LOCUS       NZ_BMWB01000030        21017 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces xantholiticus strain JCM 4863 sequence30, whole genome
            shotgun sequence.
ACCESSION   NZ_BMWB01000030
VERSION     NZ_BMWB01000030.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces xantholiticus
  ORGANISM  Streptomyces xantholiticus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 82906)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 114X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014651015.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:24:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,091
            CDSs (total)                      :: 7,016
            Genes (coding)                    :: 6,693
            CDSs (with protein)               :: 6,693
            Genes (RNA)                       :: 75
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 323
            CDSs (without protein)            :: 323
            Pseudo Genes (ambiguous residues) :: 0 of 323
            Pseudo Genes (frameshifted)       :: 187 of 323
            Pseudo Genes (incomplete)         :: 270 of 323
            Pseudo Genes (internal stop)      :: 13 of 323
            Pseudo Genes (multiple problems)  :: 140 of 323
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:39:19
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 31439
            Orig. end                         :: 52456
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMWB01000030.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21017
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21017
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21017
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11017](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11017)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            87..710
                     /locus_tag="IE198_RS30505"
                     /old_locus_tag="GCM10010381_62000"
     CDS             87..710
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005310853.1"
                     /locus_tag="IE198_RS30505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_62000"
                     /product="hypothetical protein"
                     /protein_id="WP_189892462.1"
                     /transl_table=11
                     /translation="MPTPPTPKSGKPPGAGLPDGLPVPGRFSHLHPDDGACLMEEASLL
                     ATGRFTDRPPGTHPVLAALARAVNDAVDDATRHTLWPLAADLADANPADRAYGPLLVGT
                     VVDAALRVRPESRRLKWRSAACHARAHRLARARTATTPARIADMLWWRGPGHHHLEHAL
                     RVLLTAPDADQRLARLLHRAVSEARVRTTVEQAPTHAETSSQRG"
     gene            complement(988..3240)
                     /locus_tag="IE198_RS30510"
                     /old_locus_tag="GCM10010381_62010"
     CDS             complement(988..3240)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="IE198_RS30510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_62010"
                     /product="sensor histidine kinase"
                     /protein_id="WP_189892466.1"
                     /transl_table=11
                     /translation="MESALRRSFAGMALLFVVAWWIVVASLVVSGSVGLHPLTSAAAVL
                     FAGCTAAWAYRGAFVRIGRYDALTAVAVALAVHAAYALEQPDEIVTGLRCMVTVTAVLL
                     AVAYLPGVWGRPLAVVCLAAQVAAGWHEGMWTALEGIWPPFAGGVAAAVLAPVMRGAGE
                     RADAAVREDLDASEAAAREQAARRSQRDFQRLLHDDVGAALRAAGTRGVPVDEQRAEAR
                     RAVAGLTAGAAPEEDGAETDLVSLLSGLVATSVGGLPRPRVSTDFPSGGLPLPHEVAAA
                     CTGAAVEALRNVRYAGASHVHVRLSGDRRALELAVCDNGKGFSVSQVRKTAVGLQDSVR
                     QRMTDVGGEADVHSEPGRGTTVRLRWSSPVAAPGGGVPAGRRGRLETLRAAVGDVRAPL
                     AAVCLPYLAVMVVVAVVRTVHMPQMVAHLVWYAALTAATCILLGRAHRRISAKVAAVLL
                     VVATAGAVSSLLVIPPEGITDYRSWPIGAVTPLLTLLVVVRPLRQTALALACEEAGIVI
                     LVAADPPAAATPTGAVAMALPAMLAPAMGVVMGLVIRRTLVTLGGAVLDAHRHRMVVVA
                     TESAARARAVQHRRRLAEIDEQVLPFLRSVATGETHDPGALRGRADRLAQSIRDELHLP
                     GVFDRPLRELVGGARESGCVVTVHAHADLDVPPVDAAARTALVRSVLSAALRGQETPAE
                     MVLSIQDGARQPGLSLVVMPGDTRRADALRAALEPGTYTLEDTADLTWAEVSFRRS"
     gene            complement(3267..3959)
                     /locus_tag="IE198_RS30515"
                     /old_locus_tag="GCM10010381_62020"
     CDS             complement(3267..3959)
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.5"
                     /locus_tag="IE198_RS30515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_62020"
                     /product="response regulator transcription factor"
                     /protein_id="WP_189892468.1"
                     /transl_table=11
                     /translation="MNGTQGASSEDTAAGALLAAVDDHPVILHGIRACLTELAPEVTWV
                     GSAETVTDLPSRVTVVPTVVLLDIELSDGSDVGENVGRLREWGPHVMLFSREHRPVVVR
                     RGIEAGALGLVLKEDPDAQLVEAIGAAHSGKAYVSSRLAHQIVNDQRGKVRLSARQLEV
                     LELLARGLRPADIAKRLYMSEDTVKTHRRRAIDAFAKGGGKKLDYNSQLVWRSVLDGHI
                     DIGPDVAE"
     gene            4158..4541
                     /locus_tag="IE198_RS30520"
                     /old_locus_tag="GCM10010381_62030"
     CDS             4158..4541
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE198_RS30520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010381_62030"
                     /product="hypothetical protein"
                     /protein_id="WP_189892469.1"
                     /transl_table=11
                     /translation="MGRFTKRVGAFESPHSVADTMTILYNGVSEQLSNATPTVSEPGLA
