LOCUS       NZ_BNAU01000013        26012 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Amycolatopsis deserti strain CGMCC 4.7677 sequence13, whole genome
            shotgun sequence.
ACCESSION   NZ_BNAU01000013
VERSION     NZ_BNAU01000013.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Amycolatopsis deserti
  ORGANISM  Amycolatopsis deserti
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 200256)
  AUTHORS   Sun,Q. and Zhou,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 82X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014653945.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:43:30
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,561
            CDSs (total)                      :: 7,498
            Genes (coding)                    :: 7,407
            CDSs (with protein)               :: 7,407
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 32 of 91
            Pseudo Genes (incomplete)         :: 64 of 91
            Pseudo Genes (internal stop)      :: 8 of 91
            Pseudo Genes (multiple problems)  :: 12 of 91
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:49:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 72871
            Orig. end                         :: 98883
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BNAU01000013.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26012
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26012
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26012
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16012](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16012
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(899..913)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.25"
                     /tool="antismash"
     misc_feature    complement(1062..1076)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    1508..1523
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.98"
                     /tool="antismash"
     misc_feature    1922..1937
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.64"
                     /tool="antismash"
     gene            1958..2545
                     /locus_tag="IE290_RS36065"
                     /old_locus_tag="GCM10017786_73130"
     CDS             1958..2545
                     /EC_number="5.2.1.8"
                     /GO_function="GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020421287.1"
                     /locus_tag="IE290_RS36065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_73130"
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="WP_191249219.1"
                     /transl_table=11
                     /translation="MRNAGKIVLAAAAALALGACAPDQDPSSFPPGGGPTYPAPEPAGA
                     SASASAGHGTGSAAHECTADDITVTGDFGAKPTITIPDDCGAPTKLLTKDLKPGTGATA
                     HAGSTLQMDYDLVTWSDKVDQQNSFGAAPFSFALGEGTAIPGWDQGLEGIKQGGRRLLV
                     IPPDLGYGARGNGPIKPNETLVFVVDAVQVTG"
     gene            2864..3622
                     /locus_tag="IE290_RS36070"
                     /old_locus_tag="GCM10017786_73140"
     CDS             2864..3622
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (6-169). E-value: 5.1e-15. Score:
                     47.8. Matches aSDomain:
                     nrpspksdomains_IE290_RS36070_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020421286.1"
                     /locus_tag="IE290_RS36070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_73140"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_191249220.1"
                     /sec_met_domain="adh_short (E-value: 6.3e-32, bitscore:
                     104.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVRGAVAVVTGASSGIGAATALRLHEAGARLVLHGRDGDRLAAL
                     AERTGGVAVRADFAEPGAVEAAAAEITRAGRIDVLVNNAGLGYAGPVSGMSGADVRRLL
                     SVNLAAPVELTRALLPDLLDRPRAAVVFVTSIAGRAGVAGESVYSATKAGVDVFAESLR
                     LELAGTGVRVGVVVPGVVDTEFFARRGRPYQRRSPRPVPAGKVADAVLEAITAERAEQY
                     VPRWLRLPIAVRATAPSVYRALSARFGGSS"
     aSDomain        2882..3370
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE290_RS36070_PKS_KR.1"
                     /evalue="5.10E-15"
                     /label="IE290_RS36070_PKS_KR.1"
                     /locus_tag="IE290_RS36070"
                     /protein_end="169"
                     /protein_start="6"
                     /score="47.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAVVTGASSGIGAATALRLHEAGARLVLHGRDGDRLAALAERTGG
                     VAVRADFAEPGAVEAAAAEITRAGRIDVLVNNAGLGYAGPVSGMSGADVRRLLSVNLAA
                     PVELTRALLPDLLDRPRAAVVFVTSIAGRAGVAGESVYSATKAGVDVFAESLRLELAGT
                     "
     CDS_motif       2888..2974
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE290_RS36070_0001"
                     /evalue="6.70E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE290_RS36070"
                     /protein_end="37"
                     /protein_start="8"
                     /score="15.6"
                     /tool="antismash"
                     /translation="VVTGASSGIGAATALRLHEAGARLVLHGR"
     gene            3665..4636
                     /locus_tag="IE290_RS36075"
                     /old_locus_tag="GCM10017786_73150"
     CDS             3665..4636
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020421285.1"
                     /locus_tag="IE290_RS36075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_73150"
                     /product="DMT family transporter"
                     /protein_id="WP_191249221.1"
                     /transl_table=11
                     /translation="MLVPVFLGFAAAFLFAASAALQRRAVIEVADTEAGGRAARHRVPV
                     LWLIRKLLRKRVWLAGWATNLLGFFSQAAALHFGSIALVQPLLVTELLFALPMASAAIK
                     RWPPLRDWLAGLAITGGVVVFLTVEGTAPLGGSPDQGRLLIAVLIAAATVVTLVQVAQK
                     RGPLLHSALIATAAGICYAISAAMMKVTTDLLLNEGVAHTALTWPGYVLALSTLSGLLL
                     GQQAYGSGSLSAAIAVMSIVNPAASYFLGLLAFNATLVTEPGPLAATAGAAVLLIVGVF
                     GLAHSPSVQAETSRSAQRGVYPGSGKFSGTVPARSSDSFAQE"
     misc_feature    3668..3670
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            4747..5433
                     /locus_tag="IE290_RS36080"
                     /old_locus_tag="GCM10017786_73160"
     CDS             4747..5433
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017983018.1"
                     /locus_tag="IE290_RS36080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_73160"
                     /product="hypothetical protein"
                     /protein_id="WP_191249222.1"
                     /transl_table=11
                     /translation="MHHRASSGERHLVIEIPHLRKTIKDAAILLLETVVIPSVLLALLL
                     NFVGLVPALCAVLGWAAVVIGARRLMKRDMPRTLLLCTAMLVGRAAVALVTSSAVVYVL
                     QPAVGSVLMFLIFVGSAMIGRPITARLAKDFVRLPAELFKHRTVNRVFIEVALLWGGSR
                     LIDAAMTIGFLHWGVGAGLMSRGILSGLLTALTVAACVGHGWRKLRRDGVTLRLAGRHT
                     PAPAAA"
     gene            complement(5475..5927)
                     /locus_tag="IE290_RS36085"
                     /old_locus_tag="GCM10017786_73170"
     CDS             complement(5475..5927)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017983017.1"
                     /locus_tag="IE290_RS36085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_73170"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_191249223.1"
                     /transl_table=11
                     /translation="MQRTNFGGMACSIARTLDVIGEPWSPLVLRDVWAGLSRFEQIQAD
                     LGISRKVLTERLNHLVERGVLERRPYDRRPRYEYVLTQKGAELVEVLMVMANWGDRWLA
                     GEAGPPVVYRHHACGEVSGAGLRCDHCGEALHAGNVDLLPGPGAAA"
     gene            6016..6603
                     /locus_tag="IE290_RS36090"
                     /old_locus_tag="GCM10017786_73180"
     CDS             6016..6603
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020421282.1"
