagtcgt
    22561 tctcggcggc ggccgacggc acggcctggg gcgagggcgt gggcctggtc ctgctggagc
    22621 ggctgtccga cgcgcgacgc aacggccacc cggtcctcgc cgtgctccgc ggctccgccg
    22681 tcaactccga cggtgcgtcc aacggcctca ccgcgcccca cggacccgcc cagcagcggc
    22741 tcatcaccca ggcactggcg gacgcgggac tcggcgccgc cgacgtggac gcggtcgagg
    22801 cgcacggcac gggcacccgg ctcggcgacc ccatcgaggc acaggccctc ctcgccacct
    22861 acggacagga ccgcgagcgg ccactgtggc tcgggtcggt caagtccaac ctcgggcaca
    22921 cccaggcggc ggccggggtc gccggtgtca tcaagatggt gcaggccatg cggcacggtg
    22981 agctaccccg gaccctgcac gccgactctc cgacaccgca cgtcgactgg tcggcgggcc
    23041 gcgtggaact gctgacctcg ccccggccct ggcccgccgc ctcggaccgg ccacgacgtg
    23101 ccggcgtctc cgccttcggg atcggcggga ccaacgccca tgtgatcctg gaggagccgc
    23161 cgggcacgga gagggccgtc tcccaggagc aggccacacc cctccccttg ctgctctccg
    23221 ccgccgacga gaccgccctg cgcgcgcagg cgtcacggct cgcggcccac gcggcgcgac
    23281 ggcccgatct gacacccgcc gacctcgccc actccctcgc ggtgtcgcgg tccgccctca
    23341 cccaccgggc gctggtgccg gcggacgacc gcacacggat gctggacgcg ctcggcgcac
    23401 tcgcgcgggg ccgggacgcg accggagtcg tacgaggact ggcggacccc gggatccgta
    23461 cggccttcct cttcaccggg cagggcgccc aacgcccccg gatgggcgcc gaactgtgcg
    23521 cgaccttccc ggtcttcgcc aaagccttcg acgaggtgtg ccggtatctc gacgaccgtc
    23581 tcccacagcc gctgagtacg gtgctgtccg ccgagccggg ctcaccggaa gcggccctgg
    23641 tggaccgtac ggacttcgcg caggccggac tgttcgcctt cgaggtggcg ctgttccggc
    23701 tgctggagtc gtggggcgtg cgagccgacc gcctggtggg ccattccgtg ggtgagttgg
    23761 cggccgcgca tgtcgccggt gtgctcgatc tatccgatgc ggccacgctc gtcgccgccc
    23821 gtggccgact gatgcggggg cttcccgagg gcggcgccat ggtggcggtg gacgcggccg
    23881 aggatgaagt cgtcgccgcc atcgaggggt tggacggtgt ggccgtcgca gccgtcaacg
    23941 ggccccgctc ggtggtgatc tcgggcgccc gggatgcggt gctcgcggtg gcggccgggt
    24001 tcgaggcgcg cggccgcagg gccgtacggc tgcgggtgag tcacgccttt cactcgcccc
    24061 tgatggaacc gatgctcggc gaattcttgg atgtggcaag ggagttgacc ttccgggagc
    24121 cgcgcatccc gatcatttcg acggtgacgg gccgaccttc cgaactctcc ttgccggagt
    24181 actgggtgcg gcacgcccgg ctccccgtgc gcttcgccga cgcggtacgc cgcctcgtgg
    24241 acgacgggat ctcggcctgc ctggagctcg gccccggacc cgcgctcacc gccgcggcca
    24301 ccgactgtct gaacggatct gtgctcgccg tcgccgcggg cggaggcgcg tacgaaccgg
    24361 agacgctcct gtcggccctg gcacggctgc gggtggccgg cgtcggtgtc gactgggcgg
    24421 cggtgtacgc ggcgcccggc gcccggcgcg tggagctgcc gacgtacgcc ttccaacggc
    24481 agcggtactg gctggacgcg tcgcccgtgg cggccgccga tgccgggccg ctgctgagcc
    24541 cggcgttccc ggtgccggac accgggcgga cggtgctgac ggggctgttg tccgtcgcga
    24601 accggccctg gatcgcggac catgtcgtcg ccgggagggt cgtcgtgccg gcgacggtgt
    24661 tcgtggagat ggccgtgcgg gcgggcgacg aggtgggctg cggcaccgtc gacgaactcg
    24721 tgatgccgac gccgctcgcc ctgcccggtt ccgcgggtgt gcgggtgcag gtcgtggtgg
    24781 gcgcgccgga cgactcgggg acgcggtcgg tcgacatcta ctcccggccg gagggggccg
    24841 aggacaccgt cccctggacc cggaacgcct ccggtcggct gctgcgcgaa catgccgcgc
    24901 acggtgagcc gatgccgtgg ccgccccagg gcgccgagga ggtggatctc accgacgcgt
    24961 acgccgccct cgcggacgcc gggctcggct atgggcccgc gttccagggg gtcggtgccg
    25021 tccggcggcg cggtgacgac gtcttcgccg aggtcaggct gcccgcggcg ctcatctcgg
    25081 aggcggatcg ctacggactc cacccggccc tgttcgacgc cgcgttgcac gcaccactgc
    25141 tggcccggcc cgccgacacg ggcgtggtgc gggtgccctt cgagtggagc ggggtgagcc
    25201 tgtacgcctc gggcgccacg gagttgcggg tcgcggtgac gtcgacgggg acggacacac
    25261 tctcgctgac cctggccgac ctgtccggcc gactcgtggc gcgcgtcgag tcgctgacga
    25321 cgagggaact ccgcgctgac tgggccgagt tgacggtggg tgtggggggc gacctcattc
    25381 gaaaggcact cctgcgcccg gaatggacgg ccctcgaact ccccgccggc gacgcccacg
    25441 cgcccgcctg ggcggtgcgc gggccggacg agctgaacct cgccgggttc ctgccgggcg
    25501 gagtggaccc ggagttcgtc gccgtcacgg cgatcgccgg tgcggacgac tccggtccgc
    25561 tgcccgccgt gcacgagtcg accggcaggg tgctcaagac gctccaggac tggcaggacg
    25621 atccgggcac ggccggcgca cggctggtcg tggtgacgcg ggacgccacc gggccggtgc
    25681 cggacctggc gggcgcggcg gtctggggac tggtccgtgc ggcgcagtcc gagctgccgg
