LOCUS       NZ_BNBM01000003        30892 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces lanatus strain JCM 4588 sequence03, whole genome
            shotgun sequence.
ACCESSION   NZ_BNBM01000003
VERSION     NZ_BNBM01000003.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces lanatus
  ORGANISM  Streptomyces lanatus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 687919)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 61X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014655715.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 05:46:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,254
            CDSs (total)                      :: 9,172
            Genes (coding)                    :: 8,973
            CDSs (with protein)               :: 8,973
            Genes (RNA)                       :: 82
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 199
            CDSs (without protein)            :: 199
            Pseudo Genes (ambiguous residues) :: 0 of 199
            Pseudo Genes (frameshifted)       :: 83 of 199
            Pseudo Genes (incomplete)         :: 153 of 199
            Pseudo Genes (internal stop)      :: 16 of 199
            Pseudo Genes (multiple problems)  :: 50 of 199
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:57:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 657027
            Orig. end                         :: 687919
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BNBM01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..30892
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="betalactone"
                     /region_number="5"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..30892
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="chemical_hybrid"
                     /product="NRPS"
                     /product="betalactone"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..30892
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[20000:23858](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..23858)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            14..763
                     /locus_tag="IE325_RS11935"
                     /old_locus_tag="GCM10018780_24040"
     CDS             14..763
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010041683.1"
                     /locus_tag="IE325_RS11935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_24040"
                     /product="ABC transporter permease"
                     /protein_id="WP_190069761.1"
                     /transl_table=11
                     /translation="MSAALVNPAVLRSEVRLFRREPGALFWMLGFPTLLLAILGSIPAF
                     RETDPAFGGLRPVDGYVPVAVLLGLIVGGIQAMPQTLTGYRERGILRRMSTTPVRPSAL
                     LSAQMLLFGGAALVSALFALAVGRLAFDVRLPRQGFGYALALLLAVLVALALGAVISAL
                     SRTTKIAGAIGSAVFFPAMFCAGVWMPVQTMPDVLARIVGYTPFGAAAEALNQAAAGHW
                     PGWGHLGVLVAWTVLLTAGAARWFRWE"
     gene            789..2042
                     /locus_tag="IE325_RS11940"
                     /old_locus_tag="GCM10018780_24050"
     CDS             789..2042
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019074476.1"
                     /locus_tag="IE325_RS11940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_24050"
                     /product="sensor histidine kinase"
                     /protein_id="WP_190069762.1"
                     /transl_table=11
                     /translation="MTAADTDIERRWELIRGVGPYGLLMVGTLLALATAELTPGPAQRT
                     TVAALVVAGLVLQVWWGRARRTRPGPSTAGTVYYALRWALGFALTWLNPFFAFYAVTGY
                     FDSDELIPGRRLRWLGPFACSIAVSGSQAGGLPFKEPVQWAVFAGLLVVNNVILTVVGH
                     LTNQQEERSRARAATIAELERTNTALQQALDENAALHSQLLVQAREAGVADERRRLAAE
                     IHDTLAQGLTGIIAQLQVVANAPDLPTARTHLDRASALARHSLGEARRSVHNLAPVALE
                     NDGLPQALKSTVAEWAERTGVRADFTVTGTAEQLHDELSATLLRIAQEALSNASRHARA
                     TRLGVTLTFLGEEVILDIRDDGQGFDPLTLPERGHTGGFGLPGMRARAERMAGCLTVES
                     EPGRGTALSARVPLVRHE"
     gene            2035..2682
                     /locus_tag="IE325_RS11945"
                     /old_locus_tag="GCM10018780_24060"
     CDS             2035..2682
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019074477.1"
                     /locus_tag="IE325_RS11945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_24060"
                     /product="response regulator transcription factor"
                     /protein_id="WP_190069763.1"
                     /transl_table=11
                     /translation="MSSDESSISLLIVDDHPVVRDGLRGMFESAPGFVVLGEAAGGEEA
                     LERAAALDPDVILMDLRMPGGGGVAAIAHLTRIGARAKVLVLTTYDTDSDTLPAIEAGA
                     TGYLLKDAPRDELFTAVRAAAEGRTVLSPAVASRLVSAVRTPKAHGNEPLSAREREVLA
                     LVAKGTSNREIARELFISEATVKTHLTHLYAKLGVKDRAAAVATAYERGILG"
     gene            complement(2683..4929)
                     /gene="glgX"
                     /locus_tag="IE325_RS11950"
                     /old_locus_tag="GCM10018780_24070"
     CDS             complement(2683..4929)
                     /EC_number="3.2.1.196"
                     /GO_function="GO:0004133 - glycogen debranching enzyme
                     activity [Evidence IEA]"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="glgX"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CBM_48"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297: Pullulanase, type I"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020124580.1"
                     /locus_tag="IE325_RS11950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_24070"
                     /product="glycogen debranching protein GlgX"
                     /protein_id="WP_190069764.1"
                     /sec_met_domain="CBM_48 (E-value: 4.1e-20, bitscore: 67.1,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="Alpha-amylase (E-value: 2.2e-15, bitscore:
                     52.3, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSAAEQEAVAGAVAAEEGRPAAVVNGARRKAPGVPVWPGTPVPL
                     GARFRVGPDGVAGTNFALWAGGAEAVDLCLFDEEGKETRARLTELTHEIWHGFVPGVMP
                     GQRYGYRVHGRWDPWTGGRWNPAKLLLDPYARAVDGDFGLPPEVYGHVRDWPQQHVADT
                     VRDDRDSAPYVPKGVVVHDDDNWADDRRPKTPWADSVIYEVHVRGFTKLHPGVPEELRG
                     TYAGLAHPAAIEHLVKLGVTAVELLPVHQFAHEDHLLRKGLRNYWGYNSIGYFAPHAAY
                     AASGTTGQQVGEFKRMVRALHDAGIEVILDVVYNHTAEAGELGPTLSLKGIDNRGYYRL
                     QSDARRYADYTGCGNTLHVVQPHVLRLITDSLRYWVTEMGVDGFRFDLAAALARSMHDV
                     DMLSPFLAVIAQDPVLRRVKLIAEPWDVGSGGYQVGAFPPLWTEWNDRYRNAVRDFWRG
                     ALPDVRDLGYRLSGSSDLYAWGGRRPYASVNFVTAHDGFTLRDLVSYERKHNEANGEGN
                     RDGSDDNRAWNGGVEGETDDERVRALRRRQLRNLLTTLLLSTGVPMLVAGDELGRTQRG
                     NNNAYCQDNEISWLDWELLEEPGWKALFDLTARLIELRHRHPVLRRRAFFSGRAHSADG
                     LRDLAWFTARGTEMTERDWYAPAATLGMFLSGRDIPGRDERGAPIVDDSFLAVLHAGDR
                     PVSFVLPGPPWAERYEVVVDTSREEQGEAPGVEHPAGAGITVPGRAVLLLRVDG"
     protocluster    3324..30892
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[13323:23858](-)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(13324..23858)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="2"
     misc_feature    complement(5193..5207)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.36"
                     /tool="antismash"
     gene            5265..6491
                     /locus_tag="IE325_RS11955"
                     /old_locus_tag="GCM10018780_24080"
     CDS             5265..6491
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016432558.1"
                     /locus_tag="IE325_RS11955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_24080"
                     /product="Ig-like domain-containing protein"
                     /protein_id="WP_229911760.1"
                     /transl_table=11
                     /translation="MTHLQGRARRAGAVLAAVLTWAGLLAGCTGGGIGEMLGKGQASED
                     VIRVTPDDGSKGARPDDRLLVRVPSGRLESVEVVKSQDAQDTPVPGRISKDGLRWEPED
                     PRLALAAKYTIDAVALDGHGRRSARHTTFTTYVPDKRFIAYVTPEHRSTVGTGMIVSLE
                     FNREIQNRAAVERAVQVTAEPAVEIRPHWFGKARLDFRPRDYWKPGTKVTVSLRLRDVQ
                     GAPGAYGLQHRTFSFTVGRHQVSLVDAAEHTMEVRRDDELLASVPITAGAPKMTTYNGK
                     MVVTEMLELTRMNGATVGFKKKNGKGEYDIPDVPHAMRLTDSGTFLHGNYWADRSIFGQ
                     SNVSHGCVGLRDVKGGGSDTPAGWFFDRSLVGDVVEVVRSNDKKVAPDNGLGGWNMGWK
                     EWKAGSAVK"
     misc_feature    complement(6650..6665)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.09"
                     /tool="antismash"
     gene            6661..7893
                     /locus_tag="IE325_RS11960"
                     /old_locus_tag="GCM10018780_24090"
     CDS             6661..7893
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030261.1"
                     /locus_tag="IE325_RS11960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_24090"
                     /product="Ig-like domain-containing protein"
                     /protein_id="WP_190069766.1"
                     /transl_table=11
                     /translation="MNVRPISGASVDGRRRVGLAAVAGALLLTVTACGGGGGSDSGAGG
                     GKGGDAGAAQAKKSQAVVTIAPGDGAKSVDTSGALKVTAAKGKLTDVEVKDAKGNAIDG
                     KISGDGGTWTPSTHLAAATKYTVHAVAKDTDGLEAAKEADFTTLTPKNTFIGRFTPEDG
                     SKVGVGMPFSLRFDRGITNPEDVEKAISIKTEPAVEVAGHWFGNDRLDFRPEKYWKSGT
                     KVTVELNLDGVEGRDGVYGEQDKKVTFTIGRNQVSVVDVKTRKMKVTQDGKVVKTIPVT
                     TGKPGYDTWNGQMVMTEKFVETRMNGDTVGYDGEYDIKDVPHATRLTDSGTFIHGNYWG
                     GGAFGNYNASHGCIGLRDVKGAWDKGTPAAWFFDHSMVGDVVVVKNSADATVDPGNGLN
                     GWNMSWEKWKA"
     gene            7974..8741
                     /locus_tag="IE325_RS11965"
                     /old_locus_tag="GCM10018780_24100"
     CDS             7974..8741
                     /NRPS_PKS="Domain: ECH (4-246). E-value: 6.1e-74. Score:
                     240.3. Matches aSDomain:
                     nrpspksdomains_IE325_RS11965_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016432556.1"
                     /locus_tag="IE325_RS11965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_24100"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_190069767.1"
                     /transl_table=11
                     /translation="MTVNLEVAEGVGTLRLDRPPMNALDVATQDRLKELAEEATRRDDV
                     RAVVIYGGEKVFAAGADIKEMQAMDHTAMVLRARALQESFTAVARIPKPVVAAVTGYAL
                     GGGCELALCADFRIAGENAKLGQPEILLGLIPGAGGTQRLARLIGPSKAKDLIFTGRMV
                     KAEEARELGLVDRVVAPDQVYAEAHAWAARLAQGPAIALRAAKESIDTGLETDIETGLA
                     VERGWFAGLFATEDRERGMRSFVEEGPGKAKFL"
     aSDomain        7986..8711
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS11965_ECH.1"
                     /evalue="6.10E-74"
                     /label="IE325_RS11965_ECH.1"
                     /locus_tag="IE325_RS11965"
                     /protein_end="246"
                     /protein_start="4"
                     /score="240.3"
                     /tool="antismash"
                     /translation="LEVAEGVGTLRLDRPPMNALDVATQDRLKELAEEATRRDDVRAVV
                     IYGGEKVFAAGADIKEMQAMDHTAMVLRARALQESFTAVARIPKPVVAAVTGYALGGGC
                     ELALCADFRIAGENAKLGQPEILLGLIPGAGGTQRLARLIGPSKAKDLIFTGRMVKAEE
                     ARELGLVDRVVAPDQVYAEAHAWAARLAQGPAIALRAAKESIDTGLETDIETGLAVERG
                     WFAGLFATEDRERGMRSFVE"
     gene            9026..9529
                     /locus_tag="IE325_RS11970"
                     /old_locus_tag="GCM10018780_24110"
     CDS             9026..9529
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003997750.1"
                     /locus_tag="IE325_RS11970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_24110"
                     /product="ATP-binding protein"
                     /protein_id="WP_190069768.1"
                     /transl_table=11
                     /translation="MAGLEGVEHPRGNGRATAARWSPAVEDEAASKALELFGNPTEAEV
                     PLPSRPESAATARRLAQVVVLRQWGLTPKMTEDAVLLVSELVGNAVRHTGARVFGLRMR
                     RRRGWIRIEVRDPSRGLPCLMPVQEMDISGRGLMLVDKLADRWGVDLLPRGKTTWFEMR
                     VAER"
     misc_feature    complement(9562..9576)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.39"
                     /tool="antismash"
     gene            9647..10813
                     /locus_tag="IE325_RS11975"
                     /old_locus_tag="GCM10018780_24120"
     CDS             9647..10813
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003997749.1"
                     /locus_tag="IE325_RS11975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_24120"
                     /product="YncE family protein"
                     /protein_id="WP_190069769.1"
                     /transl_table=11
                     /translation="MNRTHRTLLAALGLLALAACGTESAKDTERPTQAAIPAPVKERAV
                     QGLPGMPPVLDPKDVYAADRPNLLSPVVKDFPSRVYVPNSDSDTVSVIDPKTYEVVETI
                     PVGRQPQHVVPSWDLKTLWVNNNRGHTLTPIDPKTGKAGEEVEVHDPYNLYFTPNGKYA
                     IVMASLDRELVFRDPHTMKRLKTEPVTCYGVNHADFSLDGRYFIVSCEFSGELLKVDTE