                     /locus_tag="IE290_RS36090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_73180"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_191249224.1"
                     /transl_table=11
                     /translation="MSKVIAAHAVSVDGFITGRDPQPGHGLGDGGMLFDWYFGGDTPSG
                     VFDGFWLSEPSARVFDALAGRVGAIVAGRTTYEDSERFGGGSPHPKARLVVLSHRPAQT
                     SDRQILAAGIEDAIARAREAAGDLDVGLMGGGVVTAALAAGLVDEIVLHQVPVLLGAGR
                     PYFRELPAHVRLRLVEAVPAPGVTHLHYAVER"
     gene            6679..8640
                     /locus_tag="IE290_RS36095"
                     /old_locus_tag="GCM10017786_73190"
     CDS             6679..8640
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025736.5"
                     /locus_tag="IE290_RS36095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_73190"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_191249225.1"
                     /transl_table=11
                     /translation="MVADARAAAVPRPSWWGELLLGLALFGVYLLVEAFPLPGREPRAH
                     ANGEALLAFERWMHLDFELPVNLWLAEQGWIRVFANYEYAITYIASAIILLIWVHARHP
                     VYYRSVRNSFVWLNLFALACFWLFPVAPPRMLEGAGFIDTVRLGHTFLSWGSPALQGAN
                     QLAAMPSLHVGWALWVSVVLARIRGGWLVQIVSAVHVAITFAVIIATGNHYWIDAAAAV
                     VFIAAATWIARLARPVDRVSASDTFFLHVETPAYPQHVGGLIMLDTSANPSGPTREWVQ
                     NAIRDKLPAMPRYAQRLSDYSPWRRQHWVPHPDIDWDWHVPDFDLTRPDGTPGGMGELH
                     RLVARFQSEPLPRDRPLWRFAVVRGVEENTAAVISLVHHAVADGIGTISLMLELFDSPS
                     LLEGINETRQPNALQKAAAGAVGLAQLATDGRPKAQLPSGDPPDRRYATLQIPLDDVRE
                     LARKHGVRVTDLLLGGVAGALRRVAVAPLPESMLTSVTLMAAEPRPGAEGNVTAAVMVD
                     IPLGDMPEAERLKRIARATKRLRTGTRVVASRFVQHTLAGLMPPFFHSWFARTVYNERF
                     FNGTVSNMPGAAWQVSFRDFPLRTAFAIIPLAPGTPFTVGVLGWYGSFSMSATVDAALV
                     DSVDGFLAEFRAVLAELD"
     gene            complement(8648..9865)
                     /locus_tag="IE290_RS36100"
                     /old_locus_tag="GCM10017786_73200"
     CDS             complement(8648..9865)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020421281.1"
                     /locus_tag="IE290_RS36100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_73200"
                     /product="CdaR family transcriptional regulator"
                     /protein_id="WP_229874916.1"
                     /transl_table=11
                     /translation="MAGRRTETSEGTLAELAAATSKRLPRMLDDVARLLNEHWPDYAEF
                     IVTERDEVLVSATMFLQRLLRMAKWDIAELSGIADQAGDRFGEQPLFEEIGRAQWQQGR
                     DLTSLLSAYQIGARVAWHHVAEVALEVGVPSDMFASLAEAVFIFVDQLSSASARGYVLE
                     QSESAAMRERLRDELADMLLSDRSDSAAIRAAAARVDWPLPRQAAVVLVEPDNPVGSAL
                     LGRLGNSSLHVRRQRLVCAIVPDPDGPQRRQRLASALRGAGAVVGHAVPLEHLPASMHV
                     AELAAQLRRTHVLEDDPVFVDEHLDSIIVHRDAKLFDAMRHQCLAPLAHLGPVTRKRLC
                     ETLACWLRHLGDRRAMAEELHIHPQTVRYRMTQLRELFGESLDDPDNRRRLTLALAWGG
                     PESGDL"
     gene            10001..10897
                     /gene="hpnC"
                     /locus_tag="IE290_RS36105"
                     /old_locus_tag="GCM10017786_73210"
     CDS             10001..10897
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020658530.1"
                     /locus_tag="IE290_RS36105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_73210"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_191249227.1"
                     /sec_met_domain="phytoene_synt (E-value: 3.5e-37, bitscore:
                     121.7, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 9.3e-43,
                     bitscore: 140.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPAPPGPGTVGDRALREKEHAENFPVALRILPRDLRADLVAVYD
                     VARVIDDLGDESAVQDRTPGLLRFQRDLERTFRGEQPHERVLRDLLPAIRRRELELDPF
                     NRLVRANLQDQRVAAYATQAELEDYCVLSADPVGRIVLRVFGVRDPVAERLSDRVCTAL
                     QLIEHCQDVAEDRRNGRVYLPQADLAAFGATEADLDAPTTSRPVRLTVAAQTARALDLL
                     TEGAALLDRLHGWARLAVAGYIAGGLATLDALRRARWDVLAGTPRPRKTDVLAHLIALL
                     VRPAAHVRRIREGGRLS"
     misc_feature    10196..10198
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    10259..10261
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            10894..11754
                     /gene="hpnD"
                     /locus_tag="IE290_RS36110"
                     /old_locus_tag="GCM10017786_73220"
     CDS             10894..11754
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017983012.1"
                     /locus_tag="IE290_RS36110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_73220"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_191249228.1"
                     /sec_met_domain="phytoene_synt (E-value: 2.9e-63, bitscore:
                     207.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 8.9e-71,
                     bitscore: 232.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPTIEQAYATCEDITRTEARNFYWGIRLLTRQRRSALCAVYAL
                     ARRVDDIGDGDLPVEEKAARLETVRKELAALDRSTDPVMVAVADAARRYPVPLEAFEEL
                     LDGVWMDIEGRRYGTFDELTEYCRCVAGSIGRLCLGVFGHKPHPRATHYADALGIALQQ
                     TNILRDIREDLLNGRVYLPQEDLDAFGVELRIDNGALADPDGGLANLIRHSAARAREWY
                     ADGLRLGPLLDRRSGACCLAMAGIYRQLLERIADQPSAVYDQRLSLSGREKLGVAVRAL
                     GGRAA"
     gene            11751..13106
                     /gene="hpnE"
                     /locus_tag="IE290_RS36115"
                     /old_locus_tag="GCM10017786_73230"
     CDS             11751..13106
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020421278.1"
                     /locus_tag="IE290_RS36115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_73230"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_191249229.1"
                     /transl_table=11
                     /translation="MRQRVAVVGGGLAGITAALRCADAGHEVTLLESRGLLGGLTHSFT
                     RDGLHVDNGQHVFLRCCTAYLGFLRRLGVTDRVHLQPRLEIPVHSPRLRRPVWLRRNPL
                     PAPLHLADSVLRYTPLGLGDRMRFAGAALALKSVDPAAPSSDRRTFGEWLAAHGQSRDA
                     IRKLWDLVGIATLNAPAEQASLGLAATVFQVGLLTDADAADIGWATVPLRKLHGEPALA
                     RLTEAGVTVRLNTKVTGLSRADGVWRVEAGEPVEADQVVLAVPPPAAAKLLPEGAAALP
                     PDFADGLGSSPIVNAHVVFDRPVTDQAFFAVVDSPLQWVFDRTASSGLSRGQYLAISLS
                     AAVEEIDLPVRVLRDRLLPALREVLPAARQAEVLDFFVTRERHATFAPAPGSAGLRPPA
                     RTRAPGLVLAGAWTATGWPATMEGAVRSGEAAAQAVLGTSAEVPGRSEGIPA"
     gene            13103..14113
                     /locus_tag="IE290_RS36120"
                     /old_locus_tag="GCM10017786_73240"
     CDS             13103..14113
                     /EC_number="2.5.1.-"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017983010.1"
                     /locus_tag="IE290_RS36120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_73240"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_191249230.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 5.9e-62, bitscore:
                     202.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAVLDSLQQGRQAVLPAMRAAIDRLDPASRAIAYYHLGWTDLDG
                     NPTSGGGKAVRPALALLSAEAAGAPPATGLPGAVAVELVHNFSLLHDDLMDGDTERRHR
                     PTVWAVRGAASAILTGDAMLALANEVLLDSDGPGAVAAARLLSEAVGELIRGQVLDVAF
                     EQRDDVTLDECLDMAGGKTGALLSASAAIGAVLACAPARTVSALAEFGADLGLAFQLVD
                     DVLGIWGEPSVTGKPVHSDLRARKKSLPVTYAITHGGAPGRELAAWLTDGDVADDDAVR
                     RAADLVDLAGGRAWALEEAHRRMAAGQRKLEDAEVPGRVREELLALARFIVTREA"
     gene            14114..16012
                     /gene="shc"
                     /locus_tag="IE290_RS36125"
                     /old_locus_tag="GCM10017786_73250"
     CDS             14114..16012
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020421276.1"
