LOCUS       NZ_BMWB01000042        16947 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces xantholiticus strain JCM 4863 sequence42, whole genome
            shotgun sequence.
ACCESSION   NZ_BMWB01000042
VERSION     NZ_BMWB01000042.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces xantholiticus
  ORGANISM  Streptomyces xantholiticus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 45219)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 114X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014651015.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:24:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,091
            CDSs (total)                      :: 7,016
            Genes (coding)                    :: 6,693
            CDSs (with protein)               :: 6,693
            Genes (RNA)                       :: 75
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 323
            CDSs (without protein)            :: 323
            Pseudo Genes (ambiguous residues) :: 0 of 323
            Pseudo Genes (frameshifted)       :: 187 of 323
            Pseudo Genes (incomplete)         :: 270 of 323
            Pseudo Genes (internal stop)      :: 13 of 323
            Pseudo Genes (multiple problems)  :: 140 of 323
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:39:19
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 16947
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMWB01000042.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..16947
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..16947
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..16947
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[5915:6947](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5916..6947)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(124..883)
                     /locus_tag="IE198_RS33545"
                     /pseudo=""
     CDS             complement(124..883)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030136.1"
                     /locus_tag="IE198_RS33545"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="trans-aconitate 2-methyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLRGYYGQEDSVSRTDTGTGAVTGAGADWTAWQQSWDRQQEWYMP
                     DREERFRVMLDMLEATVGPEPRVLDLACGTGSITARLLQRFPKATSTGVDLDPALLTIA
                     RGCFAGNERVTFVTADLKAPAWTAALPHTSYDAVHRRTGARRRRLHERRPHEGRVHTPH
                     QRGGTRAPPRRHGACQDGRRSRLDRLVGARRQGPGPRGTDRRAVPHLRRARRRRHPLRP
                     PARRDPAHGRLRRGPPGVGVAVGRTGARVEV"
     gene            930..1559
                     /locus_tag="IE198_RS33550"
                     /old_locus_tag="GCM10010381_68370"
     CDS             930..1559
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326935.1"
                     /locus_tag="IE198_RS33550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_68370"
                     /product="ABATE domain-containing protein"
                     /protein_id="WP_189893596.1"
                     /transl_table=11
                     /translation="MELAYYSDYAVRLVNTEEPARNKDSLTSVEAVRELFGESAQAARR
                     VSDSDVTRFRSVRGRLRAVFAAADAGEETQAVDLLNSLLLEFPVNPQISGHDYRDEDGR
                     PKWHMHLADHPSNATAGYAAIAAMGLAFHLTQYGVDRLGLCEATPCRNAYLDTSTNRSR
                     RYCSDRCATRANVAAYRARKRLETERSASTGRTAEASQETTPSTDR"
     gene            complement(1463..1903)
                     /gene="sodX"
                     /locus_tag="IE198_RS33555"
                     /old_locus_tag="GCM10010381_68380"
     CDS             complement(1463..1903)
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016485 - protein processing [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016437945.1"
                     /locus_tag="IE198_RS33555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_68380"
                     /product="nickel-type superoxide dismutase maturation
                     protease"
                     /protein_id="WP_373300054.1"
                     /transl_table=11
                     /translation="MGSRRWLMTEWWHEPRARFGFAEVTGPSMVPTLVHGDQLLVDYRA
                     TFRTGDVAVLRHPLQQDLLIVKRLAERRGEGWWVLGDNPGADGDSRVFGVVPPELLLGR
                     VRSRFRPLGEDQRSVLGVVSWLASAVRPVLADRSVSRRLRAR"
     gene            2034..2429
                     /gene="sodN"
                     /locus_tag="IE198_RS33560"
                     /old_locus_tag="GCM10010381_68390"
     CDS             2034..2429
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016151 - nickel cation binding [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313646.1"
                     /locus_tag="IE198_RS33560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_68390"
                     /product="superoxide dismutase, Ni"
                     /protein_id="WP_189893600.1"
                     /transl_table=11
                     /translation="MLSRLFAPKVKVSAHCDLPCGVYDPAQARIEAESVKAVQEKYQAN
                     EDPHFRARATVIKEQRAELAKHHVSVLWSDYFKPPHFEKYPELHQLINDTLKALSAAKA
