LOCUS       NZ_BMWB01000057         7083 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces xantholiticus strain JCM 4863 sequence57, whole genome
            shotgun sequence.
ACCESSION   NZ_BMWB01000057
VERSION     NZ_BMWB01000057.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces xantholiticus
  ORGANISM  Streptomyces xantholiticus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 7083)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 114X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014651015.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:24:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,091
            CDSs (total)                      :: 7,016
            Genes (coding)                    :: 6,693
            CDSs (with protein)               :: 6,693
            Genes (RNA)                       :: 75
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 323
            CDSs (without protein)            :: 323
            Pseudo Genes (ambiguous residues) :: 0 of 323
            Pseudo Genes (frameshifted)       :: 187 of 323
            Pseudo Genes (incomplete)         :: 270 of 323
            Pseudo Genes (internal stop)      :: 13 of 323
            Pseudo Genes (multiple problems)  :: 140 of 323
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:39:19
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 7083
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMWB01000057.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     gene            <1..2798
                     /locus_tag="IE198_RS34535"
     source          1..7083
                     /culture_collection="JCM:4863"
                     /db_xref="taxon:68285"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces xantholiticus"
                     /strain="JCM 4863"
                     /submitter_seqid="sequence57"
                     /type_material="type strain of Streptomyces xantholiticus"
     region          1..7083
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..7083
                     /SMILES="C(CC)C(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..7083
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[2819:6218](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2820..6218
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     CDS             <5..2798
                     /NRPS_PKS="Domain: PKS_DH (17-187). E-value: 3.9e-54.
                     Score: 175.4. Matches aSDomain:
                     nrpspksdomains_IE198_RS34535_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (474-654). E-value: 1.1e-60.
                     Score: 196.7. Matches aSDomain:
                     nrpspksdomains_IE198_RS34535_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (752-838). E-value: 1.1e-27.
                     Score: 88.2. Matches aSDomain:
                     nrpspksdomains_IE198_RS34535_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (860-927). E-value:
                     1.1e-09. Score: 31.0. Matches aSDomain:
                     nrpspksdomains_IE198_RS34535_PKS_Docking_Cterm.1"
                     /codon_start=3
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF020243.5"
                     /locus_tag="IE198_RS34535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I polyketide synthase"
                     /protein_id="WP_189894002.1"
                     /sec_met_domain="adh_short (E-value: 1.6e-65, bitscore:
                     208.0, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-14, bitscore:
                     42.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VPAGRGDVAGLGLAAAGHPLLGAVVSLPDGRGTLWTGRLSLAEQP
                     WLADHTLHGSVVVPGAVLVELALQAGHQMRCRHLGELTYHRPLLLSSEGVSLQLLVAEA
                     DDDGRSTVEVFARPGDAANDTEWTLHASGELIRTAGTAKHEGALGDVRPGPWPPAGATA
                     QPVDEVYERTARSGVGLGPVFQGLRAVWRRGDETYAEVALPEPMSESAAAYNMHPALLD
                     AVARVAAEGGAAEAELASAWSGVESFAVGGSSVRVSVVPSADGEVSIAVADDTGAPVLS
                     VARLATRQVMQKELRSADRALRDALFDVEWTRVQGSCAPPTGWSEWGSPEEGPAVPELL
                     VLPHSGEADPTAATARALTVLRDFLSDERFVDTRLVVLTRGAVGTRPKEGIADLAAAPV
                     WGLVRSAQAEHPDRLVLVDVEPGLDAVAEAAALRIALGTAEPQVAVRGGKALLPRLVRT
                     KGPSELRDERPGFGPQGTVLVTGGTGGLGALVARHLVSAYGVRELLLVSRRGSAAEGVD
                     ELIAGLEESGARVRVEACDVSDRAALAALLAALPEDRPLTGVVHCAGVIDDGVIESLDE
                     ERLARVFRPKVDAALHLHELTADLGLSAFVLFSSVAGVFGAAGRANYAAANTFLDALAY
                     ERRAQGLTAVSAAWGLWEEDRGMGGHVTGADLARIRREGAVAMSAEEGLALFDAVLAHD
                     RELCVPARLDLASIAGAGSPPPPVLRQLVPPARRHLDAQGAFRQDDAPVNTAEKLAGNL
                     AGLTEAEQMRTLLGLVRGHVATVLGHADLEAVSPDRGFLDSGFSSVAVVELRNRLSRST
