LOCUS       NZ_BMWB01000001        26740 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces xantholiticus strain JCM 4863 sequence01, whole genome
            shotgun sequence.
ACCESSION   NZ_BMWB01000001
VERSION     NZ_BMWB01000001.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces xantholiticus
  ORGANISM  Streptomyces xantholiticus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 943286)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 114X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014651015.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:24:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,091
            CDSs (total)                      :: 7,016
            Genes (coding)                    :: 6,693
            CDSs (with protein)               :: 6,693
            Genes (RNA)                       :: 75
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 323
            CDSs (without protein)            :: 323
            Pseudo Genes (ambiguous residues) :: 0 of 323
            Pseudo Genes (frameshifted)       :: 187 of 323
            Pseudo Genes (incomplete)         :: 270 of 323
            Pseudo Genes (internal stop)      :: 13 of 323
            Pseudo Genes (multiple problems)  :: 140 of 323
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:39:19
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 285397
            Orig. end                         :: 312137
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMWB01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26740
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26740
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26740
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16740](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16740)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    362..380
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.71"
                     /tool="antismash"
     gene            1009..1938
                     /locus_tag="IE198_RS01320"
                     /old_locus_tag="GCM10010381_02710"
     CDS             1009..1938
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010473020.1"
                     /locus_tag="IE198_RS01320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_02710"
                     /product="STM4011 family radical SAM protein"
                     /protein_id="WP_189881721.1"
                     /transl_table=11
                     /translation="MDLTVLYRGPLASCDYDCPYCPFAKRRDSRQQLRADRAALERFTA
                     WAAAQTDDRLSVLFTPWGEGLVRSWYRKALTELSHLPHIRRVAIQTNLSCRTDWTADAD
                     PAKLALWCTYHPGQTPYDRFITKCRDLMRREIRFSVGIVGFPAHLAEAHRLRADLPPHI
                     YLWVNAPEGHELSDAEAEAWTELDPLFPYSRRPHRSAGLPCRTGESVISVDGEGTVRRC
                     HFVRAELGNLYDGSYRRALRPRGCPLAVCDCHIGYVHLETLPLYDVFAGGVLERIPTSI
                     PPAHSPVPPALDLLRAQSGSRSGRLAST"
     gene            complement(1899..2690)
                     /locus_tag="IE198_RS01325"
                     /old_locus_tag="GCM10010381_02720"
     CDS             complement(1899..2690)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552424.1"
                     /locus_tag="IE198_RS01325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_02720"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_189881723.1"
                     /transl_table=11
                     /translation="MADDSRTENSGAFGSYAAIGDSFTEGVGDPGPDGGFVGWADRFAV
                     LLADRIPEHSFRYANLAVRGRLLDQIVEEQVPRARELAPDLVTFCAGGNDIIRPGSDPD
                     DVAERFERAVADLAGSVGTVMVTTGFDTRDVPVLRHLRGRIATYTAHVRAIADRYDCPV
                     LDLWSLKSVQDRRAWDADRLHLSPEGHTRVALRAAQVLGLEVPADPDQPWPPLPPRGAL
                     EVRRDDIQWAREHLVPWIGRRLRGESSGDHVEAKRPDLLPL"
     gene            complement(2864..3811)
                     /locus_tag="IE198_RS01330"
                     /old_locus_tag="GCM10010381_02730"
     CDS             complement(2864..3811)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005308866.1"
                     /locus_tag="IE198_RS01330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_02730"
                     /product="M23 family metallopeptidase"
                     /protein_id="WP_189881725.1"
                     /transl_table=11
                     /translation="MPAKGKHRRPKSNPLTRGFVVAGTGGAAIALPLFGATTATAAPAA
                     APAAAPHKAAAPAVAESALPAAKKAPKTYTVVAGDCLSQIAEEQNVRGGWKQLFNDNRR
                     AIGSDPSLIHPGLELTIGAKSKAKNDPEPRSESQTRPSRDDSRSAAPEPEAPEKQAPAK
                     QAPAKEAPAKEASAPASSSGFTAPVDAAVTTPYRASGAMWSSGYHTGVDFAASSGTSVK
                     AIGAGTVVSAGWGGSYGNEVVIQHSDGTYSQYAHLSSLAVSTGQSVTGGQQIGLSGSTG
                     NSSGPHLHFEVRTGPSYGSDIDPLAYLREHGVSV"
     regulatory      complement(3816..3972)
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    3986..4000
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.09"
                     /tool="antismash"
     misc_feature    4053..4066
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    4098..4111
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.44"
                     /tool="antismash"
     misc_feature    5006..5020
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     misc_feature    5033..5047
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.94"
                     /tool="antismash"
     gene            5224..6036
                     /locus_tag="IE198_RS01335"
                     /old_locus_tag="GCM10010381_02740"
     CDS             5224..6036
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018100136.1"
                     /locus_tag="IE198_RS01335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_02740"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_189881726.1"
                     /transl_table=11
                     /translation="MTQQLPQAPSSEPDLTGVRNFRDVGGLPTVDGRRVRPGRLFRSGH
                     LAHASAADAAFLSTLGLHTIFDFRNAADQRLEGPDIELPGVRNINLPLSDPADGAEFWK
                     MVREGNLDQLKAILADGKGAGRMITSYRMIIKERTGEHSQVLHALAEDSVPALMHCAAG
                     KDRAGLSIAVSLLAVGVERDAIEADYLKSNDPHRRYKVRRSDSSPDAMSPEVMELLSPL
                     FDARAEYLAAAFDAIEEHWGTTERYLSEGLRLAPATRERLRERLLEEG"
     gene            complement(6046..6219)
                     /locus_tag="IE198_RS01340"
                     /old_locus_tag="GCM10010381_02750"
     CDS             complement(6046..6219)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955417.1"
                     /locus_tag="IE198_RS01340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_02750"
                     /product="DUF6126 family protein"
                     /protein_id="WP_373299759.1"
                     /transl_table=11
                     /translation="MHDMSHDPLDPRGSAGDSPHEERFPRGLVIRLFAYLIAGHIIAGF
                     LYLLFLVGGQNR"
     gene            complement(6219..6821)
                     /locus_tag="IE198_RS01345"
                     /old_locus_tag="GCM10010381_02760"
     CDS             complement(6219..6821)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018848327.1"
                     /locus_tag="IE198_RS01345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_02760"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_189881728.1"
                     /transl_table=11
                     /translation="MTTPAASAAEGLPEMAPRLRELRRRRGLTLEAAARRAGLSPAHLS
                     RLETGLRQPSLPMLLALARIYGTTVAELLGEQPPEREPVIRGRHREPVPAGAWDYHQAG
                     SPGRAMQALRVFVPHGVQGDLVRVHPGEEWLHVVAGRLRLSLGDAVHELAPGDSAHFDS
                     ITPHRIAADSPEGAELLFVHTLLQAPELHPLPDRQGK"
     gene            complement(6886..8280)
                     /locus_tag="IE198_RS01350"
                     /old_locus_tag="GCM10010381_02770"
     CDS             complement(6886..8280)
                     /NRPS_PKS="Domain: Aminotran_3 (45-366). E-value: 1.5e-85.
