LOCUS       NZ_BNAU01000003        26145 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Amycolatopsis deserti strain CGMCC 4.7677 sequence03, whole genome
            shotgun sequence.
ACCESSION   NZ_BNAU01000003
VERSION     NZ_BNAU01000003.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Amycolatopsis deserti
  ORGANISM  Amycolatopsis deserti
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 656261)
  AUTHORS   Sun,Q. and Zhou,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 82X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014653945.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:43:30
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,561
            CDSs (total)                      :: 7,498
            Genes (coding)                    :: 7,407
            CDSs (with protein)               :: 7,407
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 32 of 91
            Pseudo Genes (incomplete)         :: 64 of 91
            Pseudo Genes (internal stop)      :: 8 of 91
            Pseudo Genes (multiple problems)  :: 12 of 91
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:49:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 304198
            Orig. end                         :: 330343
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BNAU01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26145
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="2"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..26145
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26145
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16145](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16145)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            828..1967
                     /locus_tag="IE290_RS16120"
                     /old_locus_tag="GCM10017786_32730"
     CDS             828..1967
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017986489.1"
                     /locus_tag="IE290_RS16120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32730"
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="WP_191245387.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 6.2e-34,
                     bitscore: 112.4, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVAINLLTDDPFNPSGAHWFWTRVIPEMTRLLRDGESFHLMVSP
                     KSRPTHDYGSSVGYITYPWSNEKRNLRTLSEHVYSPLRLPLSGIDVLNTLMAPIVKSAP
                     KLVVHIKTLHAYTTPHAISPPARLYRQLSYPRTARLADAIILNSRSLVDEVQQYLKVDP
                     AKIRLIPEAVDHDLFNPGDRDEAFAHVAKRYGVRENFVLFVSSLWPYKNCEGLIRAFAA
                     AKSDLGDRQLVVVGPGRDVEYVGELKALAARLGVADDIVWVGGVPLEETVHFYRAADVF
                     VYPSHNETFGLPILEAMASACPVVTSNVTAMPETAGGAALLADPKDADSIADQIVKACG
                     PEGERLRARGPERAGEFTWAATAARTLDVYREVHEGHTV"
     misc_feature    854..868
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.75"
                     /tool="antismash"
     gene            1964..3076
                     /locus_tag="IE290_RS16125"
                     /old_locus_tag="GCM10017786_32740"
     CDS             1964..3076
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (4-257). E-value: 3.5e-16.
                     Score: 51.0. Matches aSDomain:
                     nrpspksdomains_IE290_RS16125_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020417464.1"
                     /locus_tag="IE290_RS16125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32740"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_191245388.1"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 2.2e-07,
                     bitscore: 25.5, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 3.7e-15, bitscore:
                     51.0, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLVTGGAGFIGSHTCDRLVELGHEVTVLDVLAAPVHRDGKPNH
                     LTPGVEFYESDVRNRDLMRNLLRRADAVYHFAAYQDYLPDFAKFTDVNVTSTAMIYEIA
                     VAEKLDLARIVVASSQAAMGEGLYRCAEHGEQTPDMRPESALRAGRWDIGCAVCGEPLE
                     MLPTPERIANPQNAYGMSKHGEEVVAVNLGRRYGIPTVALRYSIVQGPRQSVYNAYSGA
                     CRIFNLHYLLGGAPTLYEDGQNVRDYVNIHDVVDANVLVLADDRAAGRVFNVGGGTGYT
                     TQEFAEIVRRQYGSDRPGRISGEYRFGDTRHITSDIDALKQLGWSPKRTPADSVAEYAE
                     WLRDMPGLDEILAEADAKMRSLGVVRKAVT"
     CDS_motif       1973..2035
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE290_RS16125_0001"
                     /evalue="1.60E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE290_RS16125"
                     /protein_end="24"
                     /protein_start="3"
                     /score="14.3"
                     /tool="antismash"
                     /translation="LVTGGAGFIGSHTCDRLVELG"
     aSDomain        1976..2734
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE290_RS16125_NAD_binding_4.1"
                     /evalue="3.50E-16"
                     /label="IE290_RS16125_NAD_binding_4.1"
                     /locus_tag="IE290_RS16125"
                     /protein_end="257"
                     /protein_start="4"
                     /score="51.0"
                     /tool="antismash"
                     /translation="VTGGAGFIGSHTCDRLVELGHEVTVLDVLAAPVHRDGKPNHLTPG
                     VEFYESDVRNRDLMRNLLRRADAVYHFAAYQDYLPDFAKFTDVNVTSTAMIYEIAVAEK
                     LDLARIVVASSQAAMGEGLYRCAEHGEQTPDMRPESALRAGRWDIGCAVCGEPLEMLPT
                     PERIANPQNAYGMSKHGEEVVAVNLGRRYGIPTVALRYSIVQGPRQSVYNAYSGACRIF
                     NLHYLLGGAPTLYEDGQNVRDYVNIHDVVDA"
     gene            3073..3771
                     /locus_tag="IE290_RS16130"
                     /old_locus_tag="GCM10017786_32750"
     CDS             3073..3771
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017986487.1"
                     /locus_tag="IE290_RS16130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32750"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_191245389.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 3.7e-13, bitscore:
                     45.4, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAFLLAAGLGTRLRPLTDHTPKCLVEIGGRPMLDIWLDALAAAG
                     VDEVLVNLHHLAPLVRAHLADRRGGPVVHTVEEPELLGSAGTLWTNRSFVAGEEMFLAL
                     NADNLTDFDPRVLIDAHRAGGAIATLSVFHAPDPTRCGILTVENGLVTDFTEKPAEPSS
                     DLANAGMYAFSPAVLDLIGPPPRDIGYDLLPKLVGQARVVSLGDSWFLDIGTPAALARA
                     RDEWQSRRAS"
     gene            3747..4757
                     /locus_tag="IE290_RS16135"
                     /old_locus_tag="GCM10017786_32760"
     CDS             3747..4757
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020417462.1"
                     /locus_tag="IE290_RS16135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32760"
                     /product="GHMP kinase"
                     /protein_id="WP_229874528.1"
                     /transl_table=11
                     /translation="MAKQASIVIITQTPLRIGLVGGGTDLPGYYREHGGRVLNAAIDKY
                     VYVVVKQRFDDEIYVNYSRKEIVSRVEDLEHELVREAMHMTGVRSGVEITTLADIPSAG
                     SGLGSSSSVTVGLLHALFAYQGRQVTAEELADRACAIEIDRCRKPIGKQDQYAAAFGGL
                     CDLHFGPGDAVGVEQIDLPRADWRKLQDELMLFFTGITRSADTILGEQNANVGSKLSQL
                     GQLRDLAGEAADGLRGGDLSALGTALRKSWEAKRSLASGVSNQQIDEAVDAALSAGASG
                     AKVTGAGGGGFLLVSCPLEHQQAVRARLAGMKELPIKLERLGSRIIFNVHRDIWS"
     gene            4741..5415
                     /locus_tag="IE290_RS16140"
                     /old_locus_tag="GCM10017786_32770"
     CDS             4741..5415
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020417461.1"
                     /locus_tag="IE290_RS16140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32770"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_229874529.1"
                     /transl_table=11
                     /translation="MTSGADELTPHPAVPAALRAPLAAIAVAAAAVAVLLGVLVTGDST
                     GTAVDRSAYTAWQDSVREPSLSFDVSWAIGTAGDPAWAAGLVVLLAALCFAVGRRRLAL
                     LAVAGPAATGVITTLVKPVVDRTINGDHLSYPSGHTALLTSLGIVAGLLLTDRFRLGRA
                     RGLPLVLGLAVLCGAAMSWSQTASRVHYLTDTLGGFCTALALVVAAGWLIDRVADRVKV
                     TG"
     gene            5475..7016
                     /locus_tag="IE290_RS16145"
                     /old_locus_tag="GCM10017786_32780"
     CDS             5475..7016
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020417460.1"
                     /locus_tag="IE290_RS16145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32780"
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="WP_191245390.1"
                     /transl_table=11
                     /translation="MQTSSRAAALTLGAGVLALAATVAVVAPDSAAPPAVAPAVQAAPA
                     QTALVQQPPAAVCDSPALAGPASPPAGAVVVPAGSNAGFDFSTPDTTYWFAPGVHTLAP
                     GEFSQIAPGPGVTLLGGPGAVLDGNRDNRYAITGRAANVTIRHLTIRNFVAPRDEGVVN
                     HDSGDGWTVEHNTLTRNRGAALMAGARNRIAGNCLKDNGQYGLNAYQSGNRITGLVVEG
                     NEFTGNNTEDWESQLPGCGCTGAMKFWAVNGADVRNNWIHGNRGTAVWADTNNNDFLIE
                     GNLIEDNDGTGIFYEISYNAVIRGNTLRNNAWATGREFAGERDPFPVGAIYLSETDGDA
                     RIPARTAKIEVTGNLLENNWGGVVGWANADRFCNSSASTTSDCTLVVGPDNTSACSPPA
                     IAREPLYTDCRWWTSGLDIHGNTFRFDPAAVDGGCPPEFCGRMALLSNYGSSPDWSPYQ
                     GDVIQRHIVFEAGNRWHDNTYTGPWRFTVPDMSTTVPVPQWTGAPYHQDAGSTFG"
     gene            7028..8155
                     /locus_tag="IE290_RS16150"
                     /old_locus_tag="GCM10017786_32790"
     CDS             7028..8155
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF026257.5"
                     /locus_tag="IE290_RS16150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32790"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_191245391.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 7.7e-42, bitscore:
                     138.8, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRRLCAESEYPAALLAVAAYRLPGSDRAFPAEPVGAEEWPGLLA
                     AARKHRMTGLLTAAITAGAFPATGEQAREVKSAHATNQMRVLVLEHELLRILDLLAGAR
                     IEARVLKGTAVAHLDYPDPALRSFNDLDVLVRAGDIDRTVEALRTAGFQRTLAEPRPGF
                     DRRFDKGMTLRPPAGYELDLHRTFVLGPWGRRVDLDAVWDEGQEFTIGGRAVRALSLPN
                     RFLHACYHAALGDWPLRLGSLRDVAEMLRVVDPGQVRRLAASWGAEAVVAAAVADTVRL
                     LGIKVPGELAHWAVAYVPSPRDESWLGLHTTPDKTFAAQAVATLRVLPWRDKPAYLRAL
                     VFPDASYTADRHRSVLSRFGYALREVRKGSPTGRR"
     gene            complement(8162..9100)
                     /locus_tag="IE290_RS16155"
                     /old_locus_tag="GCM10017786_32800"
     CDS             complement(8162..9100)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE290_RS16155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10017786_32800"
                     /product="hypothetical protein"
                     /protein_id="WP_191245392.1"
