LOCUS       NZ_BMWB01000011        13038 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces xantholiticus strain JCM 4863 sequence11, whole genome
            shotgun sequence.
ACCESSION   NZ_BMWB01000011
VERSION     NZ_BMWB01000011.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces xantholiticus
  ORGANISM  Streptomyces xantholiticus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 206028)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 114X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014651015.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:24:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,091
            CDSs (total)                      :: 7,016
            Genes (coding)                    :: 6,693
            CDSs (with protein)               :: 6,693
            Genes (RNA)                       :: 75
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 323
            CDSs (without protein)            :: 323
            Pseudo Genes (ambiguous residues) :: 0 of 323
            Pseudo Genes (frameshifted)       :: 187 of 323
            Pseudo Genes (incomplete)         :: 270 of 323
            Pseudo Genes (internal stop)      :: 13 of 323
            Pseudo Genes (multiple problems)  :: 140 of 323
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:39:19
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 88749
            Orig. end                         :: 101787
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMWB01000011.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..13038
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="1"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..13038
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..13038
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:8038](-)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..8038)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     gene            complement(777..1502)
                     /locus_tag="IE198_RS18275"
                     /old_locus_tag="GCM10010381_36940"
     CDS             complement(777..1502)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005309271.1"
                     /locus_tag="IE198_RS18275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_36940"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_189888007.1"
                     /transl_table=11
                     /translation="MGHLKQRNLITARERLRDQVAHALRAALISGELRPGEVYSAPGLA
                     EDFGISATPVREAMLDLAREGLVEPVRNKGFRVTEVNERDLDQYTEIRTLIEVPMVGRI
                     TRSASVEDLQALRPVAEEIVRAACDHDLIGYLEADRQFHLSLLALAGNDRLVETVGDLR
                     KRSRLYGLTALDERDQLIPSAEEHIELLDLMVAGDAKGAEKCMARHLGHVRSLWAEGAQ
                     EKEGRPAGRATGRRLGATR"
     misc_feature    complement(1535..1549)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.18"
                     /tool="antismash"
     misc_feature    1556..1566
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 20.42"
                     /tool="antismash"
     misc_feature    1562..1577
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.3"
                     /tool="antismash"
     gene            complement(1595..2974)
                     /locus_tag="IE198_RS18280"
                     /old_locus_tag="GCM10010381_36950"
     CDS             complement(1595..2974)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091454.1"
                     /locus_tag="IE198_RS18280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_36950"
                     /product="aldehyde dehydrogenase"
                     /protein_id="WP_189887781.1"
                     /sec_met_domain="Aldedh (E-value: 5.2e-119, bitscore:
                     391.3, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTSQVVSHNPTDPSDVLVRLPAPGAFAAVSAVERARTARPDWF
