LOCUS       NZ_BNBM01000004        32567 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces lanatus strain JCM 4588 sequence04, whole genome
            shotgun sequence.
ACCESSION   NZ_BNBM01000004
VERSION     NZ_BNBM01000004.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces lanatus
  ORGANISM  Streptomyces lanatus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 659677)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 61X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014655715.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 05:46:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,254
            CDSs (total)                      :: 9,172
            Genes (coding)                    :: 8,973
            CDSs (with protein)               :: 8,973
            Genes (RNA)                       :: 82
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 199
            CDSs (without protein)            :: 199
            Pseudo Genes (ambiguous residues) :: 0 of 199
            Pseudo Genes (frameshifted)       :: 83 of 199
            Pseudo Genes (incomplete)         :: 153 of 199
            Pseudo Genes (internal stop)      :: 16 of 199
            Pseudo Genes (multiple problems)  :: 50 of 199
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:57:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 402169
            Orig. end                         :: 434736
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BNBM01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..32567
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /region_number="5"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..32567
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..32567
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:18567](+)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14001..18567
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     gene            complement(467..1552)
                     /locus_tag="IE325_RS13780"
                     /old_locus_tag="GCM10018780_27830"
     CDS             complement(467..1552)
                     /EC_number="1.1.1.306"
                     /GO_function="GO:0050607 - mycothiol-dependent formaldehyde
                     dehydrogenase activity [Evidence IEA]"
                     /GO_process="GO:0010127 - mycothiol-dependent
                     detoxification [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (23-256). E-value: 5.6e-13.
                     Score: 40.6. Matches aSDomain:
                     nrpspksdomains_IE325_RS13780_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959558.1"
                     /locus_tag="IE325_RS13780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_27830"
                     /product="S-(hydroxymethyl)mycothiol dehydrogenase"
                     /protein_id="WP_190070123.1"
                     /sec_met_domain="ADH_N (E-value: 2.9e-27, bitscore: 89.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 3.9e-33, bitscore:
                     109.4, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQEVRGVIAPGKDEAVRVETIVVPDPGPGEAVVQVQACGVCHTD
                     LHYKQGGISDDFPFLLGHEAAGVVESVGEGVTDVEPGDFVILNWRAVCGSCRACLRGRP
                     WYCFNTHNAKQKMTLTDGTELSPALGIGAFAEKTLVAAGQCTKVDPSVSAAVAGLLGCG
                     VMAGIGAAINTGNVGRGDSVAVIGCGGVGDAAIAGANLAGAAKIIAVDIDDRKLEKARS
                     MGATHTVNSKETDPVEAIRELTGGHGADVVIEAVGRPETYKQAFYARDLAGTVVLVGVP
                     TPEMKLELPLLDVFGRGGALKSSWYGDCLPSRDFPMLIDLHQQGRLDLGAFVTETIELT
                     DVEKAFERMHHGDVLRSVVML"
     CDS_motif       complement(716..748)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS13780_0002"
                     /evalue="1.00E+00"
                     /label="PKSI-ER_m2"
                     /locus_tag="IE325_RS13780"
                     /protein_end="279"
                     /protein_start="268"
                     /score="3.0"
                     /tool="antismash"
                     /translation="RDLAGTVVLVG"
     aSDomain        complement(785..1483)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS13780_PKS_ER.1"
                     /evalue="5.60E-13"
                     /label="IE325_RS13780_PKS_ER.1"
                     /locus_tag="IE325_RS13780"
                     /protein_end="256"
                     /protein_start="23"
                     /score="40.6"
                     /tool="antismash"
                     /translation="VPDPGPGEAVVQVQACGVCHTDLHYKQGGISDDFPFLLGHEAAGV
                     VESVGEGVTDVEPGDFVILNWRAVCGSCRACLRGRPWYCFNTHNAKQKMTLTDGTELSP
                     ALGIGAFAEKTLVAAGQCTKVDPSVSAAVAGLLGCGVMAGIGAAINTGNVGRGDSVAVI
                     GCGGVGDAAIAGANLAGAAKIIAVDIDDRKLEKARSMGATHTVNSKETDPVEAIRELTG
                     GHGADVVIEAV"
     CDS_motif       complement(1334..1372)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS13780_0001"
                     /evalue="3.00E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="IE325_RS13780"
                     /protein_end="73"
                     /protein_start="60"
                     /score="10.6"
                     /tool="antismash"
                     /translation="LGHEAAGVVESVG"
     misc_feature    1700..1715
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.24"
                     /tool="antismash"
     misc_feature    complement(1700..1716)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 22.72"
                     /tool="antismash"
     gene            1801..3498
                     /locus_tag="IE325_RS13785"
                     /old_locus_tag="GCM10018780_27840"
     CDS             1801..3498
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170: metallo-beta-lactamase family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742130.1"
                     /locus_tag="IE325_RS13785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_27840"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_190070124.1"
                     /transl_table=11
                     /translation="MYFVDTIDVSGLGNRGYLAGGAHSAVVVDPPRDIDRVITAAARRG
                     VRITHVVETHIHNDYVTGGLELARLTGAAYLVPAAARVAYERVPVADGDRTRIEDNLVL
                     RALATPGHTPHHTSYVLEEAGHAVAVFTGGSLLIGTVGRPDLVEPGLTGRLARAQYESA
                     RRLAAELPDETAVLPTHGFGSFCSATRADGGAETTIGRERQVNAALVKDVETFVAELLA
                     GLDDVPAYYAHMGPANTQGPASVDLTPPRPADAEEIAARLAAGEWVVDLRHRVAFAEGH
                     VSGAVNFEAEGQLATYLAWLLPWGKPVTLLAETPAQLADAQRELVRVGIDRPAAVATGS
                     VADWVRPGERPRSFPRGTFADLAARKDVVTLDVRRDSERQADHIKGSVHIPLHQLRDRL
                     SEIPDGTVWVHCAGGMRAAIAASLLDAAGRDVVAVDDSFDAARTAGLPMARVTPAEAQE
                     RAGSGAVLVDVREALEWAEGHAPGAVLAPLSALTAGASLPDSAQARPVVAICRSGKRSR
                     EAAALLSARGVEVVDVIGGMGAWTEAGLPVVAEPESRVAAESGAPGAE"
     gene            3649..4398
                     /locus_tag="IE325_RS13790"
                     /old_locus_tag="GCM10018780_27850"
     CDS             3649..4398
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016827797.1"
                     /locus_tag="IE325_RS13790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_27850"
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_190070125.1"
                     /transl_table=11
                     /translation="MTALLLGLMAGGVTGLALGALGGGGSVLAVPALIYLLGFTPAAAA
                     TASLVVVALTSATALAAHARAGTVRWRGGAVFAAAGLVPAAVGGVVSGWLSDRLLTGAF
                     AVIAAVAALRMLRPSASVRHEEVPVRPWQVARAGAGLGAVTGVLGVGGGFLAVPALVSV
                     VGLRMRAAVGTSLLVITVNSLAALAARAGSDARIDWLAVAPFAAAAVLGAWDGKRLATK
                     VSGDRLRQIFAWALLAVALFMLADAMT"
     gene            complement(4439..4726)
                     /locus_tag="IE325_RS13795"
                     /old_locus_tag="GCM10018780_27860"
     CDS             complement(4439..4726)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965298.1"
                     /locus_tag="IE325_RS13795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_27860"
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="WP_190070126.1"
                     /transl_table=11
                     /translation="MELQFEGDDLKSVLNRLRRAQGQISGVIKMIEEGRDCEDVVTQLA
                     AASRALDRAGFAIIATGLQQCIADPERGRDNGETSEQMKARLEKLFLSLA"
     gene            4791..5390
                     /locus_tag="IE325_RS13800"
                     /old_locus_tag="GCM10018780_27870"
     CDS             4791..5390
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (165-196). E-value:
                     0.00073. Score: 12.3. Matches aSDomain:
                     nrpspksdomains_IE325_RS13800_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163: rhodanese domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662265.1"
                     /locus_tag="IE325_RS13800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_27870"
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="WP_190070127.1"
                     /transl_table=11
                     /translation="MSSPLAPRALDIDGARTRLPALTVIDVRTPGEYAAGHLPGALNIP
                     LDRLGRALPTLAERPGGELLIVCASGARSENACKLLTEHGIPAMTLTGGTQGWAERGHE
                     LHRPASAPRSTWSMERQVRFTAGSIVLVGLGLGLLHPAWQLLSAGIAGGLVFSALTNTC
                     GMAAILSKLPHNRPRPADLDATLAALAERAQGAQGA"
     aSDomain        5286..5378
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS13800_PKS_Docking_Cterm.
                     1"
                     /evalue="7.30E-04"
                     /label="IE325_RS13800_PKS_Docking_Cterm.1"
                     /locus_tag="IE325_RS13800"
