LOCUS       NZ_BMVW01000008        10591 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces poonensis strain JCM 4815 sequence08, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVW01000008
VERSION     NZ_BMVW01000008.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces poonensis
  ORGANISM  Streptomyces poonensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 338141)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 137X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650915.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:27:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,577
            CDSs (total)                      :: 7,501
            Genes (coding)                    :: 7,228
            CDSs (with protein)               :: 7,228
            Genes (RNA)                       :: 76
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 273
            CDSs (without protein)            :: 273
            Pseudo Genes (ambiguous residues) :: 0 of 273
            Pseudo Genes (frameshifted)       :: 96 of 273
            Pseudo Genes (incomplete)         :: 224 of 273
            Pseudo Genes (internal stop)      :: 19 of 273
            Pseudo Genes (multiple problems)  :: 60 of 273
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:46:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 75201
            Orig. end                         :: 85792
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVW01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10591
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="melanin"
                     /region_number="1"
                     /rules="melC"
                     /tool="antismash"
     cand_cluster    1..10591
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="melC"
                     /kind="single"
                     /product="melanin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10591
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5591](+)"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5591
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="1"
     misc_feature    complement(2064..2077)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.92"
                     /tool="antismash"
     gene            2097..2336
                     /locus_tag="IE242_RS20665"
                     /old_locus_tag="GCM10010365_42360"
     CDS             2097..2336
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019056482.1"
                     /locus_tag="IE242_RS20665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_42360"
                     /product="chaplin"
                     /protein_id="WP_189861421.1"
                     /transl_table=11
                     /translation="MSRIAKGLALTSVAAAAVAGTAGAAVADSGAQGAASNSPGVISGN
                     TAQIPIHLPVNLCGNSIDIIGLLNPAFGNQCVND"
     gene            2596..3462
                     /locus_tag="IE242_RS37830"
                     /old_locus_tag="GCM10010365_42370"
     CDS             2596..3462
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE242_RS37830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010365_42370"
                     /product="hypothetical protein"
                     /protein_id="WP_229859243.1"
                     /transl_table=11