                     TGGAAARSAALGAVAAAVEAAGEELAALAVREVGKPVAEARAEVARTAAIWRYYAQTPF
                     DPVGAVHETADGAGLLLTRRRPRGVAGVITPWNFPFAIPSWKAAPALAAGNTVVLKPAP
                     EATACAERLAEIVCRMVPDGVFTVLPGGPTEGNAVVSAVDVVSFTGSTRTGGAVVRTAT
                     TRGIPVQAEMGGLNAAIVLPDSDIARAAAHIAAAIAGYAGQKCTATSRVIAVGAALDPL
                     REALTEALRAVPVGDPSDPATVCGPLIDGRARDAVLRAREGLAELAGATAPEGTDGWYA
                     APALVEKVPHGHRLLREEVFGPLAALLPADDLAHAVRITNSVPYGLVTSVHTASLDATL
                     HGLDGLDTGLVRVNAPSTGVDFHLPFGGTKASSHGPREQGRAALEFYTSGRTYTLVPAD
                     R"
     gene            complement(2971..3975)
                     /locus_tag="IE198_RS18285"
                     /old_locus_tag="GCM10010381_36960"
     CDS             complement(2971..3975)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891275.1"
                     /locus_tag="IE198_RS18285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_36960"
                     /product="proline racemase family protein"
                     /protein_id="WP_189887783.1"
                     /transl_table=11
                     /translation="MRTRHVFHAVDSHTEGMPTRVITGGVGVVPGATMAERRLHFIEHL
                     DHLRTLLMYEPRGHASMSGAILQPPTRPDADYGVLYIEVSGLLPMCGHGTIGVATVLVE
                     TGMVPVTEPVTTVRLDTPAGLVSVDVRVEDGAAEAVTLTNVPAFCAGLDRKVDVPGHGT
                     VRYDLAFGGNFYAFVELDALGLPFDRSRKGELLTAGLAVMDAINASPDRPVHPEQPEIA
                     GVKHVYLAAPGSDAHRSRHAMAIHPGWFDRSPCGTGTSARMAQLHARGALPLHRDFVNE
                     SFIGTEFTGRLVAESEVGGVPAVVPRITGRAWITGTAQYFLDPDDPFPGGFLL"
     gene            complement(4008..4928)
                     /locus_tag="IE198_RS18290"
                     /old_locus_tag="GCM10010381_36970"
     CDS             complement(4008..4928)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005309273.1"
                     /locus_tag="IE198_RS18290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_36970"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_189887785.1"
                     /transl_table=11
                     /translation="MTATKATATWTTDRPWRGIMVATALPLREDLSVDLDAYAEHVRGL
                     IDQGCDGVVPNGSLGEYQSLTDDERARVVRTAVAAAGDGARVMPGVAAYGSAESRRWAE
                     QAAEEGCGSVLLLPPNAYRADEPAVRAHFVEVARAGLPVVGYNNPIDTKVDLTPDLLAR
                     LHGDGSIVAVKEFSGDVRRAYEIGELAPDLDLLVGADDVLLELSLAGAVGWIAGCPNAF
                     PATCAELYHAAVAGDLDTALPLYKALHPLLRWDSRTEFVQAIKLSMDLVGRRGGPTRPP
                     RVPLSAKDAATVRAATGKAVADGHH"
     gene            complement(5001..6548)
                     /locus_tag="IE198_RS18295"
                     /old_locus_tag="GCM10010381_36980"
     CDS             complement(5001..6548)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018514376.1"
                     /locus_tag="IE198_RS18295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_36980"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_189887787.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 4.7e-26, bitscore:
                     85.3, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 1.7e-13, bitscore:
                     44.4, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPNSPSDRAADDPYGAVHDLVVIGAGCAGLAGAVTAFEQGLSVAL
                     LDTAGRIGGQFYRHPAPAIGAVRPEALHHDWSAFAGLRHRLEASDVVHLAGHHVWTVAR
                     QDGANPRWTVHAVTGVDGDGERPVRVHARAVLLATGAYERQLPFPGWTLPGVVGAAGAQ
                     AMLKSGLVLPGRRVVVAGSGPLLLAVASSLAAAGARVPLVVEASGYLGYARRPDVLAVN
                     PQKLAEAVVHGAALLRHGVRLRTRSAVTDVHGADRVEAVTVSRLDRDWRPVQGSGRRIA
                     CDALAVGHGLVPQTELATSLGCATRRTQDGTYALALDALQQTSVPGLWAAGETGGIGGA
                     QLARVEGELAGFAVAAQVRGGHEPARDGRVRELQRRRERMRAFAGAMTAMHAPGPGWVD