                     STDPATGQKALDYIAQIDKIFWETKKA"
     gene            2619..4094
                     /locus_tag="IE198_RS33565"
                     /old_locus_tag="GCM10010381_68400"
     CDS             2619..4094
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014059941.1"
                     /locus_tag="IE198_RS33565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_68400"
                     /product="glycosyltransferase family 39 protein"
                     /protein_id="WP_229834792.1"
                     /transl_table=11
                     /translation="MAERLSNGAAGRPLSFVAPASLALALGLWGITRQSTMWRDESVTY
                     QVAHRTPSEIWALLDNADAVHGLYYFLMHALYSLWEGGLVTLRLPSVLAVAAAAGLVGL
                     TASRIAGHRAGVLSGLVFALTPEVQMYAQEGRSYAMVCTLVALATWLLARALTGPSAPR
                     SWALYSLAVLAASWLHEFAVLTLMAHGVTVLLARTTLRVRRCWAVAAGVAVIGLAPLVL
                     FSVGQAGQVSWIGGPKPREWLEITGVALVAVVCARYPAATGAGPVLVVRLALPLALLPT
                     AVLLLAAVHEPMYVDRYVLFTNVGFALLVGTSLSRLYTWASTLAPLRPRSARFAAVGAS
                     ATAVVLALTPVTLQMRTPDSRKDDVTAIAQEVQRVSAPGDGVLFTPSRRREWRLSYPAE
                     FGGLLDLALERSPKASASLQGEELPAAEIRSRMLALDRIVVLSDPPDQPQDAVEQEAVK
                     REVLRTRFHECSRTQLKGAQVTVYARSKRCTAE"
     gene            4146..4307
                     /locus_tag="IE198_RS33570"
     CDS             4146..4307
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE198_RS33570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_189893604.1"
                     /transl_table=11
                     /translation="MPRIWPVWGSSHCRYPVARSAASRYAAIRMRRERARVNRLRADEL
                     AAAVAKVS"
     gene            complement(4388..4831)
                     /locus_tag="IE198_RS33575"
                     /old_locus_tag="GCM10010381_68420"
     CDS             complement(4388..4831)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005312065.1"
                     /locus_tag="IE198_RS33575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_68420"
                     /product="DUF6304 family protein"
                     /protein_id="WP_189893607.1"
                     /transl_table=11
                     /translation="MSSESTEAWAGWYRDRQGAESVTISASGGQLRTCIRGVEYEGETF
                     AALRAAGGSPVLASCVLEWDMPLPVHADGAVQQATLSCLLTLGEPSRSGPLLDRADLNL
                     TLHYGGTAYEAGVADGDFDNALGRISRQLPPGAGLGQREPAQA"
     gene            complement(4902..5165)
                     /locus_tag="IE198_RS33580"
                     /old_locus_tag="GCM10010381_68430"
     CDS             complement(4902..5165)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013000783.1"
                     /locus_tag="IE198_RS33580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_68430"
                     /product="hypothetical protein"
                     /protein_id="WP_189893713.1"
                     /transl_table=11
                     /translation="MASNGPESSRTSHDPQHPYKCPGCGHPVAAIVKRHKTLGAYVPLW
                     APGPCRNPDCPLHVSADHVPAEAAAESPEDPDDTSGREVGTS"
     gene            complement(5221..5796)
                     /locus_tag="IE198_RS33585"
                     /old_locus_tag="GCM10010381_68440"
     CDS             complement(5221..5796)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973718.1"
                     /locus_tag="IE198_RS33585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_68440"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_189893609.1"
                     /transl_table=11
                     /translation="MRKLSYFIAASIDGFIGAPDGEADFFSKLVTGDFLEYLRDECPDT
                     LPTAARRAFGVEDVQNSRYDTVIQGRASYDLALKAGITSPYAHLREYVVSTSLKESPDA
                     NVRIVSGDVVAAVQELKKQDGLDIYLCGGANLAGQLIGEVDELVIKTYPAVLGSGMPMF
                     AAPFQVSDFSLESVRSFDNGVVVQQYSR"
     gene            complement(5916..6947)
                     /locus_tag="IE198_RS33590"
                     /old_locus_tag="GCM10010381_68450"
     CDS             complement(5916..6947)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889341.1"
                     /locus_tag="IE198_RS33590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_68450"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_189893679.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.1e-63, bitscore:
                     205.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDTVEGRDASDLLERTRSAVDPELRSAVASLPGSLRRVAMYHFG
                     WERADGIPAPRSAGKAVRPALVLAACRALGGDPFQAVRAAAAVELVHNFTLLHDDVIDE
                     DPTRRHRPTAWNVFGVPDAIIAGDAMSALALGLLAKDRHAAAAAASVRLTACVIELCAG
                     QQADCAFEERPPGEVTLDECIAMATAKTGALLGCACALGALYAGAGEEEVAAMDAFGRE
                     AGLAFQLVDDLIGIWGDPEQTGKPAGADLAAHKKSLPVVAALSSGTPAGAELAELYRGP
                     MSASAVRRATDAVERAGGRDWAQLHAADRMSRAVGELARAVPDLTPAGDLLALAEFVTR
                     RIR"
     gene            complement(7047..8465)
                     /locus_tag="IE198_RS33595"
                     /old_locus_tag="GCM10010381_68460"
