LOCUS       NZ_BNBM01000002        43552 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces lanatus strain JCM 4588 sequence02, whole genome
            shotgun sequence.
ACCESSION   NZ_BNBM01000002
VERSION     NZ_BNBM01000002.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces lanatus
  ORGANISM  Streptomyces lanatus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 871820)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 61X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014655715.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 05:46:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,254
            CDSs (total)                      :: 9,172
            Genes (coding)                    :: 8,973
            CDSs (with protein)               :: 8,973
            Genes (RNA)                       :: 82
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 199
            CDSs (without protein)            :: 199
            Pseudo Genes (ambiguous residues) :: 0 of 199
            Pseudo Genes (frameshifted)       :: 83 of 199
            Pseudo Genes (incomplete)         :: 153 of 199
            Pseudo Genes (internal stop)      :: 16 of 199
            Pseudo Genes (multiple problems)  :: 50 of 199
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:57:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 107216
            Orig. end                         :: 150768
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BNBM01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..43552
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="False"
                     /product="NRPS-like"
                     /product="butyrolactone"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX) and not alpha_am_amid)"
                     /rules="AfsA"
                     /tool="antismash"
     cand_cluster    1..43552
                     /SMILES="NC(C(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /detection_rules="AfsA"
                     /kind="neighbouring"
                     /product="NRPS-like"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..43552
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:23552](-)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..23552)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     gene            389..1357
                     /locus_tag="IE325_RS05755"
                     /old_locus_tag="GCM10018780_11640"
     CDS             389..1357
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007381769.1"
                     /locus_tag="IE325_RS05755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11640"
                     /product="hypothetical protein"
                     /protein_id="WP_190068617.1"
                     /transl_table=11
                     /translation="MTDTTAPTPRRPGEQALAALGLGAPALDPSDASPHTFPGGGRWRT
                     EVPSVEGPEALAVVLKESSRLDVPIHRISQGSGIWMLSDAEITEMVEATAERDIELCLF
                     TGPRGTWDIGGSTRTDSKGGGLRARGHDAVAGCVEDAVRATELGVKCLLVADEGVLWTL
                     HRARVAGILPADTTLKVSALIGPVNPTAYAVYENLGGDSINVPSDLTLDHLTEIRRVSA
                     APMDMYIEAPDDLGGYIRMYEVAELIRRGAPLYLKFGLSKAPGIYPYGHHMRDLTLATA
                     KERVRRGRLALDLLARHGADGDMAPLGSRLPGTLTRFETPA"
     gene            1495..2607
                     /gene="chvE"
                     /locus_tag="IE325_RS05760"
                     /old_locus_tag="GCM10018780_11650"
     CDS             1495..2607
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /gene="chvE"
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019522547.1"
                     /locus_tag="IE325_RS05760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11650"
                     /product="multiple monosaccharide ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_350894211.1"
                     /transl_table=11
                     /translation="MRTRRAALAAIASAASLALTLSACGQSGEGGSKDEGGDTKGATIG
                     IAMPTKSSERWIADGNNVKKDLESKGYKTRLVYGEDDPDQQVSQIENLITQGVKALIVA
                     AIDNKSMNNVLQQAKDADIPVISYDRLILGTENVDYYASFDNEKVGELQANYIVEKLGL
                     KDGSKKGPFNIELFAGSNDDNNTRYFFGGAMKVLQPYIDKKQLVVRSGQTKLTQVTTLR
                     WDGGTAQKRMDDILTSAYKSERVDAVLSPYDGISIGILSALKSDDYGSKAKPLPVVTGQ
                     DAEVASVKSIIAAQQSMTVYKDTRELAKVASGMVDALLNDKKPEVNDTKTYDNGAKVVP
                     AFLLEPVAVDKTNYQKEVVDSGYIKASDLK"
     gene            2640..4190
                     /gene="mmsA"
                     /locus_tag="IE325_RS05765"
                     /old_locus_tag="GCM10018780_11660"
     CDS             2640..4190
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /gene="mmsA"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010042358.1"
                     /locus_tag="IE325_RS05765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11660"
                     /product="multiple monosaccharide ABC transporter
                     ATP-binding protein"
                     /protein_id="WP_190068619.1"
                     /transl_table=11
                     /translation="MAGPVLEMRSIVKTFPGVKALSDVTLTVQQGEVHAICGENGAGKS
                     TLMKVLSGVHPHGTYEGDILFEGEVCEFKDIRASEQRGIVIIHQELALSPFLSLAENIF
                     LGNEHAKGGFIDWRETLRHATELLRRVGLTDHPDTRVADIGVGKQQLVEIAKALSKKVK
                     LLILDEPTAALNDEDSGKLLDLIRELKKQGITSIIISHKLNEIRKVADSVTILRDGKTI
                     ETLDVKAPETTEDRIISGMVGRDLEHRFPDRTPHEPEEGAAPALEIRNWTVHHPIDQQR
                     KVVDDVSIQVRRGEIVGIAGLMGAGRTELAMSIFGRTYGRYHGGTVLKDGTEIRTKTVP
                     EAVRNGIAYVTEDRKHYGLNLIDTINRNISLSALGKVAKRGVVDEHEERQVAEGFRKSM
                     NIKAPTVFEPVGKLSGGNQQKVVLSKWIFAGPDVLILDEPTRGIDVGAKYEIYTVIDQL
                     AAQGKAVVFISSELPELLGMCDRIYTMAAGRLTGEFSRAEASQESLMRQMTKDKEVTR"
     gene            4187..5431
                     /gene="mmsB"
                     /locus_tag="IE325_RS05770"
                     /old_locus_tag="GCM10018780_11670"
     CDS             4187..5431
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="mmsB"
                     /gene_functions="transport (smcogs) SMCOG1113:
                     inner-membrane translocator"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015577044.1"
                     /locus_tag="IE325_RS05770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11670"
                     /product="multiple monosaccharide ABC transporter permease"
                     /protein_id="WP_190068620.1"
                     /transl_table=11
                     /translation="MSTDVTAKTPAPAPPGKSGGAAGDGLLQLVLDGMRRNMRQYGMLI
                     ALGLIVALFAVWTDGDLLLPRNVSNLVLQNSYILILAIGMMLVIIAGHIDLSVGSLTAF
                     IGSMAAVFMVKNDLPWPVAVILCLAMGAVAGAAQGFFIAYGGIPSFIVTLAGMLIFRGL
                     TEIFLEGQTLGPFPEGLQKVANGFMPEVGPNTNYHNLTLLLGFGMIAFVVFQEFRDRRR
                     QQEFHLDVPPFNLFLLKLVALGAAILTLTMLLASYKGAPIVLLILGVLLVGFGYVMRNA
                     IIGRHIYAIGGNLPAAKLSGVKDKKVTFLIFMNMGMLAALAGLVFAARFNAASPKAGLN
                     FELEAIAASFIGGASMSGGVGTVLGAIIGGLVLGVLNNGMNLVGIGTDWQQVIKGLVLL
                     AAVGFDVWNKRKVGS"
     gene            5543..6691
                     /locus_tag="IE325_RS05775"
                     /old_locus_tag="GCM10018780_11680"
     CDS             5543..6691
                     /EC_number="5.1.3.-"
                     /GO_function="GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA]"
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003989972.1"
                     /locus_tag="IE325_RS05775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11680"
                     /product="aldose epimerase family protein"
                     /protein_id="WP_190068621.1"
                     /transl_table=11
                     /translation="MDMRRRTVIAGAAAAGITAATVGSASAHATGGRTPVKSLFGKLAD
                     GTEVYSWSLANGGTRMKVLSYGGVQSLEVPDRRGRYANISLGFDNIEDYVAKSPYFGAL
                     IGRYGNRIGKGKFTLDGKAYQVNVNDGENSLHGGAKGFDKRVWDVEPFTKGTDVGLRLY
                     YTSVDGEMGYPGTLKVKVTYTLTRHGDWRIDYEATTDKATVVNLTSHVYWNLAGEGSGT
                     IENHQLKIDASRYTPVDSGLIPTGELARVAGTPFDFRRTKAIGEDLREPHQQLLYGKGI
                     DHNWVLDKGISPRPEWIATLKDPSSGRTLRMATTEPGLQFYSGNFLDGTLVGSGGNVYR
                     QGDALCLETQHFPDSPNKPSFPSTVLRPGQTYRSTTVHSFTC"
     gene            6864..8468
                     /locus_tag="IE325_RS05780"
                     /old_locus_tag="GCM10018780_11690"
     CDS             6864..8468
                     /EC_number="2.6.1.9"
                     /GO_function="GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (73-361). E-value: 1e-28.
                     Score: 92.4. Matches aSDomain:
                     nrpspksdomains_IE325_RS05780_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010042354.1"
                     /locus_tag="IE325_RS05780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11690"
                     /product="histidinol-phosphate transaminase"
                     /protein_id="WP_190068622.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.3e-27, bitscore:
                     92.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNVTSLFRSTAAHSPSMAALTREGGDGAGPVDFCIPCNPYFPT
                     PEMFQDMGARLRDIITYYPSSADTITAELCSLLQLPPQCVAMGNGSTELITWIDHLMVR
                     ESLAIPVPTFGRWTDQPMETGKRVDMFPLQESSGFALDLAQYAEFIRARGTRVAVICNP
                     NNPDGGFLHKHALVQFMDAMADLDLVIIDESFLEFADAEQEPSVVQEAMLRPNVIVLRS
                     LGKNFGLHGIRFGYLVANPALAGMVRSMLPKWNLNAFAEHVVFMLKNHGAEYAQSLHQV
                     RRDRLDMASHLAQLPGLTVYPSQGNFLFVRLPVGAEGTVVRDRLLTEHRILVRECGNKI
                     GSSSRFLRLVVRPQVDVRRLVSGLEQVLYGTRRGAAVPELGTGTNYSSGTAAVDRLVSS
                     TNGAGVAGLAAQAMAAPQPQAVPQAVPQAVPQGGGMPMPAPMPVAPMPTPVPAPAPMPA
                     PAPVAPAPMPFPSPVAPAAAVVPPPAAGPTPPGVPARGGLTAAQVRGTTGPGLTPAPAT
                     GWPNAQSWPNAAGMQAG"
     misc_feature    complement(6865..6879)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.18"
                     /tool="antismash"
     aSDomain        7083..7946
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS05780_Aminotran_1_2.1"
                     /evalue="1.00E-28"
                     /label="IE325_RS05780_Aminotran_1_2.1"
                     /locus_tag="IE325_RS05780"
                     /protein_end="361"
                     /protein_start="73"
                     /score="92.4"
                     /tool="antismash"
                     /translation="LCSLLQLPPQCVAMGNGSTELITWIDHLMVRESLAIPVPTFGRWT
                     DQPMETGKRVDMFPLQESSGFALDLAQYAEFIRARGTRVAVICNPNNPDGGFLHKHALV
                     QFMDAMADLDLVIIDESFLEFADAEQEPSVVQEAMLRPNVIVLRSLGKNFGLHGIRFGY
                     LVANPALAGMVRSMLPKWNLNAFAEHVVFMLKNHGAEYAQSLHQVRRDRLDMASHLAQL
                     PGLTVYPSQGNFLFVRLPVGAEGTVVRDRLLTEHRILVRECGNKIGSSSRFLRLVVRPQ
                     VDVRRLV"
     gene            complement(8487..9917)
                     /locus_tag="IE325_RS05785"
                     /old_locus_tag="GCM10018780_11700"
     CDS             complement(8487..9917)
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004001541.1"
                     /locus_tag="IE325_RS05785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11700"
                     /product="family 43 glycosylhydrolase"
                     /protein_id="WP_190068623.1"
                     /transl_table=11
                     /translation="MARRLLTLLAALLLALSIGQPSASAASFTNPVKVQKGADPWISYH
                     DGNYYLVTTSWTDVITMRKAPTLAGLASAPSVQVWKGDAANRCCNIWAPELHFLNGRWY
                     LYYVAGQNVSDYNPTQRTHVLESAGSDPMGPYTYKNQLNSAWMLDPNVATINGQLYLFG
                     SASGGTQNLVAARMSNPYTLATGFSTISTPTYDWERNGTVNEGPEILQRGGRTFLIYSG
                     SGCWTPDYKLGQLTLTGSDPLSAASWTKKSTPVFQRSDANGVYGPGHNGFFTSPDGTEN
                     WIVYHANDSASDGCDNGRTARAQKFTWNSDGTPNFGTPVRLGAALTGPSGEPSSSSSNY
                     TITNRNSGKCLDVAGSSTADGANVQQWSCSGGNNQKWRLEDLGDDTHRLVNVATGKVLD
                     TENCSSADGADLRQWSWLDNTCQRFRFVATDGGFVRIVNQATGKVADVANCGTADGADV
                     RQWSWLGNNCQQWRLNPA"
     gene            complement(9899..10867)
                     /locus_tag="IE325_RS05790"
                     /old_locus_tag="GCM10018780_11710"
     CDS             complement(9899..10867)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003976379.1"
                     /locus_tag="IE325_RS05790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11710"
                     /product="arabinan endo-1,5-alpha-L-arabinosidase"
                     /protein_id="WP_190068624.1"
                     /transl_table=11
                     /translation="MSRKRTTLLALPLATLLALTPTSASAYPNPGRVTGDIVTHDPTMI
                     RTSSGQYLLYATGGGIANKVSADRTAFRNGADAFSGRPGWWSTYSSVPEAWAPDISFRG
                     GKYLMYYSVSKFGSNTSAIGLAGSTTGQPGSWTDYGTVYTSSSSSDYNAIDPNLFVDDD
                     GKWWLSFGSWWTGIKMIQINPSTGKQLSSNTTRYSLASRPTGTKAVEAPYIVKRGGYYY
                     LFASYDTCCAGTSSTYKVKVGRATSITGPYRDKNGVSMMSNGGTPVLESHGSVIGPGGQ
                     SIMNDADGDLIVYHYYDGNDNGTPKLGINLLNWSSGWPVAY"
     misc_feature    11051..11064
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.8"
                     /tool="antismash"
     gene            11164..11793
                     /locus_tag="IE325_RS05795"
                     /old_locus_tag="GCM10018780_11720"
     CDS             11164..11793
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018542521.1"
                     /locus_tag="IE325_RS05795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11720"
                     /product="SUKH-4 family immunity protein"
                     /protein_id="WP_190068625.1"
                     /transl_table=11
                     /translation="MPQLVNRGMMESAFPPKKVVRVREDGLPACLHESAHVILTDVGLP
                     DDRASFFAIDGALFEGETPNSFRRCAELSYFSAYKNMPNGWENWLVIGEIFYDCVVLDP
                     VSGIVYCLPDGEYRADPLNQSLDSFVYFVYLLELERPNYDFTVSDEIPDSEGVAVFLRE
                     RMIRVDPLPFEGVEPSWSEVFDWEAEDAPRMPAWDVVLSNVYESIG"
     gene            11806..12537
                     /locus_tag="IE325_RS05800"
                     /old_locus_tag="GCM10018780_11730"
     CDS             11806..12537
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025791.5"
                     /locus_tag="IE325_RS05800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11730"
                     /product="nucleic acid/nucleotide deaminase
                     domain-containing protein"
                     /protein_id="WP_190068626.1"
                     /transl_table=11
                     /translation="MAVPYFVTAESDPVPLEDFAKSVGRAVVREECREWARLGGDRGFE
                     ICADHDGVVRAVLLDWDEDLRFVSSAPEAFVESLAALDRALAVILGTDSPQEAAAAYGE
                     LERRLQVIDPQAFAGRENWWPLVLDDIRDTAGAEWFTAFEIVDERGEKQIVTQAGGIGV
                     HPEERLWGRLRAAGVAAEQVLRIHTELEACFMPGHYCSLWLGQVFPDAQLTHNFPYGET
                     AESRAEGIRLLREAAEQAPSQ"
     gene            12576..14339
                     /locus_tag="IE325_RS05805"
                     /old_locus_tag="GCM10018780_11740"
     CDS             12576..14339
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020138863.1"
                     /locus_tag="IE325_RS05805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11740"
