LOCUS       NZ_BMVW01000021        18725 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces poonensis strain JCM 4815 sequence21, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVW01000021
VERSION     NZ_BMVW01000021.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces poonensis
  ORGANISM  Streptomyces poonensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 113160)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 137X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650915.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:27:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,577
            CDSs (total)                      :: 7,501
            Genes (coding)                    :: 7,228
            CDSs (with protein)               :: 7,228
            Genes (RNA)                       :: 76
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 273
            CDSs (without protein)            :: 273
            Pseudo Genes (ambiguous residues) :: 0 of 273
            Pseudo Genes (frameshifted)       :: 96 of 273
            Pseudo Genes (incomplete)         :: 224 of 273
            Pseudo Genes (internal stop)      :: 19 of 273
            Pseudo Genes (multiple problems)  :: 60 of 273
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:46:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 18725
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVW01000021.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..18725
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..18725
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..18725
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[1914:8725](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(1915..8725)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(<1..176)
                     /locus_tag="IE242_RS33475"
     CDS             complement(<1..176)
                     /EC_number="1.17.7.3"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA]"
                     /GO_process="GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031167.1"
                     /locus_tag="IE242_RS33475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_189866167.1"
                     /transl_table=11
                     /translation="MTAVSLGVPGMPVRPLAERRLSRRIQVGPVAVGGGAPVSVQSMTT
                     TRTSDIGATLQQIA"
     gene            complement(181..1251)
                     /gene="hpnH"
                     /locus_tag="IE242_RS33480"
                     /old_locus_tag="GCM10010365_68700"
     CDS             complement(181..1251)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006139897.1"
                     /locus_tag="IE242_RS33480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_68700"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_189866169.1"
                     /sec_met_domain="PF04055 (E-value: 3.5e-20, bitscore: 65.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 6.2e-10, bitscore: 31.6,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQSLKVATYLAEQKLRGRDKFPLIVELEPLFACNLKCEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVARRKYVF
                     LCTNALLLRKKMDRFRPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVEAIKEAKKRGF
                     RVTTNSTFFNTDTPQTVVEVLDYLNDDLQVDEMMISPAYAYEKAPDQEHFLGVDQTREL
                     FRKAFAGGNRRRWRLNHSPLFLDFLEGKIDFPCTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRELIEETDWDSYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESLRAMRETVSPGNR
                     ISGERGSGERVSGNQG"
     gene            complement(1257..1904)
                     /locus_tag="IE242_RS33485"
                     /old_locus_tag="GCM10010365_68710"
     CDS             complement(1257..1904)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009998002.1"
                     /locus_tag="IE242_RS33485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_68710"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_229859779.1"
                     /transl_table=11
                     /translation="MPAEAPPGAPLLIACALGIERFALRGAGRGGPAGPVTVLRTGMGP
                     HAAGRSVTRALGDPALRGAAVLATGFCAGLAPDMHPGDLVVAARTRGPDGTVVPCVGTG
                     LLAGELRHAVPGRTVHTGLLTGSDHVVRGHERAALFRTGAIAVDMESGATLQCAVSAGA
                     HPVAAVRVVVDAPEHELVRIGTVRGGISAFRVLRSLLPAFFEWHRSLLLPRR"
     gene            complement(1915..3927)
                     /gene="shc"
                     /locus_tag="IE242_RS33490"
                     /old_locus_tag="GCM10010365_68720"
     CDS             complement(1915..3927)
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006133313.1"
                     /locus_tag="IE242_RS33490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_68720"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_189866172.1"
                     /sec_met_domain="T2TS (E-value: 3.5e-153, bitscore: 503.6,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSAGALPPRTASASDTDTDIDTPGAAGVPEAAVRAMRRA
                     TDLLLARQDAQGWWKGDLETNVTMDAEDLLLRQFLGIRDAETTRAAALFIRGEQRADGT
                     WTTFYGGPGELSTTIEAYVALRLAGDAPDAPHMARAARWIRDQGGIAASRVFTRIWLAL
                     FGWWRWEDLPELPPEIIWFPQWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLTE
                     LHTDPGDPRPARPLAAVTSWDGIFQRLDKVLHGYHRVASKRLRRVAMNTAARWIVERQE
                     NDGCWGGIQPPAVYSLIALHLLGYDLKHPVMRAGLESLDRFAVWREDGARMIEACQSPV
                     WDTCLATVALADAGVPADHPQLVRAADWMLGEEVLRAGDWAVRRPGLAPGGWAFEFHND