                     /protein_end="196"
                     /protein_start="165"
                     /score="12.3"
                     /tool="antismash"
                     /translation="AAILSKLPHNRPRPADLDATLAALAERAQGA"
     gene            5852..7606
                     /locus_tag="IE325_RS13805"
                     /old_locus_tag="GCM10018780_27890"
     CDS             5852..7606
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998765.1"
                     /locus_tag="IE325_RS13805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_27890"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_190070128.1"
                     /transl_table=11
                     /translation="MSIAETPATPSTWRLLLGYVRPHRWTLLAGAVLSLVTGATGLLLP
                     LVARELIDDLSHDRAITGALLIMSALVVANAALGALGSYVLRRTAESVVLGARRALSSY
                     LLRLRITAVDRSEPGDLMARITSDTTLLREVTTDSLVGLGTGGLTLVATVVMMGLVDPV
                     LLAVTLAVILCAGTVLGVIVPHINKASRQAQDAVGVMGASLERILGALRTVKASGAEHR
                     EERTLHEAAEESWRQSVRAAKWSAAAGNTAGLAMQIAFITVLAVGGARVATGAIDIGTL
                     VAFLLYVFYLMSPIQQVVGAITQYQTGSAALARIQEALRLPSEPAAQPAPLPTTGAEPA
                     ALAFEDVRFRYTEELPYVHHGVTFAVPAQGMTAFVGPSGAGKTTVFSLIERFYDPESGV
                     ITLDGRDLADWELPQLRSAIGYVEQDAPVLSGSLRANLLLGNPDADEEAVTRVLKTTRL
                     DGLVARLPEGLETLVGHRGTKLSGGERQRVAIARALLRRPRLLLLDEATSQLDAVNEAA
                     LRDTVADVARTTTVLVVAHRLSTVTMADRIVVMDAGRVRAVGTHRELVAGDPLYAELAA
                     TQFLATAG"
     gene            complement(7621..8454)
                     /locus_tag="IE325_RS13810"
                     /old_locus_tag="GCM10018780_27900"
     CDS             complement(7621..8454)
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006351055.1"
                     /locus_tag="IE325_RS13810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_27900"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_190070129.1"
                     /transl_table=11
                     /translation="MPVPSTSPPVGAVAHTLGDVYGRLTDLCGVLSVRVAEDAQTGVSA
                     AELVKDESVLDAFVSAEAARIHDRYGVFPRRDVAASRALHDYAWSVSLLMSGAWYLEQR
                     VPRILPEDLRLDLTTAEFTITPGSDLACLPDDPAARLPGVLTVPHEQALEAELRAAVAD
                     HMAPLLDAIGPTARRRSRALWGMVSDDLVSGIWYLGRMLDREDDAVRAASRLLPTAVSP
                     YPSGADFRHLTTDDGRQHPTRTRAGCCMYYTIRPDEACATCPRTCDTERLRRLQA"
     misc_feature    8489..8507
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 28.45"
                     /tool="antismash"
     misc_feature    complement(8505..8518)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.78"
                     /tool="antismash"
     misc_feature    8588..8601
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.15"
                     /tool="antismash"
     misc_feature    complement(8598..8616)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 29.9"
                     /tool="antismash"
     gene            8661..9653
                     /locus_tag="IE325_RS13815"
                     /old_locus_tag="GCM10018780_27910"
     CDS             8661..9653
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995628.1"
                     /locus_tag="IE325_RS13815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_27910"
                     /product="iron ABC transporter permease"
                     /protein_id="WP_190070350.1"
                     /transl_table=11
                     /translation="MPFRALRHVPLFLTGLAALVLCAALSLALGARSVPLGTVADALFG
                     NAHGREALVVTGLRLPRTVIGLAVGAALGVAGAVAQGITRNPLASPTTLGINAGAGFAV
                     VVAIFALKLNSPAQYVWFAFAGAAGAALFAQALARRAGDIDAVRLALGGTVLQLVLLSW
                     TSAVMLLNQRTLDEARFWLAGSLSGRTLDVLWPVLPTLLLGLVVALAVAPALNALALGD
                     DAAQALGVPVARIRLAGGVAVVLLAGSAVAVAGPVAFVGLAAPHLVRPLLGGDHRLLVP
                     GCLIAGPLLLLSADVLGRLVIRPSELEVGIVTAFLGAPLLALLARRVGR"
     gene            9650..10699
                     /locus_tag="IE325_RS13820"
                     /old_locus_tag="GCM10018780_27920"
     CDS             9650..10699
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090702.1"
                     /locus_tag="IE325_RS13820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_27920"
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="WP_190070130.1"
                     /transl_table=11
                     /translation="MSAAVVSVRTKSASRVRVRRRVLLFGAIGLVLLFVLLTLSLTTGE
                     IPLPAGTALRALVGLGDSGDVLVVQQFRAPRAVAAIVAGAGLGAAGCVLQRLFRNPLAS
                     PDVMGITGGASLGAVALIAAGASQALIPLGALGGGLLAALLLGVFAWGSGLAVTRLVLT
                     GLAVQAGLAAAVNLMIVRFPAELAGSALQWTAGSVYGRTWTEVWGAGGAMVLALGAALL
                     MHRRLAVLDLGDDSAGALGLRTSAARLQLLVLAVVLASLAAALAGPVTFVALAVPHVVR
                     FLTGPPTVASLVLAGVTGAVLLLASDLVVQHLLPIEGLPVGAVTATLGAPWLLVLMLRQ
                     SSPVQRGRG"
     gene            10870..11688
                     /locus_tag="IE325_RS13825"
                     /old_locus_tag="GCM10018780_27930"
     CDS             10870..11688
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995630.1"
                     /locus_tag="IE325_RS13825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_27930"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_190070131.1"
                     /transl_table=11
                     /translation="MPATPNQLSTEGLDLRYGDRTIVGGLDLTLPGGAVTAIVGPNACG
                     KSTLLRGLSRLLAPASGTVMLDGADIHRMSARALALRMGLLPQQPVTPEAVTVEALVRL
                     GRYPHQRLLSPWSAADQKAVDEALERTGTASLRDQPVDQLSGGQRQRAWIALALAQDTE
                     LLLLDEPTTFLDLRHQLDVLDLVAALHAEAGRTVVMVLHDLGQAARYADHMVVLKDGRL
                     AAAGAPADVLDAELVKSVFDVDCRVIPDPETGTPLVVPKAGAVRRSAATA"
     gene            11726..12745
                     /locus_tag="IE325_RS13830"
                     /old_locus_tag="GCM10018780_27940"
     CDS             11726..12745
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995631.1"
                     /locus_tag="IE325_RS13830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_27940"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_190070132.1"
                     /transl_table=11
                     /translation="MFKRSPLRGIGRLIAVFLAVVLGTAVLAACGGEDSAKESDTANAA
                     KGSSAFPRTLKTVMGDVKVPSQPKRVVVLDTGELDDVTLLGIDPVGAVAPHFKTEGGFP
                     TYLDGELKDTVDVGPLLEPNLEKIASLKPDLILSSKVRHEKVYDKLSAIAPTVFTETTG
                     GVWKENLKVHAEALGLEKEAAAKLKEYETQAKALGEAVKKKDGGKMPTVSVVRFIAGPT
                     RLYQSNSYSGVVLDDIGFQRPKSQVSSDPEVTMKDVSPEQIDQADADLIFVTAADAEDK
                     TQKQQVVSNPVWKDLPAVKDGKVFEVPDETWMSGIGVQAAEEMLKDVAKATGVALPAK"
     gene            12829..14004
                     /locus_tag="IE325_RS13835"
                     /old_locus_tag="GCM10018780_27950"
     CDS             12829..14004
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018852068.1"
                     /locus_tag="IE325_RS13835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_27950"
                     /product="acetyl-CoA carboxylase biotin carboxylase subunit
                     family protein"
                     /protein_id="WP_190070133.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 1.2e-07, bitscore:
                     27.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLYLLALNPTDSVTEGFLPAASRLGLDVTVLTDQPDAHRGTHPD
                     IEVLECDVRDFRAVITRISTHHSPDAVFTNSDHLQTQAALAAAYFDLSGKDWRATLRCK
                     DKAEMRRRLAAAGVDTVWSAELTEPVAPADAPYPCVVKPREGVASEDVVLVDGPEELVA
                     HTKEILERRPGATLVVEEYLPGDLFTLETLGDGDLRHVLGGFHTELSPPPYFIEERLTF
                     VPAHPEPVVDQVLTQLDALGVGFGACHTEFVVHDGRARIIEVNYRAIGDQCDLLLARLL
                     EIPLFEHILRTHLGEPLPDDLAARRDGAARLEYPCADRAGTLVGAPTAADLDIDGVHLT
                     YRPLRAVGERHELYRTNRDYLGVLRATGNDQPAVDRAVADFLAERRWEIQP"
     gene            14001..15650
                     /locus_tag="IE325_RS13840"
                     /old_locus_tag="GCM10018780_27960"
     CDS             14001..15650
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020117198.1"
                     /locus_tag="IE325_RS13840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_27960"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_190070134.1"
                     /sec_met_domain="IucA_IucC (E-value: 2e-33, bitscore:
                     111.0, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPTTVTDSCETELLTRVLSALLREDVVGLRSRSTHERRPDGDW
                     LRLPVADGDALLLPVAEDGYQSAYAARLPLLLRESDGAELSSYDTVLAALRALAEPEDR
                     DGFDAFAEECRQTLETMRLHAATRAEVVEGLSTPGTGLAASLAYDTLAARLDHPVYPTA
                     RGRSGLDEKQLRAYAPEFHPRFALRWVAVPREAVTVEGTLPDLWPTDGHGTHVMLPVHP
                     LTVDALPPGTALTDQPHLDVVPTLSMRTVATVADPSLHLKLPLATATLGLRNKRTIKPG
                     TLADGAAGQRLVEAVIDREPRFKDLILHADETTYAHAGHELLAVLCRRYPAGLDDAVVV
                     PMAALLAQAPDGRLVLDDLADRFYGGDPLALLDAALTLLFDWQTTLFGHGIALESHQQN
                     ISLVLRPDGLRLLFKDNDGPRINSERLDAVLPGPWGFDDARIFGTDDGPVADVFTTITV
                     HLCAGAYAFGLPRYRRDLLDLVRRRLTEAIDRLGGDAAHVLRARVLEAAGLPVKAMVSA
                     GTLLSKERSGAADINKHYTTGPNYLLPSGGSV"
     gene            15647..16831
                     /locus_tag="IE325_RS13845"
                     /old_locus_tag="GCM10018780_27970"
     CDS             15647..16831
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995634.1"
                     /locus_tag="IE325_RS13845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_27970"
                     /product="MFS transporter"
