LOCUS       NZ_BMWB01000046        20693 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces xantholiticus strain JCM 4863 sequence46, whole genome
            shotgun sequence.
ACCESSION   NZ_BMWB01000046
VERSION     NZ_BMWB01000046.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces xantholiticus
  ORGANISM  Streptomyces xantholiticus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 20693)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 114X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014651015.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:24:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,091
            CDSs (total)                      :: 7,016
            Genes (coding)                    :: 6,693
            CDSs (with protein)               :: 6,693
            Genes (RNA)                       :: 75
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 323
            CDSs (without protein)            :: 323
            Pseudo Genes (ambiguous residues) :: 0 of 323
            Pseudo Genes (frameshifted)       :: 187 of 323
            Pseudo Genes (incomplete)         :: 270 of 323
            Pseudo Genes (internal stop)      :: 13 of 323
            Pseudo Genes (multiple problems)  :: 140 of 323
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:39:19
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 20693
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMWB01000046.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     gene            complement(<1..1135)
                     /locus_tag="IE198_RS34085"
                     /pseudo=""
     CDS             complement(<1..1135)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018522253.1"
                     /locus_tag="IE198_RS34085"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="Fe-S oxidoreductase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MQLTAIIVSLVLTVLGVALIGRAVAQIYRFVRLGQPVPAGSRTDN
                     WQARSVTLAKEFIGHTRMNRWGIVGIAHWFVAVGFLTLGLTILTAYCQLFKADFVLPIL
                     GGWLPYELYTEFIALGTTVGIIVLIAIRQLNLPSRAGRKSRFAGSTAWQAYFVEYVIVV
                     IGLAIMTLRGLEGAIHHVDHYEAAYFASYPLVVAFHDLDVSTLQNLTYLAAMVKLGTTM
                     IWAITISLNTDMGVAWHRFLGFPNIWFKRNATGESALGELKPMTSGGKEIDFEDPGEDD
                     TFGVSQVEQFSWKGILDFSTCTECGRCQSQCPAWNTGKPLSPKLLIMSLRDHAHAKAPY
                     LLAGGGKTMEGEEKASKEQLKDVPAAALAEAERPLIGT"
     source          1..20693
                     /culture_collection="JCM:4863"
                     /db_xref="taxon:68285"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces xantholiticus"
                     /strain="JCM 4863"
                     /submitter_seqid="sequence46"
                     /type_material="type strain of Streptomyces xantholiticus"
     region          1..20693
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..20693
                     /SMILES="C(C)C(=O)C(CC)=CC(C)=CC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20693
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[5343:19299](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5344..19299
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     gene            complement(1381..1989)
                     /locus_tag="IE198_RS34090"
                     /old_locus_tag="GCM10010381_69400"
     CDS             complement(1381..1989)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571808.1"
                     /locus_tag="IE198_RS34090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_69400"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_189893837.1"
                     /transl_table=11
                     /translation="MSPELRRQMIVRSTLSLITEHGPAVTTGRIARAAAISEATIFHVF
                     SDKDELLDACMAEAARSDDVVYELADIPLDAPVTARLVAAAGVLEAYLTRVGTVITYLE
                     AGGHGRARRYSAASAGGMREVREAFDSVVASLAALLGPEEESLRLPAPHIAQAFFDLLF
                     ARSRNPDYRPHHPQLMEIVQLLVHGSLAGSSQTETAGAR"
     misc_feature    2035..2052
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.25"
                     /tool="antismash"
     gene            complement(2273..3310)
                     /locus_tag="IE198_RS34095"
                     /old_locus_tag="GCM10010381_69410"
     CDS             complement(2273..3310)
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012517.5"
                     /locus_tag="IE198_RS34095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_69410"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_189893839.1"
                     /transl_table=11
                     /translation="MSRRGGHITLFTQLFTAPETTCGDSQAADAGAFARVLDRARAAED
                     AGIDALLLHDRQSASHDPAGDPSFEAGTLAAALAVRTRTVGLVAAVSTEYALPYHVART
                     LATIDHITLGRAGWQPITTADPDASANYSRSGTESAAARRARASEFVTVLTGLWDSFDD
                     DAFRRDRESGVYFTPEKLHTLDHKGECFDVAGPLNIARPPQGHPPLVHRAADGDDFALA
                     ARAADVVLLPARNGQDPVLLRESVRDQVRAAGRDPDDVAVLLDWPVDGSADAAGRLREL
                     FDAGVADGFTLLAPDGAAGTAHEAVIALAAAVRADGPAEQAAQGGATLRDRLSLPRPTG
                     RYQTV"
     gene            complement(3307..4629)
                     /locus_tag="IE198_RS34100"
                     /old_locus_tag="GCM10010381_69420"
     CDS             complement(3307..4629)
                     /EC_number="1.14.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (MITE)
                     MITE0000147: Hydroxylation (98% identity)"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321872.1"
                     /locus_tag="IE198_RS34100"
                     /note="This protein belongs to a clade of FMN-dependent
                     monooxygenases, within a broader family of flavin-dependent
                     oxidoreductases, the luciferase-like monooxygenase (LMM)
                     family, some of whose members use coenzyme F420 rather than
                     FMN; Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_69420"
                     /product="NtaA/DmoA family FMN-dependent monooxygenase"
                     /protein_id="WP_189893841.1"
                     /transl_table=11
                     /translation="MVHQKRTMRLGAIIDGPGSHIAAWRHPSTPVDAQLDFAFHLACAR
                     TLERGMFDCLFVPDVVALWGTDVEHISKTARNEHFEPLSLLAAYAAGTDHIGLASTATT
                     TYNEPYDIARRFTSLDRISGGRAGWNVVTSAAPWESRNFGHPEHMEHDRRYVRAEEFIG
                     VTKRLWATGPQAGAARESRHAHCGEFFDVQGPLNLPASPQGSPVIFQAGASPVGREFAA
                     RHAEVIFTRHTQLSDGQETYADLKRRVTAHGRDPERVQIWPGVQPLVAGTEEEARRLIN
                     ELHDLVPDIVAIRALQEQLGDLDLTRYPLDGPVPDIPTSNRSSSTRRMWTSLAHRENLT
                     LRQLALRQVADFFAGTPEQVADHLERGFTERAADGYVVDFPHLPSSLDAFVDHVVPELR
                     RRGLVQDEYTDGTLREKLGLVAPCSDGATRTGEPALQAGAA"
     misc_feature    5312..5326
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.88"
                     /tool="antismash"
     misc_feature    5322..5331
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.85"
                     /tool="antismash"
     gene            5344..19299
                     /locus_tag="IE198_RS34105"
                     /old_locus_tag="GCM10010381_69430"
     CDS             5344..19299
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (17-431). E-value:
                     2.3e-158. Score: 519.5. Matches aSDomain:
                     nrpspksdomains_IE198_RS34105_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (565-865). E-value: 1.1e-104.
                     Score: 342.0. Matches aSDomain:
                     nrpspksdomains_IE198_RS34105_PKS_AT.1"
                     /NRPS_PKS="Domain: ACP (955-1027). E-value: 3.1e-27. Score:
                     86.7. Matches aSDomain: nrpspksdomains_IE198_RS34105_ACP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (1050-1476). E-value:
                     6.9e-187. Score: 613.5. Matches aSDomain:
                     nrpspksdomains_IE198_RS34105_PKS_KS.2"
                     /NRPS_PKS="Domain: PKS_AT (1592-1890). E-value: 5.2e-98.
                     Score: 320.0. Matches aSDomain:
                     nrpspksdomains_IE198_RS34105_PKS_AT.2"
                     /NRPS_PKS="Domain: PKS_DH (1959-2128). E-value: 3.5e-63.
                     Score: 204.8. Matches aSDomain:
                     nrpspksdomains_IE198_RS34105_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (2443-2624). E-value: 4.3e-62.
                     Score: 201.2. Matches aSDomain:
                     nrpspksdomains_IE198_RS34105_PKS_KR.1"
                     /NRPS_PKS="Domain: ACP (2730-2802). E-value: 3.1e-30.
                     Score: 96.3. Matches aSDomain:
                     nrpspksdomains_IE198_RS34105_ACP.2"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (2827-3251). E-value:
                     3.7e-182. Score: 597.9. Matches aSDomain:
                     nrpspksdomains_IE198_RS34105_PKS_KS.3"
                     /NRPS_PKS="Domain: PKS_AT (3367-3665). E-value: 7.3e-104.
                     Score: 339.2. Matches aSDomain:
                     nrpspksdomains_IE198_RS34105_PKS_AT.3"
                     /NRPS_PKS="Domain: PKS_DH (3732-3903). E-value: 9.6e-63.
                     Score: 203.4. Matches aSDomain:
                     nrpspksdomains_IE198_RS34105_PKS_DH.2"
                     /NRPS_PKS="Domain: PKS_KR (4192-4371). E-value: 7.2e-58.
                     Score: 187.5. Matches aSDomain:
                     nrpspksdomains_IE198_RS34105_PKS_KR.2"
                     /NRPS_PKS="Domain: PKS_PP (4466-4551). E-value: 1.9e-31.
