LOCUS       NZ_BNBM01000001        26706 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces lanatus strain JCM 4588 sequence01, whole genome
            shotgun sequence.
ACCESSION   NZ_BNBM01000001
VERSION     NZ_BNBM01000001.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces lanatus
  ORGANISM  Streptomyces lanatus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 1203604)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 61X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014655715.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 05:46:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,254
            CDSs (total)                      :: 9,172
            Genes (coding)                    :: 8,973
            CDSs (with protein)               :: 8,973
            Genes (RNA)                       :: 82
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 199
            CDSs (without protein)            :: 199
            Pseudo Genes (ambiguous residues) :: 0 of 199
            Pseudo Genes (frameshifted)       :: 83 of 199
            Pseudo Genes (incomplete)         :: 153 of 199
            Pseudo Genes (internal stop)      :: 16 of 199
            Pseudo Genes (multiple problems)  :: 50 of 199
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:57:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 73180
            Orig. end                         :: 99886
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BNBM01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26706
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26706
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26706
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16706](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16706)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(433..446)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.67"
                     /tool="antismash"
     gene            2202..2999
                     /locus_tag="IE325_RS00355"
                     /old_locus_tag="GCM10018780_00700"
     CDS             2202..2999
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069689.1"
                     /locus_tag="IE325_RS00355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_00700"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_190067577.1"
                     /transl_table=11
                     /translation="MTQQIPSTEPELAGVRNFRDVGGLPTVDGRRVRHGVLFRSGHLAH
                     ATAEDAAFLDSLGLHTVFDFRNAADQKLEGPDVELPGVRNVNLPLSDPADGAEFWKMVR
                     DGDLDQLRAILADGKGANRMIVSYRSIIKERTGEHSQVLHSLAEDSVPALMHCAAGKDR
                     AGLSIAVTLLALGVEREAIVTDYLESNAKHRRYKVRRSGSGASAYSPEVMELLSPLFDA
                     RAEYLTAAFETIEETWGGVDTYLEQGLRLSPESRELLRERLLD"
     gene            complement(3016..3135)
                     /locus_tag="IE325_RS00360"
                     /old_locus_tag="GCM10018780_00710"
     CDS             complement(3016..3135)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018566809.1"
                     /locus_tag="IE325_RS00360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_00710"
                     /product="DUF6126 family protein"
                     /protein_id="WP_190067578.1"
                     /transl_table=11
                     /translation="MSNTEDRFPRALWIRLIIYIAVGHLFAAFIYFLFEAGAK"
     gene            complement(3132..3755)
                     /locus_tag="IE325_RS00365"
                     /old_locus_tag="GCM10018780_00720"
     CDS             complement(3132..3755)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009191626.1"
                     /locus_tag="IE325_RS00365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_00720"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_190067579.1"
                     /transl_table=11
                     /translation="MSSSETEPSAEHEVALPVVAPQLRALRRRAALTLEAAARAAGLSP
                     AHLSRLETGQRQPSLPMLLALARIYGTTVSELLGETVAERDAVVRAGDMEPTAAGGWTY
                     WQAGAHGRGMQALRVHVPHGSQGDIVRVHAGEEWLYVLQGRLRLRLGDTTHRLAPGDSA
                     HFDSLTPHRIAAQDEGGVELLFVHTLLQSPTATLCLGPTPGVTP"
     misc_feature    complement(3761..3781)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 22.29"
                     /tool="antismash"
     misc_feature    3816..3834
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 24.67"
                     /tool="antismash"
     gene            complement(3832..5217)
                     /locus_tag="IE325_RS00370"
                     /old_locus_tag="GCM10018780_00730"
     CDS             complement(3832..5217)
                     /NRPS_PKS="Domain: Aminotran_3 (41-363). E-value: 6.4e-90.
                     Score: 293.5. Matches aSDomain:
                     nrpspksdomains_IE325_RS00370_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494124.1"
                     /locus_tag="IE325_RS00370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_00730"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_190067580.1"
                     /sec_met_domain="Aminotran_3 (E-value: 6e-88, bitscore:
                     291.2, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSEFDLGALLAERGAERYELHSKYLNHQLPRMLHTIGFDKVYER
                     AEGAYFWDADGDDYLDMLAGFGVMGLGRHHPVVRKALHDVLDAQLADLTRFDCQPLPGL
                     LAERLLAHSPHLDRVFFGNSGTEAVETALKFARFVTGRPRVLYCDHAFHGLTTGSLSVN
                     GESGFRDGFAPLLPDTAVPLGDLDALARELKKGDVAALIVEPVQGKGVHETPPGYLRAA
                     QELLRKHKALLIADEVQTGLGRTGDFYAYQHEEGVEPDLVCVAKALSGGYVPVGATLGK
                     DWIFKKVYSSMDRVLVHSASFGSNAQAMAAGLAVLSVMENEQTVANARATGEQLRSRLA
                     ALIDKYELLADVRGRGLMIGIEFGRPKSLGLRSRWSMLQAARKGLFAQMVVVPLLQRHR
                     ILTQVSGDHLEVIKLIPPLVIGEREVDRFVDAFTDVMDDAHSGGGLMWDFGKTLVKQAV
                     ANR"
     aSDomain        complement(4129..5094)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS00370_Aminotran_3.1"
                     /evalue="6.40E-90"
                     /label="IE325_RS00370_Aminotran_3.1"
                     /locus_tag="IE325_RS00370"
                     /protein_end="363"
                     /protein_start="41"
                     /score="293.5"
                     /tool="antismash"
                     /translation="VYERAEGAYFWDADGDDYLDMLAGFGVMGLGRHHPVVRKALHDVL
                     DAQLADLTRFDCQPLPGLLAERLLAHSPHLDRVFFGNSGTEAVETALKFARFVTGRPRV
                     LYCDHAFHGLTTGSLSVNGESGFRDGFAPLLPDTAVPLGDLDALARELKKGDVAALIVE
                     PVQGKGVHETPPGYLRAAQELLRKHKALLIADEVQTGLGRTGDFYAYQHEEGVEPDLVC
                     VAKALSGGYVPVGATLGKDWIFKKVYSSMDRVLVHSASFGSNAQAMAAGLAVLSVMENE
                     QTVANARATGEQLRSRLAALIDKYELLADVRGRGLMIGIEF"
     gene            complement(5214..7142)
                     /gene="dxs"
                     /locus_tag="IE325_RS00375"
                     /old_locus_tag="GCM10018780_00740"
     CDS             complement(5214..7142)
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386171.1"
                     /locus_tag="IE325_RS00375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_00740"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_190067581.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 3.8e-112,
                     bitscore: 369.9, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.2e-06, bitscore:
                     24.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTILESIRGPRDLKALSETDLRELSEEIREFLVHAVARTGGHLGP
                     NLGVVELSIALHRVFESPVDRIVWDTGHQSYVHKLLTGRQDFSKLRGKGGLSGYPSREE
                     SEHDIVENSHASTALGWADGLAKARQVQGEKGHVVAVIGDGALTGGMAWEALNNIAAAK
                     DRPLIIVVNDNERSYAPTIGGLANHLATLRTTDSYEKVLAWGKDVLLRTPIVGGTIYES
                     LHGAKKGFKDAFAPQGMFEDLGLKYVGPIDGHDIGAVESALRRAKRFHGPVLIHCLTEK
                     GRGYEPALAHEEDHFHTVGVMDPLTCEPLAPSGGPSWTSVFGEEIVRIGEEREDVVAIT