                     /transl_table=11
                     /translation="MTAHRTAALLAAVLLVAGAPATARAHPGPSRLADVRVLAHFDRAA
                     GQAAESIAPQPGGGAVIGMIPARQVVRVAPDGAVQVLVTMPLPPGGGGTTPVVGAPVVT
                     GVARSGSGDVYFLYSAGQGALTGIWRLGRSGEPRLVVPLPADTMPNALVIDRDRVLVTD
                     SADGRIWQAPLRGGAASVWSADPALAPDGFFGANGLKIHDGAVWASNSDRGTIVRIPVT
                     GGRAEVRATGLAGIDDFDFTGRGDEILAAINQASELVRVGADGSHDTLLDAADGMQGTT
                     AVVVRGHRVYVTNGANLVGNDSNLLVAELRR"
     gene            complement(9097..9948)
                     /locus_tag="IE290_RS16160"
                     /old_locus_tag="GCM10017786_32810"
     CDS             complement(9097..9948)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020417457.1"
                     /locus_tag="IE290_RS16160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32810"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_191245393.1"
                     /transl_table=11
                     /translation="MARDELAEFLRRRRALLQPADVGVPAGGRRRRPGLRRFEVAQLAG
                     MSPDYYARVEQGRGPQPSVTVLAALARALRLTTDERDHLFRLAGHHAPPCAGGDEHVSR
                     GLLRLLDGVTGLPALIASDLNIVLAQNAMADALLGEQTRFRGLARSCTYRWFTDPAMRE
                     RHPAEDHEHESQAQVADLRATLAARPADRAAGELVEALRAASAEFAGLWDRHDVAVRRS
                     DRKRIRHPAVGLIELDFDVLATARQDQRLIVYSPAPGSAAVSQLELLAVLGQETFTTEG
                     EA"
     gene            complement(10001..11131)
                     /locus_tag="IE290_RS16165"
                     /old_locus_tag="GCM10017786_32820"
     CDS             complement(10001..11131)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017986483.1"
                     /locus_tag="IE290_RS16165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32820"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_229874530.1"
                     /sec_met_domain="Asn_synthase (E-value: 1.5e-17, bitscore:
                     59.6, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALYTMDRLEIAGGWINGYDLVPLPLGDPGEPRRVLDRILLGHLT
                     RTPCLVAFSGGRDSSALLAAAVSLARREGLPLPVPITLRYPAAPGSDESAWQDAVLAHL
                     GITERIVLTVDDEHDPVGPIATAVLRRHGLVWPPNFAPTWRMMDAARGGVLLTGEGGDE
                     VFGLKRITPLTKVLKARGRVPARVFTDAVRALAPASVRRRAVLRARYRRPWLRPAAEEV
                     LAERDAADAAAYELHAGRHAWQFTTRRCARLGYRTVRALGSELDCRYVQTFAEPDFVAA
                     IARAAGFWGWSGRTATMRDVFGDLLPREVLERTTKADFTGAVFTERTRAFAREWTGRGV
                     DAELVDAEALRDNWLSPSPHAPSMTLLQQAWLATSG"
     gene            complement(11219..11359)
                     /locus_tag="IE290_RS16170"
                     /old_locus_tag="GCM10017786_32830"
     CDS             complement(11219..11359)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017986482.1"
                     /locus_tag="IE290_RS16170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32830"
                     /product="hypothetical protein"
                     /protein_id="WP_191245394.1"
                     /transl_table=11
                     /translation="MREPYATPEITLLGSVTDLTQANLFGQAPDNLTWALPILGDNDTY
                     S"
     misc_feature    complement(11403..11418)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.71"
                     /tool="antismash"
     gene            complement(11404..11541)
                     /locus_tag="IE290_RS16175"
                     /old_locus_tag="GCM10017786_32840"
     CDS             complement(11404..11541)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020417455.1"
                     /locus_tag="IE290_RS16175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32840"
                     /product="putative RiPP precursor"
                     /protein_id="WP_191245395.1"
                     /transl_table=11
                     /translation="MKKEYAAPGIEDIGTLSELTLGQSSGSRLDADFAAGSLFGDLTFS
                     "
     misc_feature    11677..11691
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.86"
                     /tool="antismash"
     misc_feature    complement(11679..11690)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.9"
                     /tool="antismash"
     gene            11710..13476
                     /locus_tag="IE290_RS16180"
                     /old_locus_tag="GCM10017786_32860"
     CDS             11710..13476
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020417453.1"
                     /locus_tag="IE290_RS16180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32860"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_191245396.1"
                     /transl_table=11
                     /translation="MGIRSVAATPRLITAAAREVAAADRFGTATAAVYQIVGAVGALGV
                     VAASKLTFDALLQPDHARFGLTVSLLALAFTTALSGSVTALQTQQHRLLGERVSQRVWD
                     RVLDTTARADLVTYESAGFATSLERVQQNALTRPFAVTTALLGLTGSLLGVVTMSAVLI
                     GVEPLLVPILLAAGLPAVLLARWASRTEFAFAHRLTPLFRRRNYLRQLLTQRPYAAELR
                     AFHSTKPLRARHGELNAGINGALRQQVRRRQVIAGLTTVGVALSLTAALLAIIGLVRSG
                     RIDLPAAGAAAIAVRLLSSQLGTLFTSIGGLLESAPFLADLERFVASAPRSAAAGAKRP
                     LRQGVVLRDISFRYPEQERPAVDSVDIEIGAGEVVALVGENGSGKTTLAKIVAGLYDPD
                     LGTRRWDGTDAPAADIRASVTVIFQDFVRYQMTLRDNITISDGDRPADEESVHDAARRA
                     GVLGVTRELPHGLDTMLGRDLDEGFDLSGGQWQRVALARALYRDTSLVVLDEPAAALDP
                     RAEHELFTDVRAMLGGRAALLISHRFSSTRMADRIYVLDAGRVVECGTHDELMARAGQY
                     AELYRLQSAAYR"
     gene            complement(13459..14376)
                     /locus_tag="IE290_RS16185"
                     /old_locus_tag="GCM10017786_32870"
     CDS             complement(13459..14376)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017986479.1"
                     /locus_tag="IE290_RS16185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32870"
                     /product="hypothetical protein"
                     /protein_id="WP_191245397.1"
                     /transl_table=11
                     /translation="MDFTYQAHGLTVWSDVELALPPGDGGEPDLVLRRGSDRTVPRAEL
                     PGRCLAELAKPDGRVFYTLATDGDRTVLRYPSLCEFVGDVRLREVTYHLDPSADHGLLT
                     VLATGALLAIHLTLNSHLVLHASAVRVDDRALAFVGASGMGKSTLAAALCGYGCDLVAD
                     DVLRVDPGALVYPGSTENRLRMAARGLADGAAAEDVRPTADGRLALRSTVSASALPLAA
                     CVIPRPSRSATDVSVERITGARAFVRMSQFPRVLGWRDPAVMDFAFQRLADLVAQVPVF
                     EATVPWGPPFRDEVLADLLSAVGR"
     gene            complement(14382..14798)
                     /locus_tag="IE290_RS16190"
                     /old_locus_tag="GCM10017786_32880"
     CDS             complement(14382..14798)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017986478.1"
                     /locus_tag="IE290_RS16190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32880"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_229874531.1"
                     /sec_met_domain="PF13471 (E-value: 2.7e-13, bitscore: 45.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRWRRRARLAWEVLRALPPMVRIEFRLRRSDLRETCRRLGVRCDL
                     TSTEPPSAEAPVLPRWSRAPIRASYFVVSRWPAGDTCLRQCLLIGHRLRELEPVLRIGV
                     RREDGRFAAHSWLEIDGRAMDPMAARYAVLGSAG"
     gene            complement(14795..15913)
                     /locus_tag="IE290_RS16195"
                     /old_locus_tag="GCM10017786_32890"
     CDS             complement(14795..15913)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017986477.1"
                     /locus_tag="IE290_RS16195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32890"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_191245398.1"
                     /sec_met_domain="Asn_synthase (E-value: 3.5e-15, bitscore:
                     51.8, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSSSTEAPPRLSTLDIAAGQPLGVAPFPLGVPTDPVLALRNAVR
                     PALLREPCVIAFSGGRDSSVLLAVAADLAAREGLAPPIALTFRYPGDAAADESAWQEAV
                     IRHVGVDTWARRDIDGELDLIGPLVRPVLRARGPVYPAALGNTMLLASHAPGGSLVTGN
                     AGDEVLGGHRLGTLRAVARRRGRGMTGADWAQFALCAAPAFARRRLARRSLPMPWLRPD
                     VRRTLWRAAADRPLRWETSVRTALATRAFSVGFRTRADAAAEYGCELVEPFADPTFVAS
                     YAAVAPMTRAAGTRLVADGLLPEAVLTRRDKARFNASRFGARSREFARNWDGSGVDASL
                     VDPDALRTAWLADEPPASTAMLLQQAWLAEAA"
     gene            complement(15894..16145)
                     /locus_tag="IE290_RS16200"
                     /old_locus_tag="GCM10017786_32900"
     CDS             complement(15894..16145)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017986476.1"
                     /locus_tag="IE290_RS16200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32900"
                     /product="PqqD family protein"
                     /protein_id="WP_191245399.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 7.7e-21,
                     bitscore: 69.3, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 9.2e-18, bitscore: 59.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVRASDISARTIGDETIVLSLSTSKYFTITGVGTRLFELLAEER
                     SVEDLVGAITSEYEIDADTARRDIEAFLGRLRDAELLH"
     aSDomain        complement(15900..16133)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_IE290_RS16200_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="3.40E-22"
                     /identifier="RREFam002.1"
                     /label="IE290_RS16200"
                     /locus_tag="IE290_RS16200"
                     /protein_end="82"
                     /protein_start="4"
                     /score="69.3"
                     /tool="antismash"
                     /translation="ASDISARTIGDETIVLSLSTSKYFTITGVGTRLFELLAEERSVED
                     LVGAITSEYEIDADTARRDIEAFLGRLRDAELL"
     gene            16277..16912
                     /locus_tag="IE290_RS16205"
                     /old_locus_tag="GCM10017786_32910"
     CDS             16277..16912
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020417448.1"
                     /locus_tag="IE290_RS16205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32910"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_229874532.1"
                     /transl_table=11
                     /translation="MPATVRRPLLVLAIPAAITVVVLAVHFAGTHAAGALDRWILDASG
                     GAIPFPSQQRVTAKGLDFAGEPAGAALLVTALIALCLVLGHRRAAVLAVLGPGLSVAVT
                     TLLKPVVGRTINGPHLSYPSGHTAVVTAMVLVFAFVLVDRLRLRTPAATAVVLYAAVTT
                     GAAEAWAQYGMVVHYPTDTLGGFCVALAVVPTTAWLVDRVTRRAGTPA"
     gene            complement(16884..18197)
                     /locus_tag="IE290_RS16210"
                     /old_locus_tag="GCM10017786_32920"
     CDS             complement(16884..18197)
                     /EC_number="5.4.3.8"
                     /NRPS_PKS="Domain: Aminotran_3 (41-342). E-value: 5.9e-44.