    25741 gccgtgtcgt cctggtggac gtggacgggc ggcccgagtc gctgcggctg ctgccggcgg
    25801 ccgtagcctc cggtgaaccg caactccgat tgcgggacgg gcaggtgacg gtgccgcgcc
    25861 tgacgacggc cgccgacgcc actggcacgc agtcctcctt tgccgcggac ggcacagtac
    25921 tgatcaccgg aggcaccggc gcgctcggcg ctgagctggc ccgtcacctg gtcaccgaac
    25981 acggcgtacg ggatctgctg ctgaccggac gccgcgggga ccgggcaccc ggagccaggg
    26041 aactgcgccg cgatctggag gagttgggtg cccgggtcgg catcgtcgct tgtgacgtgg
    26101 gtgaccgtgc cgcgctggcc gcgttggtcg agggctgcga gccgccgctg accgccgtgg
    26161 tgcacgccgc cggggtcctc gacgacggtg tgctggacgc gatgaccccc gagcggatcg
    26221 cggccgtgct gcggcctaag gccgacgctg cctggcatct gcatgaactg acccggggca
    26281 tgggcctctc ggcgttcgtc gtgttctcgt cggtctccgg tctgctgggc cgggcgggac
    26341 agggcaacta cgccgccgcg aactccttcc tcgacgccct cgcccatcgc cgcgccgccg
    26401 aaggactgcc ggcgctctcg ctggcctggg ggccgtggga gcacggcgac ggcatggccg
    26461 cggaactgcc ccgacagcgg ccacaggcac gtgacttgct cgtgccgctg accaccgggc
    26521 agggcctggc gctgttcgac gccgcgctgc gtgcgacggc accggtcctg gcgccgatcc
    26581 tgctggaccg ggaggcgctg cggtccgacg cggggcagct gccgccgccg ttgcgaggac
    26641 tcgtacgccg gcaccggccg gccgccgcga cgacggcatc gggcccgccg gggcagcctc
    26701 cggagccggg ggcctggcgc aggaggctgg cccccatatc cccgcccgag cgtgaggcgg
    26761 tcctcgtgga gctgctgcgc gccgatgtgg cggcggtgct cggttacccg gacgccggcg
    26821 cgctcccggc cggcaaggcc ctcgccgacc tgggattcga ctccctcacc gccgtgcaga
    26881 tccgcaacgc gctcagtacg gcgctgggtc tccggctccc cgcggccgtg gtgttcgagc
    26941 accgtacggc cgaggatctc gcccgccatc tgctcgcgct cctggaggac gaaccggacg
    27001 acgaaccggg cgacgaaccg gacgccgagc ccgcccccga cgagcggccc gcacacaccc
    27061 tctccgcgct gttccggacg gtcagcgccg gcggacaccc ggtcgcggcc atgcacctgc
    27121 tcgtcaccgc gtccctggca ctgcccacct tcacagccgc ccaaggccgt gcgcacgccc
    27181 tgccgccact gcgccgctcc cacggcgaca gccccggctc cggcaggccg acggtcgtct
    27241 acttccccgc ctaccaccct tcgctggcct cggccgactt cccgtccttc caccgcgcct
    27301 tccaggacga cctggacgtc ctggagttcc cgcaccccgg catcggcgcc ggccccgccg
    27361 tgcccgagga ccgcgccgcg ctggcgcgca cgcatgccga gagcgtgctg cggcaggtcg
    27421 gggacgggcc tttcgtggtc gtaggacgct ccgcgggcgg caatgtcgcg cacctcgtga
    27481 cccatgaact ggagtgcatg ggcagggcac cgtctggcct ggtgctgctg gacacgtacc
    27541 acatcacgcc ggacaacagt gccgaggact ggctgctgtc cctggccgcc ccgcctcgcc
    27601 cggacgccgg acaacccgtc ctcaccgggg acgacgacac cgccctggcc gcgatgggcg
    27661 cctacaaccg gatcttcctc gactggaacc ccgagccggt caccaccccc acgctcctgg
    27721 tgcgcgcact gcgccccaca cccgcgatgg cggcctccgc ggacgcggac gactggcgca
    27781 cgtcctggcc atcggcgcac gacgtcgtgg acgtccccgg cgaccatctg acgatgatgc
    27841 gcgaacacgc ggggacgacc gtgtcggcga tccgcgcctg gatcgacgca cgggcataac
    27901 cggtcccgtc cggccggacc cgcgaaccgg ttcaagacca tcccatcgac ggatcggcag
    27961 aacgattcgg caggtgaacg cggcggcatc cgatcattcg tgacggggcg cgccgcgatc
    28021 ctggtgcgcg tatccaactg atgggcaggc gcgggtcctc ggccccgtcg cctccactgg
    28081 tcaaggagtt ccccttgagt cctcgtcgta tggtgaccgg cgttctcgct tccgtcgctc
    28141 tcgtgctcac gtccctcggc gcggtgaccg cccaggcgat ccccgcggca gccgacccgt
    28201 gcggtttcta cgagaccggc tccgacgcct tctacaacca ctgcacctcg gacggctcgc
    28261 gcgtggtcat caaggtgcgc gtcgcctacg ccgccgacta cgaacggtgc gtcgggcccg
    28321 gcaccacctg gctgggctcc gccggcaaga tccagggcgc ccactacgtc ggccgtacct
    28381 gctgacaacc ggtaaccccc ggggggtcgg gctgcggtcc ccctggggtc ggccgacaat
    28441 gggcagtgga tcgcatgtcc ggcccggcct ggacgccgcg gaggtgtcgg cccgagagga
    28501 acgtgctcat gggcgctgag tcttcgaagg ccgtgcggac gggtgccttc gtcgcggtgg
    28561 cggtcgccct gttctgcatc cagctcgact tcttcgcgct gaacctggcc gtccccggca
    28621 tcgccgacga attcgacgtc accgcttcgg ccgcacagtg gacgctgtcc gcgtacatgc
    28681 tggcgatcgg ttgctgcttc atcgtcggcg gccgggtcgg tgatgtcttc ggtcgccgcg
    28741 gcgtgctgct gggcgggacg gcgctgttcg tggccgggtc cgtgggctgt gcgctcgcgc
    28801 ctgacctgtg ggcgctcgtg ggggcacgga tcgtgcaggg cgtcggggcc gggttcgtct
    28861 tcccggtgtc cgtcgccgtg atcagcaacg ccttccccga cccgacccgg gcgcgtgccc