                     AAMLHPVGLGKFAERFPDRVWDVGIAEQHAAVSAAGLATGGLHPVVAIYATFLNRAFDQ
                     LLMDVALHRCGVTFVLDRAGVTGADGASHNGMWDMSILQVVPGLRIAAPRDADQLRAQL
                     REAVACDDAPTLVRFPKESVGPSIPAVDRVGGLDVLHRDAGEPDVLLVAVGVMAPVCLQ
                     AAELLQARGINCTVVDPRWVKPVDPALAPLAAQHRLVAVVEDNSRSSGVGSAVALALGD
                     ADVDVPVRRFGIPEQFLAHAKRGEVLADIGLTPVEVAGRISASLALKEADGGQVRRIVA
                     PVKEKAE"
     gene            complement(7170..8327)
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="IE325_RS00380"
                     /old_locus_tag="GCM10018780_00750"
     CDS             complement(7170..8327)
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031167.1"
                     /locus_tag="IE325_RS00380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_00750"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_190067582.1"
                     /transl_table=11
                     /translation="MTAISLGVPEVPVRPVAERRVSRQIQVGPVAVGGGAPVSVQSMTT
                     TRTSDIGATLQQIAELTASGCQIVRVACPTQDDADALATIARKSQIPVIADIHFQPKYV
                     FAAIEAGCAAVRVNPGNIKQFDDKVKEIARAAKDHGTPIRIGVNAGSLDRRLLQKYGKA
                     TPEALVESALWEASLFEEHDFRDIKISVKHNDPVIMIEAYKQLAAQCDYPLHLGVTEAG
                     PAFQGTIKSAVAFGALLSQGVGDTIRVSLSAPPAEEVKVGIQILESLNLRQRRLEIVSC
                     PSCGRAQVDVYKLADEVTTGLEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQI
                     FVKGEVIKTVPESKIVETLIEEAMKIAEQMEQDGVASGEPAVTVS"
     gene            complement(8332..9354)
                     /gene="hpnH"
                     /locus_tag="IE325_RS00385"
                     /old_locus_tag="GCM10018780_00760"
     CDS             complement(8332..9354)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386169.1"
                     /locus_tag="IE325_RS00385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_00760"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_030945596.1"
                     /sec_met_domain="PF04055 (E-value: 1.7e-18, bitscore: 63.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 1e-09, bitscore: 34.2,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQSIKVATYLAEQKLRRRDKFPLIVELEPLFACNLKCEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVAKRKYVF
                     LCTNAMLLRKKMDKFTPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVEAIKEAKRRGF
                     RVTTNSTFFNTDTPQTIVEVLNFLNDDLKVDEMMISPAYAYEKAPDQEHFLGVEQTREL
                     FKKAFAGGNRRKWRLNHSPLFLDFLEGKVDFPCTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRELIEDTDWDKYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESLRAMRETVSGNRE
                     "
     gene            complement(9360..10001)
                     /locus_tag="IE325_RS00390"
                     /old_locus_tag="GCM10018780_00770"
     CDS             complement(9360..10001)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431357.1"
                     /locus_tag="IE325_RS00390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_00770"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_190067583.1"
                     /transl_table=11
                     /translation="MSPQPAPAPLLIACALGIEQFALRAGERGGAGGPVTVLRTGMGPR
                     AAERSVTRVLADPALSGAAVLATGFCAGLAPGMHPGDLVVAEETRDPAGTVPCVGTDLL
                     VKELVRTIPGRTVHTGPLTGSDHVVRGQERSDLLATGAIAVDMESAVTLLSAVRTGERP
                     VAAVRVVVDAPEHELVRIGTLRGGISAFRVLRSVLPAFYEWHRSLLLPRR"
     gene            complement(10001..12016)
                     /gene="shc"
                     /locus_tag="IE325_RS00395"
                     /old_locus_tag="GCM10018780_00780"
     CDS             complement(10001..12016)
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019985322.1"
                     /locus_tag="IE325_RS00395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_00780"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_190067584.1"
                     /sec_met_domain="T2TS (E-value: 1.6e-150, bitscore: 498.2,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSTGAPAPRAAAASDTDSETPVAAGVHEVAEHAVRRATD
                     FLLAKQDAQGWWKGDLETNVTMDAEDLLLRQFLGIRDEKTTRAAALFIRGEQREDGTWG
                     TFYGAPGELSATIEAYVALRLAGDAPDAPHMARASAWIREQGGIAASRVFTRIWLALFG
                     WWKWEDLPELPPELIYFPKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELH
                     TDPADPNPLKPLAPVASWDGAFQRLDKALHQLRKVAPRRLRRAAMNSAARWIIERQEND
                     GCWGGIQPPAVYSIIALRLLGYDLEHPVMREGLASLDRFAVWREDGARMIEACQSPVWD
                     TCLATIALVDAGVPADHPQLVKAADWMLGEEIVRPGDWAVKRPELPPGGWAFEFHNDNY
                     PDIDDTAEVVLALRRVRHHDPERVEKAIGRGVRWNLGMQSRNGAWGAFDVDNTSPFPNR
                     LPFCDFGEVIDPPSADVTAHVVEMLAVEGLAHDPRTRRGIRWLLAEQEPDGSWFGRWGV
                     NYVYGTGSVVPALVAAGIPGSHPAIRRAVTWLESVQNDDGGWGEDLRSYKYVKEWSGKG
                     ASTASQTAWALMALLAAGERDSKAAERGIEWLAATQREDGSWDEPYFTGTGFPWDFSIN
                     YHLYRQVFPLTALGRYVHGEPFADKAGAALAEAKGS"
     misc_feature    12125..12140
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.62"
                     /tool="antismash"
     misc_feature    complement(12128..12143)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.27"
                     /tool="antismash"
     gene            complement(12160..13224)
                     /locus_tag="IE325_RS00400"
                     /old_locus_tag="GCM10018780_00790"
     CDS             complement(12160..13224)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972234.1"
                     /locus_tag="IE325_RS00400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_00790"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_190068463.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 6.1e-58, bitscore:
                     192.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPASKAARETAVDVTALLERGRTLTTPVLRAAVDRLAPPMDTVS
                     AYHFGWIDADGNPTAGDGGKAVRPALAVLSAEITGAAPEVGIPGAVAVELVHNFSLLHD
                     DLMDGDEQRRHRDTVWKVHGPAQAILVGDAMFALANEVLLELGTVEAGRATRRLTTATR
                     ALIDGQAQDISFEHRDRVGVEECLEMEGNKTGALLACASSIGAVLGGADDRTADTLEKY
                     GYHLGLAFQAIDDLLGIWGDPEATGKQTWSDLRQRKKSLPVVAALAAGGPASERLGEIL
                     AADAKSSDFENFSEEEFAARAALIEEAGGREWTAAEARRQHTIAVEALDAVDMPEQVRA
                     RFTALADFVVVRKR"
     gene            complement(13296..14723)
                     /gene="hpnE"
                     /locus_tag="IE325_RS00405"
                     /old_locus_tag="GCM10018780_00800"
     CDS             complement(13296..14723)
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494137.1"
                     /locus_tag="IE325_RS00405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_00800"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_190067585.1"
                     /transl_table=11
                     /translation="MTEGTRPEGSLADIPGHSGRDAVVIGGGLAGITSALALADAGVRV
                     TLIEGRPRLGGLAFSFQRGDLTVDNGQHVYLRCCTAYRWFLDRIEGTALAPLQDRLDVP
                     VLDLDKPEGRRLGRLRRDALPVPLHLGRSLATYPHLSLAERAKVGRAALALKGLDLADP
                     TLDTQDFGSWLTAHGQSARAVEALWDLVGVATLNAVAGDASLGLAAMVFKTGLLSDPGA
                     ADIGWAHVPLGELHDRLARKALDTAGVRTEVRTRVTSISSDENGRWSVEVPGETLHADA
                     VVLAVAQREAYDLLPDGALDAPEKLLEIGTAPILNVHVVYDRKVLSTPFLTALGTPVQW
                     VFDRTEASGLRDGQYLALSQSAAQDEIDEPVAALRERYLPELERLLPGARGAHVKDFFV
                     TRERTATFAPTPGVGRLRPGARTKASGLYLAGAWTATGWPATMESAVRSGVSAAGAALS
                     ALGRPRPSHLFSVEEAA"
     gene            complement(14720..14863)
                     /locus_tag="IE325_RS46935"
     CDS             complement(14720..14863)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) triceptide_precursor"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF039420.4"
                     /locus_tag="IE325_RS46935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6380 family protein"