                     Score: 142.4. Matches aSDomain:
                     nrpspksdomains_IE290_RS16210_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017986474.1"
                     /locus_tag="IE290_RS16210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32920"
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="WP_191245401.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.5e-38, bitscore:
                     127.7, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDAQFLPRSTEANERLHQLVPGGAHTYAKGEDQYPEGLAPVISHG
                     RGAHVWDVDGNEYIEYGSGLRSVSLGHAHPRVVEAVRRELDRGSNFVRPSTVELAAAEK
                     FLATVPTAQMVKFAKNGSDVTTAAVRLARAATGRRVVAICADHPFFSTDDWFIGTTGMP
                     AGIPDEIAALTVRFPYGDLAATEEVLRQHDVACLILEAATAVEPPPGYLEGLRALADSY
                     GVVLIFDEMITGFRWSEAGAQGYYGVTPDLSTFGKALGNGFAVSALAGKRELMELGGLR
                     HARERVFLLSTTHGAETHSLAAAMAVMDTYVEEGVTARLHALGERLASGVRDVAAAMGV
                     GEHVVVRGRASNLVFGTLDEQLRPSQPYRTLFLRQLVAGGVLGPSFVVSSALTEADIDR
                     TVDVVAQACAVYRKALDAEDPTPWIGGRPVKPVFRPYA"
     aSDomain        complement(17172..18074)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE290_RS16210_Aminotran_3.1"
                     /evalue="5.90E-44"
                     /label="IE290_RS16210_Aminotran_3.1"
                     /locus_tag="IE290_RS16210"
                     /protein_end="342"
                     /protein_start="41"
                     /score="142.4"
                     /tool="antismash"
                     /translation="ISHGRGAHVWDVDGNEYIEYGSGLRSVSLGHAHPRVVEAVRRELD
                     RGSNFVRPSTVELAAAEKFLATVPTAQMVKFAKNGSDVTTAAVRLARAATGRRVVAICA
                     DHPFFSTDDWFIGTTGMPAGIPDEIAALTVRFPYGDLAATEEVLRQHDVACLILEAATA
                     VEPPPGYLEGLRALADSYGVVLIFDEMITGFRWSEAGAQGYYGVTPDLSTFGKALGNGF
                     AVSALAGKRELMELGGLRHARERVFLLSTTHGAETHSLAAAMAVMDTYVEEGVTARLHA
                     LGERLASGVRDVAAAMGVGE"
     misc_feature    18150..18163
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.1"
                     /tool="antismash"
     gene            complement(18203..18751)
                     /locus_tag="IE290_RS16215"
                     /old_locus_tag="GCM10017786_32930"
     CDS             complement(18203..18751)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) dTDP_sugar_isom"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013222492.1"
                     /locus_tag="IE290_RS16215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32930"
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="WP_191245402.1"
                     /sec_met_domain="dTDP_sugar_isom (E-value: 9e-52, bitscore:
                     170.4, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAVPVPGIAGAWLFEPTPHADARGFFSRTFDREVVASVGIDPDG
                     FAQDSLSRSVKGVIRGMHLRSGAGEAKLVRCSYGEVFDVVVDLRPDSPTFRNTEYFQLS
                     GDTQVSVYVPAGCAHGFQALTDPADVSYRIDRPHDPSEDVTIAFDDPDLAIPWPLPVSL
                     TSDRDRRAPSLAEVLKTLR"
     gene            complement(18748..19926)
                     /locus_tag="IE290_RS16220"
                     /old_locus_tag="GCM10017786_32940"
     CDS             complement(18748..19926)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017986472.1"
                     /locus_tag="IE290_RS16220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32940"
                     /product="polysaccharide pyruvyl transferase family
                     protein"
                     /protein_id="WP_191245403.1"
                     /transl_table=11
                     /translation="MTRIGFFGILGSGNLGNDGSLDAVLRYVRKRYPDSELGFLAMGPE
                     ELTARYGAPATHLQWYEPHAGDATGLRAAGLKVLGKLLDPFRTWAWVRNFDVVIVPGMG
                     VLEATLPLRPWALPYSLFWLGVTARLTGTRVALVSVGADVVRKRATRWVITRAARLAHY
                     RSYRDEHSRQAMARMGVDVSGDGVFPDLAFGLDGPEPRTSAGAVGVGVMAFHGGNDDRA
                     RADEINRAYLATVKRFVRLLADEGRPIRLFTGDVADAEVPAEIIAAVPGADIVAEPLTS
                     LQDLMHQMAAVDVVVATRYHNVLCALKTAKPTISLGYARKNDVLMEAMGLGEFCQSARE
                     PDFDRLVRQFRELEDRREELTAVLKERNRVMTERLERQFDIMSESVIEGSRT"
     gene            complement(19923..20777)
                     /locus_tag="IE290_RS16225"
                     /old_locus_tag="GCM10017786_32950"
     CDS             complement(19923..20777)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017986471.1"
                     /locus_tag="IE290_RS16225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32950"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_191245404.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 9.7e-33,
                     bitscore: 108.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPRLSIGLPVYNGENYVAEALDNLLAQTFTDFELIISDNASGD
                     GTQEICEKYAARDDRIRYVRQPRNIGAAPNHNFVVRAARGEFFKWAAHDDLFAPELLAR
                     CVQALDEHPEAVLAHTYMAIVDERGEVIENYDYGLATDSPDAAVRFRSLMFTEGGDDFY
                     GVIRTSVMRRIAPHDSYHNAGRKLVGELALHGTFVQVPEVMFFRREHPGRGDNLGSVQK
                     VCANLDPRREGQSKARLFAEYLAGYVTAIRRAPLSSSERRRCYAVIAEWLGGKPLRKVG
                     LLS"
     gene            complement(20774..22063)
                     /locus_tag="IE290_RS16230"
                     /old_locus_tag="GCM10017786_32960"
     CDS             complement(20774..22063)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020417443.1"
                     /locus_tag="IE290_RS16230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32960"
                     /product="hypothetical protein"
                     /protein_id="WP_191245405.1"
                     /transl_table=11
                     /translation="MTTGRHRKPAAKPSGLRAMAGRLSWGLGDQAVSSLTNFAVGIYVA
                     RELGVTAFGVFSLAWVTYGVMLNVSRGLATDPLMVRFSGVDTGVWRAAVARSSATALAV
                     GAVAGLVSVLFGIVVGGSVGPAFVALGVILPPLLLQDSWRFAFFASGEGQKSFVNDALW
                     GVAMIPAMVLAALHGSVVAFLLAWGGAAAVAAGYGYLQTGLRPSLDGVRSWLRDQRDLG
                     PRYLVENVSNSGGSQIRMYGLGAIAGLAAVGTVRGGELLLGPFLAVLMGLAYVAVPEAA
                     RVVRRNVRRLTTFCLVLGGSQALAALLWGGALLLVLNDHLGELVLGDVWRTAQAMIIPA
                     TLSVFNASFIGGAATGLRALGAARRSMRCQLIASSLYVIGGLSGAAIGGAVGSGWGVAC
                     ATFAGAFVWWSQLHVAARAHVPVPEESRTP"
     gene            complement(22109..23131)
                     /locus_tag="IE290_RS16235"
                     /old_locus_tag="GCM10017786_32970"
     CDS             complement(22109..23131)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020417441.1"
                     /locus_tag="IE290_RS16235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32970"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_191245406.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 2.2e-15, bitscore:
                     51.7, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLLTGHKGYLGTVMAPVLTAAGHEVTGLDSGLFDECVLGPKPQ
                     DPPGHRVDLRDVTPEHVSGVDAVIHLAALSNDPLGALAPELTYEINHRAAVRLARLAKD
                     AGVSRFLYASTCSVYGASGGADLVNEDAPLRPVTPYAESKVLVEDDLHELADDDFTPVY
                     LRNATAFGFSPRLRADIVLNNLVGHACLSGEVLVLSDGTPWRPLVHARDIARAFAAALV
                     APREAVHDKAFNIGTERNNVTVAEIAEQVVEAVPGSRLRITGEAGADPRSYRVDFSRFR
                     AAIPGFTCEWSVKDGAVELVEAYQRHGLTHSAFERSFTRLARLKRHREAGAVDDTLRFV