                     /product="hypothetical protein"
                     /protein_id="WP_190068627.1"
                     /transl_table=11
                     /translation="MTVGAAVPDISSWPPLDDDKRAFGQQLLGWAADGSGAGHRLCLVR
                     GAEGSGKSHLLAWFLAGAAGSPRTTVHATILAEGLTADTFAWELGRQLGYGPLSPARLL
                     DRVSQDERPLLLLVVDLHRSGAGPADLPTAAPATLVAALLEPLLALPHVRAAVEIGDDD
                     HGLLSADGADIIDLGGDGGRGSAGEMSFAELAATVPRTADGRPDWSRAPAPSLRHILDA
                     ALRADDEGAAVRGLLADPGFLVHGSANALTATLADERIPVPGRLREVWQRAAPELTAHH
                     DDSAERAALLHAAAVGTDAALSEFLRPLARRHWWSAVWARPDLPVAALAPAPGDEPRLL
                     TADVTGRIRTYDTGTGAAAGATGSPPSTRPVAVAPRDAHAMLLLDQTGVLLPLAPEDDP
                     IAGFMLDHIAEHHGAAALADDGAQVIALGGGSPQSPYAIVGDRGGNLHAWSLSDYQDSP
                     LSCRVHELPVTAAVCLRIPADDLTITFSAALDGSVRLWETSGEPMPVPVEQRASQVTAL
                     AAADTSVGPVLAVAWSDAELHLWHVLSGRMRALPLLHGCGSLALTPEGLVLVGGPEGLY
                     AARLRLDGLWP"
     gene            14377..14502
                     /locus_tag="IE325_RS45975"
     CDS             14377..14502
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016070.5"
                     /locus_tag="IE325_RS45975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_229911674.1"
                     /transl_table=11
                     /translation="MRRLSPEDPGIIVVRDSKAPEKRRLAVSPEAWGAFVSHASR"
     gene            complement(<14579..15493)
                     /locus_tag="IE325_RS46825"
                     /old_locus_tag="GCM10018780_11750"
                     /pseudo=""
     CDS             complement(<14579..15493)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013209.5"
                     /locus_tag="IE325_RS46825"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11750"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MHRTGMAHMPVRIHLTDDDLANIRLAQAPDPMWEALLSMHMLQTT
                     TGSAVFGAWRRTVCHQLSLDVGQLLRLAPPLGYSADFLTPAAGADGLDAGIDAVLSTPR
                     RRLRGDLAELSRTGRPLPLRARQLADGDKETVTYLAGTLRRYFATALAPWWPRIRSRFD
                     AERSVHGRYLVDGGLGSLLGSLHPGLLWHRPVLEVTGLGADRDVHLDGRGLLVLPSYFC
                     WRKPTLLKDPALPCVVVYPMTHETALGDREPEARSLNALLGRTRAVILESLAARGVTTT
                     ELAHGTGVSLATASHHVGVLRKAG"
     gene            complement(15551..16888)
                     /locus_tag="IE325_RS05815"
                     /old_locus_tag="GCM10018780_11760"
     CDS             complement(15551..16888)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1173: WD-40
                     repeat-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE325_RS05815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10018780_11760"
                     /product="WD40 repeat domain-containing protein"
                     /protein_id="WP_190068629.1"
                     /transl_table=11
                     /translation="MKLPNPFRRRRPTAPPKRPDPGSTARPNGEYELRGHSSIVMHLAT
                     VPTADGELLASGDTQGAVLLWDAATGEHVAGPVTVDSANVRGLAAVDLGTDGWALVCAG
                     ADGVTLWDPRDMSSPEYTPRRLVDTGASAVAVVPGEPQLLVVADGKAVRVIDPAGGQEV
                     FGFRQPPHPKGHIGDQVRRLVGVRPDDDTGGFAAARYGGGLEVWAPGRRGWHQGRFSLM
                     ARGPGDFTAYGSHLAIPAGRGIDVWDLRTGEHTARGELDTPYEVLAPVPLGGRTVIAAA
                     FRVYDECGVQLWDPHHPTALTPPFNRHGQAFGDASFGSATINDVIGITCPDGTTRVASA
                     GNDGCVLLSASLTEDDLVPGQRPGPAPVEHDNGNYARVRTRDGEIVGLWFADTARARDR
                     GLIEALLFREDLGHLLGTEHRVVPNTVDDKGGAFVMFGHHRAPGAP"
     gene            17023..17796
                     /locus_tag="IE325_RS05820"
                     /old_locus_tag="GCM10018780_11770"
     CDS             17023..17796
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126965.1"
                     /locus_tag="IE325_RS05820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11770"
                     /product="intradiol ring-cleavage dioxygenase"
                     /protein_id="WP_190068630.1"
                     /transl_table=11
                     /translation="MTDTSRGTSENTEKETPFTIGRRTVLIATGATAAALTVGAAAPET
                     PAAAQAAAAVCTLTKEMTEGPYYLDGQLVRADISEDKTGIPLELTLTVVDDDTCAPLDN
                     ALVEIWHCDALGEYSGFVGNNGHDEPDNGTFLRGGVLTGSDGVARITTVYPGWYRGRCV
                     HIHVKVHTDVTLTDDGSFTGGQELHTGQLFFDETITTRVAALATYAANTVPRTTLAQDG
                     IYDDGGAASGLLTLTALGSTPSAGYAGTLTLGVES"
     gene            complement(17854..18516)
                     /locus_tag="IE325_RS05825"
                     /old_locus_tag="GCM10018780_11780"
     CDS             complement(17854..18516)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015660647.1"
                     /locus_tag="IE325_RS05825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11780"
                     /product="DUF4360 domain-containing protein"
                     /protein_id="WP_190069197.1"
                     /transl_table=11
                     /translation="MARGLVRVLLSGGALAALLTTALPAQASPAFEDPPPDKIVIKVAT
                     VNGSGCPAGTTAVAVSEDNTAFTVTYSDYLAQVGGNSDPTAFRKNCQLSLVVHVPGGFT
                     YAIASADYRGFAALQPGAKATQKASYYFQGSPDTQSRNHAFSGPLNDNWQATDETDWAQ
                     LIWAPCGKQRNFNINTELRVNLGTSSASKVSFMTMDSTDGDISTVYHLAWKECPGAK"
     gene            18777..19244
                     /locus_tag="IE325_RS05830"
                     /old_locus_tag="GCM10018780_11790"
     CDS             18777..19244
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE325_RS05830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10018780_11790"
                     /product="hypothetical protein"
                     /protein_id="WP_229911675.1"
                     /transl_table=11
                     /translation="MTGNQEHDGRRGGRPGLGRHDDNSHEEEDNGTSLRGGRMTDESGQ
                     CDITSIWPGHYVSRAVHVHMRVHTDVTLTGDSYTGGEIIHTGQLFFDPDISTEVQTTSP
                     YAKNTTPETRLEDDGIYDDSGASSGLLTLAALGHSVSDGYKATLTVGVTSD"
     gene            complement(19258..19887)
                     /locus_tag="IE325_RS05835"
                     /old_locus_tag="GCM10018780_11800"
     CDS             complement(19258..19887)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003988493.1"
                     /locus_tag="IE325_RS05835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11800"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_190068631.1"
                     /transl_table=11
                     /translation="MARQERAIRTRESILEAMAGLFIEVGYEAATIAALVERTGLTRGA
                     LYFHFPTKEAMARGVLDGAVTREGILPQTYKLQEWVDLGLLLAHRMPQEPMLRAAVQLS
                     VDPKARSMFGTRWPDWINLGEDLLVEAEQRGELLPHAVPAEIARLAVGAWTGVQLVTEA
                     RPQGPGLDEEIARLYQLILPNVASVGVLAKLDTSPHRAKRLLGPAS"
     gene            complement(20001..23552)
                     /gene="car"
                     /locus_tag="IE325_RS05840"
                     /old_locus_tag="GCM10018780_11810"
     CDS             complement(20001..23552)
                     /EC_number="1.2.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /GO_function="GO:0031177 - phosphopantetheine binding
                     [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_process="GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: AMP-binding (78-515). E-value: 4.4e-69.
                     Score: 224.9. Matches aSDomain:
                     nrpspksdomains_IE325_RS05840_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (670-725). E-value: 1.9e-13.
                     Score: 42.5. Matches aSDomain:
                     nrpspksdomains_IE325_RS05840_PP-binding.1"
                     /NRPS_PKS="Domain: TD (780-1043). E-value: 2.2e-68. Score:
                     222.1. Matches aSDomain: nrpspksdomains_IE325_RS05840_TD.1"
                     /codon_start=1
                     /gene="car"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: NAD_binding_4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358814.1"
                     /locus_tag="IE325_RS05840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11810"
                     /product="carboxylic acid reductase"
                     /protein_id="WP_308437626.1"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-65, bitscore:
                     217.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8.7e-12, bitscore:
                     40.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 2.3e-55, bitscore:
                     182.9, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRQPEPVGDLTDRRPIPQGSRPLCLPSGDELEHATRRLRMRLAQ
                     LVASVMERHADRPAVGERAKEFARDSATGRVSIRLLPRYETTTYRELWTRVRAVAGEWH
                     HRPDHPLRPGERVAVLGFTSRDWATVDLACIHLGAVTVPLQTSAAPAQLRAIMAETEPF
                     VVAASLERLDAAVDLIRDSDSVRRLVVFDFHPEADDHRETLAAALDRLTEARPAVVVDI
                     LRDLIERGAALPEAPLFTAADGEDPLAMLIYTSGSTGTPKGAMYTERLAGAMWGGAWAK
                     LFDESYAVTFHYMPMSHVAGHSSLKATMVRGGASYFTAGSDLSTFFEDIALARPTELSL
                     VPRVCEMLHQRFRSEVERRTAAGTDRAEAEAEVRADIRENVLGGRVTWASSGSAPLSTE
                     LTAFIESLLGLDLHIVYGSTEAAGVSVDGVLLRPPVTDYKLADVPELGYFRTDLPHPRG
                     ELLLRSDAVVPGYYRQPELSAELFDEDGYYRTGDIVAELEPDRIAILARRGNVLKLSQG
                     EFVAPSRLEAVFAASPLVRQIFVHGDSERSYLLAVVVPTPDALRESDGDERALKQRLSG
                     TLQELAKETGLNSYEIPRDFLIETEPFSQANGLLSDHRKLLWPRLAERYGERLDALYAD
                     TTAREDEELAAIRLSGADRPVLETVQRAARALLAGSMADIGPDAHFRDLGGDSLSAVSF
                     SNLLQDTFGVRVPVDMVISPAYDLRHLAEHIEARRGTTERRPTFASVHGEGATEVHAKD
                     LTLDRFIDARLLTDAQALPRPQGEPRTVLLTGASGYLGRFLALEWLRTLAPAGGRLIAL
                     VRGKDDAAARRRLDAAFDSGDPELVRTYQELAADHLDVVAGDMAEPRLGLDEASWDRLA
                     DEVDLIVHAGALVNHVLPYPHLFEANVVGTAELVQLALTSRMKPVTYISSVAVATARPG
                     QPALDEDTDPRLAMPVQDVDGGYAGGYATSKWAGEVLLREAHDLCGLPVTTFRSNMILA
                     HSRYGGQLNVPDMFSRLLFSVLATGIAPRTFYRADGEKAHYDGLPVDFTAAAVVALGGR
                     GAPRHPSEYRTFGLVNPNDDGVSLDTFVDWLVQEGHPIERVADHADWYVRFEAAMRALP
                     EALRQYTALPILHGFKEPEEAVPGSVIPSERFRAAVRADGADGHGDIPSLTRDLVVKYA
                     RDLKSLMASAAGTGSGH"
     aSDomain        complement(20424..21212)
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS05840_TD.1"
                     /evalue="2.20E-68"
                     /label="IE325_RS05840_TD.1"
                     /locus_tag="IE325_RS05840"
                     /protein_end="1043"
                     /protein_start="780"
                     /score="222.1"
                     /tool="antismash"
                     /translation="VLLTGASGYLGRFLALEWLRTLAPAGGRLIALVRGKDDAAARRRL
                     DAAFDSGDPELVRTYQELAADHLDVVAGDMAEPRLGLDEASWDRLADEVDLIVHAGALV
                     NHVLPYPHLFEANVVGTAELVQLALTSRMKPVTYISSVAVATARPGQPALDEDTDPRLA
                     MPVQDVDGGYAGGYATSKWAGEVLLREAHDLCGLPVTTFRSNMILAHSRYGGQLNVPDM
                     FSRLLFSVLATGIAPRTFYRADGEKAHYDGLPVDFTAAAVV"
     aSModule        complement(20424..23318)
                     /complete
                     /domains="nrpspksdomains_IE325_RS05840_AMP-binding.1"
                     /domains="nrpspksdomains_IE325_RS05840_PP-binding.1"
                     /domains="nrpspksdomains_IE325_RS05840_TD.1"
                     /final_module
                     /locus_tags="IE325_RS05840"
                     /monomer_pairings="Val -> Val"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(21378..21542)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS05840_PP-binding.1"
                     /evalue="1.90E-13"
                     /label="IE325_RS05840_PP-binding.1"
                     /locus_tag="IE325_RS05840"
                     /protein_end="725"
                     /protein_start="670"
                     /score="42.5"
                     /tool="antismash"
                     /translation="SMADIGPDAHFRDLGGDSLSAVSFSNLLQDTFGVRVPVDMVISPA
                     YDLRHLAEHI"
     aSDomain        complement(22008..23318)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS05840_AMP-binding.1"
                     /evalue="4.40E-69"
                     /label="IE325_RS05840_AMP-binding.1"
                     /locus_tag="IE325_RS05840"
                     /protein_end="515"
                     /protein_start="78"
                     /score="224.9"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="RLLPRYETTTYRELWTRVRAVAGEWHHRPDHPLRPGERVAVLGFT
                     SRDWATVDLACIHLGAVTVPLQTSAAPAQLRAIMAETEPFVVAASLERLDAAVDLIRDS
                     DSVRRLVVFDFHPEADDHRETLAAALDRLTEARPAVVVDILRDLIERGAALPEAPLFTA
                     ADGEDPLAMLIYTSGSTGTPKGAMYTERLAGAMWGGAWAKLFDESYAVTFHYMPMSHVA
                     GHSSLKATMVRGGASYFTAGSDLSTFFEDIALARPTELSLVPRVCEMLHQRFRSEVERR
                     TAAGTDRAEAEAEVRADIRENVLGGRVTWASSGSAPLSTELTAFIESLLGLDLHIVYGS
                     TEAAGVSVDGVLLRPPVTDYKLADVPELGYFRTDLPHPRGELLLRSDAVVPGYYRQPEL
                     SAELFDEDGYYRTGDIVAELEPDRIAILARRGNVLKLS"
     CDS_motif       complement(22107..22181)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS05840_0002"
                     /evalue="7.00E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="IE325_RS05840"
                     /protein_end="482"
                     /protein_start="457"
                     /score="15.3"
                     /tool="antismash"
                     /translation="GELLLRSDAVVPGYYRQPELSAELF"
     CDS_motif       complement(22755..22808)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS05840_0001"
                     /evalue="3.10E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="IE325_RS05840"
                     /protein_end="266"
                     /protein_start="248"
                     /score="22.8"
                     /tool="antismash"
                     /translation="AMLIYTSGSTGTPKGAMY"
     cand_cluster    22955..33842
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    22955..33842
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[27954:28842](-)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(27955..28842)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="2"
     misc_feature    23580..23593
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.92"
                     /tool="antismash"
     gene            23701..24441
                     /locus_tag="IE325_RS05845"
                     /old_locus_tag="GCM10018780_11820"
     CDS             23701..24441
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018891168.1"
                     /locus_tag="IE325_RS05845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11820"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_190069200.1"
                     /transl_table=11
                     /translation="MQDRAARTRRDLIRSAAELIEQGGFAGASVGQICALAGVSRGALH
                     FHFGNKQALGEAVESTAAEILLCVTGQVPERHPAPLQFLVDTSHTLAQRVVCDPVLRAG
                     FTLAHDAAWHSDVSLWQHWRQWVRGLLDLARRQGSLARDVDLDGAVSAITALMAGLEGL
                     ERDPARDRIARSVTPFWRLVLPQLAAEAVRGRIEAAGSSAAMADEPPLERWRLDDGAAP
                     HECAAMSDAELCCVPYREMSGSAS"
     gene            complement(24411..25205)
                     /locus_tag="IE325_RS05850"
                     /old_locus_tag="GCM10018780_11830"
     CDS             complement(24411..25205)
                     /NRPS_PKS="Domain: Aminotran_4 (38-244). E-value: 8.4e-24.