                     Score: 279.1. Matches aSDomain:
                     nrpspksdomains_IE198_RS01350_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018848328.1"
                     /locus_tag="IE198_RS01350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_02770"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_189881729.1"
                     /sec_met_domain="Aminotran_3 (E-value: 4.5e-85, bitscore:
                     281.4, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEQPKGFDLADLLARRGGERYELHARYLNHQLPRMLRTIGFDKI
                     YERAQGAYFYDTEGNDYLDMLAGFGVMGLGRHHPVVRKALHDVLDSSLADLTRFDCQPL
                     PGLLAEKLLTHTPHLERVYFGNSGAEAVEAALKFARYATGRPRVVYCTHAFHGLTAGAL
                     SVNGEAGFREGFAPLLPDTAIAMGDLAALERELVRGDVAAFVVEPIQGKGVYPTPPGFL
                     RAAQELLHKYKALLIVDEVQTGLGRTGDFYGFQYEAGVEPDLVCVAKALSGGYVPVGAT
                     LGRDWIFRRVYSSMDRVLVHSASFGGGAQAMAAGLAVLSVLEDEHIVANARVTGELLRA
                     RLAALVDRYELLHAVRGRGLMIGIEFGRPDSIKLRSRWTVLQAARKGLFAQMVVVPLLQ
                     KHRILTQVSGDHMEVIKLIPPLIIGEREVDRFVAAFTAVMDDAHGSGGLMWDFGKTLVK
                     QAVAHR"
     aSDomain        complement(7183..8145)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS01350_Aminotran_3.1"
                     /evalue="1.50E-85"
                     /label="IE198_RS01350_Aminotran_3.1"
                     /locus_tag="IE198_RS01350"
                     /protein_end="366"
                     /protein_start="45"
                     /score="279.1"
                     /tool="antismash"
                     /translation="YERAQGAYFYDTEGNDYLDMLAGFGVMGLGRHHPVVRKALHDVLD
                     SSLADLTRFDCQPLPGLLAEKLLTHTPHLERVYFGNSGAEAVEAALKFARYATGRPRVV
                     YCTHAFHGLTAGALSVNGEAGFREGFAPLLPDTAIAMGDLAALERELVRGDVAAFVVEP
                     IQGKGVYPTPPGFLRAAQELLHKYKALLIVDEVQTGLGRTGDFYGFQYEAGVEPDLVCV
                     AKALSGGYVPVGATLGRDWIFRRVYSSMDRVLVHSASFGGGAQAMAAGLAVLSVLEDEH
                     IVANARVTGELLRARLAALVDRYELLHAVRGRGLMIGIEF"
     gene            complement(8323..9342)
                     /gene="hpnH"
                     /locus_tag="IE198_RS01355"
                     /old_locus_tag="GCM10010381_02780"
     CDS             complement(8323..9342)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128938.1"
                     /locus_tag="IE198_RS01355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_02780"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_189881730.1"
                     /sec_met_domain="PF04055 (E-value: 5.5e-18, bitscore: 61.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 8.7e-09, bitscore: 30.9,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQTIRVGTYLFEQKLRRRDKFPLIVELEPLYACNLACEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVRRRKYVF
                     LCTNALLLRKKIDKFTPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVAAIEEAKRRGF
                     RVTTNSTFFNTDTPQTVVEVLNYLNDDLKVDEMMISPAYAYEKAPDQEHFLGVEQTREL
                     FRKAFAGGNRRRWRLNHSPLFLDFLEGKADFPCTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRELVEETDWDKYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESLRAARETLSGGR"
     gene            complement(9348..10001)
                     /locus_tag="IE198_RS01360"
                     /old_locus_tag="GCM10010381_02790"
     CDS             complement(9348..10001)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005308884.1"
                     /locus_tag="IE198_RS01360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_02790"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_189881731.1"
                     /transl_table=11
                     /translation="MADSSKPSGSAVPLLIACALGIEKFALRAGDRGGAAGDVTVLRTG
                     MGPVNAGRAVRVACRTTALAEAAVVASGFCAGLAPGMHPGDLVVVEEVRLGGSPTACTN
                     TELLAEAVARAAPGRTVHTGPLTGVDHVVRGHERARLLGTGAIAADMESAATLSSALEA
                     GPRPLAAVRVVVDAPEHELVRIGTLRGGISAFRVLRAVMPAFFEWHRSLLLPRR"
     gene            complement(10001..12037)
                     /gene="shc"
                     /locus_tag="IE198_RS01365"
                     /old_locus_tag="GCM10010381_02800"
     CDS             complement(10001..12037)
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152781.1"
                     /locus_tag="IE198_RS01365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_02800"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_189881733.1"
                     /sec_met_domain="T2TS (E-value: 1.6e-153, bitscore: 507.8,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSSGPLRGGAATAGETTSTSAARTTEPGTDLREAAARAA
                     ERAVEHLLARQDAEGWWKGDLETNVTMDAEDLLLRQFLGIQDPATVEASARFIRGQQRD
                     DGTWATFYGGPGELSTTVEAYVALRLAGDRPDDPHMQRAASWVRSRGGIAASRVFTRIW
                     LALFGWWKWEDLPELPPELIFLPKWFPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFA
                     LDELHTDRALPNPGKRLAPAASWDGFFQRADKALHAYHKVAPRRLRRAAMNAAARWIIE
                     RQENDGCWGGIQPPAVYSVIALHLLGYDLEHPVMRAGLESLDRFAVHHEEEGLPVRMIE
                     ACQSPVWDTCLATIALADAGLPADHPALVKAADWMLSEQVVRPGDWSVRRPGLGPGGWA
                     FEFHNDNYPDIDDTAEVVLALRRVKHPDPERVDAAVARGTRWNLGMQSRDGAWGAFDAD
                     NTSPFPNRLPFCDFGEVIDPPSADVTAHVVEILAHEGMAHDPRTRRGVRWLLAHQEANG
                     AWFGRWGVNYVYGTGAVVPALTAAGLPGSHPAIRRAVAWLESVQNEDGGWGEDLRSYRE
                     ERSIGHGASTASQTGWALLALLAAGERESKAVERGVAHLAQTQAPDGSWDEPYFTGTGF
                     PWDFSINYHLYRQVFPLTALGRYVYGEKLPGRAGARSGAREGG"
     misc_feature    complement(12091..12106)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.94"
                     /tool="antismash"
     gene            complement(12206..13282)
                     /locus_tag="IE198_RS01370"
                     /old_locus_tag="GCM10010381_02810"
     CDS             complement(12206..13282)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019993176.1"
                     /locus_tag="IE198_RS01370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_02810"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_189882750.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.1e-58, bitscore:
                     193.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHSAYPADDTAQSAESVDVSALLERGRTLSTPVLRAAVGRLAPPM
                     DTVAAYHFGWIDAQGRPSDGDGGKAVRPALALLSAEAAGAAPEVGVPGAVAVELVHNFS
                     LLHDDLMDGDEQRRHRDTVWKVHGPAQAILVGDALFALANEVLLEIGTVEAGRATRRLT
                     TATRKLIDGQAQDISYEHRERVTVEECLEMEGNKTGALLACAVSIGAVLGGADDRTADT
                     LESYGYHLGLAFQAVDDLLGIWGDPVATGKQTWSDLRQRKKSLPVVAALAAGGPASERL
                     GELLAADAKSNDVDSFSEEEFATRAALIEEAGGREWTSQEARRQHAVAIEALSGVDMPE
                     RVRAQLVALADFVVVRKR"
     gene            complement(13321..14709)
                     /gene="hpnE"
                     /locus_tag="IE198_RS01375"
                     /old_locus_tag="GCM10010381_02820"
     CDS             complement(13321..14709)
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018848333.1"
                     /locus_tag="IE198_RS01375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_02820"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_189881735.1"
                     /sec_met_domain="DAO (E-value: 2e-10, bitscore: 36.5,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPDTLGARHAVVVGGGIAGVTAALQLADAGVGVTLLESRPRLG
                     GLAFSFRRGALTVDNGQHVHLRCCTAYRWFLDRIDGAHLAPVQNRLDVPVLDVAAKGGP
                     RLGRLRRSALPVPLHLGASLARYPHLSLAERAGVGRAALALGRLDPADPALDGIDFAGW
                     LGRHGQSPRAVAALWDLVGVATLNARAPQASMGLAAMVFKTGLLSEPGAADIGWARVPL
                     GELHDTLARKALDSAGVRTELSTRVREINRSADGRWQVVVDGEELHADVVVLAVAQREA
                     HALLPDGALEDPDRLLDIGTAPILNVHVLYDRKVLRRPFFAALGTHVQWVFDRTAASGA
                     KEGQYLAVSQSAAQDEIDEPVSVLRKRYLPELERLLPAARGAQVRDFFVTRERTATFAP