                     KMKVVGQQKLPFDGAMPQDVKVSPDGKKFYVADMMADGMWVLDGDKFSAPKLLPTGKGC
                     HGLYVSRDSREMYVSNRGEGTVSVYDFTRDELTKKWHLPEGGSPDMGGVSADGKVLWLS
                     GRYDSEVYAIDTRTGDELARIDVGEGPHGLAVYPQPGRYSLGHTGVFR"
     gene            10902..11528
                     /locus_tag="IE325_RS11980"
                     /old_locus_tag="GCM10018780_24130"
     CDS             10902..11528
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973537.1"
                     /locus_tag="IE325_RS11980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_24130"
                     /product="ADP-ribosyltransferase"
                     /protein_id="WP_190069770.1"
                     /transl_table=11
                     /translation="MITTRLRRRAAAAVLSLSAVLATTAATAPESVTSARPTAARAVPD
                     PAACPVQFDDPIEAAADRRVDVDRITPDPAWRTSCGTLYRADGRGPEIVFRDGFLPKDV
                     VNGQYDVEKYVLVNQPSPYVSTTYDHDLYKNWWKSGWNYYIDAPGGVDVNKTIGDTHKW
                     ADQFEVAFPGGIDRKYILGVCPVDKATKTEIMSDCQSNPHFEPWH"
     gene            complement(11482..12150)
                     /locus_tag="IE325_RS11985"
                     /old_locus_tag="GCM10018780_24140"
     CDS             complement(11482..12150)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020121117.1"
                     /locus_tag="IE325_RS11985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_24140"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_190069771.1"
                     /transl_table=11
                     /translation="MATLGEILDAAGRGVFPPADGGTTVVPQLCRRDAGVLSFTAHSVV
                     FVDEDPRWVYDTLDSLDCDRLAATMNPRFLSALLDRTGRTVETIDAMLVADPLPGEPPL
                     ALTEIEDADHPRITYARGRRDGVRAWTAEGGVVVTGRGIGGRLEVSVEVDEAVRHRGLG
                     RSLVTAARHLVTEPLWAQVTPGNARSMRAFQAAGYRAVGAEALLLSARARSAGCSGSRS
                     "
     gene            12256..12507
                     /locus_tag="IE325_RS11990"
                     /old_locus_tag="GCM10018780_24150"
     CDS             12256..12507
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020131380.1"
                     /locus_tag="IE325_RS11990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_24150"
                     /product="EF-hand domain-containing protein"
                     /protein_id="WP_190069772.1"
                     /transl_table=11
                     /translation="MTSSTTKRGGSVAQIDIEEARRQFERIDADGDGSITAAEFKTALA
                     QGGDWNVTEAVAEAIIKSRDLNGDKLLSFDEFWAYLSK"
     gene            complement(12554..13327)
                     /locus_tag="IE325_RS11995"
                     /old_locus_tag="GCM10018780_24160"
     CDS             complement(12554..13327)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014055577.1"
                     /locus_tag="IE325_RS11995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_24160"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_190069773.1"
                     /transl_table=11
                     /translation="MTVLRAQDVHVVRDGTPILRDVSVTVRAGEHWALLGANGAGKSTL
                     LALLGARIHPTRGTVEVLGRRLGRVDLRELRAYVGHVDPRHPLTAPLRVRDVVLTGLTN
                     SVAPLPRHRPTPAQRERADRLIETLGLRPHRDARWPTLSQGQRARTLIARALMPRPRLL
                     LLDEPATGLDLPGREQLIGALTELRLRHPELATVLVTHHLEELPPGTSHALLLREGRAL
                     AQGPVAEVLTGDQVGKCFDLPLALERRDGRWNVRA"
     gene            complement(13324..15021)
                     /locus_tag="IE325_RS12000"
                     /old_locus_tag="GCM10018780_24170"
     CDS             complement(13324..15021)
                     /EC_number="2.3.3.13"
                     /GO_function="GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675109.1"
                     /locus_tag="IE325_RS12000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_24170"
                     /product="2-isopropylmalate synthase"
                     /protein_id="WP_190069774.1"
                     /sec_met_domain="HMGL-like (E-value: 1.9e-68, bitscore:
                     226.1, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTNPSELWNPQRPSPMPQHRYRPFHERVHVPAEDRTWPSARIER
                     APLWVPVDLRDGNQALAEPMDTPRKRRFFELLVATGFKEIEVGYPSASRTEFDFVRHLV
                     AGAVPDDVTPVVFTPARPDLIDRTFEAIAGLPRAVVHLYIATSPVWRDVVLGRDRGAVW
                     RTVREAAERMARQAGDGVRFQFSPETFNLTEPDFVLELCDGLSELWDASPDRPVTHNLP
                     ATVEIATPNVYADQIEYIHRHLARRDSVILSVHPHNDRGTGVACAELAVLAGAQRVEGC
                     LFGNGERTGNVDLVTLAMNLYAQGVDPMLDFGDIDAVRAVVEDCNRLPVHPRHPYAGDL
                     VHTAFSGTHQDAISKGLAHHAYRATELGVPPGQAAWEVPYLPIDPADIGRSYEAVIRVN
                     SQSGKGGTAYLLRTHHGLDLPARMRADFSTVVQTATDDSGREITPKELGDLFRATYVID
                     DGEISLDAWSVQQDNSRGEHRFVCTLRIGDRTGDHEGTGSGPLSAFVDALGGAGFAVAV
                     IDYAEHPLGDGIAAYVECRVDGVTAWGAGQGPAASVQAVVSAVNRAVR"
     gene            15226..15924
                     /locus_tag="IE325_RS12005"
                     /old_locus_tag="GCM10018780_24180"
     CDS             15226..15924
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006139717.1"
                     /locus_tag="IE325_RS12005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_24180"
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="WP_190069775.1"
                     /transl_table=11
                     /translation="MPPSPLGALRPSPLVEQAAERLREQIAGGHWPVGTKLPGETTLAR
                     ELGVGRSTVREALRALAGAGLVQPRQGAGVFVLATEPAEDWPTRLRRAAVNDVYEVRMA
                     VEVHAARLAARRRTPEDVTAMEAALEARRAASTADDATFVEADITFHATVVAAAHNPVL
                     TDLFTEFTPVLRKGLVELLNLTGVRVHDPNTADGAHEALVRAVVAGDGEGAAEVLRGEL
                     QEPFGAMMGD"
     misc_feature    complement(15269..15284)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.95"
                     /tool="antismash"
     gene            complement(15929..16486)
                     /locus_tag="IE325_RS12010"
                     /old_locus_tag="GCM10018780_24190"
     CDS             complement(15929..16486)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010041747.1"
                     /locus_tag="IE325_RS12010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_24190"
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="WP_190069776.1"
                     /transl_table=11
                     /translation="MIRGIDVSAYQSSSYATDGLSFVFIKATEGRSYINPKLAAQTKRA
                     RDAGLVVGFYHFLWPGNLSAQADYFVSKAPEKAGDILAVDWETTSEGTHASNAEKDLFI
                     RKLKEKRPNNPVILYANRNYWLNVDTTSYAGDGLWIADYVTAGKPRIQAKWRFHQYTDN
                     PLDKNVANFSSKAALREWAENA"
     gene            complement(16617..18296)
                     /locus_tag="IE325_RS12015"
                     /old_locus_tag="GCM10018780_24200"
     CDS             complement(16617..18296)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075033.1"
                     /locus_tag="IE325_RS12015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_24200"
                     /product="DUF885 domain-containing protein"
                     /protein_id="WP_229911761.1"
                     /transl_table=11
                     /translation="MPRAEAGVHGVCDAYVDDYARLNPLAATEFGIRGHDAHLPDLSPD
                     GHAARAELARTALSDMAATRPGDDAERIAKAVFTERLTVDVDMHEAGLHAASLNMTASP
                     AQDIRYAFDLMPTGTADDWALIAARLARVPETLAGYRASLTASADKGVVSAIRQVRRTL
                     DQCETWSAPGSFFTELAASADEVPGVEGALRADLDAGVRAAREAYAGLAAFLREELAPK
                     AGTEDAVGADLYGLWARKFTGASLDPREAYAWGWAEFGRIEAELAEVAGQIKPGATPAE
                     AAEVLDGDPRYRVRGHAGFQAWMRDLSEQALADLRGKHFDIPDELMRLDCRIAPPGGGL
                     GAYYTNPADDFSRPGTMWWSLPADKQSFSTWREASTVYHEGVPGHHLQIGTAVATPALN
                     RFQRLLCFIDGHGEGWALYAERLMREFGYLDDGYLLGMLNKHIFRAARVIVDIGMHLKL
                     EIPAGTGFHEGRHWTPELAQEFLRTRTLTDKARAVDEIDRYLGWPAQAPSYKLGERLWL
                     SIRETLRTERGSEFDLRDFHMRALRSGPAGLDTLRQVLTKTD"
     gene            complement(18312..19802)
                     /locus_tag="IE325_RS12020"
                     /old_locus_tag="GCM10018780_24210"
     CDS             complement(18312..19802)
                     /NRPS_PKS="Domain: AMP-binding (11-398). E-value: 1.3e-79.
                     Score: 259.7. Matches aSDomain:
                     nrpspksdomains_IE325_RS12020_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01733.1"
                     /locus_tag="IE325_RS12020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_24210"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_190069777.1"
                     /sec_met_domain="AMP-binding (E-value: 5.3e-88, bitscore:
                     290.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESRLRTVVDLFEHQVRARPDALAVRTRERSWTYAEFDRATTRLA
                     HRLRHAGAGPGTVVGLLAPRGAAALTGLLAVLRCGAACLPLDPDDPPRRNREVLDDAGC
                     EQILVTAPTEWCPEALLLEDPTPVEAAVLPHPQPLDLAYAITTSGSTGRPKIVGVPHEG
                     IHNLIVASIEDLDLIRPDDVMLWTTAPTVDSTMHDVLMPLCAGACVAIGDDADLPASRI
                     LVTVRALGVTALEIPAAVLGPYGRSLLPRLARAGVRLVITGGSQLDGLGLADSPPLVVA
                     NGYGPTEASVAATWYRCNPSTPSWVPIGSPVRGVGTYVLDDDLRPVPAGDEGQLFIAGI
                     GLARGYIGLPARTAAAFLPDPFSETPGSRMYATGDRVRLQPDGDYVYLGRIDDQVKIRG
                     FRVEIGEVEHALRECAGAVDSAVLLREDTPGGAAIVAFLVGERSPDEVLTGQLRDRLPS
                     HMLPRFFVWLDNMPLNRAGKVDRKALARMPVGDPVRRT"
     CDS_motif       complement(18579..18644)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS12020_0004"
                     /evalue="5.40E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="IE325_RS12020"
                     /protein_end="408"
                     /protein_start="386"
                     /score="37.6"
                     /tool="antismash"
                     /translation="YLGRIDDQVKIRGFRVEIGEVE"
     aSDomain        complement(18609..19769)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS12020_AMP-binding.1"
                     /evalue="1.30E-79"
                     /label="IE325_RS12020_AMP-binding.1"
                     /locus_tag="IE325_RS12020"
                     /protein_end="398"
                     /protein_start="11"
                     /score="259.7"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEHQVRARPDALAVRTRERSWTYAEFDRATTRLAHRLRHAGAGPG
                     TVVGLLAPRGAAALTGLLAVLRCGAACLPLDPDDPPRRNREVLDDAGCEQILVTAPTEW
                     CPEALLLEDPTPVEAAVLPHPQPLDLAYAITTSGSTGRPKIVGVPHEGIHNLIVASIED
                     LDLIRPDDVMLWTTAPTVDSTMHDVLMPLCAGACVAIGDDADLPASRILVTVRALGVTA
                     LEIPAAVLGPYGRSLLPRLARAGVRLVITGGSQLDGLGLADSPPLVVANGYGPTEASVA
                     ATWYRCNPSTPSWVPIGSPVRGVGTYVLDDDLRPVPAGDEGQLFIAGIGLARGYIGLPA
                     RTAAAFLPDPFSETPGSRMYATGDRVRLQPDGDYVYLGRIDDQVKIR"
     CDS_motif       complement(18732..18821)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS12020_0003"
                     /evalue="2.80E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="IE325_RS12020"
                     /protein_end="357"
                     /protein_start="327"
                     /score="35.7"
                     /tool="antismash"
                     /translation="PAGDEGQLFIAGIGLARGYIGLPARTAAAF"
     CDS_motif       complement(19320..19379)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS12020_0002"
                     /evalue="6.40E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="IE325_RS12020"
                     /protein_end="161"
                     /protein_start="141"
                     /score="21.9"
                     /tool="antismash"
                     /translation="AYAITTSGSTGRPKIVGVPH"
     CDS_motif       complement(19542..19583)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS12020_0001"
                     /evalue="2.70E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="IE325_RS12020"
                     /protein_end="87"
                     /protein_start="73"
                     /score="14.3"
                     /tool="antismash"
                     /translation="LAVLRCGAACLPLD"
     gene            complement(19802..20008)
                     /locus_tag="IE325_RS12025"
                     /old_locus_tag="GCM10018780_24220"
     CDS             complement(19802..20008)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1009: mbtH-like protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016711157.1"
                     /locus_tag="IE325_RS12025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_24220"
                     /product="MbtH family protein"
                     /protein_id="WP_190069778.1"
                     /transl_table=11
                     /translation="MFDDDDREFSVVVNHEEQHSIWPADRDVPSGWRAEGFSGDRAACL
                     AHIDRVWTDLRPLSLRERSGGTA"
     gene            complement(20001..23858)
                     /locus_tag="IE325_RS12030"
                     /old_locus_tag="GCM10018780_24230"
     CDS             complement(20001..23858)
                     /NRPS_PKS="Domain: Condensation_LCL (20-308). E-value:
                     3.7e-80. Score: 261.1. Matches aSDomain:
                     nrpspksdomains_IE325_RS12030_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (472-864). E-value: 9e-93.