                     NYPDVDDTAEVVLALRRVRHPDPGRVDRAVGRGVRWTLGMQSRNGAWAAFDVDNTSPFP
                     NRLPFCDFGEVIDPPSADVTAHVVEMLAVEGRAHDPSTRRGIEWLLAAQEPNGSWFGRW
                     GVNYVYGTGSVVPALTVAGLPAAHPAIRRAVAWLETVQNDDGGWGEDLRSYEDVDGWSG
                     RGASTASQTAWALLALLAAGERESKTVERGIEWLVGTQREDGSWDEPYFTGTGFPWDFS
                     INYHLYRQVFPLTALGRYVHGEPFGDRTAAPQPGS"
     gene            complement(4098..5228)
                     /locus_tag="IE242_RS33495"
                     /old_locus_tag="GCM10010365_68730"
     CDS             complement(4098..5228)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008744686.1"
                     /locus_tag="IE242_RS33495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_68730"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_189866174.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 5.1e-58, bitscore:
                     189.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVVRHAADTRTPRPATRGETVPTVPPAPTAADAVDVTALLERGR
                     TLSTPVLRTAVGRLAPPMDTVASYHFGWIDAAGNPAEGDGGKAVRPALAVLSAEVTGAA
                     PETGIPGAVAVELVHNFSLLHDDLMDGDEQRRHRDTVWKVHGPAQAILVGDALMALANE
                     LLLELGTVEAGRATRRLTTATRALIDGQAQDISYENRDRVSVEECLEMEGNKTGALLAC
                     ASSIGAVLGGADDATADALESYGYHLGLAFQAVDDLLGIWGDPVSTGKQTWSDLRQRKK
                     SLPVVAALAAGGPASAKLGEILAADARSSDFASFSEEEFAARAALIEQAGGREWTAEEA
                     RRQHRIALDALDTVSMPERVREQFVALADFVVVRKR"
     gene            complement(5225..6724)
                     /gene="hpnE"
                     /locus_tag="IE242_RS33500"
                     /old_locus_tag="GCM10010365_68740"
     CDS             complement(5225..6724)
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018568730.1"
                     /locus_tag="IE242_RS33500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_68740"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_189866176.1"
                     /sec_met_domain="DAO (E-value: 8.2e-11, bitscore: 34.7,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDGTRTGGGTSADGRTAVVVGGGLAGITAALSLADAGVRVTLLE
                     GRPRLGGLAFSFRRGELTVDNGQHVYLRCCTAYRWFLDRIDGAALAPLQDRLDVPVLDA
                     AARPGRRLGRLRRDALPVPLHLGRSLATYPHLSLAERANAVRAALALKALDLADPALDE
                     RDFGSWLAAHGQSARAVEALWDLVGVATLNAVAQDSSLALAAMVFKTGLLSDPGAADIG
                     WARVPLGDLHDGLARRALDAAGVRTELRTRVTSVSPAANGRWTVEVPGERLDADAVVLA
                     VPQRETHGLLPAGALDAPERLLDIGTAPILDIHVVYDRKVLGKPFFAALGSPVQWVFDR
                     TEASGLREGQYLALSQSAAQDEIDTPVATLRERYLPELERLLPAVRGAGVRDFFVTRER
                     TATFAPAPGVGRLRPGARTKAPGLCLAGAWTATGWPATMESAVRSGISAADAALDALGR
                     PRDHLFDFGGEAAGRAFPGADPRTPGRVPEGAGVPLRGGPR"
     gene            complement(6721..6876)
                     /locus_tag="IE242_RS39360"
     CDS             complement(6721..6876)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039420.4"
                     /locus_tag="IE242_RS39360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6380 family protein"
                     /protein_id="WP_373299649.1"
                     /transl_table=11
                     /translation="MDNPVQGDSTTGGTSGGKRYATLRPRAASLTPTAWREPFKCHRPA
                     AGEGAR"
     gene            complement(6876..7826)
                     /gene="hpnD"
                     /locus_tag="IE242_RS33505"
                     /old_locus_tag="GCM10010365_68750"
     CDS             complement(6876..7826)
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972236.1"
                     /locus_tag="IE242_RS33505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_68750"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_189866177.1"
                     /sec_met_domain="phytoene_synt (E-value: 2.4e-56, bitscore:
                     183.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 3.9e-69,
                     bitscore: 225.8, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTVEPDARVSAPVLAAYSYCEAVTGQQARNFAYGIRLLPTAKR
                     RAMSAVYAFSRRVDDIGDGALTPEVKAARLEDTRALLTRVRDGAVDEDDTDPVAVALAH
                     ASGQFPIPLGGLDELIDGVLMDVRGETYETWDDLKLYCRCVAGAIGRVSLGVFGTEPGA
                     RGAERAAEYADTLGLALQLTNILRDLREDAEGGRTYLPADDLAKFGCSAGFAGPVPPRD
                     SDFIGLVHFEVRRARALFAEGYRLLPLLDRRSGACVAAMAGIYRRLLDRIEREPEAVLR
                     GRVSLPGREKAYVAVRGLSGLDARHVSRRTVRRRA"
     gene            complement(7823..8725)
                     /gene="hpnC"
                     /locus_tag="IE242_RS33510"
                     /old_locus_tag="GCM10010365_68760"
     CDS             complement(7823..8725)
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010042802.1"
                     /locus_tag="IE242_RS33510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_68760"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_189866179.1"
                     /sec_met_domain="phytoene_synt (E-value: 6.4e-41, bitscore:
                     133.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.9e-41,
                     bitscore: 134.9, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKAGTAYPGDREQGTLAKAAAENFPVAPFFLPRAWRDDLMAVYG
                     FARLVDDIGDGDLAPGGADARLLGVSSAAAEDRLVLLDAFEADLRRVFDGTPRHPLLRR
                     LQPTVRRRSLTPEPFLGLIAANRQDQLVTRYETYDDLLAYCELSANPVGRLVLGITGTS
                     TPERERRSDAVCTALQIVEHLQDVAEDLGRDRIYLPAADMKRFHVEEADLAAPTAGASV
                     RALVAYEAQRARDLLDEGIPLVGSVHGRLRLLLAGFVAGGRAAVDAIAAAAYDVLPGPP