     CDS             complement(7047..8465)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005312072.1"
                     /locus_tag="IE198_RS33595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_68460"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_189893611.1"
                     /transl_table=11
                     /translation="MTVGSVGSVGEDVRDPSPQQSLGTAAARNLATTTKSVPQMQEITS
                     RWLLRMLPWVQVQGGTYRVNRRLSYSVGDGRVTFVQTADRVAVIPAELGELPALRNFGD
                     EAALAELAQRCEQQEFAPGQVLAAGGEAADRIFLLAHGRVEKIGEGPYGDEAVVEVLAD
                     GAYFGDQSLVDGDAVWQYTARAATACTVLVLTRADVLNLAERAEPLRTHLANLASLPRQ
                     RTNKYGEAAIDLSAGHVGEAVVPHTFVDYEAAPREYELSVAQTVLKVHSRVADLYNQPM
                     NQTEQQLRLTVEALRERQEHELVNNREFGLLNNCDYGQRLQPHDGVPSPDDMDELLSRR
                     RGSKLFLAHPRAIAAFGRECNRRGLVPDSVDVAGHHVPAWRGVPIFPCNKIPISEARTT
                     SIICMRTGEEEQGVIGLQQSGIPDEIEPSLSVRFMGIDEQAIISYLVTAYYSAAVLVPD
                     ALGVLENVEVSRWR"
     gene            8614..9543
                     /locus_tag="IE198_RS33600"
                     /old_locus_tag="GCM10010381_68470"
     CDS             8614..9543
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005312075.1"
                     /locus_tag="IE198_RS33600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_68470"
                     /product="1-aminocyclopropane-1-carboxylate
                     deaminase/D-cysteine desulfhydrase"
                     /protein_id="WP_189893614.1"
                     /sec_met_domain="PALP (E-value: 1.5e-20, bitscore: 65.3,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPRPSEPAAALRPLLPSPLQPLEDDRFSRYGVRLLLKRDDLIHP
                     DLPGNKWRKLAPNLRAAAGRPVLTFGGAYSNHLRATAAAGRLLGFRTIGVVRGDELATR
                     PLNPSLARCAADGMRLLFVDRTTYRAKNDPEVLSRILEQAATDDVYVVPEGGSNALAAT
                     GCAELGRELRGLTDVAAVACGTGGTLAGLAAGLDDGQCAVGFPVLRGGFLAGAVRTLQD
                     EAFGGPVGDWSLDGRFHFGGYARTTPELDRFAADFRARHGLPVEGVYVAKLLYGLVELT
                     AEGSFAPGTTVAAVVTGHEDGSHPAGAD"
     gene            complement(9548..11146)
                     /locus_tag="IE198_RS33605"
                     /old_locus_tag="GCM10010381_68480"
     CDS             complement(9548..11146)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036096.1"
                     /locus_tag="IE198_RS33605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_68480"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_189893616.1"
                     /transl_table=11
                     /translation="MEVLSLVGLIAVSAAVAGAARRTPVPAPLLLVTAGLIASYVPGVP
                     DYHLDPHIVLPLVLPPLLHIAALDSSYLDLRANLRPIALLSVGYVLFATVVVGYLAYLL
                     VPDLPLPAALVLGAVIAPPDAVAATAIARRLGLPSRITTILQGESLVNDATAITAFKVA
                     LAAALGVGASWGGGLGEFAVASLGGVGVGLALMLPIHWLRRHLKEALLQNTLSLLIPFI
                     AYAAAEQVHASGVLAVVVVALYLGHHSWQVDFATRLQEDAVWRMVAFVLESAVFALIGL
                     QLAIVVEELGEYGVGEALWYAAGVFVAVVVVRFVWVYPATFLPRVLSRRIREREPDTNW
                     RAPLIVGWAGMRGVVSLAIAFSIPLTTSGGDDFPARNLVLFLTFTTVIGTLVVQGLTLP
                     SLIRVLKVPGRDVQAETLAEAQAQSKASAAAEQRLRELLEDERNRLPEPLADRLRAVLE
                     RRRNAVWERLGAVNAVTGESADDTYRRLATEMISTERAVFVELRNRREIDDEMMRTLLR
                     RLDLEEAAAYREETA"
     gene            11186..11446
                     /locus_tag="IE198_RS33610"
                     /old_locus_tag="GCM10010381_68490"
     CDS             11186..11446
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966374.1"
                     /locus_tag="IE198_RS33610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_68490"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_189893618.1"
                     /transl_table=11
                     /translation="MSECPHVAELPRPEPLPLTDTCAECAAAGSHPVQLRLCLSCGHVG
                     CCDSSPMRHASAHFQETAHSVMRSFEPGQVWRWCFVDGSIV"
     gene            11689..12102
                     /locus_tag="IE198_RS33615"
                     /old_locus_tag="GCM10010381_68500"
     CDS             11689..12102
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="IE198_RS33615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_68500"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_100111349.1"
                     /transl_table=11
                     /translation="MSQIAGEPGTQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGRAPERDTFAWTV
                     LSALAGKVDSSVADDRTVAISLYKQRGAGPGPA"
     gene            11991..13046
                     /locus_tag="IE198_RS33620"
                     /old_locus_tag="GCM10010381_68510"
     CDS             11991..13046
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005312082.1"
                     /locus_tag="IE198_RS33620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_68510"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_373300055.1"
                     /transl_table=11
                     /translation="MDGALRTGRQGRLVGRRRPYCGHQPVQTARRGTRAGVSSGNGDGS