                     SPGVGRLRPVARTRARGLYLAGAWTATGWPATMEGAVRSGFSAAGAALSALGRRHEHPL
                     EEAA"
     gene            complement(14873..15823)
                     /gene="hpnD"
                     /locus_tag="IE198_RS01380"
                     /old_locus_tag="GCM10010381_02830"
     CDS             complement(14873..15823)
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072792.1"
                     /locus_tag="IE198_RS01380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_02830"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_189881737.1"
                     /sec_met_domain="phytoene_synt (E-value: 3.6e-59, bitscore:
                     195.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.7e-70,
                     bitscore: 233.4, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRTMEGPTVVPAPVQAAYSYCEAVTGQQARNFAYGIRLLPTHKR
                     QAMSALYAFSRRVDDIGDGKLKPQAKQDRLEGTRELLERIRRGAVDEDDTDPVAVALSD
                     AARRFPLPLGGLDELIDGVLMDVRGESYETWDDLKVYCRCVAGAIGRLSLGVFGTQPGA
                     RGSERAAEYADTLGLALQLTNILRDVTEDAANGRTYLPADDLAKFGCSEGFHGTTPRPG
                     ADFTGLVHFEVRRARALFAEGYRLLPMLDRRSGACVAAMAGIYRRLLDRIEREPEAVLR
                     GRVSLPGREKAYVAVRGLSGLDARLIGRQTQGGRR"
     gene            complement(15820..16740)
                     /gene="hpnC"
                     /locus_tag="IE198_RS01385"
                     /old_locus_tag="GCM10010381_02840"
     CDS             complement(15820..16740)
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005308894.1"
                     /locus_tag="IE198_RS01385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_02840"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_189881739.1"
                     /sec_met_domain="phytoene_synt (E-value: 5.3e-37, bitscore:
                     123.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.7e-39,
                     bitscore: 131.5, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGTARTGARVPARATLDKAADENFPVAPFFLPRAWRDDLMAVYG
                     YARLVDDIGDGDLAPGGADAHHLGVAPELADDRLALLDAFEADLRRVFDASGAAPHHPL
                     LHALRPTVRRCSLTPEPFLGLIAANRQDQLVRRYQTYDDLLAYCELSANPVGRLVLGIT
                     GTTTPERVRRSDAICTGLQIVEHLQDVAEDLARDRIYLPAESMKRFHVAEADLAAPTAN
                     ASVRALVAHEGRRARALLDEGTPLVGSVEGRLRLLLAGFVAGGRAALAAIAAAGHDVLP
                     GPPRATRTNLLREVGAVLRRARREG"
     misc_feature    16983..16995
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.42"
                     /tool="antismash"
     gene            complement(17176..17949)
                     /locus_tag="IE198_RS01390"
                     /old_locus_tag="GCM10010381_02850"
     CDS             complement(17176..17949)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019890658.1"
                     /locus_tag="IE198_RS01390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_02850"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_189882752.1"
                     /transl_table=11
                     /translation="MAGARVPTVIADDVHIVYRVNAGGGGRGSATAALSRILRRDKGES
                     RGVRKVHAVRGVSFTAYRGEAIGLIGSNGSGKSTLLRAIAGLLPAESGKVYTDGQPSLL
                     GVNAALMNDLTGERNVILGGLAMGMSREEIRERYQGIVDFSGINEKGDFITLPMRTYSS
                     GMAARLRFSIAAAKDHDVLMIDEALATGDRRFQIRSEERIRELRKEAGTVFLVSHSNKS
                     IRDTCDRVLWLEKGELLMDGPTDEVIKAYEKETGK"
     gene            complement(17963..18892)
                     /locus_tag="IE198_RS01395"
                     /old_locus_tag="GCM10010381_02860"
     CDS             complement(17963..18892)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964854.1"
                     /locus_tag="IE198_RS01395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_02860"
                     /product="ABC transporter permease"
                     /protein_id="WP_189881741.1"
                     /transl_table=11
                     /translation="MSDTTHDGAVAMSPAPSPDDGLSPSQLAAKYGLSVSGARPGLVSY
                     VRQLWGRRHFILAFSQAKLTAQYSQAKLGQLWQVATPLLNAAVYLVIFGVILKTSRGMP
                     MDVYIPFLVTGVFAFTFTQSSVMAGVRSISGNLGLVRALHFPRASLPISFALQQLQQLL
                     FSMIVLLAIVVGFGSYPALSWLLAVPALVLQFVFNTGLAMIMARLGAKTPDLAQLMPFI
                     MRTWLYASGVMFSIPVMLADKPAWIAEVLMYNPAAVYMDLIRFALIDGYGSENLPSHVW
                     AAGLGWAVLVGFAGFVYFWKAEERYGRG"
     gene            complement(18980..19864)
                     /locus_tag="IE198_RS01400"
                     /old_locus_tag="GCM10010381_02870"
     CDS             complement(18980..19864)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972240.1"
                     /locus_tag="IE198_RS01400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_02870"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_189881743.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.2e-10,
                     bitscore: 37.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPLKLGAVVITMGTRPDELRALLDSVAKQDGDPIQVVVVGNGA
                     PVVDVPEGVRTVDLPENLGIPGGRNVGIEAFGPGGRDVDVLLFLDDDGLLPDTGTARLV
                     REAFDADPGLGIVSFRIADPETGLTQRRHVPRLRASDPMRSSRVTTFLGGANAVRTKVL
                     GEVGGLPDEFFYAHEETDLAWRALDAGWSIEYRADMLLLHPTMPPSRHAVYHRMVARNR
                     VWVARRNLPLPLVPVYLAVWVLLTLLRRPSLPALKAWFGGFAEGWRTPCGPRRPMKWRT
                     VWRLTRLGRPPVI"
     gene            complement(19861..20640)
                     /locus_tag="IE198_RS01405"
                     /old_locus_tag="GCM10010381_02880"
     CDS             complement(19861..20640)
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049651.1"
                     /locus_tag="IE198_RS01405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_02880"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_189881745.1"
                     /transl_table=11
                     /translation="MPRPSVAELRPVVHPAGVKDRRSGEHWAGRLYMREISLRVDRYLV
                     NTAITPNQLTYLMTLAGVLAAPALLVPGIWGAVLGVVAVQLYLLLDCVDGEIARWKQQF
                     SLSGVYLDRVGAYLCDAAVLVGFGLRAADLWGSGRIDWLWAFLGTLAALGAILIKAETD
                     LVGVARHQGGLPPVKEAAAEPRSSGVALARRAAAALKFHRLVLGIEASLLILLLAVLDQ
                     VRGDLFFSRLGVAVLAGIALLQTLLHLVSVLASSRLK"
     gene            complement(20618..21679)
                     /locus_tag="IE198_RS01410"
                     /old_locus_tag="GCM10010381_02890"
     CDS             complement(20618..21679)
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007452391.1"
                     /locus_tag="IE198_RS01410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_02890"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_189881747.1"
                     /sec_met_domain="Fe-ADH (E-value: 3.7e-23, bitscore: 77.6,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 3.8e-09, bitscore:
                     31.8, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRAGALDDLAGILADQRISSSGRLAFAISG
                     GSGQKLREKVAPALTGADWYEVCDGTIDSAVKLADDMKGNRYDAVVGLGGGKIIDVAKY
                     AAARVGLPLVAVATNLAHDGLCSPISILDNDNGRGSYGVPSPIAMVIDLDVVREAPVRF
                     VRSGIGDAISNISAIADWELSHRIKGENVDGLAAAMARTAGESVLRHPGGVGDDEFLTV
                     LAEALVLSGIAMSISGDSRPSSGACHEISHAFDLLYPKRAASHGEQCGLGAAFAMHLRG
                     AHEQAGLFAEVLRRHGLPVTPDEIGFSPDEFVRAVEYAPQTRPGRFTILEHLDLTHDQI
                     RDAYADYAKTISS"
     gene            complement(21667..22404)
                     /locus_tag="IE198_RS01415"
                     /old_locus_tag="GCM10010381_02900"
     CDS             complement(21667..22404)
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955403.1"
                     /locus_tag="IE198_RS01415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_02900"
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="WP_189881748.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 3.1e-12, bitscore:
                     42.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVDGETTVLDLTLGNFAEI
                     GLTEAAIVVGYRKEAVYERRAALEAKYGLKLTLVDNDKAEEWNNAYSLWCARDVIAEGV
                     ILANGDTVHPVSVEQTLLAARGNGQKIILALDTVKHLADEEMKVITAEGKGVQRITKLM
                     DPATATGEYIGVTLIEPDAAADLADALRATFERDPDLYYEDGYQELVNRGFTVDVAPIG
                     DVKWVEIDNHDDLAKGREIACQY"
     gene            complement(22401..24215)
                     /locus_tag="IE198_RS01420"
                     /old_locus_tag="GCM10010381_02910"
     CDS             complement(22401..24215)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996269.1"
                     /locus_tag="IE198_RS01420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_02910"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_189882754.1"
                     /transl_table=11
                     /translation="MSTAILTGPPAPGSSLEGDLRSLGFDVRVANGPEHTAALISAVPA
                     AERVALVDPRFVGHVHALRLALTDPRFPAASVTGALTAQPAGRVALAGAVRAVSATVPA
                     GAGAVAGDGVVDSVIAELEAQGVAVHHPELGSLIAAVPSEAAERHRVRAAVEAVDDEAV
                     RLRSAVKARDGFFTTFCISPYSRYIARWCARRGLTPNQVTTASLLTALIAAGCAATGTR
                     AGFVAAGLLLLFSFVLDCTDGQLARYSLQYSTMGAWLDATFDRAKEYAYYAGLALGAAR
                     GGDDVWALALGAMVLQTCRHVVDFSFNEANHDATANTSPTAALSSKLDSVGWTVWLRRM
                     IVLPIGERWAMIAVLTAVTTPRIVFCALLVGCALAACYTTAGRVLRSLTRKAHRTDRAA
                     QALADLADSGPAAEAVARVTARTARSLPGIAPLAAAVAGAAALVATAAFTGFGSVWTVV
                     AALGYAATSGIAVARPLKGALDWLVPPVFRAAEYGTILVLAAHAGVNGALPAAFGLIAA
                     VAYHHYDTVYRIRGGTGAPPHWLVRTIGGHEGRVLAVTLLALLPGATDFTIALTVLAVA
                     VALVVLVESIRFWVSSQAPAVHDEGEPA"
     misc_feature    complement(24359..24374)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.41"
                     /tool="antismash"
     misc_feature    24360..24374
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: strong, score: 21.84"
                     /tool="antismash"
     gene            24481..25464
                     /gene="galE"
                     /locus_tag="IE198_RS01425"
                     /old_locus_tag="GCM10010381_02920"
     CDS             24481..25464
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (65-205). E-value:
                     5.3e-10. Score: 30.8. Matches aSDomain:
                     nrpspksdomains_IE198_RS01425_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018888986.1"
                     /locus_tag="IE198_RS01425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_02920"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_189881750.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 8e-17, bitscore:
                     57.0, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 5.6e-14,
                     bitscore: 47.6, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLITGGAGYIGAHVAHAMTAAGERVVVLDDLSSGIPGRLPAGV
                     PLVRGSVLDRDAVDRVLAGHAVTGVVHLAAKKQVGESVEQPLRYYRENVYGLTVLLEAV
                     VAAGVQRFLFSSSAAVYGVPDTDLVSESAACEPINPYGETKLTGEWLVRAAGRAHGLST
                     ACLRYFNVAGAAAPELADTGVFNIIPMFFDRITRGEAPRIFGADYPTPDGTCIRDYIHV
                     ADLADAHLAVARRLAGTEAGKDLTVNIGRGVGVSVRELARVVGEVTGRHFDPVVEPRRA
                     GDAAKAVASVELIAEELGWTASYGVRDMVASAWAGWSARHPETAAH"
     CDS_motif       24484..24570
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE198_RS01425_0001"
                     /evalue="1.80E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE198_RS01425"
                     /protein_end="30"
                     /protein_start="1"
                     /score="17.4"
                     /tool="antismash"
                     /translation="TWLITGGAGYIGAHVAHAMTAAGERVVVL"
     aSDomain        24676..25095
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE198_RS01425_NAD_binding_4.1"
                     /evalue="5.30E-10"
                     /label="IE198_RS01425_NAD_binding_4.1"
                     /locus_tag="IE198_RS01425"
                     /protein_end="205"
                     /protein_start="65"
                     /score="30.8"
                     /tool="antismash"
                     /translation="AVTGVVHLAAKKQVGESVEQPLRYYRENVYGLTVLLEAVVAAGVQ
                     RFLFSSSAAVYGVPDTDLVSESAACEPINPYGETKLTGEWLVRAAGRAHGLSTACLRYF
                     NVAGAAAPELADTGVFNIIPMFFDRITRGEAPRIFG"
     misc_feature    complement(25512..25526)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            25616..26557
                     /locus_tag="IE198_RS01430"
                     /old_locus_tag="GCM10010381_02930"
     CDS             25616..26557
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049646.1"
                     /locus_tag="IE198_RS01430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010381_02930"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_189881752.1"
                     /transl_table=11
                     /translation="MGAGHDHGHGHGGPPPTGTAAALYKGRLRIALAITLGVMVLEIIG
                     GVLSGSLALIADAAHMATDAVGLAMALLAIHFANRPAGQNRTFGFARAEILAALANCLL
                     LIGVGGFLLFEAVERFIEPAQTRGGLTVVFALVGLVANMVSLTLLMRGQKESLNVRGAY
                     LEVLADALGSVTVLISAGIILGTGWQYADPIASLAIGLMIVPRTWRLLRETLNVLLEAA
                     PQGVDMGDVRAHILALPGVEDVHDLHAWTITSGMPVLSAHVVVSQDVLDSVGHEKMLHD
                     LQGCLGAHFDVEHCTFQLEPVGHAEHEAKLCH"
ORIGIN
        1 gacggcgggt gagttggagc ggctctgcga catcgcggag aagcggatgg gggcggacct
       61 gacggcggtg ccgctctccg tcgagacctc cccggcgacg gcaacggccg accggctggc
      121 cgtgctcgcc gagcgcggca cgacccgcgt cagcatcggc gtgcagagct tcgtcgacgt
      181 ggaggcgcgg gccgcggtcc gtccgcagcg ccgggccgac gtcgaggccg cgctcggccg
      241 gatacgggac gccgagatcc cggtcctcaa catcgacctc atctacggca tcgacggcca
      301 gagtgagcgg acctggctct cctcgctcga cgccgccctc ggctgggagc cggaggagct
      361 gtatctgtat ccgctgtacg tacggccgct gaccggtctg ggccgcctcg gcgccgcggc
      421 cgacgccgcc tgggacgagc agcggctgcg gctgtaccgc acgggccgcg atcatctgct
      481 cgcccgcggg tacgagcagg tgtccatgcg catgtttcgc cgcgccggcg ccccgccctc
      541 cggcgccgac gaccacgctt gccagacgga cggcatgatc gggctgggct gcggcgcccg
      601 ctcctacaca tctgccctgc attactcctt cgactatgcc gtcggcatgg gtgaggtacg
      661 gcgcatcatc gacgacttca ccaccaccat ggacttctcc cgcgcggagg tgggccgccg
      721 ggtcgacgag ggcgaggcgc gccgccgcca tctcctccaa tcactgctgc aggcggaggg
      781 tatggaggtg gccggctacc gcgagcggtt cggcgccgct cccgccgacc actttccggc
      841 ggagctggag cggttcgccg cgctcggctg gcttgactcg gccgccgccc ccggccggtt
      901 gcggctgtct ccggagggac tggcccattc ggacgccctg ggtcccgagc tgttctcgcc
      961 cgcggtgcgc gccgcgatgg ccgcgtacga gccgaagtga gcggggccat ggatctgacc
     1021 gtgctgtacc ggggcccgct cgcctcgtgc gactacgact gcccctactg cccgttcgcg
     1081 aagcggcgcg acagccggca gcagcttcgc gccgaccggg cggcgctgga gcgcttcacg
     1141 gcgtgggccg cggcgcagac cgatgaccgg ctgtcggtgc tgttcacccc gtggggggag
     1201 ggcctggtcc gctcctggta caggaaggca ctgaccgagc tgtcgcatct gccgcacatc
     1261 cgccgggtgg cgatccagac gaacctcagc tgccgcaccg attggacggc ggacgcggat
     1321 ccggcgaagc tcgccctgtg gtgcacgtat caccccgggc agacccctta tgaccggttc
     1381 atcaccaagt gtcgggatct gatgcggcgg gagatccggt tcagcgtcgg catcgtcggc
     1441 tttcccgccc acctcgcgga ggcgcacagg ctccgcgccg atctgccgcc gcacatctac
     1501 ctgtgggtga acgcgcctga gggccacgag ctctccgacg ccgaggccga agcctggacg
     1561 gagctggacc cgctgttccc ctacagccgc cgtccgcacc gctccgccgg gctgccgtgc
     1621 cgcaccggtg agtcggtgat ctcggtggac ggcgagggga ccgtccggcg ctgccacttc
     1681 gtccgcgccg agctgggcaa tctctacgac ggctcgtacc gccgcgcgct gcgcccccgg
     1741 gggtgcccgc tcgccgtgtg cgactgccac atcggctacg tccacctgga gacgctgccg
     1801 ctgtacgacg tcttcgccgg cggcgtcctc gaacggatcc ccacgtcgat tcccccggcg
     1861 cactccccgg tgccccccgc gcttgacctc ctgcgcgctc agagcggtag caggtccggg
     1921 cgcttggcct ccacatgatc accggagctc tcgccgcgca accgccgccc gatccacggc