                     KPGKLRLLREVGLTLREEG"
     gene            complement(9141..9917)
                     /locus_tag="IE242_RS33515"
                     /old_locus_tag="GCM10010365_68770"
     CDS             complement(9141..9917)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005484611.1"
                     /locus_tag="IE242_RS33515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_68770"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_189866181.1"
                     /transl_table=11
                     /translation="MAEARVPTVIADELHIVYRVNGARTGKGSATAALSRILKRGSDDT
                     ARGVRKVHAVKGVSFVAYRGEAIGLIGSNGSGKSTLLRAIAGLLPAERGKVYTDGQPSL
                     LGVNAALMNDLTGERNVILGGLAMGMSREQIRERYQEIVDFSGINEKGDFITLPMRTYS
                     SGMAARLRFSIAAAKDHDVLMIDEALATGDRAFQKRSEARIRELRKQAGTVFLVSHNNK
                     SIRDTCDRVLWLERGELRMDGPTEEVMKEYEKFTGK"
     gene            complement(9910..10839)
                     /locus_tag="IE242_RS33520"
                     /old_locus_tag="GCM10010365_68780"
     CDS             complement(9910..10839)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994380.1"
                     /locus_tag="IE242_RS33520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_68780"
                     /product="ABC transporter permease"
                     /protein_id="WP_189866183.1"
                     /transl_table=11
                     /translation="MSETTHDGGVAVSDRPSPDDGMTAAELAAKYGLSVSGARPGLVEY
                     VRQLWGRRHFILAFSQAKLTAQYSKAKLGQLWQVATPLLNALVYFLIFGLILNADRGMG
                     REIYIPFLVTGVFVFTFTQSSVMAGVRAISGNLGLVRALHFPRASLPISFSLQQLQQLL
                     FSMIVLFAVAIGFGSYPRLSWLLIVPVLVLQFCFNTGLAMIFARLGSKTPDLAQLMPFV
                     MRTWMYASGVMFSIPVMLADHPGWISDVLQWNPAAIYMDLMRFALIDGYGSANLPPHVW
                     AVAGGWAAVVAVGGFVYFWKAEERYGRG"
     misc_feature    10855..10869
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.42"
                     /tool="antismash"
     gene            complement(10937..11809)
                     /locus_tag="IE242_RS33525"
                     /old_locus_tag="GCM10010365_68790"
     CDS             complement(10937..11809)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031159.1"
                     /locus_tag="IE242_RS33525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_68790"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_189866331.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 7.8e-14,
                     bitscore: 44.6, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVGAVIITMGNRPEELRALLDSVAKQEGDRVQVVVVGNGSPVPE
                     VPEGVRTVELPENLGIPGGRNVGIEAFGPGGSDVDILLFLDDDGLLARNDTAELCREAF
                     AADPELGIISFRIADPETGVTQRRHVPRLRASDPMRSSRVTTFLGGANAVRTKVLAEVG
                     GLPDEFFYAHEETDLAWRALDAGWMIDYRADMVLYHPTTAPSRHAVYHRMVARNRVWLA
                     RRNLPVLLVPVYLGVWLLLTLLRKPSGPALKAWLGGFKEGWTSPCGPRRPMRWRTVWRL
                     TRLGRPPVI"
     gene            complement(11827..12606)
                     /locus_tag="IE242_RS33530"
                     /old_locus_tag="GCM10010365_68800"
     CDS             complement(11827..12606)
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049651.1"
                     /locus_tag="IE242_RS33530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_68800"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_189866184.1"
                     /transl_table=11
                     /translation="MQKPSVAELRPVVHPAGVKDRRSGEHWAGRLYMREISLRIDRHLV
                     NTRVTPNQLTYLMTLFGVLAAPALLVPGIWGAVLGVVAVQLYLLLDCVDGEIARWKKQY
                     SLAGVYLDRVGAYLCDAAVLVGFGLRAADLWGTGRIDWLWAFLGTLAALGAVLIKAETD
                     LVGVARHQTGKPPVQESASAPRSSGLALARRAASALQFHRLVLGIEASLLILVLAIVDT
                     ARGDLFFSRLGVAVLAGIALLQTVLHLVSILASSRLK"
     gene            complement(12584..13645)
                     /locus_tag="IE242_RS33535"
                     /old_locus_tag="GCM10010365_68810"
     CDS             complement(12584..13645)
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494151.1"
                     /locus_tag="IE242_RS33535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_68810"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_189866186.1"
                     /sec_met_domain="Fe-ADH (E-value: 6.9e-23, bitscore: 73.7,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPIVVDIRPGALDDLATVLADQRISSSGKLAVAISG
                     GSGAKLRERICPALPDADWFEVGGGTLDDAVQLADAMKRGRYDAVVGLGGGKIIDCAKF
                     AAARVGLPLVAVATNLSHDGLCSPVATLDNDAGRGSYGVPNPIAVVIDLDVIREAPVRF
                     VRSGIGDALSNISAVADWELAAREKGEDIDGLAAAMARQAGEAVLRHPGGVGDDGFLQV
                     LAEGLVLTGISMSVAGDSRPASGACHEINHAFDLLFPRRAASHGEQCGLGAAFAMYLRG
                     AHEESAYMAEVLHRHGLPVLPEEIGFTVDEFVQVVEFAPQTRPGRYTILEHLDLNTDQI
                     RDAYADYAKAIGS"
     gene            complement(13633..14385)
                     /locus_tag="IE242_RS33540"
                     /old_locus_tag="GCM10010365_68820"
     CDS             complement(13633..14385)
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983099.1"
                     /locus_tag="IE242_RS33540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_68820"
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="WP_189866188.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 8.4e-11, bitscore:
                     35.1, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVGPEGDEESLTVLDLTLG
                     NFAEIGLTEVAIIVGYRKEAVYERREALEQKYGVKITLIDNDKAEEWNNAYSLWCGRDA
                     VKHSVILANGDTVHPVSVEKTLLAARGDGKRIILAIDTVKSLADEEMKVVVDAEKGMTK
                     ITKLMDPAEASGEYIGVTLIEGEAADELADALKTVFETDPQQFYEHGYQELVNRGFKID
                     VAPIGDVKWVEIDNHDDLAKGREIACQY"
     gene            complement(14382..16199)
                     /locus_tag="IE242_RS33545"
                     /old_locus_tag="GCM10010365_68830"
     CDS             complement(14382..16199)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996269.1"
                     /locus_tag="IE242_RS33545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_68830"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_189866329.1"
                     /transl_table=11
                     /translation="MSTAILTGQPVPGASLEGELRALGFDVRVASDAGDAETLLARIPG
                     DQRVALVDARFVGHLHALRLGLTDPRFPVAALPGAVTVQPAARQALTRALARTGSRASG
                     DGGSGGSAVAVDGVAAALAADGVPVHRPELGSLVATVPADPQARNEARQAVAAVDDEAV
                     RLRTAVKSRDGFFTTYFVSPYSRYIARWCARRGLTPNQVTTASLLTALIAAGCAATGTR
                     GGFVAAGALLIASFVLDCTDGQLARYSLQYSTLGAWLDATFDRAKEYAYYAGLALGAAR
                     GGDDVWALALGAMILQACRHVVDFSFNEANTRDPAAAADASPAAALSGKLDRVGWTVWL
                     RRMIVLPIGERWAMIAVLTALTTPRITFYALLIGCGLAGLYTTAGRVLRSLTRRAQRTE
                     RAARALADLADSGPLAEVLARLLPSGPRVPARLLTVAGAAVVVLAAWFDGPGWSVVVCA
                     GVYVLVSADVIQHPLKGALDWLVPPLLRAAEYLTVLILAAKADVNGVLPAAFGLVAAVA
                     YHHYDTVYRIRGDAGAPPHWLVRAIGGHEGRTLLVTVLAALLTATGFKVALTVLAVAVA
                     LVVLFESIRFWVTAHRRGAPAVHDEGEPA"
     misc_feature    complement(16298..16312)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.45"
                     /tool="antismash"
     misc_feature    16320..16335
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.98"
                     /tool="antismash"
     misc_feature    16802..16813
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     misc_feature    complement(16891..16905)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            16982..17920
                     /locus_tag="IE242_RS33550"
                     /old_locus_tag="GCM10010365_68840"
     CDS             16982..17920
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009339288.1"
                     /locus_tag="IE242_RS33550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_68840"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_189866190.1"
                     /transl_table=11
                     /translation="MGAGHDHGHAHGAPAGGTATAAYRGRLRVALSITLTVMVVEIVGG
                     IVADSLALIADAAHMATDALGLGMALLAVHFAGRPANERRTFGYARAEILAALANCLLL
                     LGVGGYVLYEAIQRFLTPAATEGGLTIVFALIGLVANMISLTLLARGQQESLNVRGAFL
                     EVAADALGSVAVLVSAVVVLTTGWQAADPIASLVIGLMIVPRTVKLLRETLDVLLESAP
                     KGVDMAELRAHILALPGVEDVHDLHAWTITSGMPVLSAHVVVGSDTLSAIGHEKMLHEL
                     QGCLGDHFDVEHCTFQLEPSGHAEHEAKLCH"
     gene            17952..18491
                     /locus_tag="IE242_RS33555"
                     /old_locus_tag="GCM10010365_68850"
     CDS             17952..18491
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018100157.1"
                     /locus_tag="IE242_RS33555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_68850"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_373299650.1"
                     /transl_table=11
                     /translation="MHVLTDTPSEPIPSWRTRPEAAGDRAEVHALTVAAFGRAEEADLV
                     DALRGDAGAWLDLASVAEAPDGSVVAYALLTRCHVDEAPALALAPVAVRPDRQREGAGA
                     AVVRAVLAEARARGERLVLVLGHPEYYPRFGFAPASAYGIRPGFEVPDEAMMALVLDGS
                     PSVAPGTIVYPAAFGV"
ORIGIN
        1 gcgatctgct gcagcgtcgc gccgatgtcc gacgtacgcg tcgtcgtcat cgactggacc
       61 gagacagggg cgcctccacc gacggcgacc gggccgacct ggatccgccg cgacaggcgg
      121 cgttccgcga gcggccggac gggcatgccg gggacaccca gggagacggc cgtcatgaca
      181 tcacccctgg tttccggaga cccgttcgcc ggagccccgt tcgccggaga tccggttccc
      241 gggcgagacc gtctcgcgca tcgcgcgcag ggactccttc agggatccca tggtggccag
      301 gacggcggtg ggctcgtagc cgcagtgcgc catgcagttg gcgcagcgcg ggtccttgcc
      361 gcggccgtag ctgtcccagt cggtctcctc gatcagctcc cggtacgtcg gcacatagcc
      421 gtcgctcatc aggtaacagg gccgctgcca gccgaagagc gagtagttgg ggatggccca
      481 ggccgtgcac gggaagtcga tctttccttc caggaagtcg aggaacagcg gtgagtggtt
      541 gagccgccag cggcgccggt tgccgcccgc gaaggccttc cggaacagtt cgcgggtctg
      601 gtccacgccg aggaagtgct cctggtcggg cgccttctcg taggcgtagg cgggggagat
      661 catcatctcg tcgacctgga ggtcgtcgtt gaggtagtcg agcacctcga cgacggtctg
      721 cggggtgtcg gtgttgaaga aggtggaatt ggtggtgacc cggaagccgc gcttcttggc
      781 ctccttgatg gcctccacgg cctcgtcgaa gacgccctcc ttcgccacgg actcgtcgtg
      841 ccgctcacgc agcccgtcga tgtggacggc gaaggcgaag tacggcgagg gcctgaaccg
      901 gtccatcttc ttacggagaa ggagcgcgtt ggtgcacagg aagacgtatt tcctcctggc
      961 caccagctgt cgcacgatct cgtcgatctg agggtgcatc aggggctcac cgccggcgat
     1021 cgacaccatc ggcgcgcccg actccagcac ggctcccacg gcctgggcga ccggcatgcg
     1081 ctgcttgagc acacccgccg ggtgctggat cttgccgcag ccctcgcact tcaggttgca
     1141 cgcgaagagc ggttccagtt cgacgatgag cgggaacttg tcccgtccgc ggagcttctg
     1201 ttcggcgagg tacgtcgcca ccttgaggga ctggcggagt ggcatggcca tctggctcac
     1261 ctcctgggga gcagcaagga acggtgccat tcgaaaaaag cggggagaag ggaacgaagg
     1321 acacggaaag ccgatattcc accgcgcacc gtgccgatcc ggaccagttc atgttctgga
     1381 gcgtccacga ccacccggac ggccgcaacg gggtgtgcgc ccgcgctcac ggcgcactgg
