LOCUS       NZ_BMVW01000034        21517 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces poonensis strain JCM 4815 sequence34, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVW01000034
VERSION     NZ_BMVW01000034.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces poonensis
  ORGANISM  Streptomyces poonensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 21517)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 137X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650915.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:27:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,577
            CDSs (total)                      :: 7,501
            Genes (coding)                    :: 7,228
            CDSs (with protein)               :: 7,228
            Genes (RNA)                       :: 76
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 273
            CDSs (without protein)            :: 273
            Pseudo Genes (ambiguous residues) :: 0 of 273
            Pseudo Genes (frameshifted)       :: 96 of 273
            Pseudo Genes (incomplete)         :: 224 of 273
            Pseudo Genes (internal stop)      :: 19 of 273
            Pseudo Genes (multiple problems)  :: 60 of 273
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:46:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 21517
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVW01000034.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21517
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     gene            <1..3363
                     /locus_tag="IE242_RS37155"
     CDS             <1..3363
                     /NRPS_PKS="Domain: PKS_AT (0-157). E-value: 3.7e-49. Score:
                     159.6. Matches aSDomain:
                     nrpspksdomains_IE242_RS37155_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (226-392). E-value: 7.4e-62.
                     Score: 200.5. Matches aSDomain:
                     nrpspksdomains_IE242_RS37155_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (682-860). E-value: 2e-58. Score:
                     189.3. Matches aSDomain:
                     nrpspksdomains_IE242_RS37155_PKS_KR.1"
                     /NRPS_PKS="Domain: ACP (963-1033). E-value: 1.1e-33. Score:
                     107.4. Matches aSDomain:
                     nrpspksdomains_IE242_RS37155_ACP.1"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (1046-1119). E-value:
                     5.3e-13. Score: 41.6. Matches aSDomain:
                     nrpspksdomains_IE242_RS37155_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981856.1"
                     /locus_tag="IE242_RS37155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_189867487.1"
                     /sec_met_domain="PKS_AT (E-value: 2.4e-50, bitscore: 159.6,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.2e-62, bitscore:
                     199.1, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.6e-18, bitscore:
                     55.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="SEEEVLPHLAEGVGVAAINGPRSVVVSGAEAAVLAIGEVFREQGR
                     KTSRLKVSHAFHSPLMEPMLAEFGEVVAGLSFEQPRIPVVSNLTGRLVEAYTPEYWVEH
                     VREAVRFADGIATLHELGVGTFVEIGPGGVLSALAQGCFDGDADVVTVPVLRADRPEEQ
                     AVVTALADLHVHGVSPDWQVLFPGARRVDLPTYAFQRERYWLDAPEEFTGGAAATGLGL
                     SAAEHPLAGAAVALPGAGGFLVTGRLSLRTHPWLADHTVMGNVLLPGTALVELAVRAAD
                     EAGCAQVEDLTLEAPLIVPDRGGVAVQVWVGPEEEPGRRALSVHSRPEDAPDVAPWVRH
                     AVGFLTGELPEPPHGTDLGVWPPAGAEAVDLEGYYEGLDALGLGYGPVFRGLRSVWRSG
                     DDVLAEVVLPEDVEAGAFAVHPALLDAALHAIGAGGLVPVADGPLLPFAWSEVGVRAAG
                     ATVLRVKASRTGTDTVSLTVADTSGGLVATTGSLALRPVTREQLDAAGGSGSRAGDSLF
                     GLAWQPLALTRAGAALDVRSYPSASAVFAEPDLPDVAVLTVPPCPDGPDTEVADRVHGI
                     ACEVLELVQWWSAREGAGRLALVTSAGDLAHAAVWGLVRSAQSENPDRFVLVEAEEVGE
                     AVRVLPAVLASGEPQFALRGGEVFVPRLVKTPTAAPGGDDGLPDLIDGTVLVTGASGAL
                     GALVARHLVSEHKARRLLLVSRRGADAPGAAELGAELAAEGADITWAACDVADREAVAE
                     LLTGLGEHPLSAVVHTAGVLDDGVVASVTPERLRGVFRPKVDAVLNLHECTHGMDLAAF
                     VVFSSVAGLVGSAGQASYAAANSFLDAFSAHRRRAGLPATSLAWGVWEQSGAMTDGLAE
                     ADRARMARSGVLPLPPEEGLRLFDAALVSDEAVLAPVRIDTGALRAGEAPPVLRSLVPA
                     MTVRRTAQTAAVSAPSLAERLDGLPEGEREKTVLDLVRAEVAAVLGHASDRTVRPEHAF
                     QDLGFDSLTAVELRNRLNRATGLRLPATLVFDHPTPALLARHVFTETAAAAPALVDSLL
                     ADLDRVEQELATKLGEGEARDRITSKLQKLLAITGGFGTVPARESADTGESDLESATDD
                     EVFDLLGKEFGIS"
     source          1..21517
                     /culture_collection="JCM:4815"
                     /db_xref="taxon:68255"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces poonensis"
                     /strain="JCM 4815"
                     /submitter_seqid="sequence34"
                     /type_material="type strain of Streptomyces poonensis"
     cand_cluster    1..21517
                     /SMILES="C=CC=CC([*])C(-O)C=CC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21517
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[3434:19725](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3435..19725
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     aSDomain        4..474
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: False, scaffold matched
                     GHGE: False"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37155_PKS_AT.1"
                     /evalue="3.70E-49"
                     /label="IE242_RS37155_PKS_AT.1"
                     /locus_tag="IE242_RS37155"
                     /protein_end="157"
                     /protein_start="0"
                     /score="159.6"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: (unknown)"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="SEEEVLPHLAEGVGVAAINGPRSVVVSGAEAAVLAIGEVFREQGR
                     KTSRLKVSHAFHSPLMEPMLAEFGEVVAGLSFEQPRIPVVSNLTGRLVEAYTPEYWVEH
                     VREAVRFADGIATLHELGVGTFVEIGPGGVLSALAQGCFDGDADVVTVPVLRA"
     aSModule        4..3102
                     /complete
                     /domains="nrpspksdomains_IE242_RS37155_PKS_AT.1"
                     /domains="nrpspksdomains_IE242_RS37155_PKS_DH.1"
                     /domains="nrpspksdomains_IE242_RS37155_PKS_KR.1"
                     /domains="nrpspksdomains_IE242_RS37155_ACP.1"
                     /locus_tags="IE242_RS37155"
                     /monomer_pairings="mal -> ccmal"
                     /starter_module
                     /tool="antismash"
                     /type="pks"
     CDS_motif       49..87
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37155_0001"
                     /evalue="6.70E-05"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE242_RS37155"
                     /protein_end="28"
                     /protein_start="15"
                     /score="16.0"
                     /tool="antismash"
                     /translation="AAINGPRSVVVSG"
     CDS_motif       301..336
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37155_0002"
                     /evalue="7.50E-05"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="IE242_RS37155"
                     /protein_end="111"
                     /protein_start="99"
                     /score="16.1"
                     /tool="antismash"
                     /translation="YWVEHVREAVRF"
     aSDomain        682..1179
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37155_PKS_DH.1"
                     /evalue="7.40E-62"
                     /label="IE242_RS37155_PKS_DH.1"
                     /locus_tag="IE242_RS37155"
                     /protein_end="392"
                     /protein_start="226"
                     /score="200.5"
                     /tool="antismash"
                     /translation="HPLAGAAVALPGAGGFLVTGRLSLRTHPWLADHTVMGNVLLPGTA
                     LVELAVRAADEAGCAQVEDLTLEAPLIVPDRGGVAVQVWVGPEEEPGRRALSVHSRPED
                     APDVAPWVRHAVGFLTGELPEPPHGTDLGVWPPAGAEAVDLEGYYEGLDALGLGYGPVF
                     RGL"
     CDS_motif       766..843
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37155_0003"
                     /evalue="2.00E-09"
                     /label="PKSI-DH_m2"
                     /locus_tag="IE242_RS37155"
                     /protein_end="280"
                     /protein_start="254"
                     /score="29.9"
                     /tool="antismash"
                     /translation="WLADHTVMGNVLLPGTALVELAVRAA"
     aSDomain        2050..2583
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37155_PKS_KR.1"
                     /evalue="2.00E-58"
                     /label="IE242_RS37155_PKS_KR.1"
                     /locus_tag="IE242_RS37155"
                     /protein_end="860"
                     /protein_start="682"
                     /score="189.3"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GTVLVTGASGALGALVARHLVSEHKARRLLLVSRRGADAPGAAEL
                     GAELAAEGADITWAACDVADREAVAELLTGLGEHPLSAVVHTAGVLDDGVVASVTPERL
                     RGVFRPKVDAVLNLHECTHGMDLAAFVVFSSVAGLVGSAGQASYAAANSFLDAFSAHRR
                     RAGLPATSLAWGVWE"
     CDS_motif       2053..2154
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37155_0004"
                     /evalue="7.10E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE242_RS37155"
                     /protein_end="717"
                     /protein_start="683"
                     /score="28.3"
                     /tool="antismash"
                     /translation="TVLVTGASGALGALVARHLVSEHKARRLLLVSRR"
     CDS_motif       2431..2538
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37155_0005"
                     /evalue="7.20E-18"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE242_RS37155"
                     /protein_end="845"
                     /protein_start="809"
                     /score="57.1"
                     /tool="antismash"
                     /translation="AAFVVFSSVAGLVGSAGQASYAAANSFLDAFSAHRR"
     aSDomain        2893..3102
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37155_ACP.1"
                     /evalue="1.10E-33"
                     /label="IE242_RS37155_ACP.1"
                     /locus_tag="IE242_RS37155"
                     /protein_end="1033"
                     /protein_start="963"
                     /score="107.4"
                     /tool="antismash"
                     /translation="LDLVRAEVAAVLGHASDRTVRPEHAFQDLGFDSLTAVELRNRLNR
                     ATGLRLPATLVFDHPTPALLARHVF"
     aSDomain        3142..3360
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37155_PKS_Docking_Cterm.
                     1"
                     /evalue="5.30E-13"
                     /label="IE242_RS37155_PKS_Docking_Cterm.1"
                     /locus_tag="IE242_RS37155"
                     /protein_end="1119"
                     /protein_start="1046"
                     /score="41.6"
                     /tool="antismash"
                     /translation="LLADLDRVEQELATKLGEGEARDRITSKLQKLLAITGGFGTVPAR
                     ESADTGESDLESATDDEVFDLLGKEFGI"
     gene            3435..14156
                     /locus_tag="IE242_RS37160"
                     /old_locus_tag="GCM10010365_76120"
     CDS             3435..14156
                     /EC_number="2.3.1.-"
                     /EC_number="6.4.-.-"
                     /GO_component="GO:0034081 - polyketide synthase complex
                     [Evidence IEA]"
                     /GO_process="GO:0030639 - polyketide biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (3-31). E-value:
                     7.4e-13. Score: 39.8. Matches aSDomain:
                     nrpspksdomains_IE242_RS37160_PKS_Docking_Nterm.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (35-461). E-value:
                     1.8e-186. Score: 612.1. Matches aSDomain:
                     nrpspksdomains_IE242_RS37160_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (586-863). E-value: 3.7e-103.
                     Score: 336.9. Matches aSDomain:
                     nrpspksdomains_IE242_RS37160_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (931-1099). E-value: 4.5e-65.
                     Score: 211.0. Matches aSDomain:
                     nrpspksdomains_IE242_RS37160_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (1403-1576). E-value: 6.1e-54.
                     Score: 174.7. Matches aSDomain:
                     nrpspksdomains_IE242_RS37160_PKS_KR.1"
                     /NRPS_PKS="Domain: ACP (1679-1749). E-value: 2.1e-32.
                     Score: 103.2. Matches aSDomain:
                     nrpspksdomains_IE242_RS37160_ACP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (1776-2202). E-value:
                     7.8e-190. Score: 623.2. Matches aSDomain:
                     nrpspksdomains_IE242_RS37160_PKS_KS.2"
                     /NRPS_PKS="Domain: PKS_AT (2314-2609). E-value: 3.4e-104.
                     Score: 340.3. Matches aSDomain:
                     nrpspksdomains_IE242_RS37160_PKS_AT.2"
                     /NRPS_PKS="Domain: PKS_DH (2675-2835). E-value: 2.8e-64.
                     Score: 208.4. Matches aSDomain:
                     nrpspksdomains_IE242_RS37160_PKS_DH.2"
                     /NRPS_PKS="Domain: PKS_KR (3139-3312). E-value: 5.6e-52.
                     Score: 168.3. Matches aSDomain:
                     nrpspksdomains_IE242_RS37160_PKS_KR.2"
                     /NRPS_PKS="Domain: PKS_PP (3401-3484). E-value: 3.9e-33.