     1981 accaggtgct cacgcgccca ctggatgtcg tcccggcgga cctccaacgc cccgcgcggg
     2041 ggcagcggcg gccacggctg gtccgggtcg gccggcacct ccaacccgag gacctgcgcg
     2101 gcgcggagcg cgacccgggt gtgcccctcg ggtgacagat gcagccggtc ggcgtcccaa
     2161 gcacgccggt cctggacgga cttgagcgac cacaggtcca gcaccgggca gtcgtagcgg
     2221 tctgcgatgg cccgcacatg ggcggtgtac gtggcgatcc tgccgcgcag atggcgcagg
     2281 accggcacat cgcgagtgtc gaaaccggtg gtcaccatga cggtgccgac cgagcccgcg
     2341 aggtcggcga cggcccgctc gaagcgttcg gccacgtcgt ccgggtcgga gccgggccgg
     2401 atgatgtcgt tgccgccggc acagaaggtc acgaggtcgg gtgcgagctc gcgcgccctc
     2461 ggcacctgct cctcgacgat ctggtcgaga agccgcccac ggacggcgag attggcgtac
     2521 cggaaggagt gctccggaat gcggtcggcg agcaggaccg cgaaccggtc cgcccacccg
     2581 acgaagcctc cgtcgggtcc ggggtcgccc acgccctcgg tgaagctgtc accgatcgcc
     2641 gcgtacgacc cgaatgcgcc actgttctct gttctcgaat cgtctgccac gggagcacat
     2701 ctttccttca cggatgtgac ctacgcgacc gtaaggaggg gttgacgtgg agtgatcttt
     2761 gccacccgtc aagtttcgac caagccggaa tacgcggaag tccccgctcc gccggtgcgg
     2821 aacggggact tcgcgacaat tgccggacgg cgtgccgcag gtatcagacg gagactccgt
     2881 gctcgcgcag ataggccagc gggtcgatgt ccgagccgta ggacggaccg gtgcgcacct
     2941 cgaagtgcag gtggggaccg gaggagttgc ccgtggagcc ggacagaccg atctgctggc
     3001 cgccggtcac ggactggccg gtggagacgg ccagggagga gaggtgggcg tactgggagt
     3061 aggtgccgtc cgagtgctgg atgacgacct cgttgccgta cgagccgccc catccggcgg
     3121 agacgacggt gcccgcaccg atggccttga cggaggtgcc cgaggaggcg gcgaagtcca
     3181 cgccggtgtg gtagccgctg gaccacatgg cgccggaggc gcggtacggc gtggtgacgg
     3241 cggcgtcgac cggagcggtg aacccggagg aggacgcggg ggccgaggcc tccttcgcgg
     3301 gagcttcctt tgcgggagcc tgcttcgcgg gagcctgctt ctccggcgcc tcgggctcgg
     3361 gcgcggcgga ccgcgagtcg tcacgcgagg ggcgggtctg ggactccgag cggggctcgg
     3421 ggtcgttctt cgccttggac ttcgcgccga tcgtcagctc cagacccggg tggatcaacg
     3481 aggggtcgga accgatggcg cggcggttgt cgttgaagag ctgcttccag ccgccgcgga
     3541 cgttctgctc ttcggcgatc tgcgacaggc agtcgccggc gacgacggtg tacgtcttgg
     3601 gggccttctt ggcggccggc agggccgact cggcgactgc cggggcagcg gccttgtgcg
     3661 gcgcggcggc cggagccgcc gccggggcgg cggtggcggt cgtggcgccg aacagcggga
     3721 gcgcgatggc ggcgccgccc gtaccggcga cgacgaagcc gcgggtgagg gggttggact
     3781 tgggacgacg gtgcttaccc tttgcgggca tggcgcattc ctctccggcg cctgcgaggt
     3841 gagctgtcgg gttcgggctg gagatgcccg gtcgcgcata ttgctcgact tcaccccaag
     3901 ccgtccgaat tttccggaat cggcgtacta cctgggtccc ccgctcctgc cacacgtggg
     3961 tgggttcgaa ttccggccgg cggcaggatt aggcggtccg tccggattga gcgtgaccgt
     4021 aggtgagtag ggcagtcatg gacaagccgc aattttccgc gatcaatgga aagcattgaa
     4081 tcactcgggc atttccggtc accctccgtg gacgacgccc cttcaattac cttgctgccc
     4141 aaggaattca tcgcccggct cccgccacac aacgtcacgg atatgacgct gctcaccaac
     4201 cggaacccat ctcccctgct tacggggcac gttataccga accagccaat tcggacagaa
     4261 gcagcatttg accctctagt tccgtaaagg ggattcggcg aaaacggatc atctccgcca
     4321 cagcatctgg cgcccgcgac catcgcacag cgtggcgccg ggatccccct ccagctcggt
     4381 gtggagtccg tccatggcgc agcagcgccc caccccgatg gacggctccg gtgtccacgt
     4441 atgcgtgagt ggccgccggg ccgatgggcc acagccggag cgccggcggc agcgccgtgg
     4501 cgcagcgctt ccagcggcgc gaaaacgacc gtctcgtcgc ccggacgtac cgcacggcgc
     4561 tgggcccgcc tccggagtcg gcagtgggta cggctcgccg tacgggaact gtccgcattg
     4621 accatctacg gctccgcacg gatgccgaaa tgcctgccgg gcgcgtgcac ttcacgggcg
     4681 agcggcgccg gctctcgggg aagcggtccg gattcggtgt ctgcgtgcgg accggcggca
     4741 ccgggcacac gaaggaggac cgcctgcgac ggggaactcc tcacggcggt ccagcgggga
     4801 ctcgaaggcc ccccggggct tccggcccct gcgccgccgg cgcttcgacg gcggcacttc
     4861 ggcgtcgccg tcggcggggc gtcggcggcg gcggggcgtc ggcggcggtg acgtgcgtcc
     4921 cccggcgcag aggtcagctc gtccacgtcg gcgaggggaa agcgcactca cgagcccgga
     4981 gaggacccgc atacgcccca tttgccgacg ctctcggcca ccccacccct cagattttca
     5041 cagaatcaaa cagcctcgaa catcagggcg ggagcctggc agccgcaacg ccatggagtc
     5101 gcggagggtg tcaaccccct taccccaagg ccaagatgat tgcctgatga atccgtgtcg
     5161 tatggtcgag gccgctccgt cgtcggcgag cagcgccggc cactgtcccc cgaaggagtc
     5221 cccgtgacgc agcagctgcc gcaggccccg tcgtcagagc ccgacctgac cggtgtgcgc
     5281 aacttccgcg acgtgggcgg actgccgacc gtggacgggc ggcgggtgcg tcccggcagg
     5341 ctgttccgca gcggccacct ggcacacgcg tcggcggccg acgccgcgtt cctgtcgacg
     5401 ctcggcctcc acacgatctt cgacttccgc aacgccgccg atcagcggct ggaggggccg
     5461 gacatcgagc tccccggcgt gcgcaacatc aatctgccgc tgagcgaccc ggcggacggg
     5521 gccgagttct ggaagatggt ccgcgagggg aacctggacc agctcaaggc gatcctcgcc
     5581 gacggcaagg gcgccggacg catgatcacc tcttaccgca tgatcatcaa ggagcggacc
     5641 ggggaacaca gccaggtgct gcacgccctg gccgaggaca gcgtcccggc cctgatgcac
     5701 tgcgccgcgg gcaaggaccg tgccgggctg tcgatcgccg tctccctcct cgccgtcgga
     5761 gtggagcgcg acgccatcga ggcggactac ctcaagtcca acgacccgca ccggcgttac
     5821 aaggtccggc gcagcgacag ctcgcccgac gcgatgtccc cagaggtgat ggagctgctc
     5881 agcccgctct tcgacgcccg ggcggagtat ctggccgcgg cgttcgacgc catcgaggag
     5941 cactggggca cgacggagcg ctatctcagc gagggcctgc gactcgcccc ggcgacgcgt
     6001 gagcgcctgc gggaacggct cctcgaagag ggctgagccg aagggctacc ggttctggcc
     6061 gccgaccagg aacagcaggt agaggaagcc cgcgatgatg tggcccgcga tcagataggc
     6121 gaagagcctg atcacaagac cgcgggggaa ccgctcctca tgcgggctgt caccggctga
     6181 gccgcgcggg tccaaggggt cgtgcgacat gtcgtggatc actttccttg ccggtcgggg
     6241 agggggtgca gctccggtgc ctgcagaaga gtgtgcacga acagcagttc cgcaccctcg
     6301 ggagagtccg ccgcgatgcg gtgcggtgtg atcgagtcga agtgcgcgct gtcgccgggg
     6361 gccagttcgt ggacggcgtc cccgagactc aggcgcagcc gtccggcgac gacgtgcagc
     6421 cactcctcgc cggggtgcac ccgcacgagg tcgccctgga cgccgtgagg gacgaacacc
     6481 cgcagggcct gcatcgcccg tcccgggctg cctgcctggt ggtagtccca ggcgccggcc
     6541 ggcacgggct cgcggtggcg tccccggatg accggttcgc gttccggtgg ctgttcaccg
     6601 agcagttcgg ccaccgtcgt accgtagatt cgggcgaggg cgaggagcat cggcagggag
     6661 ggctgccgca gccccgtctc gagccgtgac agatgggccg gcgagaggcc ggcccgccgg
     6721 gccgcggcct cgagggtgag ccctcggcgg cggcgcagct cgcgcagccg gggtgccatc
     6781 tcgggcaggc cctcggccgc cgatgcggct ggggtcgtca tggctccatt gcgccagagg
     6841 attgcccgcg agacaaattt cttgcctcac gggcaaatcc cctgatcaac ggtgggcgac
     6901 cgcctgcttc accagggtct tcccgaagtc ccacatcaga ccgccactgc cgtgggcgtc
     6961 gtccatcaca gccgtgaagg ccgccacgaa gcggtcgacc tcccgctcgc cgatgatcag
     7021 cggtgggatc agcttgatca cctccatgtg gtcgccggag acctgggtga ggatgcggtg
     7081 cttctggagc agcgggacca ccaccatctg cgcgaacaaa cccttgcggg ccgcctgcag
     7141 caccgtccag cggctgcgca gtttgatcga gtccggacgc ccgaactcga tgccgatcat
     7201 cagcccgcgc ccgcggaccg catgcaggag ctcgtaccgg tcgaccaggg ccgccagccg
     7261 ggcgcgcagc aactcaccgg tcaccctcgc gttggccacg atgtgctcgt cctccagcac
     7321 cgacagcacg gcgaggcccg ccgccatcgc ctgggcgcct ccgccgaagc tcgccgagtg
     7381 gaccagcacc cggtccatcg acgagtagac ccgtctgaag atccaatccc ttccgagggt
     7441 ggcgccgacg ggcacatagc cgcccgacag ggccttggcc acacagacga ggtccggctc
     7501 gacaccggcc tcgtactgga acccgtagaa gtcgcccgtg cgccccaggc ctgtctgcac
     7561 ctcgtccacg atcagcagcg ccttgtactt gtgcagcagc tcctgcgcgg cgcgcaggaa
     7621 tcccggcgga gtcgggtaca cacccttgcc ctggatcggt tccacgacga aggccgccac
     7681 gtcaccgcgc acgagttcac gctcgagcgc ggcgagatcg cccatcgcga tcgcggtgtc
     7741 gggcagcagc ggggcgaacc cctcacggaa gccggcctcg ccgttgaccg agagcgcccc
     7801 cgccgtcagc ccgtggaagg cgtgcgtgca gtacacgacg cgcggccggc ccgtcgcgta
     7861 cctggcgaat ttcagcgccg cctccaccgc ctcggccccg ctgttgccga agtacacccg
     7921 ctccaggtgc ggggtatgag tcagcagctt ctccgccagc aggccgggca gcggctggca
     7981 gtcgaagcgg gtgagatcgg cgagcgagga gtcgagcacg tcgtgcaggg ccttgcgtac
     8041 gaccgggtgg tgacggccca ggcccatcac cccgaagccc gccagcatgt cgaggtagtc
     8101 gttgccctcg gtgtcgtaga agtaggcccc ctgggccctc tcgtagatct tgtcgaagcc