                     ASIYLTRFDDSGLTVTAGNRIETYFRFMVDVTSNGSGCVGEAYFDRRMGAINRWMGNAM
                     GLTGGLSLTFQQCSIRTRGWTIA"
     misc_feature    4568..4581
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.67"
                     /tool="antismash"
     misc_feature    5058..5073
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     gene            5143..6333
                     /locus_tag="IE198_RS30525"
                     /old_locus_tag="GCM10010381_62040"
     CDS             5143..6333
                     /EC_number="1.6.5.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010047385.1"
                     /locus_tag="IE198_RS30525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_62040"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_189892471.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.2e-43, bitscore:
                     141.7, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHRIVVLGAGYAGAFAAGNLARRLSPADTEITVVNAEPDFVERM
                     RLHQLAIGQDVAFRKLADVFAGTGVRLRLARVTGVGPERRTVAVTGEDGDGELAYDTLL
                     YALGSSVAHHGVPGVAEYAFDVAGRSSALRLRERLAGLDGGGTVLVVGEGLTGIETATE
                     FAEARPDLSVALAARGELGAWLSPKARRHLRQAFDRLGITVHEHTGIEAVEPTRAIAAD
                     GTSIPSDVTVWSAGFAVHPIAAAGGLEVAETGQIVVDRTMRSVSHPDVYAAGDCAYAIG
                     ENGRPLPMSCASAGFTNMQATAAIIARLTGREVPTTGLKYHGNHISLGRRDAIFQMVDG
                     DVRSKSWYLGGRTAARLKSGVLKGAGWGIAHPTFGMPKRKRRLATAPDRSGVRVAA"
     gene            6344..7282
                     /locus_tag="IE198_RS30530"
                     /old_locus_tag="GCM10010381_62050"
     CDS             6344..7282
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012377640.1"
                     /locus_tag="IE198_RS30530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_62050"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_189892473.1"
                     /transl_table=11
                     /translation="MDSVAIDRFEASRGRLASLAYRLLGSAADAEDAVQDAFLRWQAAD
                     RERIEVPEAWLTKVVTNLCLDRLRSAQARHERAVGDWLPEPLLEGDPMLGPADTFEQRE
                     SVSLAVLTLMERLSPVERAAYVLREAFSYPHAEIAGILDITESASQQHVHRARRRVTAE
                     RRGGDEVDPASARRIVEEFLAAATSGRTERLVAMLTADATAVSDGAGLARRLLRYKTRE
                     RIASHVRAGLKPTPAKRRLAGGSPAFHIALVNGSPAVLAVIEDRVVGAVAFEVSDGKVA
                     SLRGIAAADRLARLNEAWGQHEPDAPVIHAW"
     gene            7856..8119
                     /locus_tag="IE198_RS30535"
                     /old_locus_tag="GCM10010381_62060"
     CDS             7856..8119
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007490456.1"
                     /locus_tag="IE198_RS30535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_62060"
                     /product="hypothetical protein"
                     /protein_id="WP_189892526.1"
                     /transl_table=11
                     /translation="MSWSDVLERGTADSSLTFARARWRQAGKFAWVAPRQTITAPTGEQ
                     YPLCATVYFKDFDDVVKPYFPSMDGMTEADDWYIGISGHPPQ"
     gene            complement(8284..8631)
                     /locus_tag="IE198_RS30540"
                     /old_locus_tag="GCM10010381_62070"
     CDS             complement(8284..8631)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE198_RS30540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010381_62070"
                     /product="hypothetical protein"
                     /protein_id="WP_189892475.1"
                     /transl_table=11
                     /translation="MGPHIRTCAVIHKAGRYTTLVSLSGWCGGVVLCPVATRTIHDVLG
                     DLPRADWPGVELTVHVRVDATTAEDLDCVGWDIVRLTTAAVGKARQPHGDGARMWMGSQ
                     GSTVPSTQRAA"
     misc_feature    complement(8708..8722)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.08"
                     /tool="antismash"
     gene            complement(8822..9508)
                     /locus_tag="IE198_RS30545"
                     /old_locus_tag="GCM10010381_62080"
     CDS             complement(8822..9508)
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004003263.1"
                     /locus_tag="IE198_RS30545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_62080"
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_229834512.1"
                     /sec_met_domain="Abi (E-value: 2.5e-20, bitscore: 65.0,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLLAVVVLPAANTLNGLLAPAWYVPVCAVAAALLVLIARRSGLA
                     WDDLGFGRAAARRGLRWGLVLVGAVLLVCLVGLALPFSREAFQDERAAGLSPEELVYRV
                     LVRVPLGTVLLEEIAFRGVLWAMVRRRWGPLWATVVSSVLFGLWHVQPSLGLTRANAAA
                     QAVFGAGQVGVALSVTAAVVGTALAGVLLCELRRRSGSLIPPVALHCALNSAGYALAWA
                     ASRWWG"
     gene            complement(10001..11017)
                     /locus_tag="IE198_RS30550"
                     /old_locus_tag="GCM10010381_62090"
     CDS             complement(10001..11017)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="IE198_RS30550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_62090"
                     /product="hypothetical protein"
                     /protein_id="WP_189892479.1"
                     /sec_met_domain="T1TS (E-value: 1.8e-71, bitscore: 234.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQELSFDLPFPSRISQDVKSAAAHHITWIQKHGLLGQGSLGEYCR
                     WDVPGVAARFWPHASGADLALGTDVAGWFLLVDDQFDGPLGMQPGRVAQIIQQLIDVVH
                     SPRGAVPRGNPTPAASGLASIWSRQVRGMSASWQQRSSRNWKDFLNAYTSETINRHSGI
                     VPDVDTYLRLRHKTGLENVLIDCAERIGHYELPEAVFSMPEIQKMHNATVQVVNIIQDA