                     /protein_id="WP_350895672.1"
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDIPAQGDATGEKRQATLRSHAASLTETTGRGPLNHRRGGRAGEG
                     AR"
     gene            complement(14863..15810)
                     /gene="hpnD"
                     /locus_tag="IE325_RS00410"
                     /old_locus_tag="GCM10018780_00810"
     CDS             complement(14863..15810)
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994383.1"
                     /locus_tag="IE325_RS00410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_00810"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_190067586.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.4e-55, bitscore:
                     184.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2e-68,
                     bitscore: 226.8, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTVESAPHASAPVLAAYSYCEAVTGQQARNFAYGIRLLPTSKR
                     RAMSALYAFSRRVDDIGDGALTGDVKVARLEDTRQLLTRIRDREVDEDDVDPVAVALAH
                     AADVFPIPLGGLDELIDGVLMDVRGETYETWDDLKAYCRCVAGAIGRLSLGVFGTEPGA
                     RGAERAPEYADTLGLALQLTNILRDVREDAEGGRTYLPSDDLAKFGCSAGFSGPTPPEG
                     SDFAGLVHFEVRRARALFAEGYRLLPMLDRRSGACVAAMAGIYRRLLDRIERDPEAVLR
                     GRVSLPGREKAYVAVRGLSGLDARHVTRTVRRRA"
     gene            complement(15807..16706)
                     /gene="hpnC"
                     /locus_tag="IE325_RS00415"
                     /old_locus_tag="GCM10018780_00820"
     CDS             complement(15807..16706)
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996262.1"
                     /locus_tag="IE325_RS00415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_00820"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_190067587.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.4e-37, bitscore:
                     125.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.5e-40,
                     bitscore: 135.3, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRTGAPSDDPERGTLDKAAAENFPVAPFFLPRAWRTDLMAVYGF
                     ARLVDDIGDGDLAPGGADARLLGVPPEDAEDRLILLDAFEADLRRVFDGTPSHPLLRRL
                     QPTVRRRSLTPEPFLGLIAANRQDQLVGRYETYDDLLAYCELSANPVGRLVLAVTGTET
                     PERIRLSDAVCTALQIVEHLQDVAEDLGRDRIYLPAADMKRFHVQETDLAAETAGASVR
                     ALVAYEAERARLLLNEGTPLVGSVHGRLKLLLAGFVAGGRAAIRAIAAAEYDVLPGPPK
                     ASKRQLLREVGVTLRGEG"
     gene            complement(17097..17876)
                     /locus_tag="IE325_RS00420"
                     /old_locus_tag="GCM10018780_00830"
     CDS             complement(17097..17876)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330378.1"
                     /locus_tag="IE325_RS00420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_00830"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_190067588.1"
                     /transl_table=11
                     /translation="MAEQRADAHIPTVIADELHIVYRVNGAKSGKGSATAALSRIMKRG
                     EERGVRKVHAVRGVSFVAYRGEAIGLIGSNGSGKSTLLRAIAGLLPPEKGKVFTDGQPS
                     LLGVNAALMNDLTGERNVILGGLAMGMTREQIKERYQGIVDFSGINEKGDFITLPMRTY
                     SSGMAARLRFSIAAAKDHDVLMIDEALATGDRKFQKRSEDRIRELRKEAGTVFLVSHNN
                     KSIRDTCNRVLWLERGELRMDGPTDEVLKEYEKFTGK"
     gene            complement(17869..18798)
                     /locus_tag="IE325_RS00425"
                     /old_locus_tag="GCM10018780_00840"
     CDS             complement(17869..18798)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964854.1"
                     /locus_tag="IE325_RS00425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_00840"
                     /product="ABC transporter permease"
                     /protein_id="WP_190067589.1"
                     /transl_table=11
                     /translation="MSETTHDGSVAVSAPPSPDEGLTAAQLAAKYGLAVSGARPSLFEY
                     VRQLWDRRHFILAFSRAKLTAQYSQAKLGQLWQVATPLLNAAVYFFIFGVILQADRGMP
                     REVYIPFLVTGVFVFTFTQSSVMAGVRAISGNLGLVRALHFPRASLPISFALQQLQQLL
                     YSMIVLFVVAIGFGSYPKLSWVLILPVLVLQFLFNTGLALIMARAGAKTPDLAQLMPFV
                     MRTWMYASGVMFSIPIMLKGKPDWIATVLQWNPAAVYMDLMRFALIDGYDHTQLPDHVW
                     AAAAGWAVLFAVGGFVYFWKAEERYGRG"
     gene            complement(18892..19737)
                     /locus_tag="IE325_RS00430"
                     /old_locus_tag="GCM10018780_00850"
     CDS             complement(18892..19737)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018568725.1"
                     /locus_tag="IE325_RS00430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_00850"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_190068464.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 4.1e-12,
                     bitscore: 42.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGNRPDELRALLDSVAKQDGDKVEVVVVGNGSPVPDVPEGVRTIE
                     LPENLGIPGGRNVGIEAFGPSGRDVDILLFLDDDGLLAHHDTAELCREAFTADPKLGIV
                     SFRIADPDTGVTQRRHVPRLRAADPMRSSRVTTFLGGANAVRTQVFAEVGGLPDEFFYA
                     HEETDLAWRALDAGWMIDYRSDMVLFHPTTAPSRHAVYHRMVARNRVWLARRNLPAPLV
                     PVYLGVWMLLTLARRPSRPALRAWFGGFREGWTTPCGPRRPMKWRTVWRLTRLGRPPVI
                     "
     gene            complement(19770..20549)
                     /locus_tag="IE325_RS00435"
                     /old_locus_tag="GCM10018780_00860"
     CDS             complement(19770..20549)
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008413838.1"
                     /locus_tag="IE325_RS00435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_00860"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_190067590.1"
                     /transl_table=11
                     /translation="MSRPSVAELRPVVHPAGVKDRRSGEHWMGRLYMREVSLRVDRYLV
                     NTRVTPNQLTYLMTVFGVLAAPALLVPGITGAVLGVVCVQMYLLLDCVDGEIARWKKQY
                     SLNGVYLDRVGAYLTDAAVLVGFGLRAADLWGSGRIDWLWAFLGTLAALGAILIKAETD
                     LVGVARHQAGKPPVQEAASEMRSSGMAMARKAAALLKFHRLILGIEASLLILVLAIADQ
                     VRGDLFFSRLGVAVLAGIALLQTLLHLVSILASSRLK"
     gene            complement(20527..21588)
                     /locus_tag="IE325_RS00440"
                     /old_locus_tag="GCM10018780_00870"
     CDS             complement(20527..21588)
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494151.1"
                     /locus_tag="IE325_RS00440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_00870"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_190067591.1"
                     /sec_met_domain="Fe-ADH (E-value: 2e-22, bitscore: 75.5,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 3.7e-08, bitscore:
                     28.8, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRPGALDDLACVLADERISHSGKLAVAVSG
                     GSGATLRERLAPSLPGATWYEVGGGTLDDAIRLAGEMKAGHYDAVVGLGGGKIIDCAKF
                     AAARVGLPLVAVPTNLAHDGLCSPVATLDNDAGRGSYGVPNPIAAVIDLDVIREAPVRF
                     VRAGIGDAISNINAIADWELANRVKGEKIDGLAAAMARQAGEAVLRHPGGVGDNDFLQV
                     LAEALVLTGVAMSISGDSRPASGSCHEINHAFDLLFPKRAASHGEQCGLGAAFAMYLRG
                     AHEESAYMAEVLRRHGLPVLPEEIGFTDDEFVRAVEFAPQTRPGRYTILEHLDLTTDQI
                     KDIYADYVKAIGS"
     gene            complement(21576..22328)
                     /locus_tag="IE325_RS00445"
                     /old_locus_tag="GCM10018780_00880"
     CDS             complement(21576..22328)
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983099.1"
                     /locus_tag="IE325_RS00445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_00880"
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="WP_086868346.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 7.6e-11, bitscore:
                     38.6, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDSLPKALVPVGPAGIEGEPTVLDLTLA