                     MREDEERSPRPLSTSAGIPEQQARPHPVVDEPEGRTASAERADRMSEHRQNRHPDPHDR
                     SGARAMFIALRELPDGSPERAELRNQLVRMHLPLVEHLARRFRNRGEPLDDLTQVATIG
                     LIKSVDRFDPDRGVEFSTYATPTVVGEIKRHFRDKGWAVRVPRRLQELRLALTTATAEL
                     SQQHGRSPTVHELAERLGISEEEVLEGLESANAYSTLSLDVPDTDDESPAVADTLGAED
                     EALEGVEYRESLKPLLEDLPPREKRILLLRFFGNMTQSQIAQEVGISQMHVSRLLARTL
                     AQLRERLLVEE"
     gene            complement(13310..13726)
                     /locus_tag="IE198_RS33625"
                     /old_locus_tag="GCM10010381_68520"
     CDS             complement(13310..13726)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018892043.1"
                     /locus_tag="IE198_RS33625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_68520"
                     /product="hypothetical protein"
                     /protein_id="WP_189893620.1"
                     /transl_table=11
                     /translation="MSSDDRTSSPARPSRLSAAAAVCAAEGLALVMGGVYMLVMGLLGR
                     PDSPSQAEMGGLTLMALGVIPLAAARGLLRQRSWSRGPAIITQLIALIPAWTLLRASGA
                     LIPLGVVLAAVAVTGLVLLVNPTTAEALGIRPRA"
     gene            13808..14776
                     /locus_tag="IE198_RS33630"
                     /old_locus_tag="GCM10010381_68530"
     CDS             13808..14776
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127486.1"
                     /locus_tag="IE198_RS33630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_68530"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_189893622.1"
                     /transl_table=11
                     /translation="MRALLVVNPAATTTSARTRDVLIHALASEMKLEAVTTEYRGHARD
                     LGRRAAESDDIDLVVALGGDGTVNEVVNGLLHNGPDPDRLPRLAVVPGGSTNVFARALG
                     LPNDAVEATGAILDALRDRTEQTVGLGLAAGAPGTDDEGVPPRWFTFCAGLGFDAGVVG
                     RVEQHREQGKRSTHSLYVRQALRQFLDDPHRRQGTITLERPGAEPVAGLVLSIVCNTSP
                     WTYLGNRPVYASPKASFDTALDVLGLSKLSTPAVARYATQLLASSPERGPHGKHALTLH
                     DQTDFTLHSKVPLPFQMDGDHLGLRTSVAFTGVRRALRVIV"
     misc_feature    complement(14803..14816)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.73"
                     /tool="antismash"
     misc_feature    complement(14866..14875)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     misc_feature    complement(15037..15052)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    15040..15051
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     gene            15096..15353
                     /locus_tag="IE198_RS33635"
                     /old_locus_tag="GCM10010381_68540"
     CDS             15096..15353
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563321.1"
                     /locus_tag="IE198_RS33635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_68540"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_003953983.1"
                     /transl_table=11
                     /translation="MDWRHNAVCREEDPELFFPIGNTGPALLQIEEAKAVCRRCPVMEQ
                     CLQWALESGQDSGVWGGLSEDERRAMKRRAARNRARNASA"
     misc_feature    complement(16388..16402)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     misc_feature    16455..16469
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.6"
                     /tool="antismash"
     misc_feature    complement(16796..16810)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
ORIGIN
        1 ccccgcgacg tcctgaccaa cccacagcac gaccgcacca aatccttcct gtccaaggtg
       61 ctgtagcacg acacgagtga gggggcggta cggaccaggt ccgtaccgcc ccctcgtgca
      121 tgcctacttc aacgcgagca ccagtgcgtc cgacggcgac gcccacaccg ggcgggcctc
      181 ggcgaagccg gccgtgcgca gggtctcggc gtgccggtgg gcggaggggg tgtcgccgtc
      241 ggcgtgctcg ccgtagatgc ggaaccgctc ggcggtcggt tccgcgagga ccgggtcctt
      301 ggcggcgagc gcccaccagt cggtccagtc gagagcgccg gccgtcctgg cacgctccat
      361 gccgtcgtgg cggtgcgcgc gttccgccgc gttgatgcgg ggtgtggact cgtccttcat
      421 gtggtcggcg ttcatgaaga cgccgccgtc gcgcaccagt gcggcgatgc accgcgtcgt
      481 acgaggtgtg cggcagagcc gccgtccagg ccggggcctt gaggtcggcg gtgacgaagg
      541 tgacacgctc gttgccggcg aagcagcccc gggcaatggt caacagcgcg gggtcgaggt
      601 ccaccccggt gctcgtcgcc ttcgggaacc gctggaggag ccgtgccgtg atacttcccg
      661 taccgcacgc gagatccagc accctcggct cggggccgac cgtggcctcg agcatgtcca
      721 gcatcaccct gaaccgctcc tcgcggtcgg gcatgtacca ctcctgctgc cggtcccagc
      781 tctgctgcca ggccgtccag tcggcacccg cacccgtaac agcaccggta cccgtgtctg
      841 tgcggctcac ggaatcctct tgcccgtaat accctcgaag cataagcagc cgttaccttc
      901 accctagaac gccgcggtaa ggactacaag tggaactggc ctattactcg gactacgccg
      961 tgcgcctggt caacaccgag gagccggctc gcaacaagga ctccctcacc tcggtcgagg
     1021 cggtccgcga gctcttcggc gagtcggccc aggccgcacg ccgcgtgagc gactccgacg
     1081 tcacccgttt ccggtccgta cggggccggc tgcgcgcggt tttcgccgcg gcggacgcgg
     1141 gcgaggagac gcaggccgtc gacctgctca actcgctcct gctggagttc cccgtcaacc