                     FSVSKEEARGDFHNLVLVLQHHRHYSRQEALAETRSTVRRYTDEFLHLKSQLPALFDAA
                     ALPVPDRESAYVFIDDLQAQMRACHDWCRTSHRYSRVIRARPDQPTYLEEMHMEGLG"
     misc_feature    complement(10820..10822)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(11006..11008)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11449..13269
                     /locus_tag="IE198_RS30555"
                     /old_locus_tag="GCM10010381_62110"
     CDS             11449..13269
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF018884.5"
                     /locus_tag="IE198_RS30555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_62110"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_189892481.1"
                     /transl_table=11
                     /translation="MTDVGFQSWPSTDQSITGRTTSALPSPARRTGEHGAKDTGMDHKS
                     SNSLFQPSAGPVQAGFFCWDVATGEIDCDPPTYHLHGLPEDSPAQLETFLSRIPESDLP
                     EFIGALQSMAEAGGNYQIAYRIALGEGGWRSLEARGRVLADAAGVPTRMVGVVMDTTAA
                     HERQEAEKRRLCERATRNLRMQQLTAALAAAVTVKDILAATQVGLQDFGASGLAVVASQ
                     RDGLSIVASCGYDEEELAAVCDADTGTGSLLQDALVRHAPVFVASVTDLAAAYPQSAAQ
                     QTAEWSCRAWAAIPMADSRGPIGVCLMGFPSPREFGPEERALLVALAGLLAQSLERAGM
                     YESQHALATELQRGILPPGPLSAPGLTIAARYQAATSDMRIGGDWYDAICLPDGAVALV
                     IGDVQGHSVHAASLMGKLRTAIHAYASEGHGPAAVLARTNRLLVEFNPDPDRAMLATCC
                     YLLIRPAEGMLEACTAGHLAPVLIAPGEPPRLLDIAGGLPLGVDPQAQYPTERIPIRPG
                     SVLAVTTDGLLETAGGDIGVAIEAFLTGLAGAATADLEVLADELLAGAHRAPRRSDDIA
                     LLLARLIGPQRADEPSATGRATQTEAPAER"
     misc_feature    13817..13834
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.85"
                     /tool="antismash"
     gene            13957..16077
                     /locus_tag="IE198_RS30560"
                     /old_locus_tag="GCM10010381_62130"
     CDS             13957..16077
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008737937.1"
                     /locus_tag="IE198_RS30560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_62130"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_308426880.1"
                     /transl_table=11
                     /translation="MVDTRASTSDVPDRPPQPAVGYAGVFRDLLPIALWRADSQGRIVQ
                     WSLAAKDLLGYAPEELLGRYGTPILVPEANRELADELARKVRLGEAVLGCLPVRHRDGH
                     IVEMEMWICPAADAQGRTGLLAIAAETSAVVHMRDSLAALEGLFTQSPIGLAMLGPDLR
                     YLRVNDALVRMNGVPAAEHIGKRVGEVAPGVNAAELETVMRQVLDRGEAVVDFRRAGRT
                     PADPDHDRTWSCSYAPLLGGPGQPLGLIASLIDITEGQQAHVRAEQAGRRFALLAEAGT
                     RIGTTLDLRKTAEEVVQVLVPQLADSADVHLLDRVLAPDQAAASSHGVARRMAVLYTDP
                     AAPAEELAVGKTYQVPPGSVYERVIDEGRPLNLYLTDIEPLVTDPGSEQLRDYLRTRVG
                     SARMVPLLARGSPLGAVLVTRTRDREPFDDQDIVLIDELVARAALNIDNARMYTSQRHA
                     ALTLQRSLMNASLPTVTGLELTGRYLPASDQEVGGDWFDVIALPRGRTGLVIGDVMGHG
                     IHAAAVMGQLRTAVRTLARSDIAPAQLLYALDATVADLGENAMATCVYAVHDPATSSCL
                     IARAGHPPPAVADAQGTVAFLEGPSGTSLGAGGQGFTDERVSLPPHSLLVMYTDGLIET
                     RDKDLDQGMQQLSQALRHPHVPLEEICDHLLRRLLPPMVHDDVALLLVRPQPESRQAPA
                     NPAEPPKRTSTS"
     gene            16495..16659
                     /locus_tag="IE198_RS30565"
                     /old_locus_tag="GCM10010381_62140"
     CDS             16495..16659
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE198_RS30565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010381_62140"
                     /product="hypothetical protein"
                     /protein_id="WP_189892483.1"
                     /transl_table=11
                     /translation="MTDRGNGYVIPEPEEEPDFADEHSRPTYADEPSTEDPDESVPSGE
                     GGDGGMDPT"
     misc_feature    16762..16776
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 24.03"
                     /tool="antismash"
     misc_feature    complement(16777..16791)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 23.96"
                     /tool="antismash"
     gene            17455..17856
                     /locus_tag="IE198_RS30570"
                     /old_locus_tag="GCM10010381_62150"
     CDS             17455..17856
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025384.5"
                     /locus_tag="IE198_RS30570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_62150"
                     /product="DUF4234 domain-containing protein"
                     /protein_id="WP_229834516.1"
                     /transl_table=11
                     /translation="MSGRAGKPRNILLVWLIWPLITLGVYHFVWYYKVNREARDFDPRI
                     EVNPAYAVLAILIGWLVIVPPFVSVYNTGQRIAEMQKSAGMQPSCNPWIGLILMIIAGL
                     HALYYQHELNQIWTHYRNPAEGQQVPLAV"
     gene            complement(<18333..>18556)
                     /locus_tag="IE198_RS35750"
                     /pseudo=""
     CDS             complement(<18333..18556)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003952962.1"
                     /locus_tag="IE198_RS35750"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="site-specific integrase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MCPAWVKDVRTRARRRDRVRVRTSCWKPSTGTPAPAAPAPTAQGP
                     HSRGRVRHAPAPGGGGVSLATSARTPGRH"
     misc_feature    complement(18564..18579)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 21.1"
                     /tool="antismash"
     gene            18691..19056
                     /locus_tag="IE198_RS30575"