                     GLRFSAVTLFDHPTPRAVARHLRERLAPDSVTGNGPAVTGAELGRTDAADFRAALSAVP
                     LARLKEVGVLDALLRLTGFDGEPDGRAGAADPTAVTPMTPESIDAMDLDSLVDMAINTD
                     L"
     aSDomain        57..566
                     /ASF="catalytic triad H,G,P found: False"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34535_PKS_DH.1"
                     /evalue="3.90E-54"
                     /label="IE198_RS34535_PKS_DH.1"
                     /locus_tag="IE198_RS34535"
                     /protein_end="187"
                     /protein_start="17"
                     /score="175.4"
                     /tool="antismash"
                     /translation="HPLLGAVVSLPDGRGTLWTGRLSLAEQPWLADHTLHGSVVVPGAV
                     LVELALQAGHQMRCRHLGELTYHRPLLLSSEGVSLQLLVAEADDDGRSTVEVFARPGDA
                     ANDTEWTLHASGELIRTAGTAKHEGALGDVRPGPWPPAGATAQPVDEVYERTARSGVGL
                     GPVFQGL"
     aSModule        57..2519
                     /domains="nrpspksdomains_IE198_RS34535_PKS_DH.1"
                     /domains="nrpspksdomains_IE198_RS34535_PKS_KR.1"
                     /domains="nrpspksdomains_IE198_RS34535_PKS_PP.1"
                     /incomplete
                     /locus_tags="IE198_RS34535"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       141..218
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34535_0001"
                     /evalue="2.00E-10"
                     /label="PKSI-DH_m2"
                     /locus_tag="IE198_RS34535"
                     /protein_end="71"
                     /protein_start="45"
                     /score="33.1"
                     /tool="antismash"
                     /translation="WLADHTLHGSVVVPGAVLVELALQAG"
     aSDomain        1428..1967
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34535_PKS_KR.1"
                     /evalue="1.10E-60"
                     /label="IE198_RS34535_PKS_KR.1"
                     /locus_tag="IE198_RS34535"
                     /protein_end="654"
                     /protein_start="474"
                     /score="196.7"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GTVLVTGGTGGLGALVARHLVSAYGVRELLLVSRRGSAAEGVDEL
                     IAGLEESGARVRVEACDVSDRAALAALLAALPEDRPLTGVVHCAGVIDDGVIESLDEER
                     LARVFRPKVDAALHLHELTADLGLSAFVLFSSVAGVFGAAGRANYAAANTFLDALAYER
                     RAQGLTAVSAAWGLWEE"
     CDS_motif       1431..1532
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34535_0002"
                     /evalue="5.20E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE198_RS34535"
                     /protein_end="509"
                     /protein_start="475"
                     /score="28.7"
                     /tool="antismash"
                     /translation="TVLVTGGTGGLGALVARHLVSAYGVRELLLVSRR"
     CDS_motif       1815..1919
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34535_0003"
                     /evalue="1.60E-17"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE198_RS34535"
                     /protein_end="638"
                     /protein_start="603"
                     /score="56.0"
                     /tool="antismash"
                     /translation="AFVLFSSVAGVFGAAGRANYAAANTFLDALAYERR"
     aSDomain        2262..2519
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34535_PKS_PP.1"
                     /evalue="1.10E-27"
                     /label="IE198_RS34535_PKS_PP.1"
                     /locus_tag="IE198_RS34535"
                     /protein_end="838"
                     /protein_start="752"
                     /score="88.2"
                     /tool="antismash"
                     /translation="LAGLTEAEQMRTLLGLVRGHVATVLGHADLEAVSPDRGFLDSGFS
                     SVAVVELRNRLSRSTGLRFSAVTLFDHPTPRAVARHLRERL"
     aSDomain        2586..2786
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34535_PKS_Docking_Cterm.
                     1"
                     /evalue="1.10E-09"
                     /label="IE198_RS34535_PKS_Docking_Cterm.1"
                     /locus_tag="IE198_RS34535"
                     /protein_end="927"
                     /protein_start="860"
                     /score="31.0"
                     /tool="antismash"
                     /translation="ADFRAALSAVPLARLKEVGVLDALLRLTGFDGEPDGRAGAADPTA
                     VTPMTPESIDAMDLDSLVDMAI"
     gene            2820..6218
                     /locus_tag="IE198_RS34540"
                     /old_locus_tag="GCM10010381_70180"
     CDS             2820..6218
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (36-462). E-value:
                     2.2e-181. Score: 595.3. Matches aSDomain:
                     nrpspksdomains_IE198_RS34540_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (568-866). E-value: 4e-102.