                     Score: 100.2. Matches aSDomain:
                     nrpspksdomains_IE198_RS34105_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (4564-4650). E-value:
                     1.3e-12. Score: 40.4. Matches aSDomain:
                     nrpspksdomains_IE198_RS34105_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003970494.1"
                     /locus_tag="IE198_RS34105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_69430"
                     /product="type I polyketide synthase"
                     /protein_id="WP_189893843.1"
                     /sec_met_domain="PKS_KS (E-value: 2.3e-159, bitscore:
                     519.5, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.1e-105, bitscore:
                     342.0, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 8.4e-96, bitscore:
                     309.0, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1e-65, bitscore:
                     209.7, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 5.9e-234, bitscore:
                     765.2, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.6e-17, bitscore:
                     52.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGEAVSERGGRNAGAEIAVVGFSCRVAGAATPDEFWQLLKDGRS
                     EVKEFPVARRADQGPDFPDLPGGYLESVDGFDADLFEVSPAEAAAMDPQQRLALELSWE
                     AVEHSGASPDALRGTRTGVFVGAINDDYAALLHHRGTGSVTRHSLTGTQRSFIANRISY
                     RLGLRGPSVLVDSGQSSSLVAVHLGVQSLLRGESDAVLAGGVNLILSEHSTSSLKHFGA
                     LSPDGRCYTFDARANGYARGEGGGFVLLKSLERAVADGDRVLAVIEGSAVNNDGGGDGL
                     TVPSAAAQHELLRDACDAAGMSPADIQCVELHGTGTKVGDPLEASAIGQALGAERSDDR
                     PVRVGSVKTNIGHLEAAAGIVGLLKVVSCVSRRELVPTLNQETGNPRIPFTEWNLEVQR
                     AHEQWRGENGRLIAGVSSFGLGGTNCHVVIGDPPPELRGGHQGQSGQAGHGGESPSEPV
                     PTSPTTRGPVPWPISARGEAALRGQAEQLDTHVRQRPEADVHAVGRGLAAGRARFEHRA
                     VVVGEDGPSLRAGLRAVSAGAGAANVVRGVAGDSRADGDAEAQSGVVFVFPGQGAQWAG
                     MAVGLLESSPVFAERMAACEAALSPYVEWSLAEVVRDLADASRLDRVDVVQPVLWAVMV
                     SLAEVWRSTGVEPAAVVGHSQGEIAAAVVAGVLSLSDGARVVALRSRAIRQDLSERGGM
                     VAVSTGAAAAAELIAEFGGQLSVGAVNGPSSTVVSGAPRALEELFARCESEGIRARRVP
                     VDYASHCAEVEVVRDEVLRELTGITPARAEVPYYSTVTGGPVTGSELDAEYWYRNLRQT
                     VRFEESVRAAVADGFTRFVEVSAHPVLVTGVEETLEAAGVGEHGLVLGTLRRDEGGWDR
                     FLLSAAEAWTRGVDVDWSALLGPGPRATGLPTYAFQRRRHWLDTAARSRTVTEPEGTTA
                     QGARAGGPEQEVQAPAGDVTPERVADLVRDEVAVVLGHSSSHDIDMGRTFKALGFDSVA
                     MVDLRNRLRAATGVNLTTTALFDHPTPSATATHLRSRLLGLDEAAAEGPAERAAGGADD
                     EPIAIVAMACRFPGGVETPEDLWDLLIAERDVIGDFPVNRGWDLENLYDPQSERHGTSY
                     VRHGGFLHDAGEFDADFFGISPREALAMDPQQRLLLETSWEALERAGLDPSSLRGSRTG
                     VFLGAMFQEYGPQLQHGSEEVAGHRLTGGTISVASGRVAYTLGLEGPAVTVDTACSSSL
                     VALHWAVRSLRSGECSMALAGGVTIMPTPGMFVELSRQGALSPDGRCKAFSSTADGTGW
                     AEGVGVLLVERLSDARRNGHQVLAVVRGSATNQDGASNGLTAPHGPAQQRVIRAALADA
                     GLTPDDVDVVEAHGTGTQLGDPIEAQALLSTYGQRRPGSRPLRLGSVKSNIGHTQAAAG
                     VAGVIKTVMAMRRGMLPRTLHVAEPSPHIDWTAGAVELLTEPQKWTADGRPRRAGVSSF
                     GISGTNGHVILEEAPGDAQVRSARPAAADASGGTGLGAAGGPVPWVVSGRSEEGLRAQA
                     GRLSAFARARTDMSALDMGWSLAASRAVHEHRAVVLRADRDAGLAGLSALAGGQPAAGV
                     VTGAADVRGRVVFVFPGQGSQWQGMAAELLDSSAVFAARLTEVDAALGKFVDWSVTDVL
                     RQEPHAPSAERIEILQPVLFAVNVSLAAVWQASGVQPAAVVGHSQGEIAAAHVAGALSL
                     EDAAKLIVLRSGLFARELVGKGAVASVALPADAVEERLTPWQDRLVVAGRNGPRATTVA
                     GDVPALEEFVASCKKDGVRARIVGSTVASHCAQVDPLREEILELFADITPVKGSVPFYS
                     TVTGSVRDGEELTAGYWFDNARRPVNFEGTVRTLLADGFRFFVESSAHPVLTTGVQATA
                     EEAEIEAVAIGSLRRDEGGPARFLTSLAEGYVRGLPGVEWKALFAGADARLIELPVYAF
                     QRRRYWLGTTAEGTGDPRRLGLGAAHHPLIGAVVRSAAGGDALLTGRLSLQTHPWLADH
                     TAMGGALLPGAAFVELALRAGDAVGCDRLNELTLEAPLVLPERGGVQVQVAAKAPDADG
                     RSHVAVYARPEAEADADPDEPWTRHATGLLDMADTAPDGSADPTAWPPPGAERIDLDSF
                     YERAADAGYGYGPAFQGLRAAWGVGGEVYAEVALGDEQRTDAGRFGIHPALLDAALHPA
                     LLSALDDQPPVLRLPFAWRGVALHAVGAASARVRVAPAGADAVSVTITDATGAPVASVD
                     SLTLRAVSPRQLTGASDAGRNALFRTVWTPLPDPGAARDTSGLVVLGTPRTGLFDTAGH
                     APDLAALYADGAAPDVVVATCGPAGRDLAAAAHTATTDMQRLAQAWLSEERAARSVLVV
                     VTRGAVSARPGEDVVDLAHAPVWGLLRSAQSENPGRFLLVDVDDLDASREALATAVMTA
                     VAAQEPQLAVREGTALVPRLTRAPAPGQDDSRASFGPHGTVLITGGTGALGGLLARHLV
                     TEHGVRHLLLTSRRGKEAHGTAELVAELTESGAEHVEVAVCDAADREALAAVLAAVPAE
                     RPLTGVVHAAGVLDDGMLTSLTAERTQRVLRPKIDGALNLHELTRGLELSAFVLFSSIA
                     GTFGNPGQANYAAANAFLDALAQHRRAQGLPAHALAWGLWAESGDMLGHLADHDLAWMK
                     RAGVRPLPSAEGLALLDTAVTRDEAHLIPVRLEMATLRTEAASGMLRPLFRGLVRPQGR
                     RATPTAESTGGTSLAQRLSGLATNEQSRVLLDLVRAQVATVLGHADSSTIAASRPFQEI
                     GFDSLTAVELRNRLSAAVGQRLPATLVFDHPTPALITEYLRVELLGAPPATTAVPPRPV
                     VPGGAAEEPIAIVGMACRYPGGVGSPDDLWRLVEDGGDAVSFFPTDRGWDDGLYDPDPD
                     SAGKTYAREGGFLYDAGEFDADFFGISPREALAMDPQQRLLLETSWEVFERSGMDPTTL
                     RGSSTGVFTGVMHHDYGADSETPAGLEGYAVTSTQGSVASGRIAYTFGLEGPAVTVDTA
                     CSSSLVALHLAVQALRSGECSLALAGGVTVMATPWVFVEFSRQRGMAPDGRCKAFSAAA
                     DGAGWSEGVGVLLVERLSDARRNGHQVLAVVRGSAVNQDGASNGLTAPNGPAQQRVIRA
                     ALAGAGLSSADVDVVEAHGTGTTLGDPIEAQAVLATYGQDRPADRPLRLGSIKSNIGHA
                     QAAAGVAGVIKMVQAVRHGVLPRTLHADEPSPHVDWSAGAVELLTERADWATDGRPRRA
                     GVSSFGISGTNAHVIIEEAPEEPRSEQEQEPAGTTTDATGDTSAALLPWPVSGRTEAAL
                     RAQAERLAAWAGAETGLRLPDVGHSLATTRAHLEHRGVVLASNRTKTLAGLTALADGLP
                     AEGVVTGTAPEEPGRVAFVFPGQGSQWQGMAAELLETSPVFAARLAECDAALRPYTGWS
                     VTDAVRGGQGAPPLDDVVVVQSALWAVMVSLAAQWQSLGVRPDAVIGHSQGEIAAAAVS
                     GALSLDDAAKVVSLRAQAIARNLSGRGGMVSVPLRADDVRERLARWGERISVASVNGPR
                     STVVSGEPEALDELLAACEADEVPARRIPVDYASHSAQVEAIREEVLAALADIEPRCGE
                     IPFYSTVTGGLFDTSGADAEYWYTNLRQEVRFDETVRALLTDGFGFFVESSARPVLTIG
                     LEETFEDTGSRAVALGTLRRDEGGWERFLTSLAEGYVHGLPVDWDAVFAGADAHRADLP
                     TYAFQRERFWLDVPARRGDVAGLGLAEAGHPLLGAVVSLPDDRGALWTGRLSLAEQPWL
                     ADHAVFGSVVLPGAVLVELALQAGGRVACGRLEELTLQQPLVLGDAGGVRLQVAVTGAD
                     EAGRRAVTVHSCPDGGGADEAVPGGETWTLHATGTLVDGGGPFAAADLAAWPPRGAEKV
                     DVSDLYDRLADQGYGYGPAFQGVRTAWRRGAETYAEVALPGVVSGQAAGYGVHPALLDA
                     VFHMSIDLGAEEVRLPFMWSGVEVSGASTSPVVRVAFHPAADGELSLRVVDEAGTPVLS
                     VDRLVTRPVAREQLRGAGGALREALFGMEWAPGPSGSRTSTEWSEWDALDEAEAAPGTV
                     LWPHGGAAGESVSAATARALGIVQEFLSAERFAGSRLVILTRGAVGTSADERVTALTAA
                     PVWGLVRSAQVEHPDRLVLVDVEPGLSPAAEEAALRTALRGAEPQVAVRGGKALVPRLS
                     RIEAGRQDTARPRFDPKGTVLVTGGTGGLGALVARHLVSAYGVRDLLLVSRRGKAADGV
                     DALVAELNRSGARVRVEACDVSDRAALATLLASVPQDRPLTGVVHSAAVLDDGVIEALD
                     AERLAGVFRPKTDAALHLHELTAGLGLSAFVLFSSFAGVVGSAGQAGYAAANVFLDALA
                     HERRAQGLPAVSLAWGWWGSDGGLTGGLSDVDRGRLSALGLAEMSGEEGLALLDAGLAA
                     DRAVVVPALLDVAGLRRRGVEDVPVVLRSLVRGGPRHAQDRIAEAGTVEGLAARVAGLS
                     EAERERVVLDLVRGHVSGVLGYGPGRLVDLETPFKALGFDSLMAVELRNRLNRATGLRL
                     PASLVFDHPTVQELTRYVVTRLEQESGPGTGAGAEPILADLGKVEQALTGTDLGGDARQ
                     RIAERLMDLLTLSGPEGDPVGPLTQADPGTDGEDGGGTAFVDQLEAATPDEILDVIEKE
                     FGNL"
     aSDomain        5395..6636
                     /ASF="found active site cysteine: False, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34105_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="2.30E-158"
                     /label="IE198_RS34105_PKS_KS.1"
                     /locus_tag="IE198_RS34105"
                     /protein_end="431"
                     /protein_start="17"
                     /score="519.5"
                     /tool="antismash"
                     /translation="IAVVGFSCRVAGAATPDEFWQLLKDGRSEVKEFPVARRADQGPDF
                     PDLPGGYLESVDGFDADLFEVSPAEAAAMDPQQRLALELSWEAVEHSGASPDALRGTRT
                     GVFVGAINDDYAALLHHRGTGSVTRHSLTGTQRSFIANRISYRLGLRGPSVLVDSGQSS
                     SLVAVHLGVQSLLRGESDAVLAGGVNLILSEHSTSSLKHFGALSPDGRCYTFDARANGY
                     ARGEGGGFVLLKSLERAVADGDRVLAVIEGSAVNNDGGGDGLTVPSAAAQHELLRDACD
                     AAGMSPADIQCVELHGTGTKVGDPLEASAIGQALGAERSDDRPVRVGSVKTNIGHLEAA
                     AGIVGLLKVVSCVSRRELVPTLNQETGNPRIPFTEWNLEVQRAHEQWRGENGRLIAGVS
                     SFGLGGTNCHVVIGD"
     aSModule        5395..8424
                     /complete
                     /domains="nrpspksdomains_IE198_RS34105_PKS_KS.1"
                     /domains="nrpspksdomains_IE198_RS34105_PKS_AT.1"
                     /domains="nrpspksdomains_IE198_RS34105_ACP.1"
                     /locus_tags="IE198_RS34105"
                     /monomer_pairings="mmal -> Me-mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       5617..5643
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0001"
                     /evalue="1.20E-01"
                     /label="PKSI-KS_m2"
                     /locus_tag="IE198_RS34105"
                     /protein_end="100"
                     /protein_start="91"
                     /score="5.8"
                     /tool="antismash"
                     /translation="DPQQRLALE"
     CDS_motif       5848..5895
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0002"
                     /evalue="3.20E-02"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE198_RS34105"
                     /protein_end="184"
                     /protein_start="168"
                     /score="7.3"
                     /tool="antismash"
                     /translation="GPSVLVDSGQSSSLVA"
     CDS_motif       6037..6075
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0003"
                     /evalue="5.80E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="IE198_RS34105"
                     /protein_end="244"
                     /protein_start="231"
                     /score="13.0"
                     /tool="antismash"
                     /translation="FDARANGYARGEG"
     CDS_motif       6271..6315
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0004"
                     /evalue="4.60E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE198_RS34105"
                     /protein_end="324"
                     /protein_start="309"
                     /score="9.8"
                     /tool="antismash"
                     /translation="VELHGTGTKVGDPLE"
     CDS_motif       6376..6420
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0005"
                     /evalue="1.00E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE198_RS34105"
                     /protein_end="359"
                     /protein_start="344"
                     /score="11.6"
                     /tool="antismash"
                     /translation="GSVKTNIGHLEAAAG"
     CDS_motif       7033..7089
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0006"
                     /evalue="1.40E-08"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE198_RS34105"
                     /protein_end="582"
                     /protein_start="563"
                     /score="26.5"
                     /tool="antismash"
                     /translation="VFVFPGQGAQWAGMAVGLL"
     aSDomain        7039..7938
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34105_PKS_AT.1"
                     /evalue="1.10E-104"
                     /label="IE198_RS34105_PKS_AT.1"
                     /locus_tag="IE198_RS34105"
                     /protein_end="865"
                     /protein_start="565"
                     /score="342.0"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGAQWAGMAVGLLESSPVFAERMAACEAALSPYVEWSLAEV
                     VRDLADASRLDRVDVVQPVLWAVMVSLAEVWRSTGVEPAAVVGHSQGEIAAAVVAGVLS
                     LSDGARVVALRSRAIRQDLSERGGMVAVSTGAAAAAELIAEFGGQLSVGAVNGPSSTVV
                     SGAPRALEELFARCESEGIRARRVPVDYASHCAEVEVVRDEVLRELTGITPARAEVPYY
                     STVTGGPVTGSELDAEYWYRNLRQTVRFEESVRAAVADGFTRFVEVSAHPVLVTGVEET
                     LEAAGVGEHGLVLGTLRRD"
     CDS_motif       7201..7272
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0007"
                     /evalue="1.40E-09"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="IE198_RS34105"
                     /protein_end="643"
                     /protein_start="619"
                     /score="30.1"
                     /tool="antismash"
                     /translation="LDRVDVVQPVLWAVMVSLAEVWRS"
     CDS_motif       7276..7386
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0008"
                     /evalue="4.70E-18"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="IE198_RS34105"
                     /protein_end="681"
                     /protein_start="644"
                     /score="57.0"
                     /tool="antismash"
                     /translation="GVEPAAVVGHSQGEIAAAVVAGVLSLSDGARVVALRS"
     CDS_motif       7498..7533
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0009"