                     NFAEIGLTEVAIIVGYRKEAVYERKAALEAKYGLKLTLIDNDKAEEWNNAYSLWCGRDA
                     LKDGVILANGDTVHPVSVEKTLLAARGEGRRIILALDTVKSLADEEMKVVVDPAKGMTK
                     ITKLMDPAEATGEYIGVTLIEGDAAPELADALKAVWETDPQQFYEHGYQELVNRGFRID
                     VAPIGDVKWVEIDNHDDLARGREIACQY"
     gene            complement(22325..24133)
                     /locus_tag="IE325_RS00450"
                     /old_locus_tag="GCM10018780_00890"
     CDS             complement(22325..24133)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676195.1"
                     /locus_tag="IE325_RS00450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_00890"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_190067592.1"
                     /transl_table=11
                     /translation="MSTAILTGQPVPGSSIEGDLRSLGYDVRVAADPADAETLLAQVPG
                     DQRVALIDARFVGHQHALRLGLTDPRFPLAAIPGAVTAQAAGRKALTRAMARETSAGGG
                     AAVAVDSLADRVVTALDDDGTDVHRPELGSLVAVVPADPQARNEARQAVASVDDEAVRL
                     KSAVKARDGFFTTYCVSPYSRYIARWCARRGLTPNQVTTASLITALIAAGCAATGTRVG
                     FIAAGLLLIFSFVLDCTDGQLARYSLQYSTLGAWLDATFDRAKEYAYYAGLALGAARGG
                     DDVWALALGAMVLQTCRHVVDFSFNEANHDATANTSPTAALSDKLDSVGWTVWVRRMIV
                     LPIGERWAMIAILTAATTPRITFYALLIGCAFAATYTTAGRVLRSITRKATRTDRAAQA
                     LADLADSGPLSEGLAGLLRKLPARGPLGSRALVALPGAALLVAAAGLSAYGSALPIALA
                     LLYVITSAAAVALPLKGALDWLVPPLFRAAEYGTVLVLAVKAEVNGALPAAFGLVAAVA
                     YHHYDTVYRIRGNAGAPPAWLVRAIGGHEGRTLLVTVLAAVLSASQFTVALTVLAVAVA
                     LVVLVESIRFWVSSGAPAVHDEGEPA"
     gene            24401..25372
                     /gene="galE"
                     /locus_tag="IE325_RS00455"
                     /old_locus_tag="GCM10018780_00900"
     CDS             24401..25372
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (65-184). E-value:
                     7.3e-13. Score: 40.1. Matches aSDomain:
                     nrpspksdomains_IE325_RS00455_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676194.1"
                     /locus_tag="IE325_RS00455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_00900"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_190067593.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 3.6e-18, bitscore:
                     61.7, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.4e-11,
                     bitscore: 40.0, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.3e-11, bitscore:
                     40.1, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLITGGAGYIGAHVARAMTGAGERVLVLDDLSAGYPARLPGDV
                     TLVEGSSLDGDLLKRVFAEHAVTGVVHLAARKQVGESVAQPTRYYRENVGGLTTLLEAV
                     AEAGIKRFLFSSSAAVYGNPDVDLITEDTPCAPVNPYGETKLAGEWLVRAAGRAHGIST
                     VCLRYFNVAGAASPELADTGVFNIVPMIFDRLTRDEAPRIFGDDYPTPDGTCVRDYIHV
                     ADLAEAHLAAARRLTKANDSGDLTVNIGSGEGVSVRELITVIGEVTGDRRPAVVEPRRP
                     GDAPRAVASAALAAERLGWTARRGVREMVESAWAGWRLHHGL"
     CDS_motif       24404..24490
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE325_RS00455_0001"
                     /evalue="7.30E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE325_RS00455"
                     /protein_end="30"
                     /protein_start="1"
                     /score="18.6"
                     /tool="antismash"
                     /translation="TWLITGGAGYIGAHVARAMTGAGERVLVL"
     aSDomain        24596..24952
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE325_RS00455_NAD_binding_4.1"
                     /evalue="7.30E-13"
                     /label="IE325_RS00455_NAD_binding_4.1"
                     /locus_tag="IE325_RS00455"
                     /protein_end="184"
                     /protein_start="65"
                     /score="40.1"
                     /tool="antismash"
                     /translation="AVTGVVHLAARKQVGESVAQPTRYYRENVGGLTTLLEAVAEAGIK
                     RFLFSSSAAVYGNPDVDLITEDTPCAPVNPYGETKLAGEWLVRAAGRAHGISTVCLRYF
                     NVAGAASPELADTGV"
     misc_feature    complement(25422..25436)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     misc_feature    complement(25482..25496)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.91"
                     /tool="antismash"
     gene            25541..26476
                     /locus_tag="IE325_RS00460"
                     /old_locus_tag="GCM10018780_00910"
     CDS             25541..26476
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009339288.1"
                     /locus_tag="IE325_RS00460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10018780_00910"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_190067594.1"
                     /transl_table=11
                     /translation="MGAGHDHGHAHAPTTGTAAAAYRGRLRVALAITLGVMVVEIVGGV
                     VANSLALIADAAHMATDALGLGMALLAIHFANRPPSTTRTFGYARAEILAALANCLLLL
                     GVGGYVLYEAIQRFFTPAATEGGLMIVFGAIGLVANMISLTLLMRGQKESLNVRGAFLE
                     VAADALGSLAVLISAAVILATGWQAADPIASLVIGLMIVPRTLKLLRETLDVLLESAPK
                     DVDMAQVRSHILALDGVEDVHDLHAWTITSGMPVLSAHVVVRSDVLNAIGHEKMLHELQ
                     GCLGDHFDVEHCTFQLEPIGHAEHEARLCH"
     misc_feature    complement(26492..26507)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.58"
                     /tool="antismash"
ORIGIN
        1 ccgacatgaa gtccgtgatg caccagtacg gcacctcggt gaatttcgcc cgtttcaagg
       61 cattggtacg cagctgtcgg gtcgaggccg tgcagccgca gggccggcag gggctcgccg
      121 tagctctggg cctggagcca ggcgaggacg accgtctcgt ccccgaggac gtactgcacc
      181 gcgctcagcc cgcccgtggg cggccgcagc cggtagaggt cgccgcgctg caccagcggg
      241 cggatctcct tgtagagcgc cacccactcc cgggcctcgg cgagttcctc ctcggtccag
      301 cgcgagaggt cgccgccgac cccgaggacc ccggccatgg cgctgacgaa gcggaagcgc
      361 agcgagctgg cacggtggtt gagcatggcg ttcgggctgt cggtgaccca ggcggccatg
      421 gcccgcgcgg ggtggatctg gctgaagccg tgctggatgg cgagccggtc cagggggtcg
      481 gtgttgtccg aggtccacac ctggtccgta cggccgagaa tgccgaggtc gatgcgtccg
      541 ccgccgcccg agcaggactc gaaggcgacc ccggggtgcg cggcgcgcag ccggtcgagc
      601 agggcgtaca ggccccgcac atggtccacc cagaggcgtt gcgggtaggg ctcgccgggc
      661 cagcccgcgt cggtgaaggg gcggttgaag tcccacttca catagtcgat cggggcactg
      721 gagaggagcc cgtcgagctg ctcccagagg tactcctgga cgtcctcacg cgcgaggttc
      781 agtacgagct gattgcggaa ttccgtacgc tttcgtcccg tttgatgctg cgcccagtcc
      841 gggtgggcgc ggtacagctc gctgtccgga ttgaccattt ccggttcgac ccagataccg
      901 aaccgcatgc cgagcgcgtg cacatactcg gcgagcggct tcaggcccga ggggaagcgg
      961 tcggggtttg gcgtccagtc gccgagcccg gcgcggtcgc tggtgcgcgt gccgaaccag
     1021 ccgtcgtcga ccacgaacag ctcgacgccg atggccgcgg cccgccgcgc gaggaggctc
     1081 tgctgctcct cggagatgtc gaactcggtc gcctcccagg agttgaacag caccggccgg
     1141 tcccggtccg cgtccgggat cacatacgcg cgctggtacg cgtgccaggc ccggctcgcc
     1201 ccgccgaagc cgccgtcgct ccacaggccg gcgaagacgg gcgtcgtgaa ggactccccc
     1261 gtcgcgaggc gcagcaggcc cgagtcgtcg tgtccggcac cgccggtgat ctgcacgcgc
     1321 gcgtccggga gttgggccac ggcgatacgc caggacccgg accagccgag ggcgcagccg
     1381 tagacctcgc cgcgttcctc ggtggcgtcc gtgtcgagcg cgacccaggg caggtgctgg
     1441 tgcccggtgt ggccgcggcg gctgccgatg accttctcac cgtaggtgag gggagcccgc
     1501 gccagccggg actcggcgcc ccagcggccg tgcagctggg acagccgcca gtcctcccgg
     1561 tcgggcagcg tccaggtggc cgagtcggcg cgcagcagct ccagggcggg cccctggttg
     1621 tccagggtcg cccagcgctc cacgacgtcc ccgcgcatcc ggtaatgcag ggtgacgttc
     1681 agcccgccgt cacgaaagcg caaccgcagc tcgtcaccct cggtctcgta ccgctcgaaa
     1741 ccccactcgg tgccgcgccg ctcctcggtg cgcaccgaca gggcgggccg tacgaagcgg
     1801 gggccgccct cgacggggta ttcctcgcgt ccgtcgagcg gggactcgaa gggccggtac
     1861 tccggcagcg ggcgtacggc gagggcctcg gcgtcggcga gcgcgatccg gggtccccag