     1201 cgcagatctc cgggcacgac taccgggacg aggacggccg ccccaagtgg cacatgcacc
     1261 tggcggacca cccgtccaac gcgacggcgg gatacgccgc gatcgccgcg atgggactcg
     1321 ccttccacct cacgcagtac ggcgtcgacc gcctcggcct gtgcgaggcc accccctgcc
     1381 gcaacgccta cctcgacacg tccaccaacc gctcacgccg ctactgctcc gaccgctgcg
     1441 ccacccgcgc caatgtggcc gcctaccggg cgcgcaaacg cctggagacc gagcggtcgg
     1501 cgagcacggg ccgcacggcc gaagccagcc aggagacgac gccgagcacg gaccgctgat
     1561 cctcgccgag cggacggaac cggctgcgta cccgcccgag cagcagttcg ggcggcacca
     1621 caccgaacac ccggctgtcg ccgtccgcgc cgggattgtc tccgagcacc caccagccct
     1681 caccgcgccg ctcggccagc cgtttgacga tgaggagatc ctgctgcagc gggtggcgca
     1741 gcaccgccac gtcgccggtg cggaacgtgg cccggtagtc gaccagcaac tggtccccgt
     1801 gcaccagcgt cggcaccatc gagggccctg tcacttcggc gaacccgaat cgcgccctcg
     1861 gctcgtgcca ccactcagtc atcagccacc tccggctccc cactgtatgt tcggccaccg
     1921 gcccgacccg cacgccggac ttttgaccta agcccaaggg ggcacccgcc gaaacgggtc
     1981 cctcacggag taatgtccca cctgagaaga cgatcacgag gaaggacagc tcaatgctct
     2041 cccgcctgtt tgcccccaag gtgaaggtca gcgcccactg cgacctgcct tgcggtgtgt
     2101 acgacccggc ccaggcccgc atcgaggcgg agtcggtcaa ggccgtccag gagaagtacc
     2161 aggccaacga ggacccgcac ttccgcgccc gcgccacggt catcaaggag cagcgcgcgg
     2221 agctcgccaa gcaccacgtc tcggtgctgt ggagcgacta cttcaagccc ccgcacttcg
     2281 agaagtaccc ggagctgcac cagctcatca acgacacgct caaggcactc tcggccgcca
     2341 aggcctcgac ggacccggcg accggccaga aggccctgga ctacatcgcc cagatcgaca
     2401 agatcttctg ggagaccaag aaggcctgac ctcgcgtcgg cttcccgcac ccggcccgca
     2461 ggactcctcg agtccgcagg ccgggtgcgg ccgtatgagg cagcaactgg acgcacatgc
     2521 tccggttgtg gcctggtggt gttggaggag gagccatcga gcttcgggaa caggccccgg
     2581 tcgcggaccg cccgcccgac gcccgggcgc cccttccggt ggccgagcgg ctgtcgaacg
     2641 gtgcggccgg ccgtccgctc tccttcgtcg ccccggcctc cctcgccctg gccctcgggc
     2701 tgtggggcat cacccggcag agcacgatgt ggcgcgacga gtccgtcacc taccaggtcg
     2761 cgcaccgcac cccctccgag atatgggcgc tgctggacaa cgccgatgcc gtgcacggcc
     2821 tctactactt cctcatgcac gccctctact ccctttggga gggcgggctc gtcaccctcc
     2881 ggctgccgtc cgtactggcc gtggccgctg ccgccgggct ggtcggcctc acggcgtccc
     2941 ggatcgccgg acaccgcgcg ggagtgttga gcggtctggt gttcgcgctc acgccggaag
     3001 tgcagatgta cgcgcaggaa gggcgctcct acgcgatggt ctgcaccctg gtcgcgctcg
     3061 ccacctggct gctggcccgc gcgctgaccg gaccgtccgc accgcgcagc tgggccctct
     3121 actcgctcgc cgtccttgcc gcgagctggc tccacgagtt cgccgtcctc accctgatgg
     3181 cgcacggagt gaccgtgctg cttgcccgta cgaccctgcg ggtgcggcgc tgttgggcgg
     3241 tggcggccgg ggtcgcggtg atcgggctgg ccccgctggt cctgttcagc gtcgggcagg
     3301 ccggccaggt gtcctggatc ggcgggccca agccgaggga gtggctggag atcacgggcg
     3361 tcgcgctcgt cgccgtcgtg tgtgccaggt acccggccgc caccggtgcg ggaccggtgc
     3421 tcgtcgtccg gctggccctg ccgctggcgc tcctgcccac ggcggtgctc ctgctggccg
     3481 cggtccatga gccgatgtac gtggaccggt acgtcctctt caccaacgtc ggtttcgcac
     3541 tcctggtcgg cacctcgctg agccggctgt acacctgggc gtccaccctg gcgccgctgc
     3601 gcccccggtc cgcgcgcttc gcggcggtcg gggcgtcggc gaccgcggtt gtcctcgcgc
     3661 tgactccggt gacgctgcag atgcggacgc cggacagccg gaaggacgac gtgacggcca
     3721 tcgcccaaga ggtgcagcgg gtctccgccc cgggcgacgg ggtcctcttc actccctcac
     3781 gccggcgcga gtggaggctg tcgtaccccg ccgagttcgg cggactcctc gatctcgctc
     3841 tcgagaggag tccgaaggcg tcggcgtcgc ttcagggcga ggagctcccg gctgccgaga
     3901 tccgcagccg catgctggcc ctggaccgga tcgtggtgct gagcgacccg cctgaccagc
     3961 cgcaggacgc cgtggagcag gaggcggtca aacgcgaggt gctgcgcacc cgcttccacg
     4021 agtgctcgcg gacgcagctg aaaggggctc aggtcaccgt ctacgcccgc tcgaagcgct
     4081 gcacggcgga gtagggaggc cccgagcgcg cggcttgcgc gggtcacgcc gccggcagag
     4141 ggcggatgcc gcgtatctgg ccggtgtggg gcagcagcca ctgccggtac ccggtcgccc
     4201 gcagcgccgc ctcacggtat gcggccatcc gaatgcgcag agagcgcgcc cgggtgaacc
     4261 ggttgcgggc cgacgagctc gcggccgcgg tcgccaaggt ctcctgacgg gacccggtcc
     4321 gccaggcagg ggcgcgccgc agtgcaggtg gggcgcccct tcgcccccgg tgcctcctgg
     4381 gtcccgctca ggcctgtgcc ggctcccgct gcccgagtcc ggcgcccggc ggcagttggc
     4441 ggctgatacg gccgagcgcg ttgtcgaagt cgccgtccgc gacccccgcc tcgtacgcgg
     4501 taccgccgta gtgcagtgtc aggttgaggt ccgcccggtc gaggagcgga ccgctccggg
     4561 aaggttcgcc gagcgtcagc agacagctga gcgtggcctg ctggaccgcg ccgtccgcgt
     4621 ggacgggcag cggcatgtcc cactccagga cgcacgaggc caggacaggg gacccgcccg
     4681 ctgccctgag agcggcgaag gtctcccctt cgtactcgac cccccttata catgtgcgca
     4741 gttggccgcc gctcgccgat atggtgaccg attccgcgcc ctgccggtcg cggtaccagc
     4801 ccgcccaggc ttccgttgac tccgatgaca tgcgcggact gtagcggtag ggccgttcgg
     4861 gccgcgcccc aggtgccact cggttctttc gcggacgaac ctcaggatgt gccgacctcc
     4921 cggccggacg tgtcgtccgg gtcctccggg gactcggcgg cggcctccgc ggggacatga
     4981 tccgcggaga catggagagg gcagtccggg ttgcggcagg gtcccggtgc ccacagcggg
     5041 acgtacgcgc ccagcgtctt gtgccgcttc acgatggcag ccaccgggtg cccgcatccg
     5101 gggcacttgt acgggtgctg cgggtcatga ctggtccggg acgattcagg tccgttgctg