                     /old_locus_tag="GCM10010381_62170"
     CDS             18691..19056
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE198_RS30575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010381_62170"
                     /product="hypothetical protein"
                     /protein_id="WP_189892485.1"
                     /transl_table=11
                     /translation="MEELSEFLQEPVILVESLKECLVDDDAFSCLIRSSPPQGRAFQLS
                     WEGILGMEPIDGKPHASVSLFLYSRNRRLALSGHAEGSVLEIVYEGSLEHGGRWANPCW
                     DQDEFGEYLTFETYGEC"
     misc_feature    19467..19482
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.86"
                     /tool="antismash"
     misc_feature    20352..20367
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.63"
                     /tool="antismash"
     misc_feature    complement(20388..20401)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.33"
                     /tool="antismash"
ORIGIN
        1 ccttccccgg agccgggctg cccgccgccg ccctctatct gatcctgcac gccatcactg
       61 gcctgtgacc gcagcggagg cccacgatgc ccaccccacc cactcccaag tcgggcaagc
      121 caccaggcgc cggcctcccc gacggcctcc ccgtgccagg ccgcttcagt catctgcacc
      181 ccgacgacgg cgcctgcctg atggaggagg cctccctgct ggccaccggc cgcttcaccg
      241 accgaccgcc cggcacgcat ccggtactcg cggcgctcgc ccgtgcggtc aacgacgccg
      301 tcgacgacgc cacccgccac accctgtggc cgctggccgc cgatcttgcc gacgccaacc
      361 ccgccgaccg tgcctacggt ccgctattgg tgggcacggt cgtggacgcc gccctccgcg
      421 tgcggcccga gtctcggcgc ctgaaatggc gcagcgcggc ctgccacgcc cgggcccacc
      481 ggctcgcccg agcccgtacc gcgacgacac cggcccgcat cgccgacatg ctgtggtggc
      541 gcggccccgg ccaccaccac ctcgaacacg ccctccgcgt cctgctcacc gcccccgacg
      601 ccgaccagcg cctcgcccgg ctccttcacc gggccgtgag cgaggcccgg gtccgaacca
      661 ccgtggaaca ggcaccgacc cacgcggaga cctcctctca gcgcggatga atcccggcct
      721 gcggagccgg gccggctggg caggtgggtc ggccgaggca gaccaccagc aggcagtgct
      781 ggtccggttg tgtggtcgtc ggggggctcg gctgggacgc tccctggtcc gtgcctcggt
      841 ggccgccgcc gtcgggcgcc gctgctgggc ccgtgtcgct gcggtcggag gccgccggag
      901 cgggtgccgg tggcgaggcc ggcggctgct gtggtgaggt cgccgccgat gcgggacggg
      961 gggacgccgg acgagacgag gccactgtca cgagcggcgg aagctcacct cggcccacgt
     1021 caggtcggcg gtgtcctcca gcgtgtaggt cccgggttcc agagcggcgc gcagcgcgtc
     1081 cgcccggcgc gtgtctccgg gcatgacgac caggctgagg cctggttgtc gtgccccgtc
     1141 ctggatgctg agcaccatct cagcaggggt ctcctgcccg cgaagggccg cgctgagaac
     1201 gctgcgcacc agtgccgtcc gggccgctgc gtccacgggc ggcacgtcga ggtccgcatg
     1261 ggcgtggacg gtcaccacac agcccgactc ccgggcaccg ccgaccagtt cacgcagggg
     1321 ccggtcgaac acccctggca ggtggagttc gtcgcggatg gactgggcca gccggtccgc
     1381 ccgtccccgc agtgcacccg gatcgtgcgt ttcgccggtg gccaccgagc ggaggaacgg
     1441 cagcacctgc tcgtcgatct cggcgagccg tctgcgatgc tgcaccgctc gcgcccgggc
     1501 cgccgactcg gtcgccacga ccaccatgcg gtgccggtgg gcgtccagga ccgcgccgcc
     1561 caaagtgacc agtgtgcgtc tgatgaccag ccccatcacg acgcccatcg ccggagcgag
     1621 catcgccggc agcgccatgg cgaccgcacc cgtcggtgtc gccgcggccg gcggatcggc
     1681 ggccaccagg atgactatgc ccgcctcctc gcacgccagt gccagtgccg tctgccgcag
     1741 cggacgcacg acgacgagca gggtcagaag cggcgtcacc gcgccgatcg gccacgaccg
     1801 atagtccgtt atgccctccg gcgggatcac cagcaggctg ctcaccgcgc cggcggtcgc
     1861 cacgaccagc agcacggcgg ccaccttcgc gctgatccgg cggtgtgccc ggccgagcag
     1921 gatgcacgta gccgcggtca gggccgcgta ccacaccaga tgcgccacca tctggggcat
     1981 gtgcacggtc cggaccaccg cgacgacgac catgaccgcc agatacggca gacacaccgc
     2041 ggccagcggt gcacggacgt cccccaccgc tgcccgcagc gtctccagcc gcccgcgtcg
     2101 gcccgccggc acaccaccgc ccggggcggc caccggcgag ctccaccgca gacgcaccgt
     2161 ggtaccgcgt ccgggttcgc tgtggacgtc ggcctccccg ccgacgtccg tcatgcgctg
     2221 acgcaccgag tcctgcagtc ccacggccgt cttgcggacc tgggagacgg agaacccctt
     2281 gccgttgtcg cagacggcca gttccagggc gcgccggtct ccgctcagcc ggacgtggac
     2341 gtgcgaggcg ccggcgtacc gcacattgcg cagcgcctcg acggccgccc cggtacacgc
     2401 ggcagccacc tcgtgcggca gcggcaatcc acccgacggg aagtcggtcg agacccgcgg
     2461 gcgggggagg ccaccgacgg aggtcgccac gagccccgac agcaacgaca cgaggtcggt
     2521 ctcggcgccg tcctcctccg gggccgcccc ggcggtgagc ccggccaccg cacgacgggc
     2581 ctccgcgcgc tgctcgtcga cggggacgcc gcgtgtgccc gcggctcgaa gcgcggcacc
     2641 gacgtcgtca tgaagcagac gctggaagtc ccgttggctc cgtcgcgcgg cctgttcccg
     2701 cgcggcggcc tcgctcgcgt ccaggtcctc gcgtacggcg gcgtcggctc gctccccggc
     2761 gccacgcatg accggggcca gcacggccgc ggccacaccc ccggcgaacg gcggccagat
     2821 cccctccaga gccgtccaca tgccctcgtg ccacccggcc gccacctgtg ccgccagaca
     2881 aaccacggcc aggggccggc cccatacgcc gggaaggtat gccacggcga ggagaaccgc
     2941 cgtgaccgtc accatgcaac gcagtcccgt tacgatctcg tcgggctgct cgagcgcgta
     3001 cgcggcgtgc acggccagtg ccacggccac cgccgtcagg gcgtcgtacc gcccgatccg
     3061 tacgaaggca ccccggtagg cccaggccgc ggtgcacccc gcgaagagca ccgctgccgc
     3121 cgatgtcagc ggatggagcc cgaccgaccc ggagacgacc agcgacgcca ccacgatcca
     3181 ccaggcgacg acgaacagca gggccatgcc ggcgaacgac cgccggagcg cgctctccac
     3241 gccggagcgg taggtgccgc gtcccgtcac tccgccacgt ccgggccgat gtcgatgtgc
     3301 ccgtccagca ccgagcgcca caccagctgg gagttgtagt cgagcttctt gccgccgcct
     3361 ttggcgaacg cgtcgatggc acgcctgcgg tgggtcttca cggtgtcctc cgacatgtac
     3421 aggcgcttgg cgatgtccgc cggcctcaat ccgcgggcca gcagctccag cacctcgagc
     3481 tgcctcgcac tgagacggac cttcccccgc tggtcgttga cgatctggtg ggccagccgg
     3541 ctggagacgt acgccttccc gctgtgcgcg gccccgatgg cctcgacgag ctgagcgtcc