     1921 tgcaggtgca gcagttcgtc ggcgtcggtc aggtggacgg cgtagctgct ggtcggcccg
     1981 gtgaggagcc aggtacggcc gtggtcggag atctccagca tcaagccccc acagagacga
     2041 acaggcgcga tcaagtacca acatcatcaa gggttgatcg gccccacggc aacgcctgtg
     2101 gacaactcat tgccccagga atccatgtcg tatggtcgag agcgcacccc gtcggccgca
     2161 tcgccgagcc gcgccgccgg ggccgaccgg gaggagcccc cgtgacgcag cagatcccgt
     2221 cgaccgagcc cgaactggcc ggggttcgca acttccgtga tgtgggcggc ctgcccacgg
     2281 tggacggacg acgggtgcgc catggagtgc tgttccgcag cggccacctc gcgcacgcga
     2341 ccgccgagga cgccgctttc ctcgactccc tggggctgca cacggtcttc gacttccgta
     2401 acgcggccga ccagaagctg gaggggccgg acgtcgagct gccgggcgtg cgcaatgtga
     2461 acctgccgct gtcggacccg gcggacggcg cggagttctg gaagatggtc cgggacggcg
     2521 atctcgacca gctgcgcgcg atcctggccg acggcaaggg cgcgaaccgg atgatcgtct
     2581 cctaccgttc gatcatcaag gagcgcaccg gcgagcactc ccaggtgctg cactccctcg
     2641 ccgaggacag cgtgccggcg ctgatgcact gcgcggccgg caaggaccgc gcgggtctgt
     2701 ccatcgccgt gacgctgctg gccctcggcg tcgagcggga ggcgatcgtc accgactacc
     2761 tggagtccaa cgccaaacac cgccgctaca aggtgcgccg cagcggcagc ggcgcctccg
     2821 cctactcgcc cgaggtcatg gagctgctca gcccgctgtt cgacgcgcgg gccgaatatc
     2881 tgacggcggc gttcgagacg atcgaggaga cgtggggcgg cgtcgacacc tacctggagc
     2941 agggtctgcg gctgtcaccg gagtcccggg agctgctgcg ggagcggctg ctcgactgag
     3001 gcggcgcgcc ccggcctact tcgcgcccgc ctcgaacagg aagtagatga aggcggcgaa
     3061 gagatgcccc accgcgatgt agatgatcag ccggatccac agcgcgcgcg ggaacctgtc
     3121 ctcggtgttg ctcatggcgt gactccaggg gtggggccca ggcacagcgt ggccgtgggg
     3181 ctctgcagca gggtgtggac gaacagcagc tcgaccccgc cctcgtcctg ggcggcgatg
     3241 cggtgcgggg tgagtgagtc gaagtgcgcg ctgtctccgg gcgcgagccg gtgcgtggtg
     3301 tccccgaggc gcagccgcag ccgcccctgg aggacgtaga gccactcctc gccggcgtgc
     3361 acgcgcacga tgtcgccctg cgagccgtgc ggcacatgga cacgcagggc ctgcatcccg
     3421 cgcccgtgcg cgcccgcctg ccagtaggtc cagccaccgg ccgcggtcgg ttccatgtca
     3481 ccggcgcgca ctacggcgtc ccgctcggcg accgtctcgc cgagcagctc ggagaccgtc
     3541 gtaccgtaga tacgcgcgag tgcgagcagc atcggcagtg agggctggcg ctgcccggtc
     3601 tccaggcggg agaggtgggc gggtgacagt ccggcggcgc gggccgctgc ctccagggtg
     3661 agggcggctc ggcggcgcag ggcgcggagc tggggtgcga cgacgggcag ggcgacctcg
     3721 tgttccgccg agggctccgt ctcggaagag ctcatgcctc cattcagccg gacctttgcc
     3781 tctgaggcaa atttattgcc tcagaggcaa agcccctcgg tcacgctcac ctcaccgatt
     3841 ggcgaccgcc tgcttgacca gcgtctttcc gaagtcccac atcagcccgc ccccgctgtg
     3901 cgcgtcgtcc atcacatcgg tgaaggcgtc gacgaaccgg tccacctccc gctccccgat
     3961 gacgagcggc gggatgagct tgatcacctc caggtggtcg ccggagacct gggtgaggat
     4021 ccggtgccgc tgcagcagcg gtacgacgac catctgggcg aacaatccct tgcgcgcggc
     4081 ctgcagcatg ctccaacggc tgcgcagccc cagcgacttg ggccgcccga attcgatgcc
     4141 gatcatcagg ccccggccgc ggacgtcggc gagcagctcg tacttgtcga tcagcgccgc
     4201 gagccgggac ctcagctgct ccccggtcgc ccgcgcgttc gcgacggtct gctcgttctc
     4261 catcaccgac agcacggcga gtccggccgc catggcctgt gcgttggaac cgaagctcgc
     4321 cgagtggacg agcacgcggt ccatggacga gtagaccttc ttgaagatcc agtccttgcc
     4381 gagggtggcc cccaccggca catagccccc ggaaagcgcc ttggcgacgc acaccaggtc
     4441 cggctcgacg ccctcctcgt gctggtaggc gtagaagtcg ccggtccggc caaggcccgt
     4501 ctgcacctcg tcggcgatga gcagcgcctt gtgcttgcgc agcagttcct gggcggcccg
     4561 cagatagccg ggcggggtct cgtgcacgcc cttgccctgg acgggttcga cgatcagggc
     4621 ggcgacgtcg cccttcttca gctcccgcgc cagggcgtcc agatcgccga gcggaacggc
     4681 cgtgtcgggc aggaggggcg cgaagccgtc ccggaagccg gactcgccgt tgaccgacag
     4741 agagcccgtg gtcagcccgt ggaaggcgtg gtcgcagtac agcaccctcg gcctgccggt
     4801 gacgaaccgc gcgaacttca gcgccgtctc caccgcctcc gtcccgctgt tgccgaagaa
     4861 cacccggtcc aggtgcgggc tgtgcgcgag gagccgctcc gccagcagcc cgggcagcgg
     4921 ctggcagtcg aagcgggtga ggtcggcgag ctgggcgtcg aggacgtcgt gcagcgcctt
     4981 gcggacgacg gggtggtggc gtcccaggcc catcaccccg aacccggcga gcatgtccag
     5041 gtagtcgtcg ccgtccgcgt cccagaagta ggcgccctcg gcccgctcgt agaccttgtc
     5101 gaagccgatg gtgtgcagca tgcgcgggag ctggtggttc agatacttcg agtgcagctc
     5161 atagcgctcg gctccgcgct cggcgaggag ggcgccgagg tcgaactcgc tcgtcattcg
     5221 gctttctcct tgactggcgc gacgatacga cgcacctggc cgccgtcggc ttccttgagc
     5281 gccaggctcg cgctgatccg cccggcgacc tccaccggcg tcagccctat gtccgcgagc
     5341 acctcgcccc gcttggcgtg cgcgaggaac tgctccggga tcccgaaccg ccgcaccggc
     5401 acatccacat cggcgtcgcc cagcgccagc gccacggccg agcccacccc cgacgagcgg
     5461 ctgttgtcct cgacgacggc caccagccgg tgctgtgcgg cgaggggcgc gagcgccggg
     5521 tcgacgggct tcacccaccg cgggtcgacg acggtgcagt tgatgccgcg ggcctggagc
     5581 agctcggccg cctggaggca caccggggcc atcacaccga cggcgacgag cagcacgtcc
     5641 ggctcaccgg cgtcgcggtg cagcacgtcc agcccgccca cccggtcgac cgccgggatc
     5701 gacggcccga cggactcctt cgggaaccgt acgagtgtcg gcgcgtcgtc gcaggccaca
     5761 gcctcgcgca gctgtgcccg cagttggtcg gcgtcacgcg gcgcggcgat ccgaagaccg
     5821 ggcacgacct ggaggatcga catgtcccac atgccgttgt gggaggcacc gtcggcgccc
     5881 gtgacgccgg cccggtccag tacgaacgtc actccgcagc ggtgcagcgc gacgtccatc
     5941 aggagctggt cgaaggcacg gttgaggaag gtggcgtaga tggcgacgac cgggtgcagc
     6001 ccgcccgtcg cgaggcccgc cgccgacacg gccgcgtgct gctcggcgat cccgacgtcc
     6061 cagacccggt ccgggaaccg ctcggcgaac ttgccgagcc cgacggggtg cagcatggcc
     6121 gccgtgatcg cgacgacgtc ctcccgctcc tccccgatcc gcacgatctc ctcgccgaac
     6181 accgacgtcc aggacggccc acccgagggg gcgagcggct cgcaggtcag cgggtccatc
     6241 acgccgacgg tgtggaagtg gtcctcctcg tgggcgaggg cgggttcata gccgcgcccc
     6301 ttctccgtga ggcagtggat cagcaccggc ccgtggaagc gtttcgcgcg cctcagcgcg
     6361 gactcgacgg ccccgatgtc gtgcccgtcg atgggaccga cgtacttcag tcccagatcc
     6421 tcgaacatgc cctgcggcgc gaaggcgtcc ttgaacccct tcttcgcgcc gtgcagggac
     6481 tcgtagatcg tgccgccgac gatcggcgtc cgcaggagga cgtccttgcc ccaggccagg
     6541 accttctcgt agctgtccgt cgtccgcagg gtcgccaggt ggttggcgag gccaccgatg
     6601 gtcggcgcgt acgaccgttc gttgtcgttg acgacgatga tcagcggccg gtccttggcg
     6661 gccgcgatgt tgttcagcgc ctcccaggcc atgccgccgg tcagcgcccc gtcgccgatc
     6721 accgcgacga cgtgcccctt ctccccctgc acctggcggg ccttggcgag cccgtcggcc
     6781 cagccgagcg cggtcgaggc gtgactgttc tcgacgatgt cgtgctcgga ctcctcgcgc
     6841 gaggggtagc cggacaggcc gcccttgccg cgcagcttgg agaagtcctg gcgcccggtc
     6901 agcagcttgt gcacatagct ctgatggccg gtgtcccaga cgatgcggtc gaccggcgac
     6961 tcgaagaccc ggtggagcgc gatggacagt tccaccaccc ccaggttggg cccgaggtgt
     7021 ccgccggtcc tggcgaccgc gtgcaccagg aactccctga tctcttcgga cagttcgcga
     7081 agatccgtct cggacagcgc cttcaggtcg cgtggtcccc ggatgctctc cagaatcgtc
     7141 acgctcgggc ccccttcggt ccgtgctgtt caactcacgg tgacggccgg ctcccccgac
     7201 gcgacgccgt cctgttccat ctgttcggcg atcttcatcg cctcttcgat cagcgtctcg
     7261 acgatcttgg actcggggac ggtcttgatg acctcgccct tgacgaagat ctggcccttg
     7321 ccgttgccgg aggcgacgcc gaggtcggcc tcgcgggcct cgccggggcc gttgaccaca
     7381 cagcccatga cggccacccg caacggcact tccatgcctt ccaggcccgt cgtgacctcg
     7441 tcggccagct tgtagacgtc gacctgggcc cgcccgcacg acgggcagga gacgatctcc
     7501 aggcgccgct gcctgaggtt cagggactcc aggatctgga tgccgacctt gacctcctcg
     7561 gcgggcggag cgctcaggga cacccggatg gtgtcgccga cgccctgcga cagcagcgct
     7621 ccgaaggcga cggccgactt gatcgtgccc tggaaggctg gcccggcctc cgtcaccccg
     7681 aggtgcagcg gatagtcgca ctgcgccgcg agctgcttgt acgcctcgat catgatcacc
     7741 gggtcgttgt gcttcaccga gatcttgatg tcccggaagt cgtgctcctc gaacagcgac
     7801 gcctcccaca gcgcgctctc cacgagggct tccggagtgg ccttgccgta cttctggagc
     7861 agccgccggt ccagcgaccc ggcgttgacg ccgatccgga tcggcgtccc gtggtccttc
     7921 gcggcccgcg cgatctcctt gaccttgtcg tcgaactgct tgatgttgcc gggattgacg
     7981 cgtacggccg cacagccggc ctcgatcgcg gcgaacacgt acttgggctg gaagtggatg
     8041 tccgcgatca ccgggatctg cgacttgcgg gcgatcgtcg ccagagcgtc ggcgtcgtcc