                     Score: 303.0. Matches aSDomain:
                     nrpspksdomains_IE325_RS12030_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (967-1033). E-value: 3.7e-13. Score:
                     41.5. Matches aSDomain: nrpspksdomains_IE325_RS12030_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="IE325_RS12030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_24230"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_190069779.1"
                     /sec_met_domain="Condensation (E-value: 7.9e-55, bitscore:
                     181.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 9.1e-100, bitscore:
                     329.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.7e-10, bitscore:
                     34.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKFEPRPTNPFPLVRGATTDFPLSAGQERLWWLHQWETSYEYHI
                     TGGWRFPDGVDQAALATALACLVRRHQILRTRFVLRADGTVAQEVADVIDVPVVWAGTD
                     WRAAVDRAVREPFDLARPPLLRVVVAELDDGYGLLMSLHHIITDRWSMDVLARDLFELY
                     EAALKQREPELPELAVQYGDYADWQRRFLDSGALQPQLERRVAALRGSERLELTPDRPR
                     STANDATGGTVVVELSEEATAAMTALAWRARATPAVVVTAALAATLSAYSGRTDVVVGA
                     IVSDRPRPELQDLIGFFINTVALRIDLSGEPLTFRSLVTRTRDAWMAADAHQDVPFESI
                     VGALHAGSEDRRNPLFDIAVNHAGDRVSLAEAPGAPTWWYPELPVTARFDLSLTTQVVD
                     GRLRASFVYRSALFDEAPTAALAATYIRLLEQGVSDPDQPLRQLPLIEEPERERLHSTN
                     DATPAPTATIVERVQEQAASHPTAPAVVGASGKLTYGQLNESANRLARHLLTLGAGPER
                     VIAVCLDKTIERYVVLLAVAKTGAAYLPLDPAHPADRLRFLLSDAGAILTVVSPGLDDH
                     LPDGVVPKLVLGSLDLSGYDAGDLERAALPDNLAYLISTSGSTGAPKSVAVSHRALSRL
                     VAGVPRHLDVGPGTTFLQCGPLTFDVAVLEWAPLAHGGRVVVTDTGTLLDGLDDVVRTH
                     AVTTLKLVSPQLDLLVERDIGTLAGLSRLVVGGDVVNPRSFAAARAGLPGCRVTASYGP
                     TECTVLATLFDGGEWEAGRVPIGYALPHTRVYLLDRDLRPVPVGMRGEIHLAGDGLARG
                     YHGRPDLTAAAFVPDPYGPPGARMYRTGDVGRYLPSGAIDFLGRADKQVKIRGFRIELS
                     EIEHVLLREPEITSAVVLRVESPTGPALAAYVVATAPVDVSTLRARLGLSLPAYMLPDH
                     VIEVPRIPLTANNKVDREALPPVAEAEPGSAQPSTGLEARVVEAWSGVLGRTVPADADF
                     FAHGGHSLLVPRATAAIRRLLGREVPLRLMMTHRTPAAYAAAILAETAPDAVPGEHRLE
                     RQVWRSLSFPGERRLDLYVPDGDPGPEPRTLIVLDGSEFVDIMRLPALLDRLIHQHRIP
                     PTAALFVSPAEWSVRNRELLDEKFVDVLADELIPYLRDRLGKGWPSGGRTTAVGASLGA
                     VTAVRAALHRPDRFDGAVGMSGPLTDHRLAQATPGDPGPARFFLSASREEADAMLDGGI
                     SQLDATKRTGEDLALRGHVVRCAYGDGGHTYAAWEAMLPEAIGWALSGGNNDQDGDVDH
                     V"
     aSDomain        complement(20760..20957)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS12030_PCP.1"
                     /evalue="3.70E-13"
                     /label="IE325_RS12030_PCP.1"
                     /locus_tag="IE325_RS12030"
                     /protein_end="1033"
                     /protein_start="967"
                     /score="41.5"
                     /tool="antismash"
                     /translation="EARVVEAWSGVLGRTVPADADFFAHGGHSLLVPRATAAIRRLLGR
                     EVPLRLMMTHRTPAAYAAAIL"
     aSModule        complement(20760..23798)
                     /complete
                     /domains="nrpspksdomains_IE325_RS12030_Condensation_LCL.1"
                     /domains="nrpspksdomains_IE325_RS12030_AMP-binding.1"
                     /domains="nrpspksdomains_IE325_RS12030_PCP.1"
                     /locus_tags="IE325_RS12030"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(21237..21302)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS12030_0009"
                     /evalue="1.30E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="IE325_RS12030"
                     /protein_end="874"
                     /protein_start="852"
                     /score="36.5"
                     /tool="antismash"
                     /translation="FLGRADKQVKIRGFRIELSEIE"
     aSDomain        complement(21267..22442)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS12030_AMP-binding.1"
                     /evalue="9.00E-93"
                     /label="IE325_RS12030_AMP-binding.1"
                     /locus_tag="IE325_RS12030"
                     /protein_end="864"
                     /protein_start="472"
                     /score="303.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="QEQAASHPTAPAVVGASGKLTYGQLNESANRLARHLLTLGAGPER
                     VIAVCLDKTIERYVVLLAVAKTGAAYLPLDPAHPADRLRFLLSDAGAILTVVSPGLDDH
                     LPDGVVPKLVLGSLDLSGYDAGDLERAALPDNLAYLISTSGSTGAPKSVAVSHRALSRL
                     VAGVPRHLDVGPGTTFLQCGPLTFDVAVLEWAPLAHGGRVVVTDTGTLLDGLDDVVRTH
                     AVTTLKLVSPQLDLLVERDIGTLAGLSRLVVGGDVVNPRSFAAARAGLPGCRVTASYGP
                     TECTVLATLFDGGEWEAGRVPIGYALPHTRVYLLDRDLRPVPVGMRGEIHLAGDGLARG
                     YHGRPDLTAAAFVPDPYGPPGARMYRTGDVGRYLPSGAIDFLGRADKQVKIR"
     CDS_motif       complement(21387..21476)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS12030_0008"
                     /evalue="4.20E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="IE325_RS12030"
                     /protein_end="824"
                     /protein_start="794"
                     /score="47.8"
                     /tool="antismash"
                     /translation="PVGMRGEIHLAGDGLARGYHGRPDLTAAAF"
     CDS_motif       complement(21972..22031)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS12030_0007"
                     /evalue="5.40E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="IE325_RS12030"
                     /protein_end="629"
                     /protein_start="609"
                     /score="22.1"
                     /tool="antismash"
                     /translation="AYLISTSGSTGAPKSVAVSH"
     CDS_motif       complement(22218..22259)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS12030_0006"
                     /evalue="1.80E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="IE325_RS12030"
                     /protein_end="547"
                     /protein_start="533"
                     /score="14.9"
                     /tool="antismash"
                     /translation="LAVAKTGAAYLPLD"
     CDS_motif       complement(22773..22880)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS12030_0005"
                     /evalue="2.50E-10"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="IE325_RS12030"
                     /protein_end="362"
                     /protein_start="326"
                     /score="32.6"
                     /tool="antismash"
                     /translation="MAADAHQDVPFESIVGALHAGSEDRRNPLFDIAVNH"
     aSDomain        complement(22935..23798)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS12030_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.70E-80"
                     /label="IE325_RS12030_Condensation_LCL.1"
                     /locus_tag="IE325_RS12030"
                     /protein_end="308"
                     /protein_start="20"
                     /score="261.1"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIITDR"
                     /tool="antismash"
                     /translation="DFPLSAGQERLWWLHQWETSYEYHITGGWRFPDGVDQAALATALA
                     CLVRRHQILRTRFVLRADGTVAQEVADVIDVPVVWAGTDWRAAVDRAVREPFDLARPPL
                     LRVVVAELDDGYGLLMSLHHIITDRWSMDVLARDLFELYEAALKQREPELPELAVQYGD
                     YADWQRRFLDSGALQPQLERRVAALRGSERLELTPDRPRSTANDATGGTVVVELSEEAT
                     AAMTALAWRARATPAVVVTAALAATLSAYSGRTDVVVGAIVSDRPRPELQDLIGFFINT
                     VALRIDL"
     CDS_motif       complement(22944..23033)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS12030_0004"
                     /evalue="3.40E-14"
                     /label="C5_LCL_267-296"
                     /locus_tag="IE325_RS12030"
                     /protein_end="305"
                     /protein_start="275"
                     /score="45.1"
                     /tool="antismash"
                     /translation="DVVVGAIVSDRPRPELQDLIGFFINTVALR"
     CDS_motif       complement(23283..23321)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS12030_0003"
                     /evalue="2.20E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="IE325_RS12030"
                     /protein_end="192"
                     /protein_start="179"
                     /score="13.9"
                     /tool="antismash"
                     /translation="QYGDYADWQRRFL"
     CDS_motif       complement(23370..23435)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS12030_0002"
                     /evalue="4.50E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="IE325_RS12030"
                     /protein_end="163"
                     /protein_start="141"
                     /score="32.0"
                     /tool="antismash"
                     /translation="LHHIITDRWSMDVLARDLFELY"
     CDS_motif       complement(23622..23732)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS12030_0001"
                     /evalue="2.60E-11"
                     /label="C2_LCL_024-062"
                     /locus_tag="IE325_RS12030"
                     /protein_end="79"
                     /protein_start="42"
                     /score="35.9"
                     /tool="antismash"
                     /translation="YHITGGWRFPDGVDQAALATALACLVRRHQILRTRFV"
     gene            complement(23920..24189)
                     /locus_tag="IE325_RS12035"
                     /old_locus_tag="GCM10018780_24240"
     CDS             complement(23920..24189)
                     /NRPS_PKS="Domain: PP-binding (11-69). E-value: 2.6e-08.