     8161 gatcgtgcgc agcatgcgag gcagttggtg gttgaggtac cgggcgtgca gctcgtagcg
     8221 ctcaccgccg cgccgcgcca gcaggtccgc aagatcgaag cccttgggct gctcggtcat
     8281 tcctcggctc tcctgatcag atcgcctgcc gttgcaggac gctcaccggc cgcccgagag
     8341 cgtctcgcgg gcggcacgga gggactcttt cagcgagccc atggtggcga gcacggcggt
     8401 gggttcgtaa ccgcagtgag ccatgcagtt ggcacagcgc gggtcctttc cacggccgta
     8461 cttgtcccag tcggtctcct cgacgagctc ccggtacgtg gggacatagc cgtcactcat
     8521 cagatagcag ggacgctgcc agccgaagag agagtagttg gggatcgccc aggcggtgca
     8581 ggggaagtcg gccttccctt cgaggaagtc gaggaagagc ggagagtggt tgagccgcca
     8641 gcgccgccgg ttgccgccgg cgaaggcctt cctgaacagc tccctcgtct gttcgacacc
     8701 gaggaagtgc tcctggtcgg gggccttctc gtaggcgtac gcgggcgaga tcatcatctc
     8761 gtcgaccttc aggtcgtcgt tgaggtagtt gagcacctcg acgacggtct gcggggtgtc
     8821 ggtgttgaag aaggtcgagt tggtggtgac ccggaagccg cggcgcttgg cctcctcgat
     8881 cgccgcgacc gcctcgtcga acacgccctc cttggcgacc gattcgtcgt gccgctcgcg
     8941 cagcccgtcg atgtgcacgg cgaaggcgaa gtacggggag ggggtgaact tgtcgatctt
     9001 cttgcgcagc agcaatgcat tggtgcagag gaagacgtac ttcctgcggc gcaccaactg
     9061 cctgacgatc tcgtcgatct gggggtgcat cagcggctcg cccccggcga tggaaaccat
     9121 cggggcaccg gactccagca ccgctccgac cgcctgcgcc accggcatcc gctgcttgag
     9181 cacccctgcc ggatgctgga tcttcccaca gccctcgcag gcgagattgc acgcatagag
     9241 cggctcgagc tcgacgatca gagggaactt gtcgcgtctg cggagcttct gttcgaagag
     9301 atacgtaccg accctgatgg tctggcggag cggcatggcc atctggctca cctcctgggg
     9361 agcagcaaag aacggtgcca ttcaaagaaa gcgggcatca cagcacggag aacacggaaa
     9421 gctgatattc cgccacgaag tgttccgata cgcaccagtt cgtgttcggg agcgtccacg
     9481 accacccgga cggccgcaag cgggcgcggt ccggcctcca gggcactgct gagcgtggca
     9541 gcggactcca tgtccgccgc gatcgcgccc gtccccagca gccgtgcgcg ctcatgacct
     9601 ctgacgacgt ggtccacgcc ggtcagcgga ccggtgtgga ccgtgcggcc gggtgcggct
     9661 ctggcgacgg cctccgccag cagctccgtg ttggtgcagg cggtgggcga cccgccgagc
     9721 ctgacctcct ccacgaccac cagatccccc gggtgcatcc cgggggcgag tcccgcacag
     9781 aagccggacg cgacgaccgc cgcctccgcg agcgccgtgg tccggcaggc cacgcgtacg
     9841 gcacgccccg cgttgaccgg ccccatcccc gtacggagaa ccgtcacgtc acccgcggcg
     9901 ccgccacggt caccggcgcg cagggcgaac ttctcgatac cgagcgcgca ggcgatcagc
     9961 agcgggacgg cagagccgga cggcttgctg gagtccgcca tcagcccccc tcgcgggcgc
    10021 ccgagcgggc acccgcgcgg ccgggaagct tctccccgta cacatagcgg ccgagtgcgg
    10081 tgagcgggaa gacctgccgg tacaggtggt agttgatgga gaagtcccag gggaagccgg
    10141 tgccggtgaa gtacggctcg tcccaggagc cgtccggcgc ctgcgtctgc gcgagatggg
    10201 cgacgccccg ttcgacggcc ttgctctccc gctcccccgc cgccagcagc gcgagcagcg
    10261 cccagccggt ctgggatgcc gtggacgcgc catggccgat cgacctctct tcccggtagg
    10321 agcgcaggtc ctcgccccag ccgccgtcct cgttctgcac ggattccagc caggcgacgg
    10381 cacgccggat cgccgggtgg gagccgggca gccccgccgc ggtcagcgcc ggcaccacag
    10441 cgcccgtccc gtatacgtag ttgacgcccc agcggccgaa ccaggctccg ttcgcctcct
    10501 gatgggcgag cagccaccgg acgccccgcc gggtgcgcgg gtcgtgggcc atgccctcgt
    10561 gggccagtat ctcgacgaca tgcgcggtga cgtccgcgga cggtgggtcg atgacctccc
    10621 cgaagtcgca gaacggaagc cggttcggga acgggctggt gttgtccgcg tcgaacgccc
    10681 cccatgcgcc gtcgcgggac tgcatgccga ggttccagcg ggtgccgcgc gccacggcgg
    10741 cgtcgacccg ctccgggtcc gggtgcttca cccgccgcag ggcgaggacg acctcggccg
    10801 tgtcgtcgat gtccgggtag ttgtcgttgt ggaactcgaa cgcccagccg ccggggccga
    10861 gcccgggcct gcgcaccgac cagtcgccgg gccgtacgac ctgctcgctg agcatccagt
    10921 cggccgcttt caccagcgcc ggatggtcgg cgggcagtcc ggcgtcggcg agggcgatgg
    10981 tcgccaggca ggtgtcccag accggggact gacaggcctc gatcatccgc acggggaggc
    11041 cttcctcctc gtggtggacg gcgaagcggt ccagcgactc gagtcccgcc cgcatgacgg
    11101 ggtgctcgag gtcgtagccg agcaggtgca gggcgatcac cgagtacacg gccgggggct
    11161 ggatgccacc ccagcagccg tcgttctcct ggcgctcgat gatccagcgg gccgccgcgt
    11221 tcatggcggc ccggcgcagc cggcgcgggg cgaccttgtg gtaggcgtgc agcgccttgt
    11281 cggcgcgctg gaagaagccg tcccaactcg ccgcaggcgc gaggcgcttg cccgggttgg
    11341 gcagggcgcg gtcggtgtgc agctcgtcca gggcgaacgg ggcgggccgt acggggcgct
    11401 tcgcggagac gacggtgagc ggcacgatgg tctgccgcgc ccagcagccg aagtcgtaga
    11461 tgttcagggg gaaccacttc ggcaggaaga tcagctcggg cggcagctcg ggcaggtcct
    11521 cccacttcca ccagccgaac agcgccagcc agatccgggt gaagacccgg ctcgcggcga
    11581 tgccgccccg gctgcgcacc catgaggcgg cgcgctgcat gtgcgggtcg tccggccggt
    11641 cgccggccag ccgcagggcg acataggcct cgacggtggt ggagagctca ccgggcccgc
    11701 cgtagaaggt ggcccaggtg ccgtcgtccc gctgctgccc acggatgaag cgggcggacg
    11761 cctcgacggt cgccggatcc tggatgccga ggaactgccg cagcagcagg tcctccgcgt
    11821 ccatggtcac attggtctcg aggtcgccct tccaccagcc ctcggcgtcc tggcgtgcga
    11881 gcagatgctc cacggcgcgt tccgcggccc gggcggccgc ttcccgtagg tctgtgcccg
    11941 gctctgtggt ccgggcggca ctcgtagaag ttgtttcgcc ggcagtggcg gcgccgcccc
    12001 tcaggggccc gctgcttccg tcggtcgtcg ctgtcatgtt ctccccttcg ttgcagtggt
    12061 ctctgctgag ccggggtctg acgtcggccg gtgacacgat ggtcaccggc cggcgacgcg
    12121 cttcatatgg tgcggctgtt gctccggtcg gtcctggacc gggtgggaca ctgcctggcg
    12181 gcggcagggg cggtaacgat ggcgatcatc tctttcgtac gacgacgaag tccgcaagcg
    12241 cgacgagctg ggcgcgaacc cgttccggca tgtcgacgcc gctgagggcc tcgatcgcga
    12301 cggcgtgctg gcggcgggcc tcctgggagg tccactcccg gccgccggcc tcctcgatca
    12361 gagccgcccg ggtggcgaac tcctcctcgg agaagctgtc gacgtcgttg ctcttggcgt
    12421 cggcggcgag cagttcgccg agccgctcgg aggccgggcc gccggcggcg agggccgcga
    12481 cgaccggcag ggacttcttg cgctggcgca ggtcgctcca ggtctgcttg ccggtggcga
    12541 ccggatcgcc ccagatgccg agcaggtcgt cgacggcctg gaaggcgagg ccgaggtggt
    12601 agccgtacga ctccagcgtg tccgccgtgc ggtcgtcggc gccgccgagc acggcgccga
    12661 tcgagacggc gcaggccagc agggcgccgg tcttgttgcc ctccatctcc aggcactcct
    12721 cgacggtgac ccgctcacgg tgctcgtagg agatgtcctg ggcctggccg tcgatgagct
    12781 tgcgcgtggc cgtggtgagc cggcgggtcg cccgcccggc ctccacggtg ccgatctcca
    12841 gcagcacctc gttcgcgagg gcgaacagcg cgtcgccgac gaggatcgcc tgtgcgggcc
    12901 cgtgcacctt ccagacggtg tcgcggtgcc ggcgctgctc gtcaccgtcc atcaggtcgt
    12961 cgtgcagcag cgagaagttg tgcaccagct ccacggcgac cgcccccggg acgccgacct
    13021 cgggcgctgc cccggcggcc tcggcggaca gcagcgccag cgccgggcgt acggccttgc
    13081 cgccgtcgcc gtcggagggc cggccctggg cgtcgatcca gccgaagtgg taggcggcga
    13141 cggtgtccat gggcggcgcg agccggccca cggcggcgcg cagcaccggc gtggacaggg
    13201 tccgtccgcg ctccagcagc gcggagacgt cgacgctctc cgcactctgt gcggtgtcgt
    13261 cagccgggta cgccgagtgc actgtcggca cgcttactcc tctggttcca gtactggtgc
    13321 tcacgccgcc tcctcgagcg gatgttcatg gcggcggccg agcgcggaga gcgcggcacc
    13381 cgcagcgctg aagccgctgc gcacggcgcc ctccatggtc gcgggccagc cggtggcggt
    13441 ccacgcgcca gcaaggtaca ggccgcgggc acgtgtgcgc gcaaccggcc gcagccgtcc
    13501 cacgccgggt gacggtgcga acgttgccgt ccgctcacgg gtgacgaaga agtccctcac
    13561 ctgggcaccg cgagcggcgg gcaacagccg ttccagctcg ggcagatacc gcttccgcag
    13621 cacggacacg ggctcgtcga tctcgtcctg cgcggccgac tgggagaccg cgaggtactg
    13681 gccctccttc gcaccggacg ccgcggtgcg gtcgaacacc cactggacgt gcgtgccgag
    13741 agcggcgaag aacgggcggc gcagcacctt gcggtcgtac agcacatgga cgttgaggat
    13801 cggggcggtg ccgatgtcga gcagccggtc cgggtcctcc agcgcgccgt ccgggagcag
    13861 cgcgtgggcc tcccgctgtg cgacggcgag cacgacaacg tcggcgtgaa gctcctcgcc
    13921 gtccacgacg acctgccagc gtccgtccgc cgaccggttg atctcccgta cccgggtgga
    13981 cagttcggtg cgcactcctg cggagtcgag ggccttgcgg gcgagcgtgt cgtgcagctc
    14041 gccgaggggt acccgggccc agccgatgtc ggcggcgccg ggctccgaga gcagtccggt
    14101 cttgaagacc atcgcggcga ggcccatgga cgcctgcggt gcccgggcgt tgagcgtcgc
    14161 cacgccgacg aggtcccaca gggcggccac ggcgcgcggt gactggccgt ggcggccgag
    14221 ccagcccgcg aagtcgatgc cgtccagcgc cgggtcggcg gggtcgagcc tgccgagcgc
    14281 gagcgcggcg cgcccgacac ccgcccgttc cgcgagggag aggtgcgggt agcgggcgag