                     /translation="MSLPPVRHLASSAFCATVLLGIAAPGASAAGSDPARDRVQTAAPA
                     PDAETLLARTRALSGLDDALEPLTDLLESALEADDDERFSDGQVAAYRDAVQQVVTKLN
                     SLALVAPTLPQSPVEPQSPAVPQSPVAPESPVAPQSPAAPTSPASPVSPALPQWPTAPA
                     SPSLPAEPPYPAEPPYPAEPSSPAAPHTPADASRVDDPAAAKSDAITALEAAVDALLAA
                     GSSGESADVEPAADSVLTGLANVVAAALLGNGVPAADAAGRPEQAPPADTASILPQKSP
                     TAPLLPF"
     gene            3706..3996
                     /locus_tag="IE242_RS20675"
                     /old_locus_tag="GCM10010365_42380"
     CDS             3706..3996
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014672804.1"
                     /locus_tag="IE242_RS20675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_42380"
                     /product="hypothetical protein"
                     /protein_id="WP_189861422.1"
                     /transl_table=11
                     /translation="MKSLKAAAVVTGSVVLAGAATPASAFDPSEVAPMSLNGAWNQLMS
                     EPIDISPLKQQSNMLDTENKDSLLSSVKSATTALNAAGSPLRLLGGLPLGR"
     gene            4373..4867
                     /locus_tag="IE242_RS20680"
                     /old_locus_tag="GCM10010365_42390"
     CDS             4373..4867
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013003505.1"
                     /locus_tag="IE242_RS20680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_42390"
                     /product="DUF5949 family protein"
                     /protein_id="WP_189861424.1"
                     /transl_table=11
                     /translation="MTSTPTEARPFRPGDLGTLVVMAWSGGTADGDMPYLLAYPLGDGE
                     NGPEASSAAVGQLLRDIGLPLGEETDAAGLPHLPVTLVLEAGQAVVAMPHFAARCPAPD
                     EWLAAVTERGYAHLVFATRPWPEAAPGRSVEPEALAAFAGAPETLSSAAHVLLPARSPR
                     S"
     gene            5001..5591
                     /locus_tag="IE242_RS20685"
                     /old_locus_tag="GCM10010365_42400"
     CDS             5001..5591
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     melanin: melC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020132940.1"
                     /locus_tag="IE242_RS20685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_42400"
                     /product="tyrosinase cofactor"
                     /protein_id="WP_229859194.1"
                     /sec_met_domain="melC (E-value: 5.6e-44, bitscore: 143.9,
                     seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLFVRRASVLFVSGVRRRNVMRGLFAVATALALAPVVTASRNRHS
                     RHPAHPGSTVLPPGHTAPSGGIALDEVDVAFDETYCGCRIRGGIAAEERATAMGARWQV
                     TVDGRPLHLMRRADGTYLSMVDHYRSYPTALEATRAAVDELGPAQRLRVTDAVPGGRHR
                     KNGHRESHERENGHRENHQREKRHRENSHGVRA"
     gene            5575..6441
                     /locus_tag="IE242_RS20690"
                     /old_locus_tag="GCM10010365_42410"
     CDS             5575..6441
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019325459.1"
                     /locus_tag="IE242_RS20690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_42410"
                     /product="tyrosinase family protein"
                     /protein_id="WP_189861426.1"
                     /transl_table=11