                     Score: 105.6. Matches aSDomain:
                     nrpspksdomains_IE242_RS37160_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (3494-3572). E-value:
                     6.3e-13. Score: 41.4. Matches aSDomain:
                     nrpspksdomains_IE242_RS37160_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981855.1"
                     /locus_tag="IE242_RS37160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_76120"
                     /product="type I polyketide synthase"
                     /protein_id="WP_189867489.1"
                     /sec_met_domain="adh_short (E-value: 2.5e-59, bitscore:
                     188.3, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 1e-239, bitscore: 783.5,
                     seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 9.3e-99, bitscore:
                     318.1, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2.3e-105, bitscore:
                     340.3, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.5e-18, bitscore:
                     52.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANEDKLRYFLKRVTADLQETRRRLRDHEDAAGEPVAIIGMSCRY
                     PGGVDSPEDLWRLVAGGRDAVSEFPTDRGWDLDALYDPDPESRGTSYAREGAFLQDPAR
                     FDASLFGISPREALAMDPQQRLLLETSWELFERAGIDAASLAGSRTGVFTGVMNHEFLA
                     TLQNAPEDLEGYLGTGTSGSVASGRVAYTFGLEGPAVTVDTACSSSLVALHLAVQSLRS
                     GECSLAVAGGVTAMVGPATFVGFSRQRGLAPDGRCKAFAAGADGTGWGEGAGLLLVERL
                     SDARRNGHDILAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALSAARLTAAQVDVVEA
                     HGTGTRLGDPIEAQALLATYGQARTEDKPLLLGSIKSNIGHTQAAAGVAGVIKMVMAMR
                     NGELPRTLHVDAPSPHVDWSAGAVRLLTEHTPWPASDEPRRAGISSFGISGTNAHTIIE
                     EAPSADAPALDAGEEPAEPAEGEGNTEALVPEAARPAEGGPVPWVVSGHTEEALRAQAE
                     RLLSRTESEVSPYDVAFSLATTRTALEHRAVVQGGTPAELAEGLRAVASGSPAPGVARG
                     RSGSGGRVGFLFSGQGSQRPGMGRELYAAHPAFAAAYDEVCSHLGAVVDVDSEELHRTG
                     AAQPALFAVEVALFRLLESWGVRPDYVAGHSVGEIAAAHAAGVLSLEDAAKLVSARAAL
                     MQALPEGGAMVAVQATEDEVLPHLSDGVGVAAVNGPRSVVLSGAEAPVLEIAEIFGRQG
                     RKTSRLKVSHAFHSPLMEPMLAEFGEVVAGLAHEQPRIPVVSTLTGRPAEPYTPEYWVR
                     HVRETVRFADGARTLHELGVTTFVEIGPGGVLSGLTQGCLDEDVVTVPALRADRPERDA
                     LVAAVAELHAHGVSPDWHAFFPGARRVELPTYAFQYDRYWLDAAPATSGDVRAAGLGAA
                     DHPLLGAAVSLAGGDERLLTGRLSLRTHPWLSDHAVLGTVLLPGTAFVELAVRAADEAG
                     CDLLEDLTLEAPLVIPEQGGVAVQVWVGAADDSGRRPLTVHSRPEEDAHLPWVRHATGS
                     VAEATAETGAGAAGSTLATWPPAGAEPIALDGFHDRLAALGLSYGPTFRGLHSAWRAGE
                     EVFAEAALPEGTDAGSFLLHPALLDASLHAIGAGAADGSPGADADAGSGGPLLPFAWSG
                     VSVHATGASTVRVRLAPAGTDAVSLTVADGTGAPVASVESLTLRPVSAGQLRKNSGDAL
                     FTVETVPLALPSDGAEGTTVLWALDTAVPAPTDGPAQPDVVVVPLPDGPEGATGAERVR
                     AVTSATLRLVQHWTAEERTPHLVLVARCDDLAHAAAGALVRSAQAENPGRLTLLETDRP
                     DEAAAQASGVVLSGEPHVIVRGGEAGVPRLVRAVPRTPETATGPTGEAAPAPVGGASGG
                     LGTVLLTGASGALGETLARHLVTAHGVRRLLLVSRRGADAPGAVDLRAELAALGAEAEW
                     AACDVADRDALARLLAAAPVDSVVHTAGVLDDGVIAALTPERLDAVLAPKADAVLNLDE
                     LTGERTTFVLFSSAAGVFGNSGQGNYAAANAFLDAFARHRRAQGRPTVSLAWGLWEQKG
                     AMADALDEAGRTRMARSGVLPLSTEEGLRLFDAALASDEPVFVPVRLDTAALRNRTAES
                     VPALLRGLVRVPARGTAQRAVTGSLADRLAGLAADERDEALLELVRSEAAAVLGHTSAR
                     AVQPAHAFQDLGFDSLTAVELRNRLSTATGLRLSATLVFDHPTPAALARHIGIELLGEA
                     PAPVPGAAAGARTAAGTDEPIAIVGMSCRLPGGVRSPEDLWTLVASGRDGISRFPENRG
                     WDIEGLYDPDPERLGRTYARDGGFLHEAAEFDAGFFGISPREALAMDPQQRLLLEASWE
                     AFERAGIDPETIRGSRTGVFTGLMYHDYGQGPRELPEGVEGLLTTGGSGSVASGRVSYT
                     FGLEGPAVTIDTACSSSLVALHLAVQALRNGECTMALAGGVTVMATPTVFVEFSRQRGL
                     SPDGRCKAFAAGADGTGWGEGVGMLLVERLSDAERNGHQVLAVVRGSAVNQDGASNGLT
                     APNGPAQQRVIRQALASAGLTPGDVDAVEAHGTGTRLGDPIEAQALLATYGQERADGQP
                     LWLGSLKSNIGHTQAAAGVAGVIKMVMALRHGVLPKTLHVDEPTPHVDWSAGDVRLLTE
                     AVDWPETDRPRRAAVSSFGVSGTNAHTIIEQAPAAAATGGTPAPGSGTAVPWVLSGRTE
                     EALRAQAARLASFVDDHDAAAGDGEAALVADVAYSLATTRAAFEHRAAVVGHTLQEMRQ
                     GLAAAASGDTPPGVVTGAARTRGRTVFVLPGQGSQWMGMAAELLETSPVFRERIEACER
                     AFAPHVDWSLTEVLHGTAEAEQDRVDVLQPVLWAMTVALAEVWRSYGVIPDAVVGHSQG
                     EVSAAVIAGALSLEDGARVVARRSLAVRELQGRGAMASVTLPDEEARELVGRWDGRLGI
                     AAVNGPATVVVSGETGAMEELLAHCAAENVQARKVAVDYAAHSPQIELVEEQAREGFVG
                     ISPLPATVPFYSTVTGGKLDPAELGSGYWYRNMRQTVRFHDAIRAALADGHDVFIEVSP
                     HPVQLTGVQDAIEAADAVAAVVPTLRRRDGGIHRLMLSLAEAHGHGVAVDWDAVLPGAR
                     RVDLPTYAFRHERYWLEAGAPAGDVRTAGLDAADHPFLGAAVELPDAGGHLLTGMLSLQ
                     AHPWLADHAVLGTVLLPGTAFVELAAHAAAETGCDLVEELTLQAPLVLPEHGGVALQVL
                     VGAQDDSGRRPLSVHSRAGDGPWLRNATGVLATGATPAETDLGIWPPADAQPVDLDDFY
                     GRLADLGLSYGPAFQGLRAAWRGNDAVYAELAVADGTDTDAFGLHPALLDSALHALGAG
                     GLVPAADGPLLPFAWSRVTLRGTGAAALRVRLAPAGGDTVRLEAADDTGRSVVSVESLT
                     LRPVSVEHLRTNSRDALFTEEWAPLAAPSDAPTPTLRFYDDTAALLAAPETETGAEAAT
                     DAVVVPCPAGQGADAERLRDVLAEVLRLVQWWLSEDRAPRLVLLSRGAVAAGDGPAQDD
                     PVHAAVWGLIRSAQSENPDRVVLLDLDPGLGIDAGAEAERTAATAVRRLVASEEPQAAL
                     RGDVLLLPRLARAATDAPRTGPGFGTGTVLVTGASGALGSLVARHLVTEHGVRSLLLLS
                     RRGATADGAAELQAELTAAGAEVRWAACDAADRDALAEALSGTEVTAVVHTAGVLDDGV
                     IASLTPERLETVLRPKADAVLNLHELAGDVSAFVLFSSLAGTLGTPGQANYAAANAYLD
                     SFARFRRAQGLPAVSLPWGLWQRTGAMTEDLGGTDRNRLSRGGVLPLSDEDGLELLDAA
                     LTLEEPLVVAARLDLAALRNAATPVPPLLRALVGGRPRRTDRAASVPLAQRIAGLPESE
                     RAEAVLDLVRSEAAAVLGHSSAKAVQPDHAFGELGFDSLTAVELRNRMNRATGLRLPAT
                     LIFDHPTPAALAQHILKDLPGGAAGTAPVFDELDRLAAALDGAGAGDVDNVTRTRINMR
                     LQALLARWNGDGPADAGDDGTTGTGHDLSSASDEELYDLLDDELGIS"
     aSDomain        3444..3527
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37160_PKS_Docking_Nterm.
                     1"
                     /evalue="7.40E-13"
                     /label="IE242_RS37160_PKS_Docking_Nterm.1"
                     /locus_tag="IE242_RS37160"
                     /protein_end="31"
                     /protein_start="3"
                     /score="39.8"
                     /tool="antismash"
                     /translation="EDKLRYFLKRVTADLQETRRRLRDHEDA"
     aSDomain        3540..4817
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37160_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="1.80E-186"
                     /label="IE242_RS37160_PKS_KS.1"
                     /locus_tag="IE242_RS37160"
                     /protein_end="461"
                     /protein_start="35"
                     /score="612.1"
                     /tool="antismash"
                     /translation="VAIIGMSCRYPGGVDSPEDLWRLVAGGRDAVSEFPTDRGWDLDAL
                     YDPDPESRGTSYAREGAFLQDPARFDASLFGISPREALAMDPQQRLLLETSWELFERAG
                     IDAASLAGSRTGVFTGVMNHEFLATLQNAPEDLEGYLGTGTSGSVASGRVAYTFGLEGP
                     AVTVDTACSSSLVALHLAVQSLRSGECSLAVAGGVTAMVGPATFVGFSRQRGLAPDGRC
                     KAFAAGADGTGWGEGAGLLLVERLSDARRNGHDILAVVRGSAVNQDGASNGLTAPNGPS
                     QQRVIRQALSAARLTAAQVDVVEAHGTGTRLGDPIEAQALLATYGQARTEDKPLLLGSI
                     KSNIGHTQAAAGVAGVIKMVMAMRNGELPRTLHVDAPSPHVDWSAGAVRLLTEHTPWPA
                     SDEPRRAGISSFGISGTNAHTIIEEAP"
     aSModule        3540..8681
                     /complete
                     /domains="nrpspksdomains_IE242_RS37160_PKS_KS.1"
                     /domains="nrpspksdomains_IE242_RS37160_PKS_AT.1"
                     /domains="nrpspksdomains_IE242_RS37160_PKS_DH.1"
                     /domains="nrpspksdomains_IE242_RS37160_PKS_KR.1"
                     /domains="nrpspksdomains_IE242_RS37160_ACP.1"
                     /locus_tags="IE242_RS37160"
                     /monomer_pairings="mal -> ccmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       3795..3821
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0001"
                     /evalue="6.70E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="IE242_RS37160"
                     /protein_end="129"
                     /protein_start="120"
                     /score="6.6"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     CDS_motif       4023..4070
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0002"
                     /evalue="2.00E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE242_RS37160"
                     /protein_end="212"
                     /protein_start="196"
                     /score="19.7"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     CDS_motif       4446..4490
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0003"
                     /evalue="7.80E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE242_RS37160"
                     /protein_end="352"
                     /protein_start="337"
                     /score="11.8"
                     /tool="antismash"
                     /translation="VEAHGTGTRLGDPIE"
     CDS_motif       4551..4595
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0004"
                     /evalue="2.50E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE242_RS37160"
                     /protein_end="387"
                     /protein_start="372"
                     /score="10.5"
                     /tool="antismash"
                     /translation="GSIKSNIGHTQAAAG"
     CDS_motif       4926..4952
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0005"
                     /evalue="5.00E+01"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE242_RS37160"
                     /protein_end="506"
                     /protein_start="497"
                     /score="-1.9"
                     /tool="antismash"
                     /translation="GPVPWVVSG"
     aSDomain        5193..6023
                     /ASF="Malonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37160_PKS_AT.1"
                     /evalue="3.70E-103"
                     /label="IE242_RS37160_PKS_AT.1"
                     /locus_tag="IE242_RS37160"
                     /protein_end="863"
                     /protein_start="586"
                     /score="336.9"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFSGQGSQRPGMGRELYAAHPAFAAAYDEVCSHLGAVVDVDSEEL
                     HRTGAAQPALFAVEVALFRLLESWGVRPDYVAGHSVGEIAAAHAAGVLSLEDAAKLVSA
                     RAALMQALPEGGAMVAVQATEDEVLPHLSDGVGVAAVNGPRSVVLSGAEAPVLEIAEIF
                     GRQGRKTSRLKVSHAFHSPLMEPMLAEFGEVVAGLAHEQPRIPVVSTLTGRPAEPYTPE
                     YWVRHVRETVRFADGARTLHELGVTTFVEIGPGGVLSGLTQGCLDEDVVTVPALR"
     CDS_motif       5196..5243
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0006"
                     /evalue="9.50E-06"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="IE242_RS37160"
                     /protein_end="603"
                     /protein_start="587"
                     /score="18.1"
                     /tool="antismash"
                     /translation="FSGQGSQRPGMGRELY"
     CDS_motif       5337..5390
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0007"
                     /evalue="1.90E-03"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="IE242_RS37160"
                     /protein_end="652"
                     /protein_start="634"
                     /score="11.6"
                     /tool="antismash"
                     /translation="GAAQPALFAVEVALFRLL"
     CDS_motif       5400..5522
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0008"
                     /evalue="2.20E-22"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="IE242_RS37160"
                     /protein_end="696"
                     /protein_start="655"
                     /score="71.3"
                     /tool="antismash"
                     /translation="GVRPDYVAGHSVGEIAAAHAAGVLSLEDAAKLVSARAALMQ"
     CDS_motif       5607..5645
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0009"
                     /evalue="7.60E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE242_RS37160"
                     /protein_end="737"
                     /protein_start="724"
                     /score="12.8"
                     /tool="antismash"
                     /translation="AAVNGPRSVVLSG"
     CDS_motif       5859..5894
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0010"
                     /evalue="1.10E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="IE242_RS37160"
                     /protein_end="820"
                     /protein_start="808"
                     /score="15.5"
                     /tool="antismash"
                     /translation="YWVRHVRETVRF"
     aSDomain        6228..6731
                     /ASF="catalytic triad H,G,P found: False"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37160_PKS_DH.1"
                     /evalue="4.50E-65"
                     /label="IE242_RS37160_PKS_DH.1"
                     /locus_tag="IE242_RS37160"
                     /protein_end="1099"
                     /protein_start="931"
                     /score="211.0"
                     /tool="antismash"
                     /translation="HPLLGAAVSLAGGDERLLTGRLSLRTHPWLSDHAVLGTVLLPGTA