     5161 gccataagga aagaatatgc cggtcccctc gaccgtggca gtacggcccg cccgtcagtc
     5221 ctaccggctg tactgctgca cgaccacgcc gttgtcgaag gaccgcaccg actccagcga
     5281 gaagtcggag acctggaacg gcgccgcgaa catgggcatg cctgacccga gcacggccgg
     5341 gtaggtcttg atgacgagct cgtcgacctc accgatcagc tgccccgcga gattcgcgcc
     5401 gccgcagaga tagatgtcca gaccgtcctg cttcttgagc tcctggaccg cggcgaccac
     5461 atcaccggag acgatgcgca cattggcatc gggcgactcc ttgaggctgg tcgacaccac
     5521 atactcgcgc aggtgggcgt aggggctggt gatgcccgcc ttcagcgcca ggtcatagct
     5581 ggcgcgtccc tgtatgaccg tgtcgtaccg gctgttctgc acgtcctcga caccgaaggc
     5641 gcgacgggcc gcagtcggca gggtgtccgg gcactcgtcc ctgaggtact ccagaaagtc
     5701 tcctgtcacc agcttgctga agaagtccgc ctcaccgtcc ggggctccga tgaagccgtc
     5761 gatggaggct gcgatgaagt agctgagctt tcgcacgctg atcccctgat cgttggaagc
     5821 cgaaggggtc ggcgaaaagg gcgctgacca cttcatccat agtgcttcga ttgcagttct
     5881 caccgcaagc actttccgtg cgccgctcgt acggatcagc ggatgcggcg ggtgacgaac
     5941 tcggccagcg ccagcagatc cccggccggc gtcaggtccg ggaccgcacg tgccagttcg
     6001 ccgacggcgc gtgacatccg gtcggcggcg tgcagctggg cccagtcccg cccgcctgcc
     6061 cgttccaccg cgtccgtggc gcggcggacc gcggaggcgc tcatcggccc gcggtacagc
     6121 tcggccagct cggcaccggc cggagtgccc gaggacaggg cggccaccac cgggagggac
     6181 ttcttgtgcg cggcgagatc cgcgcctgcc ggcttgccgg tctgctccgg gtccccccag
     6241 atcccgatga gatcgtcgac gagctggaag gccagcccgg cctcccgccc gaaggcgtcc
     6301 atggccgcga cctcctcctc tcccgcgccc gcgtacagcg cgccgagcgc gcaggcgcag
     6361 cccagcaggg ccccggtctt ggccgtcgcc atggcgatgc actcgtccag ggtgacctcg
     6421 cccggtggtc gttcctcgaa ggcgcagtcg gcctgctgcc cggcgcacag ttcgatgacg
     6481 cacgccgtca gccgcaccga cgccgccgcc gcagccgcat gccggtcctt ggcgagcagt
     6541 ccgagcgcga gcgccgacat cgcgtccccg gcgatgatgg cgtcggggac accgaacacg
     6601 ttccacgccg tggggcggtg cctgcgggtg gggtcctcgt cgatcacgtc gtcgtgcagc
     6661 agggtgaagt tgtgcacgag ttccaccgcg gcggccgccc gcaccgcctg aaaggggtca
     6721 ccgccgagcg ctcggcaggc ggcgagcacc agcgccggcc ggacggcctt gcctgcggac
     6781 ctgggggccg ggatgccgtc ggcccgctcc cagccgaagt ggtacatggc gacccggcgc
     6841 agggagccgg gcagcgacgc gacagcggaa cggagttcgg ggtcgacggc actgcgggtg
     6901 cgctcgagga ggtcggaggc gtcacggcct tcgacggtgt ccggcatggt caactgggcg
     6961 gtcctttcct gtgatggctt cgctccccgc ggacggggac gcggcggggt cgccgcgccc
     7021 ccttgaggtc acgtcgtcga ggagcgtcac cgccaacggc tcacttccac gttctccagg
     7081 acgccgagcg cgtcggggac cagcaccgct gccgagtagt aggccgtgac caggtacgag
     7141 atgatcgcct gctcgtcgat gcccatgaag cgcaccgaaa gactgggctc gatctcgtcc
     7201 gggatgccgc tctgctgcag cccgatgacg ccctgctcct cctcgcccgt acgcatacag
     7261 atgatcgatg tcgtccgggc ctcggagatc gggatcttgt tgcacgggaa gatcggcaca
     7321 ccgcgccagg cgggcacatg gtgtcccgcg acgtccacgc tgtcgggcac caggccccgg
     7381 cggttgcact cgcgtccgaa ggcggcgatg gcgcgcgggt gggcgaggaa gagcttcgag
     7441 ccgcgccgcc gcgagagcag ttcgtccatg tcgtcggggc tcggcacacc gtcgtgcggc
     7501 tgcagccgct gcccgtagtc acagttgttg agcaggccga actcgcggtt gttgacgagc
     7561 tcgtgctcct gccgctcgcg cagcgcctcg acggtcagcc gcagctgctg ctccgtctgg
     7621 ttcatcggct ggttgtagag atccgccacc cggctgtgca ccttcagcac cgtttgggcg
     7681 acgctcagtt cgtactccct cggcgccgcc tcgtagtcca caaaggtgtg cggcacgacg
     7741 gcctcgccga cgtgcccggc cgacaggtcg atcgccgctt cgccgtactt gttcgtccgt
     7801 tggcggggca gcgaggccag gttcgccaga tgggtgcgca gcggctccgc ccgctccgcc
     7861 aggttgagca cgtcggccct ggtcaggacc aggaccgtgc aggcggtcgc ggcacgtgcc
     7921 gtgtactgcc agacggcgtc gccgtccacc agtgactggt cgccgaagta ggcaccgtcg
     7981 gcgaggactt cgaccaccgc ctcgtccccg tacgggccct cgccgatctt ctccaccctg
     8041 ccgtgcgcca gtaggaagat ccggtcggcc gcctccccgc cggccgccag cacctgcccc
     8101 ggcgcgaact cctgctgctc gcaccgctgc gccagctccg cgagcgccgc ctcgtcgccg
     8161 aagttccgca gcgccggcag ctccccgagc tcggccggga tcaccgcgac acggtccgcg
     8221 gtctgcacga acgtgacccg cccgtcgccg accgaatagc tgaggcggcg gttcacccgg
     8281 taggtgccgc cctgtacctg cacccacggc agcatccgca gcagccaccg tgaggtgatc
     8341 tcctgcatct gcgggacgga cttggtggtg gttgcgagat tccgtgcggc ggcggtgccg
     8401 agactctgct ggggcgacgg gtcgcgaacg tcctcgccca cggaaccgac cgaaccaacc
     8461 gtcatgagac tccctctcga tcatgtgctg acctgcaagg aaaagccttc catcgcatcc
     8521 tgtaagcggt ccattacaca aatgagtgtg actggatccc cacggagcag ggcagtagcc
     8581 ggatccgctc gcacatgcga ccagaatgag tgcatgccgc cgagaccgtc cgagcccgct
     8641 gccgcactgc ggcccctgct gccgtcaccg ctgcagccac tcgaggacga tcgtttctcc
     8701 cggtacgggg tgcggctgct cctcaagcgc gacgacctga tccacccgga tctgccgggc
     8761 aacaaatggc gcaagctggc cccgaacctg cgggccgcgg caggccggcc ggtgctgacg
     8821 ttcggcggcg cgtactccaa ccatctgcgc gcgacggccg cagcgggccg gctgctcggc
     8881 ttccgcacga tcggcgtcgt acggggcgac gagctcgcca cgcgccccct gaacccctcc
     8941 ctggcccggt gtgcggcgga cggcatgcgc ctgctgttcg tcgaccgcac gacgtaccgc
     9001 gccaagaacg accccgaggt gctgtcccgg atactcgaac aggcggcgac ggacgacgtc