     3601 gggtcctcct tcagcaccag tcccaaggcc ccggcctcga tacctctgcg gaccaccacg
     3661 gggcggtgct cacggctgaa cagcatgacg tgcgggcccc attcccgcag acgcccgacg
     3721 ttctcgccga cgtcgcttcc gtcgctcaac tcgatgtcca gcagtacgac ggtgggaacc
     3781 accgtcaccc tcgagggcag gtccgtgacg gtctcggcgc tgcccaccca tgtgacctcg
     3841 ggcgccaact cggtgaggca ggcacgaatg ccgtgcagga tcaccgggtg gtcgtcgacg
     3901 gcggccagga gcgccccggc cgctgtgtcc tcactgctcg caccctgcgt accgttcatc
     3961 cttctccctc acgatgacgc ccctgaaagc ctgaggaagg gtctaccacc gggcggcggg
     4021 cgagtatgtc ccctttcccg gggacataca gtgacgtccc gccgaagcga aggtaggtga
     4081 accggccggt ccccgcagcc acttggcgag tggccgcggt gccggcgcac cacacaccca
     4141 cagatcagga gcagaccatg ggcaggttca ccaagcgggt cggcgccttc gagtccccgc
     4201 actcggtcgc cgacacgatg acgatcctct acaacggcgt gtccgagcag ctcagcaacg
     4261 ccacgccgac tgtctcagag cccggcctgg ccgcctcgat ctacctgacc cgcttcgacg
     4321 acagcggcct gacggtgacc gcgggcaaca ggatcgagac gtacttccgc ttcatggtcg
     4381 acgtcacgtc caacggcagc ggctgcgtcg gtgaggcgta cttcgaccgg cgcatgggag
     4441 cgatcaaccg ctggatgggc aacgccatgg ggctcaccgg cggcctctcc ctcacgttcc
     4501 agcaatgcag tatccgcacc cgcggctgga ccatcgcctg attcgccgag gcggaggagg
     4561 aacgaacatg agccaggtca agtgcaggtg cggccagaca ctggagaagt gctgcacacg
     4621 cggttgcagc cgctgcacct cgggataccg ctgctcgaca catggcaaag actgggcccg
     4681 cacgaccggg ggcggcctgt tcagctccgg ccgcacgggc agcggcgcca gatgtcgcaa
     4741 ggaccacacg ccggtcgtca actgtcctca ctgcaatggc cgggcaggca gaacatgcag
     4801 cacctgcggc gggaccggcc agacctgtcc gacacacggc cagttctggc agtgaccgcc
     4861 tgccgggccg ctgacgcggc gaacggtggg cctgccgtga tcgcaggccc accaccgtcg
     4921 gccaccgacc cggcgcaggc cgccgaggcg ctctgcgagg tcgccgcggg cgcagagatc
     4981 cccagtcggc cagcgccccg tttcgactgc ccaagacagg ccgcgcctgt cgtaggccca
     5041 gccgctcgtc ttggttcggt gacccgcgtc acacccggcg gctgtcagca atcggggcgc
     5101 cgtctcgttc aaggggcacg cgaacgagac aggagcaacg caatgaagca ccgcatcgtc
     5161 gtactcggcg ccggatacgc cggggccttc gccgccggaa acctggcccg ccgcctttcc
     5221 cccgccgaca ccgagatcac cgtcgtcaac gccgagcccg acttcgtcga gcggatgcgg
     5281 ctccaccagc tggcgatcgg ccaggacgtc gcgttccgca agctcgccga cgtgttcgcc
     5341 ggtacggggg tgcggctgcg cctggcgcgc gtcaccggcg tcggccccga gcgcaggacc
     5401 gtcgccgtga ccggcgagga cggcgacggc gagctcgcgt acgacacgct tctctatgcg
     5461 ctcggcagct ctgtcgccca ccatggcgtc cccggcgtgg ccgagtacgc cttcgatgtg
     5521 gccggccggt cctcggcgct gcggctgcgc gagcgcctgg ccggcctgga cgggggcggc
     5581 accgtgctgg tcgtcggtga ggggctgacc ggcatcgaga ccgccaccga gttcgccgag
     5641 gcccggcccg acctgtcggt cgcgctcgcc gcccgcggcg agctgggcgc ctggctctcc
     5701 ccgaaggccc gccgccacct gcgccaggcc ttcgaccggc tcggcatcac cgtccacgag
     5761 cacaccggca tcgaagccgt cgagccgaca cgtgcgatcg ccgccgacgg tacgtccatc
     5821 ccgtccgacg tgaccgtgtg gtcggccggg ttcgccgtgc accccatcgc tgccgccggc
     5881 ggcctggagg tcgccgagac cggccagatc gtcgtcgacc gcaccatgcg ctcggtctcg
     5941 cacccggacg tctacgccgc cggtgactgc gcctacgcga tcggcgagaa cggccggccg
     6001 ctgccgatgt cctgcgcctc ggccggcttc accaacatgc aggcgaccgc cgcgatcatc
     6061 gcccgcctga cgggccgcga ggtcccgacc accgggctga agtaccacgg caaccacatc
     6121 agcctcgggc ggcgggacgc gatcttccag atggtggacg gggacgtccg gtcgaagtcc
     6181 tggtacctgg gcggccggac cgccgcgcgg ctcaagtcgg gcgtgctcaa gggggccggg
     6241 tggggcatcg cccacccgac cttcggcatg ccgaaacgca agcgccggct ggccaccgca
     6301 ccggaccggt ccggtgtacg ggtcgccgca tagcctgttc cgcatggaca gcgtcgccat
     6361 cgatcggttc gaggccagcc ggggccggct ggcctcgctc gcgtaccgtc tgctcggctc
     6421 ggcggccgac gccgaggacg cggtgcagga cgcgttcctg cgctggcagg ccgcggaccg
     6481 ggaacgtatc gaggtgccgg aggcgtggct gaccaaggtc gtcaccaatc tctgcctcga
     6541 ccggctccgc tccgcgcagg cgcgccatga gcgcgccgtc ggggactggc tgcccgagcc
     6601 actcctcgag ggcgacccga tgctcggccc tgccgatacc ttcgagcagc gcgaatcggt
     6661 gtccttggcc gtactgaccc tcatggagcg cctctcgccg gtcgagcggg ccgcttacgt
     6721 cctgcgcgag gccttctcgt acccccacgc cgagatcgcc gggatcctcg acatcaccga
     6781 gtccgcgagc cagcagcatg tccaccgggc ccgacgccgg gtcaccgccg agcgtcgcgg
     6841 cggcgacgag gtggaccccg cgtccgcgcg ccgcatcgtc gaggagttcc tcgccgccgc
     6901 cacgtcgggg cgcaccgaac ggctggtggc gatgctcacc gccgacgcga ccgcggtctc
     6961 ggacggcgcc ggactggcca ggcggctgct gcggtacaag acgcgcgagc gcatcgcctc
     7021 ccacgtgcgg gccggcctca agcccacgcc ggcgaagcgg cggctggccg gcggctcccc
     7081 cgccttccac atcgcgctgg tcaacggctc cccggccgtc ctcgccgtga tcgaggaccg
     7141 ggtcgtgggc gccgtggcgt tcgaagtcag cgacggcaag gtggcgtccc tgcgcggcat
     7201 cgccgccgcg gaccggctcg cgcgcctcaa cgaggcctgg gggcagcacg aacccgacgc
     7261 gccggtcatc cacgcatggt gaccagagcc accggtatcc agtgacctga ctcggagcga
     7321 ggacggcatc ccttcgaccg cgcgccgcac agcagcacgg tctcccgaat cggttggtat
     7381 cgggaagcac gggcggcttt tgatcgcgcg gctcgctgct gtggctaccc ggagggttcg
     7441 gcgccggcaa cgggcagcac cgaagtcgcc ttcggctggg ggagttcgcg ggttggtcgt
     7501 tgcatcccaa tgggggtact tcctcaaact ctgaattgtc agcgcctccc gccgctgacg
     7561 gggctccagc tgaagccgtg cgggaagttc aacgagagcc tcggaagaag ccgccgcagg
     7621 gctgtcgcga ggccatcaat gaggttcgcg cccaccaggc ggcgcagcag acagccttgg
     7681 aactcgcagc catcacccag cgccagtccc gtggctcgcg ggctcggggc agcaggggca
     7741 ccacggacag gcagacgaat cgtgcagaag tgcggcgcta gcggaatgcg gtgggagttg
     7801 tcaactcccc tccttcttgg tcggaacagc gctctacgct gacctcgtga cgtacatgag
     7861 ctggtcagat gtgctggagc gaggaactgc ggattcgagc ttgaccttcg cccgggcccg
     7921 ctggagacag gcagggaagt tcgcgtgggt ggcgccgcgt caaacgatca cggctccaac