                     FVELAVRAADEAGCDLLEDLTLEAPLVIPEQGGVAVQVWVGAADDSGRRPLTVHSRPEE
                     DAHLPWVRHATGSVAEATAETGAGAAGSTLATWPPAGAEPIALDGFHDRLAALGLSYGP
                     TFRGL"
     CDS_motif       6312..6389
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0011"
                     /evalue="2.00E-09"
                     /label="PKSI-DH_m2"
                     /locus_tag="IE242_RS37160"
                     /protein_end="985"
                     /protein_start="959"
                     /score="29.9"
                     /tool="antismash"
                     /translation="WLSDHAVLGTVLLPGTAFVELAVRAA"
     CDS_motif       6699..6731
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0012"
                     /evalue="8.20E-02"
                     /label="PKSI-DH_m3"
                     /locus_tag="IE242_RS37160"
                     /protein_end="1099"
                     /protein_start="1088"
                     /score="6.4"
                     /tool="antismash"
                     /translation="GLSYGPTFRGL"
     aSDomain        7644..8162
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37160_PKS_KR.1"
                     /evalue="6.10E-54"
                     /label="IE242_RS37160_PKS_KR.1"
                     /locus_tag="IE242_RS37160"
                     /protein_end="1576"
                     /protein_start="1403"
                     /score="174.7"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GTVLLTGASGALGETLARHLVTAHGVRRLLLVSRRGADAPGAVDL
                     RAELAALGAEAEWAACDVADRDALARLLAAAPVDSVVHTAGVLDDGVIAALTPERLDAV
                     LAPKADAVLNLDELTGERTTFVLFSSAAGVFGNSGQGNYAAANAFLDAFARHRRAQGRP
                     TVSLAWGLWE"
     CDS_motif       7647..7748
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0013"
                     /evalue="8.80E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE242_RS37160"
                     /protein_end="1438"
                     /protein_start="1404"
                     /score="21.6"
                     /tool="antismash"
                     /translation="TVLLTGASGALGETLARHLVTAHGVRRLLLVSRR"
     CDS_motif       8016..8117
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0014"
                     /evalue="7.20E-21"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE242_RS37160"
                     /protein_end="1561"
                     /protein_start="1527"
                     /score="66.8"
                     /tool="antismash"
                     /translation="FVLFSSAAGVFGNSGQGNYAAANAFLDAFARHRR"
     aSDomain        8472..8681
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37160_ACP.1"
                     /evalue="2.10E-32"
                     /label="IE242_RS37160_ACP.1"
                     /locus_tag="IE242_RS37160"
                     /protein_end="1749"
                     /protein_start="1679"
                     /score="103.2"
                     /tool="antismash"
                     /translation="LELVRSEAAAVLGHTSARAVQPAHAFQDLGFDSLTAVELRNRLST
                     ATGLRLSATLVFDHPTPAALARHIG"
     aSDomain        8763..10040
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37160_PKS_KS.2"
                     /domain_subtypes="Modular-KS"
                     /evalue="7.80E-190"
                     /label="IE242_RS37160_PKS_KS.2"
                     /locus_tag="IE242_RS37160"
                     /protein_end="2202"
                     /protein_start="1776"
                     /score="623.2"
                     /tool="antismash"
                     /translation="IAIVGMSCRLPGGVRSPEDLWTLVASGRDGISRFPENRGWDIEGL
                     YDPDPERLGRTYARDGGFLHEAAEFDAGFFGISPREALAMDPQQRLLLEASWEAFERAG
                     IDPETIRGSRTGVFTGLMYHDYGQGPRELPEGVEGLLTTGGSGSVASGRVSYTFGLEGP
                     AVTIDTACSSSLVALHLAVQALRNGECTMALAGGVTVMATPTVFVEFSRQRGLSPDGRC
                     KAFAAGADGTGWGEGVGMLLVERLSDAERNGHQVLAVVRGSAVNQDGASNGLTAPNGPA
                     QQRVIRQALASAGLTPGDVDAVEAHGTGTRLGDPIEAQALLATYGQERADGQPLWLGSL
                     KSNIGHTQAAAGVAGVIKMVMALRHGVLPKTLHVDEPTPHVDWSAGDVRLLTEAVDWPE
                     TDRPRRAAVSSFGVSGTNAHTIIEQAP"
     aSModule        8763..13886
                     /complete
                     /domains="nrpspksdomains_IE242_RS37160_PKS_KS.2"
                     /domains="nrpspksdomains_IE242_RS37160_PKS_AT.2"
                     /domains="nrpspksdomains_IE242_RS37160_PKS_DH.2"
                     /domains="nrpspksdomains_IE242_RS37160_PKS_KR.2"
                     /domains="nrpspksdomains_IE242_RS37160_PKS_PP.1"
                     /locus_tags="IE242_RS37160"
                     /monomer_pairings="pk -> pk"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       9018..9044
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0015"
                     /evalue="6.70E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="IE242_RS37160"
                     /protein_end="1870"
                     /protein_start="1861"
                     /score="6.6"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     CDS_motif       9246..9293
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0016"
                     /evalue="2.10E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE242_RS37160"
                     /protein_end="1953"
                     /protein_start="1937"
                     /score="19.6"
                     /tool="antismash"
                     /translation="GPAVTIDTACSSSLVA"
     CDS_motif       9669..9713
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0017"
                     /evalue="9.90E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE242_RS37160"
                     /protein_end="2093"
                     /protein_start="2078"
                     /score="11.6"
                     /tool="antismash"
                     /translation="VEAHGTGTRLGDPIE"
     CDS_motif       9774..9818
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0018"
                     /evalue="5.10E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE242_RS37160"
                     /protein_end="2128"
                     /protein_start="2113"
                     /score="9.7"
                     /tool="antismash"
                     /translation="GSLKSNIGHTQAAAG"
     CDS_motif       10371..10427
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0019"
                     /evalue="7.10E-08"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE242_RS37160"
                     /protein_end="2331"
                     /protein_start="2312"
                     /score="24.4"
                     /tool="antismash"
                     /translation="VFVLPGQGSQWMGMAAELL"
     aSDomain        10377..11261
                     /ASF="Neither malonyl-CoA or methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37160_PKS_AT.2"
                     /evalue="3.40E-104"
                     /label="IE242_RS37160_PKS_AT.2"
                     /locus_tag="IE242_RS37160"
                     /protein_end="2609"
                     /protein_start="2314"
                     /score="340.3"
                     /specificity="substrate consensus: pk"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: emal"
                     /tool="antismash"
                     /translation="VLPGQGSQWMGMAAELLETSPVFRERIEACERAFAPHVDWSLTEV
                     LHGTAEAEQDRVDVLQPVLWAMTVALAEVWRSYGVIPDAVVGHSQGEVSAAVIAGALSL
                     EDGARVVARRSLAVRELQGRGAMASVTLPDEEARELVGRWDGRLGIAAVNGPATVVVSG
                     ETGAMEELLAHCAAENVQARKVAVDYAAHSPQIELVEEQAREGFVGISPLPATVPFYST
                     VTGGKLDPAELGSGYWYRNMRQTVRFHDAIRAALADGHDVFIEVSPHPVQLTGVQDAIE
                     AADAVAAVVPTLRR"
     CDS_motif       10539..10607
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0020"
                     /evalue="1.40E-07"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="IE242_RS37160"
                     /protein_end="2391"
                     /protein_start="2368"
                     /score="24.0"
                     /tool="antismash"
                     /translation="DRVDVLQPVLWAMTVALAEVWRS"
     CDS_motif       10611..10721
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0021"
                     /evalue="5.70E-18"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="IE242_RS37160"
                     /protein_end="2429"
                     /protein_start="2392"
                     /score="56.8"
                     /tool="antismash"
                     /translation="GVIPDAVVGHSQGEVSAAVIAGALSLEDGARVVARRS"
     CDS_motif       10827..10865
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0022"
                     /evalue="2.10E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE242_RS37160"
                     /protein_end="2477"
                     /protein_start="2464"
                     /score="11.4"
                     /tool="antismash"
                     /translation="AAVNGPATVVVSG"
     CDS_motif       10935..10967
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0023"
                     /evalue="9.30E-03"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="IE242_RS37160"
                     /protein_end="2511"
                     /protein_start="2500"
                     /score="9.1"
                     /tool="antismash"
                     /translation="VDYAAHSPQIE"
     CDS_motif       11073..11120
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0024"
                     /evalue="7.20E-04"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="IE242_RS37160"
                     /protein_end="2562"
                     /protein_start="2546"
                     /score="12.1"
                     /tool="antismash"
                     /translation="LGSGYWYRNMRQTVRF"
     aSDomain        11460..11939
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37160_PKS_DH.2"
                     /evalue="2.80E-64"
                     /label="IE242_RS37160_PKS_DH.2"
                     /locus_tag="IE242_RS37160"
                     /protein_end="2835"
                     /protein_start="2675"
                     /score="208.4"
                     /tool="antismash"
                     /translation="HPFLGAAVELPDAGGHLLTGMLSLQAHPWLADHAVLGTVLLPGTA
                     FVELAAHAAAETGCDLVEELTLQAPLVLPEHGGVALQVLVGAQDDSGRRPLSVHSRAGD
                     GPWLRNATGVLATGATPAETDLGIWPPADAQPVDLDDFYGRLADLGLSYGPAFQGL"
     CDS_motif       11544..11621
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0025"
                     /evalue="9.60E-09"
                     /label="PKSI-DH_m2"
                     /locus_tag="IE242_RS37160"
                     /protein_end="2729"
                     /protein_start="2703"
                     /score="27.7"
                     /tool="antismash"
                     /translation="WLADHAVLGTVLLPGTAFVELAAHAA"
     CDS_motif       11907..11939
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0026"
                     /evalue="2.60E-02"
                     /label="PKSI-DH_m3"
                     /locus_tag="IE242_RS37160"
                     /protein_end="2835"
                     /protein_start="2824"
                     /score="7.8"
                     /tool="antismash"
                     /translation="GLSYGPAFQGL"
     aSDomain        12852..13370
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37160_PKS_KR.2"
                     /evalue="5.60E-52"
                     /label="IE242_RS37160_PKS_KR.2"
                     /locus_tag="IE242_RS37160"
                     /protein_end="3312"
                     /protein_start="3139"
                     /score="168.3"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GTVLVTGASGALGSLVARHLVTEHGVRSLLLLSRRGATADGAAEL
                     QAELTAAGAEVRWAACDAADRDALAEALSGTEVTAVVHTAGVLDDGVIASLTPERLETV
                     LRPKADAVLNLHELAGDVSAFVLFSSLAGTLGTPGQANYAAANAYLDSFARFRRAQGLP
                     AVSLPWGLWQ"
     CDS_motif       12855..12956
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0027"
                     /evalue="1.10E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE242_RS37160"
                     /protein_end="3174"
                     /protein_start="3140"
                     /score="21.3"
                     /tool="antismash"
                     /translation="TVLVTGASGALGSLVARHLVTEHGVRSLLLLSRR"
     CDS_motif       13224..13325
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37160_0028"
                     /evalue="2.50E-19"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE242_RS37160"
                     /protein_end="3297"
                     /protein_start="3263"
                     /score="61.8"
                     /tool="antismash"
                     /translation="FVLFSSLAGTLGTPGQANYAAANAYLDSFARFRR"
     aSDomain        13638..13886
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37160_PKS_PP.1"
                     /evalue="3.90E-33"
                     /label="IE242_RS37160_PKS_PP.1"
                     /locus_tag="IE242_RS37160"
                     /protein_end="3484"
                     /protein_start="3401"
                     /score="105.6"
                     /tool="antismash"
                     /translation="AGLPESERAEAVLDLVRSEAAAVLGHSSAKAVQPDHAFGELGFDS
                     LTAVELRNRMNRATGLRLPATLIFDHPTPAALAQHILK"
     aSDomain        13917..14150
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37160_PKS_Docking_Cterm.