                     /translation="MAYVRKDVSTLTRAERRRFVGALLELKRRGEYDEFVRTHIDYYVP
                     DGERGLRTAHMAPSFLPWHRAYLLEFERALRRVEPSVTIPYWDWTRDRSTTSAPWTGDL
                     LGGNGRRTDHRVMTGPFAYATGDWTVTVGVTDVAYLTRDFGHTRQPVDLPTRREVDEAL
                     ADPVYDSAPWDSTSRKGFRNKLEGWGAGRGSASWRIHNRVHRWVGGHMVGAASVNDPVF
                     WLHHAFVDLQWTRWRRRHPEARYLPARPLDVDDPQRGRVVARHEPLPPWEATPDRMEEV
                     GEIYRYA"
     gene            complement(6636..7031)
                     /locus_tag="IE242_RS20695"
                     /old_locus_tag="GCM10010365_42420"
     CDS             complement(6636..7031)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018106099.1"
                     /locus_tag="IE242_RS20695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_42420"
                     /product="chaplin"
                     /protein_id="WP_189861428.1"
                     /transl_table=11
                     /translation="MSRMAKAAAVALGTSAVMLSGAGLATADSGTQGSALNSPGIISGN
                     AAQLPLDVPINLCGNSINIIGLLNPAFGNVCADVGRKHHHGHQNGHNNGHNNGHNNGPQ
                     NGSHNGSHHGSQNGSHNGSHGSGGYGR"
     tRNA            complement(7370..7445)
                     /anticodon=(pos:complement(82611..82613),aa:Arg,seq:tct)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="IE242_RS20700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GCM10010365_t00480"
                     /product="tRNA-Arg"
     gene            complement(7370..7445)
                     /locus_tag="IE242_RS20700"
                     /old_locus_tag="GCM10010365_t00480"
     misc_feature    complement(7712..7725)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     gene            7756..9363
                     /locus_tag="IE242_RS20705"
                     /old_locus_tag="GCM10010365_42430"
     CDS             7756..9363
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016435092.1"
                     /locus_tag="IE242_RS20705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_42430"
                     /product="dynamin family protein"
                     /protein_id="WP_189861430.1"
                     /transl_table=11
                     /translation="MVTLDVRPQLLDALSALRDRVAAVRYPLPLAGAPRARANRDELLA
                     QLDDYLVPRLREPEAPLLAVVGGSTGAGKSTLVNSLVGRRVSEAGVLRPTTRTPVLVCH
                     PGDHHWFSGMRVLPHLTRAWVPRREPGGEPFPDGGDGRRVLRIETADSLPPGLALLDAP
                     DVDSLITENRVLAAELISAADIWVMVTTAARYADAVPWHLLRTAKQHRATLITVLDRVP
                     HQVVSEVSRQYGALLAKAGLGEVPRFTVPELPESAWGGGLLPATAVAPLRSWLTHQATD
                     PGARHQAMARTAHGVLDSLRARMPELAGAAAAQYAAALRLTAAVDTAYDREHTRVKRSL
                     QSGAVLAGDALKRWRGYPLDCTAGELLDALVESLAALLLCAVIAADQCVDDAWRREPAA
                     GAPELTRRDPVLESAEHRIGMAVRRWRRVLEEYAEEEARDLGGSTTPDPEALAALVATA
                     LLGGRRVRSAGERLAELIGAHGALRLRDRGGRLLTEYLGRALRVERERRLAPLEALDVT
                     PEPQVELIAALSVLQKER"
     misc_feature    complement(9368..9383)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
ORIGIN
        1 cgccgccggg cagttcgcgg tgggcctctg cggtgcccag cagctcgcgg tacacgcccg
       61 tgacggcctc ggccgtgtgc cgtacgtcgt gcgcggtcag cacgtggcgg cgcgcctggc
      121 ggccgagcag ggcgcgcagc gacggatcga ggaggagccg gacgatcgca cgggccagtg
      181 cggccgggtc gccgacaggc accggtttcc ggcccggcgg caggctctcg cgggcgccgt