                     WLDDATEVCRCEEVRAGAIREAVDEHGARDARTVKLLTRAGMGWCQGRVCGAAVARLAA
                     GGGAPAVPPSPERRPLAVPVALELLGSLDTTAPTSSPAAPAQRPDTAGPDGAATSGD"
     gene            complement(6529..6852)
                     /locus_tag="IE198_RS18300"
                     /old_locus_tag="GCM10010381_36990"
     CDS             complement(6529..6852)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005309276.1"
                     /locus_tag="IE198_RS18300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_36990"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_189887789.1"
                     /sec_met_domain="Fer2_4 (E-value: 1.8e-26, bitscore: 85.7,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARDRTPAELVGAAPEQPPFDITFDGRAITALPGQSVAAALWSAG
                     VLAWRTTRRGGRPRGAFCGIGQCYDCLATINGRPNRRACLVPARPGDTITTQEGHGHAE
                     LAV"
     gene            complement(6842..8038)
                     /locus_tag="IE198_RS18305"
                     /old_locus_tag="GCM10010381_37000"
     CDS             complement(6842..8038)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005309277.1"
                     /locus_tag="IE198_RS18305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_37000"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_189887791.1"
                     /sec_met_domain="DAO (E-value: 2.3e-66, bitscore: 218.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTRNSPDLVVVGAGVVGAACAYYAARSGLSVTVIDRGAVAGGTT
                     GAGEGNLLVSDKEPGPELELALLSTRLWRELADVLPPRIEYEAKGGLVVASGEASLAVL
                     RDFAARQERAGVRVRQIGSGRLRDLEPHLAEDLAGGFHYPQDAQVQPALAAAHLLRAVG
                     GHGPGRVFLRLGEEVTGILKGASGEVRGVRTASGDLHAPYVVNAAGTWGGRLARLAGVD
                     LPVLPRRGFVLVTEPLPRVVRHKVYTADYVADVASGSAALQTSAVVEGTPAGPVLIGAS
                     RERVGFDRALSVEALRRLAAQATRLFPVLAGVHAIRTYAGFRPYLPDHLPAIGSDPRVP
                     GLLHACGHEGAGIGLAPATGTIVARIVSGAGLPMDITPFGPDRFEGTSQPRKEPRHGA"
     misc_feature    complement(8042..8057)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.3"
                     /tool="antismash"
     misc_feature    complement(8050..8060)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     gene            complement(8127..9500)
                     /locus_tag="IE198_RS18310"
                     /old_locus_tag="GCM10010381_37010"
     CDS             complement(8127..9500)
                     /EC_number="3.4.11.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072439.1"
                     /locus_tag="IE198_RS18310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_37010"
                     /product="aminopeptidase P family protein"
                     /protein_id="WP_189887793.1"
                     /transl_table=11
                     /translation="MKETAASAHRTVSHDLPLSPEFEAFMAGGWAPSPLAGDVRLPVAG
                     LTPSRRARLSARFPGERLIVPAGELSVRSNDCDHRFRPHSAYAWLTGLTGEEQAGHVLV
                     MEPDGLHGHEAVLYVRPRSPRTDAGFHRDRRYGEFWVGRRPDLAEAEHLTGIRCADLEG
                     RGTLPPGRDALVDAELASALSELRLVKDAWEVEQLQLAVDHTAAGFEDVVRSLPRALAH
                     PRGERWIEGVFGLRARAEGNGTGYETIAAAGAHACVLHWIRNDGPLDPRQLLLLDAGVE
                     TDSLYTADITRTLPLSGRFSPVQRQVYELVLAAQEAGIAALRPGARFRDFHGAAMRLIA
                     EGLTEWGVLGSPEGEFHRRYTLCSSGHMLGLDVHDCAQARATAYLDGVLEEGQVLTVEP
                     GLYLQPDDETLPVELRGIGVRIEDDLVITAEGARLMSGALPRTPDAIEAWMGALAEGH"
     misc_feature    9532..9550
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.69"
                     /tool="antismash"
     misc_feature    9533..9549
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.07"
                     /tool="antismash"
     misc_feature    9537..9547
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     gene            9612..11360