                     Score: 26.0. Matches aSDomain:
                     nrpspksdomains_IE325_RS12035_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE325_RS12035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10018780_24240"
                     /product="phosphopantetheine-binding protein"
                     /protein_id="WP_190069780.1"
                     /sec_met_domain="PP-binding (E-value: 3.8e-06, bitscore:
                     22.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSDTSTVDIVRKLIDQQLNLSGHGFELNHDDNLWDRGMTSLTC
                     LGLMLSIEDTFGIELPESALKESTFRSVDTITAAVDGALSSAQG"
     aSDomain        complement(23983..24156)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS12035_PP-binding.1"
                     /evalue="2.60E-08"
                     /label="IE325_RS12035_PP-binding.1"
                     /locus_tag="IE325_RS12035"
                     /protein_end="69"
                     /protein_start="11"
                     /score="26.0"
                     /tool="antismash"
                     /translation="VRKLIDQQLNLSGHGFELNHDDNLWDRGMTSLTCLGLMLSIEDTF
                     GIELPESALKEST"
     gene            complement(24186..25661)
                     /locus_tag="IE325_RS12040"
                     /old_locus_tag="GCM10018780_24250"
     CDS             complement(24186..25661)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013434.5"
                     /locus_tag="IE325_RS12040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_24250"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_190069781.1"
                     /sec_met_domain="DAO (E-value: 3.1e-31, bitscore: 104.4,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTETAINETPKHADVVIVGNGALGLFLADELMERGMGSVVVVGPS
                     HRETGASQAAGAMLGCFGETTTESLRTDAARTRFELGVNSHERWPAVLAKLEEYSRTGR
                     PLQSAPDTHVVLNSIGAELDTVNFKAMIDALDQYGKPWEEMDPNDIPGFNPRLDTRSLR
                     AVHLPTEGAVDARGVLTALESRLSDTGAVQVDRSVRRLLGSGDVVTGVELDDGHVIEAG
                     TVVVAAGIHSESLVRTVSEDIDLIPTFPGLGFAMIARRSGGDPFRSVVRTPNRGFACGL
                     HVVPQGDGLEYYGATNRLVDSITGVTWMADVRFLAQYSMQQLDERAAGHEVVQWLAGNR
                     PVTLDGFPMIGWLPPSGLYLMTGTYRDGFHCAPLLAEHVANELQGKPGTIDPMFAPTRE
                     PIVTRTIEWSIDEYVEHNLAAWFETGAEAAPQMTTAQIAEYYRTRCVQAYDQLGIDYAL
                     GPDILWYAQGSLLGARRIRRYLRGRQSASEVAK"
     misc_feature    complement(25452..25454)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    25754..25767
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 20.14"
                     /tool="antismash"
     misc_feature    complement(26061..26075)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.04"
                     /tool="antismash"
     gene            26095..27291
                     /locus_tag="IE325_RS12045"
                     /old_locus_tag="GCM10018780_24260"
     CDS             26095..27291
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016640032.1"
                     /locus_tag="IE325_RS12045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_24260"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_229911762.1"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 3.9e-07,
                     bitscore: 25.0, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp_3 (E-value: 2.7e-08, bitscore:
                     29.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVLRKAHDLGLDVVYIQHPDEYDSSHWPYVGQALLVDYADTERV
                     LPLVRSLHETYPFHMVVSPWELGLLPAAKIDDALGLGGNPLRTVEMLLDKSRMRAHLNA
                     SGISPVAAEVGRTERDLREFARANGLPVVVKPIDEAGSIGIFKVRDESDLASVVERFHA
                     LGKQIDKKDLAGDLDRFLMEEYLDGPEISVETLSFDGRHVLVGVTDKLCLDSGFVETGH
                     SQPSRHPAELLRDAEDLVMKFLDAIGLRHGPAHTEIKLTSRGPVIIESHNRVGGDRIHD
                     LTEIAYGVDMDRYTLGSRFGLIEPLERAPQPVAGAAIRFFTPPPGRVTEVTGAESIAAD
                     PALYDLVISVEPGDEVRPLTWSDDRVGHVIARGATAEEAIANCERLLAAVRIHTEPIT"
     gene            27288..28559
                     /locus_tag="IE325_RS12050"
                     /old_locus_tag="GCM10018780_24270"
     CDS             27288..28559
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003997736.1"
                     /locus_tag="IE325_RS12050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_24270"
                     /product="MFS transporter"
                     /protein_id="WP_229911763.1"
                     /transl_table=11
                     /translation="MSTEQPDVQDPPFRETLRELPPRVWIVSLGILVNRCGNFLPVFIV
                     LYLTSQGYSPGAAGLVLGSAGLGNVLGSALGGYLADQLGRRWTIALSGVTTAALTAVIP
                     VLDGLVMNIIVVGLVGAASQVYRPAAAALLTDSVTTNQQRVAAFAVFRFAMNLGAAAGG
                     FLGGWLAANSYTELFLGNAAACLLFGVIAVLLLRDVPHRGSEEDGEDGSEAKEQGSYKL
                     ALADRRLRRFLLMTVIAELVYIQSTVGLPLHVTASGLSEADFGLLIGLNGVLVLVCELP
                     IAGLVVKRRATHVLAWGNLATGVGLALTGFATDMIWLAATVVLWSLGEMMYSSVANAHL
                     GGLSPAGMVGRYQGLYGAAFTLGTGVGPLIGAAIYAYNEWALWAAIGVAGVISAQLCLP
                     GRRASAPPDTEGDGPRQRADEASA"
     gene            complement(28587..29954)
                     /locus_tag="IE325_RS12055"
                     /old_locus_tag="GCM10018780_24280"
     CDS             complement(28587..29954)
                     /EC_number="4.3.1.17"
                     /GO_function="GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889625.1"
                     /locus_tag="IE325_RS12055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_24280"
                     /product="L-serine ammonia-lyase"
                     /protein_id="WP_190069783.1"
                     /transl_table=11
                     /translation="MAISVFDLFSIGIGPSSSHTVGPMRAARMFAHRLRNEDVLSSVAS
                     IRSELYGSLGATGHGHGTPKAVLLGLEGASPRTVDVEGADERVEKIKSGGRLRLLDERE
                     IPFDFDKDLVLHRRKTLPYHANGMTLWAYDASGAELLSKTYYSVGGGFVVDEDAVGADR
                     IKLDDTVLKYPFRTGDELLRLTQETGLSISSLMLENERAWRTEEEIRAGLLEIWRVMRE
                     CVSRGMSREGILPGGLKVRRRAANTARKLRSEGDPKALAMEWITLYAMAVNEENAAGGR
                     VVTAPTNGAAGIIPAVLHYYINFVPGADEDGVVRFLLAAGAIGMLFKENASISGAEVGC
                     QGEVGSACSMAAGALAEVLGGSPEQVENAAEIGMEHNLGLTCDPVGGLVQIPCIERNGM
                     AAVKAVTAARMAMRGDGSHKVSLDKVIKTMKDTGADMSVKYKETARGGLAVNIIEC"
     CDS             complement(30048..>30888)
                     /EC_number="2.1.2.1"
                     /GO_function="GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0070905 - serine binding [Evidence IEA]"
                     /GO_process="GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=3
                     /gene="glyA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675119.1"
                     /locus_tag="IE325_RS12060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="serine hydroxymethyltransferase"
                     /protein_id="WP_190069784.1"
                     /transl_table=11
                     /translation="NVVAYHVDEAGLVDMAEVERLAKEHRPKVIIAGWSAYPRQLDFAE
                     FRRIADEAGAYLWVDMAHFAGLVAAGLHPNPVEYADVVTSTTHKTLGGPRGGIILAKKD
                     FAKKLNSSVFPGFQGGPLEHVIAAKAVSFKVAASDEFKERQRRTVEGARLLAERLTAAD
                     ARAAGVNVLSGGTDVHLILVDLRESELDGQQAEDRLHEVGITVNRNAVPNDPRPPMVTS
                     GLRIGTPALATRGFQAEDFAEVADVIAETLKPSYDVEALKARVRALAEKHPLYPGLNK"
     gene            complement(30048..>30892)
                     /gene="glyA"
                     /locus_tag="IE325_RS12060"
ORIGIN
        1 aggaggcggc tgtatgagcg ccgctctggt caaccccgcc gtactgagga gcgaggtccg
       61 gctcttccgt cgcgagcccg gcgccctgtt ctggatgctg gggttcccga ccctgctgct
      121 ggcgatcctc ggctcgatcc ccgccttccg ggagaccgac cccgccttcg gcgggctgcg
      181 cccggtcgac ggctacgtcc cggtggccgt gctgctcggc ctgatcgtcg gcgggatcca
      241 ggcgatgccg cagaccctca ccggctaccg ggagcgcggc atcctgcgcc ggatgtccac
      301 cacccccgtc cggccgtccg ccctgctgtc cgcacagatg ctgctgttcg gcggggccgc
      361 cctggtctcc gcgctgttcg ccctggcggt cggccggctc gccttcgacg tacggctgcc
      421 gcgccagggc ttcggctacg ccctcgccct gctcctggcc gtactggtcg ccctcgcgct
      481 gggcgccgtg atctccgcgc tgtcccggac cacgaagatc gccggtgcca tcgggtcggc
      541 cgtgttcttc ccggccatgt tctgcgcggg cgtgtggatg ccggtgcaga ccatgccgga
      601 cgtgctggcg aggatcgtcg gctacacgcc cttcggggcg gcggccgagg ccctcaacca
      661 ggcggcggcg gggcactggc cgggctgggg ccacctgggc gtgctcgtgg cctggacggt
      721 gctgctcacg gcaggggccg cacgctggtt ccgctgggag taggcggacc gccgtgcaga
      781 ctggagccat gaccgcggcg gacacggaca tcgagcggcg ctgggaactc atccgcggcg
      841 tcggtcccta cgggctgctc atggtcggca cactgctggc gctggccacc gccgaactga
      901 cgccggggcc ggcgcagcgc accaccgtcg ccgcgctggt cgtcgcgggc ctcgtcctcc
      961 aggtgtggtg gggccgggcc cgccgcaccc gccccggccc ctccaccgcc ggcaccgtgt
     1021 actacgcgct gcgctgggcg ctcggcttcg cgctgacctg gctgaatccg ttcttcgcgt
     1081 tctacgcggt caccggctac ttcgactccg acgagctgat tcccggccgg cgtctgcggt
     1141 ggctcggccc gttcgcctgc tcgatcgccg tctcgggctc gcaggccggc gggctgccct
     1201 tcaaggagcc cgtccagtgg gcggtgttcg ccgggctcct ggtggtcaac aacgtcatcc
     1261 tgaccgtggt cggccatctc accaaccagc aggaggaacg ctcccgcgcc cgggccgcca
     1321 ccatcgccga gctcgaacgc acgaatacgg cgttgcagca ggcgctcgac gagaacgccg
     1381 ccctccactc ccaactcctc gtccaggccc gggaagcggg cgtcgcggac gagcggcgcc
     1441 ggctcgccgc cgagatccac gacaccctcg cccagggtct gaccggcatc atcgcccagc