                     "
     gene            complement(23135..23776)
                     /locus_tag="IE290_RS16240"
                     /old_locus_tag="GCM10017786_32980"
     CDS             complement(23135..23776)
                     /EC_number="3.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020643153.1"
                     /locus_tag="IE290_RS16240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32980"
                     /product="PIG-L deacetylase family protein"
                     /protein_id="WP_191245407.1"
                     /sec_met_domain="PIG-L (E-value: 4.1e-19, bitscore: 64.9,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLIPERLERIVVLGAHCDDIAIGAGGTLLTLSRPGLRVDALVL
                     SGGGSEREDEERAALAAFCPGADLDVTVLKMPDGRLPAHWDEVKNALEELRARTDPDLI
                     VAPRTDDAHQDHRGLAKLVPTAFRGHLTLGYEIVKWDGDLGTPSVYVPLRDELAEKKVE
                     LLQRHYPSQRHRPWYDREAFLGLARIRGIECQARYAEAFAVRKLCLQLEG"
     gene            complement(23773..24561)
                     /locus_tag="IE290_RS16245"
                     /old_locus_tag="GCM10017786_32990"
     CDS             complement(23773..24561)
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017986466.1"
                     /locus_tag="IE290_RS16245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_32990"
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="WP_020417439.1"
                     /transl_table=11
                     /translation="MKVVLFCGGYGMRMRNGTASDVPKPMAMVGPRPLIWHVMRYYAHF
                     GHTEFILCLGYGAHHIKDFFLNYEETTSNDFVLRGGKAELLSTDIADWTISFVQTGIES
                     PIGERLRRVRKHLDGDEMFLANYADVLTDAPLPSMIERFSRSDAGASMMVVPPQSSFHC
                     VEMDEGGLVGSITAVSEMPLWENGGYFVLRQEVFDHIPENGDLVADGCAELAKRGRLLA
                     YPYRGFWKPTDTVKERYALDEAYTRGVRPWALWEKDRVPA"
     gene            complement(24558..25796)
                     /locus_tag="IE290_RS16250"
                     /old_locus_tag="GCM10017786_33000"
     CDS             complement(24558..25796)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007030965.1"
                     /locus_tag="IE290_RS16250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10017786_33000"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_191245408.1"
                     /transl_table=11
                     /translation="MTSCRLCGSTQLASVVDLGATPPCEAFLTEAQLDESENTFPLHLR
                     VCTDCWLAQIPPLITPEETFTEYAYFSSYSESWVDHAGRFVAGAVDRLGLDGDSFVVEV
                     ASNDGYLLKHVVAQGIRCLGVEPSVNVGQAARDAGVPTLTAFLGPETGAAVRAEHGPAD
                     LVVANNVYAHIPDVIGFTKGLRALVADDGWVSIEVQHLLTLIEKTQYDTIYHEHFQYYT
                     VASAQRALASGGLSLVDVELLPTHGGSIRLWAQPAETAGEPSHRMVDVLAREKAAGLHE
                     LSGYTEFAARVARVRRDLLRFLVDAADDGLTVVGYGAPGKGNTLLNHCGIRPDLLAYTV
                     DRNPYKHGRFTPGTRVPILPPDRIAADRPDYVLVLPWNLRDELTQQLSYVGEWGGKLVF
                     PIPRLEIVEVNPT"
     misc_feature    complement(25857..25871)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.93"
                     /tool="antismash"
     misc_feature    25968..25982
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
ORIGIN
        1 cgacctggac ctgtccgcgt cctgggtggt cggcgacagc ccggccgacg tcgggctcgc
       61 ccgtgccgtc ggcgccaaac cgctgcacgt cgggccgccc ggctcggcgg tgacgggtgt
      121 ggacacgttc cccgatctgg ctgccgccgt gcggttcatc ctcgacggca gcaccgttgc
      181 ggcgccgcgg cagcagaagg cgccgaagtt cccggccgcg aagttccacc gcgcggactc
      241 cttcggcggc gcctacgtcg ccgaactggc gcgggccttc gccaccgtgg acctcgaaca
      301 ggtcagccgc gcggcgaagg tcctcagcgc cgcctacgac cgcgattcgg cggtgttcgc
      361 ctgcggcaac ggcggatccg cgtcgatcgc caaccacctg cagtgcgacc acgtgaaggg
      421 catccgcaac gggaccggcg tcaccacgcg cgtgcagagc ctgagcacca acgtggagct
      481 gttcagcgcg atcgccaacg acctgggcta cgagcacgtc ttcgaatacc agctgcagtc
      541 ccaggcgcgg ccgggtgacg tgctgatcgt catctcgtcc tcgggccgct cgccgaacat
      601 cgtgcgggca ctggactggg cggccgcgca cgacatgccg accatcgcgc tcaccgggtt
      661 cgaaggcggg gccgcgcggc gccgcgccga ggtctccatc cacgtcgact ccgccaacta
      721 cggcgtcgtc gaagacgccc accaggcgtg catgcacctg ctggcccagt acgtccgaca
      781 gtcgaggatg accccagatg ccgttgtctc gcagacattc tgaccgcatg cgcgtcgcga
      841 tcaacctgct caccgacgat ccgttcaacc cctcgggcgc gcactggttc tggactcggg
      901 tcatcccgga gatgacccgg ctgctccgcg acggcgagtc gttccacctg atggtgagtc
      961 cgaagtcgcg gccgacgcac gactacgggt cgagcgtcgg ctacatcacc tacccgtggt
     1021 ccaacgagaa gcgcaacctg cgcacgctgt cggagcacgt gtactcgccg ctgcggctgc
     1081 cgttgagcgg gatcgacgtg ctgaacacgc tgatggcgcc gatcgtgaag tcggcgccga
     1141 agctcgtggt gcacatcaag acgctgcacg cctacaccac accgcacgcg atttcgccgc
     1201 cggcgcggct gtaccggcag ctgagctacc cgcgcaccgc gcggctggcc gacgcgatca
     1261 tcctcaactc gcgcagcctg gtcgacgagg tgcagcagta cctgaaggtc gatccggcga
     1321 agatccggct catcccggag gcggtggacc acgacctgtt caaccccggc gaccgggacg
     1381 aggcgttcgc gcacgtcgcg aagcggtacg gggtgcgtga gaacttcgtg ttgttcgtgt
     1441 cgtcgctgtg gccgtacaag aactgcgaag gactgatccg cgcgttcgcc gcggcgaagt
     1501 ccgacctcgg tgaccggcag ctggtcgtcg tcggacccgg ccgggacgtc gagtacgtcg
     1561 gcgagctcaa ggcgctggcc gcacggctcg gcgtggcgga cgacatcgtg tgggtcggcg
     1621 gggtgccact ggaggagacc gtgcacttct accgcgccgc ggacgtgttc gtgtacccgt
     1681 cgcacaacga gacgttcggc ctgccgatcc tggaagccat ggcgtcggcg tgcccggtgg
     1741 tcacctcgaa cgtgacggcg atgccggaga ccgcgggcgg ggcggcgctg ctggccgacc
     1801 cgaaggacgc ggactcgatc gccgaccaga tcgtcaaggc gtgcggcccg gagggcgagc
     1861 ggctgcgcgc ccgcggaccg gaacgcgccg gcgagttcac ctgggcggcc accgcggcgc
     1921 ggacgctcga cgtctaccgc gaagtccacg aggggcacac cgtatgaggg tcctggtcac
     1981 cggcggcgcc gggttcatcg gctcgcacac ctgcgaccgg ctcgtcgagc tggggcacga
     2041 ggtgaccgtg ctggacgtgc tggccgcgcc ggtgcaccgc gacggcaagc cgaaccacct
     2101 cacgcccggc gtggagttct acgaaagcga cgtgcgcaac cgggatctga tgcgcaacct
     2161 gctgcgccgg gccgacgcgg tctaccactt cgccgcctac caggactacc tgccggactt
     2221 cgcgaagttc accgacgtca acgtcacctc cacggcgatg atctacgaga tcgcggtcgc
     2281 cgagaagctg gacctggccc ggatcgtggt ggcgtcctcg caggccgcga tgggcgaagg
     2341 gctgtaccgg tgcgcggagc acggcgagca gacgccggac atgcggccgg agtccgcact
     2401 gcgggccggg cgttgggaca tcggctgcgc ggtgtgcggt gagccgctgg agatgctgcc
     2461 cacgccggag cggatcgcga acccgcagaa cgcctacggc atgtccaagc acggcgagga
     2521 ggtcgtcgcg gtcaacctgg ggcgccgcta cggcatcccc acggtcgcgc tgcgctacag
     2581 catcgtgcag ggcccgcggc agtcggtcta caacgcctac tccggcgcgt gccgcatctt
     2641 caacctgcac tacctgctgg gcggcgcgcc gacgctgtac gaggacgggc agaacgtccg
     2701 cgactacgtg aacatccacg acgtcgtcga cgcgaacgtg ctggtgctcg ccgacgaccg
     2761 cgcggccggg cgggtgttca acgtcggcgg cggcaccgga tacaccacgc aggagttcgc
     2821 cgagatcgtg cgacggcagt acggatcgga ccggccgggc cggatcagcg gcgagtaccg
     2881 cttcggcgac acccggcaca tcacctccga catcgacgcg ctcaaacaac tgggctggtc
     2941 cccgaagcgg accccggcgg actcggtcgc cgagtacgcc gagtggttgc gggacatgcc
     3001 gggcctggac gagatcctcg ccgaggcgga cgccaagatg cgatcgctcg gcgtcgtgcg
     3061 caaggcggtg acgtgaaggc gttcctgctc gcggccgggc tggggacgcg gttgcggccc
     3121 ctgaccgacc acacgcccaa gtgcctcgtc gagatcggcg ggcggccgat gctggacatc
     3181 tggctcgacg cgctcgccgc cgccggggtg gacgaggtgc tggtcaacct gcaccacctg