                     Score: 76.5. Matches aSDomain:
                     nrpspksdomains_IE325_RS05850_Aminotran_4.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006348746.1"
                     /locus_tag="IE325_RS05850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11830"
                     /product="aminotransferase class IV family protein"
                     /protein_id="WP_190069199.1"
                     /transl_table=11
                     /translation="MNTRRNDRTAGVADLAPLAFAGYAHFTAMQIRAGRVRGLDLHLAR
                     LRHASLELFGRALPDDRVRTWLRAALDDAPADLSLTATVYSPSGEFTVAGPDEDPELLV
                     RGAPPATGPAGPLTLAVVEHERFLPSVKHVGEPAKTYFPRQAVQQGCDDVAFTDRRGRL
                     SEASIWNLAFWDGTAVVWPAAGMLAGVTMGVVRRQLDRLGVPQRVREVTPADLPALAGG
                     AVMNSWTPGVEVRRIGPTSLPEAPAFLDLLHRAYEAEPLISL"
     aSDomain        complement(24474..25091)
                     /aSDomain="Aminotran_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS05850_Aminotran_4.1"
                     /evalue="8.40E-24"
                     /label="IE325_RS05850_Aminotran_4.1"
                     /locus_tag="IE325_RS05850"
                     /protein_end="244"
                     /protein_start="38"
                     /score="76.5"
                     /tool="antismash"
                     /translation="LDLHLARLRHASLELFGRALPDDRVRTWLRAALDDAPADLSLTAT
                     VYSPSGEFTVAGPDEDPELLVRGAPPATGPAGPLTLAVVEHERFLPSVKHVGEPAKTYF
                     PRQAVQQGCDDVAFTDRRGRLSEASIWNLAFWDGTAVVWPAAGMLAGVTMGVVRRQLDR
                     LGVPQRVREVTPADLPALAGGAVMNSWTPGVEVRRIGPTSLPE"
     misc_feature    complement(25286..25299)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.51"
                     /tool="antismash"
     gene            complement(25290..25916)
                     /locus_tag="IE325_RS05855"
                     /old_locus_tag="GCM10018780_11840"
     CDS             complement(25290..25916)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.5"
                     /locus_tag="IE325_RS05855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11840"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_190068632.1"
                     /transl_table=11
                     /translation="MSSRGLSRGAIVAAAVRIADAEGIAALSMRRLATELDSGVMSLYR
                     HVANKDTLLTAITRAACDEHPYPEPAPPDWREAMRLAARLDWEVYCTHPWALVTSSSAR
                     HFSDTSCLDWMVDALADLTDDPDLARSFSIAVWSYVQGVCIQHLAQQLLSGGDKPEQSP
                     LRATEDDFDLGLETLLDGMEQRAARHRSDDADTPFTRTFPVTAPR"
     misc_feature    25982..25996
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.16"
                     /tool="antismash"
     misc_feature    26012..26030
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.44"
                     /tool="antismash"
     misc_feature    complement(26016..26034)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.8"
                     /tool="antismash"
     misc_feature    26035..26053
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.86"
                     /tool="antismash"
     misc_feature    complement(26039..26057)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 22.66"
                     /tool="antismash"
     gene            26097..27611
                     /locus_tag="IE325_RS05860"
                     /old_locus_tag="GCM10018780_11850"
     CDS             26097..27611
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018891165.1"
                     /locus_tag="IE325_RS05860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11850"
                     /product="MFS transporter"
                     /protein_id="WP_190068633.1"
                     /transl_table=11
                     /translation="MTSLDLVAERADRRAWLGLVIVLGPVALVAMDGSVLYLAMPSITS
                     AITPSTDQALWILDIYGFVVSSLLIAFGNLGDRYGRLKFLVTGAVVFGAGSAGAAFAPN
                     PEILIACRALMGLGGATLLPAGLAIIGNLFHNPKQRSQAIGIFAATFAAGFAAGPVIGG
                     LLLSRFDWGAVFLINIPVVVLFVVFAPVLLREVRTSNPGRVDALSVVLSAVGILLAVYS
                     IKTAAAEGFSLSQIAIGVVGVAVLVWFARRQLTLEYPLLDLRLFKDHVFAVAILTGLLS
                     LVAWAAAGYLSGMYLQSVLGYSVLTAALLALPGAAVLTAACIGASGVVDRIGKRSALIA
                     SHFFMGFGLLLLLLTTTEHGVAAFIASSVVTGVGYGFSFSLVADTAVAAVPAERAGSAA
                     SIAETSNELGNALGISLLGSLAALLFRLTGPDAAGTLDETLDTRGLSPATAEEAKEAFL
                     TGLHVAVGVASALCLALGILALRWVPKEETPPSEPTPDPESMTATH"
     misc_feature    26112..26114
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(27955..28842)
                     /locus_tag="IE325_RS05865"
                     /old_locus_tag="GCM10018780_11860"
     CDS             complement(27955..28842)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF041195.1"
                     /locus_tag="IE325_RS05865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11860"
                     /product="ScbA/BarX family gamma-butyrolactone biosynthesis
                     protein"
                     /protein_id="WP_229911678.1"
                     /sec_met_domain="AfsA (E-value: 1.2e-12, bitscore: 43.3,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHTTLAPRPGTASSAQLSSYAHLRREEYLLVTGSRRLAAGEFAL
                     GVRWPAVQGDLPYDPRILAQTIRQTGLVVAHAEYGVPLTHQTMLSTLSFRIAPGLRIPR
                     GRTSALDVHVTVSEAGGRRRTTSALHMTFQVLRDGEPLARAESEFTWISERVYDRLRGT
                     RRSVHWGSWPVPAPLDARLAGRAGPSDVALSAGDRPGRLLLRNDPGNHLLFDHPVDHVP
                     GLALLEAADQAAHTLHSPTPFTSTTIEATYWRYVEFDQPCWLETEPLPTPGAVRVTGTQ
                     QGEPAFRVDFGTTD"
     misc_feature    complement(28929..28944)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.8"
                     /tool="antismash"
     gene            28975..29598
                     /locus_tag="IE325_RS05870"
                     /old_locus_tag="GCM10018780_11870"
     CDS             28975..29598
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003970700.1"
                     /locus_tag="IE325_RS05870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11870"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_190068634.1"
                     /transl_table=11
                     /translation="MGRQQRAVRTRRVILEAAAAMFNDFGYDATTIGGLIERTRLTRGG
                     LYFHFASKEQLARAILDETSALRPVPPQPLKLQEWVDMALLLGYRLPRDPLLGATVRLS
                     VDLRARALFGTRWPQWTDAGEELLCAARDRGELLGHVEPAEVARLLTASWAGIRLLDEA
                     LPDGELCTQFAVFLELVLPNIACPGVLAKLDTSPHRAAALDRAT"
     misc_feature    29624..29642
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.87"
                     /tool="antismash"
     gene            29684..30838
                     /locus_tag="IE325_RS05875"
                     /old_locus_tag="GCM10018780_11880"
     CDS             29684..30838
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003988487.1"
                     /locus_tag="IE325_RS05875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11880"
                     /product="transposase"
                     /protein_id="WP_190068635.1"
                     /transl_table=11
                     /translation="MRDGLDDGAAAGEGPIPDVLDAELCRRLFGSLHRSGQRVKAEQYV
                     RGLLSVRGRKTLRSIAAQFDGASAQQNVHHFIASSPWEWVPVRHALARQAQRALAPQAW
                     VIDSLLIPKAGPHSVGADPQPTPLGTVNGQQAVGTWLTSERAAVPVDWQLRLSARWTVE
                     PLRHRASVPPDAVPGTVEECVRQAVVGLMGVGEMPRLPVVVDVAEADGISIARFLASTG
                     LPFAVRVDAAAPVRIDRSLLPKYGDLLHTAGELSESLPHLRQQVNPGDGRTTAAAIPVS
                     ASPSGREAMTLLGECPPGRPAEPRLWLTNFTADRLAPALRLTRLPGVVERDCAEISDGV
                     GLRDFAGRSFPGWHRHITLACVAHLVSAAARRGDVTHINRTTVR"
     misc_feature    30965..30980
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.5"
                     /tool="antismash"
     gene            30975..32168
                     /locus_tag="IE325_RS05880"
                     /old_locus_tag="GCM10018780_11890"
     CDS             30975..32168
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004948185.1"
                     /locus_tag="IE325_RS05880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11890"
                     /product="transposase"
                     /protein_id="WP_229911679.1"
                     /transl_table=11
                     /translation="MLSLDLRPPTAARGTLTTPFPSRSHDDRLTEISSMLFASLSRSDQ
                     CRKGMQYLRGLLETPGRKSIRNIAALLGEQASEQNLHHFISGSTWDWTPLRRALAEHWI
                     GERPPRAWVVQPVIIPKTGRHSVGVDKHFFPTLGQVLNAQRAIGVWAASDTISAPVNWR
                     LHLPQTWLKDALRRSQVSIPDGVPVETLSESVVEACLEAVNRWRLPVRPFVLDSCEVHA
                     VPIFTRLHTAGMPLLVSVCEDQPLTVADPALPGGGPGQLTAEQIMLMARDLRRPVMAAD
                     HRRGATPFTHWAATVRVTGPSLPAPSAGQGEVRLLGVGEEDGRWPAKLWLTNLTEVPPA
                     SLVRLSKLADRVDLDFTEITDRVGIRDFSGRSFDGWHRHVTLASAAHAVVALAKGAQ"
     misc_feature    31131..31133
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            32577..33779
                     /locus_tag="IE325_RS05885"
                     /old_locus_tag="GCM10018780_11900"
     CDS             32577..33779
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018891162.1"
                     /locus_tag="IE325_RS05885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11900"
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="WP_190068636.1"
                     /transl_table=11
                     /translation="MDDALLDIRYEQALQQPPWEDEAQVLRVRKELAARLPLVGAEDVR
                     TLRSMLAQVAAGDAHVVQTGDCAEDPAESTAGHVARKAGLLNMLAGQLEMDTSRPVVRV
                     GRMAGQFGKPRSRPTERVDGLELPVYRGHMVNSPEPDPELRRPDPGRLLSGYLAARDVM
                     GHLGWLDAPGPARIGAPVWTSHEALLLDYEVPMLRRQPDGELLLTSTHWPWIGERTRQL
                     DGAHVALLADVVNPVACKVGPTMTPGELLALCERLDPRRQEGRLTLIARMGAGTAAERL
                     PSLVAAVRAAGHPVIWLTDPMHGNTVSTPDGLKSRFLQTVTREIDEFQHAVAAAGGVAG
                     GLHLETTPDDVTECVRELSEVDRVGTRYTSFCDPRLNPVQALSVVSSWWMTGRSLQPTA
                     A"
     gene            33868..34527
                     /locus_tag="IE325_RS05890"
                     /old_locus_tag="GCM10018780_11910"
     CDS             33868..34527
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018891161.1"
                     /locus_tag="IE325_RS05890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11910"
                     /product="isochorismatase family protein"
                     /protein_id="WP_190068637.1"
                     /transl_table=11
                     /translation="MAGIPPIEPYPLPSADDLPGNTAGWSADPDRAVLLVHDMQRYFLR
                     PFPASLREPLVRNAALLRERAVATGMPVAYTAQPGGMTDEQRGLLKDFWGPGMRVDPVD
                     REVVEPLTPGPDDRVFTKWRYSAFFRSGLLEWMREQGRDQLVLCGVYAHVGVLMTAVEA
                     FTQDIRTFLVADAIADFSAEYHRLAVEYAAQRCAVVSTTGTVLGQLGTATTAGATV"
     gene            34524..36437
                     /locus_tag="IE325_RS05895"
                     /old_locus_tag="GCM10018780_11920"
     CDS             34524..36437
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018: isochorismate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018891160.1"
                     /locus_tag="IE325_RS05895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11920"
                     /product="anthranilate synthase family protein"
                     /protein_id="WP_190068638.1"
                     /transl_table=11
                     /translation="MNAPADLLARVLAPHPPAFALLHRPQTGGADTVDVLSGGISTPAT
                     LADLPLPDGAAPADGPRHELLTLIPYRQIAERGFAGPDDGEPLIAMTVADQARLPLDEV
                     LRRLPDVPIDMTGGDFDVDDDTYAETVRRVITDEIGTGEGANFVIKRSFVAEISDYGTH
                     SALSFFRRLLRGESGAYWTFVVHTGERTFVGATPERHLSLLDGTAVMNPISGTYRYPPG
                     GPTLPGVLDFLADRKEADELYMVVDEELKMMARICDTGGRVVGPYLKEMARLAHTEYFI
                     EGRSTRDPRDILRESLFAPTVTGSPLESACRVISRYEPEGRGYYSGVAALIGRDAGGGR
                     ALDSSILIRTADIGPSGRVRIGVGATLVRHSDPDSEVAETRAKAAGLVAALQADRPAAG
                     QASAGAVLLGDHPDVRASLERRNTTLAGFWLAGDGGRERPLPDLAGSRVLVVDAEDTFT
                     SMIDHQLRSMGLDVTVRRFDDLYGFDGHDLVVMGPGPGDPRETGHPKIAHLRSAIDTLL
                     TERRPFLAVCLSHQVLSMRLGLPLTRREVPNQGVQQEIAFFGARERVGFYNTFAARSAE
                     DKVEVEGVGLVEVSRDAETGEVHALRGPHFASMQFHAESVLTEDGVRLFGALMTDVLGV
                     RL"
     gene            <36407..36772
                     /locus_tag="IE325_RS05900"
                     /old_locus_tag="GCM10018780_11930"
                     /pseudo=""
     CDS             <36407..36772
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010470454.1"