                     /locus_tag="IE290_RS36125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_73250"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_191249231.1"
                     /sec_met_domain="T2TS (E-value: 3.3e-150, bitscore: 494.7,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQTADPATRSGAGAAEALDRAVAHLKGLQRDGGWWKGELQTNVT
                     MDAEDLLMREFLGIRTARETEEAARWIRSQQRADGTWATFYGGPGDLSTTLEAWVALRL
                     AGDSPDEPHMRKAAEFVRAGGGVEASRVFTRIWLALFGLWSWDDLPNMPPELVLLPSWV
                     PLNVYDWGCWARQTVVPLTVVSTLRPVRPLPFGIDELRTGVKRGGLVAPWTWSGAFHYL
                     DKALHAYAKVAVKPVREFAMRQAAEWILARQEADGGWGGIQPPWVYSLLALHLLGYSLD
                     HPAMRAGLAGLEGFLIREETPEGTVRRLEACQSPVWDTALAITALLDAGAPGDDPHVLK
                     AVDWMLGEEITVRGDWAVRRPDLDPGGWAFEFANDLYPDTDDTAEVVLGLRRVSHPDSE
                     RLDRALDRAVKWVTGMQSRDGGWGAFDADNTQELTTKLPFCDFGAVIDPPSADVTAHVV
                     EMLAKEGKAGSRECRRGVKWLLDHQEADGSWFGRWGANYVYGTGAVVPALVEAGVPSSA
                     TAIRRAVTWLAEHQNADGGWGEDLRSYRDPSWAGRGESTASQTAWALLALLAAGERDSE
                     VTARGVRWLAETQRPDGTWDEPQFTGTGFPGDFYINYHLYRLVFPVTALGRYLERS"
     gene            16009..17484
                     /gene="ispH"
                     /locus_tag="IE290_RS36130"
                     /old_locus_tag="GCM10017786_73260"
     CDS             16009..17484
                     /EC_number="1.17.7.4"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051745 - 4-hydroxy-3-methylbut-2-enyl
                     diphosphate reductase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /GO_process="GO:0050992 - dimethylallyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="ispH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017983008.1"
                     /locus_tag="IE290_RS36130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_73260"
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="WP_191249232.1"
                     /transl_table=11
                     /translation="MTGVVVAPMRVEASALRMPGLVVLRGGMGPRRAAESAQRLAAAGR
                     PVLVAGVGGALVPDVRPGDLVVATEIDGPDGRVPLPSAPMLAAALRRLGLTVHLGPIAS
                     SPSVVDGAERARYARSGALAVDMESAEFAGLPGPVAVVRAIVDTPDQPLWRPGTVLRGL
                     SGLRSLRAAVPALREWCEAAGEGELLLASPRSFCAGVERAIEIVERALERYGAPVYVRR
                     QVVHNAHVVRRLEALGAVFVQEVEEVPRGATTVLAAHGVAPAVRAAAQARDLRVIDATC
                     PLVMKVHSEVKRYTGRGDTVFLIGHADHEEVEGTVGEAPERIVVVEDAEAAAHVRAPDG
                     GRVAYAMQTTLAVDEAEEIASVLRKRFPSIEGPRRDDICYATTNRQRAVTTVAEEADLV
                     LVVGSANSSNSLRLVEVARRRGTRARLVDDVSEVDLRWLAGATRIGITAGASAPPDLVA
                     ELVRCLQGLGRTRVTETVRADEDVVFTLPREVS"
     misc_feature    17464..17466
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17488..18492
                     /gene="hpnH"
                     /locus_tag="IE290_RS36135"
                     /old_locus_tag="GCM10017786_73270"
     CDS             17488..18492
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017983007.1"
                     /locus_tag="IE290_RS36135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_73270"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_191249233.1"
                     /sec_met_domain="PF04055 (E-value: 2.9e-18, bitscore: 60.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 9.8e-09, bitscore: 28.5,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQSIRLGAFLAKQKLLRKEKYAILVELEPLFACNLKCGGC
                     GKIQQPAHLLKQRMPVQQAVGAVEESGAPMVSIAGGEPLMHPQIHEITRILLERNKIVF
                     LCTNALLLPKHIHKFKPHRNFTWMVHIDGLEEKHDASVRKEGGFQAAVEAIQLAKSQGF
                     KVMTNTTFFNTDTPQDVIDVLDYLNDVVKVDNMQLSPGYAYEKAPDQEHFLGVQQTREL
                     FAKAFADGRRKKWRLNHSPVFLDFIEGKRDLECTPWGIPSYSLLGWQRPCYLLDDGYAK
                     TWRELIEETEWDKFGRGKDPRCANCMAHCGYEPTAVIATTSSLKETIRAAVSV"
     misc_feature    17500..17502
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18528..18929)
                     /locus_tag="IE290_RS36140"
                     /old_locus_tag="GCM10017786_73280"
     CDS             complement(18528..18929)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020421273.1"
                     /locus_tag="IE290_RS36140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_73280"
                     /product="hypothetical protein"
                     /protein_id="WP_191249234.1"
                     /transl_table=11
                     /translation="MDLVERYVALWKETGADARRKAIELLWHEDGVHLLQPPREMRDRA
                     IALGFGDAVLAARGYAAIEERVRRGYEDFLAPAGVTLRAGGNTDRLGDTVKFNWELVDG
                     SGQLRSTGLEVLTLAADGRIAVDHQFFES"
     misc_feature    18905..18919
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.96"
                     /tool="antismash"
     gene            complement(18980..19627)
                     /locus_tag="IE290_RS36145"
                     /old_locus_tag="GCM10017786_73290"
     CDS             complement(18980..19627)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020421272.1"
                     /locus_tag="IE290_RS36145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_73290"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_191249235.1"
                     /transl_table=11
                     /translation="MGDRAAKTELYDALAETAKALASGRRAELVDVLVQGERPVDELAA
                     EIGQSVANTSQHLRRLLRSGLVRTRREGTRVFYSLAGAAVARLWLAMRAAAEEHVEGLT
                     RLAEDYVGDRSGLDTITRDELDRRLRDGDVVVLDVRPAPEYAAGHIPGAVSIPITELRA
                     RLTEVPDGAQVVAYCRGPYCVYADDAVRLLTAAGHRAARLEDGYPEWAAARA"
     misc_feature    complement(19678..19691)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.97"
                     /tool="antismash"
     gene            19967..21322
                     /locus_tag="IE290_RS36150"
                     /old_locus_tag="GCM10017786_73310"
     CDS             19967..21322
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163: rhodanese domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010314231.1"
                     /locus_tag="IE290_RS36150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_73310"
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="WP_191249236.1"
                     /transl_table=11
                     /translation="MSTVDVLPLVDEGLGNSAYLVDLGDGRALVVDVSLDLRAARRAAR
                     RRGLRLAFAADTHLHADFVSGARQLAVTDGARVLASAAGQREFTHDGLRDGDETDLGGL
                     RLRALFTPGHTHEHLSFLLLDGDTPVGVFTGGSLIVGAAARTDLVDPDRTDELARRQYA
                     SLRRLATLPDEVAVWPTHGAGSFCSAPPGARRTSTIGTEKATNTLLRAENEDAFVTALL
                     DSLGSFPSYFRELADTNRRGVVLPGDPTLPGLDVDRVRGLCGDGAVVVDARPAADFAAG
                     HLPGALSNPLRPAFASWLGWLVPAGRPIVVVRGADQDPAEIAWQAVKIGRTDLAGELAG
                     GLDAWTAAGQPVRRTPVVTPAGIGRRPVLDVRQDGEFAAGHLPGARHRELGRLDPRELP
                     REPLVVMCGHGERAMSAASLLEQAGHHEVAVLLASGPADWARATGNALVTGA"
     gene            21319..22533
                     /locus_tag="IE290_RS36155"
                     /old_locus_tag="GCM10017786_73320"
     CDS             21319..22533
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1137: Major
                     facilitator superfamily MFS 1"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019811822.1"
                     /locus_tag="IE290_RS36155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_73320"
                     /product="MFS transporter"
                     /protein_id="WP_229874917.1"
                     /transl_table=11
                     /translation="MTVRLGLRANLAQFTLLVAVNALVGGVLGQERTVLPLLAGPVFGL
                     SGYTVLLTYVLAFGLTKAAANYLAGTLSDRHGRKPVLLAGWLIAVPVPATLALAPDWGW
                     IVAANVLLGLSQGLTWSTTVIMKIDLAGPRRRGLAMGLNEAAGYGALALTAAATGYLAA
                     HFGLRPAPFLLGAAYVALGLGLTAAFVRETRDHARSESHPATAVLSGWAVFARTSVRDR
                     AMSAASQAGLVNNLNDGLAMGLFPVLFVTTGLSVAGAGVLAALYPAVWGAGQLVTGPLS
                     DRWGRKHLITAGMLVQAAALGLTALGTGFAVWAVAMVLLGAGTAMVYPTLLAVVGDVAH