     7981 aggtgagcag tatccgctgt gcgccacggt gtacttcaag gactttgacg acgtcgtcaa
     8041 gccgtacttc ccgagcatgg acgggatgac cgaggctgac gactggtaca taggaatttc
     8101 cggccatcca ccgcagtagc cgtgctcggt acgcacgcac cctcgtctgc ctggtgcccg
     8161 tgagggggga gtaggccacg ctgccggtcg cccaaccggt tgtcggtacc gccaggcacc
     8221 gacagggcct gcgcagtctg cgacagggac gctgcctccg gccggtccaa tgaggctgcg
     8281 tggtcaggcc gccctctggg tggacggcac cgtgctccct tggcttccca tccacattcg
     8341 ggctccgtca ccgtggggct gccgggcctt ccctacagcc gcagtcgtca accggacgat
     8401 gtcccagccg acacagtcca ggtcctcggc tgtggtggcg tcgacccgga cgtgcacggt
     8461 gagttcgaca cctggccagt cggcgcgggg caggtcgccg agcacgtcgt gaatggtgcg
     8521 ggtggcaacg gggcacagca ccaccccgcc acaccagccg ctgagagaga cgagggtcgt
     8581 gtaccgccca gccttgtgga tgacggcgca ggtgcggatg tgcgggccca tggcgggcgc
     8641 cccctcatgc agtgcgtgcg gtgggggatt ccgggatcgt caccggatgc gtggaagatg
     8701 tcaaggcaat gtacagaaaa ggtgcgcctc gtccgtccgg caggctcgag agcccggaat
     8761 ggatggatgg cgcgcccatc ggcgaagttc aaagcagccc cgggccgccg gcctggggcc
     8821 cttagcccca ccagcgactc gccgcccagg cgagtgcgta acccgcactg ttgagggcgc
     8881 agtgcagcgc cacgggtggg atgaggctgc cggagcggcg gcggagttcg cagagaagca
     8941 caccggcgag ggcggtgccg acgaccgccg ctgtcacgga cagggcgacg ccgacctggc
     9001 cggctccgaa gaccgcttgg gccgccgcgt tcgcgcgcgt gagcccgagt gacggctgta
     9061 catgccagag cccgaagagc accgaggaaa cgacggtggc ccacagaggc ccccaccgtc
     9121 gccgaaccat ggcccacagc acgccgcgga atgcgatctc ctcaagcagc accgtgccga
     9181 gcggtacccg gaccagtacg cggtacacca gttcctcggg agacaggccc gcggcccgct
     9241 cgtcctggaa tgcctcccgg ctgaacggca gtgccaggcc caccagacag accaagagaa
     9301 cggctccgac gaggaccagg ccccagcgca gaccgcggcg ggcagcggcc ctgccgaacc
     9361 ccaggtcgtc ccaagcgaga ccggaccggc gggcgatcaa cacaagcagc gcggccgcaa
     9421 ctgcacagac cggcacgtac caagcgggcg cgagcagccc gttgagggtg ttcgcggccg
     9481 ggagcaccac gacggccaag agcagcatcc acatggccgc acaaggattg ccgacgttcg
     9541 cgagagcggc ccgcaatgcg ctgttccacg gcgcgccgcc tatcggtcgc ggacggtgag
     9601 gaattcgagt gactgccagg cacgcaacgc gaccaccgct gctgtgcaac agctgctgga
     9661 ggctgtcagg agtgcggtgg cctgcccctt cggcgagctg ccagccgttc ttgcgtgttg
     9721 cccgcctggt ggccgcggcc gcggtcgcgg ggcagctccc attcgactcc gaccgcgagc
     9781 accggctgtg ccccgagcgg gccatcggcg cgctcaatgc cggcttcggc ctccggcacc
     9841 gtgggccccg cagcgactca tccgaaggcc gtttgaacgc ctgcacttct tcatgacccg
     9901 caatggggct cccggccaga tgctcgcgca ggggcgagag gacgcggggt cctggatggc
     9961 tgcgatcacc acgcagggga cggtagcgtc acggtgcctg tcatccgagt ccttccatgt
    10021 gcatttcctc gaggtaggtg ggctggtcag gccgcgcgcg gatcactcgg gagtagcggt
    10081 gggaggtgcg gcaccagtcg tgacaggctc tcatctgcgc ctggaggtca tcgatgaata
    10141 cataggcgct ttcccggtcg ggcacgggaa gggcggcggc atcgaaaagt gcggggagct
    10201 gcgatttgag gtgcagaaat tcgtcggtgt agcggcgtac tgtcgatcgg gtctccgcca
    10261 gggcttcctg gcgcgagtag tgccggtgat gttggagcac gagcaccagg ttgtggaagt
    10321 cgcccctggc ttcctccttg gacacggaga acgcgtcctg aatgatgttg acgacctgga
    10381 ccgtcgcatt atgcatcttc tggatttccg gcatggaaaa gacggcttca ggcaattcgt
    10441 aatgaccgat gcgttcggcg cagtcgatca acacattttc cagccctgtc ttgtggcgca
    10501 gtctgaggta cgtgtcgacg tcgggcacga taccgctgtg gcggttgatg gtctcgctgg
    10561 tgtaggcgtt gaggaagtct ttccagttcc gggacgaccg ctgctgccac gaggcggaca
    10621 tgccgcggac ctggcgagac catatcgagg ccagcccgct cgccgccgga gtggggttcc
    10681 ccctcggcac cgctccgcga ggtgagtgca cgacatcgat gagttgttgg atgatctgtg
    10741 cgactctgcc gggctgcatt cccagcggtc catcgaactg gtcatccacc aggaggaacc
    10801 aacctgcaac atctgtccct aacgccaggt ctgctccact cgcatgtggc cagaagcggg
    10861 cagcaacgcc cggtacatcc catcggcagt actcgcccag ggatccctgg cccagtagtc
    10921 cgtgcttttg aatccaggtg atatggtgag ccgctgccga tttgacgtcc tgactgatcc
    10981 gcgaggggaa gggaaggtcg aaagataatt cttgcacagc gctctccttg ttcagatttc
    11041 tttatgtggg ttacggtggc agtggctcgg gcgcatcatc accccaaccc ggcgctcggt
    11101 gcgattatca gagcgcgaac cggtgatcgc gtccagagtg gtagcacaac cccggcgtag
    11161 ggaagcaccc acacgacctg ccccgcgccc ttcactcccg gagtcgttcg tcaccgtgtc
    11221 gacgctcctt acaccgggtg atgcgccgcc ggcgcggccc cggcaccccg gcgaacagca
    11281 tccgcactcg ggacacctct tggcgagcag gtccagtttc tgcgacagga tcaccctttc
    11341 aggtgcctgg ctgatcgggt ctccgcatgg cgggcatcgt ggttctacgc tgatatctcg
    11401 tcacatgact ctcagggaga cgtcgttgcc tacagcgggg agtgatcggt gacagatgtc
    11461 ggattccagt cctggccgag caccgaccag agcatcacag ggcgcaccac ttccgcgctg
    11521 ccctcccccg cccggcggac gggtgagcac ggtgccaagg acaccggcat ggaccacaag
    11581 tcgtcgaact ccctgttcca gccgagcgcc ggcccggtcc aggctgggtt cttctgctgg
    11641 gacgtcgcca ctggggagat cgactgcgat ccgcccacct accacctcca cggcctgccc
    11701 gaggacagcc ccgctcaact cgagaccttc ctgtcgagga tcccggaatc cgatctgccc
    11761 gaattcatag gtgcactgca gtcgatggcg gaggccgggg gcaactacca gatcgcctac
    11821 cgcatcgcct tgggtgaggg cggctggcgc tcgctggaag ctcgcgggcg tgtactcgct
    11881 gatgcggcgg gagtaccgac aaggatggtc ggggtggtga tggacaccac ggccgctcat
    11941 gagcgtcagg aagccgagaa gcgacggctc tgcgaaaggg cgacccgcaa tctgcggatg
    12001 cagcagctca ccgccgcgct cgcggccgcc gtgacggtca aggacatcct ggccgccaca
    12061 caggtggggc tgcaggactt cggtgcgagc gggctcgccg tggtggcgtc gcagcgcgat
    12121 ggactgtcca tcgtggcctc ctgcggctat gacgaggagg agctggccgc tgtctgcgat
    12181 gcggacaccg gcacgggctc tctgttgcag gacgcccttg tgcgccatgc tccggtgttc
    12241 gtcgcctccg tcacggacct ggccgccgcg tacccgcagt cggcggcgca gcagaccgcg