    28921 tgggagcggt gttcgggatc gccaatgtgg gcaccgcgct gggccccttc gccggcggtg
    28981 gtttcaccga ggggcccggc tggcgctgga tcttctggct tctcgcccca ctgagcctgc
    29041 tgtcattgtg cgtggcttac gggtgcgtgc ccgactcgcg ggatccggac gcgccccgcc
    29101 agctcgatct gatcggctgc ctcaccgtcg tctgtgccct ggcggcgctc accctcgccg
    29161 tggagcgcgg cagcgcctgg ggctgggacc acgcccgcac cctcactctg ctggcggtcg
    29221 ccgctctggc ggggtggctg ttcgtacggc gggagcggcg cgcccggcat ccgctcatcg
    29281 acctccggct cttccgcaac acgccctacg tcctggtcac cggcaccgac gccgcgtacg
    29341 acgcgatcct gcggttcggg ggtgcggtga tcctcgcggc ctccgccgtc gtcatcgccg
    29401 tacgccatcg gctcgtggcc cttggcacgg tcccgccgct cggaccgggt ggcgggcgcc
    29461 tgccgtgaag cccacggcgg agcggagcct gatcctgcac cggtcggtgc gggtgacgct
    29521 cgccgcgtcc gtgggcttct acaccttcgt gtacgggctc gacgaacccg tcctcgcgct
    29581 gtacgccctg ttcgcgccga tctccctcgg cctgctctcc ccgatccccg ggtccggccg
    29641 gcagcgggcc gaggtgatgc tcaaggcact ccccgtgggc ctgctgctgg tcgcgctcgg
    29701 gaccgtcctg gccgtgcgga cctgggcggc ggtcctcggc atgctcgtcg tgggcttctg
    29761 cctcgccttc gcggcgatcg ccggcccgcg ccccgccgcc gcggcacctg gactccagct
    29821 cttctacatc ctcgcctgct tcccgccgta cgaacccgag accctgtggc tacggctggc
    29881 cgggctcacc ttcggcgtgg tgctgctggc gctgtgcgag ctgttcctgc tgccgcagcc
    29941 ggccggcccc acctaccgga cggccctcgc ggacgccctg gtgacggcgg gggacgtcat
    30001 cgccgggcgc accgtcctgt cgcccgaggc gctgcgggag gccggcgcgc ggctgcggct
    30061 gtccgacatc ccgcccgccg aacgccccgc gggcccgggg cgcgcggtgc gtggcctcgc
    30121 ccaggcgggc gccgccgccc gccggctgct cgaacagctg gcccgtctga ccgagaccgg
    30181 cgaactcccc gcgctcgtcc gcgagggagc cgggggcgcc gggggacacc ccgccacggc
    30241 caccggaccg ctgctgccgc aggtgatgtc cctgtgcgac gagaccgccg ccgccctgcg
    30301 caccggccgg gccgctcccg gaccgcagcg gatggaccgg gccatcgacg acttccagcg
    30361 gatgcgggtc cggcaggtga ctggcgccgc cgaccgggtg ccgccggtgc cggtgctgcg
    30421 gcgacaggcg gcactgctgg ccgtcgccga gtcgacgcgc atcctggaga tctccgtccg
    30481 ggtcgccctc gacgggcggc gcaccccgcc gatcgagccc cgggaactct tctggtacac
    30541 ccgggccgcc acgccccggc tgtgggagcg ccgtatcacc ggcaacatga cgctgcgctc
    30601 ggtgcagttc cagaacgccg tacgcatcgc cgtggcgctc gccgtcgcac ggctcgtcgc
    30661 cggatcgctc gacctgacgc acggcttctg ggtgctgctg acggtgctga ccctgagccg
    30721 gaccaccgtc ggggagacct ggggcgccat ccggcaggcc gtcaccggca acctcctggg
    30781 agccgtcgcc gcgggcgccc tgctcatcgg cctcggccgg cacaccgacg gctacgccgc
    30841 gatcctcgca ctggccatgc tgatcgcttt cgccctcggg ccgctgttgg gcatcgcctg
    30901 ggcgcagggc ctgttcaccc tcgtggtggc caccgcgttc gcccagatcg cccccgcctc
    30961 ctggcaactg gccgaggcac ggatcgtgga cgtgatgacc ggcagcgcca tcggcctgct
    31021 gtgcggcctg ctggcctggc ccgccggggc gcgccgagag gtccacagaa ccatggcagg
    31081 cctgctgggg gagtgcggcc cgctgatcaa gggcaccgtc gacctgctga ccgccacgcc
    31141 cccgggctcg gtccccgccc cgcccacgct ccccgccctg caccggctgc gcctcgccga
    31201 gtccgcctac gcccagttcc gcagcgaacc gggcagcggc gcatccgccg gcgccgactg
    31261 gcacgccgta ctcatcacgg cctcccacat cctgctcggc gcgcaatggc tgccccgatt
    31321 cgacctgccc acggccgccg tgcccccgga cgccggggac cgggcacggg ccggcgcccg
    31381 cgcactcgcc gggaccaccg accggctcgc cgccctgtgc cggggacggc gatcgcgtcc
    31441 gcccgcggcg ccgccgccgc tctgggagcc ggccgggccg cccctgccca cgctggtcga
    31501 cctcgacatg tggctgcgcg gcctgagcca ccagctcacc cggatcgagg ccggactgcc
    31561 cgaggcgccg cgcggcacac cgaccgccgg ccgggacgcg ccgtgaccgg ccgggacctc
    31621 cgctccgaac tgcggcctcc ctcgccactg cgcgggtggg tgtggtggct gcccctggtc
    31681 gccgtggtcg tcgacctggc cgccgagttc atcgtcaggg gccgcgaacc ggtgagcttc
    31741 atgctcatcg cggtaccgcc cctggccgcc gcgacacgcg gcccccgcgg caccgccatg
    31801 tccgccgtgg tgtgcctggg gctgcagatg tggatggccg ccagacgccc cggccacttc
    31861 gacgagcagc accatgtcgc cgtctacgtc gccacgaccc tcatcggcat agccagcgtc
    31921 gcgctcgccc ggcaacggga acgcacccgg cagcatctga tccgggccaa ctcggtcgcg
    31981 gaggccatgc agcgaaccct gctgcggccc gtaccgcgca ggctcggccc ggtgcgcgcc