                     PAWRARAVGVYRLWRDSGFAAGAVVSGLAADLWGLRAAVAVVAALTAASGIAVAIRLPE
                     TLRRS"
     gene            complement(22535..23506)
                     /locus_tag="IE290_RS36160"
                     /old_locus_tag="GCM10017786_73330"
     CDS             complement(22535..23506)
                     /NRPS_PKS="Domain: PKS_ER (23-321). E-value: 7.3e-51.
                     Score: 165.1. Matches aSDomain:
                     nrpspksdomains_IE290_RS36160_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005437574.1"
                     /locus_tag="IE290_RS36160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_73330"
                     /product="quinone oxidoreductase"
                     /protein_id="WP_191249237.1"
                     /sec_met_domain="ADH_N (E-value: 2.1e-12, bitscore: 40.5,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2e-28, bitscore:
                     92.6, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTAVQIRRTGGPEVLEAGDVEIGDPGPGELLVDVAAAGVNYIDT
                     YQRGGIYKIDLPATLGMEGAGTVAAVGEGVSGFAVGDRVAWQGVLGGYAQRALIPASAA
                     VPVPEGVSAETAAATMLQGITAHYLVRSTYEVQDGDTILLHAAAGGVGLLLTQLAKARG
                     ARVIGTVSTEEKAALAREAGVDEVIRYDQVDFAEEVRRLTGGEGVAAVYDGVGKSTFDG
                     SLASVRVRGFLVLFGAASGPVPPFDPQRLNAAGSVYLTRPTSAHYVRTREELEWRTGEL
                     FEAVASGALKVRVGAKYPLAEAAKAHEDLQGRRTTGKVLLIP"
     aSDomain        complement(22544..23437)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE290_RS36160_PKS_ER.1"
                     /evalue="7.30E-51"
                     /label="IE290_RS36160_PKS_ER.1"
                     /locus_tag="IE290_RS36160"
                     /protein_end="321"
                     /protein_start="23"
                     /score="165.1"
                     /tool="antismash"
                     /translation="GDPGPGELLVDVAAAGVNYIDTYQRGGIYKIDLPATLGMEGAGTV
                     AAVGEGVSGFAVGDRVAWQGVLGGYAQRALIPASAAVPVPEGVSAETAAATMLQGITAH
                     YLVRSTYEVQDGDTILLHAAAGGVGLLLTQLAKARGARVIGTVSTEEKAALAREAGVDE
                     VIRYDQVDFAEEVRRLTGGEGVAAVYDGVGKSTFDGSLASVRVRGFLVLFGAASGPVPP
                     FDPQRLNAAGSVYLTRPTSAHYVRTREELEWRTGELFEAVASGALKVRVGAKYPLAEAA
                     KAHEDLQGRRTTGKVLL"
     CDS_motif       complement(22973..23020)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE290_RS36160_0003"
                     /evalue="1.00E-03"
                     /label="PKSI-ER_m6"
                     /locus_tag="IE290_RS36160"
                     /protein_end="178"
                     /protein_start="162"
                     /score="12.0"
                     /tool="antismash"
                     /translation="GARVIGTVSTEEKAAL"
     CDS_motif       complement(23030..23092)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE290_RS36160_0002"
                     /evalue="4.90E-06"
                     /label="PKSI-ER_m5"
                     /locus_tag="IE290_RS36160"
                     /protein_end="159"
                     /protein_start="138"
                     /score="19.1"
                     /tool="antismash"
                     /translation="GDTILLHAAAGGVGLLLTQLA"
     CDS_motif       complement(23291..23329)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE290_RS36160_0001"
                     /evalue="2.60E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="IE290_RS36160"
                     /protein_end="72"
                     /protein_start="59"
                     /score="10.8"
                     /tool="antismash"
                     /translation="LGMEGAGTVAAVG"
     gene            23585..23890
                     /locus_tag="IE290_RS36165"
                     /old_locus_tag="GCM10017786_73340"
     CDS             23585..23890
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020421267.1"
                     /locus_tag="IE290_RS36165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_73340"
                     /product="hypothetical protein"
                     /protein_id="WP_191249238.1"
                     /transl_table=11
                     /translation="MAEETEAPAPTAKQLTTARRFVAEHGKPAKAVVENIGRAGARVVL
                     VGHDGALGDIVVPAVETGQKLVEAVEDLEPAEWDAETTNSTKIGPGHRRRMAGHAL"
     gene            complement(23894..24808)
                     /locus_tag="IE290_RS36170"
                     /old_locus_tag="GCM10017786_73350"
     CDS             complement(23894..24808)
                     /EC_number="1.14.19.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) delta9_cd03505"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020421266.1"
                     /locus_tag="IE290_RS36170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_73350"
                     /product="acyl-CoA desaturase"
                     /protein_id="WP_191249239.1"
                     /sec_met_domain="delta9_cd03505 (E-value: 2.5e-109,
                     bitscore: 360.5, seeds: 90, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKPLISHRRSSGQMIVLKAFLLIPFLALITAVPLAWGWGLTWLD
                     LGLAVFFYVVATLGVTVGYHRYFTHGAFKTGRPLRVAMAIAGSMAVQGSVIFWVASHRR
                     HHAFADREGDPHSPWLFGTSPAALLRGFWHAHMGWMFQREVTNYERFAPDLLADDDLRV
                     VNRLFWLWIVLSLGLPTLLGGLLSWSWWGAVTAFFWAGLVRIAFLHHVTWSVNSICHMI
                     GDRPFASRDKAANFWPLAILSMGESWHNSHHADPTCARHGVLRGQLDVSARVIWIFEKL
                     GWARDVRWPRAERLAAKRLEPAS"
     gene            complement(24920..25897)
                     /locus_tag="IE290_RS36175"
                     /old_locus_tag="GCM10017786_73360"
     CDS             complement(24920..25897)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020421265.1"
                     /locus_tag="IE290_RS36175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_73360"
                     /product="heme A synthase"
                     /protein_id="WP_191249240.1"
                     /transl_table=11
                     /translation="MALKSLIARLPYPSRPVQRAIAVAAIVAQAGIGVTGSVVRVTGSG
                     LGCPTWPQCFPGSMVPVAHPEFDTLNQWIEFGNRMLTVVVVLVSALAVLAAWRVQIAHP
                     ERKRLVRLAWTMPGGVVLQAVVGGITVLAKLEWWTVAIHFLASTPLVWLAVLLLRAFNE
                     GDRPARWLVPPLAKKLLVTLVVALWAILIAGTTVTGAGPHGGDPETHRLDAPIEVLAQV
                     HGGLLVLYLLVLAVFGLVLMRGGTPAVVWRRYSIVWLVALAQGVLGSVQYALGIPEALV
                     SLHVLGSALVIVATAALWCGCRDRGPVTSDGPAPREPELTAARG"
ORIGIN
        1 gttctacctg gccaccgccg cctcgccgga gggcgtgcgg cggcgcaggc acatccgcac
       61 gctcagccgc aaggtcgtcg gcctcgacga cgagatcctg gacctccgcg cggtcgacgg
      121 gcagcaggcc gacctgggac tggccgggga ggccgccctg ctggccgcgc tggagcgcaa
      181 gcgcacgggt gagatgggcg acatcgtcgc caccatccag gccgagcagg acgacatcat
      241 ccgcgacgag ctgggcggcg tggtcgtcgt gcagggcggg ccgggcaccg gcaagaccgc
      301 cgtggccctg caccgggccg cctacctcct ctacacctac cgccagcagc tcgcctcgcg
      361 cggtgtgctc gtggtcggcc cgaacagcac gttcctgcgc tacatcggcc aggtcctgcc
      421 ctcgctcggc gagaccggcg tgctgctgtc cacgatcggg cagctgttcc ccggtatccg
      481 ggcccgtggc gcggacagcc gggaggccgc cgaggtcaag ggccgcccgg tcatggtcga
      541 cgtgctcacc cgggccgtcg ccgaccgcca gcgggtgccg gaggagaagt tcgaggtcgc
      601 cttcgacgac gacgtgctgg tgctggaccg ggacgtggtg gaacgagccc gcgacaaggc
      661 ccggcgcacc cgccgcccgc acaacctcgc gcggcgggtg ttcgtcgacg cgatgctcga
      721 cgcgctgacc gagcgggcca cggtccgcat ggaggtcgac ctgttcgccg gcgtgccgga
      781 catcccgctc gccgcgggcg aggacgccga cgcgccggtg ctggacgcgg gcgaccgggt
      841 ggagatccgc aaggaactgt ccgagtccga caccgtcgcg gccgcgctgg acgaactgtg
      901 gccgaagctc accccccagc ggctgttgcg tgacctgttc gccgacgccg accggctgct
      961 cagcgcgtcc gaggggctgc tgtccgacga tgaccgcgcg gcgctcaagc gcccggcgcg
     1021 gtcgccgtgg acgcccggcg acgtgccgct gctcgacgag ctggccgagc tgctcggcga
     1081 ggacgacgcg gccgagcggg aggcccgcga gcggcgggag cgcgaggagc gcgcctacgc