     3241 gccccactgg tgcgcgcgca cctcgcggac cggcgaggtg gcccggtcgt gcacaccgtc
     3301 gaggagccgg aactgctcgg cagcgcgggc acgctgtgga ccaaccggtc gttcgtcgcg
     3361 ggcgaggaga tgttcctggc gctcaacgcc gacaacctca ccgacttcga cccgcgcgtc
     3421 ctgatcgacg cgcaccgcgc gggcggggcc atcgccacgc tgtcggtgtt ccacgcgccc
     3481 gaccccacgc ggtgcgggat cctgaccgtc gagaacggac tcgtcacgga tttcaccgag
     3541 aagcccgccg aaccgtccag tgacctggcg aacgcgggga tgtacgcgtt ctcccccgcc
     3601 gtgctcgacc tgatcgggcc gccgccgcgg gacatcggtt acgacctgct gcccaagctc
     3661 gtcggacagg cgcgcgtggt ctccctcggc gactcgtggt tcctcgacat cggcaccccc
     3721 gcggccctgg ccagggcgcg cgacgaatgg caaagcaggc gagcatcgtg atcatcaccc
     3781 agaccccgct gcgcatcggg ctcgtcggtg gcgggaccga tctgcccggc tactaccgcg
     3841 aacacggcgg ccgggtgctc aacgcggcga tcgacaagta cgtctacgtc gtggtcaagc
     3901 agcgcttcga cgacgagatc tacgtcaact actcgcgcaa ggagatcgtc tcccgggtcg
     3961 aggacctgga gcacgagctg gtgcgcgagg ccatgcacat gaccggggtg cgcagcggcg
     4021 tggagatcac cacgctcgcc gacatcccgt ccgccgggtc cggtctcggt tcgtcgtcct
     4081 cggtgacggt gggcctgctg cacgcgttgt tcgcctacca gggcaggcag gtgaccgccg
     4141 aggagctggc cgaccgggcg tgcgcgatcg agatcgaccg gtgccgcaag cccatcggca
     4201 agcaggacca gtacgcggcc gcgttcggcg ggttgtgcga cctgcacttc ggccccggcg
     4261 acgcggtggg ggtcgagcag atcgacctgc cgcgcgcgga ctggcggaag ctgcaggacg
     4321 agctgatgct gttcttcacc gggatcaccc gcagcgcgga cacgatcctc ggcgagcaga
     4381 acgccaacgt cggcagcaag ctgtcccaac tggggcaact gcgcgacctc gcgggcgagg
     4441 cggcggacgg cctgcgcggc ggcgacctgt ccgcgctggg caccgcgctg cgcaagagct
     4501 gggaggccaa gcgctcgctc gcgtccgggg tgtcgaacca gcagatcgac gaggccgtcg
     4561 acgcggcgct gtcggccggc gcgtccgggg cgaaggtgac cggcgcgggc ggcggcgggt
     4621 tcctgctggt cagctgcccg ctggaacacc agcaggcggt gcgcgcccgg ctggcaggta
     4681 tgaaggaact gccgatcaaa ctggagcggc tcgggtcgcg gatcatcttc aacgtgcacc
     4741 gtgacatctg gagctgacga gctgacaccg caccccgccg tcccggccgc actgcgcgcc
     4801 ccgctggcgg cgatcgccgt cgccgcggca gccgtggctg tcctgctcgg cgtgctcgtc
     4861 accggtgaca gcacgggcac cgcggtcgac cggagcgcgt acacggcgtg gcaggacagc
     4921 gtgcgcgagc cctcgttgtc gttcgacgtc tcatgggcca tcggcacggc cggcgacccc
     4981 gcgtgggccg ccgggctcgt ggtgctcctc gcggcgctct gcttcgccgt gggccgccgg
     5041 cgcctggcgc tgctcgccgt cgccgggccc gccgccaccg gcgtcatcac caccctggtg
     5101 aaaccggtgg tggaccggac gatcaacggc gaccacctgt cctaccccag cgggcacacg
     5161 gcgctgctca cgtcactcgg gatcgtcgcc gggctgctgc tcaccgaccg gttccggctc
     5221 ggccgcgcgc gcggactgcc cctcgtgctc ggcctggcgg tgctgtgcgg agcggcgatg
     5281 tcgtggtcgc agaccgcgtc ccgggtccac tacctcaccg acacgctcgg cgggttctgc
     5341 acggcgctcg cgctggtggt cgccgccgga tggctgatcg atcgagtagc cgatcgggtg
     5401 aaggtcaccg ggtaacggcc cttcccgcgg gggcgactcc tctagacgac cggcgtgacg
     5461 gacgggggac ggggatgcag acgagcagcc gcgcggcggc gctcacgctc ggggcgggtg
     5521 tgctcgccct ggccgccacc gtcgcggtgg tggcgcccga ttccgccgcg cccccggccg
     5581 tcgcccccgc ggtccaggcc gccccggcac agaccgcgct ggtccagcag ccgcccgcgg
     5641 ccgtctgcga cagccccgca ctggccgggc ccgcgtcgcc cccggccggc gcggtcgtgg
     5701 tccccgcggg cagcaacgcg ggtttcgact tcagcacccc ggacacgacg tactggttcg
     5761 cacccggcgt ccacacgctg gcgcccggcg agttctcgca gatcgccccc ggcccggggg
     5821 tgacgctgct cggcgggccg ggcgcggtcc tggacggcaa ccgcgacaac cggtacgcca
     5881 tcaccggacg ggccgcgaac gtcaccatcc ggcacctgac gatccgcaac ttcgtcgccc
     5941 cacgggacga aggcgtggtg aaccacgact ccggcgacgg ctggaccgtc gagcacaaca
     6001 ccctgacccg caaccgcggc gccgccctga tggccggcgc gcgcaaccgc atcgccggga
     6061 actgcctgaa ggacaacggc cagtacggcc tcaacgccta ccagtccggc aaccgcatca
     6121 ccggtctggt ggtcgagggc aacgagttca ccggcaacaa caccgaggac tgggagtcgc
     6181 agctgcccgg gtgcggctgc accggcgcga tgaagttctg ggcggtgaac ggcgccgatg
     6241 tgcggaacaa ctggatccac ggcaaccgcg gcaccgccgt gtgggcggac accaacaaca
     6301 acgacttcct gatcgagggc aacctcatcg aggacaacga cggcaccggc atcttctacg
     6361 agatcagcta caacgcggtg atccgcggca acacgctgcg gaacaacgcc tgggcgaccg
     6421 gccgcgagtt cgccggtgaa cgcgacccgt tcccggtcgg cgcgatctac ctgtccgaga
     6481 ccgacggtga cgcgcggatc ccggcgcgca ccgcgaagat cgaggtcacc ggcaacctgc
     6541 tggagaacaa ctggggcggc gtcgtgggct gggccaacgc ggaccggttc tgcaactcct
     6601 cggcgtccac cacctccgac tgcacgctgg tcgtcggacc ggacaacacc tcggcgtgct
     6661 cgccaccggc gatcgcccgc gagccgctgt acaccgactg ccggtggtgg acctccggcc
     6721 ttgacatcca cggcaacacg ttccgcttcg acccggccgc ggtcgacggt ggctgcccgc
     6781 ccgagttctg cggacggatg gcgttgctgt cgaactacgg cagctcgccg gactggtcgc
     6841 cgtaccaggg cgacgtgatc cagcggcaca tcgtgttcga ggcgggcaac cggtggcacg
     6901 acaacaccta caccgggccg tggcggttca cggtgccgga catgagcacg acggtgccgg
     6961 tcccgcagtg gaccggggcg ccgtaccacc aggacgcggg cagcacgttc ggatgacgga
     7021 ggggcggatg ggacgcaggt tgtgcgcgga gagcgagtac ccggcggcgc tgctcgccgt
     7081 ggcggcgtac cgcctgccgg ggagcgaccg ggcgttcccg gcggaaccgg tgggcgccga
     7141 ggagtggccg gggctgctcg cggcggcgcg gaagcaccgg atgaccgggt tgctgacggc
     7201 ggcgatcacc gcgggcgcgt tcccggcgac cggtgagcag gcgcgcgagg tgaagtccgc
     7261 gcacgccacc aaccagatgc gcgtgctggt gctggagcac gagctgctgc ggatcctcga
     7321 cctgctggcc ggggcacgca tcgaggcgcg ggtgctgaag ggaacggccg tcgcgcacct
     7381 ggactacccc gatccggcgc tgcggtcgtt caacgacctc gacgtgctgg tgcgggccgg
     7441 ggacatcgac cggacggtcg aggcgctgcg gaccgcgggt ttccagcgca cgctcgccga
     7501 gccgcggccg gggttcgacc ggcggttcga caagggcatg acgttgcgcc cgcccgccgg
     7561 gtacgagctg gacctgcacc gcacgttcgt gctgggccca tgggggcggc gggtcgacct
     7621 ggacgcggtg tgggacgagg ggcaggagtt cacgatcggc ggccgggcgg tgcgggcgtt
     7681 gtcgctgccg aaccggttcc tgcacgcctg ctaccacgcc gccctcggcg actggccgct
     7741 gcggctcggc tcgctgcggg acgtggccga gatgctgcgg gtggtggatc cggggcaggt
     7801 gcggcggctg gccgcgtcgt ggggtgcgga ggcggtggtg gccgccgcgg tggccgacac
     7861 ggtgcggctg ctcggcatca aggtgccggg cgagctggcc cactgggcgg tcgcctacgt
     7921 gccgtctccc cgggacgaat cgtggctggg gttgcacacg acaccggaca agacgttcgc
     7981 cgcgcaggcg gtggcgacgc tgcgggtcct gccgtggcgc gacaagcccg cgtacctgcg
     8041 cgcgctggtc ttcccggacg cgagctacac ggcggaccgg caccgttcgg tgctgagccg
     8101 gttcggctac gccctgcgcg aggtgcggaa gggttcgccc accgggcggc gctgagccgg
     8161 gtcagcgccg cagctcggcg accagcaggt tcgagtcgtt ccccaccagg ttggcgccgt
     8221 tggtcacgta cacccggtgc ccccgcacga cgacggccgt cgtcccctgc atgccgtccg
     8281 cggcgtccag cagggtgtcg tgggaaccgt ccgcgcccac ccgcacgagc tcactcgcct
     8341 ggttgatcgc ggcgaggatc tcgtcgcccc ggccggtgaa gtcgaagtcg tcgatgccgg
     8401 ccagccccgt ggcccggacc tcggcgcggc cgccggtcac cgggatgcgg acgatggtgc
     8461 cccggtcgga gttgctcgcc cacacggcac cgtcgtggat cttcaggccg ttggcgccga
     8521 agaagccgtc cggcgccaga gccgggtcag ccgaccacac cgacgccgcg ccgccccgca
     8581 gcggggcttg ccagatgcgc ccgtcggcgg aatcggtgac gaggacgcgg tcgcggtcga
     8641 tgaccagcgc gttcggcatg gtgtcggcgg gcagcggcac gacgagccga ggctcgccgg
     8701 agcggcccag ccgccagatc ccggtcagcg cgccctgtcc ggcggagtag aggaagtaca
     8761 cgtcgccgct gcccgaccgg gcgaccccgg tgaccacggg ggccccgacg accggggtgg
     8821 tgccgccgcc acctggcggc agcggcatgg tgaccagcac ctggacggcc ccgtccggcg
     8881 cgacccgcac cacctggcgg gccgggatca tgccgatcac cgcgccaccg ccgggttgcg
     8941 gggcgatgct ctcggcggcc tggcccgcgg cgcggtcgaa gtgggcgagc acgcgcacgt