                     /locus_tag="IE198_RS18315"
                     /old_locus_tag="GCM10010381_37020"
     CDS             9612..11360
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891270.1"
                     /locus_tag="IE198_RS18315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_37020"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_189887794.1"
                     /transl_table=11
                     /translation="MNKRTRTALAAALVTTLALGAAGCFGGTRSTDGKGRGTNPALANQ
                     GAAIGGTPTKGGTLTVLSNQDFTHLDPARNWVMGDMDFGTRLLYRTLVTYRAEPGAGGG
                     ELTPDLAADLGTSSNGARTWTFRLKKGLKYEDGSPVTAHDIKYNVERSFSPDLPGGPDY
                     AARYLAGAEGYQGPATGKHLDSVKVPDDHTIVFELRKPFAEFPYATVLPTFAPVPKARD
                     KGPRYDNRPFSSGPYRIERYARDKQLVLVRNPHWDPGSDTVRKAYPDRIVVTMGLKGNQ
                     IDDRLIASSGADSSAVPWGKLRPESASKVLTRPDVRARLLAESTNCTEMVQMHTGRAPF
                     DHVKVRQAVQYALDREAVLTASGGPALGDPATALMPGSLFGGRQPDTLKIPLAGDVAKA
                     RQLLKEAGRPDGFATSITVSSGDKGVGEAIQQSLGRAGIKVTIETVDPSAFYDTIGDTE
                     NRTDLVYTGWCPDYPSGSTFLPFVFDGRYIKEKGNSGNHSLFRDRVTMKRMDEIAAMTD
                     ARQAAKAWQDLDGRILAEAPTAPAVIERMPLLLGTNIAGAFGHTSFGGQIDYATVGLKD
                     PAKSGR"
     gene            11375..12304
                     /locus_tag="IE198_RS18320"
                     /old_locus_tag="GCM10010381_37030"
     CDS             11375..12304
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017237881.1"
                     /locus_tag="IE198_RS18320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_37030"
                     /product="ABC transporter permease"
                     /protein_id="WP_189887795.1"
                     /transl_table=11
                     /translation="MAATTSPAVPAGRGPWQLARAELRRRTSVKLSLAVVALFVFMAAA
                     APLLSSLSGWGPDEFDKSAVDPYLGGQPIGPLGGVSAEHWLGVEPVTGRDLFARVVHGA
                     QVSLLIAFAATAIVVVTGVAAGTAAGYFGGGTDAVLSRLMDLTMSFPSLIFMIAMMSVA
                     RDVNRIVLMTAVIGLFGWPGIARVVRGQTLSLKHREYVDAARVGGAGPWRILTRDILPG
                     VAGPVIAYTTLIVPGMIATEAALSYLGVGVRPPTASWGQMIAESVSFYDTDPMYFIVPS
                     TCLFLTVLAFTLLGDALRDILDPRSARA"
     misc_feature    complement(12786..12800)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
ORIGIN
        1 tcgccgactt caccgggaac gccaccgagg ccgaccggct cgaacgcgcc atcctccggc
       61 tcgaccccac ccaccgcgcc gccctggagg ctcagacaag gaaggccgcc ggcgcgcccg
      121 gcgtcaaggc ccctcgggcc gccgacctgt acgccgccgg gctcgccgcc gcaccggact
      181 ccgccgcgat gcaggacggc ctcgaccggg ccacgtaccg catgctgcgc ggcatgcgct
      241 ggctcgccct gctcggtgtc ggcctcgcag gagcgatgat ggacctgtac atcgaagagg
      301 gcgaggtgcc aagcgagttg ccgctcccgc tcggtcagcg cctctggtac ctcgtaccga
      361 tgacggccat ctggatcgtc ggcgccctgc tccgccaccg ccggcgtcgc accggtgtcc
      421 ggctcaacgt ccggtcactg ctgcgccgcg ccgtatgggc ccgcatcgtg atcgcccagg
      481 cggcctgggc gatgctgtgc gcgctgctga tcgccgaggt cccgtggacg gacaggctcc
      541 tgccgcaggt gctgttctgg gccgggctcg tgcccacact cgccacaatc tggttcgacc
      601 gcccgaaggc gggatgagcg aaagccacgc ggtcgatcga ggacggctgc caccatgact
      661 tcccggagtc gcaccacctc ctcgaagcgg ggacgccgga gcccgggtcg gacatgccgt
      721 ccgccggcgc tgtgcgcgcg atgtcccgca cggggcccgg cgcatcgcga ccgggctcag
      781 cgggtcgcgc ccagcctccg tccggtggcg cggccggcgg gccggccctc cttctcctgc
      841 gcaccctcgg cccagagcga gcgcacatgt cccaggtggc gggccatgca cttctccgca
      901 cccttcgcgt cacccgccac catcaggtcg agcagctcga tgtgctcctc ggccgacggg
      961 atcagctggt cacgttcgtc cagggcggtc agtccgtaca gccgcgagcg cttgcgcaga
     1021 tcgccgacgg tctcgacgag ccggtcgttg ccggcgagtg cgagcaggga gagatggaac
     1081 tgccggtcgg cctcgagata gccgatgagg tcgtgatcgc acgcggcgcg cacgatctcc