     1141 cgagggtgtg ctcgacatca tggaccagga cgaggagctc ctggacgagg accagatcaa
     1201 catcgccgac atcctggacg ccgagctgtt cgccgagcgg caggagcgca gcagccacct
     1261 gaccgccgcg cagcgcgccg cccgcgaccg cacctggacg ttcgggcacg tcatcgtcga
     1321 cgaggcgcag gagctgtcgg cgatggactg gcggctgctc atgcggcgct gcccgagccg
     1381 gtcgatgacc gtggtcggcg acgtcgcgca gaccggcgcg cccggcggcg cgtcgtcctg
     1441 gcgggacatg ctcgaacgct acgtcggcga ccggtggcgc ctgcgcgagc tgacggtcaa
     1501 ctaccgcacg ccggtggaga tcatggacct cgccgcggag gcactgcgcg aggtcgaccc
     1561 ggacctgcgg gtgccggcgt cggtgcggga gaccggggtg cggccgtggc gcgcgccgct
     1621 cggctcgcgg cccctgacgt ccattgtgga cgaggaggtg gcggccgcgg acggcggcac
     1681 cgtggcggtg ctggtccccg cgtcccggct cggcgcggtc cggtccgaac tggacggtca
     1741 cgcggaggcg gtgtcggtgc tgaccgtggc cgaggccaag ggattggaat tcgacggggt
     1801 cgtggtgctg gcgccggagg agatcgtggc ggagtcgccg cgcgggtgga acgacctgta
     1861 cgtggcgtac acgcgggcca cccagcgcct cgggattctt tacacggagc gctaacccgg
     1921 gcaaaccgac tggtcagcgc ccggttaagg tgtcgccatg cgtaacgctg gcaagatcgt
     1981 gctcgcggcg gcagccgccc tcgctctcgg ggcctgcgcg cccgaccagg acccgtcgtc
     2041 cttcccgccc ggtggcggcc cgacctaccc ggcgccggag ccggcggggg cgtccgccag
     2101 cgcctcggcg gggcacggga cgggcagcgc cgcgcacgag tgcaccgcgg acgacatcac
     2161 cgtgaccggc gacttcggcg ccaagcccac gatcaccatc ccggacgact gcggtgcgcc
     2221 gacgaagctg ctgaccaagg acctgaagcc gggcaccggc gccaccgcgc acgccggcag
     2281 cacgctgcag atggactacg acctggtcac ctggtcggac aaggtggacc agcagaactc
     2341 cttcggggcg gcgccgttct cgttcgcgct cggcgagggc accgccatcc cgggctggga
     2401 ccagggcctg gagggcatca agcagggtgg ccgccgtctg ctggtcatcc cgccggacct
     2461 gggctacggc gcgcgcggca acggcccgat caagccgaac gagacgctcg tcttcgtggt
     2521 cgacgcggtg caggtcacgg gctgacgtcg cggtgacggc cgcgggaagc tgggccggcg
     2581 gcagccggcc tcgctcctcg cggcccgcgg gctcggccgg cggaagccgg ccttggccgc
     2641 acggcccacg gggcgggcca gtggtggccg ggttgccggg gcctcgctcc cgcggcccag
     2701 cgcgggcggg ggccgcagga aggtggccgt ccgccaggct cgctcgggaa gcccgcgtgg
     2761 gggccggtag cagccggctt cgctcctcgc ggcccgcgca gttggccgcg gcccggctgg
     2821 agggtgggcg ccgcccgtac gtcgcccgga tcggaggctg accatggacg tccgtggtgc
     2881 ggtcgcggtg gtcaccggtg cctcgtcggg catcggggcg gccacggcgc tccggctgca
     2941 cgaggctggt gctcgcctcg tgctgcatgg gcgggacggc gaccggctgg cggcgctcgc
     3001 cgagcgcacc ggcggggtcg ccgtccgtgc cgacttcgcc gagcccggcg ccgtcgaggc
     3061 cgcggccgcg gagatcaccc gggccggccg catcgacgtg ctcgtcaaca acgccggcct
     3121 cggctacgcc ggaccggtgt ccggcatgtc cggcgccgac gtccggcgat tgctgtccgt
     3181 gaacctcgcc gcacccgtcg aactgacccg cgccctgctg cccgacctcc tcgaccggcc
     3241 ccgagcggcc gtggtcttcg tcacatccat cgccggccgg gcgggcgtcg cgggggagtc
     3301 ggtctactcc gcgaccaagg cgggcgtgga cgtgttcgcc gagagcctgc ggctggaact
     3361 ggccggtacc ggggtgcggg tcggggtcgt cgtccccggt gtggtggaca ccgagttctt
     3421 cgcccgccgc ggccgtccct accagcggcg cagcccccgg ccggtgcccg cgggcaaggt
     3481 cgccgacgcg gtgctcgagg cgatcacggc cgaacgggcc gagcagtacg tcccccgctg
     3541 gctcagactg ccaattgcgg tgcgcgcgac cgctccctcg gtgtaccgtg cactatctgc
     3601 ccggttcggg ggttcgagct gagttcccgg aatctttccg ccactggaag cgctgaaaag
     3661 tgacgtgtta gtcccggtat tcctcggatt cgccgcggcg ttcctgttcg cggcgtcagc
     3721 cgcgctgcag cgacgcgcgg tgatcgaggt tgccgacacc gaggccggcg ggcgcgccgc
     3781 gcggcaccgc gtccccgtac tgtggctgat ccgcaagctg ttgcgcaaga gggtgtggct
     3841 cgcgggatgg gccacgaacc tgttgggctt tttcagccag gccgccgcgc tgcacttcgg
     3901 gtcgatcgcg ctcgtccagc cgctgctggt caccgaactg ctcttcgcgc tgccgatggc
     3961 ctcggccgcg atcaagcgct ggccgccgct gcgggactgg ctggccgggc tcgccatcac
     4021 cgggggcgtg gtggtgttcc tgacggtcga gggcaccgcg ccgctgggcg ggtcgccgga
     4081 ccagggccgc ctgctgatcg ccgtgctcat cgccgcggcc accgtcgtca ccctcgtgca
     4141 ggtcgcccag aagcgcggcc cgctcctgca cagcgcgctc atcgccaccg ccgcgggcat
     4201 ctgctacgcg atcagcgcgg ccatgatgaa ggtgaccacc gacctgctgt tgaacgaggg
     4261 tgtcgctcac accgcgctca cctggccggg gtacgtcctg gccctgtcca ccttgtccgg
     4321 gctgcttctc gggcagcagg cgtacgggtc gggttcgctg tccgcggcga tcgccgtgat
     4381 gtccatcgtc aaccccgcgg ccagctactt cctggggcta ctggcgttca acgcgaccct
     4441 ggtcaccgag ccgggaccgc tcgcggcgac ggcgggcgcg gccgtgctgc tgatcgtcgg
     4501 cgtgttcggg ctggcgcact cgccgagcgt ccaggcggag accagccgat ccgcccaacg
     4561 cggggtttat cccggaagtg gtaaattctc cggaaccgtc cccgcccgat cttcggactc
     4621 cttcgctcag gaataattca ggtatccggc gtaggtttcg ggcccggcgg gcggtggaac
     4681 ctacagagcc tgtcagtgag tgcgctgccc ccgcgcaccc aggcagaccc ttggaggctg
     4741 gaacccgtgc accaccgagc gtcctccggc gagcgccatt tggtgatcga aataccgcat
     4801 ttgcggaaaa cgatcaagga tgcggcgatt ctgctgctgg aaaccgtcgt catcccgtcg
     4861 gtgctcctgg ctttgctgct gaatttcgtc ggtctggtac ccgcgttgtg cgcggtgctc
     4921 ggctgggcgg ccgtcgtcat cggcgcccgg cgcctgatga agcgcgacat gccccgcacg
     4981 ctgctgctgt gcacggcgat gctggtcgga cgggcggcgg tcgcgctggt gacgtcgagc
     5041 gcggtcgtgt acgtgctgca accggccgtg ggctcggtgc tgatgttcct gatcttcgtc
     5101 ggcagcgcga tgatcgggcg ccccatcacg gcgcgcctgg ccaaggactt cgtgcggctg
     5161 cccgcggagc tgttcaagca ccgcacggtg aaccgcgtgt tcatcgaggt ggccctgctg
     5221 tggggcggct cgcggctcat cgacgccgcg atgaccatcg ggttcctgca ctggggggtc
     5281 ggggccggcc tgatgtcgcg cggcatcctc agcgggctgc tgaccgcgct gaccgtcgcg
     5341 gcctgcgtgg gccacggctg gcgcaaactc cgccgcgacg gcgtgacgct ccgcctggcc
     5401 ggccgccaca ccccggcacc cgccgccgcc tgacccgcgc cgcgcgcgaa ctccgcgcgc
     5461 tcaccggggt ccgctcacgc cgccgcgccc gggccgggca gcaggtccac gttcccggcg
     5521 tgcagggcct cgccgcagtg gtcgcacctc aggccggccc cgctgacctc cccgcacgcg
     5581 tggtgccggt acaccaccgg cggccccgcc tcgcccgcca gccaccggtc gccccagttg
     5641 gccatcacca tcagcacctc gaccagctcg gcgcccttct gcgtcagcac gtactcgtag
     5701 cgcggccgcc ggtcgtaggg ccgccgctcc agcaccccgc gctccaccag gtggttcagc
     5761 cgctcggtca gcaccttccg ggatatcccc agatcggcct ggatctgctc gaaccggctc
     5821 agcccggccc acacgtcccg cagcaccagg ggcgaccacg gctccccgat gacgtccagc
     5881 gtgcgcgcga tcgagcacgc catccccccg aagttcgtcc gctgcatgga cccgagtcta
     5941 gcaatcgggg ttccctgaag gaactcacac tgctacggtc ggagtctctt gaaggaactc
     6001 cgaagggaac ccgagatgag caaggtcatc gccgcgcacg cggtctccgt cgacggcttc
     6061 atcaccggcc gcgaccccca accgggccac ggcctcggcg acggcggaat gctgttcgac
     6121 tggtacttcg gcggcgacac cccgagcggc gtgttcgacg gcttctggct gagcgagccc
     6181 agcgcccgcg tgttcgacgc cctcgccggc cgggtgggcg ccatcgtcgc cgggcgcacc
     6241 acctacgagg actccgagcg cttcggcggc ggcagcccgc acccgaaggc ccggttggtc
     6301 gtcctgagcc accggcccgc gcagaccagc gaccggcaga tcctcgccgc cggcatcgag
     6361 gacgcgatcg cccgcgcgcg ggaagccgcc ggcgacctgg acgtcggcct catgggtggc
     6421 ggcgtcgtca ccgcggcgct ggcggccggc ctggtcgacg agatcgtcct gcaccaggtc
     6481 ccggtcctgc tcggcgccgg acggccctac ttccgggaac tgcccgcgca cgtgcggctc
     6541 cgcctcgtcg aagccgttcc agcgccgggc gtcacccacc tccactacgc ggtcgagcgg
     6601 tgattcgagc gagcgcaccc gccacgaagc gtggtatatg acggtgtgct caccgtaggt
     6661 tccacctcac ggtccccggt ggtcgcggac gcccgcgcgg cggccgtccc gcgtcccagc
     6721 tggtggggtg aactgctgct cgggctcgcc ctgttcgggg tgtacctgct ggtcgaggcg
     6781 ttcccgctgc ccggccgcga gccccgggcg cacgccaacg gtgaggcgct gctggcgttc
     6841 gaacgctgga tgcacctgga cttcgagctg ccggtcaacc tgtggctcgc cgagcagggc
     6901 tggatccgcg tcttcgccaa ctatgagtac gcgatcacct acatcgccag cgcgatcatc
     6961 ctgctgatct gggtgcacgc ccgccacccg gtctactacc ggtcggtgcg caacagcttc
     7021 gtctggctca acctgttcgc cctggcctgc ttctggctct tcccggtcgc gccgccgcgg
     7081 atgctcgagg gcgccgggtt catcgacacc gtccggctcg ggcacacgtt cctgtcctgg
     7141 ggctcaccgg cgttgcaggg tgccaaccag ctcgccgcca tgccgtcgtt gcacgtcggg
     7201 tgggcgctgt gggtgtccgt cgtcctcgcg cgcatccgcg gcggctggct cgtgcagatc
     7261 gtcagcgccg tccacgtcgc catcacgttc gcggtgatca tcgccaccgg caaccactac
     7321 tggatcgacg cggccgccgc cgtggtgttc atcgccgcgg cgacctggat cgcgcgcctc