     9001 ccgccaggcg gctggggccc gggtgcgccc gcgcggtggc cggggcgccc gcgacgagca
     9061 gaacggcggc gagcagggcg gcggtccggt gggcggtcat gcttctcctt cggtggtgaa
     9121 ggtctcctgg ccgagcacgg ccagcagctc cagctgcgac accgcggcgc tgcccggcgc
     9181 gggtgagtac acgatcaggc gctggtcctg ccgggccgtc gccaggacgt cgaagtccag
     9241 ttcgatgagc ccgaccgcgg ggtgccggat gcgtttgcgg tcgctgcgac ggaccgccac
     9301 gtcgtgccgg tcccagagcc cggcgaactc cgcgctcgcc gcgcgcaacg cctcgaccag
     9361 ctcgcccgcc gcgcggtcgg ccggccgggc cgcgagggtc gcccgcaggt ccgccacctg
     9421 cgcctggctc tcgtgctcgt ggtcctcggc cggatgacgc tcgcgcatcg ccggatcggt
     9481 gaaccaccgg taggtgcagc tgcgggcgag gccgcggaac cgggtctgct cccccagcag
     9541 cgcgtccgcc atggcgttct gggcgaggac gatgttcagg tcggaggcga tcagggcggg
     9601 caggcccgtc accccgtcca gcagccggag gaggccgcgg ctgacgtgct cgtcaccacc
     9661 ggcgcacggc ggagcgtggt gaccggcgag gcggaacagg tggtcgcgtt cgtcggtcgt
     9721 cagccgcagc gcacgggcca gcgccgcgag caccgtgacc gatggttgcg ggccgcggcc
     9781 ctgttcgacc ctggcgtagt agtccggtga catgccggcg agctgggcca cctcgaagcg
     9841 ccgcagcccc ggcctccggc gtcgcccgcc cgccgggaca ccgacgtccg ccggctggag
     9901 cagcgcccgc cggcgccgga ggaattccgc gagttcgtcc cgtgccacgc ccccagcatg
     9961 atcctctgcc ggcgggacaa ccaggactcg tcgataccac ctaaccgctg gtcgccagcc
    10021 acgcctgctg cagcagcgtc atcgacggcg cgtgcgggct cggcgagagc cagttgtccc
    10081 gcagcgcctc ggcgtccacc agctcagcgt ccaccccgcg accggtccac tcgcgcgcga
    10141 aggcgcgtgt ccgttccgtg aagaccgccc ccgtgaagtc cgccttcgtc gtgcgttcca
    10201 ggacttcgcg gggcagcagg tcgccgaaga cgtcgcgcat cgtggccgtc cggccgctcc
    10261 acccccagaa cccggcggcc cgcgcgatcg ccgccacgaa gtccggctcg gcgaacgtct
    10321 gcacgtaccg gcagtccagt tcggacccca gcgcgcgcac cgtccggtag cccagccgcg
    10381 cgcagcgtcg cgtcgtgaac tgccacgcgt ggcggccggc gtgcagctcg tacgccgccg
    10441 cgtccgccgc gtcccgttcg gcgagcacct cctccgccgc gggccgcagc cacgggcgcc
    10501 ggtaccgggc gcgcagcacg gcccgccgcc gcacggacgc gggcgccagc gcgcgcaccg
    10561 cgtcggtgaa cacccgggcc ggcacccgcc cgcgtgcctt gagcaccttg gtcagcggcg
    10621 tgatccgctt cagcccgaac acctcgtcgc cgccctcgcc ggtcagcagc acgccaccgc
    10681 gagccgcgtc catcatccgc caggtcggcg cgaagttcgg cggccacacc agcccgtgcc
    10741 gccgcagcac cgcggtcgcg atcgggccga ccggatcatg ctcgtcgtcc acggtcagca
    10801 cgatgcgttc ggtgatcccg aggtgcgcga gcacggcgtc ctgccacgcg gattcgtccg
    10861 acccgggcgc cgccgggtag cgcagcgtga tcggcaccgg caggggcagt ccttcgcgcc
    10921 gggccagtga caccgccgcg gccagcagcg cggaggagtc gcggccgccg gaaaaggcga
    10981 ccaggcaggg tgtccgcgtc aggtgcccga gcaggatccg gtcgagcacc cgccgcggct
    11041 cgccgggatc gcccagcggc aacgggacga ggtcgtaccc gttgatccag ccgcccgcga
    11101 tctccagtcg gtccattgtg tacagggcca cggggtgctc actttcggac agtcggcgga
    11161 cggggacagg cggtcacggg accggcggca gcgcgccggc cccgtgaccg gtgaatcgtc
    11221 atgagtacgt gtcgttgtcg ccgagaatcg gcaatgccca cgtgaggttg tccggcgcct
    11281 gaccgaacag gttcgcctgt gtcaagtccg tcaccgaacc caatagggtg atttccgggg
    11341 tcgcatacgg ttcgcgcatg tgttcacctc cccccgctac tggcagggat gggaaaaccg
    11401 gggtcaggaa aacgtcagat ctccgaagag gctaccggca gcgaaatcgg cgtcgagccg
    11461 ggatcccgac gactgaccga gcgtgagctc ggacaacgtg ccgatgtcct cgatgcccgg
    11521 cgcggcgtac tctttcttca tatcgctcct ttccgttact cgtcgacgaa ggagagccga
    11581 aggacctcga ccgggattcg cctgaatgct ccacgccgtt acaaccgctc gccgaatgtg
    11641 ctggtgaagt tgtccaaccg gtaccggaac aattccggga attcgttttc ccggcggtag
    11701 gatccgacgg tggggatcag aagcgtcgcg gccacgccgc ggttgatcac ggccgcggcg
    11761 cgcgaggtcg cggcggccga ccggttcggc accgcaaccg cggcggtcta ccagatcgtc
    11821 ggcgctgtcg gcgcgctcgg cgtcgtcgcg gcgagcaagc tcaccttcga cgcgttgctg
    11881 caaccggatc acgcccgctt cggcctcacc gtttcgttgc tggcactggc gttcacgacc
    11941 gcactgtccg gttcggtcac cgccctgcag acccagcagc accggttgct cggcgaacgc
    12001 gtgtcgcaac gggtctggga ccgcgtgctg gacaccaccg cgcgcgcgga cctggtgacc
    12061 tacgagtccg ccggcttcgc cacgtcgctg gaacgcgtcc agcagaacgc gctgacccgc
    12121 ccgttcgccg tgaccaccgc gctgctcggg ctgaccggga gcctgctcgg ggtcgtcacg
    12181 atgtcggcgg tgctgatcgg ggtcgagccg ctgctggtgc cgatcctgct cgccgccggg
    12241 ctgcccgcgg tgctgctcgc gcggtgggcc agccgcaccg agttcgcgtt cgcccaccgg
    12301 ctcacgccgc tgttccgccg ccgcaactac ctgcggcaac tgctcaccca gcgcccgtac
    12361 gcggccgagc tgcgcgcgtt ccactcgacg aagccgttgc gggcgcggca cggcgagctg
    12421 aacgccggga tcaacggagc gctgcggcag caggtccggc gccgccaggt gatcgccggg
    12481 ctcaccacgg tcggcgtcgc cctgtcgctg accgccgcgc tgctggcgat catcgggctg
    12541 gtgcgcagcg gccggatcga cctgcccgcg gcgggcgccg ccgcgatcgc ggtgcggttg
    12601 ctgagcagcc agctcggcac cttgttcacc tcgatcggcg ggctgctcga atcggcgccg
    12661 ttcctggccg acctggaacg gttcgtcgcg tcggccccgc gttcggcggc cgccggggcg
    12721 aagcggccgt tgcggcaggg cgtcgtgttg cgggacatca gcttccgcta ccccgagcag
    12781 gagcggcccg cggtcgactc ggtggacatc gagatcggcg cgggcgaggt ggtcgcgctg
    12841 gtcggcgaga acggctccgg caagacgacg ctggccaaga tcgtcgccgg gctctacgac
    12901 ccggaccttg gcacgcgccg ctgggacggc acggacgccc cggcggccga catccgcgcg
    12961 tcggtgacgg tgatcttcca ggacttcgtg cgctaccaga tgacgttgcg cgacaacatc
    13021 acgatcagcg acggcgaccg ccccgccgac gaggagtcgg tgcacgacgc ggcccggcgc
    13081 gcgggcgtgc tcggcgtgac gcgcgagctg ccgcacggcc tggacacgat gctcggccgg
    13141 gacctggacg agggtttcga cctctccggc gggcagtggc agcgggtggc gctggcgcgg
    13201 gcgctctacc gggacacgtc gctggtggtg ctggacgaac cggccgcggc gctcgacccg
    13261 cgcgccgagc acgaactgtt caccgacgtc cgggcgatgc tcggcgggcg cgccgcgctg
    13321 ctgatctcgc accgcttctc cagcacccgg atggccgacc ggatctacgt gctcgacgcg
    13381 ggccgcgtgg tggagtgcgg cacgcacgac gagctgatgg cccgcgccgg ccagtacgcc
    13441 gagctgtacc gcctccagtc agcggcctac cgctgagagc aggtccgcga gcacctcgtc
    13501 gcggaagggc gggccccagg gcacggtcgc ctcgaacacc ggcacctgcg ccaccaggtc
    13561 cgccagccgc tggaacgcga agtccatcac cgccggatcc cgccacccca gcacgcgcgg
    13621 gaactggctc atccgcacga acgcccgcgc cccggtgatc cgctccaccg aaacgtccgt
    13681 cgcggaccgg ctcggccgcg ggatcacgca cgcggccagc ggcaacgcgc tggcggacac
    13741 agtggaccgc aaagccagcc ggccgtcggc ggtcggccgc acgtcctccg cggcggcccc
    13801 gtccgccagt ccgcgcgcgg ccatccgcag ccggttctcc gtgctgcccg ggtacacgag
    13861 cgcgccggga tcgacgcgca gcacgtcgtc ggccaccagg tcgcacccgt acccgcacag
    13921 cgccgccgcc aatgtggact tccccatccc cgacgcgccg acgaacgcca gcgcgcggtc
    13981 gtccacccgc accgcgctcg cgtgcaacac caggtgcgag ttcagggtca ggtggatggc
    14041 gagcagcgcg cccgtcgcga gcacggtcag caacccgtga tcggccgacg ggtcgaggtg
    14101 gtaggtcacc tcacgcagcc gcacgtcgcc gacgaactcg cacagcgacg ggtaccgcag
    14161 cacggtccgg tccccgtccg tggcgagtgt gtagaacacc cgcccgtccg gtttcgccag
    14221 ttcggccagg caccggccgg gcagctcggc ccgcggcacc gtccgatcgg aaccgcggcg
    14281 cagcaccaga tccggctcgc cgccgtcacc gggtggcagc gccagttcga catcgctcca
    14341 gacggtcagc ccgtgagcct ggtaggtgaa gtccattgtg gtcaccccgc cgatccgagt
    14401 accgcgtacc gcgccgccat ggggtccatc gccctgccgt cgatctccag ccacgagtgc
    14461 gcggcgaacc ggccgtcctc gcgccgcacg ccgatgcgca gcaccggttc cagctcccgc
    14521 aaccggtgcc cgatcagcag gcactgccgc aggcacgtgt ccccggccgg ccaccgcgac
    14581 accacgaagt acgaggcccg gatcggcgcc cgcgaccacc gcggcagcac cggcgcctcg
    14641 gccgagggcg gctcggtgct ggtgagatcg cagcgcaccc ccagccggcg gcacgtttcc