     1441 agcgtggcac cggattccat gtcgaccgcg atcgcgccgg ttctgaacag tgccgcccgc
     1501 tcgtgtccgc gtacgacgtg gtcggagccg gtgagcagtc ccgtgtggac cgtacgtccc
     1561 ggcacggcat gccgcagctc ccccgccagc aggccggtgc ccacacacgg gacgacggtg
     1621 ccgtccgggc cacgggtgcg ggccgcgacg accaggtcac cggggtgcat gtccggggcg
     1681 agcccggcgc agaacccggt ggcgaggacg gccgcgccgc gcagcgccgg gtcgccgagc
     1741 gcccgggtga ccgagcgccc ggcggcgtgc ggacccatgc cggtgcgcag cacggtgacc
     1801 gggcccgcgg ggccgccgcg gccggcaccg cgcagggcga agcgctcgat gccgagcgcg
     1861 caggcgatca gcagcggagc cccgggcggg gcctcggcgg gcacgccgcc cacctcagct
     1921 ccccggctgc ggcgcggccg tcctgtcgcc gaacggctcg ccgtggacat accggccgag
     1981 cgcggtcagc gggaacacct gccggtagag gtggtagttg atcgagaagt cccaggggaa
     2041 gccggtcccg gtgaagtagg gctcgtccca ggagccgtcc tcccgctggg tgcccacgag
     2101 ccactcgatc ccgcgctcca cggtcttgga ctcccgctcc cccgccgcca gcagcgcgag
     2161 cagcgcccag gccgtctggg aggccgtgga ggcgcccctg ccgctccacc cgtccacgtc
     2221 ctcgtaggag cgcaggtcct cgccccagcc gccgtcgtcg ttctgcacgg tctccagcca
     2281 ggccacggcc cgccggatcg cggggtgcgc ggcgggcagc ccggcgacgg tcagcgcggg
     2341 caccaccgac ccggtgccgt agacgtagtt gacgccccag cgcccgaacc acgagccgtt
     2401 cggctcctgt gcggccagca gccactcgat gccccgccgg gtgctcgggt cgtgtgcgcg
     2461 cccttcgacg gcgagcatct ccaccacgtg cgcggtgacg tcggcggacg gggggtctat
     2521 cacctcgccg aagtcgcaga acggcagccg gttggggaac gggctggtgt tgtcgacgtc
     2581 gaaggcggcc caggcaccgt tcctcgactg catgccgagc gtccagcgca ccccgcgccc
     2641 gacggccctg tccacccgcc cggggtcggg gtgccggaca cggcgcaggg cgaggacgac
     2701 ctcggcggtg tcgtcgacgt cggggtagtt gtcgttgtgg aactcgaacg cccagccgcc
     2761 cggggcgagt ccgggcctgc gcaccgccca gtcgccggcc cgcaggacct cctcgccgag
     2821 catccagtcc gcggcccgca ccagctgcgg gtggtcggcg ggcactccgg cgtcggcgag
     2881 cgcgacggtg gcgaggcagg tgtcccacac cggcgactga caggcctcga tcatccgggc
     2941 gccgtcctcg cgccacaccg cgaaccggtc cagggattcc agaccggcgc gcatcacggg
     3001 atgcttcagg tcgtagccga gcaggtgcag cgcgatgagc gagtagacgg ccgggggctg
     3061 gataccgccc cagcagccgt cgttctcctg ccgctccacg atccagcgcg ccgcggtgtt
     3121 catcgcgacc ctgcgcagcc gcttcgacgc caccctgtgg tagccgtgca ggaccttgtc
     3181 gagccgctgg aagatcccgt cccagctcgt caccgccgcg aggggccggg ccgggcgggg
     3241 gtcgccgggg tcggtgtgca gctccgtcag cgggaagggc gcgggccgca cgggccgctt
     3301 cgcggagacg acggtgagcg gcacgatggt ctgccgtgcc cagcagccga agtcgtagat
     3361 gttgaggggc acccactggg ggaaccagat gatctccggc gggagttcgg gcaggtcctc
     3421 ccaccgccac cagccgaaca gggccagcca gatccgggtg aacacgcgcg aggccgcgat
     3481 gcccccctgg tcgcggatcc accgcgcggc ccgcgccatg tgcggcgcgt ccggggcgtc
     3541 cccggccagg cgcagcgcga cgtacgcctc gatggtggtg gagagctctc cgggtccgcc
     3601 gtagaaggtg gtccaggtgc cgtcggcgcg ctgctcgccg cggatgaaca gggcggccgc
     3661 gcgggtggtc tccgcgtcgc ggatgccgag gaactggcgg agcagcaggt cctcggcgtc
     3721 catggtgacg ttggtctcca ggtcgccctt ccaccagccc tgggcgtcct ggcgggcgag
     3781 cagcaggtcg gtggcgcgcc gcatcgcgcg gacggcggcc tccgggaccc ctgccgcccc
     3841 gggggtgtcg atgtcggtgt cggtgtcgct ggccgaggcg gtgcggggcg gcagggcccc
     3901 ggcacttccg tcggtcgtcg ctgtcatggc ttccccttcg tgcagtggct gtctctgctt
     3961 gtgggtccgc cgtcggccgg tgctggtgtg cggtgggagc ccctgcccgg gcgaggccga
     4021 gacttgtcga ggggcaccgg ccggcgacta cgcgaggctt attcgaccga taacgatcag
     4081 ctctttcgcg ttggtgatca tctctttcgt acgacaacga agtcggcgag tgccacgaac
     4141 tgctcccgca cccgctccgg catggagacg gtgtccaggg cgtcgagcgc gatccggtgc
     4201 tggcggcgcg cctcctcggc ggtccactcc cggccgccgg cctgttcgat gagggcggcg
     4261 cgggcggcga actcctcctc ggagaagctc gcgaagtcgc tgctccgcgc gtcggcggcg
     4321 aggatctcgc cgagcttcgc ggaggccggg ccgcccgccg cgagcgcggc cacgaccggc
     4381 agggacttct tgcgctggcg cagatcgctc caggtctgct tgccggtgga gaccgggtcg
     4441 ccccagatgc ccagcaggtc gtccacggcc tggaaggcga ggccgaggtg gtagccgtag
     4501 ctctccagcg cgtcggccgt ggcgtcgtcg gcgccgccga ggaccgcgcc gatggaggag
     4561 gcgcaggcga gcagggctcc ggtcttgttg ccctccatct ccaggcactc ctcgacgctg
     4621 acgcggtcgc ggttctcgta ggagatgtcc tgggcctggc cgtcgatgag ggcgcgggtg
     4681 gcggtggtga ggcggcgggt ggcgcggccg gcctcgacgg tgccgagctc caggagcagc
     4741 tcgttggcca gcgccatgag ggcgtcgccg acgaggatgg cctgggcggg gccgtgcacc
     4801 ttccacacgg tgtcgcggtg gcggcgctgt tcgtcgccgt ccatcaggtc gtcgtgcagc
     4861 agggagaagt tgtgcaccag ttcgaccgcg accgcgccgg ggatgccggt ctccggcgcg
     4921 gccccggtga cctcggcgga cagcacggcg agcgcgggcc gcaccgcctt gccgccgtcg
     4981 ccctcggcgg ggttgcccgc ggcgtcgatc cagccgaagt gatagctggc gacggtgtcc
     5041 atgggcggtg ccagacggcc cacggccgtc cgcagcaccg gtgtggacag ggtccggccg
     5101 cgctccagga gcgcggtcac gtccaccgcg tcggcagccg tcggggccgg gggcacagtg
     5161 ggcacagttt ctcctcttgt tgcggggcgg ggggtgcggg tatccgccgc gtgccgtacg
     5221 accgtcaccg gggtccacct cgcaggggga cgccggctcc ctcgggtact cggccggggg
     5281 tccgggggtc ggcccccggg aaggcccggc cggccgcctc gccgccgaag tcgaagaggt
     5341 ggtcccgggg ccggcccagg gcgtccagcg cggcgtccgc cgcgctgatg ccgctgcgga
     5401 ccgcactctc catggtcgcg ggccaccccg tggcggtcca cgctccggcc agacagaggc
     5461 cgggggcctt ggtacgggcg ccgggccgca gccgtccgac gccgggcgcg ggagcgaacg
     5521 tcgccgtgcg ctcccgggtc acgaagaagt cccgcacccc ggccccgcgc acggcgggca
     5581 gcagccgctc gagctccggc aggtaccgct cgcgcagggt ggcgacgggc gtgtcgatct
     5641 cgtcctgggc ggccgactgg gacagcgcca ggtactggcc ctcgcgcagc ccggacgcct
     5701 cggtccggtc gaacacccac tgcaccgggc tgcccagcgc cgcgaagaac ggcttgccca