    32041 gccgcgttct acgaggcggg ggagggcggc acgctcgtcg gcggggatct ctacgacgtg
    32101 tgcgagacgc ccttcggcgt acgggcgatc atcggcgacg tccgcggcaa ggggctggac
    32161 gcggtgcaga cggtcgcggc ggtgctgggc agcttccgtg tctcggcgca cgagtgggag
    32221 agcctgagca gcctcgccga gcggctggaa ctgagcatcg cccgcaacag ccccgccggg
    32281 gacgccggtg accccgaact gttcgtgacc gccctggtgc tggagttccc ggcggacggc
    32341 ggcgaggtac gcgtcgtcga ccggggccac cccccaccgc ttgcggtcgg cccggacggc
    32401 gcccggcggc tggccaccgc gcccggactg ccgttgggcc tgggcgcact gacgccggac
    32461 ggtgtcgagg cgaccgtgca tgtgctgcgg ccctcggagg tgctcgtcct gcacaccgac
    32521 ggggtgagcg aggcccggga cacggacgga gtcttctacc cggtccagga acggctcggc
    32581 gaacggttca ccggcgagcg cgcacccgac ccggagacgg tcgtgtcgtt cgtgcggacc
    32641 gactccgaac gctgggcggc gacggagtcc gacagcgacg accgggccgt cctcgcgctc
    32701 accctggccg cccccggacg agggatcacc gcccgcgcgg accgagcctg atgtggcgga
    32761 tgaccttgcg gtggtgggtg taggcgatgt ggagggctcc gtccgggctc tggacgatcg
    32821 aggggtacga cagctcgcgg ttgacgccgt cgcgggagtt gttggtgagg cagtggccgt
    32881 cgccggtgac gaggtcggcg cgcagcggcc aggtgcggcc cgcgtccgag gacagcgcga
    32941 gactgagcgg ggcccggggg gcgccccaga acgcggccga cggggcctgc ttcaccgcgg
    33001 tcgcccccgc ctcctccccg gtggccagag cgccggagtc gtcgatctcg tcgtacaggg
    33061 agacgcggcg ggccgtggcg tcggcggcgc tgctgtggtt gtagacgagg gccaggcggc
    33121 cgtcggccag cgggacgtac tggatcgacg agttgttgtt gggcagggcc agcggctccg
    33181 gatcgctcca ggtgtcaccg tcgtccagcg acacggaacg gtgtacgtgg tcggcgcgcc
    33241 ggctgcggaa gagggcgacc agtgagccgt cgggcagccg gtggacgttc atatggacca
    33301 gccccgtgga gccgggcacg ggctcctcgc gccacgtccc gccctcgtcg tcgctgatca
    33361 tcacggcgct ggtgtcgagg tcgccggacc acttcacccc cggggtgacc acacagcgga
    33421 agacgggcag caggagacgg cccgtgggca gcaccaccgg gggctggcgg acgaagacgc
    33481 cgccgtcgcc gggtgtcgcc gggaacaggg tgcgggtcgc gtcccagctg cccgcgccgt
    33541 catgactgac gcgcagccgc acctcggcgg tgtcctgatc gccgccccgc tgcgcggtgt
    33601 gcagcagcca cagggcgccg gagggcgtcg ggaagagcag ggggttctgc tcggagcggg
    33661 tcgggtcctc cgacagccgg accgggtccg tccagaccat gccgccgggc gccagccgcg
    33721 agaaccacac ggagatgtcg gccatgccct cctgcgtacc accgaaccag acacagccga
    33781 cgtccccgcc gggcagaacc gtgagattgg cggcatggct ctgcacggtc ggcgcgggca
    33841 gggtggtgtc cgtgcgggcg taggcgtcga ggagtgggtg cgtcacggcg tcgctccagg
    33901 ggtccgggcc gaggtcggat ggtggcgggc ggtctgttcc gggtggacca ggtcgcagga
    33961 gacggtggcg taggtgatgc tcttggcgag gcgcttggtg gcgctcgggc cgtccgggtt
    34021 gtggatgccc gaggcggccg ccgcctcgcg gaccctgacg agcgtggcct cgaaggcgtc
    34081 ggccagggcc gggtcgggcc cgatccgcag cgaggagcgc atcgggccgt aggagcgccg
    34141 acagtgcggc gggtagcgga cggcggcgac ggcctcggcg gcctgcgccg acgtgtcgac
    34201 cagcggcaag attgccacgg gcgcgtccaa caggcgccag tgggcgagga gttgctcgcg
    34261 ggcgcgccgg gcggcggtga actctgccgg agtcatggac agtcgttttc tcgcggcggt
    34321 tgtgggcggg cagcggcccg gcgtggatgc gttcgtcgtc cccgcccgcg tgaccgttgg
    34381 ccgtgtccgt gtcggtgccc ccggcctcca tcgccgcggc gcccgcccgg tcgagccgtc
    34441 acacgggcac gggtacgttc ggcggttcga tacctgggtc acttgccggt tccttctggt
    34501 gagacggcgg tcgcggcccg gggcttgagc cctcggatcg ccgccgggtc cagtgcggcg
    34561 cggcgcagtg cgcgggtgta cgggtcggtg ggggaggcga gcacggcggc ggtgcggccg
    34621 cgctcgatga cccgtcctgc cttgagtacg accatgtcgg tgctgatctc ccggaccacg
    34681 ccgagatgat gggcgatgac gatgtaggtg atgccggtct ccgcctgcaa ctcccgtagc
    34741 agatcgagga cttgagcctg cacggacacg tcgagcgcgg acgtcgcctc gtcgcacacc
    34801 agcagatcgg gctccgaggc cagggcccgc gcgataccga tgcgctgccg ctgcccgccg
    34861 gagaactccg ccggccgccg ctcccgtgcc gaggccggca gccccacacg gtccagcaac
    34921 tcggcggcac agcggcgccg ttcggccttg tcccgcaccc cggcgaggcg cagcggctcc
    34981 gccacgatcc gctcggccga cagatggggg tcgagggagc cgtaggggtc ctggaagacc
    35041 atctgcgccc ggcgccgcag cggccgaagc cgccgctcgg acagcgcggc gagatccgtg
    35101 ccgtccagca cgacccgccc ggacaccggc ttcagcagcc gtacgatcgc gcgggccagg
    35161 gtcgacttgc cgcagcccga ctcgccgacg accgccagcg atccgccgcg cggcacatcg