                     Score: 333.5. Matches aSDomain:
                     nrpspksdomains_IE198_RS34540_PKS_AT.1"
                     /NRPS_PKS="Domain: ACP (971-1042). E-value: 3.1e-33. Score:
                     105.9. Matches aSDomain:
                     nrpspksdomains_IE198_RS34540_ACP.1"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (1059-1131). E-value:
                     4.1e-12. Score: 38.8. Matches aSDomain:
                     nrpspksdomains_IE198_RS34540_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019984104.1"
                     /locus_tag="IE198_RS34540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_70180"
                     /product="type I polyketide synthase"
                     /protein_id="WP_189894004.1"
                     /sec_met_domain="mod_KS (E-value: 3e-224, bitscore: 732.2,
                     seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 4.1e-95, bitscore:
                     305.8, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2e-103, bitscore: 333.5,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.1e-17, bitscore:
                     51.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTTDDRVVQALRASIKETERLKQQHQQLVESLNEPIAIIGMACR
                     FPGGVVSPEDLWQLVVDGGDAIGPFPDDRGWDLEALYDPEQRRKGTLYVREGGFVEGAA
                     DFDAAFFGVSPREATAMDPQQRLLLETGWESFERAGIDPTGLRGSDVGVFSGTNIQDYQ
                     SLLLTSPGAFEGHVGTGNAAAVLSGRLAYTFGFEGPAVTVDTACSSSLVALHLAAQALR
                     QRECSLALAGGVTLMSTPMGFVEYSGQRVLARDGRCKSFAGSADGTGFSEGVGMFLLER
                     LSDARRNGRRIQGLIRGSAVNQDGASSNLTAPNGRAQQRVILQALANAQVSSDQVDVLE
                     AHGTGTELGDPIEAEALLATYGKDRTPERPLWLGSVKSNIGHTQAAAGLAGVIKMVLAM
                     QHGLVPRTVHVDEPSPHVDWESGTVRLATEPVAWPENGRPRRAGVSSFGISGTNAHVIV
                     EQAPPDPAAIEPAARTAEPDGPFAWTVSGRSDQALRAQAERLAAHLRDRPQLSAADVAV
                     STAGRTAFEHRAVVVGGDLADLEAGLAALAAGREDARLVKGVTIPSGQTVFVFPGQGSH
                     WPEMAGRLLESSAVFRESIDECAEALSAYVDWSLTDVLRQEPGAPSLDRLDVVQPVLFS
                     MMVALAEVWRAHGVEPDAVIGHSQGEIAAACVAGALSLQDAARIVTLRSVLLNRLTGKG
                     AMASFLLSADEVARRIEPYGDRLSIAAVNGPTSVVVSGEPEAVGELVATCLAERVRARK
                     VPGATAAGHSAQVDALRGEFIEGIASVCPRRAIVPFYSTVAGEVVDTATLDATYWYRNL
                     REPVLLEGTVRRLLADEHRYFIEISPHPVLTVGLQETFEQAGTAATAVGTLRRDEGVEA
                     RFLTSAAEAYVRGLPLDLGRLPQLSGARRADLPTYAFQRRRFWPDERIAAAAAVPLRDG
                     AMATADATRAGHDDPSAVNDPGQVLRRLAELPHEEHDAFLVDLVCEQAAAVLGHGSAAE
                     MEPARPFQELGFDSLTAVELRNRLGAALDLALPVTLVFDHPTPRDLADHLASQVEGTLP
                     GPGSATRSEAIGHLEKLEAVLAELGADPGENKEIGLRLQRILTEWTQAREAANDAVGEA
                     EVSSELQGASDEEMFDLIGKKFGIS"
     aSDomain        2928..4205
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34540_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="2.20E-181"
                     /label="IE198_RS34540_PKS_KS.1"
                     /locus_tag="IE198_RS34540"
                     /protein_end="462"
                     /protein_start="36"
                     /score="595.3"
                     /tool="antismash"
                     /translation="IAIIGMACRFPGGVVSPEDLWQLVVDGGDAIGPFPDDRGWDLEAL
                     YDPEQRRKGTLYVREGGFVEGAADFDAAFFGVSPREATAMDPQQRLLLETGWESFERAG
                     IDPTGLRGSDVGVFSGTNIQDYQSLLLTSPGAFEGHVGTGNAAAVLSGRLAYTFGFEGP
                     AVTVDTACSSSLVALHLAAQALRQRECSLALAGGVTLMSTPMGFVEYSGQRVLARDGRC
                     KSFAGSADGTGFSEGVGMFLLERLSDARRNGRRIQGLIRGSAVNQDGASSNLTAPNGRA
                     QQRVILQALANAQVSSDQVDVLEAHGTGTELGDPIEAEALLATYGKDRTPERPLWLGSV
                     KSNIGHTQAAAGLAGVIKMVLAMQHGLVPRTVHVDEPSPHVDWESGTVRLATEPVAWPE
                     NGRPRRAGVSSFGISGTNAHVIVEQAP"
     aSModule        2928..5945
                     /complete
                     /domains="nrpspksdomains_IE198_RS34540_PKS_KS.1"
                     /domains="nrpspksdomains_IE198_RS34540_PKS_AT.1"
                     /domains="nrpspksdomains_IE198_RS34540_ACP.1"
                     /locus_tags="IE198_RS34540"
                     /monomer_pairings="emal -> emal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       3327..3392
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34540_0001"
                     /evalue="1.00E+01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="IE198_RS34540"
                     /protein_end="191"
                     /protein_start="169"
                     /score="-0.6"
                     /tool="antismash"
                     /translation="PGAFEGHVGTGNAAAVLSGRLA"
     CDS_motif       3411..3458
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34540_0002"
                     /evalue="5.20E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE198_RS34540"
                     /protein_end="213"
                     /protein_start="197"
                     /score="21.4"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     CDS_motif       3834..3878