     8101 tgcgtcggac aggcgacccg cacgatctgg cagcccgacg ccgtcagctc ggcgatctgc
     8161 tgcaaggtgg cgccgatgtc cgacgtacgg gtcgtcgtca tcgactgcac cgacaccggg
     8221 gcaccgcccc cgaccgccac cgggccgacc tggatctgcc gcgacacacg tcgctcggcg
     8281 accggccgga ccggtacctc ggggacgccc aaggagatgg cggtcatggc gtcactcccg
     8341 gtttccggag accgtctcgc gcatggcgcg cagcgactcc ttcagcgagc ccatggtggc
     8401 gagtacggcg gtgggttcgt agccgcagtg cgccatgcag ttggcgcagc gcgggtcctt
     8461 gccgcggccg tacttgtccc agtcggtgtc ctcgatcagc tcccggtacg tcgggacgta
     8521 gccgtcgctc atcaggtagc aggggcgctg ccagccgaac agcgagtagt tcgggatcgc
     8581 ccaggcggtg cacgggaagt cgaccttgcc ctcgaggaag tcgaggaaca gcggcgagtg
     8641 attcagccgc cacttcctgc ggttgccgcc cgcgaaggcc ttcttgaaca gctcgcgggt
     8701 ctgctcgacg ccgaggaagt gctcctggtc gggagccttc tcgtaggcat aggcgggcga
     8761 gatcatcatc tcgtcgacct tgaggtcgtc gttgaggaaa ttgagcacct cgacgatggt
     8821 ctgcggggtg tcggtgttga agaaggtcga gttggtggtg acccggaagc cgcgccgctt
     8881 ggcctccttg atcgcctcca ccgcctcgtc gaacacgccc tccttggcca ccgactcgtc
     8941 gtggcgctcg cgcaggccgt cgatgtgcac ggcgaaggcg aagtagggcg agggcgtgaa
     9001 cttgtccatc ttcttgcgca gcagcatggc gttggtgcac aggaagacgt acttccgctt
     9061 ggccaccagc tggcgcacga tctcgtcgat ctgcgggtgc atcagcggct cgccgccggc
     9121 gatggacacc atgggcgcac cggattcgag caccgccccc acggcctggg ccaccggcat
     9181 gcgctgcttc agtactccgg ccgggtgctg gatcttgccg cagccctcgc acttgaggtt
     9241 gcaggcgaac aacggctcca actcgacgat cagcgggaac ttgtcacgcc tgcggagctt
     9301 ctgttcggcc aagtaagtag cgaccttgat ggactgacgc agcggcatgg ccatctggct
     9361 cacctcctgg ggagcagcaa agaacggtgc cattcataga atgcgggtag aacggaacga
     9421 agaacgcgga aagctgatat tccaccgcgc aacgtgccga tccggacgag ttcatgttct
     9481 ggagcgtcca cgaccacccg gacggccgca accgggcgct cgcccgtgcg gacggcgctc
     9541 agaagcgtga ccgccgactc catgtcgacc gcgattgcgc cggtcgcgag cagatcggac
     9601 cgttcctgac cacggacgac atgatcggag ccggtgagcg gtccggtgtg gacggtgcgg
     9661 cccgggatgg tccgcacgag ttctttgacg agtaggtcgg tccccacgca cggaacggtt
     9721 cccgccggat cccgggtctc ctcggcgacc accagatcgc cggggtgcat cccgggggcg
     9781 agccccgcgc agaagccggt ggcgaggacg gcggccccgc tgagggcggg atcggccagg
     9841 acacgggtga cggagcgttc cgccgcccgg ggtcccatgc ccgtacggag caccgtgacc
     9901 ggcccgccgg ctccaccgcg ctcgccggcg cgcagggcga actgctcgat gccgagcgcg
     9961 caggcgatca gcagcggggc cggggcgggc tgtgggctca tcagctcccc ttggcctcgg
    10021 cgagagccgc cccggccttg tcggcgaagg gctctccgtg gacgtaccgg ccgagcgcgg
    10081 tcagcgggaa gacctgccgg tagaggtggt agttgatgga gaagtcccag gggaatccgg
    10141 tgccggtgaa gtacggctcg tcccaggagc cgtcctcgcg ctgggtggcg gcgagccact
    10201 cgatgccgcg ctcggcggcc ttggagtccc gctcccccgc cgcgagcagc gccatcagcg
    10261 cccacgcggt ctgcgaggcg gtcgaggcgc ccttgccgct ccactccttg acgtatttgt
    10321 aggagcgcag gtcctcgccc cagccgccgt cgtcgttctg gacggactcc agccaggtga
    10381 cggcgcgccg gatcgcgggg tgcgagcccg ggatgccggc ggccaccagg gcgggtacga
    10441 cggatccggt gccgtagacg tagttcacgc cccagcgccc gaaccaggag ccgtccggtt
    10501 cctgctcggc gagcagccag cggatgccgc gccgggtgcg cgggtcgtgg gcgaggccct
    10561 cgaccgcgag catctcgacc acgtgcgcgg tgacgtccgc cgagggcggg tcgatgacct
    10621 cgccgaagtc gcagaacggc agccggttgg ggaaggggct ggtgttgtcg acgtcgaagg
    10681 cgccccacgc gccgttgcgc gactgcatcc cgagattcca gcgcaccccg cggccgatcg
    10741 ccttctccac gcgctccgga tcatggtgcc ggacccggcg cagcgcgagg accacctcgg
    10801 cggtgtcgtc gatgtcgggg tagttgtcgt tgtggaactc gaacgcccag ccccccggcg
    10861 gcagttcggg ccgcttgacc gcccagtcgc cgggccggac gatctcctcg cccagcatcc
    10921 agtcggctgc cttgacgagc tgcggatggt cggcgggtac gcccgcgtcc accagcgcga
    10981 tggtggcgag gcaggtgtcc cagaccggcg actggcaggc ctcgatcatc cgggccccgt
    11041 cctcgcgcca cacggcgaag cggtcaaggg acgccagccc ctcgcgcatc acggggtgtt
    11101 cgaggtcgta gccgagcagt cgcagcgcga tgatcgagta caccgccggc ggctggatac
    11161 cgccccagca gccgtcgttc tcctgccgct cgatgatcca gcgggcggcg ctgttcatgg
    11221 cggctctgcg cagcctgcgc ggggcgacct tgcgcagttg gtgcagggct ttatcgagcc
    11281 gctggaaggc gccgtcccaa ctggccaccg gggcaagggg cttgagcgga ttcgggtcgg
    11341 ccgggtcggt gtgcagttcg tccagcggga agggcgcggg ccgtaccggg cgcttcgcgg
    11401 agacgatcgt cagggggact atcgtctgcc gggcccagca cccgaagtcg tagatgttga
    11461 gcgggaacca cttggggaag tagatgagtt ccggcgggag ttcgggcagg tcctcccact
    11521 tccaccagcc gaacagggcc agccagatcc gggtgaagac ccgggaggcg gcgatgccgc
    11581 cctgctcacg gatccaggcg gaggcccgcg ccatgtgcgg ggcgtccggc gcgtcaccgg
    11641 ccaggcgcag ggcgacgtac gcctcgatgg tcgcggagag ttcgccgggg gcgccgtaga
    11701 aggtgcccca ggtgccgtcc tcgcgctgct ccccgcggat gaagagcgcg gcggcccggg
    11761 tggtcttctc gtcgcggatg cccaggaact gacggagcag caggtcctcg gcgtccatgg
    11821 tgacgttcgt ctcgaggtcg cccttccacc agccctgggc gtcctgcttc gccagcagga
    11881 aatcggtggc acgccgtacc gcgtgttcgg cgacctcgtg caccccggcc gccacgggag
    11941 tctcgctgtc ggtgtcgctg gccgcggctg cccggggcgc cggcgccccg gtgcttccgt
    12001 cggtcgtcgc tgtcatggct tccccttcgt gcagtgctcc tggtagtgcg tctgctgtgg
    12061 gtccgccgtc ggccggtgcg cttcttccag cgacaccggc cggcgactac gcgagggcta
    12121 ttcgaccgat actgatcatc tcttttcgcc cgctggtgat catctcttcc gtacgacgac
    12181 gaagtcggcg agcgccgtga accgcgcccg cacctgctcg ggcatgtcga cggcgtcgag
    12241 ggcctcgacg gcgatggtgt gctgtcggcg cgcctccgcg gcggtccact cacggccgcc
    12301 cgcctcctcg atgagggcgg cgcgggcggc gaactcctcc tcggagaagt tctcgaagtc
    12361 gctgctcttg gcgtcggcgg cgaggatctc gccgagccgc tcggaggcgg ggccgcccgc
    12421 cgcgagcgcg gccacgaccg gcagggactt cttgcgctgg cgcagatcgc tccaggtctg
    12481 cttgccggtg gcttccgggt cgccccagat gccgagcagg tcgtcgatgg cctggaaggc
    12541 gaggcccagg tggtagccgt acttctccag ggtgtcggcg gtacggtcgt ccgcgccgcc
    12601 gagcaccgcg ccgatggagc tggcgcaggc cagcagggcg ccggtcttgt tgccctccat
    12661 ctccaggcac tcctcgacgc cgacgcggtc gcggtgctcg aaggagatgt cctgcgcctg
    12721 accgtcgatg agggcgcggg tggcggtggt cagccggcgg gtggcgcggc ccgcctccac
    12781 cgtaccgagc tccagcagca cctcgttggc cagcgcgaac atggcgtcgc cgacgaggat
    12841 ggcctgggcc gggccgtgca ccttccagac ggtgtcgcgg tgacggcgct gctcgtcgcc
    12901 gtccatcagg tcgtcgtgca gcagggagaa gttgtggacc agctcgacgg cgaccgcacc
    12961 ggggatgccg acctcgggcg cggctccggt gatctcggcg gagaggaccg cgagggcggg
    13021 gcgtacggcc ttgccgccgt cgccggccgt ggggttgccg tcggcgtcga tccagccgaa
    13081 gtggtaggcg gaaacggtgt ccatgggagg ggccaggcgg tcgacggccg cccgcagtac
    13141 cggtgtcgtc agggtcctac cgcgctccag gagcgcggtg acgtccaccg cggtctctcg
    13201 agcggccttc gaggccgggg gcacagtggg cacgttctct cctcttgttg cggtaccggg
    13261 ggtgcgggag cctgccgccg tgcgctcgtt cagcatcacg ccgcctcctc gacgctgaag
    13321 aggtggctgg ggcggggccg gcccagggcg ctcagcgcgg cgccggccgc actcacgcca
    13381 ctgcggaccg cactctccat ggtcgcgggc caccctgtgg cggtccacgc tccggccagg
    13441 tagaggccgg atgccttggt acgggcgccg ggccgcagcc gcccgacgcc tggggtggga
    13501 gcgaatgtcg ccgtgcgctc cctggtcacg aagaaatcct tgacgtgcgc gccccgcgcg
    13561 ccgggcaaca gccgttccag ctcgggcaga taccgctcac gcagggcggc gacgggttcg
    13621 tcgatctcgt cctgcgcggc cgactgggac agagcgaggt actggccgtc ccggagcccg
    13681 gaggcctcgg tgcggtcgaa cacccactgc acgggggtgc cgagggccgt gaggaacggt
    13741 gtgctcagca ccttgcggtc gtagacgaca tggacgttca ggatcggcgc cgtgccgatc
    13801 tccaggagct tttcgggggc gtcgagtgcg ccgtcgggca gcaggtcgta cgcctcgcgc
    13861 tgggccacgg cgagcacgac cgcgtccgcg tgcagcgtct caccgggaac ctcgacgctc
    13921 caacgtccgt tctcgtcaga ggagatggag gtgacgcgtg tacggacctc ggtacggacg
    13981 cccgcggtgt cgagcgcctt gcgggccagc cggtcatgca gttcacccag cgggacgtgc
    14041 gcccatccga tgtcggcggc gcccgggtcg gacagcagac cggtcttgaa caccatcgcg
    14101 gcgagcccca gcgaggcgtc gcccgcgacc gcgttgaggg tggcgacccc gaccaggtcc
    14161 cacagggcct cgacggcacg cgccgactga ccgtgcgcgg tcagccagct gccgaagtcc
    14221 tgggtgtcca gggtcggatc ggcgaggtcg agccccttga gcgcgagcgc ggcacggccg
    14281 accttggcgc gttcggcgag ggagagatgc ggataggtcg ccaggctccg gcccaggtgc