      241 ccacatccgt gagcacgacg ggccgtccgc acgccatggc ctccagcggt gccagcgcca
      301 tgccctccca gcgggacggc aggacgacga gatcggcggc ccggtaccag ggcacggcgt
      361 cggcggccgc ccccgcgaac agcacgcccc caccggcgcc ggcgagcttg cgcagtcgcg
      421 cggcgtccgg cccgtcaccg acgagcacga gacgcgcctc cggcacccgc agcaccaccg
      481 aactccacgc cgccagcagc acatcctgcc ccttctgccg gcacagccgc ccgacgcaca
      541 ccacgagcgg agcccgcgct ggcaccccgt cgagcagcgg aatccgggcc cgtacgctct
      601 ctgcggcttc tgtagcctcc acgaccctcg cgacctctgc gatctctgcg atctccgagg
      661 tctctgcggt ctccgcggtt tctgcggtct ctgcggcctt cgtggtcacc gcggctcgta
      721 gggccttcgc cgccgccatg gggcggaagc gctccgtatc gactccgttc ggaatcaccc
      781 gccagtgcgc ccgaagcccg gcccgcaccc cggtcagccg ctcggcctcg ctcacgcaca
      841 cgacccggtc ggcccaccgc accgcccatc gctcccacgt ccgggcgagc gctgcggtga
      901 ccccgccggc cgcctcgaag gaccaggcgt gcggctggaa cacggtcggg atccgcccgc
      961 gtacggcgat ccgcccggcc agcccggcct tggcgctgtg cgcgtgcacc agatcgggcc
     1021 gtaccgcgtc gacgatccgg gcgatccggc gcacctcccc gagcagcgac ggcccgggcg
     1081 aacgcgtcgc atcccaatgc cgtacgtcgg ccccgagcgc ccggagcgcc ccgagcgcct
     1141 gaagctcccc gagcgcccgg agcgcgcggg cgggagtgcc gtagccgccg gggcaggcta
     1201 ccgagacacg cagaccgtcg gcgagctggg cccgtaccag gtccgtgacc acctgggcca
     1261 ctccgccgcc gaccggctgg gcgatgtgca gcacccgcag cgggggcagg gagggcaagg
     1321 gggaccacga gggcaacgag gagtcgggcg gtgacgggca catgcgggtt ccttgctcgc
     1381 ggacggcgct gggggcgcgc gtcactgctg ggcgttgacg acgacgaagc gcgcccctgc
     1441 ccgggcggcg ccgcgctgcg aaacgagcga ggagaccaac tggtcaccac ggggacggag
     1501 cccattgccc ggaccggcgg cagcgaggcc acgtccgagc gcgggagcac gcaccggcgt
     1561 gcacacgtga tgagcgccgg tggccacgcg gcacaggggc cgtcaggggc atccctggaa
     1621 cccggtgggc ggacgcggag agggcacggc ggaggtccag cgccgcacgg cgcggcggac
     1681 ggcgcggagg acggcgcgac ggacggtccg gggagtgacg catgaccggc agtgctcttt
     1741 cggttgtcgc gtaggtgacg cgcgggaccg cctcggggac gccgcgtcac cccggatgcc
     1801 gggtgccggg tgccgggtgc cgggtgccgg gaggcgagcg gcggggtgtc gggaggcgag
     1861 cggcggacgg cgtgcggcgg acggcggacg gcgacccggg agggaccaca accgtatccc
     1921 gctgtccccc tatccgcgct tatcggtgaa acaggaaaaa tgtgtcgcca tgggcaagat
     1981 gggcgtttgc gtggatcact ccttcggacg cgcaaccccg cgcgcgtccg ggcgttgatg
     2041 ccagcgtcgg gcgcactgcc cggatgttct gcgtcaacac caaggagcac ttctccatgt
     2101 cgcgtatcgc gaagggcctg gccctgacct ccgttgccgc cgccgccgtg gcgggcaccg
     2161 ccggcgccgc cgtcgccgac agtggcgcgc agggggccgc ctccaactcc ccgggtgtca
     2221 tctcgggcaa cactgcccag attccgatcc accttccggt caacctctgc gggaactcca
     2281 tcgacatcat cggtctgctg aaccctgcgt tcggcaatca gtgcgtcaac gactgacatc
     2341 acgacgtacc gcccgacggc cggccgtcct ccctgtacgg ggaggacggc cggaccgcgt
     2401 tgtgcggtga ccggtcgggg atgccccgaa tgggggctgg cgggcggcag gctcgtgcat
     2461 ggggcctcac cagcgaggac gtggacgaca cgagcgacgg gccgccgcgc ggcacgggcg
     2521 atcggttgca ggcggcgatg accgatttca cggtgatcac acgatctgtc gcaccgaccg
     2581 aagggaacag cccccatgag tctcccgccc gtccgacatc tcgcgtcgtc cgcgttctgc
     2641 gccacggtcc tgctagggat cgccgccccc ggcgcgtctg cggccggcag cgacccggcg
     2701 cgcgaccgcg tccagacggc ggcaccggcc cccgacgcgg aaacgctcct ggcgcggacg
     2761 agagcgctga gcgggctcga cgatgcgctc gagccgctga ccgacctgct cgagtcggca
