LOCUS       NZ_BNBM01000002        21941 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces lanatus strain JCM 4588 sequence02, whole genome
            shotgun sequence.
ACCESSION   NZ_BNBM01000002
VERSION     NZ_BNBM01000002.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces lanatus
  ORGANISM  Streptomyces lanatus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 871820)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 61X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014655715.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 05:46:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,254
            CDSs (total)                      :: 9,172
            Genes (coding)                    :: 8,973
            CDSs (with protein)               :: 8,973
            Genes (RNA)                       :: 82
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 199
            CDSs (without protein)            :: 199
            Pseudo Genes (ambiguous residues) :: 0 of 199
            Pseudo Genes (frameshifted)       :: 83 of 199
            Pseudo Genes (incomplete)         :: 153 of 199
            Pseudo Genes (internal stop)      :: 16 of 199
            Pseudo Genes (multiple problems)  :: 50 of 199
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:57:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 323686
            Orig. end                         :: 345627
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BNBM01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21941
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21941
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21941
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11941](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11941)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(1071..1086)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 25.34"
                     /tool="antismash"
     misc_feature    1092..1107
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 22.4"
                     /tool="antismash"
     gene            1162..2208
                     /locus_tag="IE325_RS06650"
                     /old_locus_tag="GCM10018780_13440"
     CDS             1162..2208
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011028391.1"
                     /locus_tag="IE325_RS06650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_13440"
                     /product="chitinase"
                     /protein_id="WP_190068772.1"
                     /transl_table=11
                     /translation="MLRRALSLLTAALATACLTQLPAASPASAADTCAVKSKPSGKVLQ
                     GYWENWDGAANGVHPPFGWTPITDSRMAAHGYNVINAAFPVIRSDGTALWEDGMDSGVK
                     VATPAEMCAAKASGQTILMSIGGATAGIDLNSTAVADKFVATIVPILKKYNFDGIDIDI
                     ETGLTGSGNIAQLSTSQANLIRIIDGILAQMPSNFGLTMAPETAYVTGGSVTYGSIWGA
                     YLPVIKKYADNGRLWWLNMQYYNGSMYGCSGDSYSAGTVEGFTAQTDCLNKGLVIQGTT
                     IKVPYDKQVPGLPAQSGAGGGYMSPSLVAQAWRHYGSSLKGLMTWSINWDGSKNWTFGD
                     NVKSLQGR"
     gene            complement(2191..2721)
                     /locus_tag="IE325_RS06655"
                     /old_locus_tag="GCM10018780_13450"
     CDS             complement(2191..2721)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014133469.1"
                     /locus_tag="IE325_RS06655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_13450"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_190068773.1"
                     /transl_table=11
                     /translation="MKLSDGVIALSPLVPADAEAHLAGEDEQLVRWLSGGPGTREGVDA
                     YIRHCGEQWAAGGSLRAFGIRVGVGETLAGTIDLRFAAEGLTRGQVNVAYGLYPAWRGR
                     GLATRAVLLVCRYAAGEGVSGAVIQVEPGNAASAAVARRAGFAPGGQRFTEDGTLLDRY
                     VLDLRAPGSTALQ"
     gene            complement(2718..3365)
                     /locus_tag="IE325_RS06660"
                     /old_locus_tag="GCM10018780_13460"
     CDS             complement(2718..3365)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126587.1"
                     /locus_tag="IE325_RS06660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_13460"
                     /product="1,4-alpha-glucan branching protein"
                     /protein_id="WP_190068774.1"
                     /transl_table=11
                     /translation="MAVIHHTTLKPTKLELLTSWLPTRPWYAGAGAPRLHKSGGFRLDD
                     PAGEVGIEFMVATDEVGAVSYLVPLTYRGAPLDGAEHALVGTMEHGVLGPRWAYDGCHD
                     PVLVGQLWALIEGRAEAQAQSLTDVVDREVTRSYGGPGLGAHGPTAVSEDSEGTWLTAP
                     DGTTLLLHRVLRPAPHGVPEGAIGHVGGAWQVPDGPRVHGLFASLYAHGTAP"
     misc_feature    complement(3381..3392)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.42"
                     /tool="antismash"
     gene            3566..4615
                     /locus_tag="IE325_RS06665"
                     /old_locus_tag="GCM10018780_13470"
     CDS             3566..4615
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018836476.1"
                     /locus_tag="IE325_RS06665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_13470"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_190068775.1"
                     /transl_table=11
                     /translation="MRARRVSLVARCVRGLEPALGTEILRTGSATIDLIGHREVSFRTD
                     LNGDGDGVRLRTADDVFLLAHRRHDIGPHKTDLSALADLARAVDLEGLTKARRGFGDGI
                     EISASFLGRRTYNRYDIEDTVGRVLAERAGVPYHSRRDGDAPPPGHSGWRLTLDGTHAT
                     LLLRLGRRPTHRRAYKSATIAGTLHPPVAAAMAQAAELRPGQRVLDPCCGAGTLLIEAH
                     HTTPGTTLLGFDLAPAARRAARQNAGRLPVTIRHGDAGALPLADRSVDRVLCNPPWGDQ
                     VDPGGRLAGHPERWWRELARVLSDEGRAIVLLPDARGLGRALALGLSPVHVQQLSLFGS
                     RPLLVRLER"
     gene            complement(4612..5223)
                     /locus_tag="IE325_RS06670"
                     /old_locus_tag="GCM10018780_13480"
     CDS             complement(4612..5223)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326375.1"
                     /locus_tag="IE325_RS06670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_13480"
                     /product="LysE family translocator"
                     /protein_id="WP_190068776.1"
                     /transl_table=11
                     /translation="MSLAFLLTTLVVVATPGTGVVYTLAAALSRGRRASVVAAFGCTLG
                     IVPHILATVTGVAALLHASATAFQVLKYAGVAYLLYMAWATVRDKDAIVVEEGAAPPSS
                     GRVIMRGVLINILNPKLTLFFFAFLPQFVDPGAANAVPRMLGLSAVFMLATFLVFAAYG
                     VLAASVRSHVTSRPRVMTWLRRTFAGSFVALGAKLALTAR"
     misc_feature    complement(5291..5300)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.42"