     7381 gcgcggccgg tcgaccgggt gtccgcgtcc gacacgttct tcctgcacgt cgagaccccg
     7441 gcctacccgc agcacgtcgg cgggctgatc atgctcgaca cgtcggcgaa cccgtccggt
     7501 ccgacccgcg agtgggtgca gaacgccatc cgcgacaagc tgcccgcgat gccccgctac
     7561 gcgcagcgcc tgtcggacta ctcgccctgg cggcgccagc actgggtgcc gcacccggac
     7621 atcgactggg actggcacgt ccccgatttc gacctgaccc gcccggacgg cacgcccggc
     7681 gggatggggg agctgcaccg gctggtcgcc cggttccaga gcgagccgct gccccgggac
     7741 cgcccgctgt ggcggttcgc cgtggtgcgc ggcgtcgagg agaacaccgc ggccgtgatc
     7801 tcgctggtgc accacgcggt cgcggacggc atcggcacga tcagcctgat gctcgagctg
     7861 ttcgactcgc ccagcctgct cgaggggatc aacgagacca ggcagcccaa cgccctgcag
     7921 aaggccgccg cgggggccgt cggcctggcg cagctggcca ccgacgggcg gcccaaggcg
     7981 caactgccgt ccggcgaccc gccggatcgc cgctacgcga ccctgcagat cccgctcgac
     8041 gacgtccgcg agctggcgcg caagcacggc gtccgggtga ccgacctgct cctgggcggg
     8101 gtcgccgggg cgctgcggcg ggtcgcggtc gcgccgttgc cggagtcgat gctcacctcg
     8161 gtcacgctga tggccgccga accgcggccc ggcgcggagg gcaacgtcac cgccgcggtg
     8221 atggtcgaca tcccgctggg ggacatgccc gaagccgaac gcctgaagcg gatcgcgcgg
     8281 gccaccaagc ggttgcgcac cggcacgcgg gtcgtcgcgt cccggttcgt gcagcacacc
     8341 ctggccggcc tgatgccacc gttcttccac tcctggttcg cccggactgt ctacaatgaa
     8401 cggttcttca acggcaccgt gtccaacatg cccggtgcgg cctggcaggt gagcttccgg
     8461 gacttcccgc tgcgcaccgc gttcgccatc atcccgctcg cgccgggaac accgttcacc
     8521 gtcggcgtgc tggggtggta cgggtcgttc tcgatgagcg ccaccgtgga cgcggcgctg
     8581 gtggacagcg tggacggttt cctcgccgag ttccgcgcgg tgctggcgga actggactga
     8641 cccggcctca gaggtcgccg gattccgggc cgccccaggc gagggcgagc gtgaggcggc
     8701 ggcggttgtc cggatcgtcc aggctctcgc cgaacagctc acgcagctgg gtcatccggt
     8761 agcgcaccgt ctgcgggtgg atgtgcagct cctccgccat cgcccggcgg tcgcccaggt
     8821 gccgcagcca gcacgcgagc gtctcgcaca accgcttgcg cgtcaccggc ccgaggtgcg
     8881 ccagcggggc caggcactgg tgccgcatcg cgtcgaacag cttcgcgtcg cggtgcacga
     8941 tgatcgagtc caggtgctcg tccacgaaca ccggatcgtc ctccagcacg tgcgtgcggc
     9001 gcagctgcgc ggccagctcg gcaacgtgca tgctggccgg caggtgctcc agcggcacgg
     9061 cgtgcccgac caccgcgccc gccccgcgca acgccgacgc cagccgctgg cgccgctgcg
     9121 gcccgtccgg atcgggcacg atggcgcaga ccagccgctg ccgccggacg tgcagggacg
     9181 agttccccag ccgccccagc agcgcgctgc cgaccgggtt gtccggctcc accagaacca
     9241 ccgccgcctg ccggggcagc ggccagtcca cccgggccgc cgcggcgcgg atcgcggcgg
     9301 aatcggaccg gtcggacagc agcatgtcgg cgagctcgtc gcgcagccgt tcccgcatgg
     9361 ccgccgactc ggactgctcc agcacgtagc cgcgggccga cgccgaggac agctggtcca
     9421 cgaagatgaa caccgcttcg gccagcgagg cgaacatgtc ggaggggaca ccgacctcga
     9481 gcgcgacctc ggcgacgtgg tgccacgcca cccgcgcgcc gatctggtaa gccgacagca
     9541 ggctcgtcag gtcgcggccc tgctgccact gcgcgcgccc gatctcctcg aacagcggct
     9601 gctcgccgaa ccggtcaccg gcctggtcgg cgatgccgga cagttccgcg atgtcccatt
     9661 tggccatccg cagcagccgc tgcaggaaca tggtggcgga gaccaggacc tcgtcccgct
     9721 cagtgacgat gaactcggcg tagtcgggcc agtgctcgtt cagcagccgc gccacgtcgt
     9781 ccagcatgcg cggcaaccgc ttcgaggtcg ccgccgcgag ttcggccagc gtgccctcgc
     9841 tggtctccgt tcgtctgccc gccatgtcgt ggacccccac tcgctgcccg cgtgccgtcc
     9901 atcgtccggg tcaatactgt cagctcgtga caaccgtggc ttcttcattt ttgtttccgg
     9961 tgcgaagaat tcgccgcggc cacggagtga ttatgaggcg atggctcccg cacccccagg
    10021 tcccggcacg gtcggcgacc gcgcgctgcg cgaaaaggaa cacgccgaga actttcccgt
    10081 agcgctgcgg atacttcccc gtgacctgcg ggcggacctg gtcgcggtgt acgacgtcgc
    10141 gcgcgtcatc gacgatctgg gtgacgagtc agcagtccaa gatcgcacac ccgggttatt
    10201 gcgattccag cgcgatctgg aacgcacctt tcggggggag caaccacacg aacgggtatt
    10261 acgtgatctt cttcccgcga ttcggcgccg ggaactggaa ctcgacccgt tcaatcgcct
    10321 ggtgcgggcg aacctccagg accagcgtgt cgccgcgtac gccacccagg ccgagctgga
    10381 ggactactgc gtgctctccg ccgatccggt cggccggatc gtgctccgcg tcttcggggt
    10441 gcgcgacccc gtcgcggagc ggctctcgga ccgggtgtgc accgcgctgc agctgatcga
    10501 gcactgccag gacgtcgccg aggaccgccg caacgggcgg gtctacctgc cgcaggccga
    10561 cctcgccgcg ttcggggcca ccgaggcgga cctggacgcg ccgaccacga gccgcccggt
    10621 gcgcctgacc gtggccgcgc agaccgcccg cgcgctggac ctgctcaccg agggtgcggc
    10681 cctgctggac cgcctgcacg gctgggcgcg cctggccgtc gccgggtaca tcgctggggg
    10741 actggccacc ctcgacgcgc tgcgccgggc ccgctgggac gtcctggccg gtaccccgcg
    10801 cccccgcaag accgacgtcc tggcgcacct gatcgccctg ctggtgcgcc cggccgccca
    10861 tgtccgccgg atccgggaag gtggtcggct ctcatgacgg cacccacgat cgagcaggcc
    10921 tacgccacct gcgaggacat caccaggacg gaggcccgca acttctactg gggcatccgg
    10981 ctgctcaccc ggcagcgccg ctcggcgctg tgcgcggtgt acgcgctggc gcggcgcgtc
    11041 gacgacatcg gcgacggcga cctgccggtg gaggagaagg ccgcgcggct ggagacggtg
    11101 cgcaaggagc tggccgcgct ggaccgcagc accgacccgg tgatggtcgc ggtcgccgac
    11161 gccgcccgcc gctacccggt gccgctggag gcgttcgagg aactgctcga cggcgtctgg
    11221 atggacatcg agggccgccg ctacggcacg ttcgacgagc tgaccgagta ctgccggtgc
    11281 gtggccgggt cgatcggacg gctgtgcctg ggcgtgttcg gccacaagcc gcacccgcgg
    11341 gccacccact acgccgacgc gctcggcatc gccctgcagc agaccaacat cctgcgcgac
    11401 atccgcgaag acctcctcaa cggccgggtc tacctgccgc aggaggacct ggacgcgttc
    11461 ggggtcgagc tgcggatcga caacggcgcc ctggccgacc cggacggcgg tctggcgaac
    11521 ctcatccggc acagcgcggc ccgcgcccgc gagtggtacg ccgacggcct gcgcctgggc
    11581 ccgctgctgg accgccgcag cggggcctgc tgcctggcga tggcgggcat ctaccggcag
    11641 ctgctggaac gcatagccga ccagccgtcc gcggtctacg accagcggct gtcgctgtcc
    11701 gggcgggaga agctgggcgt ggcggtccgc gccctgggcg ggcgggcggc atgaggcagc
    11761 gggtcgcggt cgtcggtggc ggtctcgccg ggatcaccgc ggctctgcgc tgcgccgacg
    11821 ccgggcacga ggtgacgctg ctggagtcgc gcggcctgct gggcggcctg acccactcgt
    11881 tcacccggga cggcctgcat gtcgacaacg ggcagcacgt gttcctccgc tgctgcaccg
    11941 cctacctcgg gttcctgcgg cggctcggcg tgaccgaccg cgtgcacctc cagccgcggc
    12001 tggagatccc ggtgcactcg ccgcggctgc gccgtccggt gtggctgcgc cgcaacccgc
    12061 tgcccgcgcc gctgcacctg gccgactcgg tgctgcgcta caccccgctc ggtctcgggg
    12121 accggatgcg cttcgccggt gccgcgctcg cgctgaagtc ggtcgacccc gccgcgccca
    12181 gctcggaccg gcgcaccttc ggcgaatggc tggccgcgca cgggcagagc cgcgacgcga
    12241 tcaggaagct gtgggacctg gtcggcatcg cgacgctgaa cgcccccgcc gagcaggcgt
    12301 cgctgggcct ggccgcgacc gtgttccagg tgggcctgct gaccgacgcg gacgccgcgg
    12361 acatcggctg ggccacggtc ccgctgcgca aactgcacgg cgaacccgcg ctggcccggc
    12421 tgaccgaggc cggagtgacc gtccggctca acacgaaggt gaccggactg tcccgcgcgg
    12481 acggcgtctg gcgcgtcgag gccggggagc cggtcgaggc cgaccaggtc gtgctggccg
    12541 tgccgccgcc ggccgccgcg aaattgctgc ccgaaggcgc ggccgccctg ccgccggact
    12601 tcgcggacgg cctgggcagc tcgccgatcg tcaacgccca cgtcgtgttc gaccgtcccg
    12661 tcaccgacca ggccttcttc gccgtcgtcg actcgccgct gcagtgggtg ttcgaccgca
    12721 ccgcctcgtc cggcctgtcc cgtgggcagt acctggcgat ctcgttgtcc gcggccgtgg
    12781 aggagatcga cctgccggtg cgggtgctgc gggaccgcct gctgcccgcg ctgcgcgagg
    12841 tgctgcccgc cgcgcgccag gccgaggtcc tggatttctt cgtgacccgt gagcggcacg
    12901 ccacgttcgc tcccgcgccg ggcagcgcgg gactgcgccc acccgcccgc acccgcgccc
    12961 cggggctggt cctggccgga gcgtggaccg ccaccggctg gccggcgacc atggagggcg
    13021 ccgtgcgcag cggtgaggcg gccgcccaag ccgtactcgg cacctccgcg gaggtgccgg
    13081 gccgatcgga agggataccc gcatgaccgc tgtactcgat tccctgcagc agggcaggca
    13141 ggccgtcctg cccgcgatgc gggccgcgat cgaccggctc gacccggcca gccgcgccat
    13201 cgcctactac cacctcggct ggaccgacct ggacggcaac ccgacctccg gcggcggcaa
    13261 ggccgtgcgc ccggcgctgg cgctgctgtc ggccgaggcc gccggcgcgc ccccggccac
    13321 cgggctgccc ggcgcggtcg cggtggagct ggtgcacaac ttctcgctgc tgcacgacga
    13381 cctgatggac ggcgacaccg agcggcggca ccggccgacc gtgtgggcgg tgcgcggcgc
    13441 ggccagcgcg atcctcaccg gcgacgcgat gctcgccctg gccaacgagg tcctgctgga
    13501 ctccgacggt ccgggcgcgg tcgcggcggc ccggctgctg tccgaggcgg tcggcgagct