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34540_0003"
                     /evalue="3.80E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE198_RS34540"
                     /protein_end="353"
                     /protein_start="338"
                     /score="12.7"
                     /tool="antismash"
                     /translation="LEAHGTGTELGDPIE"
     CDS_motif       3939..3983
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34540_0004"
                     /evalue="3.80E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE198_RS34540"
                     /protein_end="388"
                     /protein_start="373"
                     /score="12.7"
                     /tool="antismash"
                     /translation="GSVKSNIGHTQAAAG"
     CDS_motif       4518..4574
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34540_0005"
                     /evalue="3.00E-07"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE198_RS34540"
                     /protein_end="585"
                     /protein_start="566"
                     /score="22.5"
                     /tool="antismash"
                     /translation="VFVFPGQGSHWPEMAGRLL"
     aSDomain        4524..5417
                     /ASF="Neither malonyl-CoA or methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34540_PKS_AT.1"
                     /evalue="4.00E-102"
                     /label="IE198_RS34540_PKS_AT.1"
                     /locus_tag="IE198_RS34540"
                     /protein_end="866"
                     /protein_start="568"
                     /score="333.5"
                     /specificity="substrate consensus: emal"
                     /specificity="PKS signature: Methoxymalonyl-CoA"
                     /specificity="Minowa: emal"
                     /tool="antismash"
                     /translation="VFPGQGSHWPEMAGRLLESSAVFRESIDECAEALSAYVDWSLTDV
                     LRQEPGAPSLDRLDVVQPVLFSMMVALAEVWRAHGVEPDAVIGHSQGEIAAACVAGALS
                     LQDAARIVTLRSVLLNRLTGKGAMASFLLSADEVARRIEPYGDRLSIAAVNGPTSVVVS
                     GEPEAVGELVATCLAERVRARKVPGATAAGHSAQVDALRGEFIEGIASVCPRRAIVPFY
                     STVAGEVVDTATLDATYWYRNLREPVLLEGTVRRLLADEHRYFIEISPHPVLTVGLQET
                     FEQAGTAATAVGTLRRD"
     CDS_motif       4686..4757
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34540_0006"
                     /evalue="8.20E-10"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="IE198_RS34540"
                     /protein_end="646"
                     /protein_start="622"
                     /score="30.8"
                     /tool="antismash"
                     /translation="LDRLDVVQPVLFSMMVALAEVWRA"
     CDS_motif       4761..4871
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34540_0007"
                     /evalue="1.40E-20"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="IE198_RS34540"
                     /protein_end="684"
                     /protein_start="647"
                     /score="65.0"
                     /tool="antismash"
                     /translation="GVEPDAVIGHSQGEIAAACVAGALSLQDAARIVTLRS"
     CDS_motif       4977..5015
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34540_0008"
                     /evalue="5.00E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE198_RS34540"
                     /protein_end="732"
                     /protein_start="719"
                     /score="13.3"
                     /tool="antismash"
                     /translation="AAVNGPTSVVVSG"
     CDS_motif       5226..5270
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34540_0009"
                     /evalue="4.30E-05"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="IE198_RS34540"
                     /protein_end="817"
                     /protein_start="802"
                     /score="15.7"
                     /tool="antismash"
                     /translation="LDATYWYRNLREPVL"
     CDS_motif       5316..5345
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34540_0010"
                     /evalue="3.50E-03"
                     /label="PKSI-AT-mM_m9"
                     /locus_tag="IE198_RS34540"
                     /protein_end="842"
                     /protein_start="832"
                     /score="10.0"
                     /tool="antismash"
                     /translation="FIEISPHPVL"
     aSDomain        5733..5945
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34540_ACP.1"
                     /evalue="3.10E-33"
                     /label="IE198_RS34540_ACP.1"
                     /locus_tag="IE198_RS34540"
                     /protein_end="1042"
                     /protein_start="971"
                     /score="105.9"
                     /tool="antismash"
                     /translation="DLVCEQAAAVLGHGSAAEMEPARPFQELGFDSLTAVELRNRLGAA
                     LDLALPVTLVFDHPTPRDLADHLASQ"
     aSDomain        5997..6212
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34540_PKS_Docking_Cterm.