                     /tool="antismash"
     gene            complement(5346..6728)
                     /locus_tag="IE325_RS06675"
                     /old_locus_tag="GCM10018780_13490"
     CDS             complement(5346..6728)
                     /EC_number="6.1.1.14"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005479171.1"
                     /locus_tag="IE325_RS06675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_13490"
                     /product="glycine--tRNA ligase"
                     /protein_id="WP_190068777.1"
                     /transl_table=11
                     /translation="MAADKIDTIVSLSKRRGFVFPCSEIYGGQRAAWDYGPLGVELKEN
                     LKRQWWRYMVTSREDVVGIDSSVILAPEVWVASGHVATFTDPLTECTSCHKRFRADHLE
                     EAYEAKKGHLPENGLADVNCPNCGNKGQFTEPKQFSGLLSTHLGPTQDSGSIAYLRPET
                     AQGIFTNFAQVQTTSRRKPPFGIAQMGKSFRNEITPGNFIFRTREFEQMEMEFFVKPGE
                     DEKWQEYWMEQRWNWYTGLGLREENMRWYEHPKEKLSHYSKRTADIEYRFQFGGNEWGE
                     LEGVANRTDYDLGAHSKASGQDLSYFDQEAGERWTPYVIEPAAGVGRAMLAFLLDAYVE
                     DEAPNAKGKMEKRTVLRLDHRLAPVKVAVLPLSRNPELSPKAKGLAQALRQNWNIEFDD
                     AGAIGRRYRRQDEIGTPFCVTVDFDTLEDNAVTVRERDSMKQERVSLDQIEGYLASRLI
                     GA"
     misc_feature    complement(6833..6851)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.72"
                     /tool="antismash"
     misc_feature    6835..6849
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.93"
                     /tool="antismash"
     misc_feature    complement(6850..6863)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.27"
                     /tool="antismash"
     misc_feature    6850..6864
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.03"
                     /tool="antismash"
     misc_feature    complement(6857..6871)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: strong, score: 25.32"
                     /tool="antismash"
     misc_feature    complement(6858..6873)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.6"
                     /tool="antismash"
     gene            6871..7836
                     /locus_tag="IE325_RS06680"
                     /old_locus_tag="GCM10018780_13500"
     CDS             6871..7836
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1252: cation ABC
                     transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003976297.1"
                     /locus_tag="IE325_RS06680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_13500"
                     /product="metal ABC transporter solute-binding protein,
                     Zn/Mn family"
                     /protein_id="WP_190068778.1"
                     /transl_table=11
                     /translation="MNVRRPHISGIALAAVTALGIGTLSACSSDSAAAGNTDKFDVVAS
                     FYPMAFLAEEIGGDHVKVTSLTEPGQEPHDLEISAQQRAQLEESDAALFLKGLQPSVDE
                     AVGQSGLKTKIDAATLTKLEDHGNLEDSHEHEGEEAHSEEEEEHARDPHIWLDPVKYAE
                     VAKGVGAAFEKADPDHAADYKKNTDALVKKLGELNTEFTDGLKNTKSKVFFTNHAAFGY
                     LAERYGLTQEAISGLDPESEPSPARIKELQQEAKADGVTTVFYETLVSDKTAKTLADDA
                     GLKTDVLDPLEGITDKSKGDDYFAVMQANLTALKTALGAK"
     gene            7845..8624
                     /locus_tag="IE325_RS06685"
                     /old_locus_tag="GCM10018780_13510"
     CDS             7845..8624
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004001435.1"
                     /locus_tag="IE325_RS06685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_13510"
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="WP_190069214.1"
                     /transl_table=11
                     /translation="MEDGMTEPVISLRGVRAELGSRPVLRGIDLTVGHGEVVALLGANG
                     SGKSTAVRSVIGQVPVSAGEIELFGTARARFRDWSRVGYVPQRTTAAGGVPATVGEVVS
                     SGRLSRTRFGVFRKADHAAVRHALELVGMADRVKDSVNALSGGQHQRVLIARALASEPE
                     LLIMDEPMAGVDLASQEVLARTLREQVAAGATVLLVLHELGPLEPLIDRAVVLRDGCVL
                     HDGPPPKAVGQHALPGHDHVHPHAAHDAEPIRTGLLS"
     gene            8624..9526
                     /locus_tag="IE325_RS06690"
                     /old_locus_tag="GCM10018780_13520"
     CDS             8624..9526
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_process="GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1245: ABC transporter
                     protein, integral membrane"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010042134.1"
                     /locus_tag="IE325_RS06690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_13520"
                     /product="metal ABC transporter permease"
                     /protein_id="WP_190068779.1"
                     /transl_table=11
                     /translation="MDFLNYDFMQRALLAAVLVGITAPAVGIYLVQRRQALMGDGIGHV
                     AMTGVGLGFLLSWSPVWMATLVSVLGAIAMELIRWYGRMRGDLALAMLFYGGMAGGVML
                     INLAPNGSNANLTSYLFGSLSTVSESDVTAIIVLAAFVVLVTLGLRRQLFAVSQDEEFA
                     RVTGLPVRALNLLTAITAAVTVTVAMRVVGLLLVSALMVVPVAAAQQLTRSFAATFAIA
                     VAIGVTVTIGGTVTSYYQDVPPGATIVLLTIGAFIALTALATPLARRRARALAAAQPST
                     DPAECAIPASRGTDGKVSV"
     gene            9586..9996
                     /locus_tag="IE325_RS06695"
                     /old_locus_tag="GCM10018780_13530"
     CDS             9586..9996
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1266: hydrogen
                     peroxide sensitive repressor"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009188505.1"
                     /locus_tag="IE325_RS06695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_13530"
                     /product="Fur family transcriptional regulator"
                     /protein_id="WP_190068780.1"
                     /transl_table=11
                     /translation="MTTAGPPVKGRATRQRAAVAAALDEVDEFRSAQELHDMLKHKGDS
                     VGLTTVYRTLQNLADAGEVDVLRTSDGESVYRRCSTGEHHHHLVCRVCGKAVEVEGPAV
                     EKWADAIAAEHGYVNVAHTVEIFGTCAECAAR"
     gene            complement(10001..11941)
                     /locus_tag="IE325_RS06700"
                     /old_locus_tag="GCM10018780_13540"
     CDS             complement(10001..11941)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012705.5"
                     /locus_tag="IE325_RS06700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_13540"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_190068781.1"
                     /sec_met_domain="phytoene_synt (E-value: 5.4e-29, bitscore:
                     96.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.7e-28,