     1141 tcggccaccg gccgcagcgc ctgaaggtcc tcgacggagg cgctgcgggt gatccggccg
     1201 accatgggga cctcgatcag ggtgcggatc tcggtgtact ggtcgagatc gcgttcattg
     1261 acctcggtga cacggaagcc cttgttgcgg accggctcga cgaggccctc gcgggccagg
     1321 tcgagcatcg cctcccgcac cggtgtcgcg gagatcccga agtcctcggc gaggccgggc
     1381 gccgagtaga cctcgccggg gcgcagttcc ccggagatga gcgcggcgcg cagggcgtgg
     1441 gcgacctggt cgcgcagccg ctccctggcg gtgatgaggt tgcgctgctt caggtggccc
     1501 atgccggtcg tgttcccttc gccctgtgcc ctcgtggccg agagagtcac cagcgtacaa
     1561 tgtcacgttg ttttcgcagg tgcccacggg ggagctaccg gtcggccggc accagggtgt
     1621 aggtccggcc ggaggtgtag aactccaggg cggcccgtcc ctgctcccgc ggtccgtggc
     1681 tggatgcttt cgttccgccg aagggcagat ggaagtcgac gccggtggaa ggcgcgttga
     1741 cgcgcaccag gccggtgtcg agaccgtcga gcccgtgcag tgtcgcatcg agcgaggcgg
     1801 tgtgcacgga ggtgaccagg ccgtacggaa cggagttggt gatccgtacc gcgtgggcca
     1861 ggtcgtcggc gggcagcagg gccgccagcg gtccgaagac ctcctcgcgc agcagccggt
     1921 gaccgtgcgg caccttctcg accagtgcag gcgccgcgta ccagccgtcc gtcccctcgg
     1981 gggcagtggc gcccgcgagt tcggcgaggc cctcccgcgc gcggagcacc gcgtcgcggg
     2041 cccgcccgtc gatgagtggt ccgcataccg tggcgggatc ggagggatcg cccacgggga
     2101 ccgcgcgcag cgcctcggtg agggcctcgc gcagcggatc gagggcggcg ccgaccgcga
     2161 tcacacggct ggttgccgtg cacttctgtc ccgcgtaccc ggcgatcgcg gcggcgatgt
     2221 gcgccgcggc ccgggcgatg tcggagtcgg ggaggacgat cgccgcgttc aggccgccca
     2281 tctcggcctg caccggaatg ccgcgcgtgg tggcggtacg gaccaccgca ccgcccgtcc
     2341 tcgtggaccc ggtgaaggag acgacgtcga cggcggagac gaccgcgttg ccctcggtgg
     2401 gcccgcccgg cagcacggtg aacactccgt ccggcaccat ccggcagacg atctcggcca
     2461 ggcgctcggc gcatgcggtc gcttcgggtg ccggcttgag cacgacggtg ttgccggccg
     2521 cgagcgccgg ggccgccttc cagctgggga tggcgaaggg gaagttccac ggggtgatga
     2581 cgcccgcgac tccgcgcggg cggcggcggg tgagcagtag ccccgcaccg tcggccgtct
     2641 cgtgaacggc gccgacgggg tcgaaggggg tctgggcgta gtaccgccag atcgcggcgg
     2701 tgcgggccac ttcggcgcgt gcctctgcga ccggcttgcc cacctctcgt acggcgaggg
     2761 ctgccagctc ctccccggcg gcctcgacgg cggcggcgac cgcgccgagc gccgccgagc
     2821 gggcggcggc cccgcccgtg aaccagtcgg gccgggcggt gcgggcccgc tccacggcgg
     2881 agacggcggc gaaggcaccc ggggcgggca gccgcacgag aacgtcggaa gggtcggtcg
     2941 ggttgtgcga cacgacctgg ctggtggtgg tcacaggagg aaacctccgg ggaacgggtc
     3001 gtccgggtcg aggaagtact gggcggtgcc ggtgatccag gcgcgcccgg tgatacgggg
     3061 gacgacggcg ggcaccccgc cgacctcact ctccgccacc agacggccgg tgaactcggt
     3121 cccgatgaag gactcgttga cgaagtcgcg gtgcagcggc agggctccgc gggcgtgcag
     3181 ctgcgccatc cgcgcggagg tgccggtgcc gcacggcgag cggtcgaacc agcccgggtg
     3241 gatggccatg gcatggcgtg agcggtgcgc gtcagagccc ggggcggcga gatagacgtg
     3301 tttgaccccg gcgatctcgg gctgctccgg gtggaccggg cggtccgggg acgcgttgat
     3361 cgcgtccatg acggcgagcc cggccgtgag cagctcgccc ttgcgggacc ggtcgaacgg
     3421 cagccccagc gcgtccagtt cgacgaacgc gtagaagttg cccccgaagg cgaggtcgta
     3481 cctcaccgtc ccgtgcccgg gcacgtccac cttgcggtcc aggccggcgc agaacgcggg
     3541 gacgttggtg agcgtgaccg cctcggccgc gccgtcctcg acccgcacgt cgacggagac
     3601 gagcccggcc ggggtgtcga ggcggacggt ggtgacgggc tcggtgaccg gaaccatgcc
     3661 ggtctcgacg aggacggtgg ccacgccgat ggtgccgtgt ccgcacatcg gcagcaggcc
     3721 ggagacctcg atgtacagga ctccgtagtc ggcgtcgggg cgggtcggcg gctgaaggat
     3781 cgcgccgctc atggaggcgt ggccgcgcgg ctcgtacatc aggagcgtgc gcagatggtc
     3841 gaggtgctcg atgaagtgga gcctgcgctc ggccatcgtg gcgccgggga ccaccccgac
     3901 gcctccggtg atcacacgcg tgggcatgcc ctcggtgtgc gagtcgacgg cgtggaagac
     3961 atgacgggtc cgcacgaatg tcccttcctg cgagggcgga tcgggggtca gtggtggccg
     4021 tcggcgacgg ccttcccggt cgccgcgcgc accgtggcgg cgtccttcgc ggacagcggc
     4081 acacgaggcg ggcgagtggg gccgccgcgg cggcccacga ggtccatgga caacttgatg