                     /locus_tag="IE325_RS05900"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11930"
                     /product="shikimate kinase"
                     /pseudo=""
                     /transl_table=11
                     /translation="DDGRPGRPALTTPRRRALAGHDGVLAPGGGAVLDAGTRALLAGRP
                     VVWRSMGADAAARRAGLDLARPLLAAEPHPRWWELAEARRHLYAEAASARVATDGRTPD
                     EVAEAVLDVLELTTRPR"
     misc_feature    36852..36866
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.16"
                     /tool="antismash"
     gene            36881..37591
                     /locus_tag="IE325_RS05905"
                     /old_locus_tag="GCM10018780_11940"
     CDS             36881..37591
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019349.5"
                     /locus_tag="IE325_RS05905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11940"
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="WP_229911680.1"
                     /transl_table=11
                     /translation="MALRPIARPSTAREVIALLHRELADGAWPIGSRIPSETELAAQLG
                     VSRPTIREAVSALVHTGMLEAQRGKGVFVRSVSDPAPMLQSIELADVRDVFEVQLCFDV
                     QAAHSAALRRTPEDMARLRELLRARAEAAGRDDAEFGKRDAALHLAVVEAARNVTLTEC
                     YRFFVGRLQESLDLFAGADTHLECGVEAHEALVRAIEEQDPEAAAAAARHVVRTSLDAL
                     EGLLAVRAAEPKGG"
     gene            37650..40496
                     /locus_tag="IE325_RS05910"
                     /old_locus_tag="GCM10018780_11950"
     CDS             37650..40496
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.5"
                     /locus_tag="IE325_RS05910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11950"
                     /product="BREX system ATP-binding domain-containing
                     protein"
                     /protein_id="WP_190068639.1"
                     /transl_table=11
                     /translation="MPTPGDRRLVGREREQAALRAALDATAAGRGSLLLFHGPSGSGKS
                     LLLRTAGARAALRGMAVSTARLARLDQHSAMAPLLAALSTGPHPVLSAVQAGSLAEFAD
                     RPTHWSRLIERLHRLIERRAAHSPLVIVLDDLQWADELTLAALETLLPRLADVPVLWLA
                     AYTDFPVVRPTRDALDRLPAAHAEVVPLSALDGPAAAELAAQLLGTVGPEDIRRVVTAT
                     GGIPALIERLVQLLREEGRIRTEDGTVRVLGGHPPADLARAAAPVLSGLAQQTRELLQV
                     GAVLGPRFSLREVSALTGRSTMELATAAQEAAAAGLLEDDGAAFRFRAPLVHQALHDSL
                     LGPVRRALHAEAARLCAAEGRPCPETIGHLILSGTEEDLEQGAAHLEWLKRNEDSVPSH
                     EREELSRALLTQLRRYDPLATGPVRTAVRLFLATGQPGTAHRMLDAALAGAGWETDAEA
                     EAFAELVEVLLRSGQAHDALRHLRRAAEDTRSPARRQAWLTALEARCLAAAGNDPAHAA
                     RLARSAVVLARQTADHASAALGTALLAGFAQRAGDIGTASRLAGEAVAGGPYGAERSFG
                     WGLAVPALVLSSAGRPLDAGEVLKAWRNATGEQAWGWAAPRWHLARSVQLWHCGRLADA
                     EQEAQAGLEACGRLDDPGSRKALRAMLTLLATVRGDLERAAARSASPEGPPSGSVGAFP
                     ALVGALLLDASGDPEAAVRQLAGLWADPERHTWLLAADPLVLPHLVRIALRAGAHEQAA
                     EAVDLARRLARQSPGITPVTGAALHSQGLYRGLAAPLHRAVRVFRGGSHPLALASALED
                     AADATRAQGEPLRATEMLQEAQRIYVAAGAGLGAERVRRRTRFSPGRTVGELPAARRAP
                     AVPSARAAEGTADWDSLTPSEVRVVRLVAEGLTNRETAQRLAVSAHTVDSHLRRAFAKL
                     GVSRRVELARHVLAHTSK"
     misc_feature    37704..37706
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    38883..38885
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            40528..42108
                     /locus_tag="IE325_RS05915"
                     /old_locus_tag="GCM10018780_11960"
     CDS             40528..42108
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1066: alpha/beta hydrolase domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012363.5"
                     /locus_tag="IE325_RS05915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11960"
                     /product="carboxylesterase/lipase family protein"
                     /protein_id="WP_190068640.1"
                     /transl_table=11
                     /translation="MRAADAASATTRTETEVSGGPLVGRLEGPGGLVAAYRGVPYAAPP
                     VGPDRFAPPRPHPGWSEPLRADGAVGTVPLQLPSPFAALLGDPLDPPHTEACLTVNVWA
                     PVGPGDGPRPVLVWLPGGSFLTGGADLPRYDGAELAAREGIVVVLVNYRLGALGFLAPS
                     WAEPAAVEGVGTSLSFRMPQGATHVTNAGLLDQIAALRWVGREIHAFGGDPDRVTVVGQ
                     SAGGQSLAALLALEQVRPLFRRAVLHSAPLGMAPQTRQEAALVADDFLAALGADAGRLR
                     TVPGERVLLAQRQVLARPRRRGDVRPPFQLVADDAVVAADLPGALRTAPPPDGLDLLAG
                     VTRHECALWFGEDPGLDGLTREEVAAEFSAVFGPRAQEALSHYTPGTEWRVAFEELKTD
                     AFFTAPTQEFADLADSWGATVRLFRFDWRVPGRHARLRACHCAEIPFLLGRTEARHAPL
                     FADADQEEMAALRGRMRRLWGEFVRTGTMTDHWPPHRREQPAVRVVGGERDGEVLGALL
                     ESGRRRLWE"
     gene            42159..42299
                     /locus_tag="IE325_RS05920"
     CDS             42159..42299
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE325_RS05920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_190068641.1"
                     /transl_table=11
                     /translation="MVRTGTTADNWPPHHREQPAVRVVGGERDGEVLGALLEPGRGRMW
                     E"
     gene            complement(42480..43397)
                     /locus_tag="IE325_RS05925"
                     /old_locus_tag="GCM10018780_11970"
     CDS             complement(42480..43397)
                     /EC_number="1.14.11.-"
                     /GO_function="GO:0051213 - dioxygenase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: TauD (34-292). E-value: 1.4e-33. Score:
                     108.7. Matches aSDomain:
                     nrpspksdomains_IE325_RS05925_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1046: Dioxygenase TauD/TfdA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606945.1"
                     /locus_tag="IE325_RS05925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_11970"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_190068642.1"
                     /sec_met_domain="TauD (E-value: 1.7e-32, bitscore: 108.7,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDHARVTSYGSGTGLLLTPAEPGTTLGTLAPGQVIRTLREAGFL
                     LLRGFRPDLEQFSAFVGAHSERVTLDPARSFHGGSTAQKVDAGHEAVGLHLENGNSPFA
                     PTLTWFYCEKAASSGSQTTVCDGHRVWDALSEEARGLFRAHEIVYSRRVEETKWKAFAA
                     FHLGTSDAASVTVDQLRELAGGPGETVIDLLGDGSIHYAYRVSAAHGTLFDERLAFANS
                     ILGPSNHYEKPRITFADGRDIPVRILKEVESVTEDLTEELAWADGDVALIDNTRVMHGR
                     RAITDPERSIFNAQSDLDRTLLTI"
     aSDomain        complement(42522..43295)
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS05925_TauD.1"
                     /evalue="1.40E-33"
                     /label="IE325_RS05925_TauD.1"
                     /locus_tag="IE325_RS05925"
                     /protein_end="292"
                     /protein_start="34"
                     /score="108.7"
                     /tool="antismash"
                     /translation="VIRTLREAGFLLLRGFRPDLEQFSAFVGAHSERVTLDPARSFHGG
                     STAQKVDAGHEAVGLHLENGNSPFAPTLTWFYCEKAASSGSQTTVCDGHRVWDALSEEA
                     RGLFRAHEIVYSRRVEETKWKAFAAFHLGTSDAASVTVDQLRELAGGPGETVIDLLGDG
                     SIHYAYRVSAAHGTLFDERLAFANSILGPSNHYEKPRITFADGRDIPVRILKEVESVTE
                     DLTEELAWADGDVALIDNTRVMHGRRAITDPERSIF"
ORIGIN
        1 ggtggacggc tggtcctgac gggcatcccg gcgccgggcg cggacgggct ggacccgacc
       61 gatctcgtcg tacggcagct ggaggtgcac accgtgttcg gcgcggcgcc ggacgcctgg
      121 gcgcacaccg tgcgggtctt cggcgccgga ctcctcgacc cgctgccgct ggtcacgcac
      181 gagctgccgc tggaggagtt cccgcaggcc atcgagctgg tcgggtccgg cgatccgaag
      241 gtcggaaagg tcctgctgcg gccatgacac acccctgagc cgtacgccgg tacggggtac
      301 ctgacgactt cgtaccggcg tacacccaaa gccccgcacg accagagtcg cgaccctcgt
      361 ccgaaatatc gaacacgaag gaccacttgt gaccgacacc accgctccga caccgcgccg
      421 acccggcgag caggcgctcg ccgcactcgg cctgggggcg cccgccctcg acccctccga
      481 cgcctctccg cacaccttcc ccggcggggg ccgttggcgc accgaggttc cctccgtgga
      541 gggccccgag gcgctcgccg tggtcctcaa ggagtcctcg cggctcgatg tgccgatcca
      601 ccggatcagc cagggcagcg gcatctggat gctcagcgac gccgagatca ccgagatggt
      661 ggaggcgacc gccgagcgcg acatcgagct ctgcctgttc accggcccgc gcggcacctg
      721 ggacatcggc ggctccaccc gtaccgactc caagggcggc gggctgcgcg cccggggcca
      781 cgacgcggtc gccgggtgcg tcgaggacgc cgtacgcgcc accgagctgg gcgtgaagtg
      841 cctcctcgtc gccgacgagg gtgtgctgtg gacgcttcac cgggcgcggg tcgcggggat
      901 cctgccggcc gacacgacgc tcaaggtgtc ggcgctgatc ggtccggtca acccgacggc
      961 gtacgccgtg tacgagaacc tcggcggcga ctcgatcaac gtgcccagcg acctgacgct
     1021 ggatcacctc accgagatcc gccgggtctc ggccgccccc atggacatgt acatcgaggc
     1081 ccccgacgat ctgggcggtt acatccggat gtacgaggtc gccgagctga tccggcgcgg
     1141 cgccccgctg tacctgaagt tcgggctctc caaggccccc ggcatctatc cctacggcca
     1201 ccacatgcgg gacctgacgc tggccaccgc caaggaacgc gtacggcgcg gccggctggc
     1261 gctggacctg ctcgcacggc acggagctga cggcgacatg gcgcctctcg gttcacggct
     1321 gcccgggacg ctgacgcgat tcgaaactcc cgcataacgt tccggacaaa cccccttcac
     1381 agaagaagac gcagtcgaac acaatcccac acaccatcgg tggagcgttc agctctcgaa
     1441 agcgtctccc cttcgccaga ccgagccctg ctcacaacat caaggatgat gaccatgcgt
     1501 actcgcagag ccgcactcgc cgccatagcc tccgccgcct ccctcgccct gaccctgtcc
     1561 gcctgcggcc agagcggcga gggcgggtcc aaggacgagg gcggcgacac caagggagcc
     1621 accatcggca tcgcgatgcc gaccaagtcc tccgagcgct ggatcgccga cggcaacaac
     1681 gtcaagaagg acctggagtc caagggctac aagaccaggc tggtctacgg cgaggacgac
     1741 ccggaccagc aggtctcgca gatcgagaac ctgatcacgc agggcgtcaa ggcgctgatc
     1801 gtcgcggcca tcgacaacaa gtcgatgaac aacgtgctcc agcaggccaa ggacgccgac
     1861 atcccggtga tctcctacga ccgcctgatc ctcggcaccg agaacgtcga ctactacgcg
     1921 tcgttcgaca acgagaaggt cggcgagctc caggccaact acatcgtcga gaagctcggt
     1981 ctgaaggacg gctccaagaa gggcccgttc aacatcgagc tgttcgccgg ctccaacgac
     2041 gacaacaaca cccgctactt cttcggcggg gcgatgaagg tcctgcagcc ctacatcgac
     2101 aagaagcagc tcgtcgtccg ctccggccag accaagctga cccaggtcac caccctgcgc
     2161 tgggacggcg gcaccgccca gaagcgcatg gacgacatcc tgacctcggc ctacaagagc
     2221 gagcgcgtcg acgcggtcct ctcgccgtac gacggcatct ccatcggcat cctctcggcg
     2281 ctgaagtcgg acgactacgg ctccaaggcc aagccgctgc cggtcgtcac cggtcaggac
     2341 gccgaggtcg cctcggtgaa gtcgatcatc gccgcccagc agtcgatgac cgtctacaag
     2401 gacacccgtg agctcgccaa ggtcgcctcg ggcatggtcg acgccctgct caacgacaag
     2461 aagccggagg tcaacgacac caagacgtac gacaacggcg cgaaggtcgt ccccgccttc
     2521 ctgctggagc cggtcgcggt cgacaagacc aactaccaga aggaagtcgt ggactccggc
     2581 tacatcaagg cgagcgacct caagtaagcg ccggatccta ctgattggaa ggcacgacca
     2641 tggcgggacc cgtcctggaa atgcgctcga tcgtcaagac ctttcccggc gtcaaggcgc
     2701 tgtcggacgt cacactgacc gtccagcagg gcgaggtcca cgccatctgc ggggagaacg
     2761 gggccggtaa gtcgaccctg atgaaggtcc tctccggcgt ccacccgcac ggcacctacg
     2821 agggggacat cctcttcgag ggcgaagtct gcgagttcaa ggacatccgg gcgagcgagc
     2881 agcgcggcat cgtcatcatc caccaggagc tggcgctgtc gccgttcctc tccctcgcgg
     2941 agaacatctt cctcggcaac gagcacgcca agggcgggtt catcgactgg cgggagacgc
     3001 tgcggcacgc caccgaactg ctgcgccggg tcggtctgac cgaccacccg gacacccgcg
     3061 tcgccgacat cggcgtgggc aagcagcagc tggtggagat cgcgaaggcg ctgtcgaaga
     3121 aggtgaagct gctcatcctg gatgagccga ccgcagccct gaacgacgag gacagcggca
     3181 aactcctgga tctgatccgg gagttgaaga agcagggcat cacctcgatc atcatctccc
     3241 acaagctcaa cgagatccgc aaggtcgccg actcggtgac catcctccgc gacggcaaga
     3301 ccatcgagac cctcgatgtg aaggccccgg agaccaccga ggaccggatc atcagcggca
     3361 tggtcggccg ggacctggag caccgcttcc ccgaccgcac cccgcacgag ccggaggagg
     3421 gcgccgcccc ggcgctcgag atccgcaact ggaccgtgca ccacccgatc gaccagcagc
     3481 gcaaggtcgt cgacgacgtg tcgatccagg tgcggcgcgg cgagatcgtc ggcatcgccg
     3541 ggctgatggg cgccggccgc accgagctcg cgatgagcat cttcgggcgg acgtacggcc
     3601 gttaccacgg cggcaccgtc ctcaaggacg gcacggagat ccgcaccaag accgtccccg
     3661 aggcggtcag gaacggcatc gcgtacgtca ccgaggaccg caagcactac ggcctgaacc
     3721 tcatcgacac catcaaccgc aacatctcgc tcagcgcgct gggcaaggtc gccaagcggg
     3781 gcgtggtgga cgagcacgag gagcggcagg tcgccgaggg cttccgcaaa tccatgaaca
     3841 tcaaggcgcc gaccgtcttc gagccggtgg gcaagctgtc cggcggcaac cagcagaagg
     3901 tcgtcctcag taagtggatc ttcgcgggtc cggatgtact gatcctggac gagcccacgc
     3961 gtggcatcga cgtcggtgcc aagtacgaga tctacacggt catcgaccag ctggccgccc
     4021 agggcaaggc ggtcgtcttc atctcctccg agctgccgga gctgctcggg atgtgtgacc
     4081 gcatctacac gatggccgcg gggcggctga ccggtgagtt ctcgcgggcc gaggcctcgc