                     bitscore: 95.2, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="PT_FPPS_like (E-value: 6.4e-58, bitscore:
                     191.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARWEIDKFNDCLTASGITDARLRNSYRTCFQLALKTDRGMAMPG
                     ALLPARHRPALAAVGALVRWVDDLADGDGSGPARFDDETGLLLEEIGAGTSEHPVRAAL
                     VHAITRFPLPRQPVRELIETTRGDIGRRDGFATEEELSAFARGVAGAPVRMSLPLLGCS
                     GDDGDDPVLDELAMAFGEGLDRVDNLRDLSQDLARGWAGISDEMLRACGTDRAELLERR
                     ATPGVLEALGRAARHARELLTYGDKLAAGLPPYGGAAIDAMGSLYRSHLDAVTSDLPAV
                     LRRVPRIRKAELKRLALLTLRQSPTCTEDAGITTAASVAQDIRQWPTHRAARAELTRRV
                     TGADDDALARIQQHALLPPGKLLRPVLVLESAGSVGGSPESVLPVAVAMEMTHVASLMH
                     DDIIDGDQQRRGRDTAPRRFGQGFALLAANALYMSAMQSLTECLTRGISAEQVNEAWHG
                     VSATAEAMARGVAMELEIEDDLTCGQERYLEMARLKTAVLFGLSCRLGAQLSGGGEHAD
                     ALDGFGTALGMAFQIRDDLLPYDGSAQDVGKDPASDLRNHRPTLPVLLAHEHAGAEERA
                     RLDAVWRAPDTEAAFPELRELLQETGALALARSAADAYAGQAQDLLHRLPDTPHRTRLR
                     YLAQQSARRSH"
     gene            complement(11910..12299)
                     /locus_tag="IE325_RS06705"
                     /old_locus_tag="GCM10018780_13550"
     CDS             complement(11910..12299)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039352.4"
                     /locus_tag="IE325_RS06705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_13550"
                     /product="DUF6114 domain-containing protein"
                     /protein_id="WP_190068782.1"
                     /transl_table=11
                     /translation="MSWTAWRRSRPFWGGLLIMAGGVEVVWTTWGGLGLVQFSGLAGAT
                     GWLVCVAALTAGVLAWWSPDRCVLPGVLALAIAFVSLVMANLGGLFLGFLLLSTGGAMT
                     VTWAPGPYSEEERQRRGALGDRQVQ"
     gene            complement(12296..12853)
                     /locus_tag="IE325_RS06710"
                     /old_locus_tag="GCM10018780_13560"
     CDS             complement(12296..12853)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE325_RS06710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10018780_13560"
                     /product="DUF6230 family protein"
                     /protein_id="WP_190068783.1"
                     /transl_table=11
                     /translation="MRGEWRGGVRRRHCAVLLAAVNGAAFALLASGNAGAIEVSMAGRS
                     PVTITADRVTVSGLSLAPGAAPGGRTDAAFVELFKDFRAERVCLTSPVRVPLAGRFMVH
                     IGMESMSASGFTIEAAGLSASRLSMADAGLAVEAEPSRPFELTAGSFKASQVTIKPRAY
                     TAATMSARGFQAGVSRDGDGCP"
     gene            complement(13106..13945)
                     /locus_tag="IE325_RS06715"
                     /old_locus_tag="GCM10018780_13570"
     CDS             complement(13106..13945)
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020116257.1"
                     /locus_tag="IE325_RS06715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_13570"
                     /product="isoprenyl transferase"
                     /protein_id="WP_190068784.1"
                     /transl_table=11
                     /translation="MAVSGFLGRRRREYRAPEPHPSGARAPKLPGELIPKHVAIVMDGN
                     GRWAKERGLPRTEGHKVGAERVLDVLQGGVEMGVGAISLYAFSTENWKRSPDEVRFLMN
                     FNRDFIRKTRDQLDELGIRVRWVGRMPKLWKSVAKELQIAQEQTKDNDKLTLYFCMNYG
                     GRAEIADAAQALAEDVKAGRLDPSKVNEKTFAKYMYYPDMPDVDLFLRPSGEQRTSNYL
                     LWQSAYAEMVFQDVLWPDFDRRDLWRACVEFASRDRRFGGAIPNEELVAMEGRREED"
     gene            complement(13985..14731)
                     /gene="recO"
                     /locus_tag="IE325_RS06720"
                     /old_locus_tag="GCM10018780_13580"
     CDS             complement(13985..14731)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recO"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127703.1"
                     /locus_tag="IE325_RS06720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_13580"
                     /product="DNA repair protein RecO"
                     /protein_id="WP_190068785.1"
                     /transl_table=11
                     /translation="MSLFRDDGIVLRTQKLGEADRIITLLTRGHGRVRAVARGVRRTKS
                     KFGARLEPFSHVDVQFFARGSELIGRGLPLCTQSETIAPYGGGIVTDYARYTAGTAMLE
                     TAERFTDHEGEPAVQQYLLLVGALRTLSRGEHAPHLVLDAFLLRSLAVNGYAPTFSDCA
                     KCGMPGPNRFFSVASGGSVCVDCRVPGSVVPSPQTLELLGALLTGDWETADSCEPRHVR
                     EGSGLVSAYLHWHMERGLRSLRYVEK"
     gene            complement(14758..15378)
                     /locus_tag="IE325_RS06725"
                     /old_locus_tag="GCM10018780_13590"
     CDS             complement(14758..15378)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015660516.1"
                     /locus_tag="IE325_RS06725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_13590"
                     /product="DUF1266 domain-containing protein"
                     /protein_id="WP_190068786.1"
                     /transl_table=11
                     /translation="MALWRWRRRGVKATRRYPVPLTMHQLWMVSLSAPVSRDKSASRTT
                     LYPYVRIDDDSARRWLADQWEITSREGLVGRLDELAHSGYRARAYRQTGVSPLAWDAAL
                     YVDIARRGFACGLIDEGDAWTALKNIVPTVVRTYASWEEYAGHYLLGRQVWRAALRDAE
                     ESDLPASQAVADEHLRALLDAGNRASPWNLAPWDSISHPDRPR"
     gene            complement(15409..15624)
                     /locus_tag="IE325_RS06730"
                     /old_locus_tag="GCM10018780_13600"
     CDS             complement(15409..15624)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019064131.1"
                     /locus_tag="IE325_RS06730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_13600"
                     /product="hypothetical protein"
                     /protein_id="WP_190068787.1"
                     /transl_table=11
                     /translation="MKPPIGAYVVDTRSGRIGVVMGHEGPYVQLRPYGGGKEWDAEPAS
                     VRTATPAERLRAATAYANARSRGEVP"
     gene            complement(15621..15827)
                     /locus_tag="IE325_RS45985"
     CDS             complement(15621..15827)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011028396.1"
                     /locus_tag="IE325_RS45985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_229911691.1"
                     /transl_table=11
                     /translation="MTARHSARCVEEAEDAVKELRAALEKAGITLPTLRIDPASLAREA
                     PCPLVELGRCSVETAQRLATVLR"
     gene            15943..16776
                     /locus_tag="IE325_RS06735"
                     /old_locus_tag="GCM10018780_13610"
     CDS             15943..16776
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011028397.1"