     2821 ctcgaagccg acgacgacga gaggttctcc gacggccaag tggcggcgta ccgggatgcc
     2881 gtccagcagg tggtcaccaa gttgaactcg ctggctctcg tcgcgccgac gctcccgcag
     2941 agtcccgtgg agccgcagag tcccgcggtg ccccagagtc ccgtggcgcc ggaaagccct
     3001 gtagcgccgc agagccccgc ggcgccgacg agtccggcga gtcctgtctc ccccgcgctg
     3061 ccgcaatggc ccaccgcgcc cgcgagcccg tcactccccg ccgagccgcc gtaccccgcc
     3121 gagccgccgt accccgcgga gccctcgtct cccgccgcgc cccacacccc tgcggacgcg
     3181 tcgcgggtcg acgaccctgc cgcggccaag agtgatgcga tcaccgctct cgaggcggcg
     3241 gtcgacgccc tgctggccgc cggctcctcc ggtgagtccg ccgacgtgga gcccgccgcc
     3301 gacagcgtgc tgaccggcct ggccaacgtg gtcgcggccg ccctgctcgg caatggagtg
     3361 ccggctgcgg acgcggccgg cagacccgag caggcaccac cggcggacac ggcctcgatc
     3421 ctgccgcaga aatcgcccac cgctccgctg ctccccttct gagcccccgc cgggagcaac
     3481 ggctcatcac ctcctcgtat aagccgtttc acagggaaat cagtcgtgcc ggcctctgtc
     3541 cggccagtac gacggtctcc ttgcgaggag accaggaatt tccggaacac ggggtttccg
     3601 gggcgtccgg gactcgttgg gcagggcgca gtgagagccc gggtctttcc ctgcccgggc
     3661 ggtgagaatt ccccggcggt gcaagtcgcc gaagaaagga acaccatgaa gtcgctgaag
     3721 gccgccgctg tcgttaccgg gtccgtcgtc ctggctggtg ccgccacacc ggcctctgcg
     3781 ttcgacccct cggaggtggc gcccatgagt ctgaacggcg cctggaacca gctcatgagc
     3841 gagcccatcg acatctcccc gctgaagcag cagtcgaaca tgctcgacac cgagaacaag
     3901 gactcgctgc tcagcagcgt gaagagcgcc accacggccc tcaatgcggc cggcagtccg
     3961 ctacggctcc tgggcggtct gcctctcggg cggtgagcgc ttcccggtcc tgcaccggcc
     4021 ccgcgctgga accaagtccg catcggcatt ccatatcggt gtccgcatcc ggtccgcatc
     4081 cggtttgcat ccggtccgca tccggtccgc atccggtccg catccggtcc gcatccggtc
     4141 cgcatccgat attcgcactc ggtatccgcg atcggaatgc atatcggcat tacatatgga
     4201 gtgcagcagg ccgttcgtac tgtgcgatgc ggattgtccg ccgtatgccg ttcgacgaca
     4261 ctccggcgtg cggatgacgc gcatccctcg ttcgtgtggt cgatcgaggc gtatcgccca
     4321 gtcgggtgag aaaggtgcat gaccgggccg ggagcgcggt tagggtgccg cggtgacctc
     4381 aactcccact gaagcacgcc ctttccgtcc cggtgacctg ggcacgctcg tcgtcatggc
     4441 ctggagcggc ggaactgccg acggtgacat gccctatctc ctcgcctatc ccctggggga
     4501 cggcgagaac ggcccggagg cctcctcggc cgccgtagga cagctgttgc gcgatatcgg
     4561 ccttcccctc ggagaggaga ccgacgccgc aggcctgccc cacctgccgg tgaccctcgt
     4621 cctcgaggcc gggcaggccg tcgtggccat gccgcatttc gccgcccggt gccccgcgcc
     4681 ggacgagtgg ctcgccgccg tcaccgaacg cgggtacgcc catctcgtct tcgccacccg
     4741 cccctggccc gaggcggccc ccggcaggtc cgtcgagccc gaggcgctgg ccgcgttcgc
     4801 gggcgccccg gagacgctgt ccagcgccgc ccacgtcctc ttgccggccc gtagcccccg
     4861 cagctgacgg tggccacggc ggagcgacac gccgacccgg tacgggccgc ggagccgacg
     4921 cggcccgtag ggcctccacg ggccctacgg ccagtacggc ccgtacgccg gtcgtcagcg
     4981 tgctcgtaag gagagcgagc gtgttgttcg tcagaagagc gagcgtgttg ttcgtcagcg
     5041 gagtgcggcg ccggaacgtg atgcggggac tgttcgcggt ggcgaccgcc ctggcactcg
     5101 ccccggtcgt caccgcgtca cggaaccggc actcccgaca cccggcccat ccgggcagca
     5161 cggtgctgcc cccgggccac accgcgccct ccggcggcat cgctctcgac gaggtggacg
     5221 tggcgttcga cgagacgtac tgcggctgcc ggatccgggg cgggatcgcc gccgaggagc
     5281 gcgcgacggc catgggtgcg cggtggcagg tcaccgtgga cggacgcccg ctgcatctga
     5341 tgcggcgcgc ggacggcacg tacctgagca tggtggacca ttaccggtcg tatcccaccg