     4141 aggaatcgct gatgcgccag atgacgaagg acaaagaggt aacccgatga gcacggatgt
     4201 gaccgccaag accccggccc ccgcgccgcc ggggaagagc ggaggggccg cgggcgacgg
     4261 cctgctccag ctggtgctgg acggcatgcg ccgcaacatg cggcagtacg gcatgctgat
     4321 cgccctcggc ctgatcgtgg cgctgttcgc cgtgtggacc gacggtgacc tgctgctgcc
     4381 gcgcaacgtc tccaacctgg tgctgcagaa cagctacatc ctgatcctcg cgatcggcat
     4441 gatgctggtg atcatcgcgg gccatatcga cctgtcggtc ggctcgctga cagcgttcat
     4501 cggctcgatg gccgccgtct tcatggtcaa gaacgatctg ccatggccgg tcgccgtcat
     4561 cctctgcctc gccatgggcg ccgtcgcggg cgcggcacaa gggttcttca tcgcctacgg
     4621 cggcatacca tccttcatcg tgaccctcgc gggcatgctg atcttccgcg gtctgaccga
     4681 gatcttcctt gagggccaga cgctcggccc gttcccggag ggtctgcaga aggtcgccaa
     4741 cggcttcatg ccggaggtcg gcccgaacac caactaccac aacctgacac ttctgctcgg
     4801 cttcggaatg atcgcgttcg tggtcttcca ggagttccgc gaccgccgcc gtcagcagga
     4861 gttccacctc gatgtcccgc ccttcaacct gttcctgctg aagctggtcg cgctcggcgc
     4921 cgccatcctc acgctgacga tgctgctggc cagctacaag ggcgccccga tcgtgctgct
     4981 catcctgggc gtgctgctcg tcggcttcgg ctatgtgatg cgcaacgcga tcatcggccg
     5041 tcacatctac gcgatcggcg gcaacctccc ggccgccaag ctgtcgggtg tgaaggacaa
     5101 gaaggtcacg ttcctgatct tcatgaacat gggcatgctc gcggccctgg cgggtctggt
     5161 cttcgccgcc cgcttcaacg cggcctctcc caaggccggc ctcaacttcg agctggaggc
     5221 catcgccgcc tcgttcatcg gcggcgcgtc gatgagcggc ggcgtcggca cggtcctcgg
     5281 cgcgatcatc ggtggcctgg tcctgggcgt gctgaacaac ggtatgaacc tcgtcggcat
     5341 cggcaccgac tggcagcagg tcatcaaggg cctggtgctg ctggcggcgg tcgggttcga
     5401 cgtgtggaac aagcgcaagg tcggttcgta agaccgagca gggccctgcc agaacggcgg
     5461 ggcccggttc tttcccagca gttcccagca gttctcggac tactcagagt ttcagcagct
     5521 tcccaaagga gtggagccgc acatggatat gaggagacga acggtcatag caggggctgc
     5581 ggcggcgggg atcaccgccg cgaccgtcgg cagcgcaagc gcacacgcca cgggaggcag
     5641 gacgccggtg aagtcgctct tcggcaagct cgccgacggc acggaggtct acagctggtc
     5701 gctggccaac ggcggcacgc ggatgaaggt cctctcctac ggcggcgtgc agtccctgga
     5761 ggtcccggac cgccgcggcc ggtacgccaa catctcgctg ggcttcgaca acatcgagga
     5821 ctacgtcgcc aagagcccgt acttcggcgc gctgatcggc cgctacggca accgcatcgg
     5881 caagggcaag ttcacgctcg acggcaaggc ctaccaggtc aacgtcaacg acggcgagaa
     5941 cagcctgcac ggcggcgcca agggcttcga caagcgggtc tgggacgtcg agccgttcac
     6001 caagggcacg gacgtcggcc tgcgcctgta ctacacctcc gtcgacggcg agatgggcta
     6061 cccgggcacg ctcaaggtca aggtgacgta caccctcacc aggcacggcg actggcgcat
     6121 cgactacgag gccaccaccg acaaggccac cgtcgtcaac ctcaccagcc acgtgtactg
     6181 gaacctcgcc ggcgagggaa gcggcacgat cgagaaccac cagctgaaga tcgacgcctc
     6241 ccgctacacc cccgtcgact cgggcctcat ccccaccggt gagctggccc gcgtcgcggg
     6301 cacccccttc gacttccgcc gtacgaaggc gatcggcgag gacctgcgcg agccgcacca
     6361 gcagctcctc tacggcaagg gcatcgacca caactgggtc ctcgacaagg gcatctcgcc
     6421 ccgccccgag tggatcgcga ccctgaagga cccgtcgtcc ggccgcaccc tgcgcatggc
     6481 gaccaccgag cccggcctgc agttctactc cggcaacttc ctcgacggca ccctcgtcgg
     6541 ttcgggcggc aacgtctacc ggcagggcga cgccctgtgc ctggagacgc agcacttccc
     6601 ggactccccg aacaagccgt cgttcccgtc gacggtactg cgcccggggc agacgtaccg
     6661 ttcgacgacg gtgcactcgt tcacctgctg agcgagttcg tccgttcttc acaggtggca
     6721 cacaagttct caccgatttc tcagcgggtg aacagcgcca ccccagcctc cgtatgtatg
     6781 ggcggcccgt gctcccccgc gcgggccacc caaagacgac gggcccggtc gtccccgccg
     6841 ggcccgcccc atacggaggt tccatggccg acaacgtcac ctcgctgttc cgcagtacgg
     6901 cggcacacag cccgtcgatg gcggcgctga cgcgtgaggg cggcgacgga gccggtccgg
     6961 tcgacttctg tatcccctgc aacccgtact tccccacccc cgagatgttc caggacatgg
     7021 gggcacggtt gcgggacatc atcacctact acccgagcag cgccgacacg atcacggccg
     7081 aactgtgcag cctgctccag cttccgccgc agtgcgtggc gatgggcaac ggatccaccg
     7141 aactgatcac ctggatcgat cacttgatgg tccgtgagtc cctcgccatc cccgtcccca
     7201 cgttcggccg ctggaccgac cagccgatgg agaccggcaa gcgggtcgac atgttcccgc
     7261 tccaggagtc cagcggcttc gccctggacc tggcccagta cgccgagttc atacgggccc
     7321 gggggacacg ggtcgcggtc atctgcaacc ccaacaaccc cgacggcggc ttcctccaca
     7381 agcacgcgct ggtccagttc atggacgcca tggccgacct ggacctggtg atcatcgacg
     7441 agtcgttcct cgaattcgcc gacgccgaac aggaaccctc ggtggtccag gaggcgatgc
     7501 tccgcccgaa cgtcatcgtc ctgcgctccc tcggcaagaa cttcggcctg cacggcatcc
     7561 gcttcggcta cctcgtcgcc aacccggccc tggccggcat ggtccgctcg atgctgccga
     7621 agtggaacct caacgccttc gccgagcatg tggtgttcat gctcaagaac cacggcgcgg
     7681 agtacgcgca gagcctgcac caggtgcgcc gggaccgcct cgacatggcc agccacctcg
     7741 cccagctgcc cggcctgacg gtctacccgt cgcagggcaa cttcctcttc gtgcgcctcc
     7801 ccgtgggcgc cgagggcacc gtggtccgcg accggctgct caccgagcac cggatcctgg
     7861 tccgcgagtg cggcaacaag atcggttcgt ccagccgctt cctgcgactc gtggtgcgcc
     7921 cccaggtgga cgtgcgtcgc ctggtgtccg gcctggaaca ggtgctctac gggaccagga
     7981 ggggagccgc cgtacccgag ctgggtacag ggaccaacta cagctcgggt acggcggccg
     8041 tggaccgtct ggtcagctcc acgaacggcg cgggtgtggc ggggctcgcc gcgcaggcca
     8101 tggcggcgcc tcagccgcag gcggtgccac aggcggtgcc acaagcggtg ccgcaggggg
     8161 gtggcatgcc gatgccggcg ccgatgccgg tggcaccgat gccgactcct gtcccggccc
     8221 cggcccccat gccggctccc gctcccgtcg cgcccgcgcc gatgccgttc ccgtcgcccg
     8281 tggcgccggc cgcggcggtg gtgccgccgc cggctgccgg gcccacgccg ccgggggtgc
     8341 cggcccgtgg ggggcttacg gcggcgcagg tacgggggac gacggggccg gggttgactc
     8401 cggcgccggc gaccgggtgg ccgaacgcgc agagttggcc gaatgcggcg gggatgcagg
     8461 cggggtagcc cttcaggtcg gcttggtcac gccgggttga ggcgccactg ttggcagttg
     8521 ttgcccagcc agctccactg ccgtacgtcc gccccgtccg cggtcccgca gttcgccaca
     8581 tccgccacct tgcccgtggc ctgattgacg atccggacga agccgccgtc cgtcgccacg
     8641 aaccggaagc gctggcaggt gttgtcgagc caggaccact ggcgcaggtc ggcgccgtcg
     8701 gcgctggagc agttctcggt gtcgaggacc ttgccggtgg cgacgttgac gagccggtgg
     8761 gtgtcgtcgc cgaggtcttc caggcgccac ttctggttgt tgccgccgct gcacgaccac
     8821 tgctgcacat tggcgccgtc ggcggtcgaa ctcccggcca catcaaggca cttgccgctg
     8881 ttgcggttgg tgatcgtgta gttgctggag gaggaggagg gctcgccgga ggggccggtg
     8941 agggcagcgc cgagccggac cggggtgccg aagttcggcg tgccgtcgga gttccaggtg
     9001 aacttctgcg cccgggccgt acggccgttg tcgcagccgt cgctcgcgct gtcgttggcg
     9061 tggtagacga tccagttctc ggtgccgtcg ggcgaggtga agaagccgtt gtggccgggc
     9121 ccgtagaccc cgttggcatc actgcgctgg aagacggggg tggacttctt ggtccaggag
     9181 gcggcggaca acggatccga tcccgtcaga gtcagctggc cgagcttgta gtcgggtgtc
     9241 cagcagccgc tgccggagta gatgaggaag gtcctgccgc cgcgctggag gatctccggg
     9301 ccctcgttga cggtgccgtt gcgctcccag tcgtaggtcg gggtggagat ggtggagaag
     9361 ccggtggcga gggtgtaggg attcgacatc ctggccgcga cgaggttctg cgtaccgcca
     9421 ctggcgctgc cgaagagata cagctgcccg ttgatggtgg cgacgttcgg gtccagcatc
     9481 caggcggagt tgagctggtt cttgtaggtg tacgggccca tgggatcgga cccggcactc
     9541 tccagcacat gcgtgcgctg ggtcgggttg tagtcggaga cgttctgccc ggcgacgtag
     9601 tacagatacc agcggccgtt gaggaaatgc agctccggcg cccagatgtt gcagcaccgg
     9661 ttggcggcgt cgcccttcca gacctgcacg ctgggtgcgg aggcgagccc ggcgagggtc
     9721 ggggccttcc gcatggtgat gacatcggtc caactggtcg tcaccaggta gtagttgccg
     9781 tcgtggtacg agatccaggg atcggcgcct ttctgcacct tgaccggatt ggtgaaggac
     9841 gccgcactcg cggacggctg tccgatcgac agggccagca gcagcgccgc cagcagggtc
     9901 agtaggcgac gggccatccg ctgctccagt tcagaaggtt gatgcccagc ttgggcgtgc
     9961 cgttgtcgtt gccgtcgtag tagtggtaga cgatcaggtc cccgtcggcg tcgttcatga
    10021 tcgactgccc gccgggcccg atgacgctgc cgtgcgactc cagaaccggc gtcccgccgt
    10081 tgctcatcat ggagacgccg ttcttgtcgc ggtacggtcc ggtgatgctc gtggcccgcc
    10141 cgaccttcac cttgtaggtg ctgctggtgc cggcgcagca ggtgtcgtag gaggcgaaga
    10201 ggtagtagta gccgccccgt ttgacgatgt agggcgcctc gacggccttg gttccggtgg
    10261 ggcgggaggc gagcgagtac cgggtggtgt tggaggacag ctgcttcccg gtggacggat
    10321 tgatctggat catcttgatc ccggtccacc aactgccgaa ggacagccac cacttgccgt
    10381 cgtcgtcgac gaagaggttc gggtcgatgg cgttgtagtc gctggaggaa ctggacgtgt
    10441 agacggtgcc gtagtcggtc cagctgcccg gctggccggt ggtggagccg gcgagaccga
    10501 tggcggacgt gttcgagccg aacttcgaga cggagtagta catcaagtac ttaccgccac
    10561 ggaacgaaat gtccggcgcc caggcctccg gcacggagga gtacgtcgac caccagcccg
    10621 gccgaccgga gaacgcgtcg gcgccgttcc ggaaggcggt gcgatcggcg gagaccttgt
    10681 tggcgatgcc gccgccggtg gcgtacagca ggtactggcc ggaggaggta cggatcatcg
    10741 tcgggtcgtg ggtgacgatg tcgccggtga cgcggccggg gttggggtag gccgaggcgg
    10801 aggtgggggt gagggcgagg agtgtggcga gggggagagc gaggagggtg gtgcgcttgc
    10861 ggctcatgcg gtcctccttg cggtgggggg agtaacggag gcgggttttc aggctgctcg
    10921 acgtcgtccg acatgccgaa caacgctcgc aagttcgaac ggaccgtaga atcgaacccc
    10981 ttgcgcgtca atggcccgcg cagcaacagc cgcgtcgccg atccgaacgc gcttgcccgc
    11041 agcggccgtt cgaagttacg ttccctcggg ttccgttcga acgggggttc tcgcctcacc
    11101 acggcgggac acccggatcc ggccgttcag cagccggaac tacgccgcat caatggacag
    11161 ggaatgcctc agctcgtcaa tcgcggaatg atggaatcgg cctttccacc caagaaggtc
    11221 gtcagagtga gggaggacgg gctccctgcc tgtctccatg agtcggccca cgtgatcctg
    11281 accgacgtcg gcctgccgga cgaccgggct tcctttttcg cgatcgacgg agcgctcttc
    11341 gagggcgaga cgcccaatag ctttcggcga tgtgcggagc tcagctactt ctccgcctac
    11401 aagaacatgc cgaacggctg ggagaactgg ctcgtcattg gagagatctt ctacgactgt
    11461 gtggtcctgg accccgtgtc cgggatcgtg tactgcctgc cggacggcga gtaccgggca
    11521 gacccgctga accagagcct cgactccttc gtctacttcg tctacctact cgaactcgag
    11581 cgccccaact acgacttcac cgtgtcggac gagatccccg actcggaggg cgtggccgtg
    11641 ttcctgcggg agaggatgat ccgggtcgac ccgctgccct tcgaaggggt ggagccctcc
    11701 tggtcggagg ttttcgactg ggaggccgag gacgcgcctc ggatgccggc gtgggatgtt
    11761 gttctctcga acgtgtacga gtccattggt taggctgagt catccatggc agtcccctac
    11821 ttcgtcaccg ccgagtccga ccccgtcccc ctggaggact tcgcgaagtc cgtggggcgg
    11881 gcggtcgtgc gggaggagtg tcgggagtgg gcgcgtctcg gtggtgaccg ggggttcgag
    11941 atctgtgctg atcacgacgg tgtcgtgcgt gccgtactcc tcgactggga cgaggacttg
    12001 aggttcgtga gctcggcgcc ggaggcattc gtcgagtcgc tcgccgcgct cgaccgagcc
    12061 ctcgccgtga tcctcggcac cgactcgccg caggaggccg ccgccgcata cggggagctg
    12121 gagcggcgat tgcaggtcat cgacccccag gccttcgcgg ggcgcgagaa ctggtggccc
    12181 ctcgttctcg acgacatcag ggacacggcg ggcgcggagt ggttcaccgc gttcgagatc
    12241 gtcgacgagc ggggcgagaa gcagatcgtc acgcaggccg gcgggatcgg tgtccatccg
    12301 gaggagcggc tgtgggggcg gctgcgggcc gcgggggtcg ccgctgagca agtgctgcgg
    12361 atccacaccg agttggaagc ctgcttcatg ccggggcact actgctcgct ctggctcggg
    12421 caggtcttcc ccgatgcgca gctgacgcac aacttcccct acggtgagac tgccgagtcc
    12481 cgtgccgagg gcatccggtt gctgcgtgag gcggcggagc aggcgccgtc ccagtagggc
    12541 cgcgggagtt gagggaagag ggagcgcagc acgccatgac cgtcggtgcc gccgtaccgg
    12601 acatctcctc ctggccgccg ttggacgacg acaagcgggc cttcgggcag cagttgctcg
    12661 gctgggcggc cgacggcagc ggggccgggc accggctgtg tctggtgcgg ggtgccgagg
    12721 gcagcgggaa gagtcatctg ctcgcctggt tcctggccgg agcggccggc agcccccgca
    12781 cgaccgtcca cgccaccatc ctggccgagg ggctgacggc cgacaccttc gcctgggaac
    12841 tggggcgcca actcggctac ggccccctct cccccgcacg gctgctggac cgggtgagcc
    12901 aggacgagcg gccgctgctc ctcctcgtgg tcgatctgca ccggtccggg gcaggccccg
    12961 cggatctgcc gacggcggca ccggccacgc tggtcgccgc cctcctggag cccctgctgg
    13021 ccctccccca cgtgcgcgcc gccgtcgaga tcggcgacga cgaccacggg ctgctgtccg
    13081 cagacggtgc cgacatcatc gacctgggcg gcgacggtgg ccgtgggagc gccggggaga
    13141 tgtcgttcgc ggagcttgcc gccacggttc cgcgcacggc cgacgggcgg ccggactggt
    13201 cgcgggcacc cgccccctcc ctccgccaca tcctcgacgc tgccctgcga gccgatgacg
    13261 aaggcgccgc cgtgcgtggc ctgttggccg acccgggctt cctggtgcac ggctcggcga
    13321 acgccctcac ggccaccctc gccgatgagc gcatccccgt acccggtcgg ctccgcgagg
    13381 tgtggcagcg cgccgcaccg gagctgacgg cacatcacga cgacagcgcc gagcgtgccg
    13441 ccctgctgca cgccgccgcc gtgggcacgg acgcggccct gtccgagttc ctgcgtcccc
    13501 tcgcccgacg ccactggtgg tccgcggtgt gggccaggcc ggatctcccc gtcgccgcac
    13561 tggcaccggc gccgggcgac gaaccacgcc tgttgacggc cgacgtcacc ggacggatcc
    13621 ggacgtacga cacgggcacc ggcgccgcag ccggagcgac cggctcaccg ccgtccacgc
    13681 gccccgtcgc cgtcgctccg cgcgacgccc acgcgatgct gttgctcgac cagaccggcg
    13741 tgctgctgcc gctcgcaccc gaggacgatc ccatcgccgg cttcatgctc gaccacatcg
    13801 ccgagcacca cggtgcggcc gccctcgccg acgacggtgc ccaggtcatc gcactcggcg
    13861 gcggcagccc gcagagcccg tacgcgatcg tcggcgaccg cggcggcaac ctccacgcat
    13921 ggtccctgag cgactatcag gactccccgc tctcctgccg cgtacatgag ctgccggtca