                     1"
                     /evalue="4.10E-12"
                     /label="IE198_RS34540_PKS_Docking_Cterm.1"
                     /locus_tag="IE198_RS34540"
                     /protein_end="1131"
                     /protein_start="1059"
                     /score="38.8"
                     /tool="antismash"
                     /translation="GHLEKLEAVLAELGADPGENKEIGLRLQRILTEWTQAREAANDAV
                     GEAEVSSELQGASDEEMFDLIGKKFGI"
     gene            6276..>7083
                     /locus_tag="IE198_RS34545"
     CDS             6276..>7083
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (3-29). E-value:
                     2.5e-10. Score: 31.7. Matches aSDomain:
                     nrpspksdomains_IE198_RS34545_PKS_Docking_Nterm.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (35-269). E-value:
                     1.5e-89. Score: 292.7. Matches aSDomain:
                     nrpspksdomains_IE198_RS34545_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014174582.1"
                     /locus_tag="IE198_RS34545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="beta-ketoacyl synthase N-terminal-like
                     domain-containing protein"
                     /protein_id="WP_189894006.1"
                     /sec_met_domain="mod_KS (E-value: 1.8e-107, bitscore:
                     347.4, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 2.7e-81, bitscore:
                     260.5, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADEDKLRYYLKRMAAELEATQEQLREATAMRSEPVAIVGMACRY
                     PGGADTPERLWELLAAGEDAVGKFPDDRGWNAGPTDGPYAAEGGFLYDAAEFDAGFFGI
                     SPREALAMDPQQRLLLEVSWEAIERSGIDPKSLKGTQTGAFLSTSYQEYLARLQQTGAA
                     VDAFKLSGNCVSVASGRVSYVLGLSGPAVTLDTACSSALVAVHLAADSLRRGESTLALA
                     GAATVMATEGMFVEFDRQGGLSADGRCKAFGAGADGTGWSEGVGVLV"
     aSDomain        6285..6362
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34545_PKS_Docking_Nterm.
                     1"
                     /evalue="2.50E-10"
                     /label="IE198_RS34545_PKS_Docking_Nterm.1"
                     /locus_tag="IE198_RS34545"
                     /protein_end="29"
                     /protein_start="3"
                     /score="31.7"
                     /tool="antismash"
                     /translation="EDKLRYYLKRMAAELEATQEQLREAT"
     aSDomain        6381..7082
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34545_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="1.50E-89"
                     /label="IE198_RS34545_PKS_KS.1"
                     /locus_tag="IE198_RS34545"
                     /protein_end="269"
                     /protein_start="35"
                     /score="292.7"
                     /tool="antismash"
                     /translation="VAIVGMACRYPGGADTPERLWELLAAGEDAVGKFPDDRGWNAGPT
                     DGPYAAEGGFLYDAAEFDAGFFGISPREALAMDPQQRLLLEVSWEAIERSGIDPKSLKG
                     TQTGAFLSTSYQEYLARLQQTGAAVDAFKLSGNCVSVASGRVSYVLGLSGPAVTLDTAC
                     SSALVAVHLAADSLRRGESTLALAGAATVMATEGMFVEFDRQGGLSADGRCKAFGAGAD
                     GTGWSEGVGVLV"
     CDS_motif       6612..6638
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34545_0001"