                     /locus_tag="IE325_RS06735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_13610"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_190068788.1"
                     /transl_table=11
                     /translation="MANGSRMAAWEFFGSELKRHRENAGITQVELGARVFVSGGYIGQF
                     EQAIRKPQLDVAQRIDEVLQTDGFFERTWRQLINDKRYADYFGPVVELERLATKICEYA
                     PTVVPGLLQTAAYAEAVTIAANPFVTNAYVEEKVMARLERADILKDATRPEYWAILHEN
                     VLRIPVGGPEAMAEQLEHIAHLMRERTVWLTVIPYAVGAHASMIGDLRLMEFEDAPPVA
                     YTETSFSGTLLDDPAVVKRAQRAYDLLRGTALSPEASLALIESAAEDFRRCASTT"
     gene            16758..16952
                     /locus_tag="IE325_RS06740"
                     /old_locus_tag="GCM10018780_13620"
     CDS             16758..16952
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007381903.1"
                     /locus_tag="IE325_RS06740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_13620"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_190068789.1"
                     /transl_table=11
                     /translation="MREYDLSSANWRKSSHSNGEGGNCLEVADGVPGVIPVRDSKLASD
                     SPVLLIPAPAWDRFLTSLR"
     gene            complement(16936..17817)
                     /locus_tag="IE325_RS06745"
                     /old_locus_tag="GCM10018780_13630"
     CDS             complement(16936..17817)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007503936.1"
                     /locus_tag="IE325_RS06745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_13630"
                     /product="DUF6879 family protein"
                     /protein_id="WP_229911692.1"
                     /transl_table=11
                     /translation="MPKMFWRIVITAGAAGGAFLLTSILSEDDGNIWQWVASIVIGSAA
                     LIVQYLIDFGERFEKVDTRFNEILAATTLFSQVDGSVLRSDEVTRLVLGYTKVREQGGD
                     IVQAFAEKELGRLAKMMEGLGSGNADCPGENHEWLIDITDCVKMTLDATSTSVDREFWT
                     SGPGERYLDAQEKAIKRRGVEIRRVFVVLDEEEVTPDLRALCERHRRRGIDARIAVRSL
                     MESNPRVNDFIIFDGELCHETKPDQENKPDSTLLSAEPDHIEDRETQFAELWAEAERQG
                     TTTPAPRVTAET"
     gene            complement(17925..18890)
                     /locus_tag="IE325_RS06750"
                     /old_locus_tag="GCM10018780_13640"
     CDS             complement(17925..18890)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004001418.1"
                     /locus_tag="IE325_RS06750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_13640"
                     /product="SCO2521 family protein"
                     /protein_id="WP_190068791.1"
                     /transl_table=11
                     /translation="MTAALGQPARSVLACGEVRTCLLPSFQAFDARAAAQLLRLRADEP
                     VRISERPSMYALSPEILTGVDCRLPASNGSKVRSVGTVAARAALTEGRLLQATAYFSLP
                     AAGPDIRRPWGQYLVRPGLVEPFGKLPQQATVEGMLRGARRGELDLGMIAEGLLAALRR
                     HALLDRRVPFKSSPTRLRWVARRGDQQASLVNFTVAEGGLRTMELRLPEHIPAAAAAGL
                     CEDLALHDWLLTTVQHMLDNSRLGTADGPSVVEALHPVVVHLLHLWMPRAHVDPALGHL
                     WDVLEEKPGFSRQWENLSRRIRDRLALQAVAMPHQALSTS"
     gene            complement(18892..19872)
                     /locus_tag="IE325_RS06755"
                     /old_locus_tag="GCM10018780_13650"
     CDS             complement(18892..19872)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007503938.1"
                     /locus_tag="IE325_RS06755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_13650"
                     /product="SCO2522 family protein"
                     /protein_id="WP_190068792.1"
                     /transl_table=11
                     /translation="MTEAVFQETTAELRTQAVPLAHLSLELGHLYMEDFEAGPKRLGEH
                     FAEVRVWADAVRASLERRTQRPRISTCFLIDDYFTRFSTPAELIPMVLKEAEKAGLVID
                     YLARESGCAVADRIELAESVMHRLVESPPPGSYGSRPPVSQTGWLANGERTPSASRSAL
                     GAVKGWESPQETAARNHSIFMDVELWSEKDGRRLWSCPFLAAVWQLARLGLLRHLGEPV
                     LVPREWGGADFPHDWDRLPPLIKLTDTRAAFSAYRTCSMMPNRFIAVEDAVRLILDQTD
                     VDAGALQQVAERSAAERMPVPAAVAQRATYVFYEEPADSSEAEGT"
     misc_feature    complement(19228..19230)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(19869..20786)
                     /locus_tag="IE325_RS06760"
                     /old_locus_tag="GCM10018780_13660"
     CDS             complement(19869..20786)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007503939.1"
                     /locus_tag="IE325_RS06760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_13660"
                     /product="SCO2523 family variant P-loop protein"
                     /protein_id="WP_190068793.1"
                     /transl_table=11
                     /translation="MLIFAASDKGGTGRSVTSANLAYHRAMAGDDVCYLDFDFGSPTAA
                     AVFDVADARQQTEDRGLHAYLIGEVSEPARIDVWSETEHQVLRFPPPGSGRLVLMPGDV
                     SGGEFAISGDNLRRCVDLLTTLYYEFDLVVVDLSAGRSYAVDMVLEATAQAEMREITAR
                     WLVFHRWTRQHVAAAASLVFGKRGILAGGADRGHDEEALRNSIRFVRAAVPDPESPLWS
                     QVSPTQSAWMRKTDGDLKQLASTHGIGYSQVLGSVPLEPVLQWREQLITDEDVLDSQIA
                     NQETWQALSQLAGRLTDDKYWEQV"
     misc_feature    complement(21388..21404)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 21.87"
                     /tool="antismash"
     misc_feature    complement(21838..21853)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.62"
                     /tool="antismash"
ORIGIN
        1 ccatcagcgg ggccgggtag cggtcgccgg ccgccgcgtc cgccgggacc gcctgctcga
       61 tcgccgcgag gtcggcggcg tccagcgtga cgtccagcgc gcccagcgac tcgtcgagcc
      121 gctcgcgggt gcgggcgccg accagcggca cgatgtcctc gccccgggag agcacccagg
      181 cgatggcgat ctgcgcgacg gagacgccct tctgtccggc gatcttccgc agcgcctcga
      241 cgaggtcgag gttgtgccgg aggttgtcgc cctggaagcg gggcgagtgc gcccggaagt
      301 cgttggcggc gagctgccgg tcatgggtga agtgcccgga gatcaggccg cgcgacagga
      361 cgccgtacgc ggtgatggag atgcccagct cacgggtggt cgggaggacc gaatcctcga
      421 tgccccggga gatgagcgag tactcgatct ggaggtcgga gatgggggcc gtcgcggcgg
      481 cccggcggat gatgtcggcg cccacctcac tcagcccgac atggcggacg taccccttct
      541 cgatcagttc cgagatcgcg ccgaccgtct cctcgatcgg tacgtcgggg tcgagccggg
      601 cgatccggta gacgtcgatg tggtcgacgc cgaggcgctg cagcgagtac gcggcgaagt
      661 tcttcacggc ggcgggtcgg ccgtcgtagc cggcccactc gccgtccggg gagcgcaggg
      721 cgccgaactt cacgctggtc agggcctgtt cgcgcagggc ggcgggcgcg gtgcgcaggg
      781 cctcgccgat cagcatctcg ttgtgcccca tggcgtagaa gtcgccggtg tcgagcaggg
      841 tcacgcccgc ttccagggcg gcgtggacgg tggcgatcga ctcggcccgg tccgcgccgc
      901 cgtagagcgc ggacatgccc atgcagccga ggccgagggc ggagacctgg gggccggtgg