     4141 gcctgcacga actcggtcct ggagtcccag cggagcagcg gatgcaatgc cttgtagagg
     4201 ggcagtgcgg tgtcgaggtc cccggcgacg gcggcgtggt agagctcggc gcaggtcgcg
     4261 ggaaaggcgt tcggacagcc ggcgatccag ccgacggcgc ccgcgaggga gagctcgagc
     4321 agaacgtcgt ccgcgccgac cagcagatcg aggtccggag cgagttcgcc gatctcgtag
     4381 gcccggcgca catcaccgct gaactccttg acggccacga tgctgccgtc gccatggagc
     4441 cgggccagca gatcgggggt gaggtcgacc ttggtgtcga tggggttgtt gtagcccacg
     4501 acgggcagtc ccgcgcgggc gacctccacg aagtgggcgc gtaccgccgg ctcgtcggcg
     4561 cgataggcat tgggcggcag cagcaggacg cttccgcagc cttcctcggc ggcctgttcc
     4621 gcccagcggc gtgactcagc gctgccgtag gcggcgaccc cgggcatcac gcgggctccg
     4681 tcgcccgcgg ctgcgacggc ggtgcggacc acgcgggccc gctcgtcgtc ggtgaggctc
     4741 tggtactcgc cgagtgagcc gttgggcacg acgccgtcgc agccctggtc gatgagcccg
     4801 cggacgtgct cggcgtaggc gtcgaggtcg acggacaggt cctcgcgcag ggggagcgcc
     4861 gtggcgacca tgatgccgcg ccaggggcgg tcggtggtcc aggtggcggt ggccttggtg
     4921 gcggtcatta caggacctct tccatagggt gtgacatttg actaagcgtt gtacgacacc
     4981 cacaaggggg cgcccggacc tcagtcgccg gaggtggcgg ctccgtccgg gcctgcggtg
     5041 tcgggccgtt gggccggggc ggcgggcgag gatgtcggcg cggtcgtgtc gagggagccg
     5101 agcaactcca gcgcgacggg cacggcgagc ggccgccgtt cgggagaggg cggcacggcc
     5161 ggggcgcccc ctcccgccgc gaggcgggcc acggccgccc cgcacacccg gccctggcac
     5221 cagcccatgc ccgcacgggt gagcagcttg acggtgcggg cgtcacgggc cccgtgctcg
     5281 tccaccgcct cacggatggc gcctgcccgt acctcctcgc agcggcacac ttccgtcgcg
     5341 tcgtccagcc agtcgaccca gcccggcccc ggcgcgtgca tggcggtcat cgcgccggcg
     5401 aaggcccgca tgcgctcgcg ccgccgctga agctcccgca cccgcccgtc gcgggccggt
     5461 tcgtgccctc cgcgcacctg ggcggccacc gcgaaccccg caagctcccc ttccacgcgg
     5521 gcgagttgcg cgcccccgat gccaccggtc tcacccgccg cccacaggcc cggcaccgag
     5581 gtctgctgca gtgcgtccag cgcgagggca tacgtcccgt cctgcgtacg ccgcgtcgca
     5641 cacccgaggc tcgtggccag ctcggtctgg gggaccagac cgtgccccac cgcgagcgcg
     5701 tcgcaggcga tccggcggcc cgacccctgt acgggccgcc agtcgcggtc gagccgggag
     5761 acggtgaccg cctccacccg gtcggcgccg tggacatcgg tcaccgcact gcgggtgcgc
     5821 aaccgtacgc cgtgccgcag cagcgcggcg ccgtggacca cggcctcggc cagcttctgc
     5881 gggttgacgg cgagtacgtc cgggcgacgt gcgtacccga gatagccgga tgcctccacc
     5941 accaggggaa cgcgcgcccc ggcggcggcg agcgaggagg cgacggcgag cagcagcggg
     6001 ccgctgcccg ccacgacgac gcgcctgccg ggcaggacga gccccgactt cagcatcgcc
     6061 tgcgctcctg cggcgcccac gactcccggc agcgtccagc cggggaaggg cagttggcgt
     6121 tcgtaggcgc cggtcgccag caggacggcg cgggcatgta cgcgcaccgg gcgctcgccg
     6181 tcgccgtcca ccccggtgac cgcgtgcacc gtccagcgcg ggttcgcccc gtcctgccgt
     6241 gccacggtcc agacgtggtg cccggcgaga tggacgacgt cgctcgcctc gaggcggtgg
     6301 cgcagaccgg cgaaggcgga ccagtcgtgg tgcagggcct ccgggcgcac ggcgccgatg
     6361 gccggggcgg ggtggcggta gaactggccg ccgatccggc cggccgtgtc cagcagggcg
     6421 accgagagcc cctgttcgaa ggcggtgacg gcgcctgcca ggcccgcaca gcccgcgccg
     6481 atcaccacga ggtcgtgcac cgcgccgtac gggtcgtcgg cggcacggtc agacggcgag
     6541 ttcggcatgg ccgtgtcctt cctgagtggt gatcgtgtct ccgggacggg cgggcaccag
     6601 acaggcccgc ctgttgggcc ggccgttgat cgtggcgagg cagtcgtagc actggccgat
     6661 gccacagaac gctccgcgcg gacggccgcc tcggcgcgtg gtgcgccagg cgaggacccc
     6721 ggccgaccac agggcggcgg cgacggactg cccgggcagc gcggtgatcg cccgcccgtc
     6781 gaaggtgatg tcgaacgggg gctgttcggg tgccgcgccg acgagttcgg cgggggtgcg
     6841 gtcacgcgcc atggcgcggc tccttccgcg gttgcgaggt cccctcgaac cggtcgggtc
     6901 cgaacggagt gatgtccatg gggagcccgg ccccggacac gatccgggcg acgatggtcc
     6961 ctgtggccgg ggcgagcccg atccccgcgc cttcgtgccc gcaggcgtgc agcaggccgg
     7021 gtacgcgcgg gtcggatccg atcgcgggca gatggtcggg caggtagggg cggaatccgg