    14341 aggggtacgg gcagggcgtc gcgccgcagt ctgccgagcc gtcggccctc gggcttgtcg
    14401 aggtcgagca cgggcacgtc gagacgatcc tggagcggag ccagcgccgt cccctcgatc
    14461 cggtcgagga accagcggta ggcggtgcag cagcgcagat agacgtgctg tccgttgtcg
    14521 acggtcagat cgccgcgctg gaaggagaag gccaggccac ccagcctcgg cctgccctcg
    14581 atcagggtga cccggacgcc cgcgtcggcg agcgcgagtg cggaggtgat gccggcgagc
    14641 ccgccgccga tcacgacggc gtcccgcccc gagtgtcccg ggatgtccgc gagcgacccc
    14701 tccggccgtg tgccctcggt catcgtgcac cctcccctgc gcggccgccg cgccgatggt
    14761 tcaacggtcc acggccggtc gtctcagtca gggacgccgc atgggagcgg agggttgcct
    14821 gccgcttttc gccggtggca tcaccttggg ccggaatgtc catcaggcgc gcctcctgac
    14881 ggttcgggtg acatgccggg cgtccagacc ggacagaccg cgcacggcga cgtacgcctt
    14941 ctcgcgcccg ggcagggaga cccggccgcg cagcacggcc tccgggtcac gctcgatgcg
    15001 gtccaggagt cggcggtaga taccggccat ggcggcgacg caggcgccgc tgcgccggtc
    15061 gagcatgggg agcagccggt agccctcggc gaaaagggcg cgggcccgtc gcacttcgaa
    15121 gtggacgagg cccgcgaagt cggagccctc cggtggggtc ggcccgctga agccggccga
    15181 gcagccgaat ttggcgaggt cgtcggaggg cagataggtg cgccctccct cggcgtcctc
    15241 ccggacatca cgcaggatgt tggtcagctg cagggcgagc ccgagcgtgt cggcgtactc
    15301 gggagcgcgt tcggcgccgc gcgcacccgg ttcggtgccg aagacgccga gcgagagccg
    15361 cccgatggcg ccggccacac agcggcagta ggccttcaga tcgtcccagg tctcgtaggt
    15421 ctccccgcgt acgtccatca ggacgccgtc gatcagctcg tccagtccgc cgagggggat
    15481 cgggaagacg tcggcggcgt gggcgagggc cacggccacg gggtcgacgt cgtcctcgtc
    15541 gacctcacgg tcgcggatcc gggtcagcag ctgacgggtg tcctcgagtc tggcgacctt
    15601 gacgtcgccg gtcagggcgc cgtcgccgat gtcgtcgacg cggcgcgaga acgcgtacag
    15661 cgccgacatg gcgcggcgct tggacgtggg cagcagcctg atgccgtagg cgaagttacg
    15721 ggcctgctgc ccggtgacgg cctcgcagta gctgtaggcg gcgagtaccg gtgcggacgc
    15781 gtgtggtgca gactccacgg tccggatcac ccctctcctc gcagagtcac gcccacctca
    15841 cgcagcagct ggcgcttgct ggccttgggc gggccgggaa gtacgtcgta ttcggcggcg
    15901 gcgatcgcac ggatcgccgc ccttcccccc gccacgaaac ccgcgagcag cagcttgagc
    15961 ctgccgtgga cgctacccac caggggggtg ccttcattca ggaggagccg ggcacgttcg
    16021 gcttcgtatg caaccagtgc gcgcaccgat gcgcccgctg tttctgccgc gagatcggtt
    16081 tcctgcacgt gaaagcgctt catgtccgcc gcgggcagat agatccggtc acggccgaga
    16141 tcctcggcga cgtcctggag gtgctcgacg atctgcagcg cggtgcacac cgcgtcggag
    16201 aggcggatcc gctcgggcgt ctcggtgccg gtgacggcga ggacgaggcg gccgacgggg
    16261 ttggcggaga gttcgcagta ggcaagcaga tcgtcgtagg tctcgtagcg tccgacgagc
    16321 tggtcctggc ggttggcggc gatcaggccg agaaagggct cgggggtgag cgagcggcgg
    16381 cggaccgtcg gctggaggcg gcgcaacagg gggtggctcg gggtgccgtc gaagacgcgg
    16441 cgcaggtcgg cctcgaaggc gtcgagcagg atcaggcggt cctcggcgtc ctcgggcggt
    16501 acgcccagca gtcgggcgtc ggcgccgccg ggagcgagat cgccgtcgcc gatgtcgtcg
    16561 accaggcggg cgaagccgta gacggccatg aggtcggttc gccaggccct gggcaggaag
    16621 aacggggcca cggggaagtt ctccgctgcg gctttgtcga gcgtgccgcg ctccggatcg
    16681 tcggagggcg cgccggttcg gttcaccgtg ggctgcccgg ggcggggacg gcgcaggcgg
    16741 aggcgttgag ctggggagtt tccgtagcca ttgccgtcac atctcccgtt ctacaccgca
    16801 gacccaatgc acactatttc ggacacgccg cccggctgtc cgcgccgcgg cccggagaga
    16861 ggggtgtcgc gccttatcgc cccacttgcc gcgtttcggt accggtacag cttacgttgt
    16921 acaacgcacc gaggcccttg ggggcgtcct gcacatcaca acaacacacc gattgatgtc
    16981 aagattcctg gcaccggccg gagttgacgt ttcctttgca gacgcgggcc ccgccggggc
    17041 agttccggcg gggctccggg aaaggcgctg ggccgcttgg cccatgtccg ggtggactac
    17101 ttgcccgtga acttctcgta ctccttgagg acctcgtcgg tcgggccgtc catgcgcagc
    17161 tcgccgcgtt ccagccacag cacgcggttg caggtgtcgc ggatcgactt gttgttgtgg
    17221 ctgaccagga acaccgtgcc ggcttccttg cgcagttcac ggatgcggtc ctcggagcgc
    17281 ttctggaact tgcggtcgcc ggtggccagc gcctcgtcga tcatgaggac gtcgtggtcc
    17341 ttggcggcgg cgatggagaa gcgcagccgg gccgccatgc cggaggaata ggtgcgcatg
    17401 ggcagggtga tgaagtcgcc cttctcgttg atgccggaga aatcgacgat gccctggtag
    17461 cgctccttga tctgctcgcg ggtcatgccc atggcgagcc cacccaatat gacgttgcgc
    17521 tcgccggtga ggtcgttcat cagtgccgcg ttcacaccga gcagggaggg ctggccgtcg
    17581 gtgaagacct tgcccttctc tggcgggagc agtccggcga tggcgcgcag cagggtggac
    17641 ttgccggagc cgttggagcc gatcaggccg atggcctcgc cccggtaggc gacgaaggag
    17701 acgccgcgta cggcgtgcac cttgcgtacg ccccgctcct cgccgcgctt catgatgcgg
    17761 ctgagggcgg cggtggcgct gcccttgccg gacttggcgc cgttgacgcg gtagacgatg
    17821 tgcagctcgt ccgcgatgac ggtggggatg tgcgcatccg ccctctgctc agccacggcc
    17881 gtacctctcc tccgccttcc agaagtacac gaagccgccg accgcgaaca gcacggccca
    17941 tccggcggcc gccgcccaga cgtggtcggg cagctgcgtg tggtcgtagc cgtcgatgag
    18001 agcgaagcgc atcaggtcca tgtagaccgc ggccgggttc cactgcagga cggtggcgat
    18061 ccagtctggc ttgcccttga gcatgatcgg gatggagaac atcaccccgg acgcgtacat
    18121 ccacgtacgc atcacgaacg gcatcagctg cgccaggtcg ggggtcttgg cgccggcgcg
    18181 ggccatgatc agggcgaggc cggtgttgaa gaggaactga aggaccagca ccggcaggat
    18241 cagcacccag ctgagcttcg gatagctgcc gaagccgatc gccacgacga acagcacgat
    18301 catcgagtac agcagctgct ggagctgctg gagcgcgaag gagatgggga gcgacgcgcg
    18361 cgggaagtgc agtgcgcgca ccaggcccag gttgcccgag atcgcgcgga cgcccgccat
    18421 caccgagctc tgggtgaagg tgaacacgaa gacgccggtg accaggaacg ggatgtacac
    18481 ctcgcggggc atgccccggt cggcctggag gatcacgccg aagatgaaga agtacacggc
    18541 cgcgttcagc agcggcgtgg ccacctgcca gagctggccg agcttcgcct ggctgtactg
    18601 ggcggtcagc ttcgcccgcg agaacgcgag gatgaagtgc cgccggtccc agagctgacg
    18661 gacgtactcg aacagcgagg gccgggcgcc gctcacagcg agcccgtact tggcggccag
    18721 ctgggccgcc gtgagtccct cgtcgggcga cggcggcgcg ctcaccgcga ccgagccgtc
    18781 gtgcgttgtc tcactcacca gttgaaactt tcgtcttcga gatgcgcaga ctgtgcgggc
    18841 ctggcatgaa cctggggccg tcgggcccgg tcactctcag ggtcgagctt gtcagatgac
    18901 gggaggtcgg cccagtcgag tcagccgcca caccgtacgc cacttcatgg gcctgcgggg
    18961 accgcacgga gtggtccagc cttccctgaa tccgccgaac catgcccgga gggcggggcg
    19021 ggaggggcgc cgggccagcg tgagcagcat ccagacgccc agatagaccg ggacaagggg
    19081 ggcggggagg ttgcggcgag cgagccagac gcggttgcgg gccaccatgc ggtggtagac
    19141 cgcgtgccgc gagggcgcgg tcgtcgggtg gaacagcacc atgtccgacc ggtaatcgat
    19201 catccagccc gcgtcgaggg cccgccatgc aaggtcggtt tcctcgtggg cgtagaagaa
    19261 ttcgtccggg agtccgccga cttcggcgaa gacctgggtg cgtacggcgt tggcgccgcc
    19321 gaggaaggtg gtgacccggg aggagcgcat cgggtcggcc gcgcgcagcc gggggacgtg
    19381 gcggcgctgg gtgaccccgg tgtcggggtc ggcgatacgg aagctgacga tgccgagctt
    19441 cgggtctgcc gtgaaggcct cgcggcagag ttcggcggtg tcgtggtggg cgaggaggcc
    19501 gtcgtcgtcg aggaagagca atatgtcgac gtcgcggccg ctggggccga atgcctctat
    19561 gccgacgttg cggccgccgg ggatgccgag gttctcgggc agctcgatgg tgcgcacgcc
    19621 ctcggggacg tcgggcaccg gggagccgtt gccgacgacg accacctcga ccttgtcgcc
    19681 gtcctgcttg gcgaccgagt cgagcagggc ccgtagctcg tcggggcggt tgcccatggt
    19741 gatgatcacc gcgccgacct tcacgccggt cacttcagcc tgctggaggc gaggatggac
    19801 acgaggtgca gcagggtctg gagcagggcg atgccggcga gcacggcgac gccgagccgg
    19861 gagaagaaca ggtcgccgcg gacctggtcg gcgatcgcca ggaccaggat cagcagcgag
    19921 gcctcgatgc cgaggatgag gcgatggaac ttcagcagag cggcggcctt gcgggccatc
    19981 gccatgccgg aagagcgcat ctcggacgcg gcctcctgca ccggcggctt gccggcctgg
    20041 tggcgggcga cgccgaccag gtcggtctcg gccttgatca ggatcgcgcc gagcgcggcc
    20101 agcgtgccga ggaaggccca cagccagtcg atacggccgc tgccccacag gtcggcggcg
    20161 cgcagcccga atccgacgag cacggcggcg tcggtgaggt aggcgccgac ccggtccagg
    20221 tagacgccgt tgagcgagta ctgcttcttc cagcgggcga tctcgccgtc gacgcagtcc
    20281 aggaggagat acatctggac gcacaccacg cccaggacgg cgcccgtgat ccccggcacc
    20341 aggagcgccg gggccgcgag cacaccgaag acggtcatca ggtacgtgag ctggttgggc
    20401 gtgaccctgg tgttcaccag gtagcggtcg acccgcaggg acacctctcg catgtagagg
    20461 cgtcccatcc agtgctcacc gctgcgccgg tccttcaccc ccgcggggtg aacgacgggg