                     /evalue="2.70E-03"
                     /label="PKSI-KS_m2"
                     /locus_tag="IE198_RS34545"
                     /protein_end="121"
                     /protein_start="112"
                     /score="10.4"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     CDS_motif       6840..6887
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34545_0002"
                     /evalue="1.50E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE198_RS34545"
                     /protein_end="204"
                     /protein_start="188"
                     /score="20.1"
                     /tool="antismash"
                     /translation="GPAVTLDTACSSALVA"
ORIGIN
        1 acgtcccggc ggggcgcggt gacgtggcgg gcctgggtct ggcggccgcc gggcatccgc
       61 tgctgggtgc ggtggtgtcg ctgccggacg gacgcggcac cctgtggacc gggcggttgt
      121 ccctggcgga gcagccgtgg ctcgccgacc acacgctgca cggctccgtg gtggtacccg
      181 gagccgtcct ggtcgaactc gccctccaag ccggccatca gatgcgctgc cggcatctcg
      241 gggagctgac ctatcaccgg cccctgctgc tgtcgtccga aggtgtctcc ctccagctcc
      301 tggtggcgga ggcggacgac gacggcagga gcacggtgga agtcttcgca cggcccggcg
      361 acgcggccaa cgatacggaa tggaccctgc acgcgtccgg cgagctgatt cggaccgccg
      421 gtacggcgaa gcacgaaggc gccctcggcg acgtacgccc cggcccctgg ccgcccgccg
      481 gcgccaccgc ccagccggtg gacgaggtgt acgagcggac ggcacggtca ggcgtgggcc
      541 tcggcccggt cttccagggg ctgcgggccg tctggcgtcg cggcgacgag acgtatgccg
      601 aggtcgcgct gcccgagccg atgagcgaat cggccgcggc ctacaacatg catccggcgc
      661 tgctggacgc ggtggcgcgg gtcgccgccg agggcggggc tgccgaggcc gagctggcct
      721 ccgcctggtc gggagtcgaa tccttcgccg tgggtgggtc gtccgtacgc gtgagtgtcg
      781 tgccgtcggc cgacggcgag gtgtcgatag ccgttgccga cgacaccggt gcgccggtcc
      841 tgtcggtcgc gaggctggcc acccgccagg tcatgcagaa ggaactgcgt tccgcggaca
      901 gggcgttgcg ggacgcgctc ttcgacgtgg agtggacccg ggttcagggt tcctgcgcgc
      961 cgccgacggg ctggagcgag tggggctctc cggaagaggg cccggccgtt cccgagctgc
     1021 tcgtcctgcc ccacagcggg gaggcggatc ccacggcggc aacggcacgc gccctgaccg
     1081 tcctgcgtga cttcctgtcg gacgagcggt tcgtcgatac gcgtctggtg gtgctgacgc
     1141 gcggtgctgt gggcacgcgc cccaaggagg gcatagcgga tctggcggcg gccccggtct
     1201 ggggcctggt gcgctccgcg caggcggagc accccgaccg gctggtgctg gtggacgtcg
     1261 agccgggcct ggacgcggtc gccgaggcag ccgccctgcg catcgcgctc ggcacggcag
     1321 agccgcaggt cgccgtacgc ggcggcaagg ccctgctgcc gcgtttggtg cgcaccaagg
     1381 ggccgtcgga actgcgcgat gagcggccgg gtttcggccc gcagggaacg gtccttgtga
     1441 ccggcggcac gggtggtctc ggcgcgctgg tggcccggca cctggtatcg gcgtacggcg
     1501 tacgcgagct gttgctggtc tcccggcgcg gctcggccgc cgagggtgtg gacgaactca
     1561 tcgccggtct tgaagagtcg ggtgcccgcg tccgcgtcga ggcgtgcgac gtgagcgatc
     1621 gcgccgcact cgccgcgctg ctcgcggccc tccccgagga ccggcccctc accggcgtcg
     1681 tccactgcgc gggtgtcatc gacgacggcg tgatcgagtc gctcgacgag gagcgcctgg
     1741 cccgggtgtt ccggccgaag gtggacgcgg cgctgcacct gcacgagctg acggcggacc
     1801 tcggcctcag cgcgttcgtg ctgttctcct ccgtggccgg tgtgttcggc gcggcgggcc
     1861 gggccaacta cgccgccgcg aacaccttcc tggacgctct cgcgtacgag cgccgcgcgc
     1921 agggtctcac tgccgtgtcc gccgcttggg gactgtggga ggaggaccgc ggcatgggcg