     7081 cgtacgtccg tatcgcgtgc accccggcga gtaccgggaa caggcgggtc gcctgggccg
     7141 cgaggcggcg cagcgcctcc accgacaggg cgcggtcgaa gccgacgcgt tcccggctcg
     7201 cgccgatcag gaccggcccg gccggggtgc cctcgacgac ggcggaggtc tggagcgccg
     7261 ccgagccact ggcgacatcg gcgacgtagt cggccgtgta gaccttgtgc cgcaccacgc
     7321 gcggcagcgg ctcggtgacc aggacgaagc cccgacgggg gagcaccggc aggtccactc
     7381 ccgcgagccg ggccagccgg ccgccccagg tcccggcggc gttcaccaca tacggagcgt
     7441 gcagatcacc gctcgccgtc cgtacgcccc gtacctcgcc gctcgccccc ttgaggatgc
     7501 cggtgacctc ctcgcccagc cgcaggaaga cccggccggg gccgtgcccg cccacggcgc
     7561 gcagcagatg tgccgcggcg agcgcgggct gcacctgggc gtcctgcggg tagtggaagc
     7621 cgcccgccag gtcctcggcc agatggggct ccaggtcgcg gagccggccg ctcccgatct
     7681 gccggaccct cacgcccgcc cgctcctggc gggccgcgaa gtcccgcagg accgccaggg
     7741 acgcctcgcc ggaggcgacc accaggccgc ccttggcctc gtactcgata cggggcggca
     7801 gcacgtcggc cagttcgcgc cacaaccggg tggacagcag agcgagttcg agctcggggc
     7861 ccggctcctt gtcggagacc agcaggttgc cctctccggc tcccgtggtc ccgcccgcga
     7921 cggcgccgcg gtcgatcacg gtgacggaga ggccggagcg tgcggcgtag taggcgcagg
     7981 cggcgccgac cacgcccgct ccgacgacga cgagatccgg ggagttcctc gtgagcacgt
     8041 cagtaatatt tcacattgca ctgccacgtg ccaagaggca ggccaccaag aggcgctccg
     8101 agcccggggc gggctcgacc ccttgatcag tgcccctcgg ccagcgcccc catccaggcc
     8161 tcgatcgcgt ccggggtgcg cggcagcgcc cccgacatca gccgtgctcc ctcggccgtg
     8221 atgacgaggt cgtcctcgat gcgcacaccg ataccgcgca gttcgaccgg gagcgtctcg
     8281 tcgtccggct ggaggtagag gccgggctcg accgtcagca cctgtccctc ctccagcacc
     8341 ccgtcgagat aggccgtcgc ccgcgcctga gcgcagtcgt gcacgtcgag cccgagcatg
     8401 tgcccactgc tgcacagggt gtagcgccgg tggaactcgc cctcggggct ccccaggacg
     8461 ccccactccg tgagcccctc cgcgatcaac cgcatggcag caccgtggaa gtcacggaac
     8521 cgtgcccccg gcctgagcgc ggcgatgccc gcctcctggg cggcgagcac gagttcgtag
     8581 acctgccgct gcacgggcga gaaccgcccg gagagcggga gggtgcgcgt gatgtccgcg
     8641 gtgtacagac tgtccgtctc cacgcccgcg tccaggagca gcaactgtcg cgggtccagc
     8701 ggcccgtcgt tgcgtatcca gtgcaggacg caggcatggg cacccgccgc cgcgatggtc
     8761 tcgtagccgg tgccgttacc ctcggcgcgg gcacgcaggc cgaagacgcc ctcgatccag
     8821 cgctcacccc gcggatgggc gagtgctcgc ggcagggaac gcacgacatc ctcgaagccc
     8881 gcggcggtgt ggtccacggc gagttggagc tgctccacct cccaggcgtc cttcaccagc
     8941 ctcaactcgc tcagtgccga ggccagttcg gcgtcgacaa gggcgtcgcg gcccggcggc
     9001 agcgtccccc gcccctccag atcggcgcag cggatgccgg tcaggtgctc cgcctcggcc
     9061 aggtcggggc gccgtccgac ccagaactcg ccgtagcggc ggtcccggtg gaagccggcg
     9121 tcggtgcgcg gcgagcgcgg ccgcacatac agcaccgcct cgtgcccgtg cagcccgtcc
     9181 ggctccatga ccaggacgtg tccggcctgc tcctcaccgg tcaggccggt gagccaggcg
     9241 tacgcactgt gcggccggaa gcggtggtcg cagtcgttcg agcggacgct caactccccc
     9301 gccgggacga tgagccgctc gccggggaag cgggccgaca gccgggcacg gcggctgggc
     9361 gtgaggccgg cgacgggcag ccggacgtcg ccggcgagcg gggacggtgc ccagccgccc
     9421 gccatgaatg cctcgaactc cggtgacagc gggaggtcgt ggctgaccgt ccggtgggcg
     9481 ctcgccgcgg tttccttcat gcggtcctcc ttgattcgtg cgggcctctt gtgcagtaca
     9541 atttcacatt actatgttac gggtcacatt cagccggctc ggctgtccga ctgttcacgg
     9601 agtgaccact gatgaacaag cgcacccgca ccgccctcgc cgccgccctg gtgacgaccc
     9661 tcgccctcgg cgcggccggc tgctttggcg gcacgcggtc cacggacggc aaaggccgcg
     9721 gcacgaatcc cgccctcgcc aaccagggcg ccgccatcgg gggcaccccc acgaagggcg
     9781 gcaccctcac cgtcctgtcg aaccaggact tcacccacct cgaccccgcc cgcaactggg
     9841 tcatgggcga catggacttc ggcacccggc tgctctaccg caccctcgtc acgtaccgtg
     9901 ccgagccggg cgccggcggc ggggagctga cccccgacct cgccgcggac ctcggcacct
     9961 cctccaacgg ggccaggacc tggaccttca ggctcaagaa ggggctgaag tacgaagacg
    10021 ggtcgcccgt caccgcccac gacatcaagt acaacgtcga gcggtccttc tcccccgacc