                     /protein_id="WP_190070135.1"
                     /transl_table=11
                     /translation="MSAEALRMPASARGQVHAVAGCYFVASFAALGLPPYLTEILPELG
                     DRGARWAGVLYVVPTVFGALGAPLWGRLADRYGRKRLLLRAQLGLAVSFLLAGWADSLT
                     TFTVALVLQGILGGTFAASNGYLGATLQGPALSKALTLMQGSARAALVAAPIVVGSLSG
                     WLSPHRQYALLAVLPLTAALLLAALPEPERAREAERIPEAVDAAPPIVSLKTLYVLEFA
                     FVFSTVISFPYLIALVDDRLPGTSPALSGVLFALPHVCYLLAALPVHAAFRDRPRGGLA
                     LGFTCIALGLAGHGIAGSLTALIAVRLLLGAGLTLGLVCLSVLAADCAKGRAPGGLFGS
                     LEFFSKAGAVAAGVAAAAGSARFGPAAPVLIGGAAAAVTAIVLPTPHLRTRWSR"
     gene            16831..18567
                     /locus_tag="IE325_RS13850"
                     /old_locus_tag="GCM10018780_27980"
     CDS             16831..18567
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995635.1"
                     /locus_tag="IE325_RS13850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_27980"
                     /product="IucA/IucC family siderophore biosynthesis
                     protein"
                     /protein_id="WP_190070136.1"
                     /sec_met_domain="IucA_IucC (E-value: 2.7e-59, bitscore:
                     195.8, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSLTDSLPEQGTAPVVSAELPTADEVVAHTLLNCLLREVSGPEH
                     QSVVTDGRLLLRLPRRGVLLRVALRRTSLIGAHRFTGPVSEQRDGDWAEVDWRRLAEYT
                     HDELWLRTGVRNEEFLEQIVSSHDAVATALAAPRATKVADAYLSSEQSLLFGHRFHPTP
                     KARTGDPRAWSAYAPEVGASFPLRHLAVRDHLIAEEHADPASLAPLDRQRTDVPDGYRL
                     LPAHPWQYETLREHPLLRAALDRGDVLDLGPGGQPFAATASVRTLYDGETFLKFSLNVR
                     ITNCLRKNSSYELSGAVALTRALAPAFADLAERFPGSDMLREPAYRTLALPGPDGTPDR
                     ALFEGFGVIVREGLPSRLAPGTTPLLAAAVADEYPTGAAHLSRLLAGADEQAALDWWST
                     YLDLLLPPVLSAYFDHGLVLEPHLQNVLICVDGDGRPAQVLFRDLEGTKLVPDHHEDTL
                     GALPPDVAGPMTYDAQRGWDRVVYCLLVNHVAELLAALADLHPQAEAALWTRVRDTLRA
                     YAEDQGCPPRLAALLAGVPLPAKANLLTRWERKADREAGYVRLPSPLAEDILRDRTGGA
                     TR"
     gene            18564..19754
                     /locus_tag="IE325_RS13855"
                     /old_locus_tag="GCM10018780_27990"
     CDS             18564..19754
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090709.1"
                     /locus_tag="IE325_RS13855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_27990"
                     /product="type III PLP-dependent enzyme"
                     /protein_id="WP_190070137.1"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 1.9e-15,
                     bitscore: 52.0, seeds: 500, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 1.1e-26, bitscore:
                     88.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPLVHDRILSLAPTELPAYIYDLAALRAHAATVRDALPERVELY
                     YAAKANPEPEILGALGPYVDGYEVSSGGELAHVAGAAPGRPLAFGGPGKTPDEVTAALE
                     LGVERFHVESEYELRMLAELARLVAPGRRVAVLPRVNLPVADGSLAGSALAMGGRPTPF
                     GMDPVRAEPVIRQLADGTYPQLELRGIHAHLASGLEAAEQVAVAETVVSWATGLGVGLA
                     EVNVGGGMHVDYGAPERRFDWKSYGTGLARLLERHPTLTLRIEPGRALTAYCGWYATEV
                     LDVKHSHGEEFAVVRGGTHHLRTPATKGHDQPCSVLPVDDWPHPWPRPGAEGGRVTLAG
                     QLCTPKDVLAREVPAAGLRAGDRVAFALAGAYAWNISHHDFLMHPRPGFHFLGTAE"
     gene            complement(19866..20177)
                     /locus_tag="IE325_RS13860"
                     /old_locus_tag="GCM10018780_28000"
     CDS             complement(19866..20177)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016430675.1"
                     /locus_tag="IE325_RS13860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_28000"
                     /product="hypothetical protein"
                     /protein_id="WP_190070138.1"
                     /transl_table=11
                     /translation="MISTRRIAAAVGLAAGITGLAAPLASAAPVVAPKNAGTLNPVATL
                     DSLATTGVPADRRAEMPRPSEQLARIEQLKELARTQRPQEAKALDTPVTRMLPGALKF"
     misc_feature    20168..20182
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.95"
                     /tool="antismash"
     gene            20347..20712
                     /locus_tag="IE325_RS13865"
                     /old_locus_tag="GCM10018780_28010"
     CDS             20347..20712
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386648.1"
                     /locus_tag="IE325_RS13865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_28010"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_190070139.1"
                     /transl_table=11
                     /translation="MGTTATPSFNTDTLRRAVEGQSPDTLLSLYTDDAEIRLVNRNAQP
                     SHPKVLTGRNQISDMLTDVYNRDMTHKLEGCVVQGDQAAYSESCEYADGVRVMSESMIT
                     LRDGKISRQIIIEAWDE"
     gene            complement(20881..21873)
                     /locus_tag="IE325_RS13870"
                     /old_locus_tag="GCM10018780_28020"
     CDS             complement(20881..21873)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994949.1"
                     /locus_tag="IE325_RS13870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_28020"
                     /product="CU044_5270 family protein"
                     /protein_id="WP_190070140.1"
                     /transl_table=11
                     /translation="MADELELLRRANPVPVDGPHYGDGPLDHTAERHLDLLLHEHRPPA
                     PRRRTRLAWGLAASAVVAALVSALLFTGQTTAPAVAAPRPLVVRAESTPVSMARLAERA
                     EQAASQGSPELRKGTHVQSWSLAMSDQDPPITLPQERIVRWNSDDSHTELVVATDPRHP
                     GRPVLTDEGGAPRLVDDGHVLNRRTYPPSWSDAPPESPPPHDPEALHDYLEEAERAFLA
                     DHSQPLSTAELLDATEILLDHWTLGPRESAALARLLADAEGLRPVGRVTDRLGRHGQAY
                     VYDGEDSRRMLIMNPADGSVLGLEQTFTRDDPRYGVTAGDVMTYSAWMR"
     gene            complement(21866..22399)
                     /locus_tag="IE325_RS13875"
                     /old_locus_tag="GCM10018780_28030"
     CDS             complement(21866..22399)
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015655776.1"
                     /locus_tag="IE325_RS13875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_28030"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_190070141.1"
                     /transl_table=11
                     /translation="MSNDETFAAAYREHYWAVSRYVARRLDGRTSEVEEVVAEVFTVAW
                     RRRADLPDAPLPWLYGVARNCLANAVRGFGRRRRLVDRLGNDDAAHGRHLVDSPDAEAP
                     GAWVHEALARLSAADQEVLRLTAWEELGVEELAVALGCGTRAASMRLHRARRRLRAEID
                     RVSPTTAPKERSHG"
     misc_feature    complement(22504..22519)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.04"
                     /tool="antismash"
     gene            22505..24124
                     /gene="ctaD"
                     /locus_tag="IE325_RS13880"
                     /old_locus_tag="GCM10018780_28040"
     CDS             22505..24124
                     /EC_number="7.1.1.9"
                     /GO_function="GO:0004129 - cytochrome-c oxidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0015990 - electron transport coupled proton
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene="ctaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676702.1"
                     /locus_tag="IE325_RS13880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_28040"
                     /product="cytochrome c oxidase subunit I"
                     /protein_id="WP_190070142.1"
                     /transl_table=11
                     /translation="MKRIKDFKAVQWLTTTDHKTIGTLYLVTSFAFFVIGGVMALLMRA
                     ELARPGLQIMSNEQFNQAFTMHGTIMLLMFATPLFAGFANWIMPLQIGAPDVAFPRLNM
                     FAYWLYLFGSLIAVGGFLTPDGAADFGWFAYSPLSDAVRSPGIGADMWIMGLAFSGFGT
                     ILGAVNFITTIICMRAPGMTMFRMPIFVWNVLLTAVLVLLAFPVLAAALFALEADRKFG
                     AHVFDAANGGALLWQHLFWFFGHPEVYIIALPFFGIISEVIPVFSRKPMFGYMGLIAAT
                     IAIAGLSVTVWAHHMYVTGGVLLPFFSFMTFLIAVPTGVKFFNWIGTMWKGSLSFETPM
                     LWSFGFLITFVFGGLTGVMLASPPLDFPTSDSYFVVAHFHYVIFGTVVFAMFSGFHFWW
                     PKFTGRMLDERLGKMTFWTLFIGFHGTFLVQHWLGVNGMQRRIPDYLAVEGLTTLNTLS
                     TVFSFVLGASFLPFFYNIWKTAKYGEKVEVDDPWGYGRSLEWATSCPPPRHNFLRLPQI
                     RSESPAFDLHHAPERQKELTAL"
     gene            24121..24444
                     /locus_tag="IE325_RS13885"
                     /old_locus_tag="GCM10018780_28050"
     CDS             24121..24444
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995648.1"
                     /locus_tag="IE325_RS13885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_28050"
                     /product="hypothetical protein"
                     /protein_id="WP_190070143.1"
                     /transl_table=11
                     /translation="MSLTDEFLSDIEGHLLLAATREDGRTAAVRFSAPLHWLTDAQRDE
                     VERRFEAEYLALARVSWQRTEERAGTLRDEYEAIYRDLRRRLLAGWLLICALAVGVLAV
                     CLA"
     gene            complement(24455..26416)
                     /locus_tag="IE325_RS13890"
                     /old_locus_tag="GCM10018780_28060"
     CDS             complement(24455..26416)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020117191.1"
                     /locus_tag="IE325_RS13890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_28060"
                     /product="ricin-type beta-trefoil lectin domain protein"
                     /protein_id="WP_190070144.1"
                     /transl_table=11
                     /translation="MYPPPRTHLVRRCRSAVTRALVLTLTAAAALLFAGPAPAQAATTA