     1501 tccaggtcgt ggcgaacgcc cccgatctgc ccaccgcccg cacccacctc gaccgcgcct
     1561 ccgccctcgc ccgccacagc ctcggcgagg cccgccgctc ggtgcacaac ctcgcccccg
     1621 tggccctgga gaacgacgga ctgccccagg ccctcaagag cacggtcgcc gaatgggccg
     1681 aacgcaccgg cgtacgcgcc gacttcaccg tcaccggcac cgcggaacaa ctccacgacg
     1741 aactctccgc gaccctcctg aggatcgccc aggaagccct gtccaacgcc tcccggcacg
     1801 cccgcgcgac ccgcctcggc gtcaccctca ccttcctcgg cgaggaggtc atcctcgaca
     1861 tccgcgacga cggccagggc ttcgacccgc tcaccctccc cgagcgcggc cacaccggcg
     1921 gcttcggcct gcccggcatg cgcgcccgcg ccgagcgcat ggcgggctgc ctcaccgtcg
     1981 agtccgaacc ggggcgcggc acggccctgt cggctcgcgt accgttggtg cgccatgagt
     2041 agcgacgagt cgtccatctc cctgctgatc gtcgacgacc atcccgtcgt acgggacggt
     2101 ctgcgcggca tgttcgagtc ggcgccgggc ttcgtcgtgc tcggggaggc ggccggtggc
     2161 gaggaggccc tggagcgtgc cgccgcactc gacccggacg tgatcctgat ggacctgcgc
     2221 atgccgggcg gcggtggggt cgcggcgatc gcccacctca cccgcatcgg cgcccgcgcc
     2281 aaggtcctcg tactgaccac gtacgacacc gactccgaca ccctccccgc gatcgaggcg
     2341 ggcgcgacgg gctacctcct gaaggacgcc ccgcgcgacg aactcttcac cgccgtcagg
     2401 gcggcggccg agggccgtac cgtcctctcc ccggcggtag cctcccgcct ggtctccgcc
     2461 gtccgcaccc cgaaggccca cggcaacgag cccctctccg cccgcgaacg cgaggtcctg
     2521 gccctggtcg ccaagggcac ctccaaccgc gagatcgccc gcgagctctt catcagcgag
     2581 gcgaccgtga agacccatct cacccacctg tacgccaagt tgggcgtcaa ggaccgggcg
     2641 gcggcggtgg cgacggcgta cgagcgggga atcctcggct gatcagccgt ccacccgcag
     2701 caacagcacc gcccgccccg gcaccgtgat ccccgccccc gccggatgct ccacccccgg
     2761 tgcctcgccc tgctcctccc gcgaggtgtc gacgaccacc tcgtaccgct ccgcccaagg
     2821 cgggcccggc agtacgaagc tcaccggccg gtccccggcg tgcagcaccg ccaggaagct
     2881 gtcgtcgact atcggtgccc cgcgctcgtc gcggcccggg atgtcccgcc cggacagaaa
     2941 catgcccagc gtggcggcgg gcgcgtacca gtcccgttcc gtcatctccg ttccccgtgc
     3001 ggtgaaccag gccaggtccc gcagtccgtc cgccgagtgc gcccgcccgg agaagaaggc
     3061 ccggcgtcgc agcacgggat gccggtgccg cagctcgatg aggcgggcgg tgaggtcgaa
     3121 gagggccttc cagcccggct cctccagcag ctcccagtcc agccagctga tctcgttgtc
     3181 ctggcagtag gcgttgttgt tgccgcgctg ggtgcgcccc agctcgtcgc ccgcgaccag
     3241 catcggcacg cccgtggaga gcagcagggt ggtcagcaga ttccgtagct gccgccgcct
     3301 gagcgcccgt acgcgctcgt cgtccgtctc cccctcgacc ccgccgttcc aggcccggtt
     3361 gtcgtccgag ccgtcccggt tgccttcccc gttcgcctcg ttgtgcttgc gctcgtagga
     3421 caccaggtcg cggagcgtga aaccgtcgtg ggccgtcacg aagttgacgg aggcgtacgg
     3481 ccttcggcct ccccacgcgt acaggtcact ggaccccgag agccggtacc ccagatcccg
     3541 tacgtccggc agcgcgcccc gccagaagtc ccgtacggcg ttgcggtagc ggtcgttcca
     3601 ctccgtccac aggggcggga aggcgcccac ctgataccca ccggacccca cgtcccacgg
     3661 ctcggcgatc agcttcaccc ggcgcagcac cgggtcctgg gcgatgaccg cgaggaacgg
     3721 cgagagcatg tcgacatcgt gcatggagcg ggccagcgcc gccgccaggt cgaagcggaa
     3781 gccgtccacg cccatctccg tcacccagta gcggagggag tcggtgatga gccggaggac
     3841 atgcggctgg acgacgtgga gggtgttccc gcacccggtg tagtcggcat acctccgtgc
     3901 atccgactgc aaccggtagt acccccggtt gtcgatgccc ttcagcgaca gcgtcgggcc
     3961 cagctcgccc gcctccgccg tgtggttgta gacgacgtcg aggatgacct cgatcccggc
     4021 gtcgtgcagc gcacgcacca tccgcttgaa ctcgcccacc tgctgacccg tcgtacccga
     4081 ggcggcgtag gcggcgtgcg gggcgaaata gccgatggag ttgtagcccc agtagttgcg
     4141 caggcccttg cgcaggaggt ggtcctcgtg cgcgaactgg tggacgggga gcagctcgac
     4201 ggccgtgacg ccgagcttga cgaggtgctc gatcgcggcc ggatgcgcga gaccggcgta
     4261 cgtcccgcgc agttcctccg ggactccggg gtgcagcttg gtgaaccccc gcacatgcac
     4321 ctcgtagatc accgaatcgg cccacggcgt cttcgggcgg cggtcgtccg cccagttgtc
     4381 gtcgtcgtgc acgaccacgc ccttcgggac gtacggcgcc gagtcccggt cgtcgcgcac
     4441 ggtgtcggcg acatgctgct gcggccagtc gcggacatgg ccgtacacct cgggcggcag
     4501 gccgaagtcg ccgtccaccg cgcgcgcgta cgggtcgagc agcagcttcg ccgggttcca
     4561 gcggccgccg gtccaggggt cccagcggcc gtgcacccga tagccgtagc gctgacccgg
     4621 catcacaccg ggcacgaagc cgtgccagat ctcgtgggtc agctcggtga gccgcgcccg
     4681 tgtctccttc ccctcctcgt cgaagagaca caggtcgacg gcctccgcgc cccccgccca
     4741 cagcgcgaag ttggtgccgg ccaccccgtc cgggccgacc cggaagcggg cgccgagcgg
     4801 cacgggcgtg cccggccaca cgggcacacc gggggccttg cgccgcgcgc cgttcacgac
     4861 ggcggccggg cgcccctcct cagcggcgac cgccccggcc accgcctcct gctcggctgc
     4921 gctcgacacc tacggcctcc cacggctcac ggaccacacg atgtggaagg agagacccgc
     4981 ggtcgtccct gggccctgtc gtcagattcc cgcctgcccg gcggcgtctg gcacgcacgc
     5041 tcgccgcgtt gccgaaccgc ccacgtggct ccgccacgag ggcgctccgg cgccttgcga
     5101 tcgctcgcac cagacgccgc cgggcccgcc cttcgggcgg acgccgggaa tctgacgaca
     5161 gggcccagcc gcggctcccc gtcgcgtcgt cctcccacat gttctgccca cccgtcgggt
     5221 cgcactcacg tttcccccgg gccgccccgg tcgttggggt cttcgtgacg catctacaag
     5281 ggcgcgcgcg gcgcgcgggg gccgtgctgg ccgccgtact gacatgggcc ggtctgctgg
     5341 ccggctgcac gggtggcggc atcggcgaga tgctgggcaa ggggcaggcg tccgaggacg
     5401 tcatccgggt cacccccgac gacggttcca agggcgcacg ccccgacgac cggctgctcg
     5461 tccgggtgcc cagcgggcgg ctggagtcgg tcgaggtcgt caagtcccag gacgcccagg
     5521 acaccccggt gcccgggcgc atctccaagg acggcctgcg ctgggagccc gaggaccccc
     5581 ggctcgcgct ggccgcgaag tacacgatcg acgcggtggc cctcgacggc cacgggcgcc
     5641 gcagcgcacg gcacacgacc ttcaccacgt acgtccccga caagcggttc atcgcctacg
     5701 tcaccccgga gcaccgctcc accgtaggca ccggaatgat cgtctccctg gagttcaacc
     5761 gggagatcca gaaccgggcc gccgtcgaac gcgccgtaca ggtcaccgcc gagcccgccg
     5821 tggagatccg cccgcactgg ttcggcaagg cccgcctcga cttccgtccc cgcgactact
     5881 ggaagcccgg caccaaggtc accgtctcgc tgcggctgcg ggacgtccag ggggcgcccg
     5941 gggcctacgg cctccagcac aggaccttct ccttcaccgt cggccgccac caggtctccc
     6001 tggtcgacgc cgccgagcac accatggagg tccgccgcga cgacgaactg ctcgcctccg
     6061 tccccatcac ggccggcgcc ccgaagatga ccacctacaa cggcaagatg gtagtcaccg
     6121 agatgctcga actcacccgg atgaacggcg ccacggtcgg cttcaagaag aagaacggca
     6181 agggcgagta cgacatcccc gacgtcccgc acgccatgcg cctgaccgac tccggcacct
     6241 tcctgcacgg caactactgg gcggaccgct ccatcttcgg gcagagcaat gtcagccacg
     6301 gctgcgtcgg cctcagggac gtcaagggcg gcggctccga cacacccgcg ggctggttct
     6361 tcgaccgcag cctggtcggg gacgtcgtcg aggtcgtccg cagcaatgac aaaaaggtcg
     6421 ctcctgacaa tggcctcgga ggatggaata tgggttggaa ggagtggaag gcggggagtg
     6481 cggtgaagta atccgacagg ggggtgagtt gcccggcggc aggccggctg tcgatgttgg
     6541 aacggaacag tgacaaacgc gcggcgccga cgcgtccggc catgtggtta atatgcgccg
     6601 atgcgcgcgg ctgacgcgcg ggggtgcggg cctgacctgg cccggggagg ggagaaagac
     6661 ttgaacgtgc ggccgatatc gggggcgtcg gttgacggac gcaggcgggt cgggctggcc
     6721 gcggtcgccg gggcgctgct gctgaccgtc accgcgtgcg gcgggggcgg cggatcggac
     6781 tcgggtgccg ggggcggcaa gggcggggac gccggcgccg ctcaggccaa gaagtcgcag
     6841 gcggtcgtga ccatagcgcc gggcgacggc gccaagtccg tcgacaccag cggcgccctg
     6901 aaggtgaccg cggccaaggg caagctcacg gacgtcgagg tcaaggacgc caagggcaac
     6961 gcgatagacg ggaagatatc cggcgacggc ggcacctgga ctccgtccac gcatctcgcc
     7021 gccgccacca agtacacggt gcacgcggtc gccaaggaca ccgacggcct ggaggccgcc
     7081 aaggaggccg acttcaccac cctgacgccg aagaacacct tcatcgggcg cttcacaccc
     7141 gaggacggtt cgaaggtcgg cgtcggaatg ccgttctcgc tccgcttcga ccggggcatc
     7201 accaaccccg aggacgtcga gaaggcgatc agtatcaaga ccgagccggc cgtcgaggtc
     7261 gcgggccact ggttcggcaa cgaccgcctc gacttccggc ccgagaagta ctggaagtcc
     7321 ggcaccaagg tcaccgtcga gctcaacctc gacggcgtcg agggccgtga cggcgtctac
     7381 ggcgagcagg acaagaaggt caccttcacg atcggccgca accaggtctc ggtcgtcgac
     7441 gtgaagacca ggaagatgaa ggtcactcag gacggcaagg tcgtcaagac catcccggtc
     7501 accaccggca agcccgggta cgacacctgg aacggccaga tggtgatgac cgagaagttc
     7561 gtcgagaccc ggatgaacgg cgacacggtc ggctacgacg gcgagtacga catcaaggac
     7621 gtcccgcacg ccacccgcct gaccgactcc ggcaccttca tccacggcaa ctactggggc
     7681 ggcggcgcct tcggcaacta caacgccagc cacggctgca tcggcctgcg cgacgtcaag
     7741 ggcgcctggg acaagggcac cccggccgcg tggttcttcg accactcgat ggtcggtgac
     7801 gtggtggtcg tgaagaactc cgccgacgcg acggtcgacc cggggaacgg gctcaacggc
     7861 tggaacatgt cgtgggagaa gtggaaggca tagctcccat gtgacgtgcg tacggccccg
     7921 gtgtgaggta cggcaccggg gccgctcccg ttagtccccg ttaacctgct cgcatgaccg
     7981 tgaatctcga agtcgccgaa ggtgtcggta ccctccgtct cgaccgcccg cccatgaacg
     8041 cgctggacgt cgccacccag gaccggctca aggagctcgc cgaggaggcg acccggcgtg
     8101 acgacgtacg ggccgtggtg atctacggcg gggagaaggt gttcgcggcg ggcgcggaca
     8161 tcaaggagat gcaggccatg gaccacacgg cgatggtcct gcgtgcccgg gccctgcagg
     8221 agtcgttcac ggcggtggcc cggatcccca agccggtggt ggcggcggtg accggctacg
     8281 cgctcggcgg cggctgcgag ctggcgctgt gcgcggactt ccggatcgcc ggggagaacg
     8341 ccaagctggg ccagcccgag atcctgctcg gcctgatccc gggcgccggc ggtacccagc
     8401 gcctcgcccg gctgatcggc ccgtcgaagg cgaaggacct gatcttcacg ggccgtatgg
     8461 tgaaggcgga ggaggcgcgg gaactcggcc tggtggaccg ggtcgtggcg ccggatcagg
     8521 tctacgcgga ggcgcacgcc tgggccgcca ggctggcgca gggcccggcg atcgcgctgc
     8581 gcgccgcgaa ggagtcgatc gacaccggcc tggagacgga catcgagacg ggcctcgcgg
     8641 tggaacgcgg ctggttcgcg gggctgttcg cgacggagga ccgggagcgg ggcatgcgga
     8701 gcttcgtgga ggagggtccg ggcaaggcga agttcctcta gaggcggacc gaaacgcggc
     8761 cgtatcactt gcaattgacg gcgtgtctga tccgggtccc tcgatggggc ggtttatggg