    12301 gaatggtctt gccgggcgtg ggcggcgatt cctatggcgg attcccgggg gccgatcggg
    12361 gtctgcctga tggggtttcc ttcgccccgg gagttcggtc ccgaagagcg ggcgctgctg
    12421 gttgcccttg ccggactgct cgcccagtcc ctggagcggg cgggaatgta cgagtcgcag
    12481 cacgctctgg ccacggaact gcagcgcgga atcctgcccc ccggccctct gtcggcgccc
    12541 ggtttgacga tcgccgcgcg ctaccaggca gccacgtcgg acatgcggat cggcggtgac
    12601 tggtacgacg ccatctgcct tcccgacggc gcggtggcac tggtgatcgg agacgtccaa
    12661 ggccacagcg tgcatgctgc ctccctgatg ggcaagctcc gcacggccat tcacgcctat
    12721 gcaagcgagg gtcacggtcc ggcggccgtt ctggcacgga cgaatcgcct gctggtcgag
    12781 ttcaacccgg atccggaccg ggcgatgctc gccacctgct gctatctgtt gatccgccct
    12841 gccgagggga tgctcgaggc ctgcacagcg ggccatctgg cacctgtcct gatcgctcca
    12901 ggtgagccac cgcgcctcct cgacatcgcc ggtggcctcc cgctcggtgt cgacccgcag
    12961 gcccagtacc cgaccgagcg gatcccgatc cgccccggca gcgtgttggc agtcaccacc
    13021 gacgggctcc tggaaaccgc gggcggagac atcggcgtgg ccatcgaagc atttctgaca
    13081 gggctggcag gagccgcgac ggccgacctc gaggtcctgg ccgacgaact ccttgccggg
    13141 gcccaccggg caccgcgccg cagcgacgac atcgctcttc tgctggcccg cctcatcggc
    13201 ccccagcgcg ctgacgagcc atctgccaca gggagggcca cgcagacaga ggcgcccgcc
    13261 gagcgctgaa gctggaaaat tgcgccgagc ccgacggtcg gaccgcttct acggcgcccc
    13321 cgacacggtg ccgacgacgg cctcgtacga cgatgccgcc ccttgggttt cagacggaca
    13381 tcacccgctc atccggcgcc gccctcggcg tgcggcaggc ggctgtcccg tacggcggac
    13441 cccgctgccg gtgtggttct tacgggcgga cgagtcgaag acccggcgcc ccaccgtgat
    13501 cctcatgaat agcagtgacg ggcagaatgt cgatatgtag acctgcagcg ttccggtcgc
    13561 gctggacctc ggctggaacg ccctcggcta cgaggggccc ggccagggca gctgctcttc
    13621 gtggaccagg tgatcttccc gctggcctgg gagaaggtca aaagtcccct catcgactgg
    13681 gactgccggg tcctcctgat gacagggagc agaaagtggg cggatacggt cgcggtgggg
    13741 agcgattggt cggcccgttg ccgcgaagcg cgggccgccg ctgcgtttgt ccacgtcagc
    13801 gcctcggata gcctggttgt tagcagtttg tgttcgggga tcctgtgcct gaggaccttg
    13861 cgtctgaggg gctgaaccga tggtcgtggg cggcggcctg gcgccggacg agcggtcggc
    13921 gagcggagcg cccctcacgg gcagggatgg gtcactgtgg tggacacgcg cgcgtcgacg
    13981 agtgatgtgc cggaccggcc gcctcagccg gcggtcgggt acgcgggtgt gttccgtgat
    14041 ctgctgccga tcgcgctgtg gagggcggat tcgcaggggc gcatcgtgca gtggtctctc
    14101 gccgccaagg atctgctcgg ctacgcgccg gaggagctgc tgggacggta cgggacgccg
    14161 atcctggtgc ccgaggcgaa cagggagctg gccgacgagc tggcgcggaa ggtcaggctg
    14221 ggcgaagccg tgctcgggtg ccttccggtg cggcaccgtg acgggcacat cgtggagatg
    14281 gagatgtgga tctgcccggc cgcggacgcg cagggtcgga ccggtctcct ggccatcgcc
    14341 gccgagacct ccgcggtggt gcacatgcgg gactcgctgg cggcactcga gggactgttc
    14401 acccagtccc cgatcggtct ggccatgctc ggccctgact tgcgttacct gcgggtcaac
    14461 gacgccctgg tgcggatgaa cggcgtcccc gcggccgagc acatcggcaa gcgggtgggc
    14521 gaagtggcgc ctggggtcaa tgccgcggag cttgaaacgg tgatgcggca ggtactggat
    14581 cggggggagg cggtggtgga cttccgccgc gccggtcgca ccccggccga ccccgatcac
    14641 gaccggacct ggtcctgctc ctacgccccg ctactcgggg gccccggtca accgctgggg
    14701 ctgatcgctt ccctgatcga catcaccgaa gggcagcagg cccacgtccg ggccgaacag
    14761 gcgggccggc gcttcgccct gctggccgag gccggcacgc gcatcggaac gaccctggac
    14821 ctgcggaaga ccgccgaaga agtggtgcag gtactggtgc cccagcttgc cgactcggcc
    14881 gacgtgcacc tgctggacag ggtgctcgcc cccgatcagg ccgcggcgtc ctctcacggc
    14941 gtggcgcgtc gtatggcggt tctctacacc gatccggccg ccccggcaga ggaactggcg
    15001 gtgggcaaga cctaccaggt cccgcctggc tcggtgtacg agcgagtgat cgacgaggga
    15061 cgtcccctga acctctacct gaccgatatc gaacccctgg tcaccgatcc gggcagcgag
    15121 cagctgcgtg actaccttcg cacccgtgtg ggctcggcgc gcatggtccc ccttctcgcc
    15181 cggggcagtc cgctcggggc ggtgctggtg acgcgtaccc gtgaccggga gccgttcgac
    15241 gaccaggaca tcgtgctcat cgacgagctg gtggcccgcg cggcactgaa catcgacaac
    15301 gcacgcatgt acaccagcca gcgacatgcg gcgctcaccc tgcagcgcag cctgatgaac
    15361 gcctcgctgc cgacagtgac ggggctggag ctcaccgggc gctacctgcc cgccagcgat
    15421 caggaggtcg gcggtgactg gttcgatgtc atcgcgctgc cgcgcggcag gacagggctc
    15481 gtcataggag acgtgatggg gcacgggatc catgccgcgg ccgtcatggg gcagctgcgc
    15541 accgctgtgc gaacgctggc tcgcagcgac atcgcaccgg cccagctgct ctacgccctg
    15601 gacgccaccg tggccgacct gggcgagaac gcgatggcga cctgcgtcta cgccgtccac
    15661 gatccagcca ccagtagctg tctgatcgcc agggccggcc atccaccgcc ggccgtggcc
    15721 gacgcccagg gaacggtcgc gttcctggaa ggcccctcgg gtacgtcgct aggggcaggc
    15781 ggacagggct tcaccgacga acgtgtttca ctgcccccgc acagcctgct ggtgatgtac
    15841 accgacggac tcatcgagac ccgcgacaaa gacctcgacc agggcatgca acagctctcc
    15901 caagcccttc ggcaccccca cgtcccgctg gaggaaatct gcgaccacct cctgcgccga
    15961 ttgctgccgc ccatggtcca cgacgacgtg gcgctgcttc tcgtcaggcc ccagcccgag
    16021 tcccgtcaag ctcccgccaa cccggccgaa ccgccgaagc gcacgtcaac ctcgtaggtc
    16081 cgcccagggg gcctcattct gcttcttgct gcgggcgcgc tcggcgccac cgcgctgccg
    16141 gtgccagggc aggaactgcg gcaacggtgt catcgcgtgc ccgcccattg atggcagccg
    16201 gtcccgcctg cgggggcctc cctcgtgatt gcagctgcac cggacgggac ggcacagtgc
    16261 cggcccaggg gagcgggtgc acaaagccct gttcaccgga gtgggagtca gcaccgggcc
    16321 aatggtccgg cgcgtgctgg tcgggcccgg acgacctggc tacgacgtgg accttcggga
    16381 agtggacggg acctcccgct gacggacctg ccatgtcttg atgggcatgc ggcctgggac
    16441 tgggaggaca acgatgaagg cgtacaccgt ccatcacagg aaggaatcgg ggccatgact
    16501 gatcggggaa acgggtacgt gattcccgaa ccggaggagg agcccgactt cgcggacgag
    16561 cactctcgcc ccacctatgc cgatgagccc tcgacggagg atcccgacga gtcggttccc
    16621 tcgggggagg gcggagacgg gggaatggac cccacctgaa aggtccttcg gccaggtgaa