                     1"
                     /evalue="6.30E-13"
                     /label="IE242_RS37160_PKS_Docking_Cterm.1"
                     /locus_tag="IE242_RS37160"
                     /protein_end="3572"
                     /protein_start="3494"
                     /score="41.4"
                     /tool="antismash"
                     /translation="PVFDELDRLAAALDGAGAGDVDNVTRTRINMRLQALLARWNGDGP
                     ADAGDDGTTGTGHDLSSASDEELYDLLDDELGI"
     gene            14134..19725
                     /locus_tag="IE242_RS37165"
                     /old_locus_tag="GCM10010365_76130"
     CDS             14134..19725
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (22-49). E-value:
                     9.8e-15. Score: 45.8. Matches aSDomain:
                     nrpspksdomains_IE242_RS37165_PKS_Docking_Nterm.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (54-478). E-value:
                     2.8e-184. Score: 604.9. Matches aSDomain:
                     nrpspksdomains_IE242_RS37165_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (603-883). E-value: 1.3e-104.
                     Score: 341.7. Matches aSDomain:
                     nrpspksdomains_IE242_RS37165_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (948-1108). E-value: 2.1e-45.
                     Score: 147.0. Matches aSDomain:
                     nrpspksdomains_IE242_RS37165_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (1417-1597). E-value: 9.9e-60.
                     Score: 193.5. Matches aSDomain:
                     nrpspksdomains_IE242_RS37165_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1689-1774). E-value: 3.6e-31.
                     Score: 99.3. Matches aSDomain:
                     nrpspksdomains_IE242_RS37165_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (1784-1862). E-value:
                     1.9e-20. Score: 65.5. Matches aSDomain:
                     nrpspksdomains_IE242_RS37165_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981854.1"
                     /locus_tag="IE242_RS37165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_76130"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_373299690.1"
                     /sec_met_domain="mod_KS (E-value: 7.2e-233, bitscore:
                     761.0, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 7.8e-99, bitscore:
                     318.4, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 8.8e-106, bitscore:
                     341.7, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 3.5e-63, bitscore:
                     200.8, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.5e-15, bitscore:
                     44.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNSASPELGKATKGRATSMMNEDKLRDYLKRATTDLRQARRRVR
                     ELEALGQEPIAIVGMGCRFPGGVGSPEELWRLLAEGTDAVSDFPDDRGWDLDALYDPDP
                     DRPGTVYTRQGGFLRDAADFDADFFGISPREALAMDPQQRLLLETSWEAFEHAGIDPAD
                     LRGSRTGVFAGLMYHDYGFTPGVLPEGVEGLMSTGNSGSVASGRIAYTFGFEGPAVTVD
                     TACSSSLVALHLAVQALRAGECSMALAGGVTVMAGPSAFVEFSRQRGLAPDGRCKSFAA
                     AADGASWSEGAGLLLVERLRDARRLGHQVLAVVRSSAVNQDGASNGLTAPNGPSQQRVI
                     LEALAGARLSAEEVDAVEAHGTGTPLGDPIEAQALLATYGQERDRPLLVGSLKSNIGHT
                     QAAAGVAGVIKMVLAMRHGVLPKTLHVDEPTPRVDWSAGSVGLLTEATAWPATNRPRRA
                     GVSSFGISGTNAHVILEEAPVEAPEEAPQEQAPDPEPAAGEAAVPAGERTRTKAAVVPW
                     VLSAKTGQALRAQARRLLSSVDLATAAPADVAFSLAANRSALEHRAAVVGADEEELLAG
                     LAALAAGEPAAQVVTGRAASDQGKVGFLFSGQGSQRVGMGRELYAAFPVFAAAYDEVCA
                     HLDVVLDVDEEELNRTGAAQPALFAVEVALFRLLESWGVRPDYVAGHSVGEVAAAHVAG
                     VLSLEDAAALVSARARLMQALPEGGAMVAVQASEEEVLPHLAEGVGVAAINGPRSVVVS
                     GAEAVVLAIGEVFREQGRKTSRLKVSHAFHSPLMEPMLAEFGEVVAGLSFEQPRIPVVS
                     NLTGRLVESYTPEYWVEHVREAVRFADGIATLHELGVGTFVEIGPGGVLSALAQGCFDG
                     DADVVTVPVLRADRPEEQAVVTALADLHVHGHEVDWRAFFPGARRVDLPTYAFQRERYW
                     LEGLAVTDVSSAGLDSAGHALLGAVVETAGTQEVLFTGRLSPAELPWIAEHTVSGVPVL
                     PVAAFVELALSAGRRTGFPYLTRLDVDAPLVLAEHGAVRIQVRIGVADDPGRRSVRVFS
                     RSAAAGTGEAWVCHTTGELTRDAPAPELDLTAWPPAGAEAVDVAGRPGLRAAWRAGDEL
                     YAEAELPATERNRADRYTLHPVLLDAALGLMAPDRAADPGVFLLPHAWSGMSVHTPGPG
                     AVRIRVRPTGDGTVALELSGADGSPVASATSVRTRTMTAQQVLASRVAHQDWMFEIDWV
                     EHTAAPATAPASGAGWAVLGDEGSHADIGALREAVDGGAAVPAHVLLPCAPSDGDAAAA
                     TRGTLAEVLSAVQDWVADERFSDARLVVMTCGGAGPDGPAVDPAHVAVSGLVKAAQAEH
                     PDRLLLVDTDDSDDSSSYDGTDPDSAGGLDPALAAALAALDEPQAAVRDGKLLVPRLAR
                     ISPPAEPAGPAWDPEGTVLLTGATGGLGLSLARHLVVERGARRLLLASRRGPAAEGVAE
                     LVTELSGLGAHVDVAACDIADRQALAELLASVPAEHPLVAVVHAAAALDDGVVTALTPE
                     RLDIVLRPKVDGALHLHELTKDLDLSAFVLFSSLAGVLGSAGAASYAAANAFLDGLARR
                     RRAAGLPGTSLAWGLWTDNGGMGDRITDADRDRMGRSGVVPFTPAEGLALFDAALTVDR
                     PVLVPVRLDVPQLRAMARAGMLPAVFRGLAGDTGSPADAAEGTGATPLAARLAGMPEAD
                     QEKALLELVRHQAAAALGHVDASRVEPTTAFRDIGFDSLTAVELRNRLKAATGLRLKPT
                     LVFDHPNPVAIARLLHKDLLLDSAAEAPPVLAELDRLEEQLAALAPQDALRDKVTARLK
                     ALLWKWTDTRHDAAADDAGPGTGSELDRLDAATDDEMFDLIDQELGSL"
     aSDomain        14200..14280
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37165_PKS_Docking_Nterm.
                     1"
                     /evalue="9.80E-15"
                     /label="IE242_RS37165_PKS_Docking_Nterm.1"
                     /locus_tag="IE242_RS37165"
                     /protein_end="49"
                     /protein_start="22"
                     /score="45.8"
                     /tool="antismash"
                     /translation="EDKLRDYLKRATTDLRQARRRVRELEA"
     aSDomain        14296..15567
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37165_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="2.80E-184"
                     /label="IE242_RS37165_PKS_KS.1"
                     /locus_tag="IE242_RS37165"
                     /protein_end="478"
                     /protein_start="54"
                     /score="604.9"
                     /tool="antismash"
                     /translation="IAIVGMGCRFPGGVGSPEELWRLLAEGTDAVSDFPDDRGWDLDAL
                     YDPDPDRPGTVYTRQGGFLRDAADFDADFFGISPREALAMDPQQRLLLETSWEAFEHAG
                     IDPADLRGSRTGVFAGLMYHDYGFTPGVLPEGVEGLMSTGNSGSVASGRIAYTFGFEGP
                     AVTVDTACSSSLVALHLAVQALRAGECSMALAGGVTVMAGPSAFVEFSRQRGLAPDGRC
                     KSFAAAADGASWSEGAGLLLVERLRDARRLGHQVLAVVRSSAVNQDGASNGLTAPNGPS
                     QQRVILEALAGARLSAEEVDAVEAHGTGTPLGDPIEAQALLATYGQERDRPLLVGSLKS
                     NIGHTQAAAGVAGVIKMVLAMRHGVLPKTLHVDEPTPRVDWSAGSVGLLTEATAWPATN
                     RPRRAGVSSFGISGTNAHVILEEAP"
     aSModule        14296..19455
                     /complete
                     /domains="nrpspksdomains_IE242_RS37165_PKS_KS.1"
                     /domains="nrpspksdomains_IE242_RS37165_PKS_AT.1"
                     /domains="nrpspksdomains_IE242_RS37165_PKS_DH.1"
                     /domains="nrpspksdomains_IE242_RS37165_PKS_KR.1"
                     /domains="nrpspksdomains_IE242_RS37165_PKS_PP.1"
                     /locus_tags="IE242_RS37165"
                     /monomer_pairings="mal -> ccmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       14551..14577
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37165_0001"
                     /evalue="3.00E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="IE242_RS37165"
                     /protein_end="148"
                     /protein_start="139"
                     /score="7.5"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     CDS_motif       14779..14826
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37165_0002"
                     /evalue="9.30E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE242_RS37165"
                     /protein_end="231"
                     /protein_start="215"
                     /score="20.7"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     CDS_motif       15139..15159
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37165_0003"
                     /evalue="4.90E+01"
                     /label="PKSI-KS_m2"
                     /locus_tag="IE242_RS37165"
                     /protein_end="342"
                     /protein_start="335"
                     /score="-1.3"
                     /tool="antismash"
                     /translation="QQRVILE"
     CDS_motif       15202..15246
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37165_0004"
                     /evalue="5.40E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE242_RS37165"
                     /protein_end="371"
                     /protein_start="356"
                     /score="12.3"
                     /tool="antismash"
                     /translation="VEAHGTGTPLGDPIE"
     CDS_motif       15301..15345
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37165_0005"
                     /evalue="2.30E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE242_RS37165"
                     /protein_end="404"
                     /protein_start="389"
                     /score="10.7"
                     /tool="antismash"
                     /translation="GSLKSNIGHTQAAAG"
     aSDomain        15943..16782
                     /ASF="Malonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37165_PKS_AT.1"
                     /evalue="1.30E-104"
                     /label="IE242_RS37165_PKS_AT.1"
                     /locus_tag="IE242_RS37165"
                     /protein_end="883"
                     /protein_start="603"
                     /score="341.7"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFSGQGSQRVGMGRELYAAFPVFAAAYDEVCAHLDVVLDVDEEEL
                     NRTGAAQPALFAVEVALFRLLESWGVRPDYVAGHSVGEVAAAHVAGVLSLEDAAALVSA
                     RARLMQALPEGGAMVAVQASEEEVLPHLAEGVGVAAINGPRSVVVSGAEAVVLAIGEVF
                     REQGRKTSRLKVSHAFHSPLMEPMLAEFGEVVAGLSFEQPRIPVVSNLTGRLVESYTPE
                     YWVEHVREAVRFADGIATLHELGVGTFVEIGPGGVLSALAQGCFDGDADVVTVPVLRA"
     CDS_motif       15946..15993
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37165_0006"
                     /evalue="6.00E-06"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="IE242_RS37165"
                     /protein_end="620"
                     /protein_start="604"
                     /score="18.7"
                     /tool="antismash"
                     /translation="FSGQGSQRVGMGRELY"
     CDS_motif       16084..16140
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37165_0007"
                     /evalue="7.90E-04"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="IE242_RS37165"
                     /protein_end="669"
                     /protein_start="650"
                     /score="12.7"
                     /tool="antismash"
                     /translation="TGAAQPALFAVEVALFRLL"
     CDS_motif       16150..16272
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37165_0008"
                     /evalue="4.60E-23"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="IE242_RS37165"
                     /protein_end="713"
                     /protein_start="672"
                     /score="73.5"
                     /tool="antismash"
                     /translation="GVRPDYVAGHSVGEVAAAHVAGVLSLEDAAALVSARARLMQ"
     CDS_motif       16357..16395
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37165_0009"
                     /evalue="1.20E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE242_RS37165"
                     /protein_end="754"
                     /protein_start="741"
                     /score="15.2"
                     /tool="antismash"
                     /translation="AAINGPRSVVVSG"
     CDS_motif       16609..16644
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37165_0010"
                     /evalue="1.30E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="IE242_RS37165"
                     /protein_end="837"
                     /protein_start="825"
                     /score="15.3"
                     /tool="antismash"
                     /translation="YWVEHVREAVRF"
     aSDomain        16978..17457
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37165_PKS_DH.1"
                     /evalue="2.10E-45"
                     /label="IE242_RS37165_PKS_DH.1"
                     /locus_tag="IE242_RS37165"
                     /protein_end="1108"
                     /protein_start="948"
                     /score="147.0"
                     /tool="antismash"
                     /translation="HALLGAVVETAGTQEVLFTGRLSPAELPWIAEHTVSGVPVLPVAA
                     FVELALSAGRRTGFPYLTRLDVDAPLVLAEHGAVRIQVRIGVADDPGRRSVRVFSRSAA
                     AGTGEAWVCHTTGELTRDAPAPELDLTAWPPAGAEAVDVAGRPGLRAAWRAGDELY"
     CDS_motif       17062..17139
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37165_0011"
                     /evalue="2.00E-08"
                     /label="PKSI-DH_m2"
                     /locus_tag="IE242_RS37165"
                     /protein_end="1002"
                     /protein_start="976"
                     /score="26.7"
                     /tool="antismash"
                     /translation="WIAEHTVSGVPVLPVAAFVELALSAG"
     aSDomain        18385..18924
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37165_PKS_KR.1"
                     /evalue="9.90E-60"
                     /label="IE242_RS37165_PKS_KR.1"
                     /locus_tag="IE242_RS37165"
                     /protein_end="1597"
                     /protein_start="1417"
                     /score="193.5"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GTVLLTGATGGLGLSLARHLVVERGARRLLLASRRGPAAEGVAEL
                     VTELSGLGAHVDVAACDIADRQALAELLASVPAEHPLVAVVHAAAALDDGVVTALTPER
                     LDIVLRPKVDGALHLHELTKDLDLSAFVLFSSLAGVLGSAGAASYAAANAFLDGLARRR
                     RAAGLPGTSLAWGLWTD"
     CDS_motif       18388..18489
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37165_0012"
                     /evalue="9.60E-11"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE242_RS37165"
                     /protein_end="1452"
                     /protein_start="1418"
                     /score="34.3"
                     /tool="antismash"
                     /translation="TVLLTGATGGLGLSLARHLVVERGARRLLLASRR"
     CDS_motif       18772..18876
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37165_0013"
                     /evalue="1.60E-16"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE242_RS37165"
                     /protein_end="1581"
                     /protein_start="1546"
                     /score="52.8"
                     /tool="antismash"
                     /translation="AFVLFSSLAGVLGSAGAASYAAANAFLDGLARRRR"
     aSDomain        19201..19455
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37165_PKS_PP.1"
                     /evalue="3.60E-31"
                     /label="IE242_RS37165_PKS_PP.1"
                     /locus_tag="IE242_RS37165"
                     /protein_end="1774"
                     /protein_start="1689"
                     /score="99.3"
                     /tool="antismash"
                     /translation="LAGMPEADQEKALLELVRHQAAAALGHVDASRVEPTTAFRDIGFD
                     SLTAVELRNRLKAATGLRLKPTLVFDHPNPVAIARLLHKD"
     aSDomain        19486..19719
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37165_PKS_Docking_Cterm.