     1981 gccacgtgac cggggccgac ctggcccgga tccggcggga gggtgctgtc gcgatgtccg
     2041 cggaggaggg gctcgcgctg ttcgacgcgg tcctcgccca cgaccgggag ctgtgcgtcc
     2101 cggcccgcct ggacctggcc tccatcgccg gggccggctc cccgccgccg cccgtgcttc
     2161 ggcagctcgt accacccgcg cgcaggcacc tcgacgcgca gggcgccttc cggcaggacg
     2221 acgctccggt gaacaccgcc gagaagcttg ccggaaacct ggccgggctg acggaagccg
     2281 agcagatgcg taccctgctc ggcctcgtgc gcggccatgt cgccactgtc ctcgggcacg
     2341 ccgacctcga ggcggtctcc cccgaccggg gcttcctgga ctccggtttc agctcggtgg
     2401 ccgtggtcga actacgcaac cgcctcagca ggtccaccgg cctgcgcttc tccgcggtca
     2461 cgctgttcga ccaccccacg ccccgggccg tcgcgcggca tctccgggaa aggctggccc
     2521 ccgactccgt caccggaaac ggcccggcgg tcaccggcgc ggaactcggc aggaccgacg
     2581 ccgcggactt ccgtgccgcc ctgtcggccg ttccgctcgc ccgcctcaag gaggtcggcg
     2641 tcctggacgc cctgctgcgg ctcaccggat tcgacggtga acccgacggg cgggccggcg
     2701 ccgccgaccc cacggccgtg acacccatga cgccggagtc catcgacgcc atggacctgg
     2761 acagcctcgt cgacatggcg atcaacaccg acctctgaac aaccttcggg agtttgctga
     2821 tggacaccac cgacgatcgc gtcgtacagg cgctgcgcgc gtcgatcaag gaaaccgagc
     2881 ggctgaagca gcagcaccag cagctcgtgg agtcactgaa cgagccgatc gccatcatcg
     2941 gcatggcctg ccgcttcccc ggcggggttg tctcgccgga ggacctgtgg cagctcgtgg
     3001 tcgacggcgg cgacgcgatc ggcccctttc ccgacgaccg tggctgggac ctcgaagcgc
     3061 tctacgaccc cgagcagcgc cgcaaaggca ccctctacgt gcgagagggc ggcttcgtcg
     3121 agggcgccgc cgacttcgac gcggcgttct tcggtgtgag cccgcgcgag gccaccgcca
     3181 tggacccgca gcagcggctg ctcctggaga cgggttggga gtccttcgag cgggccggca
     3241 tcgacccgac cggcctgcgc ggctcggacg tcggtgtgtt ctccggcacc aacatccagg
     3301 actaccagtc gctgctgctg acctctccgg gcgccttcga aggacacgtg ggcacgggca
     3361 acgccgccgc tgtgctctcc ggccgcctcg cctacacctt cggcttcgaa gggcccgcgg
     3421 tcaccgtcga cacggcgtgc tcgtcctcgc tggtcgccct gcacctggcc gcgcaggctc
     3481 tgcggcagcg ggagtgctcc ctggccttgg cgggcggcgt gacgctgatg tccaccccga
     3541 tgggcttcgt cgagtacagc gggcagcgag tgctcgccag ggacgggcgc tgcaagtcgt
     3601 tcgccgggtc cgccgacggc accgggttct ccgagggcgt cggcatgttc ctgctggagc
     3661 ggctctcgga cgcccggcgc aacggccgtc gcatccaggg cctgatccgt ggctccgccg
     3721 tcaaccagga cggagcgagc agcaacctga ccgctcccaa cggtcgtgcc cagcaacgcg
     3781 tcatccttca ggccctggcg aacgctcaag tctcctcgga ccaggtcgac gtcctggagg
     3841 cacacggcac cggtaccgaa ctcggcgacc ccatagaggc ggaggccctg ctcgccacct
     3901 acggcaagga ccgcacgccg gaacgcccgc tgtggctcgg ctccgtgaag tcgaacatcg
     3961 ggcacactca ggccgccgcc ggacttgccg gagtgatcaa aatggtcctg gccatgcagc
     4021 acggcctggt gcccaggaca gtgcatgtcg acgagccgtc gccgcacgtc gactgggagt
     4081 ccggcacggt ccgcctggcg accgagcccg tggcctggcc ggagaacggg cggccgcgtc
     4141 gcgccggggt gtcgtccttc ggcatcagcg gcaccaacgc gcacgtcatc gtcgaacagg
     4201 ccccgccgga cccggctgcc atcgagccgg cggcgcggac cgccgagccc gacggcccat
     4261 tcgcgtggac ggtctccggg cgcagcgacc aggcgttgcg cgcccaggcg gaacggctcg
     4321 ccgcccacct gcgcgatcgg ccgcagctgt ccgcggcgga cgtggccgtg tcgaccgcgg
     4381 gccgcaccgc cttcgagcac cgcgcggtcg tggtcggcgg cgacctcgcc gacctggagg
     4441 ccggactcgc ggcgctggcc gccgggcgtg aggacgcgcg cctggtcaag ggcgtgacca
     4501 tcccgtcggg gcagacagtg ttcgtcttcc ccggacaggg ctcgcattgg ccggagatgg