    14701 cgcaggtccg agcgccgcag gcggaactcg atccgcacca tcggcggaag cgcccgcagc
    14761 acctcccagg ccagccgggc ccgtcgccgc cacctcatgc cgcctccgcc agccaggcct
    14821 gctgcaacag catcgcggtg gacgccggcg gctcgtcggc cagccacgcg gtccgcaacg
    14881 cgtccggatc gaccagcgac gcgtcgacac cgctgccgtc ccagttccgc gcgaactccc
    14941 gcgaccgcgc cccgaagcgg gaggcgttga accgcgcctt gtcccgccgg gtgaggaccg
    15001 cctccggcag cagcccgtcc gcgaccagcc gggtgcccgc cgcgcgggtc atcggtgcga
    15061 cagccgcgta ggacgccacg aacgtcggat cggcgaacgg ttccaccagc tcgcagccgt
    15121 actccgcggc cgcgtcggcc cgcgtccgga atcccaccga gaacgcgcgg gtcgccaacg
    15181 cggtgcgcac gctggtctcc caccgcaacg ggcggtccgc ggccgcgcgc cacagcgtgc
    15241 ggcgcacgtc cggccgcagc cacggcatcg gcagcgaccg gcgcgcgagc cgtcggcggg
    15301 cgaacgcggg cgccgcgcac agcgcgaact gcgcccagtc ggccccggtc atcccccggc
    15361 cacgacggcg cgccaccgcc cgcagcgtcc cgagccggtg cccgccgagc acctcgtccc
    15421 ccgcgttgcc ggtgaccagg ctgccgcccg gcgcgtgcga cgcgagcagc atcgtgttgc
    15481 ccagcgccgc cgggtagacc gggccgcgcg cccgcagcac cggccgcacg agcggtccga
    15541 tcaggtccag ctcgccgtcg atgtcccggc gcgcccaggt gtcgacgccg acgtgccgga
    15601 tcaccgcctc ctgccaggcc gactcgtccg cggccgcgtc accgggatag cggaaggtca
    15661 gcgcgatcgg tggtgcgagc ccctcccgtg cggcgagatc ggccgcgacc gccagcaaca
    15721 ccgacgagtc ccgcccaccg gaaaaggcga tcacacacgg ctcacgcagc aacgccggtc
    15781 gcacggcgtt ccgcagcgcc agcaccgggt ccgtgggcac gccgagcggg aacggcgcga
    15841 caccgagcgg ctgaccggcc gcgatgtcca gtgtggacag ccgcggcggc gcctcagtgg
    15901 aggagctcgg catcgcggag ccggccgagg aaggcctcga tgtcgcggcg cgcggtgtcc
    15961 gcgtcgatct cgtactcgct ggtgatcgcg ccgaccaggt cctcgaccga ccgctcctcg
    16021 gcgagcagct cgaacaaccg cgtgccgaca ccggtgatgg tgaagtactt cgaggtcgac
    16081 aggctgagca cgatcgtctc gtcaccgatg gtgcgagccg agatgtcgga tgcccgtacg
    16141 cgcatggcgg ccctcccgga gctggcggct tctcctgcga gtcgccggcg accgcctccc
    16201 cgttacgccg aaacgaaccc ggccgggaga ccgactccca acggtgaccc gcaccttgct
    16261 gcccgcacga gccgcaatgc ccgccaccgt gcggcgtccc ctgctggtgc tggcgatccc
    16321 cgccgcgatc accgtcgtcg tgctggccgt ccacttcgcc ggcacgcacg ccgcgggcgc
    16381 gctcgaccgc tggatcctcg acgcctcggg cggcgcgatc ccgttcccgt cgcagcaacg
    16441 ggtcacggcc aagggcctgg acttcgcggg cgaaccggcg ggcgccgcgc tgctggtgac
    16501 cgcgctgatc gcgctctgcc tggtgctcgg gcaccggcgc gcggccgtgc tcgcggtgct
    16561 cggccccggt ctgtcggtgg ccgtgacgac gctgctgaaa cccgtcgtgg ggcgcaccat
    16621 caacggcccg cacctgtcct accccagcgg gcacacggcg gtggtgaccg cgatggtcct
    16681 ggtgttcgcg ttcgtcctgg tggaccggct gcggctgcgc acgcccgccg cgacggccgt
    16741 cgtgctctac gccgccgtca ccaccggtgc cgcggaagcg tgggcgcagt acggcatggt
    16801 cgtgcactac ccgacggaca cgctgggcgg cttctgcgtc gcgctcgccg tcgtgcccac
    16861 cacggcctgg ctcgtcgacc gcgtcacgcg tagggccgga acaccggctt gaccgggcgg
    16921 ccaccgatcc acggcgtcgg gtcctcggcg tccagcgcct tgcggtacac ggcacacgcc
    16981 tgggccacca cgtccaccgt ccggtcgatg tcggcctccg tcagtgcgct gctcaccacg
    17041 aacgacggcc cgagcacgcc accggccacc agctggcgca ggaacagcgt ccggtacggc
    17101 tgggacggcc gcagctgctc gtcgagcgtg ccgaacacca ggttgctcgc ccggccccgc
    17161 accacgacgt gctcgccgac gcccatcgcc gccgccacgt cccgcacccc ggacgccagg
    17221 cgctcgccca gcgcgtgcag ccgggccgtg acgccctcct cgacgtaggt gtccatgacg
    17281 gccatcgccg cggccagtga gtgcgtctcc gcgccgtgcg tggtggacag caggaacacc
    17341 cgctcccgcg cgtgccgcag cccgccgagc tccatcagct cccgcttgcc ggccagcgcg
    17401 gacaccgcga acccgttgcc gagcgccttg ccgaacgtgg acaagtccgg cgtcacgccg
    17461 tagtagccct gcgcgcccgc ctccgaccag cggaacccgg tgatcatttc gtcgaagatc
    17521 agcaccacgc cgtaggagtc ggccagcgcg cgcagcccct cgaggtaccc tggcgggggc
    17581 tcgaccgcgg tggcggcctc caggatcagg cacgcgacgt cgtgctgccg caggacctcc
    17641 tcggtcgcgg ccaggtcgcc gtacgggaag cgcacggtca gcgcggcgat ctcgtccggg
    17701 atcccggcgg gcatgccggt ggtgccgatg aaccagtcgt cggtggagaa gaacgggtgg
    17761 tcggcgcaga tcgcgaccac ccgccgcccg gtcgccgcac gcgcgagccg gaccgcggcg
    17821 gtggtgacgt ccgagccgtt cttggcgaac ttgaccatct gcgcggtcgg cacggtcgcc
    17881 aggaacttct ccgcggcggc cagctccacg gtggacggcc gcacgaagtt gctgccccgg
    17941 tccagctcgc gccgcacggc ctcgaccacc cgcgggtgcg cgtgcccgag gctcaccgac
    18001 cgcagcccgg agccgtactc gatgtattcg ttgccgtcca cgtcccacac gtgcgcgccg
    18061 cggccgtgcg agatgaccgg cgccagcccc tccgggtact ggtcctcccc cttggcgtag
    18121 gtgtgcgcgc caccgggcac gagctggtgc agacgctcgt tggcctcggt ggaccggggc
    18181 aggaactgcg cgtccatgac tgtcacctca gggtcttcag aacttcggcg agcgagggcg
    18241 cgcgccggtc gcggtcggag gtcaggctca ccggcagcgg ccacgggatg gccaggtccg
    18301 ggtcgtcgaa cgcgatggtc acgtcttcgg acgggtcgtg cggccggtcg atgcggtagg
    18361 agacgtcggc ggggtcggtc agcgcctgga aaccgtgcgc gcagcccgcc ggcacgtaca
    18421 cgctgacctg ggtgtcgccg gagagctgga agtactcggt gttgcggaag gtcggcgagt
    18481 ccggccgcag gtccacgacg acgtcgaaca cctcgccgta ggagcagcgg accagcttgg
    18541 cctccccggc gccggagcgc aggtgcatcc cgcggatcac gcccttgacc gagcgggaca
    18601 ggctgtcctg cgcgaagccg tccgggtcga tgccgacgga ggcgacgacc tcgcggtcga
    18661 acgtgcgcga gaagaacccg cgcgcgtcgg cgtgcggtgt cggttcgaac aaccacgccc
    18721 cggcgatgcc gggtaccggt acggccttca cgtccggctc ccttcgatga cggactcgga
    18781 catgatgtcg aactggcgct cgagccgctc ggtcatcaca cgattgcgtt ccttgagcac
    18841 cgcggtcagc tcctcgcgcc ggtcctccag ctcgcggaac tgccgcacca gccggtcgaa
    18901 gtcgggttcc cgggcggact ggcagaactc gccgagcccc atcgcctcca tgagcacgtc
    18961 gttcttgcgc gcgtagccca gggaaatcgt cggtttcgcg gtcttcagcg cgcagagcac
    19021 gttgtggtag cgcgtggcga cgacgacgtc gacggcggcc atctggtgca tgaggtcctg
    19081 cagcgaggtc agtggctcgg cgacgatatc cgcgcccggc accgcggcga tgatctccgc
    19141 gggcacctcg gcgtcggcga catcgccggt gaacaaccgg atcgggcggc cctcgtcggc
    19201 cagcaggcgc acgaaccgtt tcacggtggc caggtaggcg cggttgatct cgtccgcgcg
    19261 ggcgcggtcg tcgttgccgc cgtggaaggc catcacgccg accccgaccg cgccggccga
    19321 ggtccgcggt tcgggaccgt cgaggccgaa cgccaggtcc gggaagacgc cgtccccgct
    19381 cacgtcgacc cccatgcggg ccatcgcctg acgcgagtgc tcgtcccggt aggaccggta
    19441 gtgcgccagc cgcgcggcgc gcgtgatgac ccaccgggtg gcgcgtttgc gcaccacgtc
    19501 ggcgccgacg ctgacgagcg cgaccctggt cccggtgagg cgggcggtca cgccgagcca
    19561 gaacagcgag tacggcagcg cccacggccg cagcggcagc gtcgcctcca gcacccccat
    19621 cccgggcacg atgaccacgt cgaagttccg cacccaggcc caggtccgga acgggtcgag
    19681 cagcttgccg agcaccttca acccggccgc ccgcaatccg gtcgcgtcac ccgcgtgcgg
    19741 ctcgtaccac tgcaggtgcg tggcgggcgc gccgtaccgc gcggtgagtt cctccggccc
    19801 catcgccagg aaacccagct cggagtccgg atatcgcttt cgcacgtatc tcaatacggc
    19861 gtcgagcgat ccgtcgttgc ccaggttgcc cgagccgagg atgccgaaga acccgatgcg
    19921 cgtcacgaaa gcagacccac cttccgcagt ggcttgccgc cgagccattc cgcgatcacg
    19981 gcgtagcagc ggcgccgttc gctcgacgac agcggtgcgc gccggatcgc cgtgacgtac
    20041 ccggccaggt actcggcgaa cagccgcgcc ttcgactggc cctcccggcg cgggtcgagg
    20101 ttcgcgcaca ccttctgcac cgagcccagg ttgtcgccgc ggcctgggtg ctcgcggcgg
    20161 aagaacatga cctccgggac ctgcacgaac gtcccgtgca gcgcgagttc accgaccagc
    20221 ttgcggccgg cgttgtggta gctgtcgtgc ggtgcgatcc gccgcatcac cgaggtgcgg
    20281 atgacgccgt agaagtcgtc cccgccttcg gtgaacatca ggctgcggaa ccggaccgcg
    20341 gcgtccggcg aatcggtggc caggccgtag tcgtagttct cgatgacctc gccccgctcg