                     /evalue="5.00E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE198_RS34105"
                     /protein_end="730"
                     /protein_start="718"
                     /score="10.3"
                     /tool="antismash"
                     /translation="AVNGPSSTVVSG"
     CDS_motif       7603..7635
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0010"
                     /evalue="7.00E-02"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="IE198_RS34105"
                     /protein_end="764"
                     /protein_start="753"
                     /score="6.6"
                     /tool="antismash"
                     /translation="VDYASHCAEVE"
     CDS_motif       7693..7719
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0011"
                     /evalue="1.30E+01"
                     /label="PKSI-AT-mM_m7"
                     /locus_tag="IE198_RS34105"
                     /protein_end="792"
                     /protein_start="783"
                     /score="0.2"
                     /tool="antismash"
                     /translation="VPYYSTVTG"
     CDS_motif       7741..7788
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0012"
                     /evalue="1.80E-05"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="IE198_RS34105"
                     /protein_end="815"
                     /protein_start="799"
                     /score="16.7"
                     /tool="antismash"
                     /translation="LDAEYWYRNLRQTVRF"
     CDS_motif       7831..7860
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0013"
                     /evalue="2.80E-02"
                     /label="PKSI-AT-mM_m9"
                     /locus_tag="IE198_RS34105"
                     /protein_end="839"
                     /protein_start="829"
                     /score="7.6"
                     /tool="antismash"
                     /translation="FVEVSAHPVL"
     aSDomain        8209..8424
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34105_ACP.1"
                     /evalue="3.10E-27"
                     /label="IE198_RS34105_ACP.1"
                     /locus_tag="IE198_RS34105"
                     /protein_end="1027"
                     /protein_start="955"
                     /score="86.7"
                     /tool="antismash"
                     /translation="DLVRDEVAVVLGHSSSHDIDMGRTFKALGFDSVAMVDLRNRLRAA
                     TGVNLTTTALFDHPTPSATATHLRSRL"
     aSDomain        8494..9771
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34105_PKS_KS.2"
                     /domain_subtypes="Modular-KS"
                     /evalue="6.90E-187"
                     /label="IE198_RS34105_PKS_KS.2"
                     /locus_tag="IE198_RS34105"
                     /protein_end="1476"
                     /protein_start="1050"
                     /score="613.5"
                     /tool="antismash"
                     /translation="IAIVAMACRFPGGVETPEDLWDLLIAERDVIGDFPVNRGWDLENL
                     YDPQSERHGTSYVRHGGFLHDAGEFDADFFGISPREALAMDPQQRLLLETSWEALERAG
                     LDPSSLRGSRTGVFLGAMFQEYGPQLQHGSEEVAGHRLTGGTISVASGRVAYTLGLEGP
                     AVTVDTACSSSLVALHWAVRSLRSGECSMALAGGVTIMPTPGMFVELSRQGALSPDGRC
                     KAFSSTADGTGWAEGVGVLLVERLSDARRNGHQVLAVVRGSATNQDGASNGLTAPHGPA
                     QQRVIRAALADAGLTPDDVDVVEAHGTGTQLGDPIEAQALLSTYGQRRPGSRPLRLGSV
                     KSNIGHTQAAAGVAGVIKTVMAMRRGMLPRTLHVAEPSPHIDWTAGAVELLTEPQKWTA
                     DGRPRRAGVSSFGISGTNGHVILEEAP"
     aSModule        8494..13749
                     /complete
                     /domains="nrpspksdomains_IE198_RS34105_PKS_KS.2"
                     /domains="nrpspksdomains_IE198_RS34105_PKS_AT.2"
                     /domains="nrpspksdomains_IE198_RS34105_PKS_DH.1"
                     /domains="nrpspksdomains_IE198_RS34105_PKS_KR.1"
                     /domains="nrpspksdomains_IE198_RS34105_ACP.2"
                     /locus_tags="IE198_RS34105"
                     /monomer_pairings="emal -> ccemal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       8749..8775
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0014"
                     /evalue="9.20E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="IE198_RS34105"
                     /protein_end="1144"
                     /protein_start="1135"
                     /score="6.2"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     CDS_motif       8977..9024
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0015"
                     /evalue="2.60E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE198_RS34105"
                     /protein_end="1227"
                     /protein_start="1211"
                     /score="19.4"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     CDS_motif       9166..9204
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0016"
                     /evalue="2.20E+00"
                     /label="PKSI-KS_m4"
                     /locus_tag="IE198_RS34105"
                     /protein_end="1287"
                     /protein_start="1274"
                     /score="2.5"
                     /tool="antismash"
                     /translation="FSSTADGTGWAEG"
     CDS_motif       9400..9444
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0017"
                     /evalue="5.60E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE198_RS34105"
                     /protein_end="1367"
                     /protein_start="1352"
                     /score="12.2"
                     /tool="antismash"
                     /translation="VEAHGTGTQLGDPIE"
     CDS_motif       9505..9549
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0018"
                     /evalue="2.20E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE198_RS34105"
                     /protein_end="1402"
                     /protein_start="1387"
                     /score="10.7"
                     /tool="antismash"
                     /translation="GSVKSNIGHTQAAAG"
     CDS_motif       10114..10170
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0019"
                     /evalue="3.90E-09"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE198_RS34105"
                     /protein_end="1609"
                     /protein_start="1590"
                     /score="28.2"
                     /tool="antismash"
                     /translation="VFVFPGQGSQWQGMAAELL"
     aSDomain        10120..11013
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34105_PKS_AT.2"
                     /evalue="5.20E-98"
                     /label="IE198_RS34105_PKS_AT.2"
                     /locus_tag="IE198_RS34105"
                     /protein_end="1890"
                     /protein_start="1592"
                     /score="320.0"
                     /specificity="substrate consensus: emal"
                     /specificity="PKS signature: Ethylmalonyl-CoA"
                     /specificity="Minowa: emal"
                     /tool="antismash"
                     /translation="VFPGQGSQWQGMAAELLDSSAVFAARLTEVDAALGKFVDWSVTDV
                     LRQEPHAPSAERIEILQPVLFAVNVSLAAVWQASGVQPAAVVGHSQGEIAAAHVAGALS
                     LEDAAKLIVLRSGLFARELVGKGAVASVALPADAVEERLTPWQDRLVVAGRNGPRATTV
                     AGDVPALEEFVASCKKDGVRARIVGSTVASHCAQVDPLREEILELFADITPVKGSVPFY
                     STVTGSVRDGEELTAGYWFDNARRPVNFEGTVRTLLADGFRFFVESSAHPVLTTGVQAT
                     AEEAEIEAVAIGSLRRD"
     CDS_motif       10285..10353
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0020"
                     /evalue="1.70E-08"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="IE198_RS34105"
                     /protein_end="1670"
                     /protein_start="1647"
                     /score="26.8"
                     /tool="antismash"
                     /translation="ERIEILQPVLFAVNVSLAAVWQA"
     CDS_motif       10357..10467
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0021"
                     /evalue="4.00E-18"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="IE198_RS34105"
                     /protein_end="1708"
                     /protein_start="1671"
                     /score="57.3"
                     /tool="antismash"
                     /translation="GVQPAAVVGHSQGEIAAAHVAGALSLEDAAKLIVLRS"
     CDS_motif       10579..10617
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0022"
                     /evalue="7.80E-01"
                     /label="PKSI-AT-mM_m5"
                     /locus_tag="IE198_RS34105"
                     /protein_end="1758"
                     /protein_start="1745"
                     /score="3.4"
                     /tool="antismash"
                     /translation="GRNGPRATTVAGD"
     CDS_motif       10690..10716
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0023"
                     /evalue="1.70E+00"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="IE198_RS34105"
                     /protein_end="1791"
                     /protein_start="1782"
                     /score="2.5"
                     /tool="antismash"
                     /translation="VASHCAQVD"
     CDS_motif       10774..10800
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0024"
                     /evalue="1.80E+00"
                     /label="PKSI-AT-mM_m7"
                     /locus_tag="IE198_RS34105"
                     /protein_end="1819"
                     /protein_start="1810"
                     /score="2.3"
                     /tool="antismash"
                     /translation="VPFYSTVTG"
     CDS_motif       10822..10869
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0025"
                     /evalue="9.60E-03"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="IE198_RS34105"
                     /protein_end="1842"
                     /protein_start="1826"
                     /score="8.9"
                     /tool="antismash"
                     /translation="LTAGYWFDNARRPVNF"
     CDS_motif       10912..10941
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0026"
                     /evalue="3.60E-01"
                     /label="PKSI-AT-mM_m9"
                     /locus_tag="IE198_RS34105"
                     /protein_end="1866"
                     /protein_start="1856"
                     /score="4.4"
                     /tool="antismash"
                     /translation="FVESSAHPVL"
     aSDomain        11221..11727
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34105_PKS_DH.1"
                     /evalue="3.50E-63"
                     /label="IE198_RS34105_PKS_DH.1"
                     /locus_tag="IE198_RS34105"
                     /protein_end="2128"
                     /protein_start="1959"
                     /score="204.8"
                     /tool="antismash"
                     /translation="HPLIGAVVRSAAGGDALLTGRLSLQTHPWLADHTAMGGALLPGAA
                     FVELALRAGDAVGCDRLNELTLEAPLVLPERGGVQVQVAAKAPDADGRSHVAVYARPEA
                     EADADPDEPWTRHATGLLDMADTAPDGSADPTAWPPPGAERIDLDSFYERAADAGYGYG
                     PAFQGL"
     CDS_motif       11305..11379
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0027"
                     /evalue="3.40E-07"
                     /label="PKSI-DH_m2"
                     /locus_tag="IE198_RS34105"
                     /protein_end="2012"
                     /protein_start="1987"
                     /score="22.8"
                     /tool="antismash"
                     /translation="WLADHTAMGGALLPGAAFVELALRA"
     CDS_motif       11695..11727
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0028"
                     /evalue="1.00E-01"
                     /label="PKSI-DH_m3"
                     /locus_tag="IE198_RS34105"
                     /protein_end="2128"
                     /protein_start="2117"
                     /score="6.1"
                     /tool="antismash"
                     /translation="GYGYGPAFQGL"
     aSDomain        12673..13215
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34105_PKS_KR.1"
                     /evalue="4.30E-62"
                     /label="IE198_RS34105_PKS_KR.1"
                     /locus_tag="IE198_RS34105"
                     /protein_end="2624"
                     /protein_start="2443"
                     /score="201.2"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GTVLITGGTGALGGLLARHLVTEHGVRHLLLTSRRGKEAHGTAEL
                     VAELTESGAEHVEVAVCDAADREALAAVLAAVPAERPLTGVVHAAGVLDDGMLTSLTAE
                     RTQRVLRPKIDGALNLHELTRGLELSAFVLFSSIAGTFGNPGQANYAAANAFLDALAQH
                     RRAQGLPAHALAWGLWAE"
     CDS_motif       12676..12777
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0029"
                     /evalue="1.80E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE198_RS34105"
                     /protein_end="2478"
                     /protein_start="2444"
                     /score="30.2"
                     /tool="antismash"
                     /translation="TVLITGGTGALGGLLARHLVTEHGVRHLLLTSRR"
     CDS_motif       13006..13035
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0030"
                     /evalue="9.10E-02"