     9061 tacgtggttc ccgaaggcgg cagcaacgcg ctcgccgcca cgggctgcgc cgaactcggc
     9121 cgcgagctgc gcggcctcac cgacgtggcg gccgtcgcct gcgggaccgg cggcacgctc
     9181 gccggactgg ccgccggact cgacgacggg cagtgtgccg tcggcttccc ggtcctgagg
     9241 ggcggattcc tcgccggtgc cgtgcgcacc ctccaggacg aggccttcgg gggccccgtc
     9301 ggcgactggt ccctggacgg gcggttccac ttcggcgggt acgcccgtac gaccccggag
     9361 ctcgaccggt tcgccgccga cttccgggct cgccatgggc tgcccgtgga gggcgtctat
     9421 gtcgccaagt tgctctacgg acttgtggag ctcacggccg aggggtcctt cgcccccggc
     9481 acgaccgtcg ccgcggtcgt caccggtcac gaggacggat cgcaccctgc cggcgccgac
     9541 tgacggctca ggccgtctcc tcgcggtatg cggccgcctc ctccaggtcg agccggcgca
     9601 gcagcgtacg catcatctcg tcgtcgatct cccgccggtt gcgcagctcg acgaagaccg
     9661 cgcgctccgt ggagatcatt tccgtggcga gccgccggta cgtgtcgtcc gccgactccc
     9721 ccgtcacggc gttgaccgcg ccgagccgtt cccagaccgc gttccttcgg cgttccagta
     9781 ccgcccgcag ccggtccgcc agcggctccg gcagcctgtt gcgttcgtcc tcaagcagct
     9841 cccgcagccg ctgttcggcc gccgcggagg ccttgctctg ggcctgcgcc tcggccagcg
     9901 tctccgcctg gacgtcgcgt cccgggacct tgagcacacg gatcagcgac ggcagggtca
     9961 gtccctgcac caccagcgtc ccgatcaccg tcgtgaaggt gaggaacagg accaggttgc
    10021 gggcggggaa gtcgtcgccg cccgacgtcg tcagcgggat cgagaaggcg atggcgagcg
    10081 ataccacccc gcgcataccg gcccagccga cgatcagcgg agccctccag ttggtgtccg
    10141 gctcgcgttc cctgatccgc cgggacagca cacgcggcag gaacgtcgcc gggtacaccc
    10201 agacgaaccg caccacgacc acggcgacga agaccccggc cgcgtaccag agcgcttcgc
    10261 ccacgccgta ctcgcccagc tcctcgacca cgatcgccag ctgcaggccg atgagcgcga
    10321 agacggccga ctccaggacg aaggcgacca tcctccagac ggcgtcctcc tgcagccggg
    10381 tcgcgaagtc gacctgccag gagtggtggc ccaggtacag cgcgacgacg acgaccgcga
    10441 gcacacccga cgcatggacc tgctccgcgg cggcgtaggc gatgaacggg atgagcagcg
    10501 acagcgtgtt ctgcagcagc gcttccttca gatgtctgcg cagccagtgg atgggaagca
    10561 tcagcgccag gccgaccccc acaccgccga gcgaggccac ggcgaactcc ccgaggccgc
    10621 cgccccagct cgcgccgacg ccgagggccg cggccagcgc caccttgaag gcggtgatcg
    10681 cggtggcgtc gttcaccaag gattcacctt ggaggatcgt ggtgatacgg gacggcagtc
    10741 ccagccggcg cgcgatggcc gtggcggcga cggcgtcggg cggtgcgatc acggcaccga
    10801 gcaccagggc ggccggcaac ggcagatccg gcaccagcag ataggccagg tagccgacga
    10861 cgaccgtcgc gaacaggaca tagccgaccg agagcagcgc gatgggacgg aggttggccc
    10921 gcaggtcgag gtaggaactg tccagggcgg cgatgtgcag cagcggtggc aggaccagcg
    10981 gcagcacgat gtgcgggtcg aggtggtagt cggggacgcc cgggacgtac gaggcgatca
    11041 gcccggccgt caccagcagc agcggcgccg gcaccggcgt cctgcgggcc gccccggcca
    11101 ctgcggcgct cacggcgatc agcccgacca gcgacaatac ttccatcaca ccgacctcac
    11161 tcgactgcgt cgtaatctgg caatcatgag cgagtgtccg cacgtagccg aactgccgcg
    11221 ccccgagcca ctgccgctga ccgacacctg cgcggagtgc gcggcggccg gcagccaccc
    11281 cgtccagctg cggctgtgcc tgtcgtgcgg gcacgtcggc tgctgcgact cgtcgccgat
    11341 gcgacacgcg agcgcccact tccaagagac cgcgcattcg gtgatgcgca gtttcgagcc
    11401 gggacaggtg tggcgatggt gtttcgtgga cggttcgatc gtctgacgcc tgggtacgtc
    11461 aaccatcccc cggatccgct caattggcag gcgcagaccc ctagccactg tgcgtgttca
    11521 tcgttttaca ttgagtgaca gccatcacca tgggggcgct ggcgacacgg caccatggat
    11581 cgcgatagcg tcgccaggcc agacatggct gcgtgaccga ccacgtaacg cacggccgcg
    11641 ggccaacgcc gcggcccgga atgagcttgt gccaccttgg aggtgagggt gtcccagatc
    11701 gcaggcgagc ccgggaccca ggacttcgtg gaagtccggc tgcccgctgc gggtgcctac
    11761 ctgtccgtgc tgcgaacggc caccgccggc ctcgcagcgc gtttggactt caccctcgac
    11821 gagatcgagg acctgcggat cgcggtggac gaggcgtgcg cgatcctgct gcagcaggcc
    11881 gtcccaggat ccgttctgag ctgcgtgttc cggctcgtcg acgactcact ggaggtgacg
    11941 gtctccgcac ccaccaccga cggccgggcg ccggagcgcg acacgttcgc ctggacggtg
    12001 ctctccgcac tggccggcaa ggtcgactcg tcggtcgccg acgaccgtac tgtggccatc
    12061 agcctgtaca aacagcgcgg cgcgggaccc gggccggcgt gagcagcgga aacggggacg
    12121 gttcgatgcg ggaggacgag gagcggagcc cgaggccgct gagcacgtcg gccggcatcc
    12181 ctgagcagca ggcgcggccg cacccggtgg tggacgaacc tgagggccgt acggcctcgg
    12241 cagagcgggc ggaccgtatg agcgaacacc ggcagaaccg gcacccggac ccccatgacc
    12301 gcagcggcgc acgggcgatg ttcatcgcac tgcgcgagct gcccgacggg tcgcccgagc
    12361 gggcggagct gcgcaaccag ctcgtccgga tgcatctgcc gctggtcgag cacctggcgc
    12421 ggcgcttccg caaccgcggc gaaccgctgg acgacctgac gcaggtcgcc acgatcgggc
    12481 tgatcaaatc ggtggaccgg ttcgatccgg accgcggcgt cgagttctcg acgtacgcca
    12541 caccgacggt ggtcggcgag atcaaacgcc acttccgtga caaggggtgg gcggtgcggg
    12601 tgccgcgccg tctgcaggag ctgcgactcg cgctcacgac cgcgaccgcg gagctctccc
    12661 agcagcacgg ccggtcaccg accgtgcacg agctggcgga gcggctcggc atctcggagg
    12721 aggaggtcct ggaaggcctg gagtccgcga acgcgtactc cacgctctcc ctcgacgtcc
    12781 ccgacacgga cgacgagtcc cccgcggtgg cggacacgct gggcgcggag gacgaggcac
    12841 tggagggcgt cgagtaccga gagtccctga agccgctgct ggaggatctg ccaccgcgcg
    12901 agaagcggat tctgctgctg cggttcttcg ggaacatgac ccagtcccag atcgcacagg
    12961 aggtcggcat ctcgcagatg cacgtctccc ggctcctggc gcggacactg gcacaactcc