    20401 tccacgatcg ccatgtacgt gtgcgcgagc accgcttccg ggtgctcgtc gagcgcctgg
    20461 acgcagcgcg ccagcagctc gggggcgaac aggtcgtcgt gcgcggccca cttgaagaac
    20521 tcgccgcgcg ccgcccgcac cacgaagttg tggttgggcg cggccccgat gttgcgcggc
    20581 tgccgcacgt accggatgcg gtcgtcccgc gcggcgtact tctcgcagat ctcctgcgtg
    20641 ccgtcgccgg aggcgttgtc cgagatgatc agttcgaagt cggtgaaggt ctgggccagg
    20701 aggttgtcga gcgcctcggc cacgtagttt tccccgttgt agacgggcag tccgatgctc
    20761 aacctcggtg cggtcatggg gtcctcgatt cctccgggac agggacgtgt gcgcgggcgg
    20821 cgacgtgcag ctggctccac cacacgaacg cgcccgcgaa ggtggcgcac gcgacgcccc
    20881 agccggaccc cacggccccg ccgatcgccg cgccggacag gccgccgatg acgtagaggg
    20941 acgacgcgat gagctggcag cgcatgctgc ggcgggccgc gcccagcgcc cgcaggccgg
    21001 tcgcggcgcc accgatgaag ctcgcgttga agacggacag cgtggcgggg atgatcatcg
    21061 cctgggcggt gcgccagacg tcgccgagca cgagctcgcc gaggtggtcg ttcaggacga
    21121 gcagcagcgc gccgccccac agcagcgcag cgagcgcctg gctcccgccc agcaccaggc
    21181 agaaggtcgt cagccgccgc acgttgcggc gcaccacgcg ggccgcctcg ggcaccgcga
    21241 cgtaggccag gcccatcagg accgcgagga acgggccgag cagcagttcg ccaccccgca
    21301 cggtcccgac ggccgccagt ccggcgatgg cgccgaggcc gtacatccgg atctgcgaac
    21361 caccgctgtt gctgacgttc tcgacgaggt agcgcggccc gaggtcgcgc tggtcgcgca
    21421 gccaggaccg caccccgtcg aggctcggcc gcagaccggt ctgcaggtag ccgtagcccg
    21481 cggcgaccgc ggccgcgcca ccccaggcca gcaggaacgc gacgacgctg ccgtgcagcg
    21541 cggccagcac catcgccggg atcatggcca cgccccacag ggcgtcgttg acgaacgact
    21601 tctggccttc gccggaggcg aagaacgcga accgccagct gtcctgcaac agcagcggcg
    21661 gcaggatcac gccgagcgcg acgaacgccg gtccgacgct cccgcccacc acgattccga
    21721 acagcacgct gaccaggccc gccacggcgc ccacggccag tgcggtcgcc gacgaccggg
    21781 ccaccgccgc acgccacaca ccggtgtcga cgccgctgaa gcgcaccatc agcgggtcgg
    21841 tcgccagccc gcgcgagacg ttgagcatga caccgtaggt gacccacgcc aggctgaaga
    21901 cgccgaacgc ggtgacgccc agttcgcggg ccacgtagat gccgacggcg aagttcgtca
    21961 ggctcgacac cgcctggtcg cccagccccc aggacaaccg cccggccatg gctcgcagcc
    22021 cggacggctt cgcagcgggc ttgcggtggc ggcccgtggt catgggatca cccctccacc
    22081 agtgcgtgca tcccgggccc gcaacgcatc acacgaaccg cagggtgtcg tcgaccgcac
    22141 cggcctcgcg gtgccgcttg agccgcgcga gccgggtgaa gctccgctcg aacgcggagt
    22201 gggtcagccc gtgccgctgg taggcctcga ccagctcgac cgcgccgtcc ttgaccgacc
    22261 actcgcaggt gaagccgggg atcgcggcgc ggaagcggga gaagtcgacc cggtaggacc
    22321 gcgggtcggc gccggcctcg ccggtgatcc gcagccgaga gcccggcacg gcctcgacga
    22381 cctgctcggc gatctcggcg acggtcacgt tgttgcgctc ggttccgatg ttgaacgcct
    22441 tgtcgtgcac cgcttcgcgc ggcgcgacca gcgcggcggc gaacgcccgc gcgatgtccc
    22501 gcgcgtgcac cagcggccgc cacggcgtgc cgtcggagag caccagcacc tcaccggaca
    22561 ggcacgcgtg cccgaccagg ttgttcagca cgatgtccgc ccgcagccgc ggcgagaacc
    22621 cgaacgcggt ggcgttgcgc aggtagaccg gggtgaagtc gtcatcggcc agctcgtgca
    22681 ggtcgtcctc gacgagcacc ttcgactccg cgtacggcgt caccggccgc agcggagcgt
    22741 cctcgttgac caggtccgcg ccgcccgaag cgccgtacac cgagcaggtg gacgcgtaga
    22801 ggaaccggga caccccggcg tccttggcca gccgcgccag ccggaccgcg gccctgtggt
    22861 tgatctcgta ggtcagctcg ggcgccagcg cgcccagcgg gtcgttggac agcgccgcca
    22921 ggtggatcac ggcgtccaca ccggacacgt gctcgggtgt gacgtcccgc aggtccaccc
    22981 ggtgcccggg cgggtcctgc ggcttcgggc cgagcacgca ctcgtcgaac agaccggagt
    23041 cgagcccggt cacctcgtgc ccggcggcgg tgagcaccgg cgccatcacc gtgcccagat
    23101 accccttgtg cccggtcagc agcacacgca tggctcaacc ctccagctgg agacacaact
    23161 tccggaccgc gaaggcctcc gcgtaccgcg cctggcattc gatcccccga atgcgggcca
    23221 gcccgaggaa agcctcccgg tcgtaccaag gacgatgtcg ctgcgagggg tagtgccgtt
    23281 gcagcaattc gacttttttc tcggcgagtt cgtcacgcag cggcacgtac accgacggtg
    23341 tgcccaggtc gccgtcccac ttgacgatct cgtagccgag cgtgaggtgc ccgcggaacg
    23401 cggtcggcac cagcttggcg aggccgcggt ggtcctggtg cgcgtcgtcg gtgcgcggtg
    23461 cgacgatcag gtccgggtcg gtgcgcgccc gcagttcctc cagcgcgttc ttgacctcgt
    23521 cccagtgcgc gggcagccgg ccgtccggca tcttcagcac ggtcacgtcc aggtcggcgc
    23581 ccgggcagaa cgccgcgagc gccgcgcgtt cctcgtcctc gcgctcactg ccgccgccgg
    23641 agagcaccag ggcgtccacc cgcagtccgg gacggctcag cgtgagcagg gtgccgcccg
    23701 cgccgatcgc gatgtcgtcg cagtgggcgc cgagcaccac gatccgctcg agccgctccg
    23761 gaatcagtcc gatcacgccg gcactcggtc cttctcccac agcgcccacg ggcgcacccc
    23821 gcgcgtgtag gcctcgtcca gggcgtagcg ctccttgacc gtgtccgtcg gcttccagaa
    23881 gccgcggtag gggtaggcga gcaggcggcc gcgcttggcg agttcggcgc acccgtcggc
    23941 gaccaggtcg ccgttctccg ggatgtggtc gaacacctcc tggcgcagca cgaagtaccc
    24001 gccgttctcc cacaacggca tctcgctcac cgcggtgatg gagccgacca ggccgccctc
    24061 gtccatctcc acgcagtgga acgacgactg cggcggcacg accatcatcg acgcgcccgc
    24121 gtccgaccgg gagaaccgtt cgatcatcga cggcagcggc gcgtcggtga gcacgtcggc
    24181 gtagttggcg aggaacatct cgtcaccgtc gaggtgcttg cgcacgcggc gcagccgttc
    24241 cccgatcggc gactcgatcc cggtctgcac gaacgagatc gtccagtccg cgatgtcggt
    24301 ggacagcagc tccgccttgc cgccgcgcag cacgaagtcg ttggaggtgg tctcctcgta
    24361 gttgaggaag aagtccttga tgtggtgggc gccgtaaccg aggcacagga tgaactcggt
    24421 gtgcccgaag tgcgcgtagt agcgcatcac gtgccagatc agcggccggg gaccgaccat
    24481 cgccatgggc ttgggcacgt cggaagcggt gccgttgcgc atccgcatcc cgtacccgcc
    24541 gcagaacagg acgaccttca cgttggattc acctcgacga tttccaggcg gggtatgggg
    24601 aagaccagct tgccgcccca ctccccgacg taggacagct gctgggtcag ttcgtcccgc
    24661 aggttccagg gcaggaccag gacgtagtcg ggccggtccg cggcgatgcg gtccggcggc
    24721 aggatcggga cgcgcgtgcc cggcgtgaac cggccgtgct tgtacgggtt gcggtcgacc
    24781 gtgtaggcga gcaggtccgg ccggatgccg cagtggttga gcagggtgtt gcccttgccc
    24841 ggcgcgccgt agccgaccac ggtgaggccg tcgtcggccg cgtccacgag gaaccgcagc
    24901 aggtcgcggc gcacgcgggc gacccgggcg gcgaactcgg tgtagccgga gagttcgtgc
    24961 agcccggcgg ccttctcccg ggccaggacg tcgaccatgc ggtggctcgg ttcaccggcg
    25021 gtttcggcgg gctgggccca cagccggatg gagccgccgt gggtcggcag cagctcgacg
    25081 tccactaggg acagtccgcc ggaggcgagc gcccgctgcg ccgaagccac cgtgtagtac
    25141 tggaagtgct cgtggtagat cgtgtcgtac tgggtcttct cgatgagcgt gagcaggtgc
    25201 tgcacctcga tcgacaccca gccgtcgtcg gcgaccagcg cgcgcaggcc cttcgtgaag
    25261 ccgatgacgt ccgggatgtg cgcgtagacg ttgttcgcca cgaccagatc cgcgggaccg
    25321 tgctcggccc gcaccgccgc gccggtctcc gggccgagga acgcggtcag cgtgggcacg
    25381 cccgcgtccc gggcggcttg gccgacgttc accgacggct ccacgccgag gcagcggatg
    25441 ccctgtgcca caacgtgttt gagcaggtac ccgtcgttgc tggcgacctc gacgacgaac
    25501 gagtcgccgt ccaggcccag ccggtccacc gcaccggcga cgaaccggcc cgcgtgatcc
    25561 acccaggatt ccgaatacga cgagaaatac gcgtattcgg tgaacgtttc ctcaggagtg
    25621 atcaacggcg ggatctgcgc gagccagcag tccgtgcaca cccgcaggtg caacggaaag
    25681 gtattttccg actcgtccag ttgtgcttcg gtcaggaacg cctcgcacgg cggggtcgcc
    25741 ccgaggtcga cgacgctggc cagctgtgtc gagccacaga gtcggcagga ggtcatgctc
    25801 ctgattcggg agacgcgaag gacctgttac aaacacgcgg ccggttcgtc ccaccgtctt
    25861 cgaaatgaga ccctatttgc ggatctccag cgtgcagcac ttcggcccgc caccggcctt
    25921 gcgcagctcg gaaatgtcca cgggcaccgg ttcgtagccg cgggccgcga gccgctcggc
    25981 caagtccgtg gcctccaccg gcagcaccac gttgcgcccg tcggacacgc cgttgaggcc
    26041 gaagcactcc gcgtcggccg ccgtcgcgag cacggcgtcg gggaacaggc gcgccaggac
    26101 gcggcgcgag ccggccgaga acgcctccgg gtagtaggcg atctg
//