                     /label="PKSI-KR_m3"
                     /locus_tag="IE198_RS34105"
                     /protein_end="2564"
                     /protein_start="2554"
                     /score="6.7"
                     /tool="antismash"
                     /translation="PKIDGALNLH"
     CDS_motif       13063..13167
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0031"
                     /evalue="1.70E-22"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE198_RS34105"
                     /protein_end="2608"
                     /protein_start="2573"
                     /score="72.0"
                     /tool="antismash"
                     /translation="AFVLFSSIAGTFGNPGQANYAAANAFLDALAQHRR"
     aSDomain        13534..13749
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34105_ACP.2"
                     /evalue="3.10E-30"
                     /label="IE198_RS34105_ACP.2"
                     /locus_tag="IE198_RS34105"
                     /protein_end="2802"
                     /protein_start="2730"
                     /score="96.3"
                     /tool="antismash"
                     /translation="LDLVRAQVATVLGHADSSTIAASRPFQEIGFDSLTAVELRNRLSA
                     AVGQRLPATLVFDHPTPALITEYLRVE"
     aSDomain        13825..15096
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34105_PKS_KS.3"
                     /domain_subtypes="Modular-KS"
                     /evalue="3.70E-182"
                     /label="IE198_RS34105_PKS_KS.3"
                     /locus_tag="IE198_RS34105"
                     /protein_end="3251"
                     /protein_start="2827"
                     /score="597.9"
                     /tool="antismash"
                     /translation="IAIVGMACRYPGGVGSPDDLWRLVEDGGDAVSFFPTDRGWDDGLY
                     DPDPDSAGKTYAREGGFLYDAGEFDADFFGISPREALAMDPQQRLLLETSWEVFERSGM
                     DPTTLRGSSTGVFTGVMHHDYGADSETPAGLEGYAVTSTQGSVASGRIAYTFGLEGPAV
                     TVDTACSSSLVALHLAVQALRSGECSLALAGGVTVMATPWVFVEFSRQRGMAPDGRCKA
                     FSAAADGAGWSEGVGVLLVERLSDARRNGHQVLAVVRGSAVNQDGASNGLTAPNGPAQQ
                     RVIRAALAGAGLSSADVDVVEAHGTGTTLGDPIEAQAVLATYGQDRPADRPLRLGSIKS
                     NIGHAQAAAGVAGVIKMVQAVRHGVLPRTLHADEPSPHVDWSAGAVELLTERADWATDG
                     RPRRAGVSSFGISGTNAHVIIEEAP"
     aSModule        13825..18996
                     /complete
                     /domains="nrpspksdomains_IE198_RS34105_PKS_KS.3"
                     /domains="nrpspksdomains_IE198_RS34105_PKS_AT.3"
                     /domains="nrpspksdomains_IE198_RS34105_PKS_DH.2"
                     /domains="nrpspksdomains_IE198_RS34105_PKS_KR.2"
                     /domains="nrpspksdomains_IE198_RS34105_PKS_PP.1"
                     /locus_tags="IE198_RS34105"
                     /monomer_pairings="mmal -> Me-ccmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       14077..14103
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0032"
                     /evalue="9.20E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="IE198_RS34105"
                     /protein_end="2920"
                     /protein_start="2911"
                     /score="6.2"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     CDS_motif       14302..14349
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0033"
                     /evalue="2.60E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE198_RS34105"
                     /protein_end="3002"
                     /protein_start="2986"
                     /score="19.4"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     CDS_motif       14491..14529
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0034"
                     /evalue="3.10E+00"
                     /label="PKSI-KS_m4"
                     /locus_tag="IE198_RS34105"
                     /protein_end="3062"
                     /protein_start="3049"
                     /score="2.0"
                     /tool="antismash"
                     /translation="FSAAADGAGWSEG"
     CDS_motif       14725..14769
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0035"
                     /evalue="1.30E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE198_RS34105"
                     /protein_end="3142"
                     /protein_start="3127"
                     /score="11.3"
                     /tool="antismash"
                     /translation="VEAHGTGTTLGDPIE"
     CDS_motif       14830..14874
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0036"
                     /evalue="6.10E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE198_RS34105"
                     /protein_end="3177"
                     /protein_start="3162"
                     /score="9.5"
                     /tool="antismash"
                     /translation="GSIKSNIGHAQAAAG"
     CDS_motif       15442..15495
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0037"
                     /evalue="1.20E-08"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE198_RS34105"
                     /protein_end="3384"
                     /protein_start="3366"
                     /score="26.7"
                     /tool="antismash"
                     /translation="FVFPGQGSQWQGMAAELL"
     aSDomain        15445..16338
                     /ASF="Methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34105_PKS_AT.3"
                     /evalue="7.30E-104"
                     /label="IE198_RS34105_PKS_AT.3"
                     /locus_tag="IE198_RS34105"
                     /protein_end="3665"
                     /protein_start="3367"
                     /score="339.2"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGSQWQGMAAELLETSPVFAARLAECDAALRPYTGWSVTDA
                     VRGGQGAPPLDDVVVVQSALWAVMVSLAAQWQSLGVRPDAVIGHSQGEIAAAAVSGALS
                     LDDAAKVVSLRAQAIARNLSGRGGMVSVPLRADDVRERLARWGERISVASVNGPRSTVV
                     SGEPEALDELLAACEADEVPARRIPVDYASHSAQVEAIREEVLAALADIEPRCGEIPFY
                     STVTGGLFDTSGADAEYWYTNLRQEVRFDETVRALLTDGFGFFVESSARPVLTIGLEET
                     FEDTGSRAVALGTLRRD"
     CDS_motif       15607..15678
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0038"
                     /evalue="1.50E-05"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="IE198_RS34105"
                     /protein_end="3445"
                     /protein_start="3421"
                     /score="17.9"
                     /tool="antismash"
                     /translation="LDDVVVVQSALWAVMVSLAAQWQS"
     CDS_motif       15682..15792
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0039"
                     /evalue="4.70E-17"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="IE198_RS34105"
                     /protein_end="3483"
                     /protein_start="3446"
                     /score="53.9"
                     /tool="antismash"
                     /translation="GVRPDAVIGHSQGEIAAAAVSGALSLDDAAKVVSLRA"
     CDS_motif       15901..15939
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0040"
                     /evalue="3.90E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE198_RS34105"
                     /protein_end="3532"
                     /protein_start="3519"
                     /score="10.6"
                     /tool="antismash"
                     /translation="ASVNGPRSTVVSG"
     CDS_motif       16009..16041
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0041"
                     /evalue="1.40E-03"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="IE198_RS34105"
                     /protein_end="3566"
                     /protein_start="3555"
                     /score="11.5"
                     /tool="antismash"
                     /translation="VDYASHSAQVE"
     CDS_motif       16099..16125
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0042"
                     /evalue="2.40E+00"
                     /label="PKSI-AT-mM_m7"
                     /locus_tag="IE198_RS34105"
                     /protein_end="3594"
                     /protein_start="3585"
                     /score="2.0"
                     /tool="antismash"
                     /translation="IPFYSTVTG"
     CDS_motif       16150..16194
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0043"
                     /evalue="4.00E-04"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="IE198_RS34105"
                     /protein_end="3617"
                     /protein_start="3602"
                     /score="12.9"
                     /tool="antismash"
                     /translation="DAEYWYTNLRQEVRF"
     CDS_motif       16237..16266
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0044"
                     /evalue="2.30E+01"
                     /label="PKSI-AT-mM_m9"
                     /locus_tag="IE198_RS34105"
                     /protein_end="3641"
                     /protein_start="3631"
                     /score="-0.6"
                     /tool="antismash"
                     /translation="FVESSARPVL"
     aSDomain        16540..17052
                     /ASF="catalytic triad H,G,P found: False"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34105_PKS_DH.2"
                     /evalue="9.60E-63"
                     /label="IE198_RS34105_PKS_DH.2"
                     /locus_tag="IE198_RS34105"
                     /protein_end="3903"
                     /protein_start="3732"
                     /score="203.4"
                     /tool="antismash"
                     /translation="HPLLGAVVSLPDDRGALWTGRLSLAEQPWLADHAVFGSVVLPGAV
                     LVELALQAGGRVACGRLEELTLQQPLVLGDAGGVRLQVAVTGADEAGRRAVTVHSCPDG
                     GGADEAVPGGETWTLHATGTLVDGGGPFAAADLAAWPPRGAEKVDVSDLYDRLADQGYG
                     YGPAFQGV"
     CDS_motif       16624..16701
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0045"
                     /evalue="6.70E-10"
                     /label="PKSI-DH_m2"
                     /locus_tag="IE198_RS34105"
                     /protein_end="3786"
                     /protein_start="3760"
                     /score="31.4"
                     /tool="antismash"
                     /translation="WLADHAVFGSVVLPGAVLVELALQAG"
     CDS_motif       17020..17052
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0046"
                     /evalue="9.90E-02"
                     /label="PKSI-DH_m3"
                     /locus_tag="IE198_RS34105"
                     /protein_end="3903"
                     /protein_start="3892"
                     /score="6.1"
                     /tool="antismash"
                     /translation="GYGYGPAFQGV"
     aSDomain        17920..18456
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34105_PKS_KR.2"
                     /evalue="7.20E-58"
                     /label="IE198_RS34105_PKS_KR.2"
                     /locus_tag="IE198_RS34105"
                     /protein_end="4371"
                     /protein_start="4192"
                     /score="187.5"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GTVLVTGGTGGLGALVARHLVSAYGVRDLLLVSRRGKAADGVDAL
                     VAELNRSGARVRVEACDVSDRAALATLLASVPQDRPLTGVVHSAAVLDDGVIEALDAER
                     LAGVFRPKTDAALHLHELTAGLGLSAFVLFSSFAGVVGSAGQAGYAAANVFLDALAHER
                     RAQGLPAVSLAWGWWG"
     CDS_motif       17923..18024
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0047"
                     /evalue="2.20E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE198_RS34105"
                     /protein_end="4227"
                     /protein_start="4193"
                     /score="26.7"
                     /tool="antismash"
                     /translation="TVLVTGGTGGLGALVARHLVSAYGVRDLLLVSRR"
     CDS_motif       18250..18279
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0048"
                     /evalue="4.10E+00"
                     /label="PKSI-KR_m3"
                     /locus_tag="IE198_RS34105"
                     /protein_end="4312"
                     /protein_start="4302"
                     /score="1.8"
                     /tool="antismash"
                     /translation="PKTDAALHLH"
     CDS_motif       18307..18411
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34105_0049"
                     /evalue="1.20E-17"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE198_RS34105"
                     /protein_end="4356"
                     /protein_start="4321"
                     /score="56.5"
                     /tool="antismash"
                     /translation="AFVLFSSFAGVVGSAGQAGYAAANVFLDALAHERR"
     aSDomain        18742..18996
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34105_PKS_PP.1"
                     /evalue="1.90E-31"
                     /label="IE198_RS34105_PKS_PP.1"
                     /locus_tag="IE198_RS34105"
                     /protein_end="4551"
                     /protein_start="4466"
                     /score="100.2"
                     /tool="antismash"
                     /translation="AGLSEAERERVVLDLVRGHVSGVLGYGPGRLVDLETPFKALGFDS
                     LMAVELRNRLNRATGLRLPASLVFDHPTVQELTRYVVTRL"
     aSDomain        19036..19293
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34105_PKS_Docking_Cterm.