      961 ttccgagggt gcgggtttgc atcgtcatgc ctccaccatg ccctaacagc tgacagattt
     1021 caatatctgt cattccatac ttgtcagcgc gcctcacgcg gccatctcaa tgtggtccag
     1081 acctattgac gagaggtctg gaccacgagc actgtcatgc ctacgacatc gcccgccccg
     1141 acccccaccg ggaggccccg tatgctccgc cgcgccctca gcctgctcac cgcggcactg
     1201 gcgaccgcct gtctcaccca gctccccgcc gcatcccccg cgtccgccgc cgacacctgc
     1261 gccgtcaagt ccaagccgtc cggcaaggtc ctccagggct actgggagaa ctgggacggc
     1321 gccgccaacg gcgtccaccc gcccttcggc tggaccccga tcaccgactc ccgcatggcg
     1381 gcgcacggct acaacgtgat caacgcggcc ttcccggtca tccgctccga cggaacggca
     1441 ctctgggagg acggcatgga cagcggggtg aaggtggcaa cccccgcgga gatgtgcgcg
     1501 gcgaaggcct ccggccagac gatcctgatg tccatcggcg gcgccacggc cggcatcgac
     1561 ctcaactcga ccgccgtcgc ggacaagttc gtcgcgacga tcgtcccgat cctgaagaag
     1621 tacaacttcg acggcataga catcgacatc gagaccggcc tgacgggcag cggcaacatc
     1681 gcccaactct ccacgtccca ggccaacttg atccgcatca tcgacggaat cctcgcccag
     1741 atgccatcga acttcggcct gaccatggcc ccggagacgg cctacgtcac cggcggcagc
     1801 gtcacctacg gctcgatctg gggcgcctac ctccccgtca tcaagaagta cgccgacaac
     1861 ggccgcctgt ggtggctgaa catgcagtac tacaacggca gcatgtacgg ctgctccggc
     1921 gactcctact ccgccggaac cgtcgagggc ttcaccgccc agaccgactg cctcaacaag
     1981 ggtctcgtca ttcaaggtac gacgatcaag gtgccgtacg acaagcaggt ccccggcctg
     2041 cccgcccagt cgggcgcggg cggcggctac atgtcaccgt ccctcgtcgc ccaggcctgg
     2101 cggcactacg gcagctcgct caagggcctg atgacctggt cgatcaactg ggacggttcg
     2161 aagaactgga ccttcggcga caacgtgaag tcactgcagg gccgttgatc ccggcgcacg
     2221 caggtcgagg acatagcggt cgagcaacgt cccgtcctcg gtgaaccgtt gcccgccggg
     2281 cgcgaacccg gcccggcggg cgacggcggc ggacgctgcg ttgcccggct ccacctggat
     2341 caccgccccg ctcacgccct caccggccgc gtaccggcag accaggagga cggcccgggt
     2401 ggcgagcccc cgcccccgcc acgccggata gagcccgtag gcgacattga cctgcccccg
     2461 ggtgagcccc tccgccgcga aacgcagatc gatggtgccc gcgagcgtct caccgacgcc
     2521 cacccggatc ccgaacgcac gcagcgaacc gcccgccgcc cactgctccc cgcagtgccg
     2581 gatataggcg tcgacgccct cacgcgtacc gggaccgcca ctcagccagc ggaccaactg
     2641 ctcgtcctca cccgcgagat gggcctcggc gtcggccggg accagcgggg agagggcgat
     2701 caccccgtcg gacagcttca cggcgccgtt ccgtgggcgt acagggacgc gaacagcccg
     2761 tgcacgcgcg gcccgtccgg cacctgccag gcaccgccga catggccgat ggccccctcg
     2821 gggacgccgt gcggtgcggg ccgcaggacg cggtgcagca ggagggtcgt accgtccggc
     2881 gcggtcagcc aggtgccctc ggagtcctcg gagacggccg tgggcccgtg ggctccaagc
     2941 cccggaccgc cgtaggagcg agtgacctcc cgatccacca catcagtgag actctgcgcc
     3001 tgggcctcgg cccgcccctc gatcagcgcc cacaactgcc cgaccagcac cgggtcatgg
     3061 cagccgtcgt aggcccagcg cggccccagc accccgtgct ccatggttcc gacgagggca
     3121 tgctcggcac cgtcgagagg ggcaccgcga taggtcagcg gcaccaagta gctcaccgcc
     3181 cccacctcat cggtggccac catgaactcg atcccgacct cccccgccgg gtcgtccagc
     3241 cggaagccgc cggacttgtg cagtcggggc gcaccggcac cggcgtacca agggcgggtg
     3301 ggcagccagg aggtgaggag ttccagcttg gtcggcttga gggtggtgtg atgaatgacg
     3361 gccatgccgc aggctctcac gaaagctttt gccacaacac ggcaacccgt cactctggta
     3421 cgctttttcg atcatgacga tgacgtactt cttccacctt cgctagtcgc tccgtcggca
     3481 cgacgcggtt caccccggcg ccgacgatgc gggacggccg tccactccgc cgtcccgggc
     3541 tgcgacgtgg gagaagacgt acatcatgcg cgcacggcgt gtgtccttgg tggctcggtg
     3601 cgtacgaggg ctggagcccg cactcggcac ggagattctg cggacgggtt ccgcgaccat
     3661 cgacctgatc ggccaccgcg aggtgagctt cagaaccgac ctgaacggag acggggacgg
     3721 ggtccggctg cggaccgccg acgatgtctt tctgctggcc catcgccggc acgacatcgg
     3781 cccgcacaag accgacctgt ccgccctggc cgacctggcc cgcgcggtcg acctggaggg
     3841 cctgacaaag gcacgccggg gcttcggcga cggcatcgag atctcggcgt ccttcctcgg
     3901 gcgccggacg tacaaccgct acgacatcga ggacaccgtc ggccgggtcc tggccgagcg
     3961 cgcgggcgtc ccgtaccact cacgccgtga cggcgacgcg cccccgcccg gccacagcgg
     4021 ctggcgcctc accctcgacg gcacccacgc caccctgctg ctgcgcctgg gacggcgacc
     4081 gacgcaccgg cgcgcctaca agagcgcgac gatcgcgggc accctgcatc caccggtagc
     4141 cgccgcgatg gcccaggcgg ccgaactccg cccaggtcaa cgggtgttgg acccctgctg
     4201 cggtgcgggc accctcctca tcgaggccca ccacaccacc cccggcacca cgctcctcgg
     4261 cttcgacctc gccccggccg cacgccgggc ggcccgccag aacgccggcc ggctccccgt
     4321 gaccatccgc cacggcgacg ccggcgccct ccccctcgcc gaccgcagcg tcgaccgggt
     4381 gctgtgcaat ccgccgtggg gcgaccaggt cgacccgggc ggccgtctcg ccgggcaccc
     4441 ggagcgctgg tggcgcgagc tcgcccgggt tctctccgac gagggacggg cgatcgtgct
     4501 gctgcccgac gcccgggggc tcggccgcgc cctggcgctc ggcctgtccc ccgtccacgt
     4561 acagcagttg agcctgttcg ggagccggcc gctcctggtc cgcctcgaac gctaacgggc
     4621 ggtgagcgcc agcttcgcgc ccagggccac gaacgaccct gcgaaggtcc gccgcagcca
     4681 tgtcatcacc cggggccggg aggtgacatg gctgcgtacg gaggccgcga ggacgccgta
     4741 cgcggcgaag accaggaacg tcgcgagcat gaacaccgcg ctgagcccca gcatgcgcgg
     4801 caccgcgttc gccgcgcccg gatccacgaa ctgcggcaga aaggcgaaga agaacaacgt
     4861 cagcttcgga ttgaggatgt tgatcagcac cccgcgcatg atcacccgcc ccgaggaagg
     4921 cggcgcggcc ccctcctcca ccacgatggc gtccttgtcc ctgaccgtcg cccaggccat
     4981 gtacagcagg taggcgacac ccgcgtactt cagcacctgg aacgcggtcg cgctcgcgtg
     5041 cagcagcgcg gcgacaccgg tgaccgtggc caggatgtgc ggcacgatcc cgagggtgca
     5101 cccgaaggcg gcgacgacac tcgcgcgccg cccccgggac agtgcggcgg cgagcgtgta
     5161 gacgacaccg gtgccggggg tggcgacgac gacgagggtg gtgaggagga aggcgagact
     5221 catggccgta agccttgtgc cgccgcgccc cgggaaacag ggccaatcga cgtccccgct
     5281 cccggaccaa tcaaaaaagg ctgacgggag acatcgcgtc ccccgtcagc cgcttcgact
     5341 aatccctacg caccgatgag ccggctcgcc aggtacccct cgatctggtc gagggacacc
     5401 cgctcctgct tcatcgagtc gcgctcacga accgtgaccg cgttgtcctc aagcgtgtcg
     5461 aagtcgaccg tcacacagaa cggcgtaccg atctcgtcct ggcggcggta gcggcggccg
     5521 atcgcgcccg cgtcgtcgaa ctcgatgttc cagttctgcc ggagcgcctg ggcgaggccc
     5581 ttggccttcg gggagagctc cgggttccgg gagagcggga gcaccgcgac cttcaccggc
     5641 gccagacggt ggtcgaggcg cagcaccgtg cgcttctcca tcttgccctt ggcgttgggc
     5701 gcctcgtcct cgacgtaggc gtcgagcagg aaggcgagca tcgcgcggcc gacaccggcc
     5761 gcgggctcga tgacgtacgg cgtccagcgc tcgccggcct cctggtcgaa gtaggagagg
     5821 tcctggccgg aggccttgga gtgcgcgccg aggtcgtagt cggtgcggtt ggcgacaccc
     5881 tccagctcgc cccactcgtt gccgccgaac tggaagcggt actcgatgtc agcggtgcgc
     5941 ttggagtagt gggagagctt ctccttcggg tgctcgtacc accgcatgtt ctcctcgcgc
     6001 aggcccaggc cggtgtacca gttccagcgc tgctccatcc agtactcctg ccacttctcg
     6061 tcctcgcccg gcttgacgaa gaactccatc tccatctgct cgaactcacg ggtacggaag
     6121 atgaagttgc cgggcgtgat ctcgttgcgg aaggacttgc ccatctgcgc gatgccgaac