                     RQIPVPSAPMGWASWNAFAAKVDYNVIKKQVDAFVAAGLPEAGYEYINIDEGWWQGTRD
                     SAGNITVDEAEWPGGMKAIADYIHSKGLKAGIYTDAGKDGCGYYFPTGRPAAPGSGSEG
                     HYEQDMTQFSKWGFDFVKVDWCGGDAEKLDPKATYQAISDAVAAATATTGRPLALSLCN
                     WGYSNTWNWAPGMGPMWRTNTDIFFHGGTPSYSNVLTAFDRNIHPTAQHTGYYNDADMM
                     VAGMTGLTAAQNRSHMNRWAISGAPLLTGLDLTTLTAETASTLTNPEVIAVDQDPRGLQ
                     GVEVAEDTTGLQVYGKVLAGSGNRAVVLLNRTSTTQNMTVRWSDLGLTNASATVRDLWA
                     RQNVATTGTSYTTSVPAGGSVMLTVTGGTEQSASTYNGTDSFSGVVAGNAGLKTVEVSY
                     TNNTATARTATLVVNGQTSTKVSFPPTGSNPGNISVNVSLAKGNTNTISFSGAPTLEGI
                     VVRPLPGKNGTLITGTGSGRCLDINDNTIANGTDAQLWDCSAGQNQVWQYNSRKELVVY
                     GNKCLDAYNLGTTNGTRVVIWDCNGQNNQKWNLNSDGTLTNVNSGLCLDANGAATANGT
                     KLVLWTCNGQNNQKWTVS"
     gene            26626..27837
                     /locus_tag="IE325_RS13895"
                     /old_locus_tag="GCM10018780_28070"
     CDS             26626..27837
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1102: glycosyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020134758.1"
                     /locus_tag="IE325_RS13895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_28070"
                     /product="glycosyltransferase"
                     /protein_id="WP_190070351.1"
                     /sec_met_domain="MGT (E-value: 4.2e-32, bitscore: 107.0,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAGSRGDVAPYTGLGHALSRAGHEVTLVTHGCFEGLVAESGVRF
                     HPLPVDPRAELESERGRSLHRSGTGLGKLVRVVELARNLAGSLTDDMLTAARSSDALLL
                     APSTAPLGRVIAEGLSLPSIELPLQPLAPTREFAPAMLGGGSWGGLGNRLAGHGVNLAI
                     ERVFSAAVPDARARVGPARGRARPPRRGPVLHGFSPLVVPRPRDWDPHLRVTGYWWPYD
                     GDTRLPSELRDFLDAGPPPVFVGLGSATVPDPAGLSATVVRALRTAGLRGVIQRGWGGL
                     EAAGDDVLTIGEVPHSGLFPRMAAVVHHCGAGTTAAGLRAGVPAVPVPIQFDEGFWAAR
                     LVGLGVAPYALPLRRFTAEALTAAVRRVTGDPDYGRRARVLAEGLRAEDGTAPVLDAVH
                     RLGE"
     gene            complement(27859..28521)
                     /locus_tag="IE325_RS13900"
                     /old_locus_tag="GCM10018780_28080"
     CDS             complement(27859..28521)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006380313.1"
                     /locus_tag="IE325_RS13900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_28080"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_190070352.1"
                     /transl_table=11
                     /translation="MAGRLRAPSGRYGGKSAEERQAERRRRFLDAALRLFGGDPGYRGT
                     TVAALSEAAGLSTRQFYEEFRTLEDVLAALHLEVNAWAEEAVLSAVAEAENLPLAERAT
                     VIFRAYAANVTADPRRIRITFVEIIGVSARLEEQRLARRARWIDLVCAEVAAAVVRGEA
                     APRDYRLAVTAFIGSVNGLLHDWSAGWVDATLDEVVDELVKILLGILKPSGPPLAQV"
     misc_feature    28602..28616
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.18"
                     /tool="antismash"
     gene            28713..29963
                     /locus_tag="IE325_RS13905"
                     /old_locus_tag="GCM10018780_28090"
     CDS             28713..29963
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1173: WD-40
                     repeat-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040469.1"
                     /locus_tag="IE325_RS13905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_28090"
                     /product="YncE family protein"
                     /protein_id="WP_190070145.1"
                     /transl_table=11
                     /translation="MPAIRPRHLCSVAAALALTVSASATAASAADSSAALREVMFVGNN
                     WDGTADVIKSSGDFAKIGRVNVIPDKDERMAEINANPIKWIYFMAIRNSVGEGHDQFVD
                     DMYSTPDGKSVVVSRPSFADVVSLDLATGAVNWRFPVSGYRADHMAVSPDGKRVAVSAS
                     TSNTVHVLDIESGKELGKFGTGDKPHENIFTQDGKYIYNMAIGDVNTQTDAPWLDWTKG
                     DRRITVVDATTYQQVKVIDMRPKLDALGLTDYSDAVRPAVFSPDESKLYFQVSFFNGFF
                     EYDLATDKITRTKTLPKNPATSDDRTTFVNDSRHHGISMSPDGSKLCVAGTMDDYATVV
                     NRTTLQEGPLITASKPYWATVSGDGKSCVISESGTDQVTAIDFATGQKQVSVPVGDHPQ
                     RVRLGHVQSGWTSPSAS"
     gene            complement(29964..31163)
                     /locus_tag="IE325_RS13910"
                     /old_locus_tag="GCM10018780_28100"
     CDS             complement(29964..31163)
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_transf_28"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1102: glycosyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015655783.1"
                     /locus_tag="IE325_RS13910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_28100"
                     /product="glycosyltransferase"
                     /protein_id="WP_190070146.1"
                     /sec_met_domain="Glyco_transf_28 (E-value: 3.3e-17,
                     bitscore: 57.9, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRILIAAAGSRGDIAPYTGLGAGLREAGHDITVATTDAFASLVRE
                     AGLEFRSLPTRPGAQRGVESRRELMRTAAAFVTELGQGFADAVDDGTELLLLSATTAQL
                     GWHLAESRGIRTLGVHLQPNAPTGDFPPTVMGPRSLGRLGNRAAGRLALRMADRVYAEA
                     VTSLRHRLGLPPLTPSAMRRRQKRANRPVLHGFSTALVPRPSDWREGLDVVGTWWPYVA
                     PERRLPAEVEDFLAAGARPVFIGFGSMAAGHGERLSGIAVEALRSAGLRGIVQSGGAGL
                     AVDGDDVLTIGDVPHALLFPRTAAVVHHAGAGTAAAALRAGVPAVPVPVTADQPFWARR
                     LAAIGAATDPIPFASLTAERLADALGRAVRQEAYARAASVAARHMATEDGVDAVLKALG
                     "
     gene            complement(31160..31951)
                     /locus_tag="IE325_RS13915"
                     /old_locus_tag="GCM10018780_28110"
     CDS             complement(31160..31951)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019526384.1"
                     /locus_tag="IE325_RS13915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_28110"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_190070147.1"
                     /transl_table=11
                     /translation="MSYSVGQVSAFAGVTVRTLHHYDRAGLLSPSGRSGAGYRLYDDSD
                     LARLQQILFYRELGFSLDEIAEILKDPQANALEHLRSRVRQLSEEIGRLQRLAEVAEQA
                     IEVQQTGVELTPQERFDVFGEIVFDLSYATDAQLKWQDSAGQKESMARAAGHTKEDWRQ
                     LMGEAAVWRGELLAAFDEGEPADGERVMDLAEEHRLHIARWFTTCPPEMHRRIADDFAA
                     DPRAFALVVPPSQQRPGLAAYLCRAVHANAARRVDREEENG"
     misc_feature    complement(32470..32483)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
ORIGIN
        1 ccgccctgga acagggtgtc gccggtgaag acgacaccga ggccgggatc gtgcagacag
       61 accgcgccgg gcgcgtgccc cggcgtgtgc agcaccgtga ggtcggcgcc cgcggcctcg
      121 atgacctggc cgtccaggag atgggcgtcg gggtcgcggt ccgggtgggt catcttccac
      181 agcggcaggt cgtcggggtg cagccagatc gtggcgccgg tgcggtcggc cagggcgggg
      241 gcggcgtcga tgtggtcgtt gtgggcgtgg gtgcacacga tcgccgtcag gcggcggtcg
      301 ccgacggcct cggcgatggc gtcggcgtcg tgggcggcgt cgatgacgat cacctcgtgg
      361 tcgtcgccga ccagccacac gttgttgtcg acgtcccagg tgccgccgtc gagggtgaac
      421 tggccggagg tgacgaggcg ttcgacgcgg gcggcgcggg cggccatcag agcatcacca
      481 ccgagcgcag gacgtcgccg tggtgcatcc gctcgaaggc cttctccacg tcggtgagtt
      541 cgatggtctc ggtgacgaac gcgccgaggt ccagccgccc ctgctgatgc aggtcgatca
      601 gcatcgggaa gtcgcgagag ggcagacagt cgccgtacca ggaggacttg agcgcgccgc
      661 cgcggccgaa gacgtccagg agcggcagtt cgagcttcat ctctggggtg ggtacgccga
      721 cgagtacgac ggttccggcg aggtcgcggg cgtagaaggc ctgcttgtac gtctccgggc
      781 ggccgacggc ctcgatgacg acgtcggcgc catggccgcc ggtcagctcg cggatcgcct
      841 cgaccggatc ggtctccttg gagttgaccg tgtgcgtggc gcccatcgag cgggccttct
      901 ccagcttccg gtcgtcgatg tcgacggcga tgatcttcgc ggccccggcc aggttcgcgc
      961 ccgcgatggc cgcgtcgccg acgccgccgc agccgatgac ggcgaccgag tcgccgcggc
     1021 cgacattgcc ggtgttgatg gcggcgccga taccggccat cacgccacag ccgagcagcc
     1081 cggcaaccgc cgcggacacc gacgggtcga ccttggtgca ctgcccggcc gcgacgaggg
     1141 tcttctcggc gaaggctccg ataccgaggg cgggggagag ctcggtgccg tcggtgaggg
     1201 tcatcttctg cttggcgttg tgggtgttga agcagtacca cgggcgtccg cgcagacagg
     1261 cccgacaact cccgcacacc gcacgccagt tgaggatcac gaagtcaccg ggttcgacat
     1321 cggtgacccc ctcccccacc gactccacca cgcccgcggc ctcatggccc aggaggaagg
     1381 ggaagtcgtc gctgatgccg ccctgcttgt agtgcaggtc ggtgtggcag accccgcagg
     1441 cctgcacctg tacgacggcc tcgcccggcc ccggatccgg cacgacgatc gtctccacgc
     1501 gcacggcctc gtccttgccc ggtgcgatca cgccccgcac ttcctgcgcc atggtgctca
     1561 gcccttcctt ccgtggatct cggtccgctt ccgaccctag acgtaactga tcagtagagg
     1621 cacggcgtgg gggtcttcac atccgcatcc ggccacgcac cctgaatacc cccgggggta
     1681 ccctgctaag gtgggccata tacccccggg ggtaatttcc tccgggacgg cacgagcttc
     1741 gggcttcggg cttcgggctt cgggcttcgg gcttcaccag aacaggagag gagtgctgcc
     1801 gtgtacttcg tcgacaccat cgacgtgtca gggctgggca accgcggcta tctggcgggc
     1861 ggggcgcaca gcgccgtggt ggtcgatccg ccgcgcgaca tcgaccgggt gatcacggcc
     1921 gccgcacggc ggggtgtgcg catcacacat gtggtggaga cacacatcca caacgactat
     1981 gtgaccggcg gcctcgaact ggcacggctc accggcgccg cctatctcgt cccggccgcg
     2041 gcacgggtcg cctacgagcg ggtgccggtc gccgacgggg accgtacgcg catcgaggac
     2101 aacctggttc tgcgcgccct ggccactccc ggacacaccc cacatcacac gtcgtatgtg
     2161 ctggaggagg ccggacacgc cgtggccgtg ttcaccggcg gctccctgct gatcggcacg
     2221 gtcgggcggc ctgacctggt ggaaccgggg ctgaccgggc ggctggcgcg ggcgcagtac
     2281 gagtcggcgc ggcggctggc ggcggagctg ccggacgaga cggcggtgct gcccacgcac
     2341 ggcttcggca gtttctgttc ggcgacgcgg gcggacggtg gcgcggagac cacgatcggc
     2401 cgtgagcggc aggtcaacgc ggcgctcgtc aaggatgtcg agacgttcgt cgccgagctg