                     1"
                     /evalue="1.30E-12"
                     /label="IE198_RS34105_PKS_Docking_Cterm.1"
                     /locus_tag="IE198_RS34105"
                     /protein_end="4650"
                     /protein_start="4564"
                     /score="40.4"
                     /tool="antismash"
                     /translation="PILADLGKVEQALTGTDLGGDARQRIAERLMDLLTLSGPEGDPVG
                     PLTQADPGTDGEDGGGTAFVDQLEAATPDEILDVIEKEFGN"
     gene            19351..>20693
                     /locus_tag="IE198_RS34110"
     CDS             19351..>20693
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (10-31). E-value:
                     4.4e-06. Score: 18.2. Matches aSDomain:
                     nrpspksdomains_IE198_RS34110_PKS_Docking_Nterm.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (35-448). E-value:
                     7.7e-175. Score: 573.8. Matches aSDomain:
                     nrpspksdomains_IE198_RS34110_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014057311.1"
                     /locus_tag="IE198_RS34110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I polyketide synthase"
                     /protein_id="WP_189893845.1"
                     /sec_met_domain="mod_KS (E-value: 3.5e-222, bitscore:
                     726.4, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.2e-94, bitscore:
                     305.2, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDNKNLLGTLKRVARELHETRRQLQDSERRRSEPVAIVGMACRY
                     PGGVGSPEDLWQLVAHAGEAVSDFPDDRGWDTDALFDPDPDRPGRSATRKGGFLYDAAE
                     FDAGFFGISPREALAMDPQQRLLLEVSWEAIERSGMDPKSLKGSRTGVYAGVMYHDYAA
                     GLPTVPDEIEGYYGTGTAASVVSGRVPFTLGLTGPAITVDTACSSSLVALHLAVQALRR
                     DECSLALAGGVSVMSSPVMFAEFSRQGGLSADGRCKAFGAGADGTGWSEGVGVLVLERL
                     SDARRNGHQVLAVVRGSAVNQDGASNGLTAPSGPAQERVIREALADADMSAETVDAVEA
                     HGTGTRLGDPIEAQALLATYGQGRGEEQPLWLGSLKSNLGHAQAAAGVGGVIKMVMAMR
                     HGVLPRTLHVGEPTPLVDWDAGAVELLGEAREWPEVEGRPRRAGVSSFG"
     aSDomain        19381..19443
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34110_PKS_Docking_Nterm.
                     1"
                     /evalue="4.40E-06"
                     /label="IE198_RS34110_PKS_Docking_Nterm.1"
                     /locus_tag="IE198_RS34110"
                     /protein_end="31"
                     /protein_start="10"
                     /score="18.2"
                     /tool="antismash"
                     /translation="LKRVARELHETRRQLQDSERR"
     aSDomain        19456..>20693
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS34110_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="7.70E-175"
                     /label="IE198_RS34110_PKS_KS.1"
                     /locus_tag="IE198_RS34110"
                     /protein_end="448"
                     /protein_start="35"
                     /score="573.8"
                     /tool="antismash"
                     /translation="VAIVGMACRYPGGVGSPEDLWQLVAHAGEAVSDFPDDRGWDTDAL
                     FDPDPDRPGRSATRKGGFLYDAAEFDAGFFGISPREALAMDPQQRLLLEVSWEAIERSG
                     MDPKSLKGSRTGVYAGVMYHDYAAGLPTVPDEIEGYYGTGTAASVVSGRVPFTLGLTGP
                     AITVDTACSSSLVALHLAVQALRRDECSLALAGGVSVMSSPVMFAEFSRQGGLSADGRC
                     KAFGAGADGTGWSEGVGVLVLERLSDARRNGHQVLAVVRGSAVNQDGASNGLTAPSGPA
                     QERVIREALADADMSAETVDAVEAHGTGTRLGDPIEAQALLATYGQGRGEEQPLWLGSL
                     KSNLGHAQAAAGVGGVIKMVMAMRHGVLPRTLHVGEPTPLVDWDAGAVELLGEAREWPE
                     VEGRPRRAGVSSFG"
     CDS_motif       19711..19737
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34110_0001"
                     /evalue="5.20E-03"
                     /label="PKSI-KS_m2"
                     /locus_tag="IE198_RS34110"
                     /protein_end="129"
                     /protein_start="120"
                     /score="9.6"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     CDS_motif       19939..19986
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34110_0002"
                     /evalue="1.80E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE198_RS34110"
                     /protein_end="212"
                     /protein_start="196"
                     /score="22.8"
                     /tool="antismash"
                     /translation="GPAITVDTACSSSLVA"
     CDS_motif       20362..20406
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34110_0003"
                     /evalue="6.60E-05"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE198_RS34110"
                     /protein_end="352"
                     /protein_start="337"
                     /score="14.7"
                     /tool="antismash"
                     /translation="VEAHGTGTRLGDPIE"
     CDS_motif       20467..20511
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS34110_0004"
                     /evalue="1.50E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE198_RS34110"
                     /protein_end="387"
                     /protein_start="372"
                     /score="11.2"
                     /tool="antismash"
                     /translation="GSLKSNLGHAQAAAG"
ORIGIN
        1 gcgtgccgat cagcggacgc tcggcctccg cgagggcggc ggccgggacg tccttcaact
       61 gctcctttga ggccttctcc tcgccctcca tggtcttgcc gccgccggcc agcaggtagg
      121 gggccttggc gtgtgcgtgg tcgcgcagcg acatgatcag cagcttcggg gacagcggct
      181 tgccggtgtt ccaggcgggg cactgtgact ggcagcggcc gcactcggtg caggtggaga
      241 agtcgaggat gcccttccag gagaactgct cgacctggga gacaccgaag gtgtcgtcct
      301 cgcccgggtc ctcgaagtcg atctccttgc cgcccgacgt catcggcttc agctcgccga
      361 gagcggactc accggtcgcg ttgcgcttga accagatgtt cgggaagccg aggaagcggt
      421 gccaggccac acccatgtcg gtgttgaggg agatggtgat cgcccagatc atggtggtgc
      481 cgagcttcac catggcagcg aggtaggtga ggttctgcag cgttgagacg tcgaggtcat
      541 ggaaggcgac gaccaggggg tacgaggcga agtacgcggc ctcgtagtgg tcgacgtggt
      601 ggatcgcacc ctcgagcccg cgcagggtca tgatcgccag accgatgacg acgatgacgt
      661 actcgacgaa gtacgcctgc caggccgtgg agccggcgaa gcgggacttg cgaccggccc
      721 gggagggcag gttgagctgc cggatcgcga tcaggacgat gattcccacc gtcgtcccga
      781 gcgcgatgaa ctccgtgtac agctcgtacg gcagccatcc gcccaaaatc ggcagcacga
      841 agtcggcctt gaacagctgg cagtacgccg tgaggatggt caggcccagg gtgaggaagc
      901 cgacggcgac gaaccagtgg gcaatgccga cgatgcccca ccggttcatc cgggtgtggc
      961 cgatgaactc cttggccagc gtcacgctgc gcgcctgcca gttgtccgtg cggctgcccg
     1021 cagggacagg ctgacccagc ctgacgaacc ggtagatctg cgcgacggct cggccgatca
     1081 gtgcgacacc gagcacggtg agcaccaacg acacaatgat cgcggtgagt tgcatgaggg
     1141 ctcctcggac ctgcgagagc ggggatttgc ggattactaa gcggtaactt tgctttcagg
     1201 gtgacattac ccacggccgc aggccccatg aaggcgcacg gctggtgatc tgtgtcgctg
     1261 agggcgccct ggctctgcac cggagcgccg tcagcgcatc tcatggcccg gatcgcaggt
     1321 gtcggtacgc gccccaacgg cgtgagcagc acgacggctc ggaccgtacg gcggatgacc
     1381 tcagcgggcc cccgcggtct ctgtctgcga ggagccggca agtgacccgt ggacgagtag
     1441 ttgcacgatc tccatcagct gcgggtggtg cggtcggtag tcggggttgc gggagcgggc
     1501 gaagagcaga tcgaagaagg cctgggctat gtgcggcgcc ggcagccgca gggactcctc
     1561 ctccgggccc aacagggccg cgagagaggc gacgacggag tcgaaggctt cgcggacctc
     1621 ccgcattccc ccggcggagg cggcggagta ccgccgtgcg cggccgtggc ctcctgcctc
     1681 caagtaggtg atcaccgtgc cgacacgcgt caggtacgcc tccagtactc cggcagccgc
     1741 gacgagtcgc gctgtcacgg gggcgtccaa gggaatgtcg gcaagctcgt acacgacgtc
     1801 gtcggagcgt gctgcctcgg ccatacaggc atccagcaac tcgtccttgt cgctgaacac
     1861 atgaaagatc gttgcctcgc tgatggcggc agcgcgggcg atcctgccgg tggtcacagc
     1921 cgggccgtgt tccgtgatca gtgagagtgt ggatcggacg atcatctggc ggcgtagttc
     1981 cgggctcatg ctcggagccc gccgccgccc gggagtcggg ccggtcatag gccaatgtta
     2041 ctgatcagtt gctaacttgg tcaaacgtgt gtcccggcat cccggcgacc caccgctgct