     8821 agccttaagg caaccttaag cgtgccttgt cgagggagcc tgtcgattgc ctccagcgga
     8881 cccttcgtcg caggtcggac gggctgtgcg aggccctgaa ctgccgctgt catatgccaa
     8941 ccgggccgtt cggaatgagc gcttccgggg ggtgtattcc tccggaacgg cccccaaggg
     9001 ccccgcggac ggccatgatg ggggcatggc ggggctggag ggtgtcgaac acccgcgggg
     9061 aaacggccgt gcgactgcgg cacgctggtc gccggcggtc gaggacgaag ccgcatcaaa
     9121 ggcgctggag ctgttcggca atcccacgga ggccgaggtt ccgctcccgt cccgccccga
     9181 gtccgcggcg accgcgcgca gactggccca ggtggtcgtc ctgcgccagt ggggactcac
     9241 cccgaagatg acggaggacg cggtcctgct cgtctcggaa ctggtcggca acgccgtccg
     9301 ccacaccggc gcccgtgtct tcggcctccg tatgcggcgc cgtcgcggct ggatccgtat
     9361 cgaggtccgt gatccctccc gcggtctgcc ctgtctcatg ccggtccagg agatggacat
     9421 cagcggccgg gggctgatgc tcgtcgacaa gctcgccgac cggtggggcg tggatctgct
     9481 gccgcgcggc aagacgacgt ggttcgagat gagggtggcg gagcgttagt ccgtcggtgc
     9541 cgcctatcgg gtcaatcgca cgattttctg cgtaatccac attaaatggt ccggtgatct
     9601 ttggtgaccg tcgcgccgcc accccgccgt accggaagaa ctgccgatga atcgcaccca
     9661 ccgcaccctc ctcgcagccc tgggcctcct cgcgctggcc gcctgcggca ccgagtccgc
     9721 caaggacacg gagcgtccca cccaggccgc catccccgct ccggtgaagg agcgggccgt
     9781 ccagggactg cccggcatgc cccccgtcct cgatccgaag gacgtctacg ccgccgaccg
     9841 cccgaacctg ctctccccgg tcgtcaagga cttcccgtcc cgcgtctacg tccccaacag
     9901 cgactccgac accgtctccg tcatcgaccc caagacctac gaggtcgtcg agaccatccc
     9961 cgtcggccgc cagccccagc acgtcgtgcc gtcctgggat ctgaagaccc tgtgggtcaa
    10021 caacaaccgc ggccacaccc tcacccccat cgacccgaag accggcaagg cgggcgagga
    10081 ggtcgaggtc cacgacccct acaacctcta cttcaccccc aacggcaaat acgccatcgt
    10141 catggcctcc ctcgaccgcg agctcgtctt ccgtgacccg cacaccatga agcggctcaa
    10201 gaccgaaccg gtcacctgct acggcgtcaa ccacgccgac ttctccctcg acggccgcta
    10261 cttcatcgtc tcctgcgagt tcagcggcga actgctgaag gtcgacacgg agaagatgaa
    10321 ggtcgtcggg cagcagaaac tccccttcga cggcgcgatg ccgcaggacg tcaaggtctc
    10381 ccctgacggc aagaagttct acgtcgccga catgatggcc gacggcatgt gggtcctgga
    10441 cggcgacaag ttcagcgccc cgaagctcct gcccaccggc aagggctgcc acggcctcta
    10501 cgtcagccgc gactcccgcg agatgtatgt ctccaaccgc ggcgagggca ccgtctccgt
    10561 ctacgacttc acccgcgacg aactcaccaa gaagtggcac ctccccgaag gcggcagccc
    10621 cgacatgggc ggcgtctccg ccgacggcaa ggtgctgtgg ctgtcgggac gctacgactc
    10681 ggaggtgtac gccatcgaca cccgcaccgg cgacgaactc gcccgtatcg acgtgggcga
    10741 gggcccgcac ggcctcgccg tgtacccgca gcccggccgt tactccctcg gccacaccgg
    10801 cgtcttccgc tgacatccct cgccggtgga cacgccgccg aacgggtgaa aacgggtgaa
    10861 cctgcccgac ccgcccccgc aggaccggga tcgtgatccc catgatcaca actcgcctgc
    10921 ggcggcgggc cgctgccgcc gtcctgtccc tctcggccgt cctcgccacc accgcggcca
    10981 ccgctcccga gtccgtcacc tccgcccgtc cgaccgccgc cagggccgtc cccgacccgg
    11041 ccgcctgtcc cgtccagttc gacgacccga tcgaggccgc cgccgatcgc cgcgtcgacg
    11101 tcgaccgcat cacccccgac ccggcctggc gcaccagctg cggcaccctc taccgggccg
    11161 acggccgcgg cccggagatc gtcttccggg acggcttcct gcccaaggac gtcgtcaacg
    11221 gccagtacga cgtggagaag tacgtcctgg tcaaccagcc ctccccgtac gtgtccacga
    11281 cgtacgacca cgacctgtac aagaactggt ggaaatcggg ctggaactac tacatcgacg
    11341 cccccggcgg cgtcgacgtc aacaagacca tcggcgacac ccacaaatgg gccgaccagt
    11401 tcgaggtcgc cttccccggc ggcatcgacc ggaagtacat cctcggcgtc tgcccggtgg
    11461 acaaggcgac caagaccgag atcatgagcg actgccagag caacccgcac ttcgagccct
    11521 ggcactgagc agcagcgcct ccgcgcccac cgcgcggtag cccgccgcct ggaacgcccg
    11581 catgctgcgg gcgttccccg gcgtgacctg cgcccacagc ggctccgtga ccagatgccg
    11641 ggcggcggtc accagggacc ggccgagccc ccggtgccgt accgcctcgt ccacctccac
    11701 cgacacctcc agccgcccgc cgatcccgcg ccccgtcacg accaccccgc cctccgcggt
    11761 ccacgcacgc accccgtcgc gccggccgcg ggcgtaggtg atgcgggggt ggtcggcgtc
    11821 ctcgatctcg gtgagcgcga ggggcggctc gccgggcagc gggtcggcga ccagcatcgc
    11881 gtcgatcgtc tcgacggtac ggcccgtccg gtccagcagc gccgacagga accgcgggtt
    11941 catcgtcgcc gccagccggt cgcagtccag ggagtccagc gtgtcgtaca cccagcgcgg
    12001 gtcctcgtcc acgaagacga ccgagtgcgc ggtgaaggac aggacaccgg cgtcccgccg
    12061 gcacaactgc ggcacgaccg tcgtaccgcc gtccgccggt gggaagacac cccgccccgc
    12121 cgcgtcgaga atctctccca gagtcgccat cgccccactc cccgagtcgc caccccaccg
    12181 gcccgacgag ggcgtccctg tgctggcggc tcgggtgggc ggttaatctg acctccgtca
    12241 gcaggacacc aaggtatgac atcaagtacg acgaaaaggg gcggatcggt ggcgcagatc
    12301 gacatcgagg aagcacgcag gcagttcgag cgcatcgatg cggacgggga cggaagcatc
    12361 accgccgccg agttcaagac cgccctggcc cagggcggcg actggaacgt gaccgaggcc
    12421 gtcgccgagg ccatcatcaa gagccgcgac ctcaacggcg acaagctcct gtcgttcgac
    12481 gagttctggg cctacctgag caagtgacgc ccttcgaagg ggcgcccctc cggtgcggag
    12541 gggcgcccct tcgtcatgcc cgtacgttcc agcgtccgtc ccgccgctca agggccagcg
    12601 gcaggtcgaa gcacttgccg acctggtcgc cggtgaggac ctcggccacc gggccctgcg
    12661 cgagcgcccg gccctcgcgc agcagcaggg cgtgcgaggt gcccggcgga agctcctcca
    12721 ggtggtgggt gaccaggacc gtcgccagct ccggatgacg cagccgcagt tcggtcagcg
    12781 cgccgatcag ctgctcgcgg ccggggaggt cgaggccggt ggccggttcg tcgaggagca
    12841 gcagccgggg ccggggcatc agggcccgcg cgatgagggt ccgggcgcgc tggccctgcg
    12901 acagggtggg ccagcgggcg tcgcggtgcg gccgtagccc cagtgtctcg atgagccggt
    12961 cggcccgctc ccgctgcgcc ggcgtcggcc gatgccgggg cagcggcgcc accgagttgg
    13021 tcagcccggt caggacgacg tcccgcaccc gcagcggcgc cgtcagtgga tgacgcgggt
    13081 cgacatgacc gacgtacgcg cgcagctccc gcagatcgac ccggccaagg cggcgcccca
    13141 gcacctcgac cgtgccccgg gtgggatgga tccgggcgcc cagcagggcg agcagcgtgg
    13201 acttgcccgc cccgttggcg ccgagcagcg cccagtgctc gcccgcgcgg acggtgacgg
    13261 agacgtcccg caggatcggc gtgccgtcgc gtacgacatg gacgtcctgg gcgcgcagca
    13321 ccgtcatcgc acggcccggt tcacggcgga cacgaccgcc tggacggagg ccgccgggcc
    13381 ctggccggcg ccccaggccg tgacgccgtc gacccggcac tcgacgtagg ccgcgatccc
    13441 gtctcccagc ggatgctcgg cgtagtcgat gacagcgacg gcgaacccgg caccgccgag
    13501 cgcgtccacg aacgcggaca gcgggccgct gccggtgccc tcgtggtcac cggtgcggtc
    13561 cccgatgcgc agggtgcaga cgaaccgatg ctcaccgcgg gagttgtcct gctgcacgga
    13621 ccacgcgtcc agggagattt ccccgtcgtc gatgacgtag gtggcccgga acaggtcccc
    13681 cagttccttt ggcgtgatct cccgtccgct gtcgtccgtg gccgtctgga cgacggtgga
    13741 gaagtcggcc cgcatgcgcg ccggcaggtc caggccgtgg tgggtgcgca gcagatacgc
    13801 cgtaccgccc ttccccgact gcgagttgac gcggatcacc gcctcgtagg agcgcccgat
    13861 gtcggccggg tcgatcggca gatacggcac ctcccaggcc gcctgccccg gcggaacccc
    13921 caactccgtc gccctgtacg cgtgatgggc gagccccttg ctgatcgcgt cctggtgggt
    13981 gccggagaac gccgtgtgga cgaggtcgcc ggcgtacggg tggcgggggt gcaccggcag
    14041 gcggttgcag tcctcgacga ccgccctgac cgcgtcgatg tcgccgaagt cgagcatggg
    14101 gtcgacgcct tgggcgtaca ggttcatcgc cagggtcacc agatcgacgt tccccgtgcg
    14161 ctcgccgttg ccgaacagac agccctcgac gcgctgggcg cccgccagca cggcgagttc
    14221 ggcacaggcg acgccggtgc cgcggtcgtt gtgcggatgg acggagagga tcaccgagtc
    14281 gcggcgggcg aggtgacggt ggatgtactc gatctggtcg gcgtagacgt tgggggtcgc
    14341 gatctcgacg gtcgcgggaa ggttgtgggt gacggggcgg tcggggctcg cgtcccacag
    14401 ctcactgagc ccgtcgcaga gttcgaggac gaaatccggt tcggtgagat tgaacgtctc
    14461 gggagagaac tggaaccgga ccccgtcccc cgcctgccgc gccatccgct cggccgcctc
    14521 gcgcaccgtc cgccacaccg caccgcggtc ccggccgagg acgacgtccc gccacaccgg
    14581 cgacgtcgcg atgtacagat gcacgaccgc ccgcggcagc ccggcgatgg cctcgaaggt
    14641 ccggtcgatc aggtccggcc gggccggggt gaacacgacg ggcgtgacat cgtccggtac
    14701 ggcgcccgcc accagatgcc gtacgaagtc gaactcggtg cggctcgcgg agggatagcc
    14761 cacctcgatc tccttgaagc cggtcgccac cagcagctcg aagaagcgcc gcttgcgcgg
    14821 ggtgtccatc ggctcggcga gcgcctggtt gccgtcgcgc aggtcgaccg ggacccagag
    14881 gggggcgcgc tcgatacggg ccgagggcca ggtccggtcc tcggcgggga cgtgcacacg
    14941 ctcgtggaag gggcggtagc ggtgttgggg catggggctg gggcgctgcg gattccacag
    15001 ctcggacggg ttggtggtca tcgtctgctg ctggccttcg gctcggtcgg gtcggaggac
    15061 gaccggcagc acggcgcccc gcggcggggc gccggtcgtg tcaggccccg ccgcggcagc
    15121 cgagaagaag gagaccgcag agcgtcatga tcggtacgct actcactcct cagctcctca
    15181 gacaagtaaa atgctgtcaa ctcctcagac aagtaggtga agtccgtgcc gccgtcgccg
    15241 ctcggtgccc tccggcccag ccccctggtc gaacaggccg ccgagcggct gcgcgagcag
    15301 atcgcgggcg gccactggcc cgtcggcacc aagctgcccg gcgagacgac cctggccagg
    15361 gaactcggcg tcggccgctc caccgtccgc gaggccctgc gcgccctggc cggcgccggc
    15421 ctcgtccaac cccgccaggg cgccggcgtc ttcgtcctcg ccaccgaacc ggccgaggac
    15481 tggcccaccc gcctgcgccg agccgcggtg aacgacgtct acgaggtccg catggccgta
    15541 gaggtccacg cggcccgcct cgccgcccga cgccgcaccc ccgaggacgt cacggcgatg
    15601 gaagcggcac tggaagcccg ccgagccgcc tccacggccg acgacgcgac cttcgtggag
    15661 gccgacatca ccttccacgc gacggtggtc gccgccgccc acaaccccgt actcaccgac
    15721 ctgttcaccg agttcacgcc cgtcttgcgc aagggcctgg tcgaactcct caacctgacc
    15781 ggcgtacggg ttcacgaccc caacacggca gatggcgccc atgaggcgct ggtgcgggcg
    15841 gttgtggcgg gggatgggga gggggcggcg gaggtgttgc ggggcgagtt gcaggagccg
    15901 ttcggggcca tgatgggcga ttaggccgtc atgcgttctc ggcccattca cgcaatgcgg
    15961 ccttgctgga gaaattcgcc acgttcttgt ccagcggatt gtccgtgtac tgatggaagc
    16021 gccatttcgc ctggatgcgc ggcttgcccg ccgtcacgta gtcggcgatc cagaggccgt
    16081 cgccggcgta ggacgtggtg tcgacgttga gccagtaatt cctgttcgcg tacaagatca
    16141 ccgggttgtt cggccgcttc tccttcagtt tccggatgaa cagatccttc tccgcattgc