                     1"
                     /evalue="1.90E-20"
                     /label="IE242_RS37165_PKS_Docking_Cterm.1"
                     /locus_tag="IE242_RS37165"
                     /protein_end="1862"
                     /protein_start="1784"
                     /score="65.5"
                     /tool="antismash"
                     /translation="PVLAELDRLEEQLAALAPQDALRDKVTARLKALLWKWTDTRHDAA
                     ADDAGPGTGSELDRLDAATDDEMFDLIDQELGS"
     gene            19760..>21517
                     /locus_tag="IE242_RS37170"
     CDS             19760..>21517
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (3-31). E-value:
                     4.7e-15. Score: 46.8. Matches aSDomain:
                     nrpspksdomains_IE242_RS37170_PKS_Docking_Nterm.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (35-460). E-value:
                     1e-183. Score: 603.0. Matches aSDomain:
                     nrpspksdomains_IE242_RS37170_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049322.1"
                     /locus_tag="IE242_RS37170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I polyketide synthase"
                     /protein_id="WP_189867492.1"
                     /sec_met_domain="mod_KS (E-value: 3.4e-229, bitscore:
                     748.9, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 3.7e-97, bitscore:
                     312.9, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNDDKLRDYLKRVMVDLRQTRRQLGELEAKDTEPIAIVGMACRY
                     PGGVGSPEDLWQLVASGGDGVSGFPTDRGWDLDAIHDPEPGKTGRTYVREGGFLHDAGE
                     FDPAFFGISPREALVMDPQQRLLLQTSWEAFERAGIDPVTARGSRTGVFVGTNGQDHAY
                     LQRPDADIEAHLVTANTAAVVSGRISYALGLEGPAVTVDTACSSSLVALHLAAQALRRG
                     ECSLALAGGVTVMATPNTFIAFSAQRGLSPDGRCRAFSSTADGTGMSEGVGVLLLERLS
                     DARRLGHDVLAVIRGSAVNQDGASNGLTAPNGPSQERVIRQALENARLTASQVDAVEAH
                     GTATTLGDPIEAEALLATYGQEREDDRPLWLGSVKSNFGHTQAASGVAGVIKMVMAIRN
                     GVLPQTLHVEEPTDQVDWSSGGVRLLTEAVQWPESGHPRRAAVSSFGVSGTNAHTIIEQ
                     APASEEEPAAEPAGAPVAGALPWVLSARSEAALRAQAQRLLSFLEDDRGGSGRSPADIG
                     FSLATTRTAWDRRAAVVGESPEALTEAVRALASGTPSAAVVRNAARLGGKVGFLFSGQG
                     SQRVGMGREL"
     aSDomain        19769..19852
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37170_PKS_Docking_Nterm.
                     1"
                     /evalue="4.70E-15"
                     /label="IE242_RS37170_PKS_Docking_Nterm.1"
                     /locus_tag="IE242_RS37170"
                     /protein_end="31"
                     /protein_start="3"
                     /score="46.8"
                     /tool="antismash"
                     /translation="DDKLRDYLKRVMVDLRQTRRQLGELEAK"
     aSDomain        19865..21139
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS37170_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="1.00E-183"
                     /label="IE242_RS37170_PKS_KS.1"
                     /locus_tag="IE242_RS37170"
                     /protein_end="460"
                     /protein_start="35"
                     /score="603.0"
                     /tool="antismash"
                     /translation="IAIVGMACRYPGGVGSPEDLWQLVASGGDGVSGFPTDRGWDLDAI
                     HDPEPGKTGRTYVREGGFLHDAGEFDPAFFGISPREALVMDPQQRLLLQTSWEAFERAG
                     IDPVTARGSRTGVFVGTNGQDHAYLQRPDADIEAHLVTANTAAVVSGRISYALGLEGPA
                     VTVDTACSSSLVALHLAAQALRRGECSLALAGGVTVMATPNTFIAFSAQRGLSPDGRCR
                     AFSSTADGTGMSEGVGVLLLERLSDARRLGHDVLAVIRGSAVNQDGASNGLTAPNGPSQ
                     ERVIRQALENARLTASQVDAVEAHGTATTLGDPIEAEALLATYGQEREDDRPLWLGSVK
                     SNFGHTQAASGVAGVIKMVMAIRNGVLPQTLHVEEPTDQVDWSSGGVRLLTEAVQWPES
                     GHPRRAAVSSFGVSGTNAHTIIEQAP"
     CDS_motif       20120..20146
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37170_0001"
                     /evalue="1.90E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="IE242_RS37170"
                     /protein_end="129"
                     /protein_start="120"
                     /score="8.1"
                     /tool="antismash"
                     /translation="DPQQRLLLQ"
     CDS_motif       20345..20392
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37170_0002"
                     /evalue="2.40E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE242_RS37170"
                     /protein_end="211"
                     /protein_start="195"
                     /score="22.5"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     CDS_motif       20768..20812
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37170_0003"
                     /evalue="6.70E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE242_RS37170"
                     /protein_end="351"
                     /protein_start="336"
                     /score="12.0"
                     /tool="antismash"
                     /translation="VEAHGTATTLGDPIE"
     CDS_motif       20873..20917
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37170_0004"
                     /evalue="6.80E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE242_RS37170"
                     /protein_end="386"
                     /protein_start="371"
                     /score="12.1"
                     /tool="antismash"
                     /translation="GSVKSNFGHTQAASG"
     CDS_motif       21467..>21517
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS37170_0005"
                     /evalue="7.80E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE242_RS37170"
                     /protein_end="586"
                     /protein_start="569"
                     /score="18.3"
                     /tool="antismash"
                     /translation="FLFSGQGSQRVGMGREL"
ORIGIN
        1 tccgaggagg aggtgctgcc gcacctggcc gagggtgtgg gtgtcgcggc catcaacggg
       61 ccgcgctcgg tggtggtctc gggtgccgag gcggcggtcc tcgccatcgg tgaggtgttc
      121 cgggagcagg gccgcaagac ctcccggctg aaggtgagtc atgcgttcca ctcgccgctg
      181 atggagccga tgctggcgga gttcggtgag gtggtcgccg gtctgtcgtt cgagcagccg
      241 cggattccgg tggtgtccaa cctcaccggg cggctggtgg aggcgtacac gccggagtac
      301 tgggtggagc atgtgcgcga ggcggtgcgg ttcgccgacg gcatcgcgac gctgcatgag
      361 ctgggtgtgg gcacgttcgt ggagatcggg ccggggggtg tcctgagcgc cctcgcccag
      421 ggctgcttcg acggcgacgc ggacgtcgtc accgtgcccg tcctgcgggc cgaccgcccc
      481 gaggagcagg ccgtcgtcac cgccctcgcc gacctgcacg tccacggtgt ctccccggac
      541 tggcaggtgc tcttccccgg cgcccgccgc gtcgacctgc cgacctacgc cttccagcgc
      601 gagcgctact ggctcgacgc gcccgaggag ttcaccggcg gtgccgccgc caccggactc
      661 ggactgagcg cggcggaaca cccgctggcc ggtgcggcgg tcgcgctgcc cggcgccggc
      721 ggattcctgg tcaccgggcg gctctcgctc aggacacacc cctggctcgc cgaccacacg
      781 gtcatgggca acgtgctgct gccgggcacc gcgctcgtgg agctggcggt gcgagcggcc
      841 gacgaggccg ggtgcgcgca ggtcgaggac ctgacgctgg aagcgccgct gatcgtcccg
      901 gaccgcgggg gtgtggccgt acaggtatgg gtcgggccgg aggaagagcc cggccggcgc
      961 gcgctgagcg tgcactcccg tccagaggac gcaccggacg tcgcaccgtg ggtgcggcac
     1021 gccgtcggct tcctgaccgg cgaactgccc gagccgccgc atggaacgga cctcggggtg
     1081 tggccgccgg cgggtgcgga ggccgtcgat ctggaggggt actacgaggg cctggacgca
     1141 ctcggcctgg gctacggccc ggtcttccgg ggcctgcgat cggtgtggcg cagcggggac
     1201 gacgtcctcg ccgaggtcgt ccttcccgag gacgtggagg cgggagcgtt cgccgtccac
     1261 ccggcgctgc tggacgcggc gctgcacgcg atcggcgcgg gcgggctcgt acccgtcgcg
     1321 gacggtccgc tgctgccctt cgcatggtcg gaggtggggg tgcgggccgc gggtgcgacg
     1381 gtgctgcggg tcaaggcgtc ccgcacgggt acggacacgg tgtcgctgac cgtggccgac
     1441 acctcgggcg gtctggtcgc cacgaccgga tcgctggcgc tgcggccggt gacgcgcgag
     1501 cagctggacg cggcgggcgg ctccggcagc cgtgccggtg actcgctgtt cggactcgcc
     1561 tggcagcccc tcgccctcac gcgggcaggt gccgcgctcg acgtgcggag ctacccgagc
     1621 gcgtccgctg tcttcgccga gccggacctg cccgatgtcg cggtcctcac ggttccgccg
     1681 tgcccggacg ggccggatac ggaggtcgcc gaccgcgtgc acggcatcgc gtgcgaggtg
     1741 ctggagctgg tgcagtggtg gtcggcgcgg gagggtgcgg gtcggctggc gttggtgacg
     1801 tccgcgggtg atctggcgca tgccgcggtg tgggggctgg tgcgttccgc gcagtcggag
     1861 aacccggacc ggttcgtgct ggtggaggcc gaggaggtcg gtgaggcggt ccgggtgctg