     2461 ctcgccggtc tcgacgacgt acccgcgtac tacgcccaca tggggccggc caacacacag
     2521 ggcccggctt cggtggatct gacgccgccc cgtccggccg acgccgagga gatcgcggcg
     2581 cgactggccg ccggggagtg ggtggtggat ctgcggcatc gggtcgcgtt cgccgaggga
     2641 cacgtctccg gcgcggtgaa cttcgaggcc gagggccagc tggccaccta cctcgcctgg
     2701 ctgctgccct ggggcaagcc ggtgaccctg ctcgccgaga cgcccgcgca gctcgccgac
     2761 gcccagcgcg aactggtccg cgtcggcatc gaccggccgg ccgcggtggc cacgggctcc
     2821 gtggcggact gggtacggcc gggcgagcgc ccgcgttcgt tcccgcgcgg cacgttcgcc
     2881 gacctggcgg cgcggaagga tgtcgtgacg ctcgacgtac ggcgcgactc ggagcgccag
     2941 gccgaccaca tcaaggggtc ggtccacatc ccgctccacc agctgcgcga ccgtctctcc
     3001 gagattccgg acggcaccgt ctgggtgcac tgtgccggcg gcatgcgggc cgcgatcgcc
     3061 gcctcgctgc tcgacgcggc gggacgcgat gtcgtcgccg tcgacgactc cttcgacgcg
     3121 gcccgcacgg ccgggctccc gatggcccgt gtcacaccgg ccgaggcgca ggagcgggcc
     3181 gggtcgggcg cggtcctcgt ggacgtccgt gaggcgctgg agtgggccga gggccacgcc
     3241 cccggcgccg tccttgctcc cctctccgcc ctgaccgccg gcgcgtccct ccccgactcc
     3301 gcacaggccc gcccggtcgt cgccatctgc cgctcaggca agcgctcccg cgaggccgcg
     3361 gccctgctct cggcacgcgg tgtcgaggtc gtggacgtga tcggcgggat gggtgcctgg
     3421 acggaggccg ggcttcccgt ggtggccgag ccggagtccc gcgtggcggc ggagtccggg
     3481 gcgcccggtg ccgagtgaca ccgtccacct cgccgcaggt gactccgacc accaccacgc
     3541 cgggcccctg aaggggcgcg gcccctacca ccaccccgca gactcaccct cgctcatcac
     3601 cgcatctgcc gcgcgaggcg tcccgggccg ggaacccgga gccctctcat gaccgccctt
     3661 ctcctcggcc tcatggccgg tggtgtcacc gggctcgcgc tgggggcgtt gggtgggggt
     3721 gggagtgtgc tggccgtgcc ggcgttgatc tatctgctcg gtttcactcc ggccgccgcg
     3781 gcgacggcga gcctggtcgt ggtcgctttg acctccgcca ccgcgctcgc cgcgcacgcc
     3841 cgtgcgggca cggtgcgctg gcggggcggg gccgtgttcg cggcggcggg gctcgtgccc
     3901 gcggcggtcg gtggcgtggt gtccgggtgg ctgtcggaca ggctgctcac cggcgcgttc
     3961 gcggtgatcg ccgctgtcgc cgcactgcgg atgctgcggc cgtcggcgtc cgtacggcac
     4021 gaggaggtgc cggtgcggcc ctggcaggtc gcccgggccg gggcgggact cggcgcggtt
     4081 accggagtgc tcggagtggg cggcggcttc ctcgccgtac cggcactggt gagcgtggtg
     4141 ggtctgcgga tgcgggccgc cgtggggacc agtctgctgg tcatcacggt caactcactg
     4201 gccgcgctgg ccgcgagagc cggctccgat gcgcggatcg actggctcgc cgtggccccg
     4261 ttcgcggcgg ccgccgtgct cggcgcctgg gacggcaagc ggctcgccac gaaggtctcc
     4321 ggcgacagac tgcggcagat cttcgcctgg gccctgctcg cggtggccct gttcatgctg
     4381 gcggacgcca tgacatgacg cccgcacgcg ggacgcacgc cacgcgcccg tcccgcacct
     4441 acgccagcga caggaacagc ttctccagcc gggccttcat ctgctccgac gtctccccgt
     4501 tgtcccggcc ccgctcgggg tcggcgatgc actgctgcaa ccccgtcgcg atgatcgcga
     4561 agccggcccg gtcgagggca cgcgaggcgg cggcgagctg ggtgaccacg tcctcgcagt
     4621 cgcggccctc ctcgatcatc ttgatcacac cggagatctg cccctgcgcc cggcgcagcc
     4681 ggttgagcac cgacttgagg tcatcgccct cgaactgaag ctccacgatc actctcctct
     4741 acataccctt gggggtattt tacccctccc cggaaaggat ctcattcccc atgtcttctc
     4801 ccctggcccc gcgcgccctc gacatcgacg gcgcccgcac ccgactgccc gccctgaccg
     4861 tcatcgacgt ccgcaccccc ggtgagtacg ccgccggtca tcttcccggc gccctcaaca
     4921 tccccctgga ccggctcggc cgcgccctgc ccacgctcgc cgagcgaccg ggcggcgagc
     4981 tgctgatcgt ctgcgcctcc ggggcccgtt ccgagaacgc ctgcaagctg ctcaccgagc
     5041 acggcatacc ggccatgacc ctgaccggcg gcacccaggg ctgggcggaa cgcggccacg
     5101 aactgcaccg cccggcgtcc gccccgcgca gcacctggtc catggagcgc caggtgcggt
     5161 tcacggcggg ctcgatcgtt ctggtcggcc tggggctcgg actcctgcat ccggcctggc
     5221 agttgctctc cgccggtatc gcgggcggcc tcgtcttctc ggcgctcacc aacacctgcg
     5281 gaatggcggc gatactgtcg aagctgccgc acaaccgccc acgccccgcc gacctcgacg
     5341 cgacactggc ggccctggcc gaacgggcgc agggggcgca gggggcatag agggcctagc
     5401 ggcatcccgg cgccccctca cctcaagaag tcccgcacac tccgccccag ccagcccctc
     5461 ctcgtccagg ccgtccccgc cgcccagcgg cagcaaccgg tgcggcacat ggacaagggt
     5521 ctcggcgacc tgccaggcgg acagtccggg gggccgggtt cgacgaggac gacgccgtca
     5581 agtccttccc ggtccagttc gaatccctcc gcatgccgcg tcggtccggg cggcgacctg
     5641 gaaactgacg gtgcgcctgc tggcgcttcc gccgcacgac gcgtacctcg ccgccctcac
     5701 cgtccgggcc cgcgcgatgc tcaccatgac tggacgctgc tcgcccggga ccggcgagcc
     5761 gcccgtggcg ctgtcggtcg ctggaaaccc gcaggcctgg cggaacgaag ccgacgtagc
     5821 ctgaatgctc cgtacgactc cgaggagccc cgtgagcatc gcagagaccc cagccacccc
     5881 ctccacctgg cggctgctcc tgggctacgt gcgcccgcac cggtggaccc tgctggcggg
     5941 tgccgtgctg tcgctggtca cgggcgccac ggggctgctt ctgccgctgg tggcaaggga
     6001 gttgatcgac gacctgtcgc acgaccgcgc catcaccggg gcgctgttga tcatgtcggc
     6061 gctggtggtc gcgaacgcgg cgctcggcgc gctgggttcg tacgtcctgc ggcgcaccgc
     6121 cgagtccgtg gtgctcggcg cgcggcgcgc actgtcgtcg tatctgctgc ggctgcgcat
     6181 caccgccgtg gaccgcagcg agccgggcga tctgatggcg cgcatcacct ccgacacgac
     6241 gctgctgcgg gaggtcacga ccgactcgct ggtgggcctc ggcacgggcg ggctcacgct
     6301 ggtggcgacg gtggtgatga tgggcctggt ggatcccgtg ctgctcgcgg tcacgctcgc
     6361 cgtgatcctg tgcgccggta cggtcctcgg ggtgatcgtg ccgcacatca acaaggccag
     6421 caggcaggcc caggacgcgg tcggagtgat gggggcctcg ctggaacgga tcctgggcgc
     6481 gctgcgcacc gtgaaggcgt ccggggctga gcaccgggag gagcggactc tgcacgaggc
     6541 cgccgaggag tcctggcggc agagcgtgcg ggccgccaag tggtcggccg cggcgggcaa
     6601 cacggccggg ctcgccatgc agatcgcctt catcacggtg ctcgcggtgg gcggtgcacg
     6661 ggtggcgacc ggcgcgatcg acatcggcac gctggtggcg ttcctgctgt acgtcttcta
     6721 tctgatgtcg ccgatccaac aggtcgtcgg cgcgatcacc cagtaccaga cgggctccgc
     6781 ggcgctcgcc cgcatccagg aggcactacg gctcccctcc gaaccggccg cacaacccgc
     6841 gccgttgccc acgaccgggg cggagcccgc cgcgctggcc ttcgaggatg tgcggttccg
     6901 gtacaccgag gagctgccgt acgtccatca cggggtgacg ttcgccgtgc ccgcgcaggg
     6961 catgacggcg ttcgtggggc cgtcgggcgc cggcaagacg accgtgttct cgctgatcga
     7021 gcggttctac gaccccgaga gcggcgtcat cacgctcgac gggcgtgacc tcgccgactg
     7081 ggagctgcct cagctccgtt ccgcgatcgg gtatgtcgag caggatgctc cggtgctgtc
     7141 cgggtccctg cgggccaatc tgctgctcgg caatcctgac gccgatgagg aggccgtgac
     7201 gcgggtgttg aagacgaccc ggctggacgg gctggtcgcg cggctgccgg aggggctgga
     7261 gacgcttgtc gggcatcggg gcacgaagtt gtcgggaggt gagcggcagc gggtcgccat
     7321 cgcgcgggcg ttgttgcggc ggccacggct gctgctgctc gacgaggcga cctcgcagtt
     7381 ggacgcggtg aatgaggcgg cgctgcggga cacggtcgcc gatgtcgctc gtacgaccac
     7441 ggttctcgtc gtcgcgcatc ggctgtccac ggtcacgatg gctgatcgga tcgtggtgat
     7501 ggatgcgggg cgggtgcggg cggtgggtac gcatcgggag ctggtggccg gggatccgtt
     7561 gtatgcggag ttggcggcga cgcagttctt ggcgaccgcc gggtaagtgc ccggcccgtt
     7621 tcaggcttgg agcctgcgca ggcgttccgt gtcgcaggtg cggggacacg tcgcgcacgc
     7681 ctcgtcgggg cggatcgtgt agtacatgca gcagccggcc cgggtgcggg tcgggtgttg
     7741 gcggccgtcg tccgttgtca gatggcggaa gtcggcgcca cttggatacg gggaaacagc
     7801 cgtcggcaac aaccggctcg ccgccctcac cgcgtcgtcc tcgcggtcca gcatccggcc
     7861 gaggtaccag atgccggaga ccaggtcgtc gctgaccatg ccccacagtg cgcgtgagcg
     7921 gcggcgggcg gtcgggccga tcgcgtccag gagaggggcc atgtggtcgg cgacggccgc
     7981 tcgcaactcg gcttccaggg cctgctcgtg agggaccgtc agtacgccgg ggaggcgggc
     8041 cgccgggtcg tcgggcaggc aggccaggtc gctgccgggt gtgatggtga actcggccgt
     8101 ggtgaggtcg aggcgcagat cctcggggag gatccggggg acgcgctgtt cgaggtacca
     8161 ggcgccgctc atcaggagcg agaccgacca ggcgtagtcg tgcagggcgc gcgaggcagc
     8221 cacgtctcgg cgcggaaaca cgccgtagcg atcgtgaatg cgggccgcct ccgccgacac
     8281 gaaggcgtcg agcacggact cgtccttcac cagctccgcc gccgacacgc ccgtctgcgc
     8341 gtcctcggcg acccgcaccg acagcactcc gcacaggtcg gtgagccggc catagacgtc
     8401 accgagcgtg tgcgcgacgg cgccgacagg cggggaggtc gagggcacgg gcatcggtac
     8461 tccagtgcgg ggttccaacg aaagccgaac aggtaaggct taccttacaa tagcgatcaa
     8521 gcggagaacg ccaggtaggg cagttgcgag tgatcgacta tcgcgcacat cacagtgatc
     8581 acacagcaat tgaaatataa agcaagccta acctaagctc accgcttgtg actgcgaccc
     8641 aacggggcgc gcccaccggc gtgcccttcc gtgccctcag gcatgtaccg ctcttcctca
     8701 ccggcctcgc cgccctcgtg ctctgcgccg cgctgagcct cgcgctgggc gcccgctccg
     8761 tgccgctggg cacggtggcc gacgcgctgt tcggcaacgc tcacggccgc gaagccctcg
     8821 tggtgaccgg gctgcgcctg ccgagaaccg tcatcgggct cgcggtcggc gccgcgctcg
     8881 gggtcgccgg agcggtcgcc cagggcatca cccgcaatcc gctcgcctcg ccgacgacgc
     8941 tcggcatcaa cgcgggcgcc ggtttcgcgg tcgtcgtcgc catcttcgcg ctgaagctca
     9001 acagccctgc ccagtacgtg tggttcgcgt tcgccggcgc ggccggtgcc gccctgttcg
     9061 cccaggcgct ggcccgtcgc gccggggaca tcgacgccgt acggctcgcg ctgggcggca
     9121 cggtgctcca actcgtcctg ctgtcctgga cgtcggcggt gatgctgctg aaccagcgca
     9181 ccctggacga ggcccgcttc tggctcgcgg gatccctctc cgggcgcacc ctcgacgtac
     9241 tgtggccggt cctgccgacc ctgctgctcg gcctggtcgt cgcgctggcc gtcgcccccg
     9301 ccctcaacgc cctggccctg ggcgacgatg cggcgcaggc gctcggtgtg ccggtggccc
     9361 ggatccggct ggccgggggt gtcgcggtcg tcctgctcgc cggttcggcg gtcgcggtgg
     9421 ccggtccggt cgccttcgtc ggactggccg cgccccatct cgtacggccg ctgctcggcg
     9481 gcgaccaccg gctgctggtg ccgggctgtc tgatcgccgg tccgctgctg ctgctctctg
     9541 ccgatgtgct cggccgactg gtcatccgtc cctcggagtt ggaggtcggc atcgtgaccg
     9601 cgttcctcgg cgcgcccctg ctggccctgc tggctcggag ggtgggccga tgagcgccgc
     9661 cgtcgtgtcc gtgcggacca agtccgcctc ccgcgtgcga gtccggcgcc gggtgctgct
     9721 cttcggggcc atcggtctgg tcctgctgtt cgtgctgctc accctgtcct tgacgacggg
     9781 tgagatcccg ctgccggccg gtacggcgct gcgtgcgctg gtcgggctcg gggattcggg
     9841 ggacgtgctc gtggtgcagc agttccgggc gcctcgggcg gtggcggcga tcgtcgccgg
     9901 ggcggggctg ggggcggcgg ggtgtgtact gcaacgcctg ttccgcaatc cgctggcgtc