     6181 ggcggcttgc ggcgggaagt cgtctgcacc tgggcgaagt tggtgaagat gccctgggcg
     6241 gtctcggggc ggaggtaagc gatggagccg ctgtcctggg tcgggcccag gtgcgtcgac
     6301 aggaggcccg agaactgctt gggctcggtg aactggccct tgttgccgca gttcgggcag
     6361 ttcacatcgg cgaggccgtt ctccgggagg tggcccttct tcgcctcgta ggcctcctca
     6421 aggtggtccg cgcggaaccg cttgtggcag gaggtgcact cggtgagcgg gtccgtgaaa
     6481 gtggcgacgt ggccggaggc gacccacacc tcgggggcca ggatcacgga cgagtcgata
     6541 ccgaccacgt cctcgcgcga cgtcaccatg tagcgccacc actggcgctt caggttctcc
     6601 ttgagctcga cacccagcgg cccgtagtcc caggcggcgc gctggccgcc gtagatctca
     6661 ctgcagggga atacgaagcc acggcgcttg ctcaggctga cgatggtgtc gatcttgtcg
     6721 gcggccacgg tgctctcttc attacgacga cgggcagcga atgcttcagg gtaccggcga
     6781 gggctccccc tcaaccaaat cggtagccct ctgtggacgg ccgctcacgc ttgttgacaa
     6841 ccgtttccaa tttcgctgaa aatgactgtc atgaacgtac gacgaccaca catatccggg
     6901 atcgccctcg cggccgtcac cgcactcggt atcggcaccc tctccgcctg ctcctccgac
     6961 agcgccgccg cgggcaacac ggacaagttc gacgtcgtcg cgtcgttcta ccccatggcc
     7021 tttctcgccg aggagatcgg cggcgaccat gtgaaggtca ccagcctcac cgagcccggc
     7081 caggagccgc acgacctgga gatcagcgcc cagcagcgcg ctcagctgga ggaatccgac
     7141 gcagcgctct tcctcaaggg tctccagccc tccgtcgacg aggccgtcgg ccagtccggc
     7201 ctgaagacga agatcgacgc cgccacgctc accaagctgg aggaccacgg caacctcgag
     7261 gacagccatg agcacgaggg cgaggaggcg cactccgagg aagaggagga gcacgcccgc
     7321 gacccccaca tctggctgga cccggtgaag tacgccgagg tcgccaaggg cgtcggcgcg
     7381 gccttcgaga aggcggaccc cgaccacgcg gccgactaca agaagaacac cgacgcgctg
     7441 gtcaagaagc tcggcgagct caacaccgag ttcacggacg ggctcaagaa caccaagtcc
     7501 aaggtcttct tcaccaacca cgccgccttc ggctacctcg ccgagcgcta cggcctgacc
     7561 caggaggcca tctccggcct cgacccggag agcgagccca gcccggcccg gatcaaggag
     7621 ctccagcagg aggccaaggc cgacggcgtc accaccgtgt tctacgagac acttgtgtcc
     7681 gacaagaccg cgaagaccct cgccgacgac gccggcctga agacggacgt cctcgacccg
     7741 ctcgagggca tcaccgacaa gtccaagggc gacgactact tcgcggtcat gcaggccaac
     7801 ctcacggccc tgaagacggc tctgggagcc aagtgatcga ccccatggag gacggcatga
     7861 ccgagcccgt catctcactg cgcggcgtcc gcgccgagct gggctcgcgc cccgtcctgc
     7921 gcggcatcga cctcaccgtg ggccacggtg aggtcgtcgc cctgctcggc gccaacggct
     7981 cgggcaagtc gacggccgta cgcagcgtca tcggccaggt cccggtcagc gccggtgaga
     8041 tcgagctgtt cggcaccgcg cgggcccggt tccgcgactg gtcgcgggtg ggctacgtcc
     8101 cgcagcgcac gacggccgcg ggcggcgtgc ccgccacggt cggcgaggtc gtctcctcgg
     8161 gccgtctgtc ccgcacccgc ttcggcgtct tccgcaaggc cgaccacgcc gccgtacggc
     8221 atgccctgga gctggtgggc atggcggacc gcgtgaagga ctcggtcaac gccctctccg
     8281 gcggccagca ccagcgcgtc ctgatcgccc gtgccctggc ctccgagccc gagctgctga
     8341 tcatggacga gccgatggcg ggcgtggacc tggcgagcca ggaggtgctg gcgcgcacgc
     8401 tgcgggaaca ggtggcggcg ggcgcgacgg tcctcctcgt gctccatgaa ctcgggccgc
     8461 tggagccctt gatcgaccgc gcggtggtcc tgcgcgacgg ctgtgtactg cacgacggcc
     8521 cgcccccgaa ggcagtcggc cagcacgcac tccccggcca cgaccatgtc cacccccacg
     8581 cggctcacga cgccgagccg atccggacgg gactgctgag ctgatggact tcctgaacta
     8641 cgacttcatg cagcgggcgc tgctggcggc cgtactggtc ggcatcacgg ccccggcggt
     8701 gggcatctac ctggtccagc gccgccaggc gctgatgggc gacggaatcg gccatgtcgc
     8761 gatgaccggc gtcggtctcg gcttcctcct ctcctggtcg ccggtgtgga tggcgacgct
     8821 ggtgtcggtg ctcggcgcga tcgccatgga actgatccgc tggtacggca ggatgcgcgg
     8881 cgacctcgcg ctcgcgatgc tcttctacgg cggtatggcc ggcggcgtga tgttgatcaa
     8941 cctcgcgccg aacggctcga acgcgaacct gacctcgtat ctcttcggct cgctgtccac
     9001 ggtgagcgag tcggacgtga cggcgatcat cgtgctcgcc gcctttgtgg tgctggtcac
     9061 cctcggcctg cgccgccagc tgttcgcggt gagccaggac gaggagttcg cgagggtcac
     9121 gggcctcccg gtccgcgccc tgaacctgct gaccgcgatc acggcggcgg tgaccgtgac
     9181 ggtcgccatg cgcgtggtgg gcctgctcct ggtgagcgcg ctgatggtgg tgccggtggc
     9241 ggcggcgcag cagctgacgc ggagcttcgc ggcgacgttc gcgatcgcgg tggcgatcgg
     9301 tgtgacggtg acgatcggcg gcacggtcac gtcctactac caggacgtgc cgcccggcgc
     9361 gacgatcgtg ctgctgacga tcggcgcatt catcgcgctg accgcgctgg cgaccccgct
     9421 ggccaggcgc agggcccgcg ccctggcggc ggcccagcct tccaccgacc cggcggagtg
     9481 tgcgattccg gccagccggg ggacggacgg gaaggtgagc gtctgaccgc gctcagccgg
     9541 ggctggcaca atggcccggc aagtgcagac gtgaggaggc aaccggtgac caccgctgga
     9601 ccgcccgtga agggccgcgc gactcggcag cgggccgctg tggcggcggc cctcgacgag
     9661 gtcgacgagt tccgcagcgc gcaggagctc cacgacatgc tcaagcacaa gggcgattcg
     9721 gtcggcctca ccacggtcta ccgcaccctc cagaacctcg ccgacgcggg tgaggtcgac
     9781 gtcctgcgca cctccgacgg cgagtcggtg taccgccgtt gctcgaccgg cgagcaccac
     9841 caccacctgg tctgccgggt ctgcggcaag gcggtggagg tcgagggtcc ggccgtggag
     9901 aagtgggcgg acgcgatcgc ggccgagcac ggctatgtga acgtggcgca caccgtggag
     9961 atcttcggca catgcgcgga gtgcgccgcg cgctgagcgc ctagtgagag cgccgcgcgc
    10021 tctgctgtgc cagataccgc agccgagtgc gatgcggggt gtcgggaagt cggtgcagca
    10081 ggtcctgcgc ctgcccggca taggcgtcag cggccgaccg ggccagagcg agtgcgccgg
    10141 tctcctggag cagctcgcgc agctcgggaa aggccgcttc cgtgtcaggg gcgcgccata
    10201 cggcgtccag gcgggcccgt tcctcagctc ccgcgtgttc atgggcgagc agcaccggca
    10261 gagtgggccg gtgattgcgc agatcgctcg cggggtcctt gccgacgtcc tgcgcggagc
    10321 cgtcgtaggg cagcaggtcg tcgcggatct ggaacgccat cccgagggcc gtaccgaaac
    10381 cgtcgagcgc gtcggcgtgt tcgccaccac cgctcagttg cgccccgagc cggcaggaga
    10441 ggccgaagag taccgccgtc ttcaggcggg ccatctccag atagcgctcc tgtccgcagg
    10501 tcaggtcgtc ctcgatctcc agctccatgg ccacgccccg ggccatggct tccgcggtcg
    10561 cgctcactcc gtgccatgcc tcgttgacct gttccgcgct gatcccgcgc gtcaggcatt
    10621 ccgtcaggct ctgcatggcg gacatgtaca gggcgttggc ggcgagcagg gcgaagccct
    10681 gaccgaagcg gcgcggtgcg gtgtcccggc cccgtcgctg ctggtccccg tcgatgatgt
    10741 cgtcgtgcat caggctcgcc acatgggtca tctccatcgc gaccgcgacg ggcagcaccg
    10801 actccggtga tccgcccacg gaaccggcgc tctccaggac cagcaccggc ctgagcagtt
    10861 tgcccggcgg cagcagggcg tgctgctgga tacgggcgag agcgtcgtcg tcggctcccg
    10921 tgacgcgccg ggtgagctcg gcgcgggcgg cccggtgcgt gggccactgc cggatgtcct
    10981 gggcgacaga tgccgccgtg gtgatccccg cgtcctccgt gcacgtcggc gactgccgca
    11041 gcgtcagcag ggcgagccgt ttgagttccg ccttccggat gcgggggacg cggcgcagta
    11101 cggccggcag atcgctggtg acggcgtcga ggtgcgagcg gtagagggaa cccatcgcat
    11161 cgatcgcggc cccgccgtac gggggcagtc cggcggccag tttgtcgccg tacgtcagca
    11221 gttcgcgggc atgccgggcc gcccggccca gcgcctccag cacgcccggt gtcgcccggc
    11281 gttcgaggag ttcggcgcga tcagttccgc aggcgcgcag catctcgtcg gagatccccg
    11341 cccagccgcg ggccaggtcc tgggaaagat cgcggagatt gtccacccgg tccagtccct
    11401 cgccgaaggc catggccagc tcgtcgagca ccggatcatc gccatcatcg cctgaacaac