     1921 cccgcggtgc tcgcctccgg tgagccgcag ttcgcgctcc gtggcgggga ggtgttcgta
     1981 ccgcgcctgg tgaagacgcc gacggccgcc ccgggcggcg acgacggcct gccggacctc
     2041 atcgacggta ccgttctcgt gaccggtgcc tccggagcac tgggcgcact cgtcgcccgg
     2101 cacctggtgt ccgaacacaa ggcgcgcagg ctcctgttgg tgagccgccg tggcgcggac
     2161 gcgcccggcg cggccgagct gggggccgag ctggccgcgg agggcgccga catcacctgg
     2221 gcggcctgcg acgtcgcgga ccgggaggcg gtcgccgagc tgctgaccgg gctcggcgag
     2281 cacccgctgt ccgccgtcgt gcacaccgcg ggtgtgctgg acgacggagt cgtcgcttcg
     2341 gtcacgcccg aaaggctgcg gggagttttc cgtccgaagg tggacgccgt gctgaacctg
     2401 cacgagtgca ctcacggcat ggacctggcc gcgttcgtgg tgttctcctc cgtcgccggc
     2461 ctggtcggca gcgccggcca ggcgagctac gcggcggcga actccttcct cgacgccttc
     2521 tcggcgcacc ggcgccgggc gggactgccc gccacatcgc tggcatgggg cgtgtgggag
     2581 cagtccggtg cgatgaccga cggcctcgcc gaggccgacc gggcgcggat ggcgcgcagc
     2641 ggcgtgctgc cgctgccacc ggaggaaggg ctgcggctgt tcgacgcggc actcgtctcg
     2701 gacgaggccg tgctcgcccc ggtccgcatc gacaccggcg cgctgcgcgc cggtgaggcg
     2761 ccgccggtgc tgcggtccct ggtgccggcc atgaccgttc gcaggaccgc tcagaccgcc
     2821 gctgtctccg cgccctcgct ggccgaacgg ctggacgggc tgccggaggg cgagcgggag
     2881 aagaccgtgc tggacctggt ccgggccgag gtggccgcgg tcctggggca cgcgtcggac
     2941 cgtacggtcc gaccggagca cgccttccag gacctgggct tcgactccct gacggccgtc
     3001 gaactgcgca accggctgaa cagggccacc gggctgcggc tgcccgcgac gctggtcttc
     3061 gaccatccga cgcccgctct gctggcacgt catgtattta cagagacggc ggcggccgct
     3121 ccggctctag tggattccct acttgccgac ctggacaggg tcgaacaaga attggccacg
     3181 aagttgggag agggcgaagc tcgcgaccgg atcacgtcaa agctccagaa gcttctggcg
     3241 attaccgggg gattcggcac tgtgccggct cgggaaagcg cggacacggg cgagagcgat
     3301 ctggaatcag ccacggacga cgaagtattc gatctgctcg gcaaggaatt cgggatttcc
     3361 tgaccgcttg ggcatgccct ggtgacccct ttggtgaatt ccgctaagtc atcgcaggag
     3421 tgaggacgat ttcggtggcg aacgaggaca agctccgcta tttcctgaag cgagtcaccg
     3481 cggatctcca ggagacgcgg cggcgccttc gtgaccacga ggacgccgcc ggggagccgg
     3541 tggccatcat cgggatgagc tgccgctacc cgggcggtgt cgattcgccc gaggacctgt
     3601 ggaggctggt cgccggcggc cgcgacgccg tctcggagtt ccccaccgac cgcggctggg
     3661 acctggacgc gctctacgac ccggacccgg agtcacgggg caccagttac gcccgtgagg
     3721 gcgcgttcct gcaggacccg gcgcggttcg acgccagcct cttcggtatc tcgccgcgtg
     3781 aggcgctcgc catggatccc cagcagcggc tgctgctgga gacgtcgtgg gaactcttcg
     3841 aacgggccgg catcgacgcc gcctcgctgg cgggcagcag aaccggcgtg ttcaccggag
     3901 tgatgaacca cgagttcctc gccaccctcc agaacgcccc ggaggacctg gagggttacc
     3961 tggggacggg cacgtcgggc agtgtcgcct ccggccgggt ggcctacacc ttcggcctcg
     4021 aaggcccggc cgtcaccgtc gacacggcct gctcctcgtc cctggtggcc ctgcacctgg
     4081 ccgtccagtc gctgcgcagc ggcgagtgct cgctggccgt ggccgggggt gtcaccgcga
     4141 tggtcggccc cgccaccttc gtcggcttca gccgccagcg cggactggcg cccgacggcc
     4201 ggtgcaaggc gttcgccgcc ggtgccgacg gcaccggctg gggcgagggc gccggactcc
     4261 tgctcgtgga gcgcctctcg gacgcccgcc gcaacgggca cgacatcctc gcggtcgtcc
     4321 gcggctccgc cgtcaaccag gacggcgcgt ccaacggcct gaccgccccc aacggtccct
     4381 cccagcagcg ggtgatccgc caggccctgt ccgccgccag gctgaccgcg gcccaggtcg
     4441 acgtggtgga ggcgcacggc acgggcaccc ggctcggtga cccgatcgag gcgcaggcgc
     4501 tgctcgcgac gtacgggcag gcccgtaccg aggacaagcc gctgctgctg ggctcgatca
     4561 agtccaacat cggccacacc caggccgccg ccggtgtggc gggcgtcatc aagatggtca
     4621 tggcgatgcg caacggcgag ctgccgcgca cgctgcacgt cgacgcgccg tccccgcacg
     4681 tcgactggtc ggcgggcgcc gtacggctgc tcaccgagca cacgccctgg cccgcgtcgg
     4741 acgagccgcg ccgggccggt atctcctcct tcgggatcag cggcaccaac gcgcacacga
     4801 tcatcgagga ggccccgtcg gccgatgccc ccgccctgga cgccggggag gagccggcgg
     4861 agccggcgga aggcgaaggg aacacggaag ccctcgtccc ggaggccgcg cgcccggccg
     4921 aaggcggacc ggtgccgtgg gtggtctccg gccacacgga ggaggccctg cgcgcccagg
     4981 ccgaacgcct gctgtcccgc acggagtcgg aggtctcccc gtacgacgtg gcgttctcgc
     5041 tcgccaccac ccgcacggcc ctcgagcacc gggcggtggt ccagggcgga acgccggcgg
     5101 agctggccga ggggctgcgg gccgtggcct ccggctcccc ggccccgggc gtcgcgcgcg
     5161 gccggtcggg ctccggcggg cgcgtcggat tcctcttctc cggccagggg tcgcagcgcc
     5221 cgggcatggg ccgcgaactg tacgccgccc acccggcgtt cgccgccgca tacgacgagg
     5281 tctgcagcca cctcggcgcg gtcgtcgacg tggactcgga ggaactgcac cgcacgggcg
     5341 ctgcccagcc cgcactgttc gccgtcgagg tcgcgctgtt ccggctgctg gagtcgtggg
     5401 gtgtgcggcc ggactacgtg gccggtcatt cggtgggtga gatcgcggcc gcgcatgcgg
     5461 ccggggtgtt gtcgctggag gatgccgcga agctggtgtc ggcgcgggcc gcgctgatgc
     5521 aggcgttgcc cgagggcggc gcgatggtcg ccgtccaggc caccgaggac gaggtcctgc
     5581 cgcacctctc cgacggcgtc ggtgtcgcgg cggtcaacgg gccccgctcc gtggtcctct
     5641 ccggggccga ggccccggtg ctggaaatcg ccgagatctt cggccggcag ggccgcaaga
     5701 cctcccggct gaaggtgagc cacgcgttcc actcgccgct gatggagccg atgctggcgg
     5761 agttcggcga ggtcgtcgcc gggctggccc acgagcagcc gcggatcccg gtggtctcca
     5821 cgctcaccgg ccgcccggcg gagccgtaca cgcccgagta ctgggtccgg cacgtccgtg
     5881 agacggtgcg tttcgcggac ggcgcgcgga ccctgcacga gctgggcgtg accacgttcg
     5941 tggagatcgg ccccggcggt gtactgagcg gcctcaccca gggctgcctg gacgaggacg
     6001 tcgtcaccgt gcccgccctg cgcgccgacc gccccgagcg ggacgcactt gtcgccgcgg
     6061 tcgccgaact gcacgcgcac ggggtctccc ccgactggca cgccttcttc cccggtgccc
     6121 gccgtgtcga gctgcccacc tacgccttcc agtacgaccg ctactggctc gatgccgcac
     6181 cggccacctc cggtgacgtc cgcgccgcgg gcctgggcgc ggccgaccac ccgctgctgg
     6241 gcgcggccgt ctccctggcc ggcggcgacg agcggctgct gaccggcagg ctgtccctgc
     6301 gtacgcaccc gtggctgagc gaccacgccg tgctcggcac cgtgctcctg ccgggcaccg
     6361 cgttcgtcga gctcgccgtg cgcgccgccg acgaagccgg ctgcgacctg ctggaggacc
     6421 tcaccctcga agcgcccttg gtcatccccg agcagggcgg cgtcgcggtg caggtgtggg
     6481 tcggcgcggc cgacgattcc ggccgcaggc cgctgaccgt gcactcgcgc ccggaggagg
     6541 acgcccacct gccgtgggtc cgccacgcca ccggctccgt cgccgaggcg accgcggaga
     6601 cgggcgccgg ggccgccggg agcacgctcg cgacgtggcc gccggcgggc gccgaaccga
     6661 tcgccctgga cggcttccac gaccggctgg ccgccctcgg cctgtcctac gggccgacgt
     6721 tccgcggcct gcacagcgcc tggcgcgcgg gcgaggaagt gttcgcggag gcagccctcc
     6781 ccgagggcac ggacgcgggc tccttcctcc tgcacccggc gctgctggac gcgtcgctgc
     6841 acgcgatcgg cgcgggcgcc gcggacggct cccccggggc cgatgccgat gccgggtccg
     6901 gcgggccgct cctgccgttc gcctggtccg gggtgtccgt gcacgccacg ggcgcgtcca
     6961 ccgtacgggt caggctggcg ccggccggta cggacgcggt gtccctgacg gtcgccgacg
     7021 gcaccggcgc accggtggcg tcggtcgaat cgctcacgct ccgccccgtc tcggccgggc
     7081 agctgcgcaa gaactccggt gacgcactct tcaccgtcga gacggtgccg ctggccctgc
     7141 cctcggacgg agcggagggg acgacggtcc tctgggcgct ggacacggcc gtaccggccc
     7201 cgaccgacgg gccggcgcaa ccggacgtgg tcgtcgtccc cctccccgac ggcccggaag
     7261 gggcgaccgg ggccgagcgg gtccgcgcgg tcacctccgc gacactgcgg ctggtccagc
     7321 actggacggc cgaggagcgc acgccgcacc tcgtgctggt ggcccgctgc gacgacctcg
     7381 cgcacgccgc ggcgggcgcc ctggtgcgct ccgcccaggc ggagaacccc ggccggctca
     7441 cgctgctcga gacggaccgc ccggacgagg cggccgcgca ggcgtcaggc gtcgtgctgt
     7501 ccggcgaacc ccacgtcatc gtccgtggcg gggaagccgg cgtgccgcgg ctggtccgcg
     7561 ccgtaccccg gacgcccgag acggccaccg gccccaccgg cgaggcggct cccgcaccgg
     7621 tcggcggagc ctccggcggc ctcggcaccg tactcctcac cggagcctcc ggcgcgctcg
     7681 gtgaaacgct ggcccgccac ctggtcaccg cacacggcgt gcgccggctg ctgctggtca
     7741 gccgccgtgg cgcggacgcc ccgggtgccg tggacctacg ggctgagctc gccgcgctcg
     7801 gtgccgaagc ggagtgggcc gcctgcgacg tcgccgaccg tgacgccctc gcccggctgc
     7861 tggccgccgc cccggtcgac tccgtcgtgc acaccgccgg cgtcctggac gacggcgtga
     7921 tcgccgcgct gaccccggag cgcctggacg ccgtcctcgc gcccaaggcc gacgccgtgc
     7981 tcaacctgga cgaactcacg ggcgagcgca cgacgttcgt gctgttctcc tccgccgcgg
     8041 gtgtcttcgg aaactccggc cagggcaact acgccgcggc caacgccttc ctcgacgcct
     8101 tcgcccggca ccgccgcgcc cagggccggc ccacggtgtc gctggcctgg ggtctgtggg
     8161 agcagaaggg tgccatggcc gacgccctgg acgaggcggg caggacgcgg atggcgcgct
     8221 ccggtgtcct gccgctgtcc accgaggagg gtctgcggct gttcgacgcg gcgctcgcct
     8281 cggacgagcc ggtgttcgtg ccggtccgcc tcgacaccgc tgccctgcgc aaccgtacgg
     8341 cggagagcgt gccggccctg ctgcgcggac tcgtccgtgt ccccgcgcgc ggcacggccc
     8401 agcgcgccgt caccggatcc ctcgccgacc ggctcgccgg actggccgcg gacgagcgcg