     5401 ccctggaggc gacgcgcgcc gccgtcgacg aactggggcc cgcgcagcgt ctgcgggtca
     5461 cggacgccgt gccgggcgga cgccaccgga agaacggcca cagggagagc cacgagagag
     5521 agaacggcca cagggagaac caccagaggg agaagaggca cagggagaac agccatggcg
     5581 tacgtgcgta aggacgtcag cacgctgacg cgcgcggagc ggcgccggtt cgtcggcgcg
     5641 ctgctggagc tcaaacggcg gggcgagtac gacgagttcg tacggacgca catcgactac
     5701 tacgtgcccg acggcgagag gggactgcgc accgcccaca tggcgccctc cttcctgccc
     5761 tggcaccgcg cgtacctgct ggagttcgag cgggcgctgc gccgcgtgga gccctcggtg
     5821 acgattccgt actgggactg gacccgcgat cgttcgacga cgtccgcgcc ctggaccggg
     5881 gatctgctcg gcggcaacgg gcggcgtacg gaccaccggg tgatgaccgg gccgttcgcc
     5941 tacgccaccg gggactggac ggtcacagtg ggggtcaccg atgtcgcgta cctcacccgg
     6001 gacttcggtc atacccgaca accggtggac ctgcccacgc gccgcgaagt cgacgaggcg
     6061 ctggctgatc ccgtctacga ctccgcgccc tgggactcga cctcccggaa gggcttccgc
     6121 aacaagctgg agggctgggg ggccgggcgg ggcagcgcct cctggcgcat ccacaaccgg
     6181 gtgcaccgct gggtcggtgg ccacatggtc ggcgccgcct ccgtcaacga tcccgtcttc
     6241 tggctgcacc acgccttcgt ggacctccag tggacgcgct ggcggcggcg gcacccggag
     6301 gcccggtacc tgccggcccg gccgctcgat gtggacgacc cgcagcgggg ccgggtcgtc
     6361 gcgcggcacg agcccctgcc gccgtgggag gcgactccgg accggatgga ggaggtcggg
     6421 gagatctacc ggtacgcgtg aacgggcgcg ggtgcgggtg caaacgcgga agcaggggcg
     6481 ggtgcaaacg cggaagcaag ggcgggtgca ggcgcgggcg agacgcggtt gtcagcacgg
     6541 atacgaggac ggtgcgtacc gcacggaaga gccccggtgg tctcccgcca ccggggctct
     6601 cctccgccga ccgcgtccgt cggcgtcttc gcatgtcagc gaccgtagcc accggagccg
     6661 tgggacccgt tgtgggaccc gttctgggac ccgtggtgcg acccgttgtg cgatccgttc
     6721 tgaggcccgt tgttgtggcc gttgttgtgg ccgttgttgt gcccgttctg gtgaccgtgg
     6781 tggtgcttgc ggcccacatc ggcgcatacg ttgccgaacg cggggttcag caggccgatg
     6841 atgttgatcg agttgccgca gaggttgatc ggcacgtcga gaggcagctg cgctgcgttg
     6901 cccgagatga tgccgggcga gttgagagcc gagccctggg tgcccgagtc ggccgtcgcg
     6961 aggccggccc cgctgagcat cacggcggac gtgcccagcg cgacggcggc agccttcgcc
     7021 atgcgagaca tcgcgttctc cttcgttcga tgagccggcc gcccgtacgc ggccgcactc
     7081 tccttcaacg cgctcacgca ccgcgagtca cggcattcgt tagggatcac cccatttgaa
     7141 cagggttttt cccgtgcgcc ggggaatggg ccgggacggg acgaagggcg ggccatggtg
     7201 ggacgaggag cgcggcgggg cgggtcggag aacgggcggg gcggcgcgaa tgtgcgggtg
     7261 cgacgatcac cttcggccaa ccttgccccg cgcccgcgcg cgggcgcgct cgcggtatcc
     7321 ggccagcgga aaagccctcc cgagggaggg ctggatgtcg gacggccggt ggcgcccccg
     7381 gcaggactcg aacctgcggc caagcgctta gaaggcgcct gctctatcca ctgagctacg
     7441 ggggccgggt gtggtggcct ctgtcgtggt gcccgggtgt gggctgatcc gtgacgttgc
     7501 cggggacaag gatagggctc ccgcgtccgt gtccctgttg cttcgcctcc gtggctcaat
     7561 gtggaggttc agtgaagcgg tcctgataat cgcaggcagg tacgaatcgt gcatcgcttt
     7621 tcgcgtctcg cgcaccgggt gttgtgcact cgttatgcct gagtcccagt agtcccttcc
     7681 gtcccttgtg ttctgtcggc gcgctgacgt gttcatatgc ttcaaaatgc catcaaaatt
     7741 gggcattctt cgcgtgtggt gactctggac gtacggcctc agctcctcga cgcactctcc
     7801 gccctgcgcg accgtgtcgc cgccgtgcgc tacccgctgc ccctcgcggg ggccccacgc
     7861 gcgcgagcca accgcgacga actgctcgca cagctcgacg actacctggt gccccggctg
     7921 agagagcccg aagcgccgtt gctcgccgtc gtgggcggtt ccacaggcgc cgggaagtcg