    35221 aaactgacgt ggtcgacggc gcgcacgggg ccggccgggg tgtcgtagtc cacgacgagg
    35281 tcctcgaccg cgaggaacgg gggcggcgct gaaggctggt tcatcgtgcg gctcccaacg
    35341 gcgtgtggtc ggcgagtccg tcctcgtccc agggcccgag ggccgggacc gccgcgagca
    35401 gcgtccgggt gtaggggtgc gtgggccgtt ccacgatccg ctcggcgggc cccgactcca
    35461 cgaaccggcc ctccttcatg acatggatgc ggtcggacac cagacgtgcg acacccagat
    35521 cgtgcgtgat catcagcatg cccacgccgg tgcgttcctg gaggtcgagg aggagatcga
    35581 ggacgccggc ctggacggtg gcgtccaggg cggaggtcgg ttcgtccgcg acgagcagcc
    35641 gtggttccgc ggccagggcg atggcgatca ggatgcgctg gagcatgccg ccggagaact
    35701 ggtgcggata cgtcttccag cgcgtccccg gctcgctgat ccgcacctgg tccagcaacc
    35761 gcgtgccgcg ctcgcgggcc tcggcgcggg acaggcccgg gtggcgcagt cgcagcgcgt
    35821 cgccgagctg ccggccgatg gtgtgcacgg ggctgagcgc ggtcatcggg tcctgcggga
    35881 tcagcgacac ggtacggccg cggacccgcc gggccgcctc ggggtcggcg acgacgtcct
    35941 caccgccgac ccgggcggtg ccggacagta cggccaggcc ctcgggcagc agccgcagga
    36001 cgcccatcgc ggtggtcgac ttgccggacc cggactcgcc gatgagcgtg acggtctcgc
    36061 cctggccgac ggtgaagctc acgccgtcca cggcgcggac caccccgcgg tgggtgacca
    36121 gctcgatctg gagatcctcg acctccagca ggggggaggc gtcctcggcc atggctcaga
    36181 ctcccttcgc cggcttgtgg gtgcggaccc ggtcgcgcag gccgtcgccg agcagattga
    36241 cgccgaccac gagcagggcg atgaccagac cgggcagcgt gaccagccac cacgaggtgg
    36301 tgatgtagtc ctggccgtcg gagatgatgc ggccccacgt ggcgaacggc cgctggggcc
    36361 cggcccccag gaagctgagg gcgctctcca ggagcaccgc ctgggcgagc agcagcagga
    36421 ccaccaggct cgcgggacgc agcacgttgg ggacgatgtg ccgcgccagg acggaccagc
    36481 cgcgcagccc gagcagccgg gccgccgcga cgtacggttt ctcgcgttcg acgaggacga
    36541 gcgagcgggt cagccgggcc acctccggcc actgggcgac ggcgatcaca caggtgatga
    36601 cggtgaccga cgggccgaac agagcgacga cgagcagcag catcatcagc aggggcagcg
    36661 ccagttgggc ctcaaggagc cggctgacga ccgtgtcgat ccagcccccg aagtagccgg
    36721 ccgccgagcc cgccgcgatc ccgatcagac cggagacgac gacggccagg acacccaccg
    36781 tcagcgacac ctggccgccg tgcagcagcc gcgacagcag atcgcggccc agctggtcgg
    36841 tgccgaagag atgtccgtcg gtgagcggcg gcagacggcg ccgggagagg tcctgtgtgt
    36901 tcgggtccgc cagcggcaac aggccggcga gcgccaccgg cagcgcgacg agcgcggtgc
    36961 agaaggcccc ggcccacagc ttgacgcggg cgccacgacg ctgccgggcg gcggaggaac
    37021 gggcgaggtg ccgctcggag acggcgctcg gccgctcggg aggggccagg gtggtggtca
    37081 tggctcaggc cgcctttccg agtcgtaccc gcgggtcgag cagcgggtag gcgagatcga
    37141 cgaggagttg gacgaggatg gcgagggtgg ctgtgaccag gacggtggcc tggatcagcg
    37201 gatagtcgcg ggtctccagg gcacggacca cgagcgagcc gacgccgggc cagccgaaga
    37261 cgacctcgac cacgaccact ccgttgagca gcgccgcgaa gcgtgtgccg accgcggtga
    37321 ccagcgggac cgccgagttg gccagcgcgt aacgccaggt gagggcacgc tcggagacac
    37381 cgcgcgagcg ggccacggtg atgtacggcg aggcgagtgc cgtggtcatc tcacgccgta
    37441 ccagccgtga gaccagggcg agttggagga tcgccacggt gaccgtcggc aggatcagac
    37501 cgctccagga cgtgaagccg gacgcgggca gtaccggcag cagcacggcg aacaccgtca
    37561 gcagcatcac cccggtccag aagtccggca tcgactgtcc cgcgatggtc aggacgttgg
    37621 caccgagctc gcgcttggtg tccgcgcgcc gtgccatcca cacccccagc gggacggcga
    37681 cggccaccgt gacggcgatc gccgcgaccg acagcgtgat cgtgtacggc atgcgctcca
    37741 ggaccacgtc cagcgccgag gaatggaagg agtagctggt gccgagatca ccggtgagca
    37801 ggtcgcgcag gaagatcccg tactgggtga tcagcggttc gcccagcccg aactcctcgc
    37861 ggatccgcgc cagatcggca ctggtcgcgg tcgggcccgc gtacgcggcg gcggggtcgc
    37921 cgggcgcgag ccggaccagc acgaacacgg tggagacggt caggaagacc gtgagcaggc
    37981 tctggcccag acggcgggcg aggtatctcg acacggctca gccctccagc cgtacggcgg
    38041 tcaggtcgta ggagttgacc ggcagcagcc cgatgccctc gacgcgggtg cggcgggcca
    38101 gcagggtctt cggcacgaac gcccacagac agggccatgt gtcccatacg gcgtgctggg
    38161 cggcggcgag ttcgcggtcc cgggcggcgg ggtcggcctc ggtggcggcg tcggagatcc
    38221 gccgggcgat cgcggggtcg acgtagccca tgaaggcgtc gccggtgcgc tcgtcctcgg
    38281 cggtccccgc gtacatggcc tggagcatgg tgacggcctg gccggtgggg ccggggaagc
    38341 cgttgccgat gacgtcccag tcgccgccct tgccctgacg ccacttgagg atgtcgccgc