     8461 acgaggcact tctggagctg gtccggagcg aggccgccgc cgtgctgggc cacacctccg
     8521 cccgggccgt ccagcccgcg cacgccttcc aggacctggg cttcgactcc ctgacggccg
     8581 tggaactgcg caaccgcctg tccaccgcca ccggtctgcg actgtccgcc accctggtct
     8641 tcgaccaccc cacgcccgcc gctctcgctc ggcacatcgg catcgaactc ctcggcgagg
     8701 ccccggcccc cgtgcccggc gccgccgcgg gagcgcgcac ggcggccggg accgacgagc
     8761 cgatcgccat cgtcggcatg agctgccgtc tgccgggcgg ggtgcgctcg ccggaggacc
     8821 tgtggacgct ggtggcctcc ggccgggacg gcatctcccg gttcccggag aaccgcggtt
     8881 gggacatcga ggggctctac gaccccgacc cggagcgcct cggcaggacc tacgcccgcg
     8941 acggtggctt cctccacgag gcggccgagt tcgacgccgg gttcttcggc atctcgccgc
     9001 gcgaggcgct ggcgatggac ccgcagcagc ggctgctgct ggaggcgtcc tgggaggcgt
     9061 tcgagcgcgc cgggatcgac ccggagacga tccggggcag ccgtacgggc gtcttcacgg
     9121 gcctgatgta ccacgattac ggccagggcc cgcgcgaact gcccgagggc gtcgagggcc
     9181 tgctcaccac cggaggctca ggcagtgtcg cctccggccg ggtgtcctac accttcggcc
     9241 tggagggccc cgccgtcacg atcgacacgg cctgctcctc gtcgctcgtc gctctgcacc
     9301 tggccgtcca ggccctgcgc aacggcgagt gcacgatggc gctggcgggc ggtgtcaccg
     9361 tcatggccac tcccacggtc ttcgtcgagt tcagccggca gcgcgggctg tcgccggacg
     9421 gccggtgcaa ggcgttcgcc gccggtgccg acggcaccgg ctggggcgag ggcgtcggca
     9481 tgctcctggt ggagcggctg tccgacgccg agcgcaacgg ccaccaggtg ctggcggtcg
     9541 tgcggggcag cgcggtgaat caggacggtg cgtcgaacgg tctgacggct cccaacggtc
     9601 ccgcgcagca gcgggtgatc cggcaggcgc tggcctcggc cgggctcacg ccgggcgacg
     9661 tggacgccgt cgaggcgcac ggcaccggta cgaggctggg tgacccgatc gaggcgcagg
     9721 cgctgctggc cacgtacggt caggagcggg cggacgggca gccgctgtgg ctggggtcgc
     9781 tgaagtccaa catcggccac acgcaggccg ccgcgggtgt cgccggtgtg atcaagatgg
     9841 tgatggcgct gcggcacggt gtgctgccga agacgctgca cgtggacgag ccgaccccgc
     9901 acgtggactg gtcggccggt gacgtgcggc tgctgaccga ggccgtcgac tggccggaga
     9961 cggaccgccc gcgccgggcc gccgtctcct ccttcggcgt cagcggcacc aacgcccaca
    10021 ccatcatcga gcaggccccc gccgcggcgg ccaccggcgg cacgccggca cccggctccg
    10081 gcaccgccgt gccctgggtg ctctccggca ggaccgagga ggccctgcgg gcgcaggccg
    10141 cccgcctcgc gtccttcgtg gacgaccacg acgccgcggc cggcgacggg gaagccgccc
    10201 tggtggccga cgtggcgtac tcgctggcca ccaccagggc cgccttcgag catcgcgccg
    10261 cggtcgtcgg gcacaccctg caggagatgc ggcagggact ggccgctgcc gcgagcggcg
    10321 acaccccgcc cggtgtggtg accggcgccg cacgcacccg cggcagaacc gtcttcgtcc
    10381 tccccggaca gggctcgcag tggatgggca tggccgccga actgctggag acctcccctg
    10441 tcttccgcga gcggatcgag gcctgcgagc gtgctttcgc accgcacgtg gactggtcgc
    10501 tgaccgaggt gctgcacggc accgccgagg ccgagcagga tcgggtcgac gtgctgcagc
    10561 cggtgctctg ggcgatgacg gtcgccctcg ccgaggtgtg gcgctcctac ggagtgatcc
    10621 ctgacgcggt cgtcgggcac tcccagggcg aggtctccgc ggcagtgatc gccggagcgc
    10681 tctccctgga ggacggtgcg cgcgtcgtgg cgcggcgcag cctcgccgtg cgcgaactcc
    10741 aggggcgcgg cgccatggcc tcggtgacgc tcccggacga ggaggcgcgg gaactggtcg
    10801 gccggtggga cggccgcctc ggcatcgccg ccgtcaacgg gcccgccacc gtcgtcgtct
    10861 ccggtgagac cggcgccatg gaggaactcc tcgcgcactg cgccgcggag aacgtccagg
    10921 cccgcaaggt ggccgtcgac tacgccgcgc actcacccca gatcgagctc gtcgaggagc
    10981 aggcgaggga gggattcgtc ggcatcagcc cgcttcccgc caccgtgccc ttctactcca
    11041 cggtgaccgg cgggaaactg gacccggccg aactcggttc cggctactgg taccgcaaca
    11101 tgcggcagac cgtgcggttc cacgacgcga tccgcgccgc gctggccgac gggcacgatg
    11161 tgttcatcga ggtcagcccg caccccgtgc agctgacggg tgtccaggac gccatcgagg
    11221 ccgccgacgc ggtcgccgcg gtcgtaccga cactgcgccg ccgcgacggc ggaatccacc
    11281 ggctgatgct ctccctggcc gaggcccacg ggcacggcgt cgccgtcgac tgggacgccg
    11341 tcctgccggg cgcgcgccgc gtcgacctgc cgacctacgc gttccggcac gagcggtact
    11401 ggctggaggc cggcgccccg gccggcgacg tgcgcacggc cggactcgac gccgccgacc
    11461 acccgttcct gggcgcggcc gtggaactgc cggacgccgg cggccacctg ctcaccggga
    11521 tgctctccct gcaggcccac ccctggctgg ccgaccacgc ggtgctgggc accgtcctgc
    11581 tgccgggcac ggccttcgtg gaactggccg cccacgccgc ggccgagacc ggctgcgacc
    11641 tggtcgagga actcaccctg caggcacccc tcgtactgcc cgagcacggc ggcgtcgcgc
    11701 tccaggtcct ggtcggcgcc caggacgact ccggccgccg gccgctgagc gtgcattcgc
    11761 gggccggtga cggaccctgg ttgcgcaacg ccaccggtgt cctcgccacc ggcgcgaccc
    11821 ccgccgagac cgacctcggt atctggccgc cggccgacgc gcagccggtg gacctggacg
    11881 acttctacgg ccggctggcg gacctcggcc tcagctacgg tccggccttc caaggactgc
    11941 gcgccgcctg gcgcggcaac gacgcggtct acgccgaact cgccgtggcc gacgggacgg
    12001 acaccgacgc gttcggcctg cacccggccc tgctcgactc cgcgctgcac gcactgggcg
    12061 cgggcggcct cgtaccggcc gccgacgggc ccctgctgcc cttcgcgtgg tcccgcgtca
    12121 ccctgcgcgg aaccggagcg gccgccctgc gggtgcggct cgccccggcc ggcggcgaca
    12181 ccgtacggct ggaggccgcc gacgacacgg gccgctccgt cgtgtcggtg gagtcgctga
    12241 cactgcgccc ggtgtcggtc gagcacctgc ggaccaactc ccgggacgcc ctgttcaccg
    12301 aggagtgggc accgctcgcc gccccgtcgg acgcgcccac cccgaccctg cgcttctacg
    12361 acgacacggc cgccctcctc gccgctcccg agacggagac gggggcggag gccgcgacgg
    12421 acgccgtcgt cgtcccctgc ccggccgggc agggcgccga cgccgaacgg ctccgcgacg
    12481 tcctcgccga ggtgctccgg ctcgtccagt ggtggctctc cgaggaccgc gcaccccgcc
    12541 tggtgctgtt gtcccggggc gcggtcgccg cgggggacgg cccggcgcag gacgacccgg
    12601 tgcacgcggc cgtgtggggc ctgatccgct cggcgcagtc ggagaacccg gaccgcgtcg
    12661 tcctcctcga cctcgacccc ggcctcggca tcgacgccgg cgccgaagcg gagcggaccg
    12721 cggcgaccgc cgtccgccgg ctcgtcgcct ccgaagagcc gcaggcggca ctgcgcggtg
    12781 acgtactcct gctgccccgg ctcgccaggg cggccaccga cgccccgcgg accggccccg
    12841 gcttcggaac cggcacggtc ctggtgaccg gcgcctccgg cgccctgggc agcctcgtcg
    12901 cccggcacct ggtcaccgag cacggagtgc gcagcctgct gctgctcagc cggcgcggcg
    12961 cgaccgccga cggcgcagcc gaactccagg cggaactgac cgccgcgggc gccgaggtgc
    13021 gctgggcggc ctgcgacgcg gccgaccggg acgccctcgc cgaggcgctg tccggcacgg
    13081 aagtgacggc cgtggtgcac acggccggcg tcctggacga cggtgtgatc gcctcgctca
    13141 ccccggagcg gctggagacg gtgctgcgcc ccaaggcgga cgcggtgctc aacctgcacg
    13201 aactggcggg tgacgtgtcc gcgttcgtgc tcttctcctc gctcgcgggc accctcggca
    13261 cgcccggcca ggccaactac gccgcggcca acgcatacct ggactccttc gcccggttcc
    13321 gccgggccca gggcctgccc gccgtgtcac tgccctgggg cctgtggcag cgcaccggtg
    13381 ccatgaccga ggacctcggc ggcaccgacc ggaaccggct ctcccgcggc ggcgtgctgc
    13441 ccttgtccga cgaggacggc ctggaactcc tcgacgccgc gctcacgctg gaagagcccc
    13501 tggtggtggc ggcacggctg gacctcgccg ccctacggaa cgctgccacc ccggtgcctc
    13561 cattgctcag ggcgctcgtc ggcggccggc cgcgccgtac cgaccgggcg gcctccgtac
    13621 cgctggcgca gcggatcgcg ggcctgcccg agagcgagcg cgcggaagcc gtactggacc
    13681 tcgtacggtc cgaggccgcc gccgtcctcg gacacagctc ggccaaggcc gtccaacccg
    13741 accacgcctt cggcgaactc ggcttcgact cgctgaccgc ggtggagctg cgcaaccgga
    13801 tgaaccgggc caccggactg cgcctgcccg cgacgctgat cttcgaccac ccgacgcccg
    13861 cggcgctcgc gcagcacatc ctcaaggacc tccccggcgg cgcggcgggg acggcacccg
    13921 tcttcgacga gctggaccgc ctggccgcgg ccctggacgg cgccggcgcg ggcgacgtcg
    13981 acaacgtcac ccggacccgg atcaacatgc gtcttcaggc gctgctcgcc cgctggaacg
    14041 gggacgggcc ggccgatgcg ggagacgacg gcacgaccgg gaccgggcac gacctcagct
    14101 cggcgagcga cgaggagctg tacgacctgc tcgatgacga actcggcatc tcctgaactg
    14161 ggcaaggcca caaaggggcg ggcaacatcg atgatgaacg aagacaagct ccgggactac
    14221 ctcaagcggg ccaccaccga cctgcggcag gcccggcggc gggtgcgcga gctggaggcc
    14281 ctcggccagg agccgatcgc catcgtgggc atgggctgcc ggttccccgg cggcgtcggc
    14341 tcccccgagg agctgtggcg gctgctggcc gagggcacgg acgccgtctc ggacttcccc
    14401 gacgaccgcg gctgggacct cgacgcgctc tacgaccccg accccgaccg gcccggcacg
    14461 gtctacaccc ggcagggcgg cttcctgcgt gacgcggccg acttcgacgc cgacttcttc
    14521 ggcatctcgc cgcgcgaggc gctggccatg gacccgcagc agcggctgct gctggagacg
    14581 tcatgggagg ccttcgagca cgcgggcatc gaccccgcgg atctgcgggg cagccgcacc
    14641 ggcgtcttcg ccgggctgat gtaccacgac tacggcttca cgcccggcgt cctccccgag
    14701 ggggtcgagg ggctgatgag caccggcaac tccggcagcg tcgcttccgg ccggatcgcc
    14761 tacaccttcg gcttcgaagg gcccgcggtc accgtcgaca ccgcctgctc gtcctccctc
    14821 gtcgccctgc acctcgccgt gcaggcgctg cgagccggcg agtgctccat ggcgctcgcc
    14881 ggcggcgtca cggtcatggc gggtccgagc gccttcgtgg agttcagccg ccagcgcggg
    14941 ctcgcccccg acggccgctg caagtccttc gcggccgcgg cggacggcgc gtcctggtcc