     2101 cgaactgcgc gccctcgccc cttgtccggt acccgagggc gtcgtccggt cgatacccga
     2161 cgacgcctgc tcgggccccg cgccggcccc ctccgccgga tcagtggagg gggacggcag
     2221 cgggcacggt tgctcgtgtg caggggcgac gggcagtgcg cccgatgccg gatcagaccg
     2281 tctggtagcg cccggtcggc cggggcagac tcagccggtc gcgcagggtg gccccgccct
     2341 gagctgcctg ctcagcgggg ccgtccgctc gcactgcggc cgcgagggca atcacggcct
     2401 cgtgcgccgt gcctgccgcg ccgtcggggg cgagcagggt gaagccgtcc gcgacgcccg
     2461 cgtcgaagag ttcccgcagc cggccggccg cgtctgcgct gccgtcgacc ggccagtcga
     2521 gcagcaccgc gacgtcgtcc gggtcgcgtc cggccgcccg gacctgatca cggaccgact
     2581 cccggagaag gacggggtcc tggccgttcc gtgccgggag aaggacgaca tcggcggcgc
     2641 gggcggcgag cgcgaagtcg tcgccgtccg cggcgcgatg gaccagggga gggtgcccct
     2701 gcggtggacg ggcgatgttc agcggcccgg ccacgtcgaa gcactcaccc ttgtggtcga
     2761 gcgtgtgaag cttctcgggg gtgaagtaga cacccgactc gcggtccctg cggaaggcgt
     2821 cgtcgtcgaa gctgtcccac aggccggtca gtacggtgac gaactccgaa gcccgggcgc
     2881 gccgtgccgc cgccgactcg gtgccggacc ggctgtagtt ggccgacgcg tcggggtcgg
     2941 ccgtggtgat cggctgccag ccggcgcgtc cgagggtgat gtggtcgatc gtggccaggg
     3001 tccgtgccac gtggtagggc agggcgtact cggtggagac ggcggccacg agccccacgg
     3061 tgcgcgtgcg gaccgccagg gcggctgcga gggtgccggc ctcgaaggag ggatcgccgg
     3121 ccgggtcgtg agaggccgac tgccggtcgt ggagcagtag cgcgtcgatc ccggcgtcct
     3181 ccgccgcccg ggccctgtcg aggacccgcg cgaaggcgcc cgcgtcggcg gcctgcgagt
     3241 caccgcacgt ggtctccggg gcggtgaaca gctgtgtgaa caaggtgatg tgaccaccgc
     3301 ggcggctcat gcggcacctg cctggagcgc cggttcgccg gttctcgtcg caccgtcgga
     3361 gcaaggagcg accagcccca acttctcgcg cagggtgccg tcggtgtact cgtcctgcac
     3421 cagcccgcgc cggcgcagct caggcaccac atggtcgacg aatgcatcga gtgaggaggg
     3481 caggtggggg aagtccacga cgtagccgtc ggcggcacgc tcggtgaacc cgcgctccag
     3541 gtggtccgcc acctgctccg gcgtaccggc gaagaagtcg gcgacctggc gcagggcgag
     3601 ttggcgcagt gtcaggttct cccggtgcgc cagcgacgtc cacatcctcc tcgtgctgga
     3661 ggagcggttg gaggtcggaa tgtccgggac cggcccatcg aggggatagc gcgtcaggtc
     3721 caggtcgccc agctgctcct gaagcgcccg gatggccacg atgtcgggta cgaggtcgtg
     3781 cagttcattg atgaggcggc gcgcctcctc ctccgtgccg gccacgaggg gttggacacc
     3841 gggccagatc tggacccgtt ccgggtccct gccgtgtgcg gtgacccgtc gcttcaggtc
     3901 cgcgtaggtc tcctggccgt ccgacagttg cgtgtgccgg gtgaagatca cctccgcatg
     3961 ccgtgcggcg aactcgcggc ccacgggcga ggctccggcc tggaagatca cgggactgcc
     4021 ctgaggggag gccggcaggt tcagcgggcc ctggacgtcg aagaactcgc cgcagtgcgc
     4081 gtgccgtgac tcccgagcgg cgccggcctg gggccctgtg gcccacagcc gtttggtcac
     4141 gccgatgaac tcctcggcgc ggacatagcg ccggtcgtgc tccatgtgct cggggtggcc
     4201 gaagttacgc gactcccagg gggctgcgga agtgacaacg ttccacccgg ctcggccgcc
     4261 gctgatgcgg tcaagggacg tgaacctgcg ggcgatgtcg tacggctcgt tgtaggtggt
     4321 cgtcgcggtc gacgcgagcc cgatgtggtc ggtcccggcc gcgtaggcgg ccagcaggct
     4381 cagcggctcg aagtgctcgt tgcgtgcggt cttgctgatg tgctcgacgt cggtgcccca
     4441 gagggccacc acgtcgggca cgaagaggca gtcgaacatg ccccgctcga gtgtgcgagc
     4501 gcacgccagg tggaaggcga agtcgagttg ggcgtcgacc ggagtggacg gatgccgcca
     4561 ggcggcgatg tgcgagccgg ggccgtcgat gatggccccg agcctcatcg tgcgtttctg
     4621 atgaaccata cgatcttccc tccgctggag ttttctgatg acgggacttc cgcagggaac
     4681 tcgcctctcc gctgccgttc cgagaggtta ctgcggatcg accgtactag gtgattgagc
     4741 gcctgtccgg tccatatgag gcatggggtt ctgagcgcgc agaaattcac tgcaggtatg
     4801 gagagcggcg ggtgaggtat ccaagccggt cgtcccgggt gcttcgtccg cgcacgtagt
     4861 cgctgcgtgg atcggtctct ctgtgttgct gaaacccagc tgaaaccgca gcatgacata
     4921 ctggccagta atcggcggga tgtgctagcg atgcaatgtt gatcagtggc ttgtgaagcg
     4981 gtctttcttg gtaaacgtgg gcagttttca tcgggggggc atggtggcgt gttctgatgc
     5041 ggagaacgcg gtcgcgctga ggccggccgt gcccgcggtc ggccgtggcc aggcgggtac
     5101 ggtcccctgt gtgcgcagcg tggcaacggc cgacggatgt gccggccgca gcttcgggaa
     5161 acgcctgaga aggtttgtgt gacgcctcgc ccgatctgtg tctgccgtca atcggccgtc
     5221 ccggatcggt gattccagcg gtgcagtccc ggcaaagtgt gaagtccttc tggattctgt
     5281 gtgtgatgtg acccggcctg tgtgcgtgca cgtttttctg gtatttcttg aaggggtatc
     5341 gccgtgagtg gtgaagctgt ttccgagcgt ggcggtcgaa acgccggtgc agaaatcgcg
     5401 gtcgtcggat tctcatgcag agttgccggc gcggcgactc ccgacgagtt ctggcagctc
     5461 ctgaaagacg gtcgttctga ggtaaaggaa ttccccgtcg cccgacgggc cgatcagggc
     5521 ccggactttc ccgacctgcc aggcggctac ctggagagcg tggacgggtt cgacgcggat
     5581 ctcttcgagg tgtcaccggc cgaagcggcc gcgatggacc cccagcagcg cttggcgctg
     5641 gagctgagct gggaggcggt ggagcacagc ggcgcttctc cggacgccct gcggggcacc
     5701 cggaccggcg tcttcgtcgg ggccatcaac gacgactacg ccgcactgct gcaccaccgg
     5761 ggaacgggct cggtgacacg ccacagcctg acgggcactc agcgcagctt catcgccaac
     5821 aggatctcct accgcctcgg cctgcgcggg cccagcgtcc tggtggactc cggccagtcc
     5881 tcctccctcg tcgcggtgca tctcggggtg cagagcctgc tgcgtggcga gtccgacgcg
     5941 gtactggcgg gaggtgtgaa cctcatcctc tcggagcaca gcaccagcag tctcaagcac
     6001 ttcggcgccc tctcgcccga cggccgctgc tacaccttcg atgcacgcgc caacggctat
     6061 gcgcgaggcg agggcggcgg attcgtgctg ctgaagtccc ttgagcgggc cgtcgccgac
     6121 ggtgaccggg tcctggcagt catcgaaggc agtgccgtca acaacgacgg cggcggtgac
     6181 ggcctgacgg tccccagcgc cgcggcccag cacgaactgc tgcgggacgc gtgcgacgcg
     6241 gccggtatgt cgcccgccga catccagtgc gtcgaactgc acgggacggg caccaaggtc
     6301 ggggacccac tggaggcttc tgccatcggg caggcgctcg gcgccgaacg ctccgacgac
     6361 aggcccgtac gggtcggttc cgtcaagacg aacatcggcc acctggaggc ggcggccggg
     6421 atcgtcggac tgctgaaggt cgtctcctgc gtcagccgtc gcgagctcgt ccccactctc
     6481 aaccaggaga ccgggaaccc gcgcatcccg ttcaccgagt ggaacctcga ggtacagcgc
     6541 gcacacgagc agtggagagg cgagaacggc cggctcatcg ccggtgtctc ctccttcggg
     6601 ctgggcggca cgaactgcca cgtggtcatc ggtgacccgc ctcctgagct gcgcggcgga
     6661 caccagggcc agagcggcca agccggtcac ggtggggaaa gcccctcgga gccggtacct
     6721 acttcgccca cgacgcgggg ccccgtcccc tggccgatct cggcccgcgg cgaggcagcg
     6781 ctgcgcggac aggcggagca gctggacacc catgtgcggc agcgcccgga ggccgatgtc
     6841 cacgccgtcg gccgcgggct ggcggcgggc cgggcgcggt tcgagcaccg ggccgtcgtc
     6901 gtgggcgagg acggcccgag cctgcgtgcc ggcctccggg cggtgtcggc gggtgccggt
     6961 gccgcgaacg tggtccgcgg tgtggccggt gactcgcgtg ctgatgggga tgccgaagca
     7021 cagagcggag tggtgttcgt cttccccggc cagggggcgc agtgggcggg catggcggtg
     7081 ggactcctcg aatcgtcccc ggtcttcgcg gagcggatgg cggcgtgcga ggcggcgctg
     7141 tcgccgtacg tcgagtggtc gttggcagag gtggtacggg acctggccga tgcgagccgg
     7201 ctcgaccgcg tcgatgtggt gcagccggtg ttgtgggcgg tgatggtgtc cctcgcggag
     7261 gtgtggcggt cgacgggcgt cgagccggcc gcggtggtgg ggcactccca gggcgagatc
     7321 gcggcagcag tggtggcggg agtcctctct ctgtcggacg gtgccagggt ggtggcgctg
     7381 cgcagccggg cgatccggca ggacctgtcc gagcggggtg gcatggtcgc ggtctcgacg
     7441 ggagccgcag cggcggcaga gctgatcgcc gagttcggcg ggcagctgtc ggtcggtgct
     7501 gtcaacggcc cgtcgtcgac ggtcgtgtcc ggcgcaccac gagcgctgga ggagttgttc
     7561 gcccgctgcg agtccgaggg gatcagggcc cgcagggtgc cggtcgacta cgcgtcgcac
     7621 tgcgccgagg tcgaggtcgt ccgcgacgag gtgctgcgcg aactgaccgg gatcacgccc
     7681 gcgcgggcgg aggttcctta ctactcgacg gtgaccggtg gaccggtcac cgggagcgag
     7741 ttggacgctg agtactggta caggaacctg cgccagacgg tgcgattcga ggagagcgta
     7801 agggccgcgg tcgcggacgg gttcacccgt ttcgtcgagg tgagtgccca cccggtcctc
     7861 gtgacagggg tggaggaaac actcgaagcg gccggtgtgg gcgaacacgg cctggtgctc
     7921 ggcacgctcc gccgcgacga gggcggctgg gaccgtttcc tgctgtctgc cgccgaggcg
     7981 tggacccgcg gcgtcgacgt ggactggagc gcgctgctgg gcccggggcc cagggcgacc
     8041 ggcctgccga cgtacgcctt ccagcgccgg cggcactggc tggacacggc tgcccggagc
     8101 cggactgtga ccgagcccga aggcaccaca gcccaagggg cacgggcggg gggaccggag
     8161 caggaggtgc aggctcccgc aggtgatgtc acacccgagc gggtggcgga tctcgtacgg
     8221 gacgaggtcg ccgtcgtact cggacactcg tcgtcccacg acatcgacat gggccgtacg