     9961 gcccgacgtc atgggcatca ccggcggggc gtccctgggc gccgtcgcgt tgatcgccgc
    10021 gggggcctcg caggcgctga tccccctcgg ggcgctcggg ggtgggctgc tcgcggccct
    10081 gctgctgggt gtgttcgcct ggggctcggg gcttgcggtc acgcggcttg tgctcaccgg
    10141 gcttgccgtg caggcggggc tcgccgctgc cgtgaacctg atgatcgtgc ggtttcctgc
    10201 ggagctcgcc gggtcggcgt tgcagtggac cgcggggtct gtgtacgggc ggacctggac
    10261 cgaggtgtgg ggagcgggcg gcgcgatggt gctggcgctg ggcgccgcgc ttctcatgca
    10321 tcggcggctg gccgtgctcg acctcgggga cgattcggcg ggggcgctgg ggttgcgtac
    10381 gtccgctgct cggcttcaac tgcttgttct cgccgtggtg ttggcctcgc tggctgcggc
    10441 gcttgccggg cccgtgacgt tcgttgcgct tgccgtgccg catgtcgtgc ggttcctgac
    10501 cgggccgccg acggttgctt cgctggtgtt ggccggggtc acgggggccg tgctgttgct
    10561 ggcctccgac ttggtggtgc agcacctgtt gccgatcgag gggctgccgg tgggggcggt
    10621 caccgcgacg ctcggggcgc cttggcttct ggtgttgatg ttgcggcaga gctcgcctgt
    10681 tcagaggggg cgcggatgac gaagcgttcc actgggggtg ccgggatggg cagtcgttcg
    10741 tccgcggcgc cgtcgtggct ggtcgcgccc gcacggcgga agccgcatgt ccaatacagc
    10801 cccgcgcccc tgaagggcga tccgctcacc cgatctgatg aacactcccc cggccttcag
    10861 gagccgcaca tgcccgccac ccccaaccag ctctccaccg aaggcctcga cctccgctac
    10921 ggcgaccgga ccatcgtcgg cgggctcgat ctgacactcc ccggtggtgc cgtcaccgcc
    10981 atcgtcgggc ccaacgcctg cgggaagtcg accctgttga ggggactgag ccgactcctc
    11041 gccccggcct ccgggaccgt catgctcgac ggtgccgaca tccaccgtat gtccgcgagg
    11101 gcactggccc tccgtatggg tctgctgccg cagcagccgg tcacgccgga ggcggtcacc
    11161 gtcgaggcgt tggtgcggct cggccggtat ccgcatcagc ggctgctgag cccttggtcg
    11221 gcggccgacc agaaggcggt cgacgaggca ctggagcgca ccggcaccgc ttccctccgc
    11281 gaccagcccg tcgaccagct gtccggcggg caacggcaac gcgcctggat cgcgctggcg
    11341 ttggcgcagg acaccgagct gctgctgctc gacgagccca ccaccttcct ggacctgcgg
    11401 caccagctcg acgttctcga cctggtggcc gctctgcacg ccgaggcggg ccgcaccgtg
    11461 gtgatggtgc tgcacgacct cggtcaggcc gcccgctacg cggaccacat ggtcgtcctc
    11521 aaggacggcc gcctcgccgc cgccggcgcc ccggcggacg tactcgacgc ggagctggtg
    11581 aagtccgtgt tcgatgtgga ctgccgggtg atccccgacc cggagaccgg caccccgctg
    11641 gtcgtcccga aagccggcgc ggtgcggcga tcagccgcga ccgcctgagc gctttcagca
    11701 ctccccactc acagaaagaa ccctcatgtt caagcgatcc cccctgcgcg gaatcggccg
    11761 gctgatcgcc gtgttcctcg ccgtcgtgct cggtacggcc gtgctggccg cctgcggtgg
    11821 cgaggactcc gcgaaggaga gcgacacggc gaacgcggcc aagggcagct ccgccttccc
    11881 gcgcaccctc aagaccgtga tgggcgacgt caaggtcccc tcgcagccga agcgggtcgt
    11941 cgtgctcgac accggtgagc tggacgacgt caccctgctc ggcatcgacc cggtcggcgc
    12001 ggtcgccccg cacttcaaga ccgagggcgg ttttccgacg tatctggacg gtgagctcaa
    12061 ggacaccgtc gatgtcgggc cgctgctcga gccgaatctg gagaagatcg cctccctgaa
    12121 gcccgatctg atcctttcct ccaaggtccg tcacgagaag gtctacgaca agctcagtgc
    12181 gatcgccccg accgtgttca ccgagaccac cggcggtgtc tggaaggaga acctcaaggt
    12241 ccacgccgag gcgctgggtc tggagaagga ggccgcggcc aagctcaagg agtacgagac
    12301 gcaggccaag gcgctcggtg aggccgtgaa gaagaaggac ggcggcaaga tgccgaccgt
    12361 gtccgtggtc cgcttcatcg ccggtccgac ccgcctctac cagtccaact cctacagcgg
    12421 cgtcgtactc gacgacatcg gcttccagcg cccgaagtcc caggtctcca gtgaccccga
    12481 ggtcacgatg aaggacgtca gcccggagca gatcgaccag gccgacgccg acctgatctt
    12541 cgtcaccgcc gccgacgccg aggacaagac gcagaagcag caggtcgtct ccaacccggt
    12601 gtggaaggac ctcccggccg tgaaggacgg caaggtcttc gaggtgccgg acgagacgtg
    12661 gatgtccggc atcggtgtcc aggccgccga ggagatgctc aaggacgtcg cgaaggccac
    12721 gggcgtggca ctcccggcga agtagctccc gctcactcct ccgggcgcgg gccgtaccaa
    12781 cggcccgcgc ccaacccccc acctgccagc gggagttgtc tctcagccat gcgcctgtac
    12841 ctgctcgccc tcaatccgac cgattcggtg accgagggct tcctgcccgc cgcgtcccgg
    12901 ctcggtctgg acgtcaccgt cctcaccgac cagcccgacg cccatcgcgg cacccacccg
    12961 gacatcgagg tcctggagtg cgacgtgcgc gatttccggg ccgtgatcac ccgcatctcc
    13021 acccaccact cccccgacgc cgtcttcacc aacagcgacc acctccagac ccaggccgcc
    13081 ctcgccgccg cctacttcga cctctccggc aaggactggc gtgccaccct gcgctgcaag
    13141 gacaaggccg agatgcgccg ccggctcgcc gcggccggtg tggacaccgt gtggtcggcc
    13201 gagctgaccg aaccggtcgc gcccgccgac gcgccgtacc cgtgtgtcgt caaaccgcgc
    13261 gagggcgtgg ccagcgagga cgtcgtcctc gtcgacggcc cggaggaact cgtggcgcac
    13321 accaaggaga tcctggagcg ccgcccgggt gccaccctgg tggtcgagga gtatctgccg
    13381 ggcgacctgt tcaccctgga gaccctcggc gacggcgacc tccgccatgt gctgggcggc
    13441 ttccacaccg agctgtcacc gccgccgtac ttcatcgagg agcgcctcac cttcgtcccc
    13501 gcccaccccg agccggtcgt cgatcaggtg ctgacgcagc tcgacgcgct gggtgtcggg
    13561 ttcggtgcct gtcacacgga gttcgtggtg cacgacgggc gggcgcggat catcgaggtc
    13621 aactaccgcg ccatcggcga ccagtgcgac ctgctgctgg cccggctgct ggagatcccg
    13681 ctcttcgagc acatcctgcg cacccacctg ggcgagcccc tcccggacga tctcgcggcc
    13741 cgtcgcgacg gcgcggcgcg gctggagtac ccgtgcgccg accgcgccgg caccctcgtc
    13801 ggcgccccca ccgccgccga cctcgacatc gacggcgtcc atctgacgta ccgtccgctg
    13861 cgcgcggtcg gcgagcggca cgagctgtac cgcaccaacc gggactacct cggcgtcctg
    13921 cgcgccaccg gcaacgacca gccggcggtg gaccgggcgg tggctgactt cctggcggag
    13981 cggcgctggg agatccagcc gtgaccgcgc cgacgaccgt gaccgactcc tgcgagacgg
    14041 aactgctgac gcgcgtgctg agcgcgttgc tgcgcgagga cgtggtcggg ctgcgcagcc
    14101 gttccacaca tgagaggcgg cctgacgggg actggctacg gctcccggtg gcggacggcg
    14161 acgccctgct gctgcccgtc gccgaggacg gctaccagtc cgcgtacgcc gcccggctcc
    14221 cgctcctcct ccgcgagtcc gacggtgccg aactctcgtc gtacgacacc gtcctcgccg
    14281 ccctgcgcgc gctcgccgaa cccgaggacc gggacggttt cgacgccttc gccgaggagt
    14341 gccgtcagac gctggagacg atgcggctgc acgcggcgac gcgggccgag gtcgtggaag
    14401 ggctgagcac gccggggacg ggcctggccg cgagcctggc gtacgacact ctcgccgccc
    14461 ggctcgacca ccccgtctat ccgacggcgc gcggccgctc gggcctggac gagaagcaac
    14521 tgcgggcgta cgcaccggag ttccatccgc ggttcgccct ccgctgggtc gccgtgcccc
    14581 gggaagcggt caccgtggaa ggcacactgc cggacctctg gcccacggac gggcacggca
    14641 cccacgtcat gctgccggtc catccgctga ccgtcgacgc cctccccccg ggcacagcac
    14701 tcaccgacca accccacctc gacgtcgtac ccaccctctc catgcgcacc gtggcgacgg
    14761 tcgccgaccc ctccctgcac ctcaaacttc ccctagccac cgccacgttg ggcctgcgca
    14821 acaagcggac catcaagccg ggcaccctcg ccgacggtgc ggccgggcag cggctggtgg
    14881 aggcggtgat cgaccgggag ccccggttca aggacctgat cctgcacgcc gacgagacga
    14941 cctacgcgca cgccgggcac gagctgctcg ccgtcctctg ccgccgctac cccgccggcc
    15001 tcgacgacgc cgtggtcgtg ccgatggccg cgctgctcgc gcaggccccc gacgggcggc
    15061 tggtcctgga cgacctcgcc gaccgcttct acggcggcga cccgctcgct ctgctggacg
    15121 cggccctcac cctgctcttc gactggcaga cgaccctgtt cggtcacggc atcgcgttgg
    15181 agtcccacca gcagaacatc tcgctggtgc tgcgcccgga cggtctgcga ctgctgttca
    15241 aggacaacga cgggccgcgc atcaacagcg agcggctcga cgccgtgctc ccggggccgt
    15301 ggggcttcga cgacgcccgg atcttcggca cggacgacgg tccggtcgcc gacgtgttca
    15361 ccacgatcac ggtccatctg tgcgcgggcg cctacgcgtt cgggctcccc cggtatcgcc
    15421 gtgacctgct ggatctcgta cggcggcggc tgacggaggc catcgaccgg ctgggcggcg
    15481 acgcggcgca cgtgctgcgg gcccgggtgc tggaggcggc tgggctgccg gtgaaggcga
    15541 tggtgtcggc cgggacgctg ctgtccaagg agcgttcggg cgcggcggac atcaacaagc
    15601 actacacgac cggccccaac taccttctcc cttcgggagg ttcggtatga gcgccgaggc
    15661 gctgcggatg ccggcgtccg cgcggggtca ggtgcacgct gtggccggct gctacttcgt
    15721 ggcgtcgttc gccgcgctgg ggctgccgcc gtatctcacc gagatcctgc cggagctggg
    15781 tgaccggggt gcccgctggg cgggggtgct gtatgtggtg ccgacggtgt tcggcgcgct
    15841 cggcgccccg ctgtgggggc ggctcgccga ccggtacggg agaaaacggc tgctgctgcg
    15901 cgcccagttg gggctcgccg tgtccttcct gctcgcgggc tgggccgact ccctgaccac
    15961 cttcaccgtg gcgctggtgc tgcagggcat cctgggcggc acgttcgccg cgtccaacgg
    16021 ctatctgggc gcgaccctcc agggaccggc gctgtcaaag gcgctcacgc tgatgcaggg
    16081 cagtgcgcgg gccgcgctgg tcgccgcgcc gatcgtggtc ggctcgctgt cgggctggct
    16141 gtcgccgcac cgccagtacg ccctgctcgc cgtactgccg ctgacggcgg ccctgttgct
    16201 cgctgcgctg cctgaacccg agcgcgcgcg ggaggcggag cgcatacccg aggcggtcga
    16261 cgccgccccg ccgatcgtct ccctgaagac cctctacgtc ctggagttcg ccttcgtgtt
    16321 ctccaccgtc atctccttcc cctacctcat cgcgctcgtc gacgaccgcc tcccgggcac
    16381 ctccccggcg ctgtccggag tcctgttcgc gctgccccac gtgtgctacc tgctggcggc
    16441 gctgcccgtg cacgccgcct tccgggaccg tccgcgcggc gggctcgcgc tcggcttcac
    16501 ctgcatcgcg ctcgggctcg ccggacacgg gatcgccggg tccctgaccg ccctgatcgc
    16561 cgtacggctg ctgctgggcg cggggctcac gctcgggctc gtgtgtctgt cggtgctggc
    16621 cgccgactgc gccaagggcc gggcgcccgg cgggctgttc ggttcgctcg agttcttctc
    16681 caaggccggc gcggtcgccg ccggcgtggc cgcggcggcg ggcagtgccc gcttcggacc
    16741 ggccgcaccc gtactgatcg gcggtgccgc cgccgctgtc acggccatcg ttctccccac
    16801 accgcacctg cgcacccgct ggagccgttg atgccctccc tgaccgactc gctccccgag
    16861 cagggcactg ccccggtcgt ctccgccgaa ctgcccaccg ccgacgaggt cgtggcccac
    16921 accctgctca actgcctgct gcgcgaggtc tccgggcccg agcaccagag cgtcgtcacc
    16981 gacggccggc tgctgctgcg cctgccccgc cgcggcgtcc tgctgcgcgt cgccctgcgc
    17041 cgtacgtcgc tcatcggggc gcaccggttc accgggccgg tgagcgagca acgcgacggc
    17101 gactgggcgg aggtggactg gcggcgcctc gccgagtaca cgcacgacga gctgtggctg
    17161 cggacgggcg tgcgcaacga ggagttcctg gagcagatcg tctccagcca cgacgccgtc
    17221 gcgacggccc tggccgcccc gcgcgcgacg aaagtcgcgg acgcctatct ctcctcagag
    17281 cagtccctgc tgttcggcca ccgcttccac cccaccccga aggcccgcac gggcgatccg
    17341 cgcgcctggt ccgcctacgc ccccgaggtc ggcgcgtcct tcccgctgcg gcacctcgcc
    17401 gtacgcgacc acctgatcgc cgaggagcac gccgacccgg cgtcgctcgc cccgctcgac
    17461 cggcagcgca cggacgtccc ggacggctac cgactcctcc ccgcccaccc ctggcagtac