    15001 gagggcgccg gcctgctgct cgtggagcgg ctgcgggacg cccgccggct cggccaccag
    15061 gtgctcgcgg tggtccggag cagcgcggtg aaccaggacg gcgcgtccaa cggcctgacc
    15121 gcgcccaacg gtccctcgca gcaacgcgtg atcctcgaag cgctggccgg cgcccggctg
    15181 tccgccgagg aggtcgacgc cgtcgaggca catggcaccg gcacgcctct cggtgacccg
    15241 atcgaggcgc aggcgctgct ggcgacctac gggcaggagc gcgaccgccc gcttctggtg
    15301 ggctcgctga agtccaacat cggccacacg caggccgcgg cgggtgtcgc gggtgtgatc
    15361 aagatggtgc tggcgatgcg gcacggcgta ctgccgaaga cgctgcacgt ggacgagccc
    15421 accccgcggg tggactggtc ggccggctcg gtcgggctgc tgaccgaggc gaccgcgtgg
    15481 ccggctacga accgtcctcg ccgggcgggg gtctcgtcgt tcgggatcag cggcaccaac
    15541 gcgcacgtca tcctcgaaga ggcgccggtg gaggcgccgg aggaggcccc tcaggagcag
    15601 gcgcccgacc ccgagccggc ggccggggag gcggcggttc ctgccgggga gcggacgcgg
    15661 acgaaggccg cggtggtgcc gtgggtgctc tccgcgaaga ccggacaggc gctgcgggcg
    15721 caggcgcggc gactgctgtc gtccgtggac ctggccaccg cggcaccggc cgacgtggcg
    15781 ttctcgctgg ccgccaatcg ctcggcgctg gagcaccgcg cggcggtcgt cggcgccgac
    15841 gaggaggagc tgctcgccgg cctggccgcc cttgcggcgg gcgagcccgc ggcacaggtg
    15901 gtgacggggc gggccgcgtc cgaccagggc aaggtcggtt tcctgttctc gggtcagggt
    15961 tcgcagcggg tggggatggg gcgtgagctg tatgcggcgt tcccggtgtt cgcggcggct
    16021 tatgacgagg tgtgtgcgca tctcgatgtg gtgctcgacg tggacgagga ggagctgaac
    16081 cggacggggg cggcgcagcc ggcgttgttc gcggtggagg tggcgctgtt ccggctgctg
    16141 gagtcgtggg gtgtgcgccc ggactatgtg gccgggcatt cggtgggtga ggtcgcggcc
    16201 gcgcatgtgg cgggggtgtt gtcgctggag gatgccgcgg cgctggtgtc ggcgcgggcc
    16261 cggttgatgc aggcgctgcc ggagggcggg gcgatggttg cggtccaggc atccgaggag
    16321 gaggtgctgc cgcatctggc cgagggtgtg ggtgtcgcgg ccatcaacgg gccgcggtcg
    16381 gtggtggtct cgggtgccga ggcggtggtc ctcgccatcg gtgaggtgtt ccgggagcag
    16441 ggccgcaaga cctcccggct gaaggtgagt catgcgttcc actcgccgct gatggagccg
    16501 atgctggcgg agttcggtga ggtggtcgcc gggctgtcgt tcgagcagcc gcggattccg
    16561 gtggtgtcca acctcaccgg gcggctggtc gagtcgtaca cgccggagta ctgggtcgag
    16621 cacgtccgcg aggctgtccg cttcgccgac ggcatcgcga cgctgcacga gctgggtgtg
    16681 ggcacgtttg tggagatcgg gccggggggt gtcctgagcg ccctcgccca gggctgcttc
    16741 gacggcgacg cggacgtcgt caccgtgccc gtcctgcggg ccgaccgccc cgaggagcag
    16801 gccgtcgtca ccgccctcgc cgacctgcac gtgcacgggc acgaagtgga ctggcgcgcc
    16861 ttcttcccgg gtgcccgccg cgtcgacctg cccacctacg ccttccagcg cgagcgctac
    16921 tggctcgaag gcctggccgt gaccgacgtc tcctcggcag gcctggactc cgccggtcac
    16981 gccctgctcg gcgccgtggt ggagaccgcc gggacgcagg aggtgctgtt caccggccgg
    17041 ctgtccccgg ccgagctgcc ctggatcgcg gagcacaccg tcagtggcgt gccggtgctc
    17101 ccggtcgccg cgttcgtgga gctcgccctg tccgcgggcc ggcgtaccgg attcccgtac
    17161 ctgacccggc tcgacgtgga cgcccctctg gttctggccg aacacggtgc cgtccgcatc
    17221 caggtgcgga tcggcgtggc cgacgacccc gggcggcgct cggtgcgcgt cttcagccgg
    17281 tccgccgcgg ccggtaccgg tgaggcgtgg gtctgccaca ccaccgggga actgacccgg
    17341 gacgctccgg cgccggagct cgacctgacg gcttggccgc cggccggcgc ggaagcggtg
    17401 gacgtcgccg gccgcccggg cctgcgcgcc gcctggcgcg ccggggacga gctgtacgcc
    17461 gaggccgaac tgcccgccac ggagcggaat cgggcggacc gctacaccct gcaccccgta
    17521 ctcctggacg ccgccctcgg cctgatggcg ccggaccggg ccgcggaccc cggcgtgttc
    17581 cttctgcccc acgcctggag cggcatgtcc gtgcacacgc ccggacccgg cgccgtacgc
    17641 atacgcgtcc ggcccaccgg cgacgggacg gtggcgctcg agctgtccgg ggccgacggt
    17701 tctcccgtcg cctcggccac ctccgtccgg acccggacga tgaccgcgca gcaggtgctg
    17761 gcctcgcgcg tggcgcacca ggactggatg ttcgagatcg actgggtcga gcacaccgcg
    17821 gcccctgcca ccgcacccgc ctccggagcc ggctgggccg tactcggcga cgagggctcc
    17881 cacgcggaca tcggcgcgct ccgcgaggcg gtcgacggcg gtgcggccgt gcccgcccac
    17941 gtcctcctgc cctgcgcccc gagcgacggc gacgccgccg cggccacccg cgggacgctg
    18001 gccgaggtgt tgtcggccgt ccaggactgg gtcgccgacg agcggttctc cgacgcgcgg
    18061 ctcgtggtga tgacatgcgg aggcgccgga ccggacggcc cggcggtgga tcccgcgcac
    18121 gtcgcggtct ccggcctggt gaaggcggcc caggccgagc acccggaccg gctcctgctc
    18181 gtggacacgg atgattcgga cgactcgtcc tcgtacgacg gcacggaccc ggactcggcc
    18241 ggcggcctgg atccggcgct ggccgcggcg ctcgccgcgc tggacgagcc acaggccgcg
    18301 gtgcgcgacg gcaagctcct cgtgccgcgc ctcgcccgga tcagcccgcc cgcggagccc
    18361 gccggacccg cgtgggaccc cgagggaacc gtactgctca ccggtgcgac cggtggcctg
    18421 ggactgtcac tcgcgcggca cctcgtcgtc gaacgcggag cccgcaggct gctgctggcc
    18481 agccgccgcg gccccgcggc cgagggtgtc gcagagctcg tcaccgagct ctccgggctg
    18541 ggcgcgcacg tcgacgtggc cgcctgcgac atcgcggacc gccaagccct cgccgagctg
    18601 ctggcctcgg taccggctga gcatccgctg gtggccgtcg tgcacgcggc ggcggccctg
    18661 gacgacggtg tcgtcaccgc cctgaccccg gagcgtctgg acatcgtgct gcggccgaag
    18721 gtcgacggcg cgctgcacct gcacgagctg acgaaggacc tggacctgtc ggcgttcgtg
    18781 ctcttctcct ccctggccgg cgtcctgggc agcgcgggcg cggcgagcta cgccgccgcc
    18841 aacgccttcc tggacgggct ggcgcgccgg cgccgggccg cgggcctgcc cggcacctcg
    18901 ctggcatggg gcctgtggac ggacaacggc ggcatgggcg accggatcac cgacgccgac
    18961 cgcgaccgga tgggacggtc cggagtcgtg ccgttcaccc cggccgaggg actggccctg
    19021 ttcgacgccg ccctcaccgt ggaccggccg gtgctcgtcc cggtccggct ggacgtaccg
    19081 cagctgcgtg ccatggcccg cgccggcatg ctgcccgccg tcttccgcgg cctcgccggc
    19141 gacaccggct ccccggccga cgccgccgag ggaaccggcg ccacgcccct ggcggcccgg
    19201 ctcgccggaa tgccggaagc cgatcaggag aaggcactgc tggagctggt acgtcatcag
    19261 gcggcagcgg ccctcggcca cgtcgacgcc tcccgtgtcg agcccaccac cgccttccgc
    19321 gacatcggct tcgactccct gaccgccgtg gagctgcgca accggctcaa ggccgcgacc
    19381 ggcctgcggc tcaagcccac cctggtcttc gaccacccca accccgtcgc catcgcccgg
    19441 ctcctccaca aggacctgct gctggactcg gccgccgagg ccccgcccgt gctcgccgag
    19501 ctggaccggc tggaggagca gctcgccgct ctggccccgc aggacgcgct gcgggacaag
    19561 gtcaccgccc ggctcaaggc gctgctctgg aagtggaccg acacccgcca cgacgcggcg
    19621 gccgacgacg cgggccccgg caccggaagc gagctcgacc ggctcgacgc cgccaccgac
    19681 gacgagatgt tcgacctcat cgaccaagaa ctcggctccc tctgacctct gtcacgcact
    19741 gctaccgagg acgtaaaaca tgtcgaacga cgacaagctc agggactacc tcaagcgcgt
    19801 gatggtggac ctgcggcaga cccgcaggca gctgggtgag ctggaggcga aggacaccga
    19861 gcccatcgcc atcgtcggaa tggcctgccg ctacccgggc ggcgtcggct cccccgagga
    19921 cctgtggcag ctggtggcct ccggcggcga cggcgtgtcc gggttcccca ccgaccgcgg
    19981 ctgggacctg gacgccatcc acgaccccga gccggggaag acgggccgca cctacgtgcg
    20041 cgagggtggc ttcctccacg acgccggcga gttcgatccc gcgttcttcg gcatctcgcc
    20101 ccgtgaggcc ctggtcatgg acccgcagca gcggctgctc ctgcagacct cctgggaggc
    20161 cttcgaacgg gcgggcatcg accccgtcac cgcacgcggc agccggaccg gcgtgttcgt
    20221 cggcaccaac ggtcaggacc acgcctacct ccagcggccc gacgccgaca tcgaggccca
    20281 cctcgtcacc gcgaacaccg ccgccgtggt gtccggccgc atctcctacg ccctcggcct
    20341 cgaaggcccg gcggtcaccg tcgacacggc ctgctcctcc tcgctggtgg cgctccacct
    20401 ggccgcccag gcgctgcgcc gcggcgagtg ctcgctcgcc ctggccggcg gtgtcaccgt
    20461 gatggccacg ccgaacacct tcatcgcgtt cagcgcgcag cgtggcctgt cgcccgacgg
    20521 ccgctgccgc gcgttctcct cgaccgccga cggcacgggc atgtccgaag gcgtcggcgt
    20581 gctcctgctg gagcggctgt ccgacgcccg ccggctcggc cacgacgtgc tcgccgtcat
    20641 ccgcggcagc gcggtcaacc aggacggcgc ctccaacggc ctcacggccc cgaacggccc
    20701 gtcgcaggag cgtgtgatcc ggcaggcact ggagaacgcg cgcctcaccg cctcacaggt
    20761 cgacgcggtc gaggcgcacg gcacggccac caccctcggc gacccgatcg aggccgaggc
    20821 actgctcgcc acgtacggcc aggagcgtga ggacgaccgg ccgctgtggc tggggtccgt
    20881 caagtccaac ttcggccaca cgcaggcggc ctccggtgtc gccggtgtga tcaagatggt
    20941 gatggccatc cgcaacggcg tcctgccgca gacgctgcac gtggaggagc cgacggatca
    21001 ggtcgactgg tcctcgggcg gcgtcagact gctgaccgag gccgtccagt ggcccgagtc
    21061 cggccacccg cgccgcgccg ccgtctcgtc cttcggcgtg agcggcacca acgcccacac
    21121 gatcatcgag caggccccgg cctccgagga ggagcccgcc gccgaaccgg ccggcgcccc
    21181 ggttgccggc gcgctgccgt gggtactgtc ggcgaggagc gaggcggcac tgcgggccca
    21241 ggcgcagcgc ctgctctcct tcctcgagga cgaccgcggc ggttccggcc gttcaccggc
    21301 cgacatcggc ttctccctcg ccaccacccg caccgcctgg gaccgccggg cggccgtcgt
    21361 cggagagagc ccggaggcac tcaccgaagc cgtgagggca ctggcgtccg gcaccccgtc
    21421 ggcggccgtc gtccggaacg cggcccgcct cggtggcaag gtcggtttcc tgttctcggg
    21481 tcaggggtcg cagcgggtgg ggatggggcg tgagctg
//