     8281 ttcaaggcgc tcggcttcga ctccgtggcg atggtcgacc tgcgtaaccg gctcagggca
     8341 gcgaccggtg tcaacctgac cacgacggcc ctcttcgacc accccacacc gtccgcgacc
     8401 gcgactcacc tcaggagccg gctgctcgga ctcgacgagg cagcggccga ggggcccgcc
     8461 gagcgggccg ccggcggcgc cgacgacgag ccgatcgcga tcgttgcgat ggcatgccgc
     8521 ttccccggcg gtgtggagac gcccgaggac ctctgggacc tgttgatcgc cgagcgggac
     8581 gtgatcgggg acttccccgt gaaccgcggc tgggacctgg agaacctgta cgacccgcag
     8641 tcggagcggc acggtacgag ctatgtgcgg cacggcgggt tcctgcacga cgcgggcgag
     8701 ttcgacgcgg acttcttcgg gatctcgccg cgcgaggcgc tggccatgga tccgcagcag
     8761 cggctgctcc tggagacgtc ctgggaagcg ctggagcggg ccgggctgga tccgtcgtcg
     8821 ctgcgcggca gccggaccgg tgtgttcctc ggcgcgatgt tccaggagta cgggccgcaa
     8881 cttcagcacg gctcggagga agtcgccggg caccggctga ccggcggcac gatcagtgtg
     8941 gcttcgggcc gcgtggcgta caccctgggc ctggaaggcc ccgctgtcac cgtggacacc
     9001 gcctgctcct cctccttggt cgccctccac tgggcggtgc ggtcgctgcg atcgggcgag
     9061 tgctcgatgg cgctcgcggg cggcgtgacg atcatgccga cgcccggcat gttcgtggag
     9121 ctcagccgcc agggcgccct gtccccggac gggcggtgca aggcgttctc gtcgacggcc
     9181 gacggcaccg gatgggcaga gggtgtgggc gtccttctgg tggagcgcct gtcggacgcc
     9241 cgccgcaacg gtcaccaggt gctcgccgtc gtacgcggta gcgccaccaa ccaggacggc
     9301 gccagcaacg gcctcaccgc cccccacggt ccggcccagc agcgcgtcat ccgcgccgcg
     9361 ctggccgacg cgggcctcac gcccgacgac gtcgacgtcg tcgaggcgca cggcacgggc
     9421 acgcagctcg gtgacccgat agaggcgcag gctctgctgt ccacgtacgg gcagaggcgc
     9481 ccgggaagcc ggccactgcg gctggggtcg gtgaagtcga acatcgggca cacgcaggcg
     9541 gcggcgggtg tggccggagt cataaagacg gtgatggcga tgcgccgcgg catgctgccg
     9601 cgcaccctgc acgtggccga gccgtcgccg cacatcgact ggaccgcggg cgccgtcgaa
     9661 ctgctcaccg aaccgcagaa gtggacggcg gacgggcgtc cgcgcagggc gggggtgtcc
     9721 tcgttcggca tcagtggcac caacgggcac gtgattctcg aagaggctcc tggcgacgcg
     9781 caggtccggt ccgcacgacc ggctgcggcc gacgcgagtg gcggcacggg ccttggggcc
     9841 gccggcggcc cggtgccgtg ggtggtgtcg ggcaggtcgg aggaggggct gagggcgcag
     9901 gccggacgtc tctctgcgtt cgcccgggcg cgcacggaca tgtccgcgct ggacatgggc
     9961 tggtccctcg cggcgtcgcg tgcggtccac gagcaccgcg ccgtggtgct gagggccgac
    10021 cgggacgcgg gcctggccgg cctgtcggcg ctggccggcg gacagcctgc cgcaggagtg
    10081 gtcaccggcg cggcggacgt ccgcggccgg gtcgtgttcg tctttcccgg ccagggctcc
    10141 cagtggcaag gcatggcggc cgagctcctg gattcctcag cggtgttcgc cgcccggctc
    10201 actgaagtgg acgccgcgct gggcaagttc gtggactggt cggtgaccga cgtactgcgc
    10261 caggagccgc acgccccctc tgccgagcgc atcgagatcc tgcaaccggt gctgtttgcg
    10321 gtgaacgtgt ccctcgccgc ggtgtggcag gcctccggcg tgcagcccgc cgcggtggtg
    10381 gggcacagcc agggcgagat cgccgccgcc catgtggcgg gggcgctgtc gctggaggac
    10441 gcggcgaagc tgatcgtgct gcgcagcggc ctgttcgccc gcgagctggt cggcaagggc
    10501 gcggtcgcct cggtggcact gcccgcggac gctgtggagg agcggctcac gccgtggcag
    10561 gaccggctgg tggtcgccgg gcgcaacggc ccgcgggcga cgacggtcgc gggcgacgtc
    10621 ccggcgctgg aggagttcgt ggcctcctgc aagaaggacg gggtcagggc acggatcgtg
    10681 ggatcgacgg tggcctcgca ctgtgcgcag gtcgaccccc tgcgcgagga gatcctggag
    10741 ctgttcgccg acatcacgcc ggtcaagggc agcgttccgt tctattccac ggtcaccgga
    10801 tccgtccgcg acggcgagga gctgacggcc gggtactggt tcgacaacgc ccggcgaccg
    10861 gtgaacttcg agggcaccgt gcggaccctc ctcgcggacg gattccggtt cttcgtcgag
    10921 tccagtgcgc acccggtgct gaccacgggc gtgcaggcga ccgccgagga agcggagata
    10981 gaggcggtgg cgatcggttc gctgcgccgt gacgagggcg gccccgcccg attcctgacg
    11041 tcgctggcgg agggatacgt acgagggctg cccggtgtgg aatggaaggc cctgttcgcg
    11101 ggggcggacg cgcggctgat tgagctgccg gtgtacgcct tccagcgccg ccgctactgg
    11161 ctggggacca cggccgaagg caccggcgat ccgcgccgcc tcggcctcgg cgccgcccac
    11221 cacccgctga tcggtgcggt ggtacggtcc gccgccggtg gggacgccct gctgacgggc
    11281 cgcctctcgc tgcagacgca cccttggctc gccgatcaca ccgcgatggg cggcgcgctg
    11341 ctgccgggcg ccgcgttcgt ggagcttgcc ctgcgcgcgg gcgacgcggt gggatgcgac
    11401 cggctcaacg agctcacgct cgaggccccg ctggtcctgc ccgagcgcgg cggcgtccag
    11461 gtgcaggtcg ccgccaaggc cccggacgcc gacgggcgca gccacgtggc ggtgtacgca
    11521 cggcccgagg ccgaggcgga cgcggacccc gacgagccct ggacccggca cgcgaccggc
    11581 ctcctggaca tggcggacac ggcaccggac ggctcggccg atccgacggc ctggccgccg
    11641 ccgggcgctg agcgcatcga cctggactcc ttctacgaga gggccgccga cgccggctac
    11701 ggctacgggc ccgccttcca gggcttgcga gccgcctggg gcgtcggcgg tgaggtctac
    11761 gccgaggtgg cccttggcga cgaacagagg accgatgccg gcaggttcgg catccacccg
    11821 gccctgctcg acgccgcgct gcaccccgcc ctgctgagcg cgctcgacga ccagcccccc
    11881 gtcctgcggc tgccgttcgc ctggcgcggc gtcgcactgc acgccgtggg cgccgcctcc
    11941 gcacgcgtac gggtggcccc cgccggtgcg gacgcggtgt ccgtgacgat caccgacgcc
    12001 accggcgcac cggtggcctc agtggattca ctgaccttgc gagcggtgtc tccgcggcag
    12061 ctcaccggcg cctcggacgc cggccgcaac gcgctgttcc gcaccgtgtg gacaccgctg
    12121 cccgatcccg gagccgcccg ggacaccagc ggcctggtcg tgctcggcac gccgcggacc
    12181 ggcctgttcg acacggccgg gcacgccccc gatctggcgg cgctgtacgc cgacggcgcc
    12241 gcaccggatg tcgtcgtggc cacctgcggc cctgcgggaa gggacctcgc ggccgccgcg
    12301 cacacggcga cgaccgacat gcagaggctc gcccaggcgt ggctctccga ggagcgcgcc
    12361 gcgcggagcg tcctcgtggt ggtgacccga ggagccgtgt ccgcgcggcc cggagaggac
    12421 gtcgtggacc tggcgcacgc cccggtgtgg ggcctgctgc ggtctgcgca gtcggagaac
    12481 cccggccgct tcctgctggt ggatgtcgac gacctcgacg cctcccgcga ggccctggcc
    12541 accgcggtca tgacggcggt ggccgcgcag gagccgcagc tcgcggtccg tgagggcacg
    12601 gccctggtgc cgcgcctgac ccgggccccg gcacccggac aggacgactc ccgggcatcg
    12661 ttcggcccgc acggcaccgt actgatcact ggcggcaccg gagccctcgg cggactgctc
    12721 gcccggcacc tggtcaccga gcacggagtg cggcacctgc tgctcaccag ccgccgtggc
    12781 aaggaggcgc acggcacggc cgaactggtc gcggagctca ccgagtcggg cgcggagcat
    12841 gtcgaggtcg cggtgtgcga cgcggccgac cgcgaggctc tggccgcggt cctggccgcc
    12901 gtcccagccg aacgaccgct gaccggcgtg gtgcacgcgg ccggcgtgct cgacgacggc
    12961 atgctgacct ccctgaccgc cgagcgcacg cagcgagtac tgcgcccgaa gatcgacgga
    13021 gcgctcaacc tgcacgaact gacccgcggc ctggaactgt cggcgttcgt cctgttctcc
    13081 tcgatcgcag gcaccttcgg caacccgggc caggccaact atgcggccgc caacgccttc
    13141 ctggacgccc tcgcccagca ccggcgcgcc cagggcctgc ccgcccatgc cctggcctgg
    13201 ggcctgtggg cggagtccgg cgacatgctc ggccatctcg ccgatcacga cctggcatgg
    13261 atgaagcgtg ccggtgtccg gccgctgccg tccgccgagg gcctggccct gctggacaca
    13321 gcggtcacgc gggacgaggc acacctgatc cccgtacgcc tggaaatggc caccctgcgc
    13381 accgaggcgg cctccggtat gttgcggccc cttttccgtg gcctggtacg gccgcagggc
    13441 cgcagggcca cccccaccgc agagagcacc gggggcacct cgctcgccca gcggctgtcc
    13501 ggcctggcca cgaacgaaca gagccgggtg ctcctcgacc tggtgcgtgc ccaggtcgcg
    13561 accgtcctgg ggcacgccga cagcagcacg atcgccgcga gccgcccgtt ccaggagatc
    13621 ggcttcgact cgctcaccgc ggtcgagctg cgcaaccgcc tgagcgcggc cgtcgggcaa
    13681 cgcctgcccg ccacgctcgt cttcgaccat cccacgcccg ccctgatcac cgagtacctg
    13741 cgcgtggagc tcctcggtgc cccgccggcg accacggccg tgccgccgcg gcccgtggtc
    13801 ccgggcggcg cggcggagga gccgatcgcc atcgtcggca tggcctgccg ctaccccggc
    13861 ggcgtcggat caccggacga cctgtggcgg ctcgtcgagg acggcggcga cgcggtgtcg
    13921 ttcttcccga ccgaccgcgg ctgggacgac ggcctctacg acccggaccc cgactcggcc
    13981 ggcaagacat acgcccgaga gggcggattc ctttacgacg cgggcgagtt cgacgcggac
    14041 ttcttcggga tctcgccgcg tgaggcgctg gcgatggacc cgcagcagcg gctgctcctg
    14101 gagacgtcct gggaggtgtt cgagcggtcg ggcatggacc cgacgacgct caggggcagc
    14161 tcgacgggcg tgttcaccgg cgtgatgcat cacgactacg gcgccgactc cgaaaccccc
    14221 gcgggcctgg agggctacgc ggtcaccagc acccagggca gcgtcgcctc cggtcgcatc
    14281 gcctacacct tcggcctgga ggggcccgcg gtgacggtgg acacggcgtg ctcgtcctcg
    14341 ctggtcgccc tgcatctggc cgtgcaggca ctgcgttcgg gcgaatgctc gctggcgctc
    14401 gcgggcggtg tgacggtgat ggcgacgcca tgggtgttcg tggagttcag caggcagcgc