    13981 ccgccgccgt ctgcctccgt atccccgccg atgatctgac aatcaccttc agcgcggcac
    14041 tcgacggctc ggtacgcctg tgggagacct cgggtgaacc catgccggtc cccgtggagc
    14101 agcgcgcgtc ccaggtcacg gcactggccg cggccgacac ctccgtcgga ccggtgctcg
    14161 ccgtcgcctg gagcgacgcg gagttgcacc tgtggcacgt cctctccggc cgaatgcgcg
    14221 cccttcccct gctgcacggg tgcggctcac tcgccctgac acccgagggg ctggtcctcg
    14281 tcggaggccc cgaggggttg tacgccgcgc gattgcggct ggacgggctc tggccctaga
    14341 tccggtgaag cgggagtcgc acgaagccca ggatgcgtgc gcaggctctc tcccgaagac
    14401 cccggcatca tcgtcgtccg tgactccaag gccccggaga agcgtcggct cgcggtgtcg
    14461 ccggaggcgt ggggagcctt cgtgtcacat gcctcaaggt gaggtcctgg ccggtacggc
    14521 cgtccagcag cgccctcccg agcggcgtca ccgtatgcac cttgcatgaa ctgaccagcc
    14581 ccgccttccg caggaccccg acgtggtggc tggccgtggc cagggagacc cccgtgccgt
    14641 gggccagctc ggtcgtcgtc actccccggg ctgccaggga ctccaggatc acggcgcggg
    14701 tgcggccgag gagggcgttc agggagcgcg cctcgggttc ccggtcgccc agggccgtct
    14761 cgtgggtcat cgggtagacc accacgcacg ggagcgccgg atccttcagc agggtcggct
    14821 tgcgccagca gaagtaggag gggaggacga ggagtccgcg gccgtccagg tggacgtcgc
    14881 ggtccgcgcc gagtcccgtc acttccagta ccgggcggtg ccagagcagg ccggggtgca
    14941 gggagccgag cagggagcct aggccgccgt cgaccaagta gcggccgtgg acggagcgtt
    15001 cggcgtcgaa gcgggagcgg atgcggggcc accagggggc cagggcggtc gcgaagtagc
    15061 ggcggagggt gcccgcgaga taggtcaccg tctccttgtc gccgtcggcg agctgtcgcg
    15121 cccggagtgg gagggggcgg cccgtccggg acagttccgc caggtcgccg cgaagcctcc
    15181 ggcggggtgt ggacagcacc gcgtcgatcc cggcgtccag gccgtccgcg ccggcggccg
    15241 gggtgaggaa gtcggccgaa tagccgagcg ggggtgccag gcgtagcaac tggcctacat
    15301 ccagggagag ttggtggcat accgtcctcc gccaggcgcc gaagaccgcc gatcccgtgg
    15361 tcgtctgcag catgtgcatg ctgagcagcg cctcccacat ggggtcgggg gcctgcgcca
    15421 gcctgatgtt cgcgaggtcg tcgtcggtga ggtgaatgcg taccggcata tgagccatcc
    15481 ccgttcgatg catgtgcagt cacatgctcc ggggggtgtc ggctcctgcc atcctcagaa
    15541 gtctcagcgg tcagggggcg cccggtgcgc gatggtgccc gaacatgacg aacgcgccgc
    15601 ccttgtcgtc gaccgtgttg ggtacgaccc ggtgctccgt gccgagcaga tggcccaggt
    15661 cctccctgaa gagcagcgct tcgatcaggc cccggtcgcg ggcgcgcgcg gtgtcggcga
    15721 accatagccc gacgatctcg ccgtcccgtg tgcgcaccct cgcgtagttg ccgttgtcgt
    15781 gctccacggg ggccgggccg gggcgctggc cggggaccag gtcgtcctcc gtgagggatg
    15841 ccgagaggag tacgcagccg tcgttgcctg cgctggcgac ccgggtggtg ccgtcggggc
    15901 aggtgatgcc gatgacgtcg ttgatcgtcg cgctgccgaa ggacgcgtcg ccgaatgcct
    15961 ggccgtggcg gttgaagggc ggggtgaggg cggtcgggtg gtgcgggtcc cagagctgga
    16021 ctccgcactc gtcgtagacg cggaacgccg cggcgatcac cgtacggccg cccagcggga
    16081 cgggcgccag cacctcgtag ggggtgtcca gctcgccccg ggcggtgtgc tctccggtcc
    16141 gcaggtccca tacgtcgatg ccgcggccgg ccgggatcgc gaggtggctg ccgtatgccg
    16201 tgaagtcgcc cggaccgcgc gccatgaggg agaaacgccc ttgatgccag ccgcgccggc
    16261 ccggcgccca tacctccagt ccgccgccgt accgggccgc cgcgaagccc cccgtgtcgt
    16321 cgtccgggcg gacgccgacc agccggcgga cctggtcgcc gatgtgaccc ttcggatgcg
    16381 gcggctgacg gaagccgaac acctcctgcc cgcccgcagg gtcgatcacc ctgaccgcct
    16441 tgccgtcggc gaccacgagc agctgcggtt cgcccgggac gaccgccacc gccgaggcac
    16501 cggtgtcgac cagccgacgt ggggtgtact ccgggctgct catatcgcgc gggtcccaca
    16561 gcgtgacgcc gtcggcgccg gcgcacacca acgcccagcc gtcggtgccg aggtcgaccg
    16621 cggccaggcc cctcacgttg gcgctgtcga cggtgaccgg tccggcgacg tgctcaccgg
    16681 tggcggcgtc ccacagcagt acggcgccct gggtgtcgcc gctggccagc agctcgccgt
    16741 cggcggtggg gacggtggcc aggtgcatca cgatcgagct gtgcccgcgc agttcgtact
    16801 cgccgttcgg gcgggccgtg ctgccggggt ccgggcgctt cggcggtgcg gtgggccggc
    16861 ggcgccggaa cgggttgggt agcttcatac ccgtttccta gcaactcccc ctcgggaccc
    16921 gtccccggcg gcgagttcca tgactcgcat agaacttgac ggatcctcac tttgcccaac
    16981 tgacagccca tcaacagcaa gcctccctac ggtgccgtgt ccatgacaga cacctcacga
    17041 ggcacctcgg aaaacaccga gaaggaaacc ccgttcacga tcggtcgccg caccgtactg
    17101 atcgccaccg gcgccaccgc cgcggccctg accgtcggcg cggcggcccc cgaaaccccc
    17161 gccgccgctc aggccgccgc agccgtctgc accctcacca aggagatgac cgaaggcccc
    17221 tactacctcg acggacagct cgtccgcgcg gacatcagcg aggacaagac cggcatcccg
    17281 ctggagctca ccctcaccgt cgtcgacgac gacacctgcg cgccactgga caacgccctg
    17341 gtggagatct ggcactgcga cgccctcggc gagtactccg gcttcgtcgg caacaacggc
    17401 cacgacgaac ccgacaacgg cactttccta cgcggcggtg tcctcaccgg ctcggacggc
    17461 gtcgcgcgca tcaccaccgt gtatcccggc tggtaccgcg gccgctgcgt ccacatccac
    17521 gtcaaggtgc acaccgacgt cacgctcacc gacgacggct cgttcaccgg cggccaggaa
    17581 ctccacaccg gccagctctt cttcgacgag acgatcacga cccgggtcgc cgcactcgcc
    17641 acctacgcgg ccaacaccgt cccgcgcacc accctcgccc aggacggcat ctacgacgac
    17701 ggaggcgccg cgtccggact gctgacgctg accgcgctgg gcagcacccc ctccgccggc
    17761 tacgcgggga cgctcacgct gggcgtggag agctgacgta cacctggagg acggccgggc
    17821 cgcgacgagc gtggcccggc cgtcgccgta tcactacttg gcgccggggc actccttcca
    17881 cgccaggtgg tagacggtgc tgatgtcacc gtcggtcgag tccatggtca tgaagctgac
    17941 cttgctcgcg gacgacgtgc cgaggttcac ccgcagctcg gtgttgatgt tgaagttgcg
    18001 ctgcttcccg cagggcgccc agatcagctg ggcccagtcg gtctcgtcgg tggcctgcca
    18061 gttgtcgttg agcgggccgc tgaacgcgtg gttgcgggac tgggtgtccg gtgaaccctg
    18121 gaagtagtac gacgccttct gcgtggcctt cgcgccgggc tggagggcgg cgaagccgcg
    18181 gtagtcggcg ctggcgatgg cgtaggtgaa gccaccgggg acatgcacga ccaggctgag
    18241 ctggcagttc ttgcggaacg ccgtcgggtc ggagttgccg ccgacctggg cgaggtagtc
    18301 gctgtaggtg acggtgaacg cggtgttgtc ctcggagacg gcgacggcgg tggtgcccgc
    18361 ggggcagccg gagccgttga ccgtggcgac cttgatgacg atcttgtccg gcggcgggtc
    18421 ttcgaacgcg ggggacgcct gtgccggcag ggcggtggtg aggagggcgg ccagcgcgcc
    18481 gccgctcagc agcacgcgca caaggccacg tgccatgggt ctctgtgcca tggatctctc
    18541 cttgggatgg ggggtggctt cgccctcctc atgaacctct tcgtgacccc tttgaggaaa
    18601 cggtgaggtt tctgtgagga tcgagggcgt tcgcatcgta gggagcggcc agaaccgcag
    18661 ccagggtgaa ctccggccat ttacaacgca gttgggcccg attgagcgat gcgttcccag
    18721 gccattcaca gccgcacatc aaggcgctcc tcaactaccc ttctaatttc cttcacatga
    18781 cgggaaacca agagcacgac ggtcgccgtg gcgggcggcc tggcctcggc cgacacgacg
    18841 acaacagcca cgaggaggag gacaacggca cctccctgcg cggcggccgg atgaccgacg
    18901 agagcggaca gtgcgacatc acctcgatct ggccggggca ctacgtgtcg cgcgcggtgc
    18961 atgtccatat gcgagtgcac acggacgtga cgctcaccgg cgactcgtac acaggcggcg
    19021 agatcattca caccgggcag ctcttcttcg acccggacat cagcacggag gtgcagacga
    19081 cctcgccgta cgcgaagaac accacgccag agacccggtt ggaggacgac ggcatctacg
    19141 acgactcagg cgcgtcctcc ggtctgctga ccctggcggc actcggtcac agcgtgtccg
    19201 acggctacaa ggcgaccttg acagtgggcg tcacctccga ctgagcccgt aggacggtca
    19261 ggaagccggg ccgagcaggc gtttggcgcg gtggggggag gtgtccagct tggcgaggac
    19321 gccgacgctg gcgacgttgg gcaggatcaa ctggtacagc cgcgctatct cctcgtccag
    19381 gcccgggccc tgtggccgcg cctccgtcac cagttgcaca ccggtccagg cacccacggc
    19441 cagccgcgcg atctcggcgg ggaccgcgtg cggcagcaac tcgccgcgct gctcggcctc
    19501 gacgagcagg tcctcgccca ggttgatcca gtccggccag cgggtgccga acatgctgcg
    19561 cgccttgggg tcgacggaca gctggacggc ggcgcgcagc atcggctcct ggggcatccg
    19621 gtgggcaagg aggaggccga ggtcgaccca ttcctggagc ttgtacgtct gcgggaggat
    19681 cccctcgcgg gtcacggccc cgtcgagcac gccgcgcgcc atcgcttcct tggtcgggaa
    19741 gtggaagtac agggcgcccc gggtcagccc ggtccgctcg acgagggccg cgatggtggc
    19801 ggcctcgtag ccgacctcga tgaagaggcc ggccatggct tccaggatgg actcacgcgt
    19861 acggatcgca cgctcctgac gtgccactcg gccgccctcc agtctcttcc caggccctgc
    19921 cggaacgttg aaccgtcgac catgggctac cgaaggttcg gaatggtacc aagcccttcc
    19981 ggccgtcccg gcaggggaga tcagtgtccg gacccggtcc ccgccgcgct cgccatcagg
    20041 ctcttcagat cccgcgcgta cttgacgacg aggtcacggg tgaggctcgg gatgtccccg
    20101 tgtccgtccg cgccgtcggc gcggacggcc gcgcggaacc gctcggaggg gatgacggat
    20161 ccgggcaccg cttcctcggg ctccttgaag ccgtgcagga tgggcagcgc cgtgtactgc
    20221 cgcagtgcct cgggcagggc gcgcatcgcc gcctcgaacc ggacgtacca gtccgcgtgg
    20281 tccgccaccc gctcgatggg gtggccctcc tggaccagcc agtcgacgaa ggtgtcgagg
    20341 gagacgccgt cgtcgttcgg gttcacgagg ccgaacgtcc ggtactcgga cgggtgccgg
    20401 ggcgcgccac ggccgccgag ggcgaccacg gccgcggcgg tgaagtcgac cggcagtccg
    20461 tcgtagtggg ccttctcgcc gtccgcgcgg tagaaggtgc gcggcgcgat gccggtggcg
    20521 agcacgctga acagcagtcg gctgaacatg tcggggacgt tcagctgtcc gccgtaccgg
    20581 ctgtgcgcga ggatcatgtt ggagcggaac gtggtgaccg gcagtccgca caggtcgtgc
    20641 gcctcgcgca gcagtacctc gccggcccat ttgctggtcg cgtatccgcc ggcgtagccg
    20701 ccgtcgacgt cctggaccgg catggcgagg cgggggtcgg tgtcctcgtc gagggcgggc
    20761 tgtccggggc gtgcggtggc gaccgcgacg ctggagatgt aggtgaccgg cttcatccgg
    20821 ctggtgaggg ccagctggac gagttcggcg gtgccgacga cgttggcctc gaagaggtgc
    20881 gggtagggca ggacgtggtt gaccagcgcg ccggcgtgga cgatcaggtc gacctcgtcg
    20941 gccagccggt cccaggacgc ctcgtccagg ccgagccgcg gctcggccat gtcccccgcc
    21001 acgacgtcca gatggtccgc ggccagttcc tggtacgtcc gcaccagttc cgggtcgccg
    21061 ctgtcgaagg cggcgtccag ccggcgccgg gccgcggcgt cgtccttccc gcgcaccagg
    21121 gcgatcagcc ggccgccggc cggtgccagc gtgcgcagcc actccagggc gaggaaacgg
    21181 ccgagatagc cgctcgcgcc ggtgagcagc acggtgcgcg gttcgccctg cgggcggggc
    21241 agtgcctggg cgtcggtgag gaggcgggcg tcgatgaacc tgtcgagggt gaggtccttg
    21301 gcgtggacct cggtcgcgcc ctcgccgtgc accgaggcga acgtgggccg ccgctcggtg
    21361 gtgccgcgcc gggcctcgat gtgctcggcc aggtgccgca ggtcgtaggc ggggctgatg
    21421 accatgtcca ccggcacccg gacgccgaag gtgtcctgga gcaggttcga gaaggagacc
    21481 gcggacagcg agtcgccgcc caggtccctg aagtgcgcgt ccgggccgat gtcggccatg
    21541 gatccggcga gcagcgcacg tgcggcgcgc tgcacggtct ccagcaccgg ccggtccgcg
    21601 ccggagaggc ggatcgccgc gagttcctcg tcctcgcggg cggtcgtgtc ggcgtacagc
    21661 gcgtcgagac gttcgccgta acgttccgcc aggcggggcc acagcagctt gcggtggtcc
    21721 gagagcaggc cgttggcctg gctgaacggt tcggtctcga tcaggaagtc acgcgggatc
    21781 tcgtacgagt tgagaccggt ctccttggcc agctcctgga gcgtcccgct cagccgctgc
    21841 ttgagggccc gctcgtcccc gtcggactcc cgcagcgcgt cgggggtggg cacgacgacg
    21901 gctaggaggt aggaccgctc gctgtcgccg tggacgaaga tctgccgcac cagcgggctc
    21961 gcggcgaaga cggcctccag ccgggagggg gcgacgaact cgccctggga cagcttcagt
    22021 acgttgccgc ggcgggccag gatggcgatc cggtcgggct ccagctccgc gacgatgtca
    22081 ccggtccggt agtagccgtc ctcgtcgaac agctccgcgg acagctcggg ctgccggtag
    22141 tagccgggga cgacggcgtc ggaacgcagc aggagttcgc cgcgcgggtg cggcagatcg
    22201 gtgcggaagt agccgagttc gggtacgtcg gcgagcttgt agtcggtgac cggcgggcgc
    22261 agcagcaccc cgtctaccga gactccggcg gcctcggtgg agccgtagac gatgtgcagg
    22321 tcgaggccca gcagggactc gatgaacgcg gtcagttcgg tcgagagcgg ggcggagccg
    22381 gagctggccc aggtgacccg gccgccgagg acgttctccc ggatgtccgc gcgcacctcg
    22441 gcctcggcct ccgcgcggtc ggtgccggcc gcggtgcgcc gctccacctc gctccggaag
    22501 cgctggtgga gcatctcgca cacccggggc accagggaca gttccgtggg ccgggcgagg
    22561 gcgatgtcct cgaagaacgt cgacagatca ctgccggccg tgaagtaact ggcgccgccg
    22621 cgcaccatgg tggccttcag cgaggagtgt cccgccacat ggctcatcgg catgtagtgg
    22681 aaggtgacgg cgtacgactc gtcgaagagc ttcgcccagg cgccgcccca catggcgccg
    22741 gccagccgct cggtgtacat ggcgcccttg ggcgtaccgg tgcttcccga ggtgtagatg
    22801 agcatcgcca gcgggtcctc gccgtcggcg gcggtgaaca gcggggcctc gggcagggcg
    22861 gcgccccgct cgatcaggtc ccgcaggatg tccacgacca cggcggggcg ggcctcggtg
    22921 aggcggtcga gggccgcggc gagggtctcg cggtggtcgt ccgcctcggg gtggaagtcg
    22981 aagaccacca gtcgccgcac cgagtcgctg tcgcgtatca ggtcgaccgc ggcgtcgagg
    23041 cgctcaaggc tcgcggccac cacgaacggc tcggtctccg ccatgatcgc ccgcagctgc
    23101 gcgggggctg cgctggtctg gagcgggacg gtgacggcgc cgagatggat gcaggcgagg
    23161 tcgacggtgg cccagtcgcg gctggtgaag ccgaggacgg cgacccgctc accgggcctg
    23221 agcgggtggt ccgggcggtg gtgccattcg ccggcgaccg ctctgacccg cgtccacagt
    23281 tcgcggtagg tggtcgtctc gtagcggggc agcagccgga tcgagacccg tcccgtggcg
    23341 gagtcacgcg cgaactcctt cgcgcgttct ccgacggcgg ggcggtccgc gtggcgttcc
    23401 atgacggatg ccaccagttg cgcaagtcgc attctgagtc tccgcgtcgc gtgttccaac
    23461 tcgtcacccg aaggtagaca cagcggacgg gatccctgag gaatcggtcg acgatctgtc
    23521 aggtcaccga ccggctccgg ctgcctcgac atgccgggtg cgacatcgcg ccactgtcag
    23581 taactcttcg tacatggtgc gttgtcgacg tggtaagagt ggaggactct cggggcggaa
    23641 gcccgctggt ccgcgcgccg tcccccctct tccttctccc tctccggagt gcgcatcgtg
    23701 atgcaggacc gtgccgcaag gacgcgacga gatttgatcc gatccgcggc cgagctcatc
    23761 gaacagggcg gattcgccgg agcctccgtc gggcagatat gtgccctggc cggggtcagc