    14341 gctcgcgccg aggtgcagcg gtacgggcag cgcgctgcgc cgcagtcggc cgagccgcgg
    14401 gccgcccttg gcggcgacgt cgagcacggg cacgtccagg cggttctgga ccggggcgag
    14461 gtgggcgccg tcgatccggt cgagaaacca gcggtaggcg gtgcagcagc gcaggtggac
    14521 gtgctgcccg ttgtccacgg tgagcgcgcc ccgccggaag gagaaggcga gcccgccgag
    14581 ccgcggccgg ctctccagca gggtgacccc cacaccggcg tcggcgagct gaagcgcggc
    14641 ggtgacgccg gcgattccac cgccgacgac cacggcatgc cgtgcgccca gggtgtcggg
    14701 ggccgtcatg atcgcgcctc cctcgtacgg gccgtcgtcg atctcttcgg gccgggcgcg
    14761 gcgaacggca ggccgacgcg cccgtacccg ccaggtcggc ccggggccgc cgtgcggcgc
    14821 cggctcggca gggtggtgcc ccggtgagca gcgggcgcac ccgtccgggg gatcatcggc
    14881 ggcccccttg ggtctggcgg ccgatgaggc gggcgtcgag gccggagagg ccgcggacgg
    14941 cgacgtatgc cttttcgcgc ccgggcagcg agacccgccc gcggagcacg gcctccggct
    15001 cgcgctcgat gcggtcgagg aggcggcggt agatgccggc catcgccgcg acacacgcgc
    15061 cgctgcgccg gtcgagcatc ggcagcaggc ggtagccctc ggcgaacagg gccctggcgc
    15121 gccggacttc gaagtggacg aggccggtga aatcggcgcc gggccgcggg gtcgtgccgt
    15181 ggaagccttc tgagcaaccg aacttggcga ggtcgtcggc cggcaggtac gtacggccgt
    15241 tggcggcgtc ctcggtcacg tccctgagga tgttggtcag ctgcagcgcg agccccagcg
    15301 tgtcggcgta ctcggcggcg cgctcggatc cgcgcgcgcc gggctgggtg ccgaacacgc
    15361 cgagcgagag cctgccgatc gcgcccgcca cgcaccggca gtagaccttg aggtcgtccc
    15421 acgtctcgta gctctcgccg cggacgtcca tcagcacccc gtcgatgagc tcgtcgaggc
    15481 cgccgagcgg cagggggaag cggcgtgcgg cgtccgagag ggcgacggcg acggggtcgg
    15541 tgtcgtcctc gtcgacggcg ccccgcctga tgcgctcgag cagttcgcgc gttccttcga
    15601 gacggtcctg cttggcctgc ggcttcagct tgccgtcgcc gatgtcgtcg acgcgccgcg
    15661 aaaacgcgta cagcgccgac atggcctggc gcttgtgagt cggcagcagc ctgatgccgt
    15721 aggcgaagtt acgggcctgc tgcccggtga cggcctcgca gtagctgtac gcggcctgca
    15781 ccggcgcggg caccacggtc ggtccctcca tcgtccggct catccctctc tacgcgctcg
    15841 tcgcaagaca gcccctactt cacgcagcag attcgtcctg gttgctctgg gcggcccggg
    15901 cagcacatca tgtccggccg cggcgatcgc ggcgagggcg gcacgcccac cggcgacgaa
    15961 acccgccagc agcagccgca gtctgccctc gacgctgccg accagcggcg tgccctcgtc
    16021 cagcagcgcg cgggcgcgcc gcccctcgtg ggcgaccagg gcccgcaccg acgcgttcgc
    16081 ggtgggcgcg gcgaggtcgg cctcggccac gtggaaacgt ttcatgctct cggccggcag
    16141 atagatccgg tcgcgcgcca ggtcctcggc gacgtcctgg aggtgctcga cgatctgcag
    16201 cccggtgcag atcgcgtcgg agcgtcggac ccgctcgggg gtggtggtgc cggtgatgcc
    16261 gagcaccagg cggcccacgg ggttggcgga cagctcgcag taggcgagga ggtcgtcgta
    16321 cgtctggtag cggcgcacca gctggtcctg ccggttggcg gcgatcagcc cgaggaaggg
    16381 ctcgggcgtg agcgagcagc ggcggaccgt ggggcgcagg gcgtgcagca gcgggtggtg
    16441 cggcgcggcg ccggacgcgt cgaagacccg gcgcaggtcg gcctcgaagg catcgagcag
    16501 ggcgagccgg tcgtcggcca gctccggtgc gacgccgagg tggtgggcgt ccgcgccgcc
    16561 gggcgcgagg tcgccgtcgc cgatgtcgtc gacgaggcgg gcgtagccgt agacggccat
    16621 gaggtcgtcg cgccaggcgc ggggcagaaa gaagggggcg acggggaagt tctcgtcggc
    16681 cgccttgtcg agggtcgcgc gggcggggac cctcgcgccg gtccgcgcgg tgcccgtcac
    16741 tgcgcgctgc caggagcggg gaacggcaca ccgccatgag cggggacggc gaagcactct
    16801 cggagctgga gatttcccgt catggccgtc acgtctcccg ttctacactg cctacccaat
    16861 gcatcccatt tcggacacgc cgccgcatac tgtgcccccc tgtgcgccgc gcggcggcga
    16921 cgggttcggc cggtcggccc acggcttatc acccgacttg ccgcgatcag taccggtaca
    16981 gcttacgttg tgcaacgctc cccgatgccg cagggtgccg cgcacaccgg aacgacgcgg
    17041 caatcgcgtc caacctcctc gcaccgcacg gaacttgacc gtaccttgcc gaaccgtcag
    17101 ctgcccgggc ggtcgcacac gaaggccccc gccgctcagc cgcggcgggg gccctgccgt
    17161 ccgtgcggac cgggactact tgcccgtctc cttctcgtac gccttgatga cctcgtcggt
    17221 cgggccgtcc atcagcagtt cgcccttctc cagccacagg acacggtcgc aggtgtccct
    17281 gatcgacttg ttgctgtggc tgaccaggaa caccgtgccg gcctccttgc ggagctccct
    17341 gatccgctcc tccgagcgga tctggaaccg gcggtcaccc gtggccagtg cctcgtcgat
    17401 catcagcacg tcgtggtcct tcgccgcggc gatggagaag cgcagcctgg ccgccatgcc
    17461 ggaggagtag gtgcgcatcg gcagggtgat gaagtcgccc ttctcgttga tgccggagaa
    17521 gtcgacgatt ccctggtagc gctcgcggat ctcctcgcgc gacatgccca tggccaggcc
    17581 gccgagtatg acgttgcgct cgccggtcag atcgttcatc agcgcggcgt tgacgccgag
    17641 cagggagggc tggccgtcgg tgtagacctt gccgctctcg gccggcagca gaccggcgat
    17701 ggcgcgcagc agggtcgact tgccggagcc gttgctgccg atcaggccga tcgcctcgcc
    17761 gcggtacgcg gtgaagctga cgccccgcac ggcgtggacc ttgcgcaccc cgcgggactc
    17821 gcccttgtcg cggcgcagga tccggctcag cgccgccgtg gcactgcccc ggccgccgcc
    17881 gcccgcgttg acccggtaga cgatgtgcac gtcgtcggcg atgaccgtcg ggacgcgtgc
    17941 tccggccatg ttgtcgttgt tctcagccac ggccgtaccg ctcctcagcc ttccagaagt
    18001 acacgaagcc cgcgaaaccg accaggaccg cccagcccag gcccgcggcc cagacatgcg
    18061 agggcaggtt ctcggagccg tagccgtcga tcagcgcgaa ccggatgagg tccatgtaga
    18121 cggcggccgg gttgtacatg aggacttccg cgatccaggc cggcttgtcg gcgagcatca
    18181 ccgggatgga gaacatcaca ccggacgcgt agagccaggt ccgcatgatg aacggcatca
    18241 gctgcgcgag gtcgggggtc ttcgcaccca gcctggccat gatcatggcg agaccggtgt
    18301 tgaacacgaa ctgcaggacg agcgcgggaa cggccagcag ccaggacagc gcggggtagc
    18361 tgccgaagcc gaccacgatc gccagcagca cgatcatgga gaacagcagt tgctggagct
    18421 gctgcagcgc gaaggagatc ggcagcgagg cccgcgggaa gtgcagggcg cgcaccagcc
    18481 ccagattgcc ggagatcgag cgcacacccg ccatgaccga gctctgggtg aatgtgaagg
    18541 cgaacacacc cgtcaccagg aacgggatgt agacgtccat cggcatgccc cggctggtct
    18601 tcaggatcac tccgaagatc accagataga cggcggcatt cagcagcggg gtcgccacct
    18661 gccagagctg gccgagcttg gcctggctgt actgggcggt cagcttcgcc tgcgagaagg
    18721 caaggatgaa gtggcgccgg ccccacagct gcctgacgta cgagaccagg cccggacggg
    18781 caccgctgac cgacagcccg tactttgcgg cgagctgcga cggagacagc ccgtcgtcgg
    18841 gcgatggtgc ggggctcatc gcgacggcac cgtcatgggt tgtgtcactc acaagttgaa
    18901 actttcgtgt tcaagatgcg cggcaattcg gggcgcggcc tcaccggcct gtcgcccgat
    18961 gctctcagag ccgagcatgt cagatgacag gaggtcggcc cagcctggtg agacgccaca
    19021 ccgtacgcca cttcatcgga cggcgcggtc cgcagggggt tcgccagccc tcggcgaagc
    19081 cgccgaacca cgccttcagc gccgggagcg acgggcgccg cagcagggtg agcagcaccc
    19141 acaccgccag gtagacgggc accagcggca ggggcaggtt gcggcgcgcg acccacaccc
    19201 ggttacgggc caccatccgg tggtagaccg cgtgccggga cgggggcatg gtcgggtgga
    19261 ggagcagcat gtccgcgcgg tactcgatgg accagccggc gtccagcgcc cgccaggcga
    19321 gatccgtctc ctcgtgcgcg tagaagaact cgtccgggag cccgccgacc tcgcccagga
    19381 ccttggtgcg cacggcgttg gcgccgccga ggaaggtggt gacccgcgag gagcgcatcg
    19441 ggtcggaggc gcgcagccgc gggacgtggc ggcgctgggt gagcccggtc tccgggtcgg
    19501 cgatgcggaa gctgacgata ccgagccccg ggtcggcgtc gaaggcctca cggaccagcc
    19561 gggcggtgcc ggtgtcgggc agcagcccgt cgtcgtcgag gaagagcagt acgtcgacgt
    19621 cacggccgcc gggcccgaag gcctcgatcc cgacgttgcg gccgcccggg atgcccaggt
    19681 tctccggcag gtccacggtg cgcacaccct cgggcacgtc gaccacgggg gcgccgttgc
    19741 cgacgacgac cacctggatc gggtcgccgt cctgcttcgc gaccgagtcg agaagtgcgc
    19801 gcagttcgtc gggccgggtc cccatcgtga tgacgacggc gccaagcttc agcggagcgg
    19861 tcatttcagc ctgctcgacg ccaggacgga gaccaggtgc agcagcgtct ggagcagcgc
    19921 gataccggcc agcacggcca cgccgaggcg ggagaagaac aggtcgccac ggacctggtc
    19981 cagcacggcc agcagcagga tgaggaggga ggcctcgatg ccgaggacca gccggtggaa
    20041 cttcagtgcg gcagcggccc ggcgggcgag ggccaccccc gaggagcgcg gctcggccgc
    20101 cgcctccttc accggcggca gcccgccctg gtggcgggcg acaccgacca ggtcggtctc
    20161 ggccttgatc aggatcgcgc cgagcgcggc gagggtgccg aggaaggccc acagccagtc
    20221 gatccgcccg ctgccccaca gatcggcggc gcgcagtccg aagccgacca ggacggcggc
    20281 gtcgcacaga taggcgccga ccctgtccag gtacaccccg gagagcgaga actgctgctt
    20341 ccagcgggcg atctccccgt cgacgcagtc gagcagcaga tagagctgta ccgccaccac
    20401 accgaggacg gctccccata tgccgggcac cagcagggcc ggagcggcca ggacaccggc
    20461 gagggtcatc agataggtca gctggttcgg cgtgatcgcg gtgttcacca ggtaccggtc