    38401 cgggctcgaa ctggagcagg gaggtgcgca ccccgacgtc cttcagcatc tcggcgaccg
    38461 cctccatgac ggaggtgtcc gcggcgaact cccccgactc ccacatgatc ctgatccgca
    38521 gcccgtccgc gcccagcgac ttcagcgact gccgtgcgcg ggccggatca tggacgaagc
    38581 ttccggtgcg ttcggcgccc tggagggaga gcggtacgac gcccgcggcc tgctccgccg
    38641 agccggtgag gacgtcccgc acgagggact cgccgtcgat ggcgtacgtc agcgcccgcc
    38701 gcacccgggc atcggcgagc gggtggtccc tcggcttgcg gaagttgtag aagagctggc
    38761 acagccgtac cccggaggtc tgctccagat gtacgcccgg cagcccggtg agctgttcgg
    38821 ccgagtccgg tgtgatggtg tcgatgacgt cgagttcgcc gctgcgcagg gcgacgaccc
    38881 ggctcgactc ctccggcacg aagcggaccc ggacccgctc gacggccggc cgcccgcccc
    38941 agtagcgggg cacccgggcc agggtgtact caccggcccc gctgttggcg ccgaccacgc
    39001 ggtacgggcc ggtgccgaca ccggagcgca gttcctcggg ccggttgtcc ttcgccgggg
    39061 tgatgaggat gttggccatc agccggtcca gtacgggcac cggctgccgg gtgtggagca
    39121 ggaaggtacg ggcaccggtc gcctcgacgc tcggcagctc ggggaagagt ccgagcacga
    39181 acgacccggc gacctcgccg tacatccgca ccgcggtggc cacgtcctcg acggtcacgg
    39241 ggcggccgtc ggaatagcgg atcccctcgc gcagccgcac gctccaggtg gtcggcgcgg
    39301 tcatctcgaa ccggtcggcg aggaccggcg tcggcttcat gcccggcccg atcgccgtga
    39361 gcgcctggcg cacggcccgc tgcacggtca ccgccgcgtc gaactggttc agcttgttgt
    39421 ccaggctgac cagcgaacgg ttcaacccga gcgtgagcgt gccggggccc ggggcgccgg
    39481 tgggcccggc gcaggcggcc agcggggcga ggccgagacc ggcgccgccg gcggcgcccc
    39541 agcgcagcag ggtgcggcgg gtcaacgtct cgtgcggggg agtcggggtc gtcctcgggg
    39601 gagttcgggt catcgtcgac ctctcgggat tctggtgcgg cgaccggctc ggggcggtgt
    39661 ccggtcccgt gggacaccac cggtttctgt cgcggcgaaa accgttccac ggttgcgcac
    39721 atcgcgcaag aggtctcgcg cacatcgcgc aggatgtgtc atcatcgacg cgccgaggcc
    39781 gtctctggac tcccttgcgg agaggggtga gggacacagc cccgacgagg gccggaccac
    39841 ggcggatcag acgacggacg gcagcggatc agacctcgga ccagacagga tcggaccacc
    39901 gaccaccagg aggcgggcat gtccttcact tcccgcgacg cgccgacgcg gcctgccgac
    39961 gccggcgcgc gggtgacgcc gccccacccc gacgcacgga tccggccatc cgccgccgac
    40021 acccggacgc ctcgccccgt gctcgcgctc gccgacgacc tgtccggcgc cgcggagacc
    40081 gccatggccc tcggcctgcc gggcagaatc gtgctcggcc ccgcgcccag cgccccgcca
    40141 ggcgaaggcg acgccgtcgt ggtcgacctc gactgccggg gcgtcccccc ggatgaggcc
    40201 gcccggcggg tccgcgaggc cctgcgcacc gtccccgacg gcgccctggt gctgaagaag
    40261 gccgactcgc tgctgcgggg caacctcgcc gccgagacgg ccgccttcac ggacggggcc
    40321 gagggtgtcg tcgtcaccgt cgccctgccc gcactcggcc ggacggtccg cgagggcgtg
    40381 gtccatctga gcggcgtccc cctgcaccgc acggacgcct ggcgcgcgga ggtcaccggg
    40441 cccccgacgt cggtggcagc cgcgctcggc gacagccgta cggccgtcgt cccgctggcg
    40501 gcggtccggg acggcgcgtt gccccgcgta ctccgggaca cgatcgccgc cggacgcctt
    40561 ccgctctgcg acgccgagac ggacgccgac ctggaccgca tcgccgacgc ggccatcgcc
    40621 gcgggccccg gtgtccgcct gctcggcacc gggggcctcg cggctgcggt ggggcgcctg
    40681 ctcggccgta ccggaggggc ctcggcgccg gccgggacgc cggtgcggcg ggagcgacgg
    40741 ccgctgctga tcgtcgtagg caccgccgaa ccggccgcgg ctgcgcagat cgcgcaactc
    40801 gcacagcgcg gcgcgcgcca catcgccctg cccgccgacc ggctgtcgac gacggacggg
    40861 cacgccgccg gcacctccga cgtcaccgtc ctcagcatcg acaacggcca acgcgtccaa
    40921 cccggttcgg cctaccgccc ggtccacgga ctcgcgcgtc tcgccgccca ccacgcggcc
    40981 ggcgccgacc tcgtcctcac cggcggggag accgcgcgac gcgtcctcga cgccctcgaa
    41041 gtcccgcagt tgacgccgct cggcgagatc caccacggcg ccgtccacgc cctcgcatcc
    41101 gacggacgtc atgtcgtcac ccggcccggc agcttcggcg agaccgactc gctgctgcgg
    41161 atcgccgccg ccctgcgccc ggaccggttc cgcaccccac cgctccacat cccgacgccc
    41221 gacctcccac cgcaaggaga ccccctggtg aacgccactc cgaccaccgg cgaccgccgc
    41281 ccgctgccgc tcatcgcggt gaccatggga gacggcgcgg gcatcggccc cgaggtgatc
    41341 gtcccggcgc tgctgcaccc ggacaccctc gcccgctgcc gccccgtcgt cgtcggcgac
    41401 gccgaacggc tgcggcgggc cgccgcgatc ctcggcgtcg actgcgacat cgtcgccgtg
    41461 gccgccccgg aggaagccga gttccggccc ggccgcgtca acgtcgtcga cctcggtctg
    41521 atccccgccg acctgccctg gggcgagttg tccccggtcg cgggcgacgc cgcctaccag