     5761 gcaccttccg gtcgtagacg acatggatgt cgaggatggg cgcggtaccg atgtcgagga
     5821 gccgctccgg ggcgtcgagc gcgcccgcgg gcagcaggcc gtgcgtctcg cgctgcggta
     5881 cggcgaggac gaccgcgtcc gcgtcgaggc gctctccggg gacctcgacc gtccaccgcc
     5941 cgttcgccgc cggggagacg gaggtgacgc gggtgcgcag ctcggtacgg acgcccgccg
     6001 cgtcgagcgc cctgcgggcc agcccgtcgt gcagatcgcc cagcgggacg cgcgcccagc
     6061 cgatgtcggc cgcgcccggg tcggagagca gcccggtctt gaacaccatc gcggcgagcg
     6121 cgagggagct gtcctgtgcc accgcgttga gggtggcgac tcccaccagg tcccagagcg
     6181 cctccacggc gcgcgccgac tggccgtgcg cggccagcca gctgccgaag tcccgttcgt
     6241 ccagcgcggg atcggcgagg tcgagcgcct tgagcgccag ggcggcgcgg accgcgttgg
     6301 cgcgctcggc gagggagagg tgcggatagg tcgcgaggga acgcccgagg tgcagcggta
     6361 cgggcagcgc gtcgcgccgc agccggccga gccgtcgccc gggccgggcg gcggcgtcga
     6421 ggacgggcac gtcgagacgg tcctgcagcg gggcgagcgc ggccccgtcg atccggtcga
     6481 ggaaccagcg gtaggcggtg cagcagcgca ggtagacgtg ctgcccgttg tcgacggtca
     6541 gttcgccgcg ccggaaggag aaggcgagtc cgccgagccg cggccgcccc tccagcagcg
     6601 tgacccgcac cccggcgtcg gccagtgaca gcgcagcggt gatcccggcg agtccgccgc
     6661 ccaccaccac ggccgtgcgc ccgtcagcgg acgtgcctcc tccggttcgt gtgccgtcgg
     6721 tcatcgcgcg ccctcccccg cggccggacg gtgacacttg aacggttcac gccaggccgt
     6781 cggagtcagg gacgcggccc gcggccggag ggttgcgtac cgtttccccc cagaagttcc
     6841 cccggtggtg gaatcacctt ggaccggatt gtccatcagg cgcgcctcct gacggtccgg
     6901 cgcgacacat ggcgggcgtc cagcccggac agcccccgca ccgcgacgta cgccttctcg
     6961 cgcccgggca gcgagacccg gccgcgcagc acggcctccg gctcgcgctc gatgcggtcg
     7021 aggaggcgcc ggtagatgcc ggccatggcg gcgacgcagg caccgctgcg ccggtcgagc
     7081 aggggcagca gccggtaccc ctcggcgaac agggcgcggg cccggcgcac ctcgaagtgg
     7141 acgagcccga tgaagtcgga gtcgcgcggc ggcaccggcc cggcgaaccc ggcggagcag
     7201 ccgaacttgg cgaggtcgtc ggcgggcaga taggtgcgcc cgccctcggc gtcctcgcgc
     7261 aggtcccgga ggatgttggt gagctgcagc gcgagcccca aggtgtcggc gtactcggcg
     7321 gcgcgctcgg cgccgcgtgc gcccggctcg gtaccgaaca cgccgagcga gacccgcccg
     7381 atggcgcccg ccacgcaacg gcagtacagc ttgaggtcgt cccaggtctc gtaggtctcg
     7441 ccgcgcacgt ccatcaggac gccgtcgatg agctcgtcga ggccgccgag cgggatcggg
     7501 aactgcccgc tcgcgtgcgc gagggcgacc gccacggggt cggtgtcgtc ctcgtccacg
     7561 gcgccgtcgc gcacccgggt cagcagcgcg cgggtgtcct ccagccgggc cgccttcacc
     7621 tcgggcgtga gcgcgccgtc gccgatgtcg tcgacgcgcc gcgagaaggc gtacaccgcc
     7681 gacatcgcgc ggcgcttggc ggtcggcagc agcctgatgc cgtaggcgaa gttacgggcc
     7741 tgctgcccgg tgacggcctc gcagtagctg tatgcggcga gcaccggcgc ggacacgcgt
     7801 gcatccggct ccacggtccg gatcacccct cttctcgcag agtcaggccc acctcacgca
     7861 gcagccggag cttgccgggc ttgggcgggc cgggaagtac gtcgtatgcg gcggcggcga
     7921 tcgcgtcgac cgccgccctg ccccccgcca cgaaacccgc caggagcagc cgcagcctgc
     7981 cgtgcacgct acccacgagg gggattcctt catccagcag gtcacgggcg cgttgggcct
     8041 cgtacgcgac cagcgcgcgc accgacgcgc ccgccgtggg ggcggcgaga tccgcctcct
     8101 cgacgtggaa gcgcttcatg tcggcggcgg gcagatagat ccggtcgcgg cccaggtcct
     8161 cggccacgtc ctggaggtgc tcgacgatct gcagcgccgt gcagacggcg tccgaacggc
     8221 gctcgcgttc gggggtcgag gtgccggtga tgccgagcac gagccggccg acggggttgg
     8281 cggacagctc gcagtaggcg aggaggtcgt cgtacgtctc atagcgcgtg acgagctggt
     8341 cctggcggtt cgcggcgatc aggccgagga acggctcggg ggtgagggag cggcggcgca
     8401 cggtcggctg gagccggcgc agcagcggat ggcgcggagt cccgtcgaac accctgcgca
     8461 ggtcggcctc gaaggcgtcg agcaggacca gccggtcctc ggccgccgcg gacgacacac
     8521 cgaggagccg ggcgtcggcg ccgcccgggg cgaggtcgcc gtcaccgatg tcgtcgacga
     8581 gccgggcgaa gccgtagacg gccatgaggt cgtcgcgcca ggccctgggc aggaagaacg
     8641 gggccacggg gaagttctcg gcggccgcct tggcgagggt gccctgctcc cggtcgcccg
     8701 ggtacgccgt tccggctttc gtcaccgcgc gccacccggc gcggggacgg caggagcgtc
     8761 gcggaggtgg ggagtttccg tagccattgc cgtcacatct cccgttctac accgacaacg
     8821 catttaaccc tatttcagac acgccgcccg ctgccggcac ggagtgacgg atgccgggtg
     8881 tcgcgcatta tggacctact tgccgcgatt cagcaccggt acagcttacg ttgtacagcg
     8941 cgccgcgctc ccccggggtg tcccgcgcat cacaagaaca caccgatcga ccccgacttg
     9001 tcggcttcat acgggagttg gccgttcctc gaccctcctc ggggccgggc tcccgcagcg
     9061 cccccgggcc ctcgtacggc cgaccccgcc ggacgcgtgc tcggcggggt cgggacggac
     9121 gcgcgcggcg gaacgggccg ctacttgccc gtgaacttct cgtactcctt catgacctct
     9181 tcggtcggcc cgtccatccg cagctcgccg cgttccagcc acaggacgcg gtcgcaggtg
     9241 tcgcggatcg acttgttgtt gtggctgacc aggaagaccg tgccggcctg cttgcgcagc
     9301 tcgcggatcc gggcctcgga gcgcttctgg aacgcccggt caccggtggc cagcgcctcg
     9361 tcgatcatca ggacgtcgtg gtccttggcg gccgcgatgg agaaccgcag ccgcgccgcc
     9421 atgccggagg agtacgtgcg catcggcagc gtgatgaagt cgcccttctc gttgatgccc
     9481 gagaagtcga cgatctcctg gtagcgctcc ctgatctgct cccgggacat gcccatcgcg
     9541 agaccgccca atatgacgtt gcgctcgccc gtgaggtcgt tcatcagggc cgcgttcaca
     9601 ccgagcaggg agggctggcc gtcggtgtag accttgcccc tctcggcggg cagcaggccg
     9661 gcgatggcgc gcagcagggt ggacttgcca gagccgttgg agccgatcag gccgatggcc
     9721 tcgccgcggt aggcgacgaa ggagactccc ttgacggcgt gcaccttgcg cacaccgcgc
     9781 gccgtgtcgt cggaacctcg cttgaggatg cggctcaggg cggcggtggc gctgcccttg
     9841 ccggtcctgg cgccgttgac gcggtagacg atgtgcagtt cgtccgcgat gacggtcgga
     9901 acgcgtgcct cagccacggc cgtacctctc ctccgccttc cagaagtaca cgaagccgcc
     9961 gacggcgacc acggccgccc agccgccggc caccgcccac acgtgcgggg gcaggttggc
    10021 ggagccgtat ccgtcgatca gcgcgaagcg catcaggtcc atgtagatcg cggccgggtt