    11461 cgagcagggg aagggacatc cgcacggggg cgccggcgac gcctcgggcg aaggcggaca
    11521 gctcttcctc ggtggcgaag ccgtcgcggc ggccgatgtc gccgcgggtg gtctcgatga
    11581 gctcccgcac cggttgccgt ggcagcggga agcgggtgat ggcatgcacc agggccgcgc
    11641 ggacgggatg ctcggaggtt cccgcgccga tctcctccag cagcagtccg gtctcgtcgt
    11701 cgaagcgcgc cgggccggac ccgtcaccgt ccgccaggtc gtccacccac cggaccagcg
    11761 ctccgacggc tgccagcgcc gggcggtgcc gcgccggcag cagggcgccc ggcatggcca
    11821 tgccccggtc ggtcttcagg gccagctgga agcaggtgcg gtacgagttc cgcagcctgg
    11881 cgtccgtgat cccggaggcc gtgaggcaat cattgaactt gtcgatctcc cagcgcgcca
    11941 cgacgctgcc tttcttcttc tgagtacggg cccggggccc aggtaacggt catcgcgccg
    12001 cccgtggaga gcagcaggaa cccgaggaac agaccgccca ggttggccat gacgagactg
    12061 acgaacgcga tggccagggc gaggacgccg gggaggacgc accggtccgg agaccaccag
    12121 gcgaggacgc ccgccgtcag ggcagcgaca cacaccagcc accccgtcgc ccccgcgagc
    12181 ccggagaact ggaccagccc gagcccgccc caggtcgtcc acaccacctc gaccccaccc
    12241 gccatgatca gcagcccgcc ccagaacggc cgggaccggc gccatgccgt ccagctcacg
    12301 ggcagccgtc cccgtcgcgg ctcacgcccg cctggaatcc ccgcgcggac atggtggccg
    12361 cggtgtaggc gcgcggcttg atcgtgacct gcgacgcctt gaacgaaccg gccgtcagct
    12421 cgaacgggcg cgacggttcg gcttccaccg ccagcccggc gtccgccatg gacagacggg
    12481 aggcggacag gccggcggcc tcgatggtga agccggacgc gctcatggac tccatgccga
    12541 tgtgcaccat gaagcgcccg gcgagaggga cgcgcacggg agaggtcaga cagacacgct
    12601 cggctcggaa gtccttgaac agctccacga acgcggcgtc ggtcctgccg ccaggggctg
    12661 cgccgggggc cagggacaga ccggagacgg tgacgcggtc agcggtgatg gtgaccgggg
    12721 agcgcccggc catggacacc tcgatggcac ccgcgttccc gctggccagc agcgcgaagg
    12781 cggcgccgtt gaccgccgcc agaagaaccg cgcaatgtct ccgccggaca ccgccacgcc
    12841 actcgcccct catgaagccc cgcccttcga tccttgagct cacatcggat catcggcttg
    12901 gacaacagtc ggacttccca cgaggacacg gggtgggagc gggccacacg gttttcgccc
    12961 ccgccggcgg tcgctgaaat tcagcccctt aggggtgccc cctctggggg agtttgagga
    13021 gcggggtctg gggcggagcc ccaggacggg acgggtaggg gcggcggggg cgaaaaagga
    13081 ccctcgccgc acccggcagg gaccgtcagt cctcctcccg ccgcccttcc atcgccacca
    13141 gctcctcgtt cgggatcgcc ccaccgaacc gccggtcccg cgaggcgaac tcgacgcaag
    13201 cccgccacag atcacgccgg tcgaagtccg gccacagcac atcctggaag accatctcgg
    13261 cgtacgcgct ctgccacaac agatagttgg aggtgcgctg ctcgccgctc ggacgcagga
    13321 acaggtcgac gtccggcatg tccgggtagt acatgtactt ggcgaacgtc ttctcgttca
    13381 ccttcgaggg gtcgagccgc ccggccttca catcctccgc caacgcctgc gccgcatccg
    13441 cgatctcggc ccgcccgccg tagttcatgc agaagtacag cgtcagcttg tcgttgtcct
    13501 tggtctgctc ctgggcgatc tggagctcct tggcgaccga cttccacagc ttgggcatcc
    13561 gccccaccca ccgcacccgg atccccagct catcgagctg atcacgggtc ttgcggatga
    13621 agtcacggtt gaagttcatg aggaagcgca cctcgtccgg cgaccgcttc cagttctcgg
    13681 tggagaaggc gtacagcgag atcgccccga cgcccatctc gaccccgccc tgaaggacgt
    13741 cgagcacccg ctcggcaccg accttgtgcc cctcggtacg cggcagcccc cgctccttcg
    13801 cccaccgccc gttcccgtcc atgacgatcg ccacatgctt cgggatcagc tcacccggca
    13861 gcttcggcgc gcgagcaccg gacgggtgcg gctccggcgc cctgtactca cggcgccgac
    13921 gcccaaggaa cccactcaca gccatgtgcc tgtcgtctcc ctcatactca cgcttactcg
    13981 tgactcactt ttccacgtac cgaagcgacc gcagcccgcg ctccatgtgc cagtgcagat
    14041 aggcggacac cagcccactg ccctccctga catggcgcgg ctcgcaggag tccgccgtct
    14101 cccagtctcc cgtgagcagc gcgccgagga gttccaaggt ctgcggcgac ggtacgacgc
    14161 taccgggcac ccggcagtcg acacagaccg agcccccgga ggcgaccgag aagaagcggt
    14221 tcggtccggg catgccgcac ttcgcacagt cgctgaaggt gggggcgtag ccgttgacgg
    14281 cgagggagcg cagcaggaac gcgtcgagga cgaggtgggg cgcgtgctcg ccgcgggaga
    14341 gcgtccgcag ggctccgacc agcagcagat actgctgcac cgccggctcg ccctcatggt
    14401 cggtgaaccg ctcggcggtc tccagcatgg ccgtcccggc ggtgtaccgc gcgtagtccg
    14461 tgacgatccc gccgccgtac ggagcgatgg tctcgctctg cgtgcacagc ggcagcccgc
    14521 gcccgatcag ctcgctcccc cgcgcgaaga actgcacgtc gacatgggag aagggttcga
    14581 gccgggcacc gaacttggac ttcgtacgcc gcacaccccg cgccacggcc cggaccctgc
    14641 cgtgcccacg ggtgagcagc gtgatgatcc ggtccgcttc cccgagcttc tgggtgcgca
    14701 gcacgatgcc gtcgtcgcgg aacagactca tgggttcatt ctcgcgtacg gcgggggtca
    14761 gcgggggcgg tcggggtggc tgatgctgtc ccagggggcc agattccatg gactggcgcg
    14821 gttcccggcg tccagcagcg cccgcagatg ctcatcggcg accgcctgcg acgcgggcag
    14881 atccgactcc tccgcgtccc gcagcgccgc ccgccacacc tgccgcccga gcagataatg
    14941 accggcgtac tcctcccacg aggcatacgt ccgcaccacc gtcggcacga tgttcttcag
    15001 cgccgtccag gcgtcgccct cgtcgatcag cccgcaggcg aagccccggc gggcgatgtc
    15061 gacatacagg gcggcgtccc aggccagcgg cgagacgccg gtctgccggt acgcccgcgc
    15121 ccggtaacca ctgtgggcca gctcgtcgag ccgaccgacc agcccctcac gcgaggtgat
    15181 ctcccactgg tcggccaacc agcgccgggc gctgtcgtcg tcgatccgta catatgggta
    15241 cagcgtcgtc cgcgaggcgc tcttgtcccg gctcaccggc gcgctcagcg acaccatcca
    15301 cagctggtgc atggtgagcg gcacggggta gcggcgcgtc gccttcacac cgcgccgtct
    15361 ccatctccac aaagccatgc cgccgcaccc tacgcacccg cccctacgtc aaggaacctc
    15421 acccctgctt cgtgcgttcg cgtacgccgt cgccgcgcgc agccgctcgg cgggagtggc
    15481 cgtacgtacg gacgccggct cggcgtccca ctccttgccg ccgccgtaag gtctcagctg
    15541 gacatacggc ccttcatgcc ccatcacgac gccgatccga cccgaacgag tgtcgacgac
    15601 ataggccccg ataggcggct tcatcgcaac accgtcgcga gacgctgcgc ggtctcgacg
    15661 gaacaacggc ccaattcgac gagcgggcac ggggcttcac gcgcaagact cgccggatcg
    15721 atccggagtg tcggaagcgt aattcctgcc ttctccagtg ccgcccgcaa ttccttcact
    15781 gcatcctccg cttcttcgac gcagcgcgcc gagtgtcgtg ccgtcacctt gctcccctgt
    15841 cttttgggtt tcattctttc cacatccatg gtgacctgcg acgtctacac tcggcaggag
    15901 tctgtgcgct acaagtgcgg ggcagggtaa gggggttggg ttatggccaa cggttcgcgg
    15961 atggcggcgt gggagttctt cggcagcgag ctgaagaggc atagggagaa cgccgggatc
    16021 actcaggtgg agttgggggc gagagtattc gtctccggtg gttatatcgg ccagttcgaa
    16081 caggcaattc gaaagccgca actggatgta gcccagcgga ttgacgaggt tctacaaacc
    16141 gacggctttt tcgagcggac gtggcgacag ctcatcaacg acaagcggta cgccgactac
    16201 ttcgggccgg tcgtggagct ggagcggctg gccacgaaga tctgcgagta cgcacccacg
    16261 gtggtgccgg gcctgttgca gacggcagcg tacgcagagg ctgtcaccat cgcggccaac
    16321 cccttcgtca ccaacgcgta cgtcgaggag aaggtcatgg cccgcttgga acgagcggac
    16381 atcctcaagg acgctacaag gccggagtat tgggcgatcc tgcacgagaa cgtgctgcgc
    16441 atcccggtag gcggcccgga ggcgatggcc gagcaactgg agcacatcgc gcatctgatg
    16501 cgcgagcgca cggtgtggtt gacggtgatc ccgtacgcgg ttggagcaca cgcgtcgatg
    16561 atcggggacc ttcggctcat ggagttcgag gacgcccctc cggtcgccta tacagagacg
    16621 tcgttttcgg gaacgttgtt ggacgatccg gctgtggtga agcgggcgca gcgcgcatac