    16201 tcgcatgcgt cccctcactc gtcgtctccc agtccacggc gagaatgtcg cccgctttct
    16261 cgggggcctt gctgacgaaa tagtcggcct gggcggagag gttgcccggc cagaggaagt
    16321 ggtagaagcc gacgaccagg ccggcgtccc gggcgcgttt tgtctgggcg gcgagtttgg
    16381 gattgatgta ggaacggccc tccgtcgcct tgatgaagac gaaggagagg ccgtcggtgg
    16441 cgtaggacga ggactggtac gcgctgacat cgatgccgcg gatcatgggg gactccctga
    16501 agtgcatgtg gggtgacagg agttggactt gttgtatgcc ccatcagggt gccgctgatc
    16561 cgtctcgcgg gtggagaggt gaggtggaga tgtgaggtgg agttatcggg gaggagtcag
    16621 tccgtcttgg tcaggacctg ccgcagtgtg tccaggcccg ccgggccgct ccgcagtgcg
    16681 cgcatatgga agtccctgag gtcgaattcg ctgccgcgct ccgtccggag cgtctcgcgg
    16741 atggacagcc acagccgctc gccgagcttg tacgagggtg cctgggccgg ccagccgagg
    16801 tagcggtcta tctcgtcgac agcgcgtgcc ttgtcggtga gggtccttgt ccgcaggaac
    16861 tcctgggcga gttcaggggt ccagtgcctg ccctcgtgga agccggtgcc tgccgggatc
    16921 tccagtttca ggtgcatgcc gatgtccacg atcacccgcg ccgcgcggaa gatgtgtttg
    16981 ttgagcatgc cgagcagata gccgtcgtcg aggtacccga actcccgcat caggcgctcg
    17041 gcgtagaggg cccagccctc gccgtggccg tcgatgaagc agagcaggcg ctggaagcgg
    17101 ttgagggccg gggtcgccac cgctgtgccg atctggaggt gatggcccgg cacgccctcg
    17161 tggtagacgg tgctggcctc gcgccatgtc gagaaggatt gtttgtccgc cgggagcgac
    17221 caccacatcg tgccggggcg gctgaagtcg tcggcggggt tggtgtagta ggcgccgagt
    17281 ccgccgcccg gcggggcgat ccggcagtcc agccgcatca gttcgtccgg gatgtcgaag
    17341 tgctttccgc gcaggtcggc gagtgcctgc tcggagaggt cccgcatcca cgcctggaat
    17401 ccggcatggc cgcggacgcg gtaccgggga tcgccgtcga gcacctcggc cgcctcggcc
    17461 ggagtcgccc cgggtttgat ctgtcccgcg acctcggcca gctccgcctc gatccggccg
    17521 aactccgccc agccccaggc gtatgcctcg cgcggatcca ggctcgcccc ggtgaacttg
    17581 cgtgcccaca ggccgtagag gtccgcgccg accgcgtcct cggtgccggc cttcggcgcg
    17641 agttcctcac ggaggaaggc ggccagcccg gcgtatgcct ccctggccgc gcgcacgccg
    17701 gcgtcgaggt cggcccgcag tgcgccttcg acgcccggca cctcgtcggc ggacgcggcg
    17761 agttcggtga agaaggatcc gggggcggac caggtctcgc actggtccag cgtccgccgc
    17821 acctgacgta tcgccgagac gactcccttg tccgccgatg ccgtcagcga cgcccggtat
    17881 cccgcgagcg tctccggtac ccgggccagc cgcgccgcga tcagcgccca gtcgtcggcg
    17941 gtcccggtcg gcatcaggtc gaaggcgtag cggatgtcct gcgccgggct cgcggtcatg
    18001 ttgagtgacg cggcgtgcag gccggcctcg tgcatgtcga cgtcgaccgt gagccgttcg
    18061 gtgaagaccg ccttggcgat gcgctcggca tcgtcgccgg gtcgcgtggc cgccatgtcg
    18121 gacagggcgg tcctggcgag ttcggcgcgt gccgcgtggc cgtcggggga gaggtcgggc
    18181 agatgggcgt catggccgcg gatgccgaac tcggtggccg cgagcggatt cagacgggcg
    18241 tagtcatcga cataggcgtc gcacacaccg tgcacgccgg cttctgcacg tggcaccact
    18301 ggactccttc ttcaggtacg tcggaccggg tccccgaccg gcatcctggc cagcgccttg
    18361 cggtcgacct tgcccgcccg gttgaggggc atgttgtcca gccatacgaa gaaacgggga
    18421 agcatatggc tcggcaaccg gtctcgcagc tggccggtga gcacctcgtc gggcgaccgt
    18481 tcgccgacca ggaaggcgac gatggcggca ccgccgggcg tgtcctcgcg tagcagcacc
    18541 gcggagtcga cggctccggc gcactcgcgc agggcgtgct cgacctcgcc gatctcgacg
    18601 cggaagccgc ggatcttgac ctggtcgtcg atgcggccga ggtagacgta gtcgccgtcg
    18661 ggttgcagcc gtacgcggtc gccggtggcg tacatccgcg atccgggtgt ctccgagaag
    18721 gggtccggca ggaacgccgc cgccgtgcgg gccggcaggc cgatgtaacc ccttgccagg
    18781 ccgatgcccg cgatgaacaa ctggccctcg tcgccggccg ggacggggcg caggtcgtcg
    18841 tccagtacgt atgtccccac ccctcggacc gggctgccga tcggtaccca gctcggggtc
    18901 gaggggttgc agcggtacca ggtggcggcg accgaggcct cggtcggacc gtagccgttg
    18961 gcgacgacca ggggcgggga gtcggcgagg ccgaggccgt cgagctggga gccgccggtg
    19021 atgacgaggc ggacgcccgc gcgggcgagt cgggggagga gtgagcggcc gtaaggtccg
    19081 aggacggcgg ccgggatctc cagcgcggtc acaccgaggg cgcgcacggt gaccaggatc
    19141 cggctcgcgg gcaggtccgc gtcgtcgccg atcgccacgc aggcgcccgc gcacagcggc
    19201 atcagaacgt cgtgcatcgt gctgtcgacg gtcggtgcgg tcgtccacag catgacgtcg
    19261 tccggcctga tcaggtcgag gtcctcgatc gaggcgacga tcagattgtg gatcccctcg
    19321 tgcggtacgc cgacgatctt ggggcgtccg gtggagccgg aggtggtgat cgcgtacgcc
    19381 aggtcgagcg gctgtgggtg gggaagtacg gcggcttcca ccggggtcgg gtcctccagc
    19441 agcagtgcct cggggcacca ctccgtgggt gcggtgacga ggatctgttc gcatcccgcg
    19501 tcgtccagca cctcccggtt gcgccggggc gggtcgtccg ggtcgagcgg cagacacgca
    19561 gcgccgcagc gcagtacggc gaggaggccg gtcagggccg ctgcgccgcg gggggccagc
    19621 aggcccacca ccgttccggg tcccgctccc gcgtggcgca ggcggtgggc cagccgggtc
    19681 gtcgcgcggt cgaactcggc gtacgtccac gaccgttccc gcgtccggac ggcgagggcg
    19741 tccggacgtg cccggacctg gtgctcgaac aggtcgacca ccgtacgcag cctggattcc
    19801 actatgccgt ccccccgctc cgctcacgca ggctcagcgg ccgcaggtcc gtccacacac
    19861 ggtcgatatg ggcgaggcac gccgccctgt cgccgctgaa tccctcggca cgccagccgg
    19921 acgggacgtc acggtcggcc ggccagatcg agtgctgctc ctcgtggttg accaccacgc
    19981 tgaactcgcg gtcgtcgtcg tcaaacatgg tccacgtccc cgtcctggtc gttgtttccg
    20041 ccgctcagcg cccagccgat cgcctcaggg agcatcgcct cccacgcggc gtaggtgtgg
    20101 ccgccgtcgc cgtacgcgca ccgcacgaca tggccgcgca gcgccaggtc ctccccggtg
    20161 cgcttggtgg cgtccaactg gctgatgcca ccgtcgagca tcgcgtccgc ttcctcgcgg
    20221 ctcgcggaca ggaagaaccg ggccgggccc gggtccccgg gagtcgcctg tgccaggcgg
    20281 tggtcggtca gcgggccgga catgcccacg gctccgtcga agcggtcggg gcggtgcagt
    20341 gcggcgcgca ccgcggtgac ggcgccgagg ctcgcgccga cggctgtcgt acgtccccca
    20401 cttggccatc ccttgcccaa ccggtccctc agatacggga tcagttcgtc ggcgagcacg
    20461 tccacgaact tctcgtccag cagctccctg ttgcggaccg accactcggc cgggctcacg
    20521 aacagggccg ccgtcggcgg gatccggtgc tgatggatca gacggtcgag cagcgccggc
    20581 agccgcatga tgtccacgaa ctcggagccg tcgagcacga tcagggttcg cggctccggg
    20641 cccgggtccc cgtcggggac gtacaggtcg agtcggcgtt caccggggaa actcaggctg
    20701 cgccacacct gtcgctcaag gcggtgctcg cccgggaccg cgtccggcgc ggtctccgcc
    20761 aggatcgcgg ccgcgtacgc ggcgggtgtg cggtgggtca tcatcagccg caacgggacc
    20821 tcgcggccga gcagtcgccg gatcgccgcg gtcgccctcg ggacgaggag ggagtggccg
    20881 ccgtgcgcga agaagtccgc gtcggcgggc accgtccggc ccagtacccc ggaccacgcc
    20941 tcgaccacac gggcctccag cccggtcgac ggctgggcgg agcccggttc ggcctcggcg
    21001 acgggaggca gcgcctcgcg atcgaccttg ttgttggcgg tcaacgggat gcggggcacc
    21061 tcgatgacat ggtcggggag catgtacgcg ggcaagctca agcccagccg ggcgcgaagc
    21121 gtggacacgt ccaccggggc cgtcgccacg acgtaggcgg ccagcgccgg ccccgtcggc
    21181 gactcgaccc gcagtacgac ggccgacgtg atctccggct cgcgcagcaa cacatgctcg
    21241 atctcgctca gttcgatccg gaagccgcgg atcttcacct gcttgtcggc gcggccgagg
    21301 aagtcgatcg ccccgctcgg cagataccgg ccgacgtcac cggtgcgata catccgggcg
    21361 ccgggcgggc cgtacgggtc ggggacgaac gccgcggcgg tcaggtccgg gcggccgtgg
    21421 tagccgcggg ccagaccgtc gcccgccagg tggatctcgc cgcgcatacc gaccgggacg
    21481 gggcgcaggt cgcggtcgag gaggtagacg cgggtgtggg gaagggcgta cccgatgggc
    21541 acccggcccg cctcccactc gcccccgtcg aacagggtcg ccagcactgt gcattcggtc
    21601 ggcccgtagg acgccgtgac acggcaaccg gggaggcccg cacgggcggc ggcgaagctg
    21661 cgtgggttga ccacgtcgcc cccgacgacg agtcggctca ggcccgcgag cgtcccgatg
    21721 tcccgttcca ccagcaggtc cagctgcggg gagaccagtt tgagggtggt gacggcgtgg
    21781 gtgcggacga cgtcgtccag gccgtcgagg agggtgccgg tgtcggtgac caccacgcgg
    21841 ccgccgtgcg cgagaggggc ccactccagc accgcgacgt cgaacgtcag gggcccgcac
    21901 tgcaggaagg tcgtcccggg cccgacgtcg agatggcgcg gcacccccgc caccagcctg
    21961 ctcagcgccc ggtgcgagac cgccaccgac ttgggtgccc cggtcgagcc ggacgtcgag
    22021 atgagatacg ccaggttgtc ggggagggcg gcccgctcca ggtccccggc gtcgtagccg
    22081 ctcagatcga gtgatccgag gaccagcttc ggcacgacac catcgggcag gtggtcgtcc
    22141 aggccggggc tgacgaccgt gaggatcgcg cccgcgtccg agagcaggaa gcgcagtcgg
    22201 tcggccgggt gggccgggtc gagcgggagg taggcggcac cggtcttggc gacggcgagc
    22261 aggacgacgt aacgctcgat cgtcttgtcc aggcagacgg cgatcacccg ctcgggcccg
    22321 gcgccgagcg tgagcaggtg cctggccagt cggttcgcgg actcgttgag ctgcccatac
    22381 gtcagcttcc cgctcgcgcc gaccacggcg ggtgccgtgg ggtggctcgc cgcctgttcc
    22441 tggacgcgtt ccacgatcgt cgccgtcgga gcgggggtcg cgtcgttggt gctgtgcagt
    22501 cgttcgcgtt cgggctcctc gatcaggggc agttgacgca acggctggtc ggggtcgctc
    22561 acgccctgtt ccagcagccg gatgtaggtg gcggccagtg cggcagtggg cgcctcgtcg
    22621 aacagcgccg accggtagac gaaggaggcg cgcagccgcc cgtcgacgac ctgggtggtg
    22681 agggacaggt cgaagcgtgc cgtcaccggc agttcggggt accaccaggt cggcgctccc
    22741 ggcgcctcgg cgaggctcac ccggtcgccc gcgtggttca ccgcgatgtc gaagagcggg
    22801 ttgcgccggt cctcggaacc ggcgtggagc gcaccgacga tgctttcgaa gggcacgtcc
    22861 tggtgcgcgt ccgccgccat ccaggcgtcc cgtgtgcggg tcacgaggga gcggaaggtc
    22921 agcggctcac cggacaggtc gatccgcagc gccacggtgt tgatgaagaa gccgatcagg
    22981 tcctgcagtt ccgggcgcgg ccggtcggag acgatcgcgc cgacgacgac atcggtccgg
    23041 ccgctgtacg cgctcagggt cgcggccagt gccgccgtca ccacgacggc cggggtcgcc
    23101 cgggcgcgcc aggccagcgc ggtcatcgcc gcggtggcct cctccgacag ttcgacgacg
    23161 acggtgccgc cggtcgcgtc gttcgccgtg gaccgggggc ggtccggcgt gagttccagg
    23221 cgttcgctcc cgcgcagcgc cgccacccgg cgctccagtt gcggctggag cgcgccgctg
    23281 tcgaggaagc ggcgctgcca gtccgcgtag tcgccgtatt gcacggcgag ttccggaagc
    23341 tccggctcgc gttgcttcag cgcggcttcg tacagctcga agaggtccct ggccaatacg
    23401 tccatggacc agcggtccgt gatgatgtgg tgcagggaca tcaacaggcc gtatccgtcg
    23461 tccagttcgg cgacgacgac ccggagcagg ggtggccggg cgagatcgaa gggttctcgg