    23821 cgcggcgccc tgcacttcca tttcggcaac aagcaggccc tgggcgaggc ggtggagtcg
    23881 accgccgccg agatcctgct gtgtgtgacg gggcaggtcc cggagcggca ccccgcaccg
    23941 ctgcagttcc tcgtcgacac ctcgcacacg ctcgcccagc gggtggtgtg cgacccggtg
    24001 ctcagagcgg gattcaccct ggcgcacgac gcggcctggc acagtgacgt gagcctgtgg
    24061 cagcactggc ggcagtgggt gcgcgggctg ctcgacctcg cccggcggca gggcagtctt
    24121 gctcgcgacg tcgatctcga cggcgcggtt tccgccatca ccgcgctgat ggccggtctc
    24181 gaggggctgg agcgcgatcc ggcccgcgac cggatcgccc gctcggtgac gccgttctgg
    24241 cgtctggtgc tgcctcagct ggccgcggag gcggtgcggg gccggatcga ggcggcgggc
    24301 agctccgccg ccatggccga cgaaccgccg ctggagcgct ggcggttgga cgacggggcc
    24361 gccccgcacg aatgcgccgc gatgtccgac gcggagctgt gctgcgtccc ctacagggag
    24421 atgagcggct ccgcctcgta ggcccggtgc agcaggtcca ggaaagccgg tgcctcgggc
    24481 agggacgtcg ggccgatacg gcggacctcg acgcccggcg tccatgagtt catgaccgcc
    24541 ccgcccgcca gtgccggcag atccgcgggg gtgacctccc gtacgcgctg ggggacgccg
    24601 aggcggtcca gttgcctgcg gacgacgccc atcgtgaccc cggccagcat cccggccgcc
    24661 ggccacacca cggcggtgcc gtcccagaag gcgaggttcc agatcgaggc ctcgctcagc
    24721 cggccccggc ggtcggtgaa cgcgacgtcg tcgcagccct gttggacggc ctggcgcggg
    24781 aagtaggtct tggcgggttc gccgacgtgc ttcacggacg gcaggaaacg ctcgtgctcc
    24841 acgaccgcga gggtgagcgg gcccgcgggg ccggtggccg gtggtgcgcc gcggaccagg
    24901 agttcggggt cctcgtcggg tccggccacg gtgaactcgc cggacgggga gtagacggtc
    24961 gcggtcagcg agaggtcggc gggggcgtcg tccagggcgg cgcgcagcca ggtccgcacc
    25021 cggtcgtcgg gcagtgcccg gccgaacagt tcgagcgagg cgtgtcgcag tcgggcgaga
    25081 tgcagatcga ggccgcgcac ccggccggca cggatctgca tcgcggtgaa gtgggcgtat
    25141 ccggcgaagg cgagcggtgc caggtccgcc acgccggccg tgcggtcgtt gcgcctggtg
    25201 ttcatcgaat gggcagtcgt cacgccctgc caacgacccg gctcccgggc ggacacctcg
    25261 gaaacgtccg gtgggagccg ggagttcgct cagcgtggcg cggtgaccgg aaaggtcctc
    25321 gtgaagggcg tgtcggcgtc gtccgaccgg tgccgcgcgg cgcgctgctc cattccgtcg
    25381 agcagggtct ccagacccag gtcgaagtcg tcctcggtcg cccgcagcgg ggactgctcg
    25441 ggcttgtcgc ctccggacag caactgctgg gccaggtgct gaatgcacac gccctgcaca
    25501 tacgaccaca cggcgatgga gaaggaccgc gcgaggtcgg gatcgtcggt gaggtccgcg
    25561 agggcgtcca ccatccagtc gaggcaggag gtgtccgaga aatgccgggc ggaactcgag
    25621 gtcaccagcg cccaggggtg ggtgcagtac acctcccagt cgagccgggc ggcgagccgc
    25681 atcgcctcgc gccagtccgg gggcgccggt tcgggatagg ggtgttcgtc gcaggccgcc
    25741 cgggtgatcg cggtgagcaa cgtgtccttg ttggccacat gccgatagag cgacatgacg
    25801 cccgagtcca actcggtcgc caggcgccgc atcgagagcg cggcaatgcc ctcggcgtcg
    25861 gcgatacgga ccgcggctgc cacgatcgcg ccccgcgaca ggccgcgtga actcacttgc
    25921 ctgccttgtg ctttgaaggt catggggtag tatacccagc agcttgcgta cgccgtacgc
    25981 atgaatttcg cgtacaccgt acgcatggaa tagcgcgtac accgtatgca gggtttcgcg
    26041 tacaccgtat gcagctttcg gaacttcttc gcaccttctc ctgaaaggtt gcccccgtga
    26101 cttccctcga cttagtcgcg gagcgtgccg accgacgggc ctggctgggc cttgtcatcg
    26161 tgctcggccc ggtcgcactc gtcgcgatgg acggctccgt gctctatctc gcgatgccga
    26221 gcatcacgtc cgcgatcacg cccagtaccg accaggcact gtggatcctg gacatctacg
    26281 gcttcgtggt ctcgtccctg ctcatcgcat tcggcaacct cggtgaccgc tacggccggc
    26341 tcaagttcct ggtgaccggc gcggtcgtct tcggggccgg ctcggccggt gccgcgttcg
    26401 cgccgaaccc cgagatcctc atcgcctgcc gtgcgttgat gggcctcggc ggcgccacgc
    26461 tgctgcccgc cggactcgcc atcatcggca acctcttcca caacccgaag caacgctctc
    26521 aggccatcgg catcttcgcg gcgaccttcg ccgccgggtt cgcggccggt ccggtgatcg
    26581 gcggtctgct gctgagccgg ttcgactggg gtgcggtctt cctcatcaac attcccgtcg
    26641 tggtgctgtt cgtggtcttc gcgccggtgc tgctgcgcga ggtgcgcacc tccaatccgg
    26701 gtcgggtcga cgcgctcagc gtggtgctgt ccgcggtcgg catcctgctg gccgtctact
    26761 ccatcaagac ggcggcggcg gagggcttct ccctctccca gatcgccatc ggggtcgtcg
    26821 gtgtcgccgt cctggtgtgg ttcgcacgcc ggcagctcac gctggagtac ccgctgctcg
    26881 acctgcggct gttcaaggac cacgtcttcg ccgtcgcgat cctcaccggc ctgctctcgc
    26941 tcgtcgcctg ggccgccgcg ggctatctca gcggcatgta cctccagtcg gtcctcggct
    27001 acagcgtcct tacggcggcc ctgctggcgc tgccgggtgc ggcggtcctc accgccgcgt
    27061 gcatcggggc gagcggtgtg gtggaccgga tcggcaagcg gtcggcgctc atcgcctcgc
    27121 acttcttcat gggcttcggc ctgctgcttc tgctgctgac cacgaccgag cacggcgtgg
    27181 cggcgttcat cgcgtcctcc gtggtcaccg gcgtcggcta cggcttctcc ttcagcctgg
    27241 tcgcggacac cgccgtcgcc gcggtgccgg ccgagcgggc cggttcggcc gcgtcgatcg
    27301 ccgagaccag caacgaactg ggcaacgccc tcggcatctc gctgctcggc tcgctggcgg
    27361 ccctcctctt ccggctgacc ggccccgatg cggcaggcac gctcgacgag acactggaca
    27421 cccgcggcct gtccccggcc accgccgaag aggccaagga ggccttcctc accggtctgc
    27481 atgtagcggt cggcgtggca agcgccctct gcctggccct gggcatcctc gccctgcgct
    27541 gggtacccaa ggaggagaca ccgccgtccg agcccacccc ggacccggag tcgatgacgg
    27601 caacacactg acccaccccc ccttacggcc ctgcggcccg gcccctgacg acaggagcgg
    27661 gaccgcgggg ccgaggcatt tcgagcggac ctcacgcggg gccgcctcgg gtgccgagtc
    27721 ggcgacgacg acacgctcac ccaaccttcc ggccctgcgg ttcagctcca ggagagagga
    27781 gcgggaccgc agggccgagc gtttccagcg aaccccgcgc ggggccgcct cggatgccga
    27841 gtcagtaacg gcgacacacc acccaaccct ccagccctgc ggcccgaccc ctggcgacag
    27901 gagcggggcc gcagggccga ggtgtttcca gtgggcccag gtgtcgttcc ggtgtcagtc
    27961 ggtcgtgccg aagtcgacgc ggaaggccgg ttcgccctgc tgggttccgg tgactcggac
    28021 cgcgccgggg gtcggtagtg gctcggtttc gagccagcag ggctggtcga attcgacgta
    28081 gcgccagtag gtggcctcga tcgtggtcga ggtgaagggg gtcggggagt gcagggtgtg
    28141 ggccgcctgg tcggcggcct ccagtagggc caggcccggg acatggtcga cggggtggtc
    28201 gaagaggagg tggttgccgg ggtcgttgcg caggaggagg cggcctgggc ggtctccggc
    28261 ggacagcgcc acgtcggacg gtccggctcg ccctgccagc cgggcgtcca ggggcgcggg
    28321 taccggccag gatccccagt gcacgctgcg ccgggtcccg cggaggcggt cgtagacccg
    28381 ctcggagatc caggtgaact cgctctcggc gcgggccagc ggctccccgt cccgcagcac
    28441 ctggaaggtc atgtgcagcg cggatgtcgt acgccgcctg cccccggcct ccgaaacggt
    28501 gacatggacg tccagcgccg aggtccggcc acggggtatg cgaaggcccg gggcgatgcg
    28561 gaaggagagg gtgctcagca tggtctggtg ggtcagcgga acgccgtact cggcgtgggc
    28621 gacgaccagt ccggtctgcc ggatggtctg ggcgaggatc cgcgggtcgt agggcaggtc
    28681 gccctggacg gccggccatc tgacaccgag ggcgaactcg ccggcggcca gccgtcgtga
    28741 accggtgacc agcaggtact cctcgcgtct gaggtgggcg tacgagctga gttgagcgga
    28801 tgaggccgtg ccgggtcgtg gtgcgagagt ggtgtgcttc aacgttcccc cagagtcgaa
    28861 ggtggtcggt ccgcgctctg tgctctgtta aagtaccgga cctccgttcg gttatgacca
    28921 agggcaagcg tgaacccaag cacagctaaa gggagttgcc cggaaggtgc tcgcatggga
    28981 aggcagcaac gagccgtccg cacccggagg gtcatcctcg aagccgccgc cgcgatgttc
    29041 aacgacttcg ggtacgacgc caccaccatc ggcggcctca tcgagcgcac ccggctcacc
    29101 cgcggcggcc tgtacttcca cttcgcctcc aaggaacagc tggcgcgcgc catcctcgac
    29161 gagacatcgg ccctgcgacc cgtcccgccg cagccgctca agctgcagga atgggtcgac
    29221 atggccctgc tgctcggcta ccgcctgccc cgcgacccgc tgctcggcgc cacggtccgg
    29281 ctgtcggtcg acctcagggc gcgcgcgttg ttcggcaccc gctggcccca atggacggac
    29341 gcgggcgagg agttgctgtg cgcggcccgg gaccggggtg aactgctcgg ccatgtggag
    29401 ccggccgagg tggcgcggct gctcaccgct tcctgggccg ggatccggct gctcgacgag
    29461 gccctgcccg acggcgaact ctgcacgcag ttcgccgtgt tcctggagct ggtcctgccg
    29521 aacatcgcct gcccaggggt actggcgaag ctggacacct cgccgcaccg ggccgccgcc
    29581 ctcgaccgcg cgacctgagg aaaattcgcc gccgtctcgt gcatgcttca tatagaaaca
    29641 ggacgacagt cctttttcat agacggggga acgggggaac gggatgcgcg acggcctgga
    29701 cgacggggca gcggcgggcg aggggccgat accggacgtt ctggatgcgg agctgtgccg
    29761 acggctgttc ggttcgctgc accgcagcgg gcagcgggtg aaggccgaac agtacgtccg
    29821 cgggctgctg tcggtgcgcg gccgcaagac gctgcggagc atcgcggcac agttcgacgg
    29881 ggcgtcggca cagcagaacg tgcatcactt catcgcctcc tcgccctggg agtgggtccc
    29941 cgtacggcac gccctggccc ggcaggcgca gcgggccctg gcaccgcagg cctgggtgat
    30001 cgactcgctg ctgatcccca aggccggtcc gcactccgtc ggcgccgacc cgcagcccac
    30061 cccgctgggc accgtcaacg gccagcaggc ggtgggcacc tggctcacgt cggagcgggc
    30121 ggccgtaccg gtcgactggc agctgcggct gtccgcgcgc tggacggtcg agccgctgcg
    30181 gcaccgggcg agcgtcccgc cggacgccgt gccgggcacg gtggaggaat gcgtacggca
    30241 ggccgtggtc gggctgatgg gcgtcgggga gatgccccgg ctgccggtgg tggtggacgt
    30301 cgcggaggcg gacggcatct cgatcgcccg cttcctggcg tcgacggggc tgccgttcgc
    30361 ggtacgggtg gacgcggccg cgcccgtgcg gatcgaccgg tcgctgctgc cgaagtacgg
    30421 cgatctcctg cacaccgcag gcgagttgag cgagtccctg ccgcatctgc gccagcaggt
    30481 caaccccggt gacgggcgta cgacggccgc ggcgatcccg gtgtcggcgt caccgtcggg
    30541 gcgggaggcg atgacgctgc tgggcgagtg ccctcccggc cggccggccg aaccccggct
    30601 gtggctcacc aacttcaccg ccgaccgtct cgcccctgcc ctgcggctca cccggctgcc
    30661 gggcgtggtc gagcgggact gcgccgagat ctccgacggg gtcgggctgc gggacttcgc
    30721 ggggcgctcg ttccccggct ggcaccggca catcacgctg gcctgtgtcg cccatctggt
    30781 cagcgcggcg gcacgccggg gtgatgtcac ccacatcaac aggactaccg ttcggtaacc
    30841 tgacactctc ggccggttgg tgatgactca cctcccctga tgccccttac tctcgggccg
    30901 ggcctcactc tgggctcccg ttcgatcaca gcggatgtgc cacagcacgg gttggatcct
    30961 cagataggag attcatgctc agcctcgacc tgcgtccccc gaccgcagca cgagggacgc
    31021 tcaccacacc cttcccgtcc cgctcccacg acgaccgcct caccgagatc tcctcgatgc
    31081 tcttcgcctc gctgtcccgg agcgaccaat gcagaaaagg catgcagtac ttacggggcc
    31141 tgttggagac accgggtcgc aagtccatac gcaacatcgc ggcgctgctc ggcgagcagg
    31201 cgtcggagca gaacctccac cacttcatct cgggctccac ctgggactgg acgccccttc
    31261 gccgagcact cgccgagcac tggatcggtg aacgcccacc gcgggcgtgg gtggtgcagc
    31321 cggtcatcat ccccaagacc ggccggcatt ccgtcggcgt ggacaagcac ttcttcccga
    31381 ccctgggcca ggtgctcaac gcccagcgcg ccatcggcgt atgggccgcc tcggacacca
    31441 tcagcgcccc cgtcaactgg cgtctccatc tgccgcagac ctggctcaag gacgcgctgc
    31501 ggcgcagcca ggtgtcgatc ccggacggcg ttccggtgga gacgctgagc gagtccgtgg
    31561 tcgaggcgtg tctggaggcg gtgaaccgct ggcggctgcc ggtgcgtccg ttcgtcctcg
    31621 attcgtgcga ggtgcacgcc gtacccatct tcaccaggct gcacacggcc ggcatgccgc
    31681 tgctcgtcag cgtgtgcgag gaccagccgc tcacggtcgc ggatcccgcc ctgcccggcg
    31741 gcgggccggg gcagctgacg gccgagcaga tcatgctcat ggccagggac ctgcggcggc
    31801 cggtcatggc cgccgaccac aggcggggtg cgacgccgtt cacgcactgg gccgcgaccg
    31861 tacgggtcac cgggccgtcc ctgcccgcac cgtccgcggg acagggcgag gtgcggctgc
    31921 tgggggtcgg cgaggaggac gggcgttggc cggccaagct gtggctgacg aacctcaccg
    31981 aagtgccgcc ggcttcgctg gtgcggctga gcaagctggc cgaccgggtc gacctggact
    32041 tcacggagat caccgaccgg gtgggcatcc gggacttctc cgggcggtcc ttcgacggct
    32101 ggcaccgcca tgtgacgctg gcctcggccg cccacgccgt cgtcgcgctc gccaagggcg
    32161 cccagtgaac cgcgcctgaa cacccgcccg ccaggaccgg cgggcggacg gtcccgccga
    32221 ccgcccgccc gccggtccat cggcatgccc ggaggaaata cgggggtgcg tggcggaaca
    32281 cgggcttcga aaacactgcg ggaattcaac cggcgtaccg cggaggaaca acgcccgtgt
    32341 gtccggtccg acttgacata ttcgggacca cttgacggat cccgcctcac ctgacggagt
    32401 accgcgcacc ttgttggtga cgcgacgaat ccgttggacg atctagtgcg tcacggggat
    32461 ttcggccgtg cccttttccc gccatcccca tttccccctt cccttcccct tccccttctc
    32521 tttccccttc cccgcgcccc gcatcggcgt gcgcatcgtc gcgatcggag aaaccagtgg
    32581 acgacgctct gctcgatatt cgatatgaac aggcgttgca gcagcccccg tgggaggacg
    32641 aggcccaggt gctccgggtg cggaaggaac tcgccgcccg gctcccgctc gtcggcgccg
    32701 aggatgtgcg caccctgcgg tcgatgctgg cccaggtggc cgcgggcgac gcccatgtgg
    32761 tgcagacggg cgactgcgcg gaggacccgg cggagtcgac cgcaggccat gtcgcccgca
    32821 aggcgggcct gttgaacatg ctcgccggcc agctggagat ggacacgtcc cggcccgtgg
    32881 tgcgcgtcgg ccggatggcc ggccagttcg gcaagccgcg ctcgcgtccc accgagcggg
    32941 tcgacggcct cgaactcccc gtctaccggg gccacatggt caacagcccg gagcccgacc
    33001 ccgagctgcg ccgccccgat cccgggcggc tgctgtccgg ctacctggcc gcccgcgacg
    33061 tgatgggcca cctcggctgg ctcgacgctc ccggccctgc ccgcatcggc gcccccgtct
    33121 ggaccagcca cgaggccctg ctgctggact acgaggtgcc gatgctgcgt cggcagccgg
    33181 acggagagct gttgctcacc tccacgcact ggccgtggat cggcgagcgg acccggcagc
    33241 tcgacggcgc ccatgtcgcc ctgctcgccg atgtcgtcaa cccggtggcc tgcaaggtcg
    33301 gccccacgat gacgcccggc gaactgctgg cgctgtgcga acggctcgac ccgcggcggc
    33361 aggagggcag gctcaccctg atcgcccgga tgggcgccgg aaccgcggcc gagaggctgc
    33421 cgtcgctggt ggcggccgtg cgcgccgccg gccacccggt gatctggctg accgacccca
    33481 tgcacggcaa caccgtcagc acccccgacg gcctcaagtc ccgcttcctt cagacggtca
    33541 cgcgcgagat cgacgagttc cagcacgccg tcgccgcggc gggcggggtc gcgggcggac
    33601 tgcatctgga gaccaccccg gacgacgtca ccgagtgcgt ccgcgagctc tccgaggtcg
    33661 accgcgtcgg cacccggtac acgagcttct gcgacccgcg gctcaacccc gtacaggcgc