    14461 ggcatggcgc ccgacggccg ctgcaaggcc ttctcggcgg cggcggacgg cgcgggctgg
    14521 tccgagggcg tgggcgtgct gctggtggag cgcctctcgg acgcccgccg caacggtcac
    14581 caggtgctcg ccgtcgtacg cggaagcgcc gtcaaccagg acggcgccag caacggcctc
    14641 accgccccca acggccctgc gcagcagcgg gtgatccgtg cggcgctggc cggtgccgga
    14701 ttgtcgtccg ccgacgtcga cgtggtcgag gcgcacggca cgggcaccac gctcggcgat
    14761 ccgatcgagg cacaggcggt cctcgccacc tacggccagg accgccccgc cgaccggccg
    14821 ctgcggctcg gatcgatcaa gtcgaacatc gggcacgcgc aggcggcggc gggtgtggcg
    14881 ggcgtcatca agatggtgca ggccgtgcgg cacggcgtgc tgccgcggac cctgcacgcc
    14941 gacgagccgt ccccgcacgt ggactggagc gccggcgcgg tcgaactgct caccgagaga
    15001 gccgactggg ccaccgacgg acgcccgcgc cgggccggtg tctcctcctt cggaatcagc
    15061 ggcacgaacg cgcacgtgat catcgaagag gctccggaag aaccgcggtc cgagcaggag
    15121 caggaaccgg cagggacgac cacggacgcg accggggaca cgtcggccgc ccttctgcct
    15181 tggcccgtct ccggtcggac cgaggcagcc ctgcgcgccc aggccgagcg gctcgcagca
    15241 tgggcgggcg ccgaaaccgg cctgcgcctg ccggacgtgg gtcactccct ggccacgacg
    15301 cgggcacacc tcgaacaccg cggtgtcgtg ctggcatcga accgcacgaa gaccctggcc
    15361 ggcctgaccg cgctggccga cgggctgcct gccgaaggcg tggtcaccgg gacggctccc
    15421 gaggagccgg gccgggtcgc cttcgtcttc cccggccagg gctcgcagtg gcagggcatg
    15481 gcggccgaac tcctcgagac ctcgccggtg ttcgcggccc ggctcgctga gtgcgacgcg
    15541 gcgcttcggc cgtacacggg ctggtccgtc accgacgcgg tccgtggcgg gcagggcgcg
    15601 ccgccgctgg acgacgtggt ggtcgtgcag tccgcgctgt gggcggtcat ggtgtcgctc
    15661 gcggcccagt ggcagtcgct gggcgtgcgc cccgacgcgg tcatcgggca cagccagggc
    15721 gagatcgccg ccgcggcggt ctccggcgcg ctgtcgctcg acgacgcggc gaaggtcgtg
    15781 tcgctgcggg cgcaggccat cgcccggaat ctgtcgggcc ggggcggcat ggtgtccgtg
    15841 ccgctccgcg ccgacgacgt ccgtgagcgc ctggcccgct ggggggagcg gatttccgtc
    15901 gcctcggtca acggcccgcg ctccacggtc gtctccggcg agccggaggc cctggacgaa
    15961 ctgctggccg cctgtgaggc cgacgaggtc cccgccaggc ggatccctgt ggactacgcc
    16021 tcccactccg cgcaggtgga agccatccgc gaggaggtcc tggcggccct cgccgacatc
    16081 gagccgcgtt gcggcgagat cccgttctac tcgacggtga ccggcggcct gttcgacacc
    16141 tcgggtgcgg acgccgagta ctggtacacg aacctgaggc aggaggtcag gttcgacgag
    16201 accgtgcgcg cgctgctcac cgacggcttc ggcttcttcg tcgagtcgag tgcccgcccc
    16261 gtgctgacca tcggactgga ggagaccttc gaggacaccg gctcccgcgc cgtcgccctc
    16321 ggcaccctgc gccgcgacga gggcggctgg gaaaggttcc tgacatccct ggcagagggg
    16381 tacgtgcacg gcctgcccgt cgactgggac gcggtgttcg ccggtgcgga cgcccaccgt
    16441 gccgatctgc ccacgtacgc gttccagcgg gagcggttct ggctggacgt cccggcccgg
    16501 cgcggtgacg tggcgggcct cggtctggcc gaggccgggc atccgctgct gggcgcggtg
    16561 gtgtccctgc cggacgaccg gggtgccctg tggaccgggc ggttgtccct ggcggagcag
    16621 ccgtggctcg ccgaccacgc ggtcttcggt tcagtggtgc tgcccggcgc ggtgctggtc
    16681 gaactggccc tccaggccgg tgggcgcgtg gcctgcggcc gcctggagga gctgacgctg
    16741 cagcagccgc tggtgctggg cgacgccggc ggtgtgcggc tgcaggtggc cgtgacaggg
    16801 gcggacgagg cggggcggcg tgccgtgacc gtgcactcgt gccctgacgg cggtggtgcg
    16861 gacgaggccg tgcccggcgg cgagacatgg acgctccacg ccacgggaac ccttgtcgac
    16921 ggcggcggcc cgttcgccgc ggccgacttg gcggcatggc cgccgcgcgg cgccgagaag
    16981 gtcgacgtga gcgatctgta cgaccggctg gcggatcagg gctacgggta cggcccggcg
    17041 ttccagggcg tgcggaccgc ctggcggcgc ggtgccgaga catacgccga ggtggcgctg
    17101 cccggcgtgg tgagcgggca ggccgcggga tacggcgtgc acccggcgct gctggacgcc
    17161 gtcttccaca tgtcgatcga cctgggtgcc gaggaggtac ggctgccttt catgtggtcc
    17221 ggcgtcgagg tctccggggc gagcacgtcg ccggtggtac gcgtggcctt ccatccggcg
    17281 gcagacggcg agctgtccct gcgggtggtg gacgaggcgg gtacgccggt gctctcggtg
    17341 gaccggctgg tcacgcgacc ggtggcgcgg gagcaactgc gcggcgcggg aggcgccttg
    17401 cgggaggcgc tgttcggcat ggagtgggca ccggggccga gcggctcgcg gacctcgacg
    17461 gagtggagcg agtgggacgc ccttgacgag gcagaggctg cgcccgggac ggtgctgtgg
    17521 ccgcacggtg gtgcggcggg tgagtccgtg tcggcagcaa cggcccgtgc gctcggtatc
    17581 gttcaggagt tcctgtcggc cgagcggttc gcgggctcgc gcctggtcat cctgacgcgc
    17641 ggcgccgtgg gcacgtccgc cgacgagcgc gtcaccgctc tgacggcggc tccggtctgg
    17701 ggcctggtgc gttcggcgca ggtcgaacac ccggaccggc tggtcctggt ggatgtggag
    17761 ccgggcctct ccccggccgc ggaggaagcc gctctgcgca ccgcgctgcg gggggcggag
    17821 ccgcaggtcg cggtccgcgg cggcaaggcc ctggtaccgc gtctgtcccg gatcgaggcg
    17881 ggcaggcagg acacggcccg gccgcggttc gatccgaagg gaaccgtgct cgtgaccggc
    17941 ggtacgggtg gtctgggcgc cctggtggcc aggcacctcg tgtcggcgta cggggtacgg
    18001 gacctgctgc tggtctcgcg ccgtggcaag gccgccgacg gcgtggacgc actggtcgcc
    18061 gaactcaacc ggtcgggcgc gcgcgtccgc gtcgaggcgt gcgacgtgag cgaccgtgcc
    18121 gcgctcgcca cgctgcttgc ctccgttccg caggaccgcc cgctcacggg tgtcgtccac
    18181 tccgccgccg tgctcgacga cggcgtgatc gaggcgctcg acgcggagcg gctggcgggc
    18241 gtgttccggc ccaagaccga tgcggcgctt cacctgcacg agctgacagc gggcctcggc
    18301 ctcagcgcgt tcgtgctgtt ctcgtccttc gccggagtgg tcggcagcgc gggccaggcc
    18361 ggctatgcgg cggccaacgt cttcctggac gccctcgcac acgagcggcg tgcacagggg
    18421 ctgcctgccg tctcgctggc ctggggctgg tggggttccg acggaggcct caccggaggc
    18481 ctgtcggacg tggaccgggg tcggctctcc gcactcggtc tggccgagat gtccggcgag
    18541 gaggggctcg ccctcctcga tgcgggcctg gcggccgacc gtgccgtggt ggttccggca
    18601 ctgctcgatg tggcagggct gcggaggcgc ggcgtcgagg acgtccccgt cgtgctgcgg
    18661 tcgctcgtgc gcggcgggcc acggcacgcc caggaccgga tcgcggaagc gggcaccgtg
    18721 gaggggcttg cggcacgcgt ggccggcctg agcgaggccg agcgggagcg ggtcgtcctg
    18781 gatctcgtac gtggtcatgt gagcggagtg ctcggctacg ggccgggccg gctcgtcgac
    18841 ctggagacgc cgttcaaggc tctcggcttc gactccctga tggcggtcga actgcgcaac
    18901 cgcctcaacc gtgccaccgg gctgcgcctg ccggcctccc tcgtcttcga ccacccgacc
    18961 gtccaggaac tgacccggta cgtcgtgacc aggctggagc aggaatcggg gccgggtacg
    19021 ggcgccgggg cggagccgat cctcgcggac ctcgggaagg tcgagcaggc gctgaccggg
    19081 acggacctcg gcggcgacgc gcgacagcgc atcgcggagc gcctgatgga tctgctgacc
    19141 ctctcgggac ccgagggcga cccggtcggg cccctcacgc aggcggaccc gggcacggac
    19201 ggcgaggacg gcggcggcac ggccttcgtc gaccagctgg aagcggcgac cccggacgag
    19261 atcctcgacg tcatcgaaaa agagttcgga aatctctgat cggctcccca cccccggccc
    19321 atctgaacgc acgtagcgga gtgaccccac atgactgaca acaagaacct gctgggcacg
    19381 ttgaagcggg ttgctcggga gctgcacgag acgcgccggc aactccagga ctcggagcgg
    19441 cgccggagcg agcccgttgc gatcgtgggc atggcctgtc gctaccccgg gggcgtcggc
    19501 tcgccggagg acctgtggca gctggtcgca catgccggcg aagccgtgtc ggacttcccc
    19561 gatgaccgtg gctgggacac cgacgccctc ttcgaccccg accccgaccg gccgggccgg
    19621 agcgccaccc gcaagggggg gttcctgtac gacgcggcgg agttcgatgc gggtttcttc
    19681 gggatctcgc cgcgtgaggc gctggcgatg gacccgcagc agcggctgtt gctggaggtg
    19741 tcctgggagg cgatcgagcg gtcgggcatg gacccgaagt ctctgaaggg cagccgcacg
    19801 ggagtctacg cgggcgtgat gtaccacgac tacgcggcgg gtctgccgac cgtccccgac
    19861 gagatcgagg gctactacgg tacggggacg gccgccagtg tcgtctccgg ccgcgtgccc
    19921 ttcaccctcg gcctgacggg cccggccatc acggtcgaca ccgcgtgctc gtcgtcgctc
    19981 gtcgcgctgc acctggccgt gcaggcgctt cgccgcgacg agtgctccct ggcgctcgcc
    20041 ggcggtgtgt cggtcatgtc gagcccggtc atgttcgccg agttcagtcg gcagggtggt
    20101 ctgtcggcgg atggccggtg caaggcgttc ggtgcggggg cggacggtac gggctggtcc
    20161 gagggtgtgg gtgtgctggt cctggagcgt ctgtcggacg cgcggcgcaa cggtcaccag
    20221 gtgcttgcgg tggtgcgtgg cagtgcggtg aatcaggacg gtgcgagcaa cgggttgacg
    20281 gctcccagtg gtccggcgca ggagcgggtc atccgcgagg ccttggccga cgcggacatg
    20341 tcggcggaga cggtcgatgc ggtggaggcg cacgggacgg gtacgaggct gggtgatccg
    20401 atcgaggcgc aggcgttgct ggcgacgtac gggcaggggc ggggggagga acagccgctg
    20461 tggctgggct cgttgaagtc caatctcggc cacgcgcaag ccgcggcggg tgtgggtggc
    20521 gtcatcaaga tggtgatggc gatgcgccat ggtgtgttgc cgcggacgtt gcatgtgggg
    20581 gagccgacgc cgctggtgga ctgggatgcg ggtgctgtcg agctgctggg tgaggccagg
    20641 gagtggccgg aggtggaggg gcgtccgcgg cgggcgggtg tgtcgtcgtt cgg
//