    10081 ccactggagg acgtcggaga tccaccccgg gtggtcggcc agcatgaccg ggatcgagaa
    10141 catcacgccg gacgcgtaca tccacgtgcg catcacgaac ggcatcagct gcgcgaggtc
    10201 gggggtcttg gaccccaggc gggcgaagat catcgccagg ccggtgttga agcagaactg
    10261 cagcaccagc accggcacga tcagcagcca cgacagtctc ggatagctgc cgaacccgat
    10321 cgcgacggcg aacagcacga tcatcgagaa cagcagctgc tggagctgct gcagcgagaa
    10381 cgagatgggc agcgaggcac gcgggaagtg cagcgcgcgc accaggccga ggttgccgga
    10441 gatcgcgcgg acgcccgcca tcaccgagct ctgcgtgaag gtaaagacga agacgcccgt
    10501 gaccaggaag gggatgtaga tctcgcggcc cattccccgg tccgcgttca ggatcaggcc
    10561 gaagatgagg aagtacacca gcgcgttcag cagcggggtc gccacctgcc acagctgccc
    10621 gagcttggcc ttgctgtact gggcggtgag cttggcctgg gagaaggcga ggatgaagtg
    10681 gcgccgtccc cacagctggc ggacgtactc gacgagtccg ggccgggcac cgctgaccga
    10741 gagcccgtac ttggcggcca gctcggccgc ggtcatcccg tcgtcgggcg acggtcggtc
    10801 gctcaccgcg acgccgccgt catgcgttgt ctcactcacg agtggaaact ttcgtcctca
    10861 atgtgcgcag cctggtcgga ccgaggcgga aaacctggga ccgggtacgg ccgaatgctc
    10921 tcagataccg agcttgtcag atgacgggag gtcggcccag tcgtgtcagc cgccacaccg
    10981 tacgccaccg catgggcctg cgggggccgc acgggctcgt ccagccctcc ttgaaaccgc
    11041 cgagccatgc cttcagggcg ggcccggacg gcttgcggag cagggtgagg agcagccaga
    11101 cgcccaggta cacggggacc aggagcacgg ggaggttgcg gcgcgcgagc cagacgcggt
    11161 tgcgcgcgac catgcggtgg tagaccgcgt gccgcgaggg cgcggtggtc gggtggtaca
    11221 gcaccatgtc ggcccggtag tcgatcatcc agcccgcgtc gagagcccgc catgccaggt
    11281 cggtttcctc gtgggcgtag aagaattcgt ccgggagtcc gccgacttcc gcgaggacct
    11341 tcgtacggac cgcgttcgcg ccaccgagga aggtggtcac gcgcgaggag cgcatcgggt
    11401 cggaggcccg cagccggggg acgtgacggc gctgggtcac accggtctcc gggtccgcga
    11461 tgcggaagct gatgattccg agctccgggt cggccgcgaa cgcctcgcgg cacagctcgg
    11521 ccgtgtcgtt gcgggcgagc aggccgtcgt cgtcgaggaa gagaaggatg tcgacgtccg
    11581 agccgccggg gccgaacgcc tctatgccga cgttgcggcc gccggggatg ccgaggttct
    11641 cgggcagctc cacggtgcgg acgccttcgg gcacctcggg caccggggag ccgttgccga
    11701 cgacgaccac ctggacccgg tcgccctcct gcttggcgac cgagtccagg agggcgcgca
    11761 gctcctcggg gcggttgccc atggtgatga tgaccgcgcc gaccttcagc ggcttccttg
    11821 cggtactcac ttcagcctgc tcgacgcgag gatggacacg aggtgcagca ccgtctggag
    11881 cagcgcgatg ccggccagta cggcgacccc gagccgcgag aagaacaggt cgccccgcgc
    11941 cgtgtccacg atcgcgagga ccaggatcag cagggacgcc tcgatcccga ggacgagacg
    12001 gtggaactgc agcgccgagg ccgcccggcg ggccagcgcc agtccggacg agcgcggcgc
    12061 tgacgccgac tcctgcaccg gcggcttccc ggtctggtgc cgggcgacgc cgacgagatc
    12121 ggtctccgcc ttgatcagta cggcgccgag ggcggcgagc gtaccgagga aggcccacag
    12181 ccagtcgatc cgtccggtgc cccacagatc ggcggcgcgc aggccgaagc cgaccagcac
    12241 ggcggcgtcg cacaggtacg cgccgacccg gtccaggtac accccggcca gcgagtactg
    12301 cttcttccag cgggcgatct cgccgtcgac gcagtcgagg agcaggtaca gctgtaccgc
    12361 caccacgccg aggacggcgc cccagattcc cggcaccagc agggccgggg cggcgagcac
    12421 gccgaagagg gtcatgagat aggtcagctg gttgggcgtg accctcgtgt tcaccaggtg
    12481 ccggtcgatg cgcagcgaga tctcgcgcat gtagagccgg ccggcccagt gttcgccgct
    12541 ccgccggtcc ttcacccccg cggggtggac gaccgggcgg agttcagcta ccgatggctt
    12601 ttgcatagtc ggcgtaggcg tccctgatct ggtcggtgtt caggtcgaga tgttcgagga
    12661 tggtgtagcg gccgggccgg gtctgcggcg cgaattcgac aacctggacg aactcgtcca
    12721 cggtgaagcc gatctcctcc ggcagtacgg gcagcccgtg gcggtgcagc acctcggcca
    12781 tgtaggccga ctcctcgtgc gccccgcgca ggtacatcgc gaaggccgcg cccaggccgc
    12841 actgctcgcc gtggctagcg gcgcgccggg ggaagagcag gtcgaaggcg tggttgatct
    12901 cgtggcaggc gccggaggcg gggcgggagt cgcccgcgac cgacatcgag ataccggtga
    12961 ggaccaggcc ctcggcgagc acctggagga agccgtcgtc gccgacgccg ccggggtggc
    13021 gcagcacggc ctcgccggcc tgccgggcca tggcggccgc gagaccgtcg atgtcctcgc
    13081 ccttctcgcg ggcggcgagc tcccagtccg cgaccgcgga gatgttggac agggcgtcgc
    13141 cgatgccgga gcgcacgaaa cggaccgggg cctcgcggat gacgtcgagg tcgatgacga
    13201 ccgcgatggg gttgggcacg ccgtaggagc cgcggcccgc gtcgttgtcg agggtcgcga
    13261 cgggcgagca cagaccgtcg tgcgagaggt tcgtggcgac cgcgaccagg ggcagcccga
    13321 cgcgggcggc ggcgaacttc gcgcagtcga tgatcttgcc gccgcccagg cccacgacgg
    13381 cgtcgtagcg cccgcgcttc atcgcgtcgg ccagctggac cgcgtcgtcc agcgtgccgc
    13441 cgccgacctc gaaccagtcg gcgtccggca gcgccgggca gatccgttcc cggagcttcg
    13501 ccccggagcc gccgctgatg gcgacggcca gcttgccgga cgacgagatc cgctggtccg
    13561 cgaggaccgt cgccagatcg tcgagggcac ccgggcggat gtccacgacg atcggcgagg
    13621 ggatgagcct cgtcagtact ggcacgcgat ctcccggccc ttggcgaggt cgtcgtggtt
    13681 gtcgatctcg acccacttga cgtcgccgat gggcgcgacg tcgatcttga agccgcggtt
    13741 gacgagctcc tggtatccgt gctcgtagaa ctgctggggg tccgtctcga agacggtctt
    13801 cagggcgtcg gccagctcgt cggcggcctc gccctcgatg agggtgacgc cgatgtactc
    13861 gccggacgcc tccgccgggt ccatcagctt cgtgatcttc gtcatgccct tctcggcgtc
    13921 gacgacgacc ttcatctcct cgtcggcgag ggacttcacc gtgtcgatcg cgagaatgat
    13981 cctcttgccg tcgccgcggg cggcgagcag cgtcttctcg acggagaccg ggtgcacggt
    14041 gtcgccgttg gcgaggatca ccgagtgctt gacggcgtca cggccgcacc acagggagta
    14101 ggcgttgttc cactcctccg ccttgtcgtt gtcgatcagg gtgatcttga cgccgtactt
    14161 ctgctccagg gcctcgcggc gctcgtacac ggcctccttg cggtagccca cgatgatcgc
    14221 gacctcggtc aggccgatct cggcgaagtt gccgagcgtc aggtccagga cggtgaggct
    14281 ctcctcgtca ccctcgggtc cgaccggcac cagcgccttg ggcagggtgt cggtgtaggg
    14341 gcgcagacgc cgtccggcgc cggccgccag cacgaggccg atcatgcggg ttctccttca