    10081 tgcccggcgg ccccgactac gcggcccgct acctcgccgg cgccgagggc taccagggcc
    10141 cggccacggg aaagcacctc gactccgtca aggtgcccga cgaccacacg atcgtcttcg
    10201 aactgcgcaa gcccttcgcc gagttcccct acgccaccgt gctgccgacc ttcgcgccgg
    10261 tcccgaaggc gcgggacaag ggcccccggt acgacaaccg ccccttctcc tccggtccgt
    10321 acaggatcga gaggtacgca cgggacaagc agctggtgct ggtgcgcaac ccccactggg
    10381 acccgggttc cgacaccgtg cgcaaggcat acccggacag gatcgtcgtc acgatgggcc
    10441 tgaagggcaa ccagatcgac gaccgcctca tcgcctcctc cggcgccgac tcctccgccg
    10501 ttccctgggg caagctgcgc cccgaaagcg cctccaaagt gctcaccagg cccgacgtca
    10561 gggcccggtt gctggccgag tccaccaact gcaccgagat ggtgcagatg cacacgggcc
    10621 gggcgccgtt cgaccatgtg aaggtccgtc aggccgtgca gtacgccctc gaccgcgagg
    10681 ccgttctgac cgcatccggc ggcccggcgc tgggcgaccc ggccaccgcc ctcatgccgg
    10741 gctccctctt cggcggcagg cagcccgaca ccctgaagat ccccctcgcc ggtgacgtgg
    10801 cgaaggccag gcagctcctc aaggaggccg gccgcccgga cggcttcgcc accagcatca
    10861 ccgtctcgag cggcgacaag ggcgtgggcg aggcgatcca gcagtcgctc ggccgggccg
    10921 ggatcaaggt caccatcgag accgtcgacc cgtccgcctt ctacgacacg atcggcgaca
    10981 ccgagaaccg caccgacctc gtctacacgg gctggtgccc cgactacccg tccggctcca
    11041 ccttcctgcc cttcgtcttc gacggccgct acatcaagga gaagggcaac tccggcaacc
    11101 actcgctctt ccgcgacagg gtgaccatga aacggatgga cgagatcgcc gccatgaccg
    11161 acgcccggca ggccgccaag gcatggcagg acctggacgg acggatcctc gccgaggccc
    11221 ccaccgcacc cgccgtcatc gaacgcatgc cactgctgct cggcaccaac atcgccggag
    11281 cattcggtca cacctccttc ggcggccaga tcgactacgc caccgtcggc ctcaaggacc
    11341 ctgccaagag cggccgctga ggatccgacc gctcatggca gccaccactt ccccggccgt
    11401 ccctgcgggc cgcggcccct ggcagctcgc ccgcgcggaa ctgcgccggc ggacctccgt
    11461 gaagctctcc ctcgccgtgg tcgccctctt cgtcttcatg gcggcggccg ccccgctgct
    11521 cagttcgctg agcggctggg gccccgacga gttcgacaag agcgccgtcg acccctatct
    11581 cggcgggcag cccatcggac cgctcggcgg cgtctcggcc gagcactggc tcggcgtcga
    11641 acccgtcacc ggccgcgacc tgttcgcccg ggtcgtgcac ggcgctcagg tctcgctgct
    11701 catcgccttc gccgccacag ccatcgtcgt cgtcacgggt gtcgcggccg ggaccgcggc
    11761 cggctacttc ggcggcggca ccgacgccgt gctctcccgg ctgatggacc tgaccatgtc
    11821 cttcccttcc ctcatcttca tgatcgccat gatgtcggtg gcccgtgacg tcaaccggat
    11881 cgtgctgatg accgcggtca tcggcctctt cggctggccc ggcatcgccc gcgtcgtgcg
    11941 cggacagacg ctctcgctca agcaccgcga gtacgtcgac gccgcccgcg tcggcggcgc
    12001 cggtccctgg cgcatcctca cccgcgacat cctgccgggc gtggcgggac ccgtcatcgc
    12061 gtacaccacc ctgatcgtcc ccgggatgat cgccaccgag gccgccctga gctatctggg
    12121 cgtcggcgtc cgcccgccca ccgcgtcctg ggggcagatg atcgccgaga gcgtctcctt
    12181 ctacgacacg gatcccatgt acttcatcgt cccgagcacc tgcctgttcc tgacggtgct
    12241 tgccttcacc ctgctcggcg acgccctgag ggacatcctc gacccgagga gcgcccgcgc
    12301 atgatcctct acacgctgcg gcggctggcc gccgtcatcg gtgtgctgac cgccgtcgcc
    12361 gccgtcacct tcaccatctt ctacgtcctt ccctccgacc ccgcagccgc ggcctgcgga
    12421 aaggcgtgca gcgccgagcg actggccgcg atccgcgccc acatgggact cgaccagccg
    12481 ctgtggcggc agttctggga gttcgtcagc ggcatcttca ccggccgcac cacgggcagc
    12541 ggccagtacg ccatgcgctg cggcttcccc tgtctgggct actcgtacga gaacagtgag
    12601 gccgtctggg acctgttgac ggaccgcctg cccgtctccg cctcgctcgc gatcggcgcc
    12661 gcggcgctgt ggctggcact cggtctgagc gccggcacgg tcgcggccct gcgcaagggc
    12721 accctcaccg accgggtcct gatggtcggt gctgtcggcg cggcatcgct gccggtctac
    12781 ttcacctcga tgatgctgat ctacggcgtc atccgggtgg cgggcctgct cccctacccc
    12841 cagtacgtgc ccttcggcga cgacccggtg ggatgggcgt cgaacctcct gctgccctgg
    12901 ctggccctcg ccgtcctcta cgcggccatg tatgcgcgcc agagccgcag ttcgatgatc
    12961 gagacgatgg cggagccgta catccgcacc gcccgcgcca agggcctccc gcgccgcacc
    13021 gtcgtcgtca agcacggt
//