    16681 gatctgctca ggggcaccgc gctgtcgccg gaggcgtccc tggccctgat cgagtcggcg
    16741 gcggaggact tcagacgatg cgcgagtacg acctgagcag cgcgaactgg cgcaagagca
    16801 gccacagcaa cggcgagggc ggcaactgcc tcgaagtagc cgacggagtc cccggtgtca
    16861 tccccgtccg agactccaaa ctcgcctcgg acagccccgt actcctcatc cccgcccccg
    16921 cctgggaccg cttcctcacg tctctgcggt gaccctcggc gctggcgtcg tcgtgccctg
    16981 acgctccgcc tctgcccaca gctcggcgaa ctgggtctcg cggtcctcta tgtggtccgg
    17041 ctcggcgctg agcagggtgc tgtccggctt gttctcctgg tccggcttgg tctcgtggca
    17101 gagttcgccg tcgaagatga tgaagtcgtt cacgcggggg ttggactcca tcagcgaccg
    17161 caccgcgata cgcgcgtcga tgccgcgccg gcggtgccgc tcgcacagtg ctctgaggtc
    17221 gggcgtgacc tcctcctcgt cgaggacgac gaacacgcgc cggatctcca cgccccgccg
    17281 cttgatcgcc ttctcctgcg cgtcgaggta ccgttcgccg ggcccgctgg tccagaactc
    17341 ccggtccacc gaggtgctcg tggcgtcgag ggtcatcttg acgcagtcgg tgatgtcgat
    17401 cagccactcg tggttctcgc cggggcagtc cgcgttgccg ctgccgaggc cttccatcat
    17461 cttggcgagg cggccgagtt ccttctcggc gaaggcctgg acgatgtcgc cgccctgttc
    17521 gcggaccttg gtgtagccga ggacgagccg ggtcacctcg tcggagcgca gtacggaacc
    17581 gtcgacctgg ctgaacagcg tcgtcgcggc gaggatctcg ttgaagcggg tgtcgacctt
    17641 ctcgaaccgc tccccgaagt cgatcaggta ctgcacgatc agggcggcgc tgccgatgac
    17701 gatggacgcc acccactgcc agatgttgcc gtcgtcctca ctgaggatgc tggtgagcag
    17761 gaaggccccg cccgccgctc cggcggtgat cacgatccgc cagaacatct tgggcatacg
    17821 tggctcctgc cgcggtacca cttgcccgtt gccgcctgct cctaacgatg acgccccgct
    17881 catgtctcat cccccgtcgg gtatctgttt tccggctgcc gccgtcagct cgtgctgagc
    17941 gcctggtgcg gcatcgccac ggcctggagg gccagtcggt ctcggatgcg ccggctgagg
    18001 ttctcccact ggcgggagaa gcccggtttc tcttccagca cgtcccacag gtgacccagc
    18061 gcggggtcca cgtgtgcgcg cggcatccac agatgcagca gatgtacgac gaccggatgc
    18121 agcgcctcga ccacagaagg cccgtcggcc gtaccgagcc tgctgttgtc aagcatgtgc
    18181 tgaacagtcg tcaaaagcca gtcgtgcagg gcgagatcct cgcagaggcc cgccgcagcg
    18241 gcggccggga tgtgctcggg gagccgtagc tccatggtgc gcaggccgcc ctcggcgacc
    18301 gtgaagttca ccagcgaggc ctgctgatca ccacgccggg cgacccaacg cagcctcgtg
    18361 ggactggact tgaacggcac ccgccggtcc agcaacgcgt ggcgacggag tgcggccagc
    18421 aggccctcgg cgatcatccc caggtccagc tcaccgcgcc gcgcgcctcg caacatgcct
    18481 tccaccgtgg cctgttgggg cagcttgccg aagggttcca ccagacccgg acgtaccagg
    18541 tactggcccc aggggcggcg gatgtcgggc ccggcggcgg ggaggctgaa gtacgccgtc
    18601 gcctggagca gccttccctc ggtcagcgcc gcacgcgccg ccaccgtacc cacggacctg
    18661 accttggagc cgttggacgc gggcagccgg cagtccacac cggtgaggat ctcgggggac
    18721 agggcgtaca tgctgggccg ttcggagatc cgtacgggtt cgtcggcgcg cagccggagc
    18781 agctgggcgg cggcccgcgc gtcgaacgcc tggaaggacg gcagcagaca ggtgcgcacc
    18841 tcaccgcagg cgaggaccga acgcgcgggt tgtccgagag ccgccgtcat ctcaggtccc
    18901 ctcggcctcg gaggagtccg cgggctcctc gtagaagaca taggtggcgc gttgcgcgac
    18961 ggctgccggg accggcatac gttcggcggc ggatcgctcg gctacctgct ggagcgcccc
    19021 ggcgtccacg tctgtctggt cgaggatgag ccgtacggcg tcctcgacgg cgatgaagcg
    19081 gttcggcatc atgctgcacg tgcgataggc gctgaacgcc gccctggtgt cggtgagttt
    19141 gatcagcggg ggcagccggt cccagtcgtg cgggaagtcc gcgccgcccc actccctcgg
    19201 caccagcacg ggctcaccga ggtgccgtaa cagtccgagt ctggccagtt gccatacggc
    19261 ggccaggaac gggcaggacc acagccgccg cccgtccttc tcggaccaca gctcgacgtc
    19321 catgaagatg gagtggttgc gggccgcggt ctcctgtggt gactcccagc ccttgaccgc
    19381 gcccagcgcg ctgcgggacg ccgagggcgt acgttcgccg ttggcgagcc agccggtctg
    19441 cgagacgggt gggcgggagc cgtagctgcc gggcggcggg gattccacca gccggtgcat
    19501 gacggactcg gcgagctcga tcctgtccgc caccgcgcaa cccgactcac gcgccaggta
    19561 gtcgatgacc aggcccgcct tctcggcctc cttcagcacc atcgggatca gctcggccgg
    19621 ggtggagaag cgggtgaagt agtcgtcgat gagaaagcag gtgctgatgc gcgggcgctg
    19681 agtgcggcgc tccagggacg cgcgtaccgc gtccgcccag acccgtacct ccgcgaagtg
    19741 ctcacccagc ctcttggggc ccgcctcgaa gtcctccatg tagagatggc ccagttcgag
    19801 ggagagatgg gccagcggga cggcctgggt gcgcagctcc gctgtggtct cctggaaaac
    19861 ggcctcggtc acacctgctc ccagtacttg tcgtcggtca ggcgtccggc gagctggctc
    19921 agcgcctgcc aggtctcctg gttggcgatc tggctgtcga gcacgtcctc gtcggtgatg
    19981 agctgctcac gccattgcag gaccggttcg agcggtacgg agccgaggac ctggctgtag
    20041 ccgatgccgt gcgtggaggc gagctgcttg aggtcgccgt cggtcttgcg catccacgcc
    20101 gactgggtgg gagagacctg ggaccacagg ggtgactccg ggtcgggtac ggcggcccgg
    20161 acgaaccgga tcgagttgcg caatgcctcc tcgtcatggc cgcggtcggc gcctccggcg
    20221 aggatgccgc gcttgccgaa gaccaggctc gcggcggcgg cgacatgctg gcgggtccag
    20281 cggtggaaga ccagccagcg ggccgtgatc tcgcgcatct cggcctgtgc ggtcgcttcc
    20341 aggaccatgt cgacggcgta ggaacggccc gcgctgagat cgacgacgac caggtcgaac
    20401 tcgtagtaga gcgtcgtcag cagatcgacg cagcggcgca gattgtcgcc gctgatcgcg
    20461 aactcgccgc cgctgacatc gccgggcatc agcaccagcc ggccggagcc gggcggcggg
    20521 aagcgcagta cctggtgctc cgtctcggac cagacgtcga tccgggccgg ttcgctgacc
    20581 tcgcctatga ggtaggcgtg cagaccgcgg tcctcggtct gctggcgggc gtcggccacg
    20641 tcgaagacgg ccgccgcggt gggcgagccg aagtcgaagt ccaggtagca gacgtcgtcc
    20701 ccggccatcg cgcggtggta ggcgaggttg gcgctcgtga ccgagcggcc cgtgcctcct
    20761 ttgtcggagg cggcgaagat cagcaccgtg tcacactccc cggtccgcgg cttcgcgggc
    20821 acgggcgagc gagtcgagct gtcccagcac gtcgagcgtc aacgcgtagg ccgtacccgg
    20881 ctgttcatcc acgaggctgc gggcgcggcg caacttgacc tcgatgttcc tcagttccat
    20941 accgtgccgg ccggagtcgg agggcgcggg ttccatctgt tcgttgccca gcaggtgcgc
    21001 ggactcactg agcaacgccc ttgccagttc ggtgagttcg aggctgcgga tcgggggctg
    21061 gcggtacatg tcgtgggcct ggaccatcac ctcggtgact cgctcggtga tgctccagga
    21121 caccgggaca cggcgtttat ggatctccgc gtcgggatac gccgcgtgca cgttgtccca
    21181 gaggccgacg ccctcgccgt cgcggatccg gcgccgccac atatggtcga agatgtcctc
    21241 ggccagcctg agcagccggt cgtgcgaggc gaggttgcgg gagagggtgc acagctggac
    21301 ggtgcgcttc agcagctggg ccgagaagtc ggtcatggac caggtcatgg gcgggccgat
    21361 ccgctcgctg ccctgcagcg gcagcgcgac accgacattg tgcagctggt gcaccatcgg
    21421 gtcgtccttc gtcatacggc tggtgatacg gccgcgctcg gcgaggcgct ccatgatgcc
    21481 gacggtgcgg gtgaggtcgt cgtcggtggc ccggcggcgc atcaggtcgt gcacgaggat
    21541 ggcggcgacg gagagggaga agtactcgga ctccagcttc tgtcccgtcg tacgccaggg
    21601 gatgtcctcc aggggccagc gctcgtcgtc gaagcgggcg atgcgggacc agtactgctg
    21661 ggtcagctcc caccgcagcc ggagcgcctc ggcgagcctc tgctgttccg cgttgagcag
    21721 gccgagggtg agggtgcggt cggagaacag gtcctggata ccgtcgaggg cgaccaccgt
    21781 gaagtagaga tacggcaccg acttggcgac gccctggggc tgcggcccga tgggttcgct
    21841 ggtctcgacc tcgggggcgt cgtccaccat gctccaggcc cagccgcact cgaagagctg
    21901 gttctcgtcc ttgaggcctt cctggacgtc gataccgagg t
//