    23521 accgcccggt ccaccgctgc ccgccagtcg gtccccgccc atacgacggg gacgtcgatc
    23581 acgtcggcga cctcctgtgc gaccgtgccg tccgcgcgca ggacgaacct ggtccgcagg
    23641 atctggtgcc tgcggaccag gcaggccaac gcggtggcca gggccgcctg gtccaccccg
    23701 tccgggaacc gccaaccgcc ggtgatgtgg tactcgtacg acgtttccca ctggtgcagc
    23761 caccacaggc gttcctgtcc cgccgacagc gggaagtccg tggtggcacc gcgcaccagg
    23821 ggaaaggggt tcgtcggacg tggttcgaac ttcaccatgt cggcctgcgc atcccttcgg
    23881 gcggggaggt ggatcgggac cggtggctcc ggacaggccc tagccctggg cggagctcag
    23941 cgccccgtcg acggccgcgg tgatggtgtc gacgctgcgg aacgtcgact ccttgagggc
    24001 gctctcgggc agttcgatgc cgaaggtgtc ctcgatgctc agcatcagcc cgaggcaggt
    24061 cagcgacgtc atgcccctgt cccacaggtt gtcgtcgtgg ttcagctcga agccgtgtcc
    24121 tgagaggttg agctgctggt cgatcagctt cctgacgatg tccacggtgg aggtgtcgga
    24181 ggtggtcact tcgccacctc gctcgcactc tggcgcccgc gcagatagcg cctgatccgg
    24241 cgggcgccga gcaggctgcc ctgtgcgtac cagaggatgt ccgggccgag cgcgtagtcg
    24301 atgcccagct ggtcgtaggc ctgcacacac cgcgtccggt agtactccgc gatctgtgcc
    24361 gtcgtcatct ggggcgccgc ttccgcgccg gtctcgaacc aggcggcgag gttgtgctcg
    24421 acgtactcgt cgatggacca ctcgatggtg cgggtgacga tcggttcccg ggtcggcgcg
    24481 aacatcgggt cgatggtgcc gggcttgccc tggagttcgt tcgcgacatg ctcggccagc
    24541 agcggcgcgc agtggaaccc gtcgcggtat gtgccggtca tcagatagag accggacggc
    24601 ggcagccagc cgatcatcgg gaagccgtcc agggtcaccg ggcggttccc ggcgagccac
    24661 tgcacgacct cgtggccggc ggcccgttcg tcgagctgct gcatcgagta ctgggcgagg
    24721 aacctgacgt cggccatcca ggtgacaccg gtgatggagt ccaccagccg gttggtggcg
    24781 ccgtagtact ccaggccgtc gccctgcggc acgacatgca gcccgcacgc gaacccgcgg
    24841 ttcggggtgc gcaccacgct gcggaacggg tcgccgccgg agcgccgcgc gatcatcgcg
    24901 aagccgagac cggggaacgt ggggatcagg tcgatgtcct cggacaccgt ccgcaccagc
    24961 gactcgctgt ggatgccggc cgccacgacg acggtgcccg cctcgatgac atggccgtcg
    25021 tcgagctcga ccccggtcac gacatcgcca ctgcccaaca gcctgcgcac cgaccggtcc
    25081 acctggaccg cgcccgtgtc gctcagccgg ctctccagcg cggtcagcac accgcgcgcg
    25141 tccacggcac cctcggtcgg caggtgcacg gcacgcagcg acctggtgtc cagacggggg
    25201 ttgaacccgg gtatgtcgtt cgggtccatc tcctcccacg gcttgccgta ctgatcgagc
    25261 gcgtcgatca tcgccttgaa gttgacggtg tccagctcgg cgccgatgga gttgagcacg
    25321 acgtgggtgt cgggggcgct ctgcagcggg cgtcccgtcc gggagtactc ctccagcttg
    25381 gccagcacgg cgggccaccg ctcgtgcgag ttgacgccca gctcgaagcg ggtgcgcgcg
    25441 gcgtcggtgc gtaacgactc cgtggtcgtc tcgccgaagc agcccagcat cgcgccggcg
    25501 gcctggctgg cccccgtctc gcgatggctc ggcccgacca cgacgacgga gcccatcccg
    25561 cgctccatca gttcgtcggc caggaacagg cccagggcgc cgttgccgac gatcacgacg
    25621 tcggcgtgct tcggcgtttc gttgattgcg gtttcagtca ctttcggaac tcccccttat
    25681 tccaggtggt agcccaataa agacaccgag aggtatggcg ccggcagcgt cgtgccgggg
    25741 ccatggaaag acggaaacgg tggtttccgt gaatgttgaa tcagagtgga atcagcgcgg
    25801 atgatttgac atacccgaag cggccgccgg atgcggctag gctttgatct tcgctggcac
    25861 ccccgtacct ggcgctgtgt cgtcgtcgac gctaccccgt catcgtcgcg acttgaaagt
    25921 gaaatcaggt ggtgacaagt gaatggcgta ttctcaccgc cggaacaatg tcttcctgtt
    25981 cgtccggagt atgttcgtgg tctgaaatca gccgactgtg agagaggctc gacattgtta
    26041 cctgaccccg ttgtcgctgg atcgcggccg gtgattgcag tggtcggagg aaaggtgaag
    26101 gtcctccgga aggcacatga cctggggctg gatgtggtgt acatccagca ccccgacgag
    26161 tacgacagca gccactggcc gtatgtcggt caggccctgc tcgtcgacta cgcggacacc
    26221 gagcgggtgt tgcccctggt gcggtcgttg cacgagacgt atccgttcca catggtcgtc
    26281 tcgccctggg agctggggct gctgccggcg gcgaagatcg acgacgccct cggtctcggc
    26341 ggcaacccgc tgcggacggt ggagatgctg ctcgacaagt cgaggatgcg cgcgcatctc
    26401 aatgcgtcgg gaatcagccc cgtcgccgcc gaggtgggcc ggaccgagcg ggatctgcgg
    26461 gagttcgccc gcgccaacgg actgcccgtc gtggtgaaac ccatcgacga ggccggcagc
    26521 atcggcatct tcaaggtgcg cgacgagtcg gacctggcgt cggtcgtgga acgctttcac
    26581 gccctcggca agcagatcga caagaaggac ctggccggag acctcgaccg gttcctgatg
    26641 gaggagtacc tggacggccc ggagatcagc gtcgagacac tgagcttcga cggccgccat
    26701 gtcctcgtgg gcgtgaccga caagctgtgc ctggactcgg gattcgtcga gaccggccac
    26761 tcccagccga gccgacaccc ggcagaactg ctgcgcgacg ccgaggacct ggtgatgaag
    26821 ttcctcgacg cgatcggact gcgccacggc ccggcgcaca ccgagatcaa gctgacctcg
    26881 cgcggcccgg tcatcatcga gtcccacaac cgcgtcggcg gcgaccgcat ccatgatctg
    26941 accgagatcg cctacggcgt cgacatggac cgctatacgc tcggttcgcg cttcggtctg
    27001 atcgagcccc ttgagcgggc accccaacca gtggcgggcg cggcgatccg cttcttcacc
    27061 ccaccgccgg gccgcgtcac cgaggtgacc ggcgccgaat ccatcgccgc cgaccccgcc
    27121 ctgtacgacc tggtcatctc ggtcgagccg ggcgacgagg tacggccgct cacctggagc
    27181 gacgaccggg tcggccatgt catcgcccga ggcgcgaccg ccgaggaggc gatcgccaac
    27241 tgcgagcggc tgctcgcggc ggtacgcatc cacacggagc cgatcacgtg agcaccgagc
    27301 agcccgacgt gcaggacccg ccgttccgcg agacgctgcg cgaactgccg ccccgggtgt
    27361 ggatcgtcag cctcggcatc ctcgtcaacc ggtgcggcaa cttcctgccg gtcttcatcg
    27421 tcctgtacct gaccagccag ggctattcac ccggagcggc ggggctggtc ctcggctccg
    27481 ccgggctggg caacgtcctc ggcagcgcgc tcggcggata tctcgccgac cagctcggca
    27541 ggcgctggac catcgccctg tccggcgtca ccaccgcggc tctgacggcg gtcatcccgg
    27601 tccttgacgg cctcgtcatg aacatcatcg tggtcggcct cgtcggcgcg gcgtcacagg
    27661 tgtaccggcc ggccgccgcg gccctgctga cggactccgt gaccaccaac cagcagcggg
    27721 tggcggcctt cgcggtcttc cggttcgcca tgaacctcgg cgccgccgcc ggcggcttcc
    27781 tcggcggctg gctcgcggcc aactcgtata cggagctgtt cctcggcaac gccgccgcct
    27841 gtctcctctt cggcgtgatc gcggtcctgc tgctgcgcga cgtaccgcac cgcgggtccg
    27901 aggaggacgg cgaggacggc tccgaggcca aggaacaggg cagttacaag ctggcgctcg
    27961 ccgaccgccg gctgcggcgg ttcctgctca tgaccgtcat cgccgagctc gtctacatcc
    28021 agtcgaccgt cggcctgccg ctgcacgtca ccgccagcgg actctcggag gccgacttcg
    28081 ggctgctcat cggcctcaac ggcgtgctcg tcctggtctg cgaactgccc atcgccgggc
    28141 tggtggtgaa acgccgggcc acccatgtcc tggcctgggg aaacctggcc accggcgtcg
    28201 gtctcgcgct gaccggcttc gcgaccgaca tgatctggct cgccgcgacc gtcgtcctgt
    28261 ggtcgctcgg cgagatgatg tactcctccg tggccaacgc ccacctcggc ggactctccc
    28321 cggccggcat ggtcggccgc taccaaggcc tctacggcgc cgccttcacc ctgggcaccg
    28381 gcgtcggccc gctcatcggc gccgcgatct acgcctacaa cgagtgggcc ctgtgggcgg
    28441 ccatcggcgt cgccggcgtg atctccgccc aactctgcct gccgggccgc cgcgcctcgg
    28501 cgccgccgga caccgagggg gacgggcccc ggcagcgggc ggacgaggcg tccgcctgaa
    28561 accgacccac ggcgaggggc ggcccctcag cactcgatga tgttgacagc caacccgccc
    28621 cgagccgtct ccttgtactt cacgctcatg tccgcaccgg tgtccttcat ggtcttgatg
    28681 accttgtcca gggacacctt gtgcgagccg tccccgcgca tcgccatccg cgcggcggtg
    28741 accgccttca ccgcggccat gccgttgcgc tcgatgcagg ggatctggac gaggccgccg
    28801 accgggtcgc aggtcaggcc gaggttgtgt tccatgccga tctcggccgc gttctcgacc
    28861 tgctcggggg agccgccgag cacctcggcc agcgcgcccg ccgccatgga gcaggcggag
    28921 ccgacctcgc cctggcagcc gacctcggcg ccggagatgg acgcgttctc cttgaacagc
    28981 atcccgatgg caccggcggc cagcaggaac cgtacgaccc cgtcctcgtc ggcaccgggc
    29041 acgaagttga tgtagtagtg caggaccgcg gggatgatgc cggcggcgcc gttcgtcggg
    29101 gcggtcacta ctctgccgcc cgccgcgttc tcctcgttca cggccatcgc gtagagcgtg
    29161 atccactcca tggcgagcgc cttggggtcg ccctcggagc gcagcttgcg ggccgtgttc
    29221 gccgcccgac gccgcacctt gagaccgccc ggcaggatgc cttcgcgcga catgccgcgc
    29281 gacacgcact cccgcatcac ccgccagatc tccagcagcc ccgcgcggat ctcctcctcg
    29341 gtgcgccagg cccgctcgtt ctccagcatc agcgaggaga tcgacagacc cgtctcctgc
    29401 gtcaggcgca gcagctcgtc accggtgcgg aaggggtact tcaggaccgt gtcgtcgagc
    29461 ttgatccggt ccgcgccgac cgcgtcctcg tcgacgacga agccgccgcc caccgagtag
    29521 tacgtcttgg acagcagctc cgcgccggac gcgtcgtacg cccacagcgt catgccgttc
    29581 gcgtggtagg ggagtgtctt acggcggtgc agcaccagat ccttgtcgaa gtcgaacggg
    29641 atctcgcgct cgtcgaggag cctgagccgc ccccctgact tgatcttctc cacccgttcg
    29701 tcggcgccct ccacgtccac cgtgcgcggc gaggcaccct ccaggccgag cagcaccgcc
    29761 ttcggggtgc cgtggccatg gccggtcgcg ccgagcgagc cgtacagctc ggaacgtatg
    29821 gaggcgaccg aggacagcac gtcctcgttg cgcagacggt gggcgaacat gcgtgccgct
    29881 cgcatcgggc cgaccgtgtg ggagctggac gggccgatgc cgatcgagaa caggtcgaag
    29941 accgagatgg ccacggggaa ctcctcaata cggggtgatg cgaaagattt ccgcggggtg
    30001 ccccgcacgc tcactgacca gtgtgcggga caccccacaa aaaggaacta cttgttcaga
    30061 ccggggtaca gcgggtgctt ttcggccagt gcccggaccc gggctttgag cgcctcgacg
    30121 tcgtacgacg gcttcagcgt ctccgcgatg acgtccgcga cctcggcgaa gtcctcggcc
    30181 tggaagccgc gggtggccag cgccggggtg ccgatccgca gccccgaggt caccatcggc
    30241 gggcgcgggt cgttggggac ggcgttgcgg ttgacggtga tgccgacctc gtggaggcgg
    30301 tcctcggcct gctgcccgtc cagctcggac tcgcgcaggt cgacgaggat gaggtgcacg
    30361 tcggtgccgc cggacagcac gttcaccccg gccgcacggg cgtcggcggc ggtgagccgc
    30421 tcggcgagga ggcgtgcgcc ctcgaccgta cggcgctggc gctccttgaa ctcgtcgctc
    30481 gcggcgacct tgaaggacac cgccttggcg gcgatcacat gctccagggg gccgccctgg
    30541 aagccgggga agaccgacga gttcagcttc ttcgcgaagt ccttcttcgc caggatgatg
    30601 ccgccgcgcg gcccgcccag ggtcttgtgg gtggtggagg tgacgacgtc cgcgtactcg
    30661 accgggttcg ggtgcagccc ggccgcgacc agcccggcga agtgcgccat gtcgacccac
    30721 aggtaggccc cggcctcgtc cgcgatgcgc cggaactcgg cgaagtccag ctgccgcgga
    30781 tacgccgacc acccggcgat gatcaccttc ggccggtgct ccttggcgag ccgctcgacc
    30841 tcggccatgt ccaccagacc ggcctcgtcg acgtggtagg cgacgacgtt ga
//