    20521 cggagttcag ctaccgatgg ccttgacata gtcggcgtag atgtccttga tctggtcggt
    20581 tgtcaggtcg aggtgttcga ggatcgtgta gcggccgggc cgggtctgcg gagcgaactc
    20641 cacggcgcgg acgaactcgt cgtccgtgaa gccgatctcc tccggcagga ccggcagacc
    20701 gtgccgacgc agcacctcgg ccatgtaggc cgactcctcg tgggctccgc gcagatacat
    20761 cgcgaaggcc gcgcccaggc cgcactgctc gccgtggctc gcggcacgct tggggaacag
    20821 caggtcgaag gcgtggttga tctcgtggca cgagcccgag gccgggcgcg agtcgccgga
    20881 gatcgacatg gcgacgccgg tgaggaccag cgcctcggcg aggacctgga ggaagtcgtt
    20941 gtcgccgact ccgcccgggt gccggagcac ggcctcgccg gcctgtcggg ccatggcggc
    21001 cgcgaggccg tcgatcttct cgcccttgac gcggttggcg agctcccagt cggcgatcgc
    21061 gttgatgttg gagatcgcgt cgccgatgcc cgcgcgcacg aaacgcaccg gggcctcgcg
    21121 gatgacgtcg aggtcgatga cggccgctat cgggttgggc acgccgtacg atccgcggcc
    21181 cgcgtcgttg tcgagggtcg cgacgggcga gcacaggccg tcgtgcgcga ggttcgtcgg
    21241 tacggcgacc agcggcaggc cgacccgcgc cgcggcgaac ttggcacagt cgatgatctt
    21301 gccaccgccg aggccgacga ccgcgtcgta gtggccggcc ttcatctcgc cggccagccg
    21361 gatcgcgtcg tcgagagtgc caccgccgac ctcgtaccag gtggcaccgg gcagcgaggg
    21421 agcgagccgc tccctgagcg tcgcgccgga tccgccgctg acggcgacgg cgagcttgcc
    21481 ggagtgcgag atgcgctcgt cggcgagcac acaggccagg tcgtccaggg cacccgggcg
    21541 aatgtcgacg acgaccggcg agggaatcag ccgggtcagt actggcatgc gatctcccgt
    21601 ccgcgggcga gatcgtcgtg gttgtcgatc tcgacccact tgacgtcgcc gatcggcgcc
    21661 acgtcgatgc ggaagccgcg gttcacgagc tcctgataac cgtgctcgta gaactgctgc
    21721 gggtcggtct cccacacggc cttgagggcg tcggccagct cgggggcggc gtcgccctcg
    21781 atgagggtga cgccgatgta ctccccggtg gcctcggcgg ggtccatcag cttggtgatc
    21841 ttcgtcatgc ccttggcggg gtcgacgacg accttcatct cctcgtcggc gaggctcttc
    21901 accgtgtcca gggcgaggat gatgcgacgg ccctcaccgc gggcggcgag cagcgtcttc
    21961 tcgacggaga ccgggtggac ggtgtcgccg ttggcgagga tcacgccgtc cttgagggcg
    22021 tcacgtccgc accacaggga gtaggcgttg ttccactcct cggccttgtc gttgtcgatg
    22081 agggtgagct tgaggccgta cttcgcctca agggccgcct tgcgctcgta caccgcttcc
    22141 ttgcggtagc cgacgatgat cgcgacctcg gtcagcccga tctcggcgaa gttcgccagg
    22201 gtcaggtcga gaaccgtggg ttcgccttct atgcccgcgg gccccaccgg caccagagcc
    22261 ttgggaaggc tgtcggtgta ggggcgcaga cgccgtccgg cgccggccgc cagcacgagg
    22321 ccgatcatgc gggttctcct tcatcgtgta cggcgggcgc cccggaggac acccagaagc
    22381 ggatgctctc gacgagcacc acgagggcga cggccacggc gaggaccgtg agcgcgaccg
    22441 tgaactgcga ggcggagagc accgcggcga gaacggtgac gagcaacgtc cgtccttcgt
    22501 gccccccgat ggcgcgcacc agccaggccg gcggcgctcc ggcgttgccg cggatgcggt
    22561 acaccgtgtc gtagtgatgg taggcgacgg cggccaccag tccgaaagcc gcaggaaggg
    22621 ctccgtttac ctcggcttta actgcgagga cgaggacggt gccgtactcg gcggcccgga
    22681 acaggggcgg gaccagccag tcgagggcgc ccttgagggg cagggcgacg gctgcggccg
    22741 aggtgatgac atagagcagg gccagggcga tcggcagcgc gctgccgtac gccgagagcc
    22801 cggcggccgc gacgagcagc gccgcgcccg gcagcgcgac cagggcgcgg gagccgagcg
    22861 gcccgcgggc gggcagcttc ctcagcagcc cggcgaggcc ctcggagagc ggcccgctgt
    22921 ccgcgaggtc cgccagcgcc tgcgccgcgc ggtccgtccg tgtcgccttg cgtgtgatgg
    22981 acctcagcac gcggcccgcc gtcgtatagg tcgcggcgaa ggcgcagccg atgaggagtg
    23041 cgtagaaggt gatgcgcggg gtcgtggccg ccgtcaggat cgcgatcatc gcccagcgct
    23101 cgccgatggg cagaacgatc atccggcgca cccagaccgt ccagccgacg ctgtcgagct
    23161 tgtcggagag tgctgcggtg gggctggtgt tggcggtggc gtcgtggttg gcctcgttga
    23221 aggagaagtc cacgacatgc cggcaggtct ggaggaccat cgcgccgagg gcgagggccc
    23281 agacgtcgtc gccgccgcgg gccgcgccga gggcgaggcc ggcgtagtag gcgtactcct
    23341 tggcgcggtc gaaggtggcg tcgagccagg cgccgagcgt ggagtactgc agggagtagc
    23401 gggccagctg gccgtcggtg cagtccagga cgaacgagaa gatcagcagc aggcccgccg
    23461 ctatgaagcc gacccgggtg ccggtggccg cgcagcccgc cgcgatgagc gcggtgatca
    23521 gggaggcggt ggtgacctgg ttcggggtca ggccccggcg ggcgcaccag cgggcgatgt
    23581 agcgggagta cgggctgacg cagtaggtcg tgaagaagcc gtcgcgggcc ttcacggccg
    23641 acttcaggcg tacggcctcg tcgtcgacgg aggcgacggc ctgccgcgcc tcgttgcggg
    23701 cctgcgggtc ggccggaacg acggcgacca ggctgccgag ctcggggcgg tggacgtcgg
    23761 tgccgtcgtc gtccagggcg gtgacgacgc ggtcggcgag gctgtcgacg gcgaccgccg
    23821 caccgccgcc cgcggaggtc tcgcgggcca tggcgcgggt cagggccttg cggccggccg
    23881 cctgggcggt cacggcgccc gggatcgcgg cgagcgggaa gcgcgggtcg gtcagaccga
    23941 ggcgcagcgc gtgctggtgg ccgacgaagc gggcgtcgat cagggcgacg cgctggtcgc
    24001 cggggacctg ggcgaggagc gtctcggcgt cggccgggtc ggcggcgacc cgcacgtcgt
    24061 agccgaggga ccgcagatcg ccctcgatcg acgatccggg gaccggctga ccggtgagga
    24121 tggcggtcga caaccgaact cactccctgt acgtgggtgg cagcgcctgt tggccggggc
    24181 cgtgtcaaat gcctggccgg gcggcgtgtc ggcagaggct atcggatgat tggaagccaa
    24241 cgttcaccgg ccgttcggcg aagcgatcgg caggatttgc cgaaacccgg ccgcgatcat
    24301 catcagggat ctcagggccg ccccacaaac tcgtgcgtac agaacggggc atcggcgaca
    24361 ttgcgcagcg cgcgaagggc tgcgcatagg gtgggcgacc atgacatggc tgatcacagg
    24421 cggagccggc tacatcgggg cacatgtggc gcgggccatg accggcgccg gggaacgcgt
    24481 gctcgtactg gacgatctct cggccgggta tcccgcgcgg ctcccgggag acgtcacgct
    24541 ggtcgagggc tcgtcgctgg acggtgacct gctgaagcgg gtgttcgccg agcacgcggt
    24601 gacgggtgtg gtgcatctcg cggcgcgcaa gcaggtcggt gagtccgtgg cgcagcccac
    24661 gcgctactac cgggagaacg tgggcggtct caccacgctc ctggaggcgg tcgcggaggc
    24721 ggggatcaag cggttcctgt tctcgtcgtc cgccgccgtc tacggcaacc ctgatgtgga
    24781 tctcatcacg gaggacactc cgtgcgcgcc ggtgaatccg tacggcgaga ccaagctcgc
    24841 cggggagtgg ctggtgcgcg cggccggccg ggcacacggg atctccaccg tatgtctgcg
    24901 ctatttcaac gtcgcgggcg ccgcctcgcc ggagctggcc gacacgggcg tcttcaatat
    24961 cgtcccgatg atcttcgacc ggctcacccg tgacgaggct ccgcggatct tcggcgacga
    25021 ctatccgacg ccggacggca cctgcgtccg tgactacatt cacgtcgccg atctcgccga
    25081 ggcgcatctg gcggcggccc ggcggctcac gaaggcgaac gacagcggcg atctcacggt
    25141 caacatcggc agcggcgagg gcgtctccgt gcgcgagctg atcaccgtca tcggcgaggt
    25201 gaccggcgat cggcgccccg ccgtcgtcga gccccggcgc cccggggacg ccccgcgcgc
    25261 ggtcgcctcg gccgcgctgg ccgccgagcg gctcgggtgg acggcccggc gcggggtacg
    25321 cgagatggtc gagtcggcgt gggcgggctg gcggctgcac cacggtctct gatcaagcgc
    25381 accaccctga cctgcggatc gtttccgcag gtcagggcac atgacaacgg tgttcagtgc
    25441 cgcgttgccc gatacccccc acccgtagtt cactgtgatc ccgggacgga aattccgatc
    25501 gtccgacgga tgcggtacgg acactgaagg gcggctttcc atgggggctg ggcacgatca
    25561 cgggcacgcg cacgcgccga cgaccggtac ggcggccgcg gcgtaccgcg ggagactgcg
    25621 ggtcgcgctg gcgatcacgc tcggcgtcat ggtggtcgag atcgtcggcg gcgtggtcgc
    25681 gaactcgctg gccctgatcg cggacgcggc gcacatggcg acggacgcgc tgggcctggg
    25741 catggccctg ctggcgatcc acttcgcgaa ccgtccgccg agcacgacac gcaccttcgg
    25801 ctacgcccgt gcggagatcc tcgccgccct cgccaactgt ctgctcctgc tgggcgtcgg
    25861 cggctacgtg ctgtacgagg cgatccagcg gttcttcacg cccgcggcga cggagggcgg
    25921 cctgatgatc gtgttcggtg cgatcggcct ggtcgcgaac atgatctcgc tgacgctgct
    25981 gatgcgcggc cagaaggaga gcctgaacgt gcgcggcgcc ttcctggagg tggccgcgga
    26041 cgcgctgggc tcgctcgcgg tgctgatctc ggcggcggtg atcctggcca ccggctggca
    26101 ggccgccgac ccgatcgcct cgctggtcat cggcctcatg atcgtgccgc gcacgctgaa
    26161 gctgctgcgc gagaccctgg acgtactgct ggagtcggcc cccaaggacg tcgacatggc
    26221 gcaggtccgg tcccacatac tggcactgga cggcgtggag gacgtacacg atctgcacgc
    26281 gtggacgatc acgtccggga tgccggtgct gtcggcgcat gtggtggtgc gctccgacgt
    26341 cctgaacgcg atcgggcacg agaaaatgct gcacgagctc cagggctgcc tcggcgacca
    26401 cttcgacgtg gagcactgca ccttccagct ggagccgatc gggcacgccg agcacgaggc
    26461 gcggctgtgc cactgaggcg gggcttcagc agtgaaacaa ccgtacggtc cgacaacacg
    26521 tcagtacggg cggaatgcag cgatccggtg gtccgtggcg tcttcacgcc cacagcgctc
    26581 ccgtcgacgg ttccgtaccc gccgcgccgg gcacgatcaa ctgccgggag tgccggattc
    26641 gtacggcaca cttggggcgc aagaccaatg tgaaggatgg gtatgccgac cacgcctggc
    26701 accacg
//