    16681 gccgcagcgt cgtcggcacc cgggcccacg gggcgcgggc cgacggatat gccctggaag
    16741 gcccatgaat atcttggtga gaggccgtcc ggccattggg ccgggcggcc cggcggtcat
    16801 gccctggccg gggcggaccc acggcaggaa caccgtcaag cgcgccctgc tgccgctgaa
    16861 ggagatcttc gccatacgcc aacgacgact cacgcggctc caccctgccg aatcggtaca
    16921 ggaaccgctc atgcggctgc agttcagcaa gcccgccgac cacgcccggg cattcgcccg
    16981 caacctctcc cacccgatac ccggcagaac gatccgactg cccaccgtca cgcaccggtg
    17041 cagtactagg atttcggccg tctgcgcggc tggctgcgcc gcccggatcg cgtcccgcat
    17101 cgtccgccgc ggcaccgaac ctcccaaccg actgggccgg catcgcaggg tcgtggaacg
    17161 caccgtcgtg actcaacgga tgcccgccgt ctgcaccgcc gatacgagcg caaggccgcg
    17221 tacttcctcg acttcgtcga ctcggtcacc gggtagctca tggacgcgac gcttgcgctt
    17281 tcgttcggcc cgcggaaccg ggcacgtgcg gcaggctgcc tgcgggccgc tcctgcacac
    17341 gggcgaggcc cctgcgtgcg gtgaaacccg caggcagggg gcttgtttgg ggtcccgccc
    17401 gtgcggcgcg cacgatcccg gtgagtgtgc tgcactggaa tcaggaggtg catcgtgtcc
    17461 ggtcgtgcag ggaaacccag gaacatcctt cttgtgtggc tgatctggcc gctgatcacg
    17521 ctgggcgtct accacttcgt ctggtattac aaggtgaatc gcgaggcccg tgacttcgat
    17581 ccgcggatcg aagtcaatcc ggcgtatgcc gtcctggcca tcctcatcgg ctggctggtg
    17641 atcgttcctc ccttcgtgtc ggtctacaac accggtcagc gcattgccga gatgcagaag
    17701 tcggccggga tgcagcccag ttgcaatccc tggatcgggc tgatcctcat gatcatcgcc
    17761 ggcctgcacg cgctctacta ccagcacgag ctgaaccaga tctggaccca ctaccggaac
    17821 ccggccgagg ggcaacaggt gcctctcgct gtctgatgcc cgggatccgt ggcttcgtgc
    17881 gaagcgggag ccggtgcagc gtgggcccct gtccggtggg cgaattccag tggtcgtatc
    17941 gcaacgcgtg atcaccgccg tgtggcggtg agcagtttgg acagacgctc ggctggggtt
    18001 tccccgtcgg gcgtcttgcg tgggcggctg ttgagttcgg cggcggcgtc caggtcctgg
    18061 cggctgtaac gcgacgcgct ggtgcctggg gggactggcg cagcgggccg ctcgtgttct
    18121 cgttcggccc ggtccgcact gccatgggca ggcaggatta cagaagtggg ccgcgtgttc
    18181 gtggcggtgg agaagaggtg gtgacttgcc ggctcgttgc cctgatccca ggtcagtgac
    18241 cgccgtaggt gggccagaag ttcgctgatg gtggcggtga aagccagcgg gtgcaggtcg
    18301 tcgcctgtgc ggggtacaag acgcacaggt ggccgtgccg gcccggtgtc cgggcagacg
    18361 tcgcgaggct gacgcccccg cccccgggcg ccggtgcgtg acgaacacgg cctcgagagt
    18421 gcggcccttg agcagtcggg gcaggagccg ccggtgccgg cgtcccagta gacggtttcc
    18481 agcacgaagt cctcacgcgc accctgtccc ggcggcgggc cctggtccgg acgtccttga
    18541 cccaggccgg gcagcggggg agttattgtc aagacctgtg ggtcggcggc gtctggtgca
    18601 ttggccagtc atcaagaatc gaccagggga tcggggcagt cgcgcatgtc cagtggtagc
    18661 gatccacggc ctcgatggat cacaaggctc gtggaagagt tgagcgagtt tctgcaagag
    18721 ccggtgatac tcgtggagtc actcaaagag tgcctggtcg atgacgacgc tttctcctgc
    18781 ctcatccgca gttcaccccc gcagggccga gctttccagc tcagctggga gggaatcctc
    18841 gggatggagc ccatcgacgg gaagccccac gccagtgttt cgctgtttct gtacagcagg
    18901 aaccgccggc tcgccctgtc cggccatgcc gagggaagtg tcctggaaat cgtgtatgaa
    18961 ggctcgctgg agcatggtgg gcgatgggcg aacccctgtt gggatcagga tgagttcggc
    19021 gaatacctca cgttcgagac atacggcgag tgctgagctg acggcgatga tctgtacggg
    19081 gtgcaggaag cggagcggcg agctgtcccg gactcgtgct cccgcgaccg gaccctgacg
    19141 gggtttggag ggcaccactg ctgtgacgcc tgcgggagta gcacggcatc ggtgagtaat
    19201 cgatgctctg cccgggctgg agttctgctt acagactgag cggatgtttc ctacgccgaa
    19261 gtgccctgat tccgattgcc cacgcgcgtg gagcactttc ggagacggat cgcagcattt
    19321 gggggagtgc gcatcgatcg acggggcact ggcggatccg gggtttctgg tgcgggccga
    19381 tccggggcgg gtggaggctc tgctggaggg cgttgtggtc ccggagtcgt gctgggtggc
    19441 atcggtgtac cggatgtcgg ccgggcggca ccgggatgtc actgcggggg tgcggcggca
    19501 ggtgctcgcg ctggacgccg cgcgtctggg aagccggcgt ctgtgccata gcatctccgc
    19561 agtggaggtg gacggcgagc cgacggagcg gtggcaggtg gcctgggccg cctccacggc
    19621 tgggcgcccc ttccggcacg agctcgtcaa cgggcccggg aacacctcga tagccacggc
    19681 gctggtcgac ggccgccccg ttgccgtcac actcggcgac tacaagaacc gctggaccaa
    19741 caccctgcgg gtgtgggacc tggtcaccgg cggacaggtg ggagaagtcc ggtgcactcc
    19801 gccggcggac aaggtgttgg gcaccgcggt ggtcgagggc cgtccggtcg cgttcacttg
    19861 ggttcggcag aacacggccg tgcgcatgtg ggacctgagt gctcaggccc tggtcggcga
    19921 gttccccctg ggacagcgct gggtttccgg atggacgacg atcacgctgg acggccggca
    19981 ggttgctctc accggtgggg atgacccgac ggtccgcgca tgggacctgg tgaccggcag
    20041 gcagaaccgt gagctcgtcc tgaccggtca tgccggcagc gtgtcagtgc gggccacggc
    20101 ggtactcgac agacgccccg tcgtcgtggc atccgcagac caggtggtcc gggtgtggga
    20161 tctgcgcacc ggcgaaccgg taggtgggcc catcgacacg gataccgaag gcgctttcgc
    20221 actcgtgggc tgtgcaacgg cgaaagtcga cggccgcgcg gtcgcggtga ccgccaacgc
    20281 ccgttccctg cgggtgtggg acctggccac cggggagccg gttggcgaac cgcttctgga
    20341 ccccgggcaa ctcaacgggt ttctcacggg cgtgaccacc acgactctgc aaggtcatcc
    20401 ggtcgctgtg acagtctcca ccgatcaggg cggcatgctc gaggtgtggg acctggccag
    20461 cggcgaacgg atcggttcac ccgacgacgg ctacgacgac gtcgggctgg aaagcgtcgc
    20521 cacgaccgtg gtgggcggtc gcccggtggc agtcacctgc tgtcgcaggg gacgggtacg
    20581 ggtgtgggac ctggtctatg gcaaaccgct cggtgaaccc cgcactggcc acaacgccac
    20641 ggtggacgcg gtggcgaccg gggtggccga cggccgtccg gtcgccgtca cggcaagcag
    20701 cggcgatggg acggtccggg tatgggacct ggtcggcggg aagccggtcg gcgaaccctt
    20761 cggcggcctt accggttcgg gtgtctgggc gctggccact gccgtggtgg acgggcgttc
    20821 ggtcctggtc gccggcagcg gtgacgggag catgttcatc tgggacctga cgaccggtga
    20881 gccggtcggt gagccgatga ccggacacag tgcctgtgtt tctgcagtgg cgacaacagt
    20941 ggtccgggaa cgaccggtcg ccgtcaccgg aagttgggac accacgctac aggtatggga
    21001 tttgtcgacg agggagc
//