    14401 tcgtgtacgg cgggtgcgcc gcgcctgtgg gcggtcaccc agaagcggat gctctcgaag
    14461 agcaccacca gtgccacggc cacggccaga accgtgagcg cgaccttgaa acctgtggcc
    14521 gtcagcagcg cggccagaac ggtgaccagc agcgtcctgc cttcgtgtcc gccgatcgcc
    14581 cgcaccagcc agtgcggcgg cgcgccggcg tcgccgcgga tgcggtacac cgtgtcgtag
    14641 tgatggtagg cgacggccgc caccagcccg aaagctgccg gaagcactcc gttcacgtcg
    14701 gctttcgccg ccaggatcag gacggtgagg tactcggcgg cgcggaggag gggcggaacc
    14761 agccagtcca gggcgccctt cagggggtgc tggatgacgt ccgcggacac caggacgtac
    14821 acgccggcgc acaccacgac cgaccagccg ggcccgtcga accaggccgc gagcaccacc
    14881 acggcggcac cggcgacggt cagaagccgc gccggaacac gcggcccgct gggcagcagg
    14941 cgtgcgagca cctcggccag gggcccgctg tcggccaggt ccgccagcgc gcgggccgcc
    15001 cgctccgtcc gctgtgctct acgcgtcagg gaccgaagca cccggcccgc cgtggtgtac
    15061 agcccggcga gcccgcagcc gatcagcagg gcgtagaagg tgatgcgcgg cgtggtcagc
    15121 gcggtgagga cggcgatcat cgcccagcgc tcaccgatcg gcagcacgat catgcggcgc
    15181 agccagaccg tccagccgac gcggtcgagc ttgccggaga gggcggcggc gggactggcg
    15241 tcggctgcgg cggcagggtc cctggtgttc gcctcgttga acgagaaatc cacgacatgg
    15301 cggcaggcct gcaggatcat cgcgcccagt gcgagcgccc acacgtcgtc cccgccgcgg
    15361 gccgcgccga gcgcgagacc cgcgtagtag gcgtactcct tggcccggtc gaaggtggcg
    15421 tcgagccagg cgccgagcgt cgagtactgc agggagtagc gggcgagctg accgtccgtg
    15481 cagtccagca cgaaggaggc gatgaggagc gcaccggccg ccacgaagcc gccgcgggtg
    15541 ccggtggccg cgcaccccgc cgcgatcagg gcggtgagca gcgacgcggt ggtgacctgg
    15601 ttgggggtga ggccgcggcg cgcacaccag cgggcgatgt agcgcgagta cgggctgacg
    15661 aagtacgtgg tgaagaagcc gtcgcgggac ttcaccgccg tacgcagccg tacggcctcg
    15721 tcgtcgaccg cggccacggc ctggcgggcc tcgttgcggg cctgcgggtc ggccgggacg
    15781 gtggcgacca ggctgccgag ctcgggccgg tgcacgggca ccccgtcggc ggcgagggcc
    15841 gcggcgacgc cgtccacggc gacggccgac ccgccggacc cgccgtcgcc ggacgcgcgg
    15901 gagcccgtcc gggccagggc ccgggtcagg gcctggcggg cggcgggctg gacggtcacg
    15961 gcgccgggca gcgctgcgac cggaaagcgg gggtcggtga gcccgaggcg cagcgcgtgg
    16021 aggtggccca cgaaccgggc gtccacgagc gcgacccgct ggtctccggg gatccgggcg
    16081 agcagcgtct cggcgtcacc ggcgtcggag gcgacccgca cgtcgaaacc gagtgcccgc
    16141 agctcgccct ccagcgacgc tccgggtacc ggctgaccgg tgaggatggc ggtcgacaga
    16201 cgaactcact ccctgtgtgc cggcggctgc gccggccgtg cgcgtggtgg ggggcgccgg
    16261 gtggcccgcg gggccgggcg gcgtgtcggc agaggctatc ggatgatgag aagcgagcgt
    16321 tcaccgcctg ttcaggatcc gctcaacctg ctctgctcca cctcggccac gatcatcatc
    16381 ggggattccg gggccgtgcc acaaacccgc cctcgcagac cagcgcattc acggcagcac
    16441 ggcgcggctc gttcacgacg tgcgtgcggc gcgttcacga tgtgcgtacg gcgcgttcac
    16501 aaccccgcgt acggtgcacg cccggcctcg cgcacggcgc acgcacggcg gcgcgcacga
    16561 cgggtccacg aggcgcgcgg tcgccgcccc tcgcacgggg gaggggcgtt cccgttcgtg
    16621 aaccggtcga gctgatcggt ggggcgaccg gcggtcgccg cccgtcgggc cgcgccgcgc
    16681 cccggggacg cgccgcgcgg cggtcgcgac cgggcccgcc gcccgggagc cgggatggac
    16741 ggcccggcgc ggggtacgcg agatggccgg gccggtccgg gctaagcggc ggccgcaccc
    16801 gggaaatgat cgccgcggcg tctgagcagg ctctgacctg cggcttgtcc tcgcttacct
    16861 ccacgcgacg ttttcgcagg tcagagcaga tgacaacggt gttcaccacc acgttgccgg
    16921 atacccccca cccgtagttc actgggtgct ccggaggacg gagacggaaa gggcggagtc
    16981 catgggggcc ggtcacgatc acgggcacgc gcacggcgcg ccggccgggg gcacggcgac
    17041 ggccgcgtac cgcggcagac tgcgggtggc actgtcgatc acgctcaccg tcatggtggt
    17101 cgagatcgtc ggtggcatcg tcgcggattc gctcgcgctc atcgcggacg cggcgcacat
    17161 ggcgacggac gccctgggcc tgggcatggc gctgctggcg gtccacttcg cgggccgtcc
    17221 ggcgaacgag cggcgtacct tcggctacgc gcgcgccgag atcctcgccg cgctcgccaa
    17281 ctgtctgctg ctcctcggtg tcggcggcta tgtgctgtac gaggcgatcc agcgcttcct
    17341 caccccggcc gcgacggagg gcggcctcac gatcgtgttc gcgctgatcg gcctggtggc
    17401 gaacatgatc tccctcacgc tgctggcgcg tggccagcag gagagcctga acgtgcgggg
    17461 ggccttcctg gaggtggcgg cggacgcgct gggctccgtg gccgtgctgg tctcggcggt
    17521 ggtcgtgctg acgacgggct ggcaggccgc cgacccgatc gcctcgctgg tcatcggcct
    17581 gatgatcgtg ccgcgtacgg tgaagctgct gcgcgagacc ctcgacgtcc tgctggagtc
    17641 ggctcccaag ggcgtcgaca tggccgagct gcgtgcgcac atactcgcgc tgcccggggt
    17701 ggaggacgtg cacgacctgc acgcctggac catcacgtcc gggatgccgg tactgtccgc
    17761 acacgtggtc gtcggcagcg acaccctgag cgcgatcggc cacgagaaga tgctgcacga
    17821 gctccagggc tgcctcggcg accacttcga cgtcgagcac tgcacgttcc agctggaacc
    17881 gagcggccac gcggagcatg aggcgaagct gtgccactga gcccggccgc accgcggcca
    17941 cgaacccgaa ggtgcacgtc ttgaccgaca ccccgtccga gccgatcccc tcctggcgca
    18001 cgcgcccgga ggccgccggc gaccgcgccg aggtgcatgc gctgaccgtc gccgccttcg
    18061 ggcgggccga ggaggccgat ctggtggacg cgctgcgtgg ggacgccggc gcctggctgg
    18121 atctggcgtc cgtggccgag gcgccggacg gatccgtcgt ggcgtacgcg ctgctcaccc
    18181 gctgccatgt cgacgaggcg cccgcactgg cgctcgcccc tgtcgcggtg cggcccgacc
    18241 ggcagcgcga gggcgccgga gccgccgtcg tacgggcggt gctcgcggag gcacgcgcgc
    18301 gcggggagcg gctcgtgctg gtgctcgggc accccgagta ctacccgcgc ttcggcttcg
    18361 cgcccgcctc ggcgtacggg atccggcccg ggttcgaggt tccggacgag gcgatgatgg
    18421 cgctcgtgct ggacggctcc ccgtccgtgg cgccgggcac gatcgtttac ccggccgcct
    18481 tcggcgtgtg atccccgtcg gccgcgtttc ccgcccggcg tggcctggcc tggaacggcg
    18541 cgccgtgaag tgtcgggagt gccggattcg tacggcagac ttgaggctcg acgaacgagg
    18601 cgaaggacgg ttatgccgat cacacctgcc accgcgatgc acagttcacc atgggggcac
    18661 ctcccaggcc ctcaaggctc tgggggaggc accaccgaag cgatcctgct ggaactggtc
    18721 gacga
//