     7981 accctcgtca actccctcgt gggccggagg gtcagcgagg cgggggtgct gcgccccacc
     8041 acccgcactc cggtgctcgt gtgccacccg ggggatcacc actggttcag cgggatgcgc
     8101 gtgctgcccc atctcacgcg cgcgtgggtg ccccgtcggg agcccggtgg cgagccgttc
     8161 ccggacggcg gcgacggtcg gcgcgtcctg cggatcgaga ccgccgacag cctgcccccc
     8221 gggctggccc tcctcgacgc gcccgacgtc gactccctca tcaccgagaa ccgcgtcctg
     8281 gccgccgaac tgatctccgc ggccgacatc tgggtgatgg tcaccacagc agcccgttac
     8341 gccgacgccg tgccctggca tctgctgcgc acggccaagc agcacagggc gaccctgatc
     8401 accgtgctcg accgggtgcc ccaccaggtg gtgtccgagg tctcacggca gtacggggca
     8461 ctgctcgcca aggccggcct cggcgaggtg cctcggttca ccgtgcccga gctgcccgaa
     8521 tccgcctggg gcggcgggct gctgccggcc acggccgtgg cgccgctgcg cagctggctg
     8581 acacaccagg cgaccgaccc cggggcccgg caccaggcga tggcacgcac cgctcacggc
     8641 gtactcgact cgctcagggc acggatgccc gagctcgccg gagctgccgc cgcccagtac
     8701 gcggccgcgc tgcggctcac cgcggccgtc gacacggcgt acgaccggga gcacacgcgc
     8761 gtgaagagga gtctgcagag cggggccgta ctcgccgggg acgcgctcaa gaggtggcgc
     8821 ggctacccgc tggactgcac cgccggagaa ctcctcgacg cgctcgtgga gagcctcgcc
     8881 gcgctgctgc tgtgcgccgt catcgccgcc gaccagtgcg tcgacgacgc ctggcgacgg
     8941 gagccggccg cgggcgcccc ggaactgacg cgccgcgacc cggtgctgga gagcgccgag
     9001 caccgcatcg ggatggccgt acgacgctgg cggcgcgtcc tggaggagta cgccgaggag
     9061 gaggcgcgcg acctcggcgg aagcaccacg ccggatcccg aggccctggc ggcactggtc
     9121 gcgaccgcgc tcctgggcgg gcgccgggtg cggtccgcgg gggaacggct ggccgagctg
     9181 atcggcgcgc acggtgccct ccggctgcgc gaccggggcg ggcggctgct caccgagtac
     9241 ctcggcaggg cgctgcgcgt cgagcgtgag cgtcggctcg ccccgctcga ggcactcgac
     9301 gtgactcccg aaccccaggt cgaactgatc gccgcgctgt ccgtactgca gaaggagaga
     9361 tgactgccgt gaccgccgtc accgaccgca cggaccacga cgggggcgaa aagggtgccc
     9421 gcgcgcgcgt gcatcccgat gctccggcct cgcgccccga cgacccgccc ccgcgctccg
     9481 atggcacggc ctcacgcggg gacgcccctg cgcagaccgg tgccgatgcc gatgccgatg
     9541 ccgatgccga cgccgggacc gagaccgagg ccgaggtgga cgcgtatgcg cacgcggacg
     9601 cggagggcag accccgggac gggagccagt gggacgacgg cctgatcgcc cgacgcgcga
     9661 ctgacgagga gcccgcccag caggccacgc aaaccgcaca gaccgggcaa gccgaacagg
     9721 cgggacagac ggctcaggca gcccaggcgg cgcagggcga cctggcgaag tccgggccga
     9781 ccggcacgca gatcgtgttc cccgtcgcct acgacgtacc gctgcggtcg cggctggacg
     9841 agtttcggga gcttgtgggt gtctcccgcg cgcgtctcga cagcgggacg ctcgccgagg
     9901 cgggacgtgt cctggacgag gcagccgcgc ggcgcaggct ctccgggcag cacaccgtcg
     9961 tggccctcgc gggagcgacc ggcagcggca agtcgacgct cttcaacgcg ctcgcgggcg
    10021 cccctctctc ggacaccggc ctccgccgcc ccacgaccgc cacgcccatc gtgtgcagct
    10081 ggagcgacgg cgcgggcagt ctcatcgacc ggctgggagt accggggcgg ctgcgccgcc
    10141 gcccgctgga gggcgtggag ggggagtcgg cgctgcgcgg gctggtcctg gtggacctgc
    10201 cggaccacga ctccgcggcg gtgcagcacc gcgagcaggt ggaccgcatc ctggcgctgg
    10261 tggacgcggt catctgggtc gtcgacccgg agaagtacgc cgacgccgtc ctccacgagc
    10321 gctatctgcg gcccctggcg gggcacgcgg aggtgatgtt cgtggtcctc aaccaggtgg
    10381 accggctgcc cggggaagcc gcccaccagg tcctcgacga tctgcggagg ctgctcgacg
    10441 aggacgggat cgcggtgggg gagtacggcg aaccgggcgc gaccgtgctc gccctgtccg
    10501 cgcttaccgg ggacggggtc ggagagctgc gcgaggcgct cggccggttc gtggcggagc
    10561 agggtgcccc ggcccgccgt gtcgccgccg a
//