    17521 gagacgctcc gcgagcaccc gctgctgcgc gccgccctcg atcggggcga cgtcctcgac
    17581 ctgggccccg gcggtcagcc gttcgccgcc accgcgtcgg tgcgcacgct gtacgacggg
    17641 gagaccttcc tgaagttcag cctcaatgtg cggatcacca actgcctgcg caagaacagc
    17701 agttacgagc tgtccggcgc ggtcgccctc acccgcgcgc tggcccccgc cttcgccgac
    17761 ctggcggagc gcttcccggg cagcgacatg ctccgcgagc ccgcctaccg cacgctcgcc
    17821 ctgcccggcc cggacggcac cccggaccgc gcgctgttcg agggcttcgg cgtgatcgtc
    17881 cgcgagggtc tgccgagccg gctcgccccg ggcaccactc ccctgctcgc cgccgccgtc
    17941 gccgacgagt acccgaccgg cgccgcccac ctgtcccgcc tcctcgccgg agcggacgaa
    18001 caggcggccc tcgactggtg gtcgacctac ctcgacctcc tcctcccacc cgtcctgtcc
    18061 gcctacttcg accacggcct ggtcctggag ccgcacctcc agaacgtgct gatctgcgtc
    18121 gacggcgacg gccggcccgc ccaggtcctc ttccgcgacc tggagggcac caagctggtc
    18181 cccgaccacc acgaggacac cctcggcgcg ctgccgccgg acgtggcggg tccgatgacg
    18241 tacgacgcgc agcgcggctg ggaccgggtc gtgtactgcc tgctggtcaa ccatgtcgcc
    18301 gagctgctcg ccgccctcgc cgacctgcac ccgcaggcgg aggccgcact ctggacccgg
    18361 gtccgcgaca cgctccgggc ctacgccgag gaccagggct gcccgccccg cctcgccgcc
    18421 ctcctcgccg gggtgccact gcccgccaag gccaacctcc tcacccgctg ggagcgcaag
    18481 gccgaccggg aggcgggcta cgtccggctg ccgtcaccgc tcgccgagga catcctgcgc
    18541 gacaggaccg ggggtgccac ccgatgacgc cgttggtcca cgaccgtatt ctgtccctcg
    18601 ccccgaccga actccccgcg tacatctatg acttggcagc cctgcgcgcc cacgccgcca
    18661 ccgtgcggga cgctctcccg gagcgggtcg agctgtacta cgccgccaag gccaacccgg
    18721 agccggagat cctcggcgcg ctcggcccgt acgtcgacgg gtacgaggtc tcctcgggcg
    18781 gcgaactcgc ccatgtcgcg ggggccgcac cgggacggcc gctcgccttc ggcggtcccg
    18841 gcaagacgcc ggacgaggtg acggccgcgc tggagctggg ggtcgagcgc ttccatgtgg
    18901 agagcgagta cgagctgcgc atgctggccg agctggcgcg gctggtggcg ccggggcggc
    18961 gggtcgcggt gctgccacgg gtcaatctgc cggtggccga cggctcgttg gcgggcagtg
    19021 cgctcgcgat gggcgggcgt ccgaccccgt tcggcatgga tccggtgcgg gccgagccgg
    19081 tgatccggca actggccgac ggcacctacc cccagctcga actacgcgga atccacgccc
    19141 acttggcgag cggactggaa gcggccgaac aggtcgcggt ggccgagacc gtcgtctcgt
    19201 gggcgacggg cctgggcgtc gggctcgccg aggtgaacgt cggcggcggt atgcatgtcg
    19261 actacggcgc cccggagcgc cgcttcgact ggaagtccta cggcaccggg ctcgcacggc
    19321 tcctcgaacg gcacccgacc ctgaccctgc gcatcgagcc gggccgggcg ctcacggcgt
    19381 actgcggctg gtacgccacc gaggtgctcg atgtgaagca cagccacggc gaggagttcg
    19441 ccgtcgtgcg gggcggcacg catcatctgc ggaccccggc gaccaagggc cacgaccagc
    19501 cgtgttcggt ccttccggtg gacgactggc cccacccctg gccacggccg ggtgccgagg
    19561 gcgggcgggt cacgctggcg ggacagctgt gcaccccgaa ggacgtcctg gcccgggagg
    19621 tgccggcggc cgggctgcgg gccggggacc gggtggcgtt cgcgctggcc ggggcgtatg
    19681 cgtggaacat ctcccaccac gacttcctga tgcacccgag gcccggcttc cacttcctgg
    19741 gaaccgctga gtagacagca ccgcttggta ggccgcaccg ctgggtagac agcacgtcac
    19801 tctaggcaca tgcgaagggc cgcccgcgtg agcggacggc ccttggggtg cggatgtgcg
    19861 gcgtctcaga acttgagggc gccgggcagc atccgggtga ccggggtgtc gagggccttc
    19921 gcctcctgcg gccgctgcgt ccgggccagc tccttgagct gctcgatccg tgccagctgc
    19981 tcggagggac gcggcatctc agccctgcgg tccgcgggca ctccggtcgt cgcgagcgag
    20041 tccagggtgg ccacggggtt gagcgttccg gcgttcttcg gggcgaccac cggagccgcg
    20101 ctcgccaggg gagcggcgag gccggtgata ccggccgcga gaccaacggc ggcggcgata
    20161 cgtcgtgttg agatcatgtt tacggcaacg cggtcggccc gcccccggac acggccgacc
    20221 ggtgcccctc acccgtcagg cccagcgcat cgcagcgctt gccgagcccc ccggtgcgga
    20281 ggactctcgg aggtgaggcc ctcgcggccg cccctcgtcc tgccgcgggc ctcgtaggag
    20341 gtcaccatgg gcaccaccgc aaccccgtcg ttcaataccg acacactgcg ccgggcggta
    20401 gaagggcaga gcccggacac gcttctctcg ctgtacacgg acgacgcgga gatccgcctc
    20461 gtgaaccgca acgcgcagcc gagccacccc aaggtgctga ccggccgcaa ccagatctcc
    20521 gacatgctca ccgacgtgta caaccgcgac atgacgcaca agctggaggg atgcgtggtc
    20581 cagggcgacc aggcggccta cagcgagtcc tgtgagtacg cggacggcgt gcgtgtgatg
    20641 tcggagtcga tgatcacgct gcgcgacggc aagatctccc ggcagatcat catcgaggca
    20701 tgggacgagt agggaggaca tggccgaagg tccaggtctc ggcccggctg acctggacct
    20761 tcagggcacg cgcggcggcg ggccggaccc gtccggtccg gcctcggcgg gcctggccga
    20821 tcgccgtggc gggtcgattg gtctccggcg ccatgtcacg gaaacggccg cctccgccgg
    20881 tcagcgcatc caggcgctgt atgtcatcac gtcgcctgct gtcacgccgt accggggatc
    20941 gtcccgggtg aaggtctgtt ccagtcccag gacggaaccg tcggcggggt tcatgatcag
    21001 catgcgtcgg ctgtcctcac cgtcgtacac atacgcctgt ccatgccggc ccagccggtc
    21061 cgtgacccga ccgacgggcc gcagcccttc ggcgtccgcc agcagccggg ccagcgcggc
    21121 ggactcgcgg gggccgagcg tccagtggtc gagcaggatc tcggtggcgt cgaggagttc
    21181 ggcggtggac aggggctggg aatggtccgc gaggaaggcg cgctcggcct cctccaggta
    21241 gtcgtgcaga gcctcggggt cgtgcggtgg cggggactcg ggcggggcgt cgctccaact
    21301 cggcgggtac gtccgcctgt tgaggacatg gccgtcgtcg accaggcgcg gtgcgccgcc
    21361 ctcgtcggtg aggaccggcc ggccggggtg acgcgggtcg gtcgccacga cgagctcggt
    21421 gtggctgtcg tcggagttcc agcgcacgat cctctcctgc gggagcgtga tcggcgggtc
    21481 ctggtcgctc atcgcgaggc tccaggactg cacgtgcgtg cccttgcgca gctcgggcga
    21541 gccctgcgaa gccgcctgct cggcgcgctc ggccagccgt gccatggata cgggcgtgga
    21601 ctcggcccgc acgaccagcg ggcggggcgc ggcgaccgcg ggggcggtgg tctggccggt
    21661 gaacagcagt gccgagacga gcgcggcgac gacggcggag gccgcgagac cccaggccag
    21721 ccgggtgcgg cggcggggag cgggcgggcg gtgctcgtgc agcagcaggt cgagatgccg
    21781 ttcggcggtg tggtccagtg ggccgtcgcc gtagtgcggg ccgtcgaccg gtacggggtt
    21841 ggctcggcgc aacagttcga gttcgtcagc catggcttcg ttccttgggc gcggtcgtcg
    21901 ggctcacacg gtcgatctcg gctctcagcc tgcggcgggc gcggtgcagc cgcatcgacg
    21961 cggcgcgtgt gccgcagccg agggcgacgg cgagttcctc gacgccgagt tcctcccaag
    22021 ccgtcagccg cagcacctcc tggtcggccg ccgacagccg ggccagcgcc tcgtgcaccc
    22081 aggcgccggg ggcctccgcg tccgggctgt ccaccaggtg ccggccgtgc gcggcgtcgt
    22141 cgttgcccag ccggtccacc agccgccgcc ggcgtccgaa gccgcgtacc gcgttcgcga
    22201 ggcagttgcg tgccacgccg tacagccagg gcagcggggc gtccgggagg tcggcccggc
    22261 ggcgccaggc gacggtgaac acctccgcca ccacttcctc gacctcactc gtacgcccgt
    22321 ccagtcgccg cgcgacatag cggctgaccg cccagtagtg ctcgcgatag gcagcggcga
    22381 aggtctcgtc gttgctcatg ttccgttcgt gtccggcacc ggccggatag tcacacccct
    22441 ttccgtgatt ctcgtcgcgt cggtcgagtg tgacgtgtgg gcggggcgcg gacacaggcg
    22501 gggcgtgaag aggatcaaag acttcaaggc cgtccagtgg ctgaccacca cggaccacaa
    22561 gaccatcggc acgctctatc tggtcacgtc gttcgcgttc ttcgtgatcg gcggtgtgat
    22621 ggcgctgctg atgcgcgccg aactcgcccg gccgggtctg cagatcatgt cgaacgagca
    22681 gttcaaccag gcgttcacga tgcacggcac gatcatgctg ctgatgttcg cgacgccgct
    22741 gttcgccggc ttcgcgaact ggatcatgcc gctgcagatc ggcgcgccgg acgtggcctt
    22801 cccccggctg aacatgttcg cctactggct gtacctgttc ggctcgctga tcgcggtcgg
    22861 cggcttcctc acgccggacg gcgcggccga cttcggctgg ttcgcctatt ccccactgtc
    22921 ggacgcggtc cgctcgcccg ggatcggcgc ggacatgtgg atcatgggtc tggccttttc
    22981 cggcttcggc acgatcctcg gcgcggtcaa tttcatcacc accatcatct gcatgcgcgc
    23041 gccgggcatg accatgttcc gcatgccgat cttcgtgtgg aacgtgctgc tgaccgctgt
    23101 attggtcctg ttggcgtttc ctgtgttggc ggcggcgctg ttcgccctcg aagcggaccg
    23161 gaaattcggt gcgcacgtct tcgacgcggc gaatggcgga gccttgctgt ggcagcacct
    23221 cttctggttc ttcggccacc cggaggtgta catcatcgcg ctgccgttct tcggcatcat
    23281 cagtgaggtc atcccggtct tctcccgcaa gccgatgttc ggctacatgg gtctgatcgc
    23341 ggcgaccatc gccatcgccg gcctgtccgt gacggtgtgg gcccaccaca tgtacgtcac
    23401 cggaggcgta ttgctcccgt tcttctcctt catgacgttc ctcatcgccg taccgaccgg
    23461 cgtgaagttc ttcaactgga tcggaacgat gtggaagggc tcgctctcct tcgagacccc
    23521 catgctctgg tccttcggat tcctgatcac cttcgtcttc ggcggcctca ccggggtcat
    23581 gctggcctca ccgccactgg acttcccgac ctcggacagc tatttcgtgg tcgctcactt
    23641 ccattacgtc atcttcggca cggtcgtctt cgcgatgttc tccggcttcc acttctggtg
    23701 gcccaagttc accggcagga tgctggacga gcggctcggc aagatgacct tctggacgct
    23761 gttcatcggc ttccacggca cgttcctcgt ccagcactgg ctgggggtga acggaatgca
    23821 gcgccggatt ccggactatc tggcggtgga ggggctgacg acgctcaaca cgctgtcgac
    23881 ggtcttctcg ttcgtgctgg gcgcgtcgtt cctgccgttc ttctacaaca tctggaagac
    23941 cgcgaaatac ggcgagaagg tcgaggtcga cgacccgtgg ggctacggcc gctcgctgga
    24001 gtgggcgact tcctgcccgc caccccgtca caacttcctc agactgccgc agatccggtc
    24061 cgaatccccg gcgttcgatc tgcatcacgc cccggagcgg cagaaggagt tgaccgctct
    24121 gtgagcctca ccgacgagtt cctcagcgac atcgaggggc atctgctgct cgccgcgacc
    24181 cgtgaggacg ggcgtacggc cgccgtgcgt ttcagcgcgc cgctgcactg gctgacggat
    24241 gcccagcggg acgaggtgga gaggcggttc gaggcggagt acctcgcact cgcccgcgtc
    24301 tcctggcagc gcactgagga gcgtgccggg accttgcggg acgagtacga ggcgatctac
    24361 cgcgacctgc ggcgcagact gctggccggt tggctgctga tctgcgccct ggccgtcggt
    24421 gtcctggccg tgtgcctcgc ttaggcatcc ggcgctagct caccgtccac ttctggttgt
    24481 tctgcccgtt gcaggtccag agcaccagct tggtgccgtt ggcggtggcg gcgccgttcg
    24541 cgtccaggca gagcccggag ttgacgttgg tgagggtgcc gtcgctgttc aggttccact
    24601 tctggttgtt ctggccgttg cagtcccaga tgacgacgcg ggtgccgttg gtggtgccga
    24661 ggttgtaggc gtcgaggcac ttgttgccgt agacgacgag ttccttgcgg gagttgtact
    24721 gccagacctg gttctgcccg gcgctgcagt cccacagctg ggcgtcggtg ccgttggcga
    24781 tggtgttgtc gttgatgtcg aggcagcggc cggacccggt gccggtgatc agcgtgccgt
    24841 tcttcccggg cagtggccgc acgacgatgc cttcgagggt cggggcgccc gagaaggaga
    24901 tcgtgttggt gttgcccttg gcgagggaga cgttgacgga gatgttgccg gggttggagc
    24961 cggtcggcgg gaaggagacc ttggtggagg tctggccgtt gacgacgagc gtggccgtgc