    41581 tacgtgcggg tggccgccga cctcgcgatg aagaacgccg tgcacggcat ctgcaccgcc
    41641 ccgctcaaca aggaggccct gcacgcggcc gggcacctct acccgggcca caccgaactc
    41701 ctggcccacc tcacgggagt ggacgaggtg tcgatgatgc tgtcgacgcc caaggtcaag
    41761 gtcatccacg tcaccaccca catcggcctg atcgacgccg tgcgccgtat cgagccgggc
    41821 ctcgtcgaac gcaccgtgcg acgcggccac gaggcgatgg tgcgcgcggg cgtggcgcag
    41881 ccggtgatcg gcgtgtgcgg catcaacccg cacgccggtg agaacggcct gttcggctac
    41941 ggcgaggagg aggagaagat cgtccccgcc ctggagatac tccgcgcgga cggcatcgac
    42001 gcccgcggcc cgctccccgc cgacaccgcc ttcttcctcg ccgggcgcgg tgactacgac
    42061 ctgatcgtcg cgatgtacca cgaccaaggg cacggcccgg tgaaggtgct gggcatcgag
    42121 gccggtgtga acctgaccgt gggactgccc gtcatccgta cctccgtcga ccacggcacg
    42181 gccttcgaca tcgcgggcaa gggaatcgcc gacgccggta gcatggtcga ggccctgcgc
    42241 caggcagccg agatgtcctc cgtaccggcc ccctgacccc tccgctgacc ggccccctga
    42301 aaccgccgcc cagcagccca cgcagcgaag gactccacga cagatgtctc ccaccggatc
    42361 ccaggcccgg cgcgaccgga tcctgcacct ggccaccacg accggcctga ccagcgtcga
    42421 ggagctgtcc cagcgcttcg gcgtcaccgc ctccaccatc cgccgcgacc tcgccaagct
    42481 gaccgccgac gggcgcctcg cccgcaccta cggcggcgcc atggcgctga ccgcccaccc
    42541 cgaggcgtcg cttcggcagc gcaccggcga ggcgttcgag gcgaagcggg ccatcgcgcg
    42601 ccgggccgcc gccgaggtgg gcgcgggcga gacggtgctg ctggacgccg gctcgacggt
    42661 gggcgccctc gcccacgaac tgcgctcggc gaaggaactg accgtcgcca ccaccggact
    42721 gacggccctt caggaactcg ccgacgtcga gacggtgcac gtcgaatgcc tcggcggcac
    42781 cctgcgcccg ctcagccagg gcttcgtcgg accgctcacc gaggccgcgc tggaacacat
    42841 gaccttcgac cgagtcttcc tcggcaccga cggcatctcg cccgagcacg gcatctgcga
    42901 ggccgacctg cgccagaccc ggctgaagga actgatggcc cgccgcgccg accacgtcta
    42961 cgtcctcgca cacgcggcca agctcggccg gcgccccttc cacgcctggg cgaccctccc
    43021 cgagggctgg accctgatca ccgacccgga cgccgacccg gcgaccctgg acgcactgag
    43081 cgagcgcggc gtcgaggtgg tcctggcgga ggtgcccccg ccggccgccg actaccccgc
    43141 cccgccgacc ggttcgggcg caccggatgc ctgaaccacg ccacgccctg gtcaccggcg
    43201 tcagctccgg aatcggcgag gccatctgcc ggcgcctgct ccaggacggc tggcgggtca
    43261 ccggcatcag ccgccgccga ccggtgcccg cgcccggcct gacctggctc cgggcggacc
    43321 tggccgaacc cgccaccctg aaccggaccc tcgacggcat cgccgccccc gacgcgatcg
    43381 tgcacgccgc gggactccaa cgctccgctc cactgggcga gttgtccgcc gacgacggcg
    43441 aactgatgtg gcgcgtccat gtccagtccg ccgtgatcct cctcgacagg ctcgccgccc
    43501 gactgcccga cggcgcccgc gtggtcctcg tcggcagccg tacggcgacc ggtgtgcccg
    43561 gcaagagcca gtacgccgcg accaaggccg cgctgcccgc gctcgcgcgt tcctgggccg
    43621 ccgaactcgc gggccgcggc atcaccgtca atgtggtcgc ccccggtccc accgacaccc
    43681 cgatgctgtc cgaccccggc cgcgcccgca ctcccgtggc gcagcccccg ctcggcaggc
    43741 tcgtcacacc cgacgaggtc gccggcctca ccgcgttcct cctcgggccg gagggcggcg
    43801 cgatcacggg ccagcaactg gtgcagtgcg caggggcctc gctgagtcgt tgagcgggga
    43861 cgccgtcgag cgtggtgcct tcacgcgtgc gtgccgtcag ccggcccggt tcgggatgcg
    43921 gagccgcacc tcgtagccgc cgtcaccggt gggccctgag gcgaaggtgc cgtccaggag
    43981 ctcggcgcgt tccttgaggc cgatcaggcc ctgccgggaa ccggggaggg ggagcgacgg
    44041 ccgggcgggc ggtgtgttcg tgacggtcac accgaaggcg tcgccgtcgt gccagaggtg
    44101 tgcggtggcg gtggcgccgg gcgcgtgctt gcggacgttg gtgagggctt cctggacggt
    44161 gcggtagatg gttcgctgcg cggtggagct gacgtcaggg gggagttcgc cggtgagttc
    44221 ggcgtcgatg ccgctggtcg tgacgagctt gtgcagatcg gccagcgtgg gctgcggcgt
    44281 gagctcggtg gaccggccac cggaggcgcg cagcagggtg accatgtgcc gcagttcgtc
    44341 gagcgtgtcg acgctgagcg agcggatggt gcgggcgccc tccctgaagt ccgggtcctt
    44401 cgcggcgact tggagtgcgc ctgcctgaac ggcgatcagg ctgacctggt gggagacgac
    44461 gtcgtgcatc tcgcgggcga gctgggcgcg ttcgcgggcg aggacagcct gggagtgcag
    44521 cagacgctcg tgctcacgtg cctcctcgat ctcgacgagc cggcgggcca ggtcccggcg
    44581 ggcctggacg agttggccca gcagcacggg ggccgcggcg gtggcgagcg tgtagaagaa
    44641 gtagaccagc gtccaggcgc gctcgtgcga ggacaggtcg tccagcggcc agggagtggc
    44701 cgaggcgacg gcgaacagca acgcgcaggt gaccagcagc cggcggtcac gggagcgttc