    13021 gcgaacgcct gctggtcgag gagtagccct cggggcggcc cacctggatg aagccggtgg
    13081 gccggcgcgg ggtgcggaga agtccgtcac cccgcccctt cccgaaaccc cactcccgga
    13141 ccgctaccgc gctccgcccc ggacggctct tttggagccc gccggcgttc gaggcgcggg
    13201 ggcgcggggc cggagcccct gggttcgcaa tgagggcacc gcgcacgccg ccaggagtag
    13261 gaggagggcg gggcggggga aacgggccgc gcagccgccc gctcgagggc tacgcccgcg
    13321 ggcggatgcc gagggcctcg gccgttgtcg ggttcaccag cagcaccagg cccgtcaccg
    13381 cgaccgccgc cagcaccacg cccagcggga tcagcgcgcc cgaggcgcgc agcagggtcc
    13441 acgccgggat cagtgcgatc agctgagtga tgatcgccgg cccgcggctc cagctgcgct
    13501 gccgcagcag cccgcgcgcc gccgccagcg ggatgacgcc gagcgccatc agcgtcagac
    13561 cgcccatttc tgcctgggag ggactgtcgg gccggcccag cagccccatc acgagcatgt
    13621 acacgccacc catgaccagg gccagaccct cggcggcgca caccgcggcc gccgcggaca
    13681 aacgggaggg gcgggcgggg ctggaggtcc ggtcgtcgct gctcacccat gcagggtagc
    13741 cgtcacgccg gtccgcccgg gaaacccggg ctgggccaga taccccccag taggtacgct
    13801 gcatcgcatg cgcgcacttc tcgtggtcaa tccggcagca accaccacca gtgcccgcac
    13861 ccgcgacgta ctgatccacg cactcgcgag cgagatgaag ctcgaggcgg tcaccaccga
    13921 gtaccgcggc cacgcccgcg acctcgggcg ccgggccgcg gagtcggacg acatcgacct
    13981 cgtcgtcgcc ctcggcggtg acggcaccgt caacgaggtc gtcaacggac tcctccacaa
    14041 cggccccgat ccggaccgtc tcccccgcct cgccgtcgtc cccggcggct cgacgaacgt
    14101 gttcgcccgc gccctcggcc tgccgaacga cgccgtcgag gcgaccggcg cgatcctgga
    14161 cgcgctgcgc gaccggaccg agcagacggt gggcctcggc ctcgcggccg gcgctcccgg
    14221 caccgacgac gagggtgtcc cgccgcgctg gttcaccttc tgcgcagggc tgggcttcga
    14281 cgccggcgta gtcggccggg tcgaacagca ccgcgaacag ggcaagcggt cgacgcactc
    14341 gctctatgtc cggcaggcgt tgcggcagtt cctcgacgac ccgcatcgcc gccaaggcac
    14401 gatcacgctg gagcggccgg gcgcggagcc cgtggcgggt ctggtgctgt ccatagtctg
    14461 taacacctcc ccctggacct acctgggcaa tcgcccggtg tacgcgtccc ccaaggcctc
    14521 cttcgacacc gccctcgacg tgctcgggct gtcgaaactg tcgacccctg ccgtggcccg
    14581 ttacgcgacc cagttgctcg cttcgagccc ggagcgcggc ccccacggaa agcacgcgct
    14641 cacactccac gaccagaccg acttcacctt gcattcaaag gtgccgctgc ccttccagat
    14701 ggacggtgac cacctcgggc tgcgtaccag cgtggcgttc acaggcgtac gccgtgcact
    14761 gcgtgtgatt gtgtgaccag aaggaccgaa agtcctttat ctcgaacgta tgggctgcgg
    14821 tccaccccat agaagtacgg ctgtgaccta gtcgacaccg aggaatcaaa aaaaactttc
    14881 cggaaggggt tgtatccgcc gccgaggttt gcgaatctct acatggcgat cgggacggcc
    14941 cgcaacatcg gccccacaga ccgccggaac cccttacacg aatccaggac ccaacgccgg
    15001 gcaactggcg gtcggccctt ccctcacggg gggactcgtg aaagcgttca cattcacaag
    15061 caacccgaac gtaataccaa ggagaggtag cagccatgga ctggcgtcac aacgccgttt
    15121 gccgcgagga agaccccgag ctgttcttcc ccatcggcaa caccggtcct gcgctgctgc
    15181 agatcgagga agccaaggcc gtctgccgtc gctgccccgt catggagcag tgtctgcagt
    15241 gggcgctcga gtccggccag gactccggcg tctggggtgg cctcagcgag gacgagcgcc
    15301 gcgcgatgaa gcgccgtgcc gcccgcaacc gggcgcgtaa cgccagcgcc tgacgccccc
    15361 tgctaccggc ctccgccggc ggcgcgtaca gcgagtacgc actcaccgcc ttcgagccgc
    15421 agcgcgcagt acccccgatg cgcatcgcac atgcgagcac gtgagcttcg agccccggac
    15481 cgtttcacac ggtccggggc tcttcgctgt cccggcgtgg aaccggggcg ctcagcgctt
    15541 gtcgggcacg gggatgtcca gaacaacccg ggtgccgcgc cccggctcgg ggaccggaag
    15601 catgtcgaag gtcccgccca gttctccttc gacgagcgtc cgcacgatct gcagccccag
    15661 attcccggtc cgctgcgggt cgaagccctc cggcagaccg cggccgtcgt cctggacggt
    15721 gatcagcagc cgggagctct gggcgtgagc ctcgccgcgc accgcggcga cctccaccga
    15781 accgtgctcg cccggcgcga aggcgtgctc gagggcgttc tgcagcacct cggtgagcac
    15841 catggacagc ggcgtggcga cttcggcgtc caggatgccg aagcggcccg tgcgccggca
    15901 ggcgacttta cccggtgaga tctccgcgac catcgcgatc acccggtccg cgatgtcgtc
    15961 gaactccacc cgctcgtcga ggttctggga cagcgtctcg tgcacgatcg cgatggaacc
    16021 cacccgtcgc accgcctcgt tgagggcctc acggccgcgt gcggagtcca tccggcgcga
    16081 ctggaggcgc aacagcgcgg caaccgtctg gaggttgttc ttcacccggt ggtggatctc
    16141 ccggatggtc gcgtccttgg tgatcaactc gcgctcgcgg cggcgcagtt cggtcacgtc
    16201 ccgcagcagc accagcgatc cgatccgtac gcccttcggc ttgagcggga tcgcccgcag
    16261 ctggatgacg ccgccgttgc cctccacctc ggtctcgcgt ggcgcgtagc cgctggcgat
    16321 cttgaccagg gcctcgtcga cagggccgcg ggagggggcg agttcggcgg tgagctggcc
    16381 gagatgctgg ccgacgaggt cggaggcgag cccgaggcgg tggtacgcgg agaggccgtt
    16441 ggggctggcg tactggacga tgccgtccgc gtcgagccgg atgagcccgt caccggcacg
    16501 cggtgaggag tccatctcga cctgttcctc ggggaagggg aacgttccgg cagcgatcat
    16561 ctgcgccagg tcggaggcgg actggaggta ggtcagctcg agccgcgacg gggtgcgcac
    16621 ggtgagcaga ttggtgttgc gcgcgatgac gccgaggacg cggccctcac ggcgtacggg
    16681 gatggactcg acccgtaccg gcacctcctc gcgccactcg gggtcgccct cgcgcacgat
    16741 ccggccctcg tcgagcgcgg cgtccaggag aggacgccgg ccgcggggga cgaggtggcc
    16801 gaccatgtcg tcctggtacg aggtggggcc ggtgttgggc cgcatctggg cgacggagac
    16861 gtaccgggtg ccgtcgcggg tggggaccca cagcacgagg tcggcgaagg agaggtcgga
    16921 gagcagctgc cactccgaga ccagcag
//