    25021 gggcggtggc cgtgttgttg gtgtaggaga cctcgacggt cttcaggccg gcgtttccgg
    25081 cgaccacgcc ggagaagctg tccgtgccgt tgtaggtgct cgcggactgc tcggtgccgc
    25141 cggtgacggt gagcatcacg gagccgcccg cgggcacgct ggtggtgtag ctggtgccgg
    25201 tcgtggcgac gttctgccgg gcccacaggt cacggacggt cgcggaggcg ttggtcaggc
    25261 cgaggtcgga ccagcggacg gtcatgttct gcgtggtcga ggtgcggttg agcaggacga
    25321 cggcacggtt gccgctgccg gcgaggacct tgccgtacac ctggagaccg gtggtgtcct
    25381 cggcgacctc gacgccctgg aggccgcgcg ggtcctggtc gacggcgatg acctcggggt
    25441 tggtgagggt gctcgccgtc tcggcggtga gggtggtgag gtcgaggccg gtgaggagcg
    25501 gggcgccgga gatcgcccac cggttcatgt ggctgcggtt ctgggcggcg gtcaggccgg
    25561 tcattcccgc gaccatcatg tcggcgtcgt tgtagtagcc ggtgtgctgg gccgtcgggt
    25621 ggatgttgcg gtcgaaggcg gtcagcacat tgctgtacga cggggtgccg ccgtggaaga
    25681 agatgtccgt gttggtgcgc cacatcgggc ccatgcccgg ggcccagttc caggtgttgg
    25741 agtagcccca gttgcacagg gagagggcga gcgggcggcc ggtggtggcg gtcgcggcgg
    25801 ccaccgcgtc gctgatcgcc tggtaggtcg ccttcgggtc gagtttctcg gcgtcaccgc
    25861 cgcaccagtc gaccttcacg aagtcgaagc cccacttgga gaactgcgtc atgtcctgct
    25921 cgtagtggcc ctcgctgccc gagccgggcg cggcggggcg accggtcggg aagtagtagc
    25981 cgcagccgtc cttgccggcg tcggtgtaga tgccggcctt cagacccttg ctgtggatgt
    26041 agtccgcgat ggccttcatg ccgcccggcc actccgcctc gtcgacggtg atgttgccgg
    26101 cgctgtcccg ggtgccctgc caccagccct cgtcgatgtt gatgtactcg tagccggcct
    26161 cgggcagccc cgccgccacg aacgcgtcga cctgcttctt gatgacgttg tagtcgacct
    26221 tcgcggcgaa ggcgttccag gacgcccagc ccataggggc gctcggcacc ggtatctgac
    26281 gggccgtcgt cgccgcctgg gccggggcgg gtccggcgaa cagcagagcg gcggccgcgg
    26341 tgagggtcag gacgagggca cgggtgacgg cggatctgca gcggcgcacg aggtgcgtgc
    26401 ggggaggggg gtacatgcgg ctccttgatg cgggggaaga cacaggagat caaaatgttc
    26461 ggaatttcga acgcaattcg ggacatcgaa cgcgtggcgc cgaaagtaga gcccctagga
    26521 gggcgcagtc aacggctggg acagacctga agtcgcccgt tcgcgccgct acttggcacg
    26581 tacgacgtcc ggcgccgcca tactggccct gtgcgcgtag cgatcatgac ggcgggctcc
    26641 cggggcgatg tggcccccta caccggactg ggccacgccc tgtcccgggc cgggcacgag
    26701 gtgaccctgg tgacgcacgg ctgcttcgag gggctggtcg cggagtcggg cgtacggttc
    26761 cacccgctgc cggtggatcc gcgggcggag ctggagtccg agcgcgggcg gagtctgcac
    26821 cgcagcggga ccgggctggg caagctcgtg cgtgtcgtgg agctggcacg caatctcgcc
    26881 gggtcgctga cggacgacat gctgaccgcc gcgcggtcga gcgacgccct gctcctggcc
    26941 ccgtccaccg cacccctggg acgcgtcatc gccgagggcc tgtccctgcc cagcatcgaa
    27001 ctgccactcc agccactggc tcccacaagg gagttcgcac cggcgatgct cgggggcggc
    27061 tcctggggcg gcctcggcaa ccggctggcc gggcatggag tgaacctggc catcgagcgg
    27121 gtcttctcgg cggcggtacc ggacgcacgc gccagggtcg gaccggcccg cggccgggca
    27181 cgcccgccgc gaaggggccc tgtactgcac ggcttcagcc ccctggtggt gccccgcccg
    27241 cgcgactggg acccgcatct gcgggtgacg ggctactggt ggccgtacga cggcgacacc
    27301 cgactcccct ccgagctgcg ggacttcctc gacgccggac cgccgccggt gttcgtgggc
    27361 ctgggcagcg cgaccgtccc ggatccggcg gggctgagcg ccacagtggt gcgagccctg
    27421 cgaacggccg ggctgcgggg cgtgatccag cggggctggg gtggcctgga ggccgccggg
    27481 gacgatgtgc tgaccatcgg cgaggtgccg cactccgggc tgttcccgcg catggccgcc
    27541 gtggtccacc actgcggggc gggcacgacc gccgccgggc tgcgcgcggg ggtgccggcg
    27601 gtgccggtgc cgatccagtt cgacgagggc ttctgggccg cccgcctggt cggcctcggc
    27661 gtggcaccgt acgccctgcc cctgcggcgc ttcacggccg aagcactgac ggcggccgtg
    27721 cggcgcgtga ccggggatcc ggactacggc cgtcgcgccc gggtcctcgc cgagggactg
    27781 cgggccgagg acggcacggc tccggtgctc gacgcggtgc accggctcgg cgagtgaatc
    27841 gcccgggccg cccgcgtctc agacctgggc gagcggtggc ccggacggct tgaggatgcc
    27901 gaggaggatc ttgacgagtt cgtcgacgac ctcgtcgagg gtcgcgtcca cccacccggc
    27961 gctccagtcg tgcagcagcc cgttgacgct gccgatgaac gccgtcacgg cgagacggta
    28021 gtcgcgcggc gccgcctccc cgcggacgac cgcggccgcc acctcggcgc agaccaggtc
    28081 gatccagcgg gcacggcggg ccaggcgctg ctcctccagg cgagcgctga cgccgatgat
    28141 ctcgacgaag gtgatccgga tacggcgtgg atcggcggtg acgttggcgg cgtacgcgcg
    28201 gaagatcacc gtggcgcgct cggcgagcgg caggttctcc gcctccgcga cggcggacag
    28261 cacggcctcc tccgcccatg cgttgacctc cagatggagg gcggccagta cgtcttcgag
    28321 ggtgcggaac tcctcgtaga actgacgcgt cgacagcccg gcggcctcgc tcagcgccgc
    28381 cacggtcgtg ccccggtagc ccgggtcgcc gccgaacagc cggagcgcgg cgtcgaggaa
    28441 gcgccgccgc cgctcggcct gtcgctcctc ggccgacttg ccgccgtagc ggccgctggg
    28501 cgccctgagc ctgcccgcca cactgtcctc ccgccgcttc accgatccga cggccaattt
    28561 tgtcgtgtac gcggtcttgt ggagaagggc accccctcct tacttttcag taagttgact
    28621 ctgaaagcac ttgtgttcag attcaccgcc ccgctttggc atgccccact catgacgccc
    28681 gcccacccct ttcagaggaa gagagagcag tcatgcctgc catcagaccc aggcacctgt
    28741 gctccgtagc cgccgccctc gccctgaccg tctccgcctc cgcgaccgcc gcctccgccg
    28801 ccgactcctc cgccgccctg cgcgaggtga tgttcgtcgg caacaactgg gacggcaccg
    28861 ccgacgtcat caagtcgtcc ggcgacttcg cgaagatcgg ccgggtcaat gtcatccccg
    28921 acaaggacga gcggatggcg gagatcaacg cgaacccgat caagtggatc tacttcatgg
    28981 cgatccgcaa cagcgtcggc gagggccacg accagttcgt cgacgacatg tactcgaccc
    29041 cggacgggaa gtcggtcgtc gtctcgcgcc cgagcttcgc cgacgtggtc tccctcgacc
    29101 tggccacggg cgcggtcaac tggcgcttcc ccgtgtccgg ttatcgcgcc gaccacatgg
    29161 cggtctcccc cgacggcaag cgggtcgccg tgtcggcctc gacctccaac accgtgcacg
    29221 tcctggacat cgagagcggc aaggagctgg gcaagttcgg caccggcgac aagccgcacg
    29281 agaacatctt cacccaggac ggcaagtaca tctacaacat ggcgatcggc gatgtgaaca
    29341 ctcagaccga cgccccctgg ctggactgga cgaagggcga ccggcgcatc acggtcgtcg
    29401 acgcgaccac gtaccagcag gtcaaggtca tcgacatgcg gcccaagctg gacgcgctcg
    29461 gcctcacgga ctactcggac gcggtccggc cggccgtgtt ctcgccggac gagtcgaagc
    29521 tgtacttcca ggtgtcgttc ttcaacggct tcttcgagta cgacctggcc accgacaaga
    29581 tcacccgcac caagaccctg ccgaagaacc cggcgaccag cgacgaccgc accacgttcg
    29641 tcaacgactc gcgccaccac ggcatttcga tgagccctga cggcagcaag ctgtgcgtcg
    29701 cggggacgat ggacgactac gccacagtcg tcaatcgcac cacgctccag gagggcccgc
    29761 tcatcaccgc ctccaagccc tactgggcca cggtcagcgg tgacggcaag tcctgtgtga
    29821 tctccgagag cggcaccgac caggtgaccg ccatcgactt cgccaccggg cagaagcagg
    29881 tgtcggtgcc ggtcggtgac catccgcagc gggtccgcct cggccatgtg cagagcggct
    29941 ggacgagtcc ctcggcgagc tgatcagccc agggccttca ggaccgcgtc caccccgtcc
    30001 tcggtcgcca tgtgccgtgc ggcgaccgag gcggcacgcg cgtacgcctc ctgccgcacg
    30061 gcccggccga gcgcgtcggc gagccgttcg gcggtgaggg aggcgaacgg gatcgggtcg
    30121 gtggccgccc cgatcgcggc gagccgccgt gcccagaacg gctggtcggc cgtcaccggc
    30181 accgggacgg ctggcactcc ggcacgcagg gctgccgccg cggtgcccgc cccggcgtga
    30241 tgcaccacgg cggccgtcct cgggaacagc aaggcgtgcg gtacgtcgcc gatggtcagg
    30301 acgtcgtcac cgtcgaccgc gagtccggcg ccgcccgact ggacgatgcc ccgcagcccg
    30361 gcgctccgca gcgcctcgac ggcgatcccg ctgagccgct cgccatggcc ggccgccatg
    30421 ctgccgaagc cgatgaacac cgggcgcgct ccggccgcga ggaagtcctc cacctcggcg
    30481 ggcagccgac gctccggtgc gacgtacggc caccaggtgc cgacgacgtc gagcccttcg
    30541 cgccagtcgg acggccgggg caccagcgcc gtgctgaagc cgtgcaggac gggccggttc
    30601 gcccgcttct ggcggcggcg catcgcggag ggagtgagcg ggggaaggcc gagacggtgg
    30661 cgtagcgatg tgaccgcctc ggcgtagacc cggtcggcca tgcgcagggc aaggcgtccg
    30721 gcggcgcggt taccgaggcg gcccagggaa cgagggccca tcacagtggg cgggaagtcg
    30781 ccggtggggg cgttgggctg gaggtggacg ccgagcgtcc ggatgcctct ggactcggcg
    30841 agatgccagc cgagctgggc ggtggtcgcc gacagcagca ggagttccgt gccgtcgtcc
    30901 accgcgtcgg cgaagccctg gccgagctcg gtgacgaacg cggcggcggt gcgcatgagt
    30961 tcgcgcctgc tctcgacgcc gcgctgcgct cccgggcggg tgggcaggct ccggaactcc
    31021 aggcccgcct cccgcaccag cgacgcgaag gcatccgtcg tggccacggt gatgtcgtgc
    31081 ccggcctctc gcaggcccgc cccgagaccc gtgtaggggg cgatgtcgcc acgtgatccg
    31141 gcggcggcga tcaggatcct catccgttct cctcctcacg gtccacccgg cgggccgcgt
    31201 tcgcgtggac ggcccggcac agataggcgg cgaggccggg ccgctgctgc gagggcggga
    31261 cgacgagcgc gaaggcgcgt ggatcggcgg cgaagtcgtc cgcgatccgc cggtgcatct
    31321 cgggcgggca ggtggtgaac cagcgggcga tgtgcagccg gtgttcctcg gcgagatcca
    31381 tgacccgctc gccatcggcg ggttcaccct cgtcaaaggc cgcgagcagt tcgccacgcc
    31441 agacggcggc ctcgcccatg agctgccgcc agtcctcctt ggtgtggccg gcggcgcggg
    31501 ccatcgactc cttctggccc gccgagtcct gccacttcag ctgggcgtcg gtggcgtagg
    31561 agaggtcgaa gacgatctca ccgaagacgt cgaagcgctc ctgcggggtg agttccacgc
    31621 ccgtctgctg gacctcgatc gcctgctcgg cgacctccgc cagccgctgg agccgcccga
    31681 tctcctcgct caactgcctt acgcgggatc ggagatgctc cagggcgttg gcctgtgggt
    31741 ccttgaggat ctcggcgatc tcgtcgaggg agaagccgag ttcgcggtag aagaggatct
    31801 gctggagcct ggccaggtcg gagtcgtcgt acagccggta accggcgccg ctgcgaccgc
    31861 tgggcgagag cagtcccgcc cggtcgtagt ggtgcagcgt gcgcacggtc accccggcga
    31921 aggccgagac ctgccccacg gagtagctca ttcacctgcc ctttcgtcgg gacacagcgt
    31981 gcagcctgac gtaaggggag ggtcaaacgg tgttcgtcac ccggcgttcc gcgccgccca
    32041 ggcggagagt tcggaccgtg cggcgttcag cagcgtggcc gagggagcgg tcgccccgtt
    32101 ggtgaccagc gcgtagtgca gcaccccgga gtccgtgtcg gtgagcagca gacggcggct
    32161 gccggtgccg cccggttccg cggcgacgcc aaccggggtg gccggggtgt acgccggggg
    32221 cgcgtaagcg gtgcccaggt cggagaccac cgtggtggac ccggtcggga aggacgccgg
    32281 gaggtggagt tcggtcggtg ccgtgccgct gttggagcgc cacagcagca gcccgtactg
    32341 cccggatccc accagctgcg ccacgttcgg cagcgagctc ggcaccgggt tccaggtcag
    32401 ggtggtgttg ccgtcgcggg agcggtcctc gtaggtgaag gcgacgttcg tgccggaggt
    32461 ggcgctgggg tagatccggt cgagcagccg ggcgtcctgg cgcagcaccg gcttgcccga
    32521 gtcgtcgagg cgtacggcgg agaggtcctc gtcgttccag gcgtcgc
//