     4561 ccgggcggct cctggagtct tcggcggtgt tccgcgaaag catcgacgag tgcgccgagg
     4621 cgctctccgc gtacgtggac tggtcgttga cggacgtcct gcgtcaggag ccgggggcgc
     4681 cctcgctgga ccgcctggac gtggtgcagc cggtgctgtt ctccatgatg gtggcgctcg
     4741 ccgaggtgtg gcgcgcgcac ggtgtcgaac ccgacgccgt catcggacac tcacagggcg
     4801 agatcgccgc cgcgtgcgtc gcgggcgcgc tgtccctgca ggacgcggcc cgcatcgtca
     4861 ccctgcgcag cgtcctgctg aaccggctga ccggcaaggg cgccatggcg tcgttcctgc
     4921 tctccgccga cgaggtggcg cggcgcatcg agccgtacgg cgaccggctg tcgatcgccg
     4981 ctgtgaacgg ccccacctcc gtcgtggtgt ccggcgagcc ggaggcagtc ggcgaactgg
     5041 tggcgacgtg cctggccgag cgggtgcggg cccggaaggt gcccggcgcg acagccgccg
     5101 gtcactccgc gcaggtcgac gcgctgcgcg gagagttcat cgagggcatc gcctccgtct
     5161 gcccgcgtcg tgcgattgtg cccttctact cgacggttgc cggggaagtg gtcgacacgg
     5221 ccaccctcga tgccacgtac tggtaccgca acctgcgcga gccggtcctc ctggaaggga
     5281 ccgtacgccg cctcctggcg gacgagcacc ggtacttcat cgagatcagc ccgcaccccg
     5341 tgctgaccgt ggggctccag gagactttcg agcaggcggg cacggcggcc acggccgtcg
     5401 gcaccctgcg ccgcgacgag ggcgtggagg cccgcttcct cacctcggcc gccgaggcgt
     5461 acgtacgggg actgccgctg gacctgggcc gcctgccgca gctgtcgggt gcccgccgtg
     5521 ccgacctgcc gacctacgcc ttccagcgca ggaggttctg gccggacgag cggatcgcgg
     5581 cagccgccgc agtgcccctg cgggacggcg cgatggccac cgcggacgcc acgcgcgccg
     5641 gacacgacga cccgtccgcg gtgaacgacc ccggacaggt gctgcgccgc ctggccgaac
     5701 tgccccacga ggagcacgac gcgttcctcg tggatctggt gtgcgagcag gccgccgcgg
     5761 tcctcggcca cggctcggca gcggagatgg agccggcgcg gcccttccag gagctgggat
     5821 tcgactcgct gaccgcggtc gaactgcgca accgcctcgg cgccgcactc gacctcgctc
     5881 tgcccgtcac cctggtcttc gaccatccca cgccgcggga cctggccgac cacctcgcgt
     5941 cacaggtcga gggaacgctg ccgggcccgg gctccgccac tcgttccgag gcgatcggcc
     6001 acctcgagaa gttggaggcc gtgctcgccg aactgggtgc cgaccccggc gagaacaagg
     6061 agatcggcct gcggctgcag cgcatcctca ccgagtggac gcaggcccgt gaggcagcga
     6121 atgacgcggt cggggaagcc gaggtgagca gcgaactgca aggggcctcg gacgaggaga
     6181 tgttcgacct catcggcaag aagttcggga tctcgtagat cggtcatcgc accgcagtcc
     6241 gacgaatcag gtgtgaaggg tgtgaagggg ccggcatggc tgacgaagac aagctccgct
     6301 actacttgaa gcggatggcc gccgaacttg aggcgacgca ggaacagttg cgcgaggcga
     6361 cggccatgcg cagcgaaccc gtcgcgatcg tgggcatggc ctgccgctac cccggaggcg
     6421 ccgacacccc ggagcggctc tgggaactcc tggcggcggg cgaggacgcg gtcgggaagt
     6481 ttcccgacga ccgcggatgg aacgccggtc ccaccgacgg tccgtatgcc gcggaggggg
     6541 ggttcctgta cgacgcggcg gagttcgatg cgggtttctt cgggatctcg ccgcgtgagg
     6601 cgctggcgat ggacccgcag cagcggctgt tgctggaggt gtcctgggag gcgatcgagc
     6661 ggtcgggcat cgacccgaag tctctgaagg gcacccagac cggggcgttc ctgagcacca
     6721 gctatcagga gtacctggcc cggctgcagc agaccggggc ggccgtcgac gcgttcaagc
     6781 tgtccgggaa ctgcgtgagc gtggcatccg gccgggtctc gtacgtcctc gggctgtcgg
     6841 gccccgcggt gacgctggac acggcgtgtt cgtcggctct ggtcgcagta catctggcgg
     6901 cggactcgct gaggcgcggc gagagcacct tggctctcgc gggcgccgcc acggtcatgg
     6961 ccaccgaggg catgttcgtg gagttcgatc ggcagggtgg tctgtcggcg gatgggcggt
     7021 gcaaggcgtt cggtgcgggg gcggacggta cgggctggtc cgagggtgtg ggtgtgctgg
     7081 tcc
//