    44761 ggacagcgtg aacagggccg cgaacggggc gaacacgatg tccagcatca ggctggcggg
    44821 gagcgtgagc aggaacaccg ggagcgggaa ccgccgccgc acgatcagcg ccgcgcacgc
    44881 cagcgtcgcc atggcccaag cggggccgct cgtgtcgtcc aggttgatga ggacgtccac
    44941 cacggcgacc acgacgacca ccgcatcgag gaccggctcc gggatcctcg cccaccacgc
    45001 tccgcgcgcg ccgctcatcg cccggacccc gggcccgcct cgccgtcccg ctgcccttcg
    45061 tccagcagcc cggcccgctg cgccagcagc gccgcctgca ccctgccgcc gacccgcagc
    45121 ttggtcagga tcgcgctgac atggtccttg accgtgcccg cgctgagatg gatacgggcg
    45181 ccgatgtcgg cgttggacag cccttcggcg atcagcacga gcacctcacg ctcgcgctcg
    45241 gtgagcctgc cgacgcgggt gctgtcctcg tcgtccacga ccgccgcgcc ggggtggttc
    45301 tgccacacgg cgcgcgacgc cttcggcgac atcacgacgc cgcccgcgac cagggtgcgc
    45361 acgagctgcg cgagctggtc gggctcggtg tccttgagca ggaacccggc cgcgccggag
    45421 cgcagcgcgg tgaggatgta ctcgtcggcg tcgaacgtcg tcagcatcgc caccaccggc
    45481 ggttccggta gcgcccgcag ccgccccagc accgtcagcc cgtccacgtc cggcatccgg
    45541 atgtccagca gcacgacgtc ggggcgttcc cgccgtacgg tgtcgaccgc ctcggcgccc
    45601 accgaggtcg cgacgacctc gatgtcatcg gccgcgctca ggatcagatc gaatccggag
    45661 cgcaccagcg cctcgtcgtc caccaccatg acccggatca cgtgcgctcc gcctcgtcgt
    45721 cgttgtgcgt acgtctcagg gcgcacgtct atgttgattg tcaccgcttc gacggtatgt
    45781 cgagaaccgc ctggtgagac cgcacgacgg gacactcccg ccacccgggg ggtgggttcc
    45841 caccgtacgg gggaggcacg gcgcccgggc cacggggtgc ttgcggcagg acgagggatg
    45901 gtgccgccga ggccgcacga gctgtcctgg acagacgacg cccccgcccc ccacggcccc
    45961 cgcccggcac cccccacccg ccacccggcg gggtatgacc ggacactcgc cggatacccc
    46021 gcgccccggc ccctcgccag cttggaggta tgacccagaa cgcagaggac acggtgctcg
    46081 cggtgcgggc ccccacccgc cccgagatgg ccacgaggac gcccgccggg gttccggaga
    46141 gtgggcgggc ctcggtcggg cggttggtcg gtgtggatct ggcccggggg ctcgcggtgt
    46201 tcggtatgtt cgcggcccac gtcggtcccg acccgtcgca gggcggtatc accgggaact
    46261 tgatggagct ggcgcacggc cgtgcctccg cgctgttcgc gttcctcgcc ggcttctcga
    46321 tcatgctgat caccggccgt cgtacgccga ggaccggcag ggcgggccgt gaggcggtcg
    46381 ccaaggtggt gatccgtgcc ctcgtcctgc tggcgctggg caccgcgctg acgatgaccg
    46441 gcaccccggt cgaggtgatc ctcgccttct acggcctgta cttcctgctg gtcctgccgc
    46501 tgtaccggct caccgccggc ccgctggcgg tcatcgccgc cggcacctcc ctcgtactgc
    46561 cgcaggtcct gtacgtcgtc aagcaggcgc tccccgccga gggcgtcgac ggcgtctggg
    46621 cctggcccgc ggacgccgac ggcatcgtct cgctgctgtt caccggcagt tacccggccc
    46681 tgacctggat ccccttcgtc atcgccggca tggccgtggc ccgcctcgac ctggccgcca
    46741 ccgccgtacg catacgcctc gccgtcaccg gcgtcctgct cgccgccctc ggctacggcg
    46801 gctcgtggct ggccctgcat ctggtcccgg gagcgatgac cgagctgggc gccgtcagtt
    46861 ggggcggcgc gggttcggtg tcgtccgcct ggtggtccga cacctggggc ttcccctacg
    46921 acagcaccac ggccgggctc ctggtcgcct cgccgcacag cgagacgacc ctgtcgatac
    46981 tggccaacac cggtgtggcg ctagcggtcc tgacggcctg tctcgccgcc gtcgacgcct
    47041 ggccccgctt ccaccgcctc gcccgccccg tgatcgcggt cggctcgatg tccctgaccg
    47101 cgtacgtcct gcacatcgtc ggcatccgtc tcctcggcat cgaggaactg cccggcgccg
    47161 ccctccatgt gctgctcggc ttcatcgtcg cgatcaccgt gttcgccgcc ctgtggtcat
    47221 gccgtttccg ccgtggcccc ctggagtggc tgctcggcaa ggccaccaag cccgccgaac
    47281 tggtccggtg acccgagtgc ccggcggccg ccggggcgta aggcccgcgg cgaccaccgg
    47341 gcacccgtgt ctcagccgcc cagcacgggc aggaccagcc cgcatcggac gggccgcgcg
    47401 tgcgcgggat cgagggcgtt gcccaccagt tgcgcggcgt tggtgtcgta cgcgagcgac
    47461 agatgctcgg agatgtcctg cgggcagatc cgctggatca ggatgttgcg gacggtcgcg
    47521 cccggtccgg cggtcaggaa gttgttccgg tagggggtgg cgaactcgtc gtacttggtg
    47581 gcgatgacgg tgtagcggac gcccggctgt gtgtccccgt cccggtcgag cttcttgttc
    47641 atctcggagc cgaccatctg gtccgaccat gcctggccca cgacggcgga cacggccggg
    47701 ttgaggccca gctgggtggt cagcgtgccg atgccggcga cgttcccccc gtggttggac
    47761 ggggccaggg cgacaaggct gcgtaccttg ttccgcttcg ggtgcgccgg gttcgtgccg
    47821 ccctcgaacc gcagatacca gcggggtgtc ggaccgccgc cctgggagtg cccgacgatg
    47881 tcgacctggc gggcaccgg
//