    33721 tctcggtggt ctcgtcctgg tggatgaccg gccggagcct ccagccgacc gccgcctagg
    33781 gatcggccgc gtcgccgcac cccacccgta tcccactcgc accccaccca caccccagcc
    33841 agcccttcgc ccgaggagag gacagtcatg gcgggcatac cccccatcga gccgtacccg
    33901 ctgccgtcgg cggacgacct gcccggcaac accgcagggt ggtccgccga tccggaccgc
    33961 gcggtgctgc tcgtccacga catgcagcgc tacttcctgc ggccgttccc cgcctcgctg
    34021 cgtgagccgc tggtgcgcaa cgccgccctg ctgcgcgagc gtgccgtcgc gacgggcatg
    34081 ccggtggcgt acaccgcgca gcccggcggg atgacggacg aacagcgcgg tctgctgaag
    34141 gacttctggg ggccgggcat gcgcgtcgac cccgtggacc gcgaggtggt cgagccgctc
    34201 acgcctgggc cggacgaccg ggtgttcacc aagtggcggt acagcgcctt cttccgctca
    34261 gggctgctgg agtggatgcg ggagcagggc cgcgaccagc tggtgctgtg cggtgtgtac
    34321 gcccatgtcg gggtgctgat gaccgcggtc gaggccttca cccaggacat ccgtacgttt
    34381 ctcgtcgccg acgcgatcgc cgacttctcc gccgagtacc accggcttgc cgtcgagtac
    34441 gccgcccagc gctgcgccgt cgtcagcacc accggcaccg tcctcgggca gctgggcacc
    34501 gccaccaccg ccggagccac cgtatgaacg cgcccgccga cctcctcgcc cgagtactgg
    34561 ccccgcaccc gccggccttc gccctgctgc accgcccgca gaccggcgga gcggacaccg
    34621 tggacgtcct gtcgggtggg atctccaccc cggccacgct cgcggacctg cccctgcccg
    34681 acggcgcggc gcccgccgac ggcccgcgtc atgagctgct gacgctgatc ccgtaccggc
    34741 agatcgccga acgcggcttc gccggccccg acgacggcga accgctgatc gcgatgaccg
    34801 tcgccgacca ggcccggctc ccgctggacg aggtcctgcg ccggctcccg gacgtgccga
    34861 tcgacatgac cggcggcgac ttcgacgtgg acgacgacac ctacgccgag accgtccgcc
    34921 gggtcatcac cgacgagatc ggcaccggcg agggcgcgaa cttcgtcatc aagcgctcgt
    34981 tcgtcgccga gatcagcgac tacggcacgc acagcgcgct gtcgttcttc cgccggctgc
    35041 tgcgcggcga gtcgggcgcc tactggacgt tcgtcgtcca caccggcgag cggaccttcg
    35101 tcggggcgac gcccgagcgg cacctgagcc tcctggacgg caccgccgtg atgaacccca
    35161 tcagcggcac ctaccgctat ccgccgggcg gtccgacgct gcccggggtg ctggacttcc
    35221 tcgccgaccg caaggaagcc gacgagctgt acatggtcgt cgacgaagag ctgaagatga
    35281 tggcccggat ctgcgacacc ggtggccggg tcgtgggccc gtatctcaag gagatggccc
    35341 ggctcgcgca caccgagtac ttcatcgagg gccgcagcac ccgcgaccct cgggacatcc
    35401 tgcgcgagtc gctgttcgcc cccacggtca ccggcagccc gctggagagc gcctgccggg
    35461 tcatcagccg gtacgagccc gagggccgcg gctactacag cggtgtggcg gcgctcatcg
    35521 gccgcgacgc gggcggcggc cgcgcgctgg actcgtccat cctcatccgc accgccgaca
    35581 tcggcccctc gggccgggtg cggatcggcg tgggcgccac gctcgtgcgc cactccgatc
    35641 cggactccga ggtcgccgag acccgcgcga aggcggcggg gctggtcgcc gcgctccagg
    35701 cggaccggcc agccgccggg caggcgtcgg cgggtgccgt gctcctcggc gaccatccgg
    35761 acgtgcgtgc ctcgctggag cggcgcaaca ccacgctcgc gggcttctgg ctcgcggggg
    35821 acggcggacg ggaacgcccg ctgccggacc tggcgggcag ccgggtgctg gtggtggacg
    35881 ccgaggacac cttcacctcg atgatcgacc accaactgcg gtccatgggc ctagatgtga
    35941 cggtccgtcg cttcgacgac ctgtacggct tcgacggtca tgacctggtc gtcatgggcc
    36001 ccggcccggg tgatccgcgt gagaccggcc accccaagat cgcccatctg cggtccgcga
    36061 tcgacacgct gctcaccgag cggcggccct tcctcgccgt ctgcctcagc catcaggtgc
    36121 tcagcatgcg cctcggcctg cccctgacgc gccgggaggt gccgaaccag ggcgtgcagc
    36181 aggagatcgc cttcttcggc gcccgtgaac gggtcggctt ctataacacg ttcgccgccc
    36241 gcagcgccga ggacaaggtc gaggtcgagg gcgtgggcct ggtggaggtc agccgcgacg
    36301 cggagaccgg tgaggtgcac gcgctgcgcg gtccgcactt cgcctcgatg cagttccacg
    36361 ccgagtcggt gctcaccgag gacggtgtgc gcctcttcgg cgccctgatg acggacgtcc
    36421 tgggcgtccg gctctgacca caccccggcg gcgggcgctc gccgggcacg acggcgtgct
    36481 cgcgccgggc ggcggcgccg tcctcgacgc gggcacccgc gcgctgctcg ccggccggcc
    36541 cgtggtctgg cggtcgatgg gcgccgacgc ggccgcccga cgcgccgggc tcgacctggc
    36601 ccgcccgctg ctcgcggccg aaccgcaccc ccggtggtgg gagttggcgg aggcacggcg
    36661 gcacctctac gccgaggccg cgtcggcgag ggtcgccacg gacggccgta cgcccgacga
    36721 ggtcgccgaa gcggtcctgg acgtactgga gttgacgacg aggcccaggt gacatcgcga
    36781 tggccggttc tcaaccccct tggcactgtg cggacttgtc gcgcccagag gcatgtgatt
    36841 aacctgatgt cagttgtcag acaactgagg ggaccgtccc atggctctgc gtccgatcgc
    36901 ccggccctcc acggcgcgcg aggtcatcgc gctgctccac cgggagctcg ccgacggagc
    36961 ctggcccatc ggctccagga tcccctccga gacggagctg gccgcgcagc tgggcgtgag
    37021 caggcccacc atccgtgagg ccgtcagcgc gctggtgcac accggcatgc tggaggcgca
    37081 gcgcggcaag ggggtcttcg tgcggtcggt gtccgacccg gcgcccatgc tgcagagcat
    37141 cgaactcgcc gatgtgcgcg atgtgttcga ggtacagctc tgcttcgacg tgcaggcggc
    37201 gcactccgcg gccctgcgcc ggacgcccga ggacatggcg cggctgcggg agttgctccg
    37261 ggcgcgggcc gaggcggccg gccgggacga cgccgagttc ggcaagcggg acgccgcgct
    37321 gcatctggcc gtcgtcgagg cggcccgcaa tgtgacgctc accgagtgct accgcttctt
    37381 cgtggggcgg ctccaggaga gcctggacct gttcgccggc gcggacaccc acctggagtg
    37441 cggcgtcgaa gcccatgaag cactcgtccg ggccatcgag gagcaggacc ccgaggcggc
    37501 cgcggcggcg gcccggcatg tcgtccgcac cagtctcgac gccctggagg ggctgctggc
    37561 ggtgcgcgcc gccgagccga agggcggctg accgctcctg ccatgacggc gggcacagct
    37621 gaggcggcgc gacagggagg gaacacccca tgccgacacc cggggaccgg cgtctcgtcg
    37681 ggcgcgagcg ggaacaggcg gcgttacggg ccgcgctgga cgcgacggcg gcgggcaggg
    37741 gctccctgct gctgttccac ggaccgtccg ggtccggcaa gtccctgctg ctgcggacgg
    37801 ccggtgcgcg ggcggcgctg cggggcatgg ccgtgtcgac cgcccgactg gcccggctcg
    37861 accagcactc cgcgatggcc ccgctgctcg cggcgctcag caccggcccg catccggtgc
    37921 tcagtgccgt gcaggcgggc tcgctggccg agttcgccga ccggcccacg cactggagcc
    37981 ggctgatcga gcggctgcac cgcctcatcg agcggcgggc cgcacactcc cccctggtga
    38041 tcgtcctgga cgacctccag tgggcggacg agctgaccct ggccgccttg gagaccctgc
    38101 tcccccggct cgccgacgta ccggtcctgt ggctggccgc ctacaccgac ttccccgtcg
    38161 tacggcccac ccgggacgcc ctcgaccggc tgccggccgc ccatgccgag gtcgtgccgc
    38221 tgtccgcgct ggacgggccg gccgccgccg agctggcggc ccaactcctc ggcacggtag
    38281 ggcccgagga catccgccgg gtggtgaccg cgacgggcgg catccccgcc ctcatcgagc
    38341 gcctggtcca actgctgcgt gaggaggggc ggatccgcac ggaggacggc acggtgcgtg
    38401 tgctgggcgg gcatccaccc gccgatctgg cccgggcggc ggccccggta ctgtccggac
    38461 tcgcccagca gacccgcgaa ctgctgcagg tgggcgcggt gctggggccg cgcttctcac
    38521 tgcgggaggt gtccgcgctc accggccggt cgacgatgga gctggccacc gcggcccagg
    38581 aggcggcggc cgccgggctg ctggaggacg acggcgccgc gttccgtttc cgggccccgc
    38641 tcgtccacca ggccctccac gacagcctcc tcggccccgt gcgccgcgcg ctgcacgcgg
    38701 aggcggcccg gctgtgcgcg gcggaggggc ggccctgccc ggagaccatc gggcatctga
    38761 tcctctccgg caccgaggag gacctggagc agggcgccgc ccacctggaa tggctgaagc
    38821 gcaacgagga ctccgtaccg tcccacgagc gtgaggaact gtcccgggcg ctgctcaccc
    38881 aattacgccg gtacgacccg ctcgcgaccg ggcccgtgcg gacggcggta cgtctcttcc
    38941 tcgccaccgg tcagcccggc accgcccacc ggatgctcga cgcggccctg gccggcgcgg
    39001 gctgggagac ggacgccgag gccgaggcgt tcgccgaact cgtggaagtg ctgctgcggt
    39061 cggggcaggc ccatgacgcg ctgcggcatc tgcggcgggc ggccgaggac acccgttccc
    39121 ccgcccgccg ccaggcgtgg ctcaccgcgc tggaggcacg ctgcctggcc gccgccggga
    39181 acgaccccgc gcacgccgca cggctggccc ggtccgcggt ggtgctggcc cggcagaccg
    39241 cggaccacgc ctcggcggcc ctcggcacgg ccctgctcgc cgggttcgcg cagcgcgcgg
    39301 gcgacatcgg cacggcatcg cggctggccg gcgaggcggt cgcgggcgga ccgtacggcg
    39361 cggagcggag cttcggctgg ggactggccg tgcccgcgct ggtcctcagc tcggccgggc
    39421 gcccgctgga cgcgggcgag gtgctgaagg cgtggcggaa cgcgaccggt gagcaggcct
    39481 gggggtgggc ggcgccgcgc tggcatctcg cccggtccgt gcagctgtgg cactgcggcc
    39541 ggctcgccga cgccgagcag gaggcgcagg ccggtctgga ggcctgcggg cggctcgacg
    39601 accccggcag ccgcaaggca ctgcgggcca tgctgacgct gctggcgacc gtgcgcggag
    39661 acctggagcg ggccgccgcg cggtcggcct cgccggaagg cccgccgtcc gggtccgtcg
    39721 gtgccttccc ggcactggtc ggcgcgctcc ttctcgacgc gtcgggcgac ccggaggcgg
    39781 ccgtgcggca gttggcgggg ctgtgggccg atccggagcg gcacacctgg ctgctggccg
    39841 cggatccgct ggtcctgccg cacctggtcc ggatcgcgct gcgggccggc gcccacgagc
    39901 aggccgccga ggcggtcgac ctggcccgcc ggctggcccg gcagagcccc ggcatcaccc
    39961 cggtgaccgg agccgcgctg cactcccagg ggctgtaccg cggtctcgcg gctcccctgc
    40021 accgtgccgt acgggtcttc cgcggcggat cgcatccgct ggccctggcc tccgcgctgg
    40081 aggacgcggc ggacgccacc cgggcgcagg gcgagccgct gcgcgcgacc gagatgctgc
    40141 aggaggccca gcgcatctat gtggccgccg gagcggggct cggcgcggag cgggtgcggc
    40201 gccggacccg gttctcaccc ggccggaccg tcggggaact gccggccgcc cggcgggccc
    40261 cggccgtgcc ctcggcgcga gcggcggagg gcacggccga ctgggacagc ctcaccccgt
    40321 ccgaggtgcg tgtcgtacgg ctggtcgcgg agggtctgac gaaccgggag accgcccagc
    40381 ggctcgcggt ctccgcgcac accgtggact cccatctgcg ccgcgccttc gccaagctgg
    40441 gcgtgtcgcg acgggtggag ctggcccgcc atgtgctggc gcacacctcg aagtagcccc
    40501 acccgaccga cagggagacg agcacccatg cgcgctgctg acgccgcctc ggcgacgacc
    40561 cggaccgaga cggaggtgtc gggcggccct ctggtcggcc ggctggaggg gccgggcggg
    40621 ctggtggcgg cgtaccgcgg tgtgccgtac gcggcaccgc ccgtcggccc ggaccggttc
    40681 gcgccgcccc ggccacatcc cggctggagc gagccgctgc gggcggacgg cgcggtgggc
    40741 accgtgccgt tgcaactgcc gtcccccttc gccgcgttgc tcggcgaccc tctcgacccg
    40801 ccgcacacgg aggcctgtct gacggtgaac gtgtgggcgc ccgtcggccc cggcgacggt
    40861 ccccgcccgg tgctggtgtg gctgccgggc ggcagcttcc tgaccggcgg cgccgacctg
    40921 ccccggtacg acggtgccga actggccgct cgggagggga tcgtcgtcgt cctggtcaac
    40981 taccggctgg gcgcgctggg tttcctcgcc ccgtcctggg cggagccggc cgccgtcgag
    41041 ggcgtgggca cctcgctgtc gttccggatg ccgcaggggg cgacccatgt cacgaacgcg
    41101 gggctcctcg accagatcgc cgcgctgcgc tgggtgggac gcgagatcca cgccttcggc
    41161 ggggaccccg accgggtcac ggtggtcggc cagtcggcgg gcgggcagtc cctggcggcc
    41221 ctgctggcgc tggagcaggt gcgtccgctg ttccggcgcg cggtcctgca cagcgcgccg
    41281 ctgggcatgg cgccgcagac ccggcaggag gcggccctgg tcgccgacga cttcctcgcg
    41341 gcgctcgggg cggacgccgg gcggttgcgg acggtgcccg gcgagcgcgt gctgctcgcc
    41401 cagcggcagg tcctcgcccg gccccgccga cgcggggacg tacggccgcc gttccagctg
    41461 gtcgccgacg acgcggtcgt cgccgccgat ctgccgggcg ccctgcgcac ggcacccccg
    41521 ccggacgggc tcgacctcct cgcgggcgtc acccggcacg agtgcgccct gtggttcggc
    41581 gaggacccgg gcctggacgg cctgacgcgc gaggaggtgg cggcggagtt cagcgcggtg
    41641 ttcggccccc gagcccagga agccctctcg cactacaccc ccggcaccga gtggcgcgtc
    41701 gccttcgagg agttgaagac cgacgcgttc ttcaccgcgc ccacccagga gttcgccgac
    41761 ctcgccgact cgtggggcgc gaccgtccgg ctgttccgct tcgactggcg ggtacccggc
    41821 cgacacgcgc gtctacgggc ctgccactgc gcggagatcc cgttcctcct gggccgcacc
    41881 gaggcccgac acgccccgct cttcgccgac gccgaccagg aggagatggc cgcgctgcgg
    41941 gggcggatgc ggcgtctgtg gggcgagttc gtacggaccg ggacgatgac cgaccactgg
    42001 ccgccgcacc gccgcgagca gcccgcggtg cgggtcgtcg gcggcgagcg ggacggtgag
    42061 gtcctggggg cgctgctgga gtcgggacga cggcggttgt gggagtgacg tacgaaggtg
    42121 ccgccggaag gatcccagcg gcaccgcggt ggggcgggtt ggtacggacc ggcacgacag
    42181 ccgacaactg gcccccgcac caccgcgagc agcccgcggt gcgggtcgtc ggcggcgagc
    42241 gggacggtga ggtcctgggg gcgctgctgg agccggggcg tgggcggatg tgggagtgac
    42301 gtacacggag gtaccgctgg aaggatccgg gcggcaccac ggtggggcga gtgccgtcag
    42361 agccgcgggg gtggcgtcgg tggcgtgcgt tcatatggac cgggcgctcc gccggccgcc
    42421 gcaccgccgt acacgaaggt gccgccggaa ggatccggcg gcacctcggg tgggtggtgt
    42481 cagatggtca gcagggtgcg gtccaggtcg ctctgggcgt tgaagatgga gcgctcgggg
    42541 tcggtgatgg cgcggcggcc gtgcatcacc cgggtgttgt cgatgagcgc cacatcgccg
    42601 tcggcccagg cgagttcctc ggtcaggtcc tcggtgacgc tctccacctc cttgaggatg
    42661 cgcacgggta tgtcccggcc gtcggcgaag gtgatgcgcg gcttctcgta gtggttggag
    42721 gggccgagga tgctgttggc gaaggcgagg cgctcgtcga agagggtgcc gtgcgccgcg
    42781 gagacccggt aggcgtagtg gatcgagccg tcgccgagca ggtcgatgac ggtctcgccg
    42841 gggcccccgg ccagctcgcg caactggtcg acggtgaccg aggcggcgtc ggaggtgccg
    42901 aggtggaagg cggcgaaggc cttccacttg gtctcctcga cccgtcggct gtagacgatc
    42961 tcgtgggccc ggaagagacc gcgggcctcc tcgctgagcg cgtcccacac ccggtggccg
    43021 tcgcacacgg tggtctggga gccggacgag gcggccttct cgcagtagaa ccaggtgagg
    43081 gtcggcgcga acgggctgtt gccgttctcc aggtgcaggc cgaccgcttc atgaccggcg
    43141 tccaccttct gcgcggtgga gccgccgtgg aaggagcggg ccgggtcgag ggtgacgcgc
    43201 tcggagtggg cgccgacgaa cgccgagaac tgttcgaggt ccgggcggaa gccgcgcagc
    43261 agcaggaacc ccgcctcgcg gagcgtccgg atcacctggc cgggcgccag ggtgcccagg
    43321 gtcgttccgg gctcggccgg cgtcaggagc aggccggtgc cggagccgta ggaggtcaca
    43381 cgcgcatggt cgatcatggt ttctcctcgg agtatggatg cggtcgatac agccgatacg
    43441 ggggagctgc cagatgtgcc cgcgaggtga gggcggtcac ccgaagcggc cggccgtgac
    43501 ggcctcgtgg accgcggagc gccgggggcg tccggtgacg gtgaagaact cg
//