    13561 gatccgcggc caggtcctcg acgtcgcctt cgagcaacgc gacgacgtca ccctcgacga
    13621 gtgcctggac atggccggcg gcaagaccgg cgcgctgctg tccgccagcg ccgcgatcgg
    13681 cgccgtgctc gcctgcgcgc cggcccgcac ggtcagcgcg ctcgccgagt tcggcgccga
    13741 cctgggcctg gcgttccagc tggtcgacga cgtgctcggg atctggggcg agccgtcggt
    13801 caccggcaaa ccggtgcact ccgacctgcg ggcccgcaag aagagcctgc cggtcaccta
    13861 cgcgatcacc cacggcggcg cgcccggccg ggagctggcc gcgtggctga ccgacggcga
    13921 cgtcgccgac gacgacgcgg tgcgccgcgc ggccgacctg gtcgacctgg ccggcgggcg
    13981 cgcgtgggcg ctggaggaag cccaccgccg gatggcggcg ggacagcgca agctcgagga
    14041 cgccgaggtc ccgggacggg tgcgcgagga gctgctggcc ctcgcgcggt tcatcgtgac
    14101 cagggaggcc tgaatgacgc agaccgctga tccggcgacc agatccggcg ccggtgccgc
    14161 cgaggcgctg gaccgcgccg tggcccacct caagggcctg cagcgcgacg gcggctggtg
    14221 gaagggcgag ctgcagacca acgtcaccat ggacgccgag gacctgctga tgcgggagtt
    14281 cctcggcatc cgcaccgcac gcgaaaccga ggaggccgcg cgctggatcc gttcacagca
    14341 gcgcgcggac ggcacctggg ccaccttcta cggcggcccc ggggacctgt ccaccaccct
    14401 ggaggcgtgg gtcgcgctgc ggctggccgg ggactcgccg gacgagccgc acatgcgcaa
    14461 ggcagccgag ttcgtccgcg ccggcggcgg ggtcgaagcc agccgcgtgt tcacccggat
    14521 ctggctggcg ctgttcgggc tgtggtcgtg ggacgacctg ccgaacatgc cgcccgagct
    14581 ggtgctgctg ccgtcctggg tgccgctgaa cgtctacgac tgggggtgct gggcgcgcca
    14641 gaccgtggtg ccgctgaccg tggtcagcac gctgcggccg gtccgcccgc tgccgttcgg
    14701 catcgacgag ctgcgcaccg gggtcaagcg cggcgggctg gtcgcgccgt ggacctggtc
    14761 gggcgccttc cactacctgg acaaggcgct gcacgcctac gcgaaggtcg cggtcaaacc
    14821 ggtgcgggag ttcgcgatgc ggcaggccgc ggagtggatc ctggcccgcc aggaggccga
    14881 cggcggatgg ggcggcatcc agccgccgtg ggtgtactcg ctgctcgcgc tgcacctgct
    14941 cggctactcg ctggaccacc cggcgatgcg cgcgggcctg gccggcctgg aggggttcct
    15001 gatccgcgag gagacccccg agggcaccgt gcggcggctg gaggcgtgcc agtccccggt
    15061 gtgggacacc gcgctggcga tcaccgcgct gctcgacgcg ggcgcgccgg gcgacgaccc
    15121 gcacgtgctc aaggccgtcg actggatgct cggcgaggag atcaccgtgc gcggcgactg
    15181 ggccgtgcgg cggccggacc tcgacccggg cgggtgggcg ttcgagttcg ccaacgacct
    15241 ctacccggac accgacgaca ccgccgaggt cgtgctcggc ctgcgccgcg tctcgcaccc
    15301 ggactccgaa cgcctggacc gcgcgctgga ccgggccgtg aagtgggtga ccggcatgca
    15361 gtcgcgcgac ggcggctggg gcgcgttcga cgccgacaac acccaggagc tgaccaccaa
    15421 gctgccgttc tgcgacttcg gcgccgtgat cgacccgccg tcggccgacg tcaccgcgca
    15481 cgtggtcgag atgctcgcca aggagggcaa ggcgggcagc cgcgaatgcc gccgcggggt
    15541 gaagtggctg ctggaccacc aggaggccga cgggtcgtgg ttcggccgct ggggcgcgaa
    15601 ctacgtctac ggcaccggag ccgtcgtgcc cgcgctggtc gaggccgggg tgccgtcctc
    15661 ggccaccgcc atccggcggg cggtcacgtg gctggccgag caccagaacg ccgacggcgg
    15721 ttggggcgag gacctgcggt cctaccggga cccgtcgtgg gccgggcgtg gcgagtcgac
    15781 cgcgtcgcag accgcgtggg cgctgctggc gctgctcgcg gcgggtgagc gggactccga
    15841 ggtcaccgcg cgcggcgtgc ggtggctggc cgaaacccaa cggccggacg gcacgtggga
    15901 cgagccgcag ttcaccggca ccggcttccc cggcgacttc tacatcaact accacctgta
    15961 ccggctggtg ttcccggtga ccgcgctcgg ccggtacctg gaacggtcat gaccggcgtc
    16021 gtggtcgcgc cgatgcgcgt cgaggcctcg gcactgcgga tgccgggcct ggtggtgctg
    16081 cgcggcggga tgggcccgcg ccgcgcggcg gaatcggcgc agcggctggc cgcggccggg
    16141 cggccggtcc tggtagccgg ggtcggcggg gcgctcgtgc ccgacgtccg gccgggcgac
    16201 ctcgtggtgg cgaccgagat cgacggcccg gacgggcggg tgccgctgcc gtcggcgccg
    16261 atgctcgccg cggcgctgcg acggctcggc ctgaccgtcc acctcggacc gatcgcgtcg
    16321 tcaccgtccg tcgtggacgg tgcggaacga gcccggtacg cgcgcagcgg cgcgctcgcg
    16381 gtcgacatgg agtctgcgga gttcgccggg ctgcccggcc cggtagccgt cgtccgggcc
    16441 attgtggaca cgccggacca gccgttgtgg cgtccgggca cggtgttgcg cggcctcagc
    16501 ggccttcggt cgttgcgggc ggcggtccct gcgctgcgcg agtggtgcga ggccgcgggg
    16561 gagggagaac tgctgctcgc cagcccacgg tcattctgcg ccggggtgga acgcgcgatc
    16621 gagatcgtcg agcgggcgct ggagcggtac ggcgcgccgg tctacgtgcg ccgtcaggtc
    16681 gtgcacaacg cgcacgtggt gcggcggttg gaggcgctgg gcgcggtgtt cgtgcaggag
    16741 gtcgaggagg tgccgcgcgg cgcgacgacg gtcctggccg cacacggtgt cgccccggcc
    16801 gtgcgggcgg cggcgcaggc gcgggacctg cgggtgatcg acgcgacctg cccgctggtg
    16861 atgaaggtgc acagcgaggt caagcgctac accgggcgcg gggacacggt gttcctgatc
    16921 gggcacgccg accacgaaga ggtcgagggc acggtcgggg aggcgccgga gcggatcgtg
    16981 gtggtcgagg acgccgaggc ggccgcgcac gtgcgcgcgc ccgacggcgg ccgggtggcc
    17041 tacgcgatgc agaccaccct ggccgtcgac gaagccgagg agatcgcctc ggtgctgcgc
    17101 aagcggttcc cgtcgatcga ggggccgcgg cgcgacgaca tctgttacgc caccaccaac
    17161 cgccagcgcg cggtgacgac ggtggcggag gaggcggacc tcgtcctcgt ggtcggctcg
    17221 gcgaactcgt ccaactcgct gcgcctggtc gaggtggcgc ggcggcgggg gacacgcgcc
    17281 cggctcgtcg acgacgtgtc cgaagtggac ctgcgctggc tggccggtgc gacgcggatc
    17341 gggatcaccg cgggcgcctc ggccccaccg gacctggtgg ccgagctggt gcggtgcttg
    17401 cagggactcg gccgcacccg cgtgaccgag accgtgcggg ccgatgaaga cgtggttttc
    17461 acattacccc gggaggtgag ctagaccatg gcgatgccgt tacgccagtc gatccggctg
    17521 ggcgcgttcc tggccaagca gaagctgctg cgcaaggaga agtacgcgat cctggtcgag
    17581 ctggaaccgt tgttcgcgtg caacctcaag tgcggtggct gcggcaagat ccagcagccg
    17641 gcgcatctgc tgaagcagcg gatgccggtg cagcaggccg tgggcgcggt ggaggagagc
    17701 ggcgcgccga tggtgtccat cgccggtggc gagccgctga tgcacccgca gatccacgag
    17761 atcacccgga tcctgctgga gcgcaacaag atcgtgttcc tgtgcacgaa cgcgctgctg
    17821 ctgcccaagc acatccacaa gttcaagccg caccgcaact tcacctggat ggtccacatc
    17881 gacgggctcg aggagaagca cgacgcgtcg gtgcgcaagg agggcggctt ccaggccgcg
    17941 gtcgaggcga tccagctggc gaagtcccag ggcttcaagg tgatgacgaa cacgacgttc
    18001 ttcaacaccg acaccccgca ggacgtcatc gacgtgctgg actacctcaa cgacgtggtc
    18061 aaggtcgaca acatgcagtt gtccccgggg tacgcctacg agaaggcccc ggaccaggag
    18121 cacttcctcg gggtgcagca gacccgggag ctgttcgcca aggccttcgc cgacgggcgc
    18181 cgcaagaagt ggcggctcaa ccactcgccg gtgttcctcg acttcatcga gggcaagcgg
    18241 gacctggagt gcacgccgtg ggggatcccg tcctactcgc tgctgggctg gcagcggccg
    18301 tgctacctgc tcgacgacgg ctacgccaag acctggcggg agctgatcga ggagacggag
    18361 tgggacaagt tcggccgcgg gaaggacccg cggtgcgcca actgcatggc gcactgcggc
    18421 tacgagccga cggccgtgat cgcgacgacg agcagcctga aggagacgat ccgcgccgcc
    18481 gtgagcgtgt gagcgtgccg gccccgcctc cccgtccgga ggcggggtca gctctcgaag
    18541 aactggtggt ccacggcgat gcgcccgtcg gcggccaggg tcaggacctc cagcccggtg
    18601 ctgcgcaact gcccgctgcc gtcgacgagt tcccagttga acttgacggt gtcgccgagc
    18661 cggtcggtgt tgccgccggc tctgagcgtg acccccgcgg gcgccaggaa gtcctcgtac
    18721 ccgcggcgca cccgctcctc gatggcggcg tagccgcgtg cggccaggac cgcgtcgccg
    18781 aagccgaggg cgatcgcccg gtcccgcatc tcccggggcg gttgcagcag gtgcacgccg
    18841 tcctcgtgcc acagcagctc gatcgccttc cggcgggcat ccgcgccggt ttccttccac
    18901 agcgcgacgt agcgttccac cagatccatg gcggtagcct cgccggagcc ggggcagacc
    18961 ggcaattccc gcccgggtat caggcccggg ccgcggccca ctccgggtag ccgtcctcca
    19021 ggcgggctgc ccggtggccg gccgcggtca gcagccggac cgcgtcgtcg gcgtagacgc
    19081 agtacgggcc gcggcagtag gcgacgacct gggcgccgtc cggcacctcg gtcagccgcg
    19141 cccgcagctc ggtgatcggg atcgacacgg cgcccgggat gtggccggcc gcgtactccg
    19201 gggccgggcg gacgtcgagc accaccacgt cgccgtcgcg cagccgccgg tccagctcgt
    19261 cgcgcgtgat ggtgtccagg ccggagcggt cgccgacgta gtcctcggcg agccgggtca
    19321 ggccctcgac gtgctcctcg gccgcggcgc gcatcgccag ccacaaccgc gccacggcgg
    19381 cgccggccag cgagtagaac acccgcgttc cctcccggcg ggtccgcacc aggccggacc
    19441 gcaacagccg ccgcaggtgc tgggaggtgt tggccaccga ctggccgatc tcggcggcga
    19501 gctcgtcgac cggccgctcg ccctggacga gcacgtcgac cagctccgca cgccgtccgc
    19561 tggcgagcgc cttcgcggtc tcggccagcg cgtcgtacag ctcggtcttc gcggcccggt
    19621 cacccatgcg gagcaggata ttcaagagaa ctcttgacaa gcaacccggc gcggggctct
    19681 tattcaagaa gtcacttgaa caagcgcgga ggtgcgcgat gaccgcgacc gtggacaccc
    19741 tcggtgcagg atccgagcgc ggacgccggg atcgcgtcga ccgtcccggc ggcgcagcca