    20521 gacgcgaagc gagatctccc gcatgtacag gcgcccggcc cagtgctcac cgctgcgccg
    20581 gtccttcaca cccgcggggt gaacgaccgg gcggagttca gctactgatg gtcttggcat
    20641 agtcggcgta cgcgtccctg atctggtcgt gggtgaggtc gaggtgctca aggatggtga
    20701 agcggccggg gcgggtctgc ggcgcgtact cgacagcacg cacgaactcg tccggggaga
    20761 acccgatctc gtcgggcgtg acgggcagcc cgtgccgccg cagcacctcg gcgaacaggc
    20821 ccgcctgttc gtgggcgccg cgcaggtgca tcgcgaaggc ggcgccgagg ccgcactgct
    20881 cgccgtggct cgcggcgcgc ttggggtaca gcaggtcgaa ggcgtggctg atctcgtggc
    20941 aggcgccgga cgagggccgg gagtcgccgc tgatcgacat ggcgatcccg gacagcacca
    21001 gggcctcggc gaggacggtg aggaactcgt cgtcgccgac gcccccgggg tgacgcagca
    21061 cggactcacc ggcggtacgg gccatggcgg ccgccaggcc gtcgacgttc tcgcccttga
    21121 tccggtggga gagctcccag tcggcgatcg ccgagatgtt ggagatcgcg tcgccgatgc
    21181 cggagcggac gaaacgaacc ggcgcctccc ggaccacgtc gaggtcgatg accatggcga
    21241 tcggggaggg gacgccgtag gagccgcggc cgttgtcgtt gtccaggatg gagatcggcg
    21301 agcacaggcc gtcgtgggcc aggttggtgg cgacggccac gagcgggagg cccacccggg
    21361 ccgcggcgta cttggccacg tcgatgatct tgccgccccc gaggccgacg accgcgtcgt
    21421 agcggttgcc cttcatgtcg tcggcgagct tgaccgccga gtcgatggtg ccgtcgcaga
    21481 cctcgtacca gtcggcgccg gtcagggccg gggcgacttt ctcgcgcagc ttctggccgg
    21541 aaccgccgct gatcgcgaag gccagcctgc cggaggacga gatccgctgg tcggcgagga
    21601 tgccggccag gtcgtcgagg gcacccgcgc ggatgtcgac gacgaccggt gaggggatga
    21661 gccgggtcag tactggcacg cgatctcacg gcccttcgcg aggtcgtcgt ggttgtcgat
    21721 ttcgacccac ttgacgtcgc cgatgggcgc cacgtcgacc gtgaagccac ggttcacgag
    21781 ctcctggtag ccgtcctcgt agtagaggtc ggggtcccgt tcgaaggtgg ccctgagcgc
    21841 gtcggcgagg tcggcggccg cgtcgggctc gatgagcgtg acaccgatgt actcgccggt
    21901 ggcggtggcc gggtccatca gcttggtgat ccgctggacg cccttgccct cggcggtgat
    21961 gaccttcatc tcctcgtcgg cgaggtgctt caccgtgtcg agggcaagga tgatcttctg
    22021 gccgttgccg cgggcggcga gcagcgtctg ctcgacggag acggggtgga cggtgtcgcc
    22081 gttggcgagg atcacgccct cggcgatgac gtcacgggcg caccacaggg agtaggcgtt
    22141 gttccactcc tccgccttgt cgttgtcgac gagggtgagc ttcagcccgt acttcgcctc
    22201 cagcgccgcc ctgcgctcgt acacggcctc cttgcggtag ccgacgacga tcgcggcctc
    22261 ggtcagcccg atctccgcga agttgcccag ggtcagatcc aggacggtcg tttcgccgtc
    22321 caccggcacg agggccttcg ggagggtgtc cgtgtaggga cgcagacgcc gtccggcacc
    22381 ggctgccagt acgaggccga tcatgcgggt tctccttcgt catgtacggc gggtgcttgt
    22441 gaggacaccc agaaacggat gctctccacc agcaccacga gggccacggc cacagcgagg
    22501 accgtcagcg cgatggtgaa gtctgtggcg cccggcagga gggcgagcag cgtgaccgcg
    22561 aggacccgcc cttcgtgccc gccgatcgtc cgcaccagcc agtgcggggg cgcgccggtg
    22621 ccaccgcgga tgcggtacac cgtgtcgtag tgatggtagg cgacagccgc aatcaggccg
    22681 aaagccgcgg gcaatgcccc gttcaccccc gcgtgggcgg cgaggacgag gatcgtgccg
    22741 tactcggcgg cccggaagac gggggggacg agccagtcga gggcgccctt gagggggcgg
    22801 gcgacggcga ttcccgaggt ggccgcgtac ccgagggcgg cgacgaccgt ccagacgctg
    22861 ccgaatccgg tgaacgcggc ggtcgccacc agcgctgccg caccggcgac ggccgccgcg
    22921 agcggtgcga ttcccggcag gctccgcgcg gtgcgcgcgg tgacgcgggc cacggcctcg
    22981 gccgccggtc cggagtccgc gaggtcggcg agcgcctggg ccgcgcggtc ggtccggtgc
    23041 gccttgcgcg tcagggagcg caggacgcgg ccggccgtgg tgtagcaggc ggcgagcgcg
    23101 cagccgacga gcagggcgca gaagacgatg cgcggggtgg tcacggcggt gagcacggcg
    23161 atcatcgccc agcgttcacc gatcgggagc actatcatcc ggcgcagcca gaccgtccaa
    23221 ccgacgctgt cgagtttgct ggacagggct gcggtgggac tcgtgttcgc ggtcgcgtcg
    23281 tggttcgcct cgttgaagga gaagtccacg acgtgccggc aggtctgcag caccatcgcg
    23341 cccagcgcga gcgcccatac gtcgtccccg ccgcgggccg cgccgagcgc gaggcccgcg
    23401 tagtaggcgt actccttggc ccggtcgaag gtcgcgtcga gccaggcgcc catcgtcgag
    23461 tactgcaggg agtagcgggc gagctgcccg tcggtgcagt ccaggacgaa cgagaacagc
    23521 aggagcaggc cggccgcgac gaagccggcg cgggtgccgg tggccgcgca gcccgccgcg
    23581 atcagcgcgg tgagcaggga cgcggtggtg acctggttcg gagtcagtcc ccggcgggcg
    23641 caccagcggg cgatgtaacg cgagtacggg ctgatgcaga aggtggtgaa gaagccgtcg
    23701 cgcgccttca cggctgaacg cagccgtacc gcctcgtcgt cgaccgcctc gacggcggcg
    23761 cgcacccggt gccgctccgc cgcctccgag ggcacggcgg cgatcaggga gcccagttcg
    23821 gggtggtgca cggccacacc ctgcgcctcg agctcggcga tgacgctgtc gacgacgccg
    23881 tcaccggcca cggcgcccgc tcccgcgggc acggtggcgg agaccgcccg taccgcgccc
    23941 gccagcgcga cacgaccggc cggctgggcg gtgagcgctc cggtgaccga ggcggcgggg
    24001 aagcgcgggt cggtgagcgc cagccgcagg gcgtgcacat ggcccacgaa gcgcggatcg
    24061 accagggcga cccgctcggc agcgggcacg gccgaaatca gtgcggcggt gtgctcgggg
    24121 ccgttggcga cccgcacgtc gaagcccagc gaccgcagat cgccctcgag cgacgatccg
    24181 ggtgcgggcg gaccggtgag gatggcggtc gacagacgaa ctcactcctt ggagctgacg
    24241 gtgctggtgc acggcggccc tgtccggccc ggcggtcggg cggcggcacg tcggctgagg
    24301 ctatcggatg aacggaagcc cgagttcacc ggccgttcac gccctggcgg cccgccgaga
    24361 tcatcattgt cgatcgatgc cccgccctcc aaaccgcggg ttgcccgagg cgccgggaag
    24421 cacggtgggg cggtcgcaac cggcccgggc cgaggcgggg caccccatag ggtggccgtc
    24481 atgacttggc tgatcacagg tggagcggga tacatcgggg cgcatgtggc gcacgccatg
    24541 acagctgccg gtgaacgggt cgtcgtgctc gacgacctgt cctcggggat tcccgggcgg
    24601 ctgccggccg gcgtcccact ggtgcgcgga tctgtgctcg accgcgacgc ggtggaccgc
    24661 gtactcgccg ggcacgccgt cacgggtgtg gtgcacctcg ccgcgaagaa gcaggtcggc
    24721 gagtcggtgg aacagccgct caggtactac cgggagaacg tgtacgggct caccgtgctg
    24781 ctggaggccg tcgtcgccgc cggtgtgcag cggttcctgt tctcgtcctc cgccgccgtg
    24841 tacggggtgc cggacacgga cctcgtgtcg gagtcggccg cgtgcgagcc gatcaacccg
    24901 tacggggaga cgaagctcac gggcgagtgg ctggtgcggg ccgccgggcg ggcgcacggc
    24961 ctgtcgaccg cctgtctgcg gtacttcaac gtcgcgggtg cggccgctcc cgagctggcg
    25021 gacacggggg tgttcaacat catcccgatg ttcttcgacc ggatcacccg tggggaggcg
    25081 ccgcggatct tcggcgcgga ctaccccacc ccggacggga cctgcatccg cgactacatc
    25141 catgtcgccg atctcgccga cgcgcacctg gcggtggcgc gacggctcgc cgggaccgag
    25201 gccggcaagg acctcaccgt caacatcggc cgcggggtcg gcgtctcggt ccgggagctc
    25261 gcccgcgtgg tgggcgaggt gaccggccgc cacttcgatc cggtggtcga gccgcggcgg
    25321 gccggagacg ccgcgaaggc cgtcgcatcg gtcgagctga tcgccgagga actcgggtgg
    25381 accgcttcgt acggggtacg cgacatggtc gcgtccgcct gggcaggctg gtcggccagg
    25441 cacccggaaa cggctgctca ctgatcgtcc cgaggctctg acctgcgagc atttccgcag
    25501 gtcagagcat atgacaacgg tgttcagtgc cgtgttgccc gatacccccc gcccgtagtt
    25561 gactggggct cgaccgagcg atgcagcgga tgcgggctga cggaagggca ccgacatggg
    25621 ggctgggcac gaccacgggc acgggcacgg cggccccccg ccgacgggca ccgccgccgc
    25681 cctctacaag ggccggctga ggatcgccct cgcgatcacg ctgggcgtga tggtgctgga
    25741 gatcatcggt ggcgtgctgt cgggctcact ggccctgatc gcggacgccg cccatatggc
    25801 gacggacgcg gtggggctcg ccatggcgct gctggcgatc cacttcgcaa accggcccgc
    25861 cgggcagaac cgcacgttcg gcttcgcccg tgccgagatc ctcgcggcgc tcgccaactg
    25921 tctgctgctc atcggtgtgg gcggcttcct gctcttcgag gcggtggagc gtttcatcga
    25981 gcccgcgcag acccggggcg gtctgaccgt cgttttcgca ctcgtcggcc tcgtggcaaa
    26041 catggtctcg ctgaccctgc tgatgcgggg acagaaggag agcctcaacg tgcggggcgc
    26101 gtacctggag gtgctggcgg acgcgctcgg ttcggtgacc gtcctgatct cggcggggat
    26161 catcctgggg accggctggc agtacgccga cccgatcgcc tccctggcca tcgggctgat
    26221 gatcgtgccg cgcacctggc ggctgctgcg ggagacgctg aacgtactgc tggaggcggc
    26281 cccccagggc gtcgacatgg gtgacgtccg tgcccacata ttggcgctgc cgggtgtgga
    26341 ggacgtgcac gatctgcacg cctggacgat cacgtccggg atgccggtgc tctccgcgca
    26401 cgtggtcgtg agccaggacg tgctggactc ggtgggacac gagaagatgc tgcacgacct
    26461 gcagggctgt ctcggtgcgc acttcgacgt cgagcactgc accttccagc tggagcccgt
    26521 gggccacgcg gagcacgagg cgaagctctg tcactgacgg accccgtcac cgagcggccc
    26581 ggccgctgct agggttcttc gcgggggcaa ccacgtccca ccgcccttga gaggagctga
    26641 ggttgatgac cgtcgcgatg gacgctgccc ggcgcagcgc ccggtccttc ctcaacctcc
    26701 gggcctccgt ccgaccctga cccgaccccg gtccggtttt
//