    19801 gcccggctcg cgaccccgag ccccagctcg aagtggaaac tcgcgcccgc ctagccgctg
    19861 aggcgggcgc cggcgccgac ggccacgcgc gcatccccgg ccgggcacgg gacgccggcg
    19921 tgcacagcgt gtccgtcctc gccacaagcg cgggagggtg agtgccgtgt cgactgtgga
    19981 cgtcctgccg ctcgtggacg aggggctcgg caactcggcc tacctggtcg acctcggcga
    20041 cggccgggcc ctggtcgtcg acgtgagcct ggacctgcgg gccgcccggc gcgccgcccg
    20101 ccgccggggt ctgcgcctgg ccttcgccgc cgacacccac ctgcacgccg acttcgtctc
    20161 cggcgcccgg cagctcgcgg tcaccgacgg cgcccgcgtg ctggcctccg cggccgggca
    20221 gcgcgagttc acccacgacg ggctgcgcga cggggacgag accgacctgg gcggcctgcg
    20281 cctgcgcgcc ctgttcaccc ccgggcacac gcacgagcac ctgtcgttcc tcctgctcga
    20341 cggcgacacc ccggtcggcg tgttcaccgg cggctccctg atcgtggggg ccgccgcccg
    20401 caccgacctc gtcgacccgg accggaccga cgagctggcc cgccgccagt acgcctccct
    20461 gcgccggctg gcgaccctgc ccgacgaggt cgcggtgtgg cccacccacg gcgccggctc
    20521 gttctgctcc gccccaccgg gagcacggcg caccagcacg atcggcaccg agaaggcgac
    20581 gaacacgttg ctgcgcgcgg aaaacgagga cgccttcgtc acggcgctgc tcgattccct
    20641 gggcagcttc ccgtcctact tccgcgaact ggccgacacc aaccgccgcg gcgtggtcct
    20701 ccccggtgac cccaccttgc ccgggctcga cgtggaccgg gtgcgcgggt tgtgcggcga
    20761 tggcgccgtg gtggtcgacg cccgccccgc cgccgacttc gccgccggtc acctgccggg
    20821 tgcgctgtcg aacccgctgc gcccggcgtt cgcgtcctgg ctcggctggc tggtgcccgc
    20881 cggccgcccg atcgtcgtcg tgcgcggggc ggaccaggac ccggccgaga tcgcctggca
    20941 ggcggtcaag atcggccgca ccgacctggc cggcgaactg gccggcgggc tggacgcgtg
    21001 gaccgccgcc gggcagccgg tgcgccgcac cccggtcgtg acccccgccg ggatcggccg
    21061 gcggccggtg ctcgacgtgc gccaggacgg ggagttcgcc gccggtcacc tgcctggcgc
    21121 ccgccaccgc gagctgggcc gcctcgaccc gcgcgagctg ccgcgcgaac cgctggtcgt
    21181 gatgtgcggg cacggcgaac gggcgatgag cgcggccagc ctcctcgaac aggccggtca
    21241 ccacgaggtc gcggtgctgc tggcgagcgg ccccgcggac tgggcccgcg cgaccgggaa
    21301 cgcgctggtg accggagcgt gacggtccgg ctgggcctgc gcgccaacct ggcccagttc
    21361 accctgctgg tcgccgtcaa cgccctggtc ggcggcgtgc tgggccagga acggaccgtc
    21421 ctgccgctgc tcgccggacc ggtgttcggc ctaagcggct acaccgtcct gctcacctac
    21481 gtgctcgcct tcggcctcac caaggccgcc gccaactacc tcgccggcac cctgtccgac
    21541 cgccacggcc gcaaacccgt gctgctggcc ggctggctga tcgccgtgcc ggtgcccgcg
    21601 acgctcgcgc tggccccgga ctggggctgg atcgtcgccg ccaacgtgct gctcggcctg
    21661 agccagggcc tgacctggtc caccaccgtc atcatgaaga tcgacctcgc cgggccccgg
    21721 cggcgcggcc tcgcgatggg gctcaacgag gccgccgggt acggcgccct ggcactcacc
    21781 gccgccgcca ccggctacct cgccgcgcac ttcggcctgc gcccggcgcc gttcctcctc
    21841 ggcgcggcct acgtcgccct cggcctgggc ctgaccgcgg cgttcgtgcg cgaaacccgc
    21901 gaccacgccc ggtccgagtc ccaccccgcc accgccgtcc tgagcggctg ggccgtgttc
    21961 gcccggacca gcgtgcggga ccgcgcgatg tccgccgcca gccaggccgg gctggtcaac
    22021 aacctcaacg acggcctcgc catgggcctg ttccccgtcc tgttcgtcac caccgggctg
    22081 tccgtcgccg gcgcgggcgt gctcgccgcg ctctaccccg cggtgtgggg cgccgggcag
    22141 ctcgtcaccg gcccgctgtc cgaccggtgg ggccgcaaac acctgatcac cgcgggcatg
    22201 ctggtgcagg ccgccgcgct cggcctgacc gcgctcggca ccgggttcgc ggtgtgggcg
    22261 gtggcgatgg tgctgctcgg tgccggcacc gcgatggtct acccgacgct gctcgcggtg
    22321 gtcggcgacg tggcgcaccc ggcgtggcgg gcccgcgcgg tcggcgtcta ccggctctgg
    22381 cgggacagcg gcttcgcggc cggggcggtg gtgtccgggc tcgccgccga cctgtggggg
    22441 ctgcgggcgg cggtggcggt cgtcgccgcg ctcaccgccg cctccgggat cgcggtcgcg
    22501 atccgcctgc cggaaacgct ccgccggagc tgactcacgg gatcagcagc accttgccgg
    22561 tcgtgcggcg gccctgcagg tcctcgtgcg ccttcgcggc ctcggccagc gggtacttcg
    22621 ccccgacccg gaccttcagc gcgccggagg cgaccgcctc gaacagttcg cccgtgcgcc
    22681 actccagctc ctcgcgggtg cgcacgtagt gggccgaggt cgggcgcgtc aggtacaccg
    22741 agccggccgc gttcagccgc tgcgggtcga acggcggcac cggtccgctg gccgcgccga
    22801 acagcaccag gaagccccgc acccgcacgc tcgccaggct tccgtcgaaa gtggacttgc
    22861 cgaccccgtc gtacaccgcg gccacaccct cgccgccggt cagcctccgg acctcctcgg
    22921 cgaagtcgac ctggtcgtac cggatcacct cgtccacacc ggcctcccgg gccagcgccg
    22981 ccttctcctc ggtcgacacc gtgccgatca cccgcgcgcc ccgcgccttc gccagctgcg
    23041 tcagcaacag cccgacgcca cccgcggccg cgtgcaacag gatcgtgtcg ccgtcctgga
    23101 cctcgtaggt cgaccgcacc aggtagtgcg cggtgatgcc ctgcagcatg gtcgcggcgg
    23161 ccgtctccgc cgagacaccc tcgggcaccg gcaccgcggc gctcgccggg atcagggccc
    23221 gctgcgcgta accgccgagc acgccctgcc acgccacccg gtcgccgacc gcgaagcccg
    23281 acacgccctc gccgacggcg gcgaccgtgc ccgcgccctc catgcccagc gtcgcgggca
    23341 ggtcgatctt gtagatcccg ccgcgttggt aggtgtcgat gtagttcacg cccgcggcgg
    23401 cgacgtcgac cagcagctca cccggcccgg gatcgccgat ctcgacgtca ccggcctcca
    23461 gcacctcggg tccgccggtc cgccgaatct gcactgccgt gggcatcgcc tgtgtcctcc
    23521 tgacgtggtc gggttcacct cgcacaaccg ggtgggccgg gcggatcttc cctaagatgc
    23581 cgacatggct gaagagaccg aggcaccggc gcccaccgcc aagcagctta cgaccgcccg
    23641 ccgcttcgtc gccgagcacg gcaagccggc gaaggccgtc gtggagaaca tcggccgcgc
    23701 cggcgcccgc gtggtgctcg tcggccacga cggcgcgctg ggcgacatcg tcgtgccggc
    23761 cgtggaaacc gggcagaagc tcgtcgaggc cgtggaggac ctggaaccgg ccgagtggga
    23821 cgccgagacc accaactcga ccaagatcgg gcccggccac cgccgccgga tggccgggca
    23881 cgccctgtag gaactaggaa gcgggctcga gccgcttcgc ggcgaggcgc tcggcgcgcg
    23941 gccaccgcac gtcgcgcgcc cagcccagct tctcgaagat ccagatcacc cgcgccgaca
    24001 cgtccagctg cccgcgcagc acgccgtgcc gggcgcaggt cgggtccgcg tggtgcgagt
    24061 tgtgccacga ctcgcccatc gacaggatcg ccagtggcca gaagttcgcc gccttgtccc
    24121 ggctggcgaa cggccggtcg ccgatcatgt ggcagatcga gttcaccgac cacgtcacgt
    24181 ggtgcaggaa cgcgatgcgc accagcccgg cccagaagaa cgcggtcacc gcgccccacc
    24241 acgaccagct cagcagaccg ccgagcagcg tcggcaggcc caggctcagc acgatccaca
    24301 gccagaacag ccggttcacc acgcgcaggt cgtcgtcggc cagcaggtcc ggcgcgaacc
    24361 gctcgtagtt ggtcacctca cgctggaaca tccaccccat gtgcgcgtgc cagaagccgc
    24421 gcagcagcgc cgccgggctc gtgccgaaca gccaggggga gtgcgggtcg ccctcgcggt
    24481 cggcgaacgc gtggtgacgg cggtggctgg ccacccagaa gatgaccgac ccctgcacgg
    24541 ccatgctgcc cgcgatcgcc atggcgacgc gcagcggacg gccggtcttg aacgccccgt
    24601 gcgtgaagta ccggtggtag ccgaccgtca ccccgagggt ggcgacgacg tagaagaaca
    24661 ccgccaagcc caggtcgagc caggtcaggc cccagcccca cgccagcgga acggcggtga
    24721 tcagggcgag gaacgggatc agcaggaagg ctttgagcac gatcatctga ccggaggacc
    24781 ggcgatgcga gatcagcggt ttcgtcatgg gtggcagtaa cctctctctc cggccccacc
    24841 gtacggagcc gtcttggcga atacccccct caggcgttac taccgcatga cgggcggcga
    24901 aatcacgccc cagccgcggt cagccgcgcg ccgcggtcag ctccggctcc cggggcgccg
    24961 gcccgtccga ggtgaccggc ccgcggtcgc ggcagccgca ccacagcgcc gcggtcgcca
    25021 cgatcaccag cgccgagccc agcacgtgca gcgacaccag tgcctccggg atgcccagcg
    25081 cgtactgcac cgaacccagc acaccctgcg cgagcgccac cagccacacg atcgagtacc
    25141 gccgccacac caccgccggg gtgccgccgc gcatcagcac caggccgaag accgcgagca
    25201 ccagcaggta gaggacgagc agtccgccgt ggacctgggc gagcacctcg atcggcgcgt
    25261 ccagacggtg ggtctccggg tcgccgccgt gcgggcccgc gccggtgacg gtggtgccgg
    25321 cgatcaggat cgcccacagc gcgaccacga gcgtgaccag cagcttcttc gccagcggcg
    25381 ggacgagcca gcgggccggc cggtcgccct cgttgaacgc gcgcagcagc agcaccgcga
    25441 gccacaccag cggggtggag gcgaggaagt ggatcgcgac cgtccaccat tccagcttcg
    25501 cgagcaccgt gatgccgccg accacggcct gcagcacgac cccgccgggc atcgtccagg
    25561 cgagccggac cagccgcttg cgctcggggt gggcgatctg cacgcgccac gcggcgagca
    25621 ccgccagcgc ggagaccagc acgaccacga cggtgagcat ccggttgccg aactcgatcc
    25681 actggttgag cgtgtcgaat tcggggtgcg cgaccggcac catgctgccc gggaagcact
    25741 gcggccaggt cgggcagccc agacccgatc cggtgacccg gacgaccgaa ccggtgaccc
    25801 cgatgccggc ctgggccacg atcgcggcga cggcgatcgc gcgctgcacc gggcgcgacg
    25861 ggtagggcag gcgggcgatc agggacttca gggccacggc aacatcctag agttatgtca
    25921 gtttcgtcgt tttcgcggcc acggctgccg ccagcgcgcc ccacacggcg agcacgagga
    25981 ccgggccgac ggcgaaccgc ccgtcgacga gc
//
