LOCUS       NZ_BMVW01000003        21248 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces poonensis strain JCM 4815 sequence03, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVW01000003
VERSION     NZ_BMVW01000003.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces poonensis
  ORGANISM  Streptomyces poonensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 638423)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 137X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650915.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:27:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,577
            CDSs (total)                      :: 7,501
            Genes (coding)                    :: 7,228
            CDSs (with protein)               :: 7,228
            Genes (RNA)                       :: 76
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 273
            CDSs (without protein)            :: 273
            Pseudo Genes (ambiguous residues) :: 0 of 273
            Pseudo Genes (frameshifted)       :: 96 of 273
            Pseudo Genes (incomplete)         :: 224 of 273
            Pseudo Genes (internal stop)      :: 19 of 273
            Pseudo Genes (multiple problems)  :: 60 of 273
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:46:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 83957
            Orig. end                         :: 105205
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVW01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21248
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21248
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21248
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11248](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11248)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(851..866)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.79"
                     /tool="antismash"
     misc_feature    complement(1588..1599)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.99"
                     /tool="antismash"
     misc_feature    1790..1804
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.22"
                     /tool="antismash"
     misc_feature    1804..1818
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.65"
                     /tool="antismash"
     misc_feature    complement(1906..1921)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.55"
                     /tool="antismash"
     gene            complement(1927..2793)
                     /locus_tag="IE242_RS10575"
                     /old_locus_tag="GCM10010365_21900"
     CDS             complement(1927..2793)
                     /NRPS_PKS="Domain: Thioesterase (32-249). E-value: 1.9e-43.
                     Score: 141.5. Matches aSDomain:
                     nrpspksdomains_IE242_RS10575_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010357641.1"
                     /locus_tag="IE242_RS10575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_21900"
                     /product="thioesterase II family protein"
                     /protein_id="WP_189857753.1"
                     /sec_met_domain="Thioesterase (E-value: 6e-43, bitscore:
                     142.6, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.2e-08, bitscore:
                     30.0, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGRPRAHEPVRSGTAVSRWLLRRTVLPDPALRMICFPHAGGAAT
                     FFHGWQDRVPPGVEVAAVCYPGRQSRIVEPPLTSMDELADGIHAVLGEVLDRPLALFGH
                     CMGAVVAYEVAVRLAERDGVGPAALLVSGHPAPHLCASGPPLPTAVDDTEIVALATAVD
                     PLLRASPELLDLALPALRADHTLLRAYRPARCPVIPVPVVGYRGVDDPRTTDGDMRAWS
                     ALTSSGFRLRTLPGDHFYLVARQADLVADAMDTVTAAQRGGHGSNRQARDQRVTDQRTS
                     VQHGRNQ"
     aSDomain        complement(2047..2697)
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS10575_Thioesterase.1"
                     /evalue="1.90E-43"
                     /label="IE242_RS10575_Thioesterase.1"
                     /locus_tag="IE242_RS10575"
                     /protein_end="249"
                     /protein_start="32"
                     /score="141.5"
                     /tool="antismash"
                     /translation="RMICFPHAGGAATFFHGWQDRVPPGVEVAAVCYPGRQSRIVEPPL
                     TSMDELADGIHAVLGEVLDRPLALFGHCMGAVVAYEVAVRLAERDGVGPAALLVSGHPA
                     PHLCASGPPLPTAVDDTEIVALATAVDPLLRASPELLDLALPALRADHTLLRAYRPARC
                     PVIPVPVVGYRGVDDPRTTDGDMRAWSALTSSGFRLRTLPGDHFYLVARQADLV"
     CDS_motif       complement(2440..2505)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE242_RS10575_0001"
                     /evalue="7.80E-09"
                     /label="NRPS-te1"
                     /locus_tag="IE242_RS10575"
                     /protein_end="118"
                     /protein_start="96"
                     /score="28.0"
                     /tool="antismash"
                     /translation="RPLALFGHCMGAVVAYEVAVRL"
     misc_feature    complement(3628..3642)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.04"
                     /tool="antismash"
     misc_feature    3771..3789
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.24"
                     /tool="antismash"
     gene            complement(3923..5803)
                     /locus_tag="IE242_RS10580"
                     /old_locus_tag="GCM10010365_21920"
     CDS             complement(3923..5803)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015580045.1"
                     /locus_tag="IE242_RS10580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_21920"
                     /product="CocE/NonD family hydrolase"
                     /protein_id="WP_189857755.1"
                     /transl_table=11
                     /translation="MKRRRTAAWAASALVATLTFTGTLTVPAATAQERAQARPGSVATA
                     TDPVTHEENDRVPEGSVWTQHYFPSSDGSGTELHADVLLPEGLRKGKRVPVILSVGPYF
                     GHSGQTGPEGWTHTGPSSRFQDFIEGADVFDNGYAFVMVDLRGFGGSTGCLDWAGPGEQ
                     ADVKAAIDWAAKQPWSTGKVGMYGKSYDAVTGLIGNNLDQRALKAVVAQEPVWDMYQYI
                     YSNGVPRPNVTGTAGAYNSIATTAPLADDDPRYQANARYEESHPECLTENSAGYRIADQ
                     RDPHWKARDLAKLAEGSDTPLFVTQGFIENNTKPEEMEEYLDNHRGVERGWLGQWDHVR
                     GGDRVSDGRLAMGREGWYEETLSFFDQYLKGVRPAVRYPAYVVEDNTGAWRAQKKWPVV
                     ERSVTLPLGGGSYVDDGGASASAALAESGDAAPRTLDKPSPYGEWDMENAPRTDRVAPK
                     GLAGEQAERQQAGETTSSFFVWSKPLKRDVRVTGTPRVSLTARGEGNVMLKLYDVAPDG
                     TAVMFDEQVSLLDSGRLAVDLKATDWTLAAGHVLAVEIGSVQTGSWRDTPSGETIEVRG
                     AQLKLALDDPADDVATAGDRSPFLDTYLRQYTVNLPAGPGTFTVVPGGRL"
     misc_feature    6046..6060
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.8"
                     /tool="antismash"
     gene            complement(6065..6793)
                     /locus_tag="IE242_RS10585"
                     /old_locus_tag="GCM10010365_21930"
     CDS             complement(6065..6793)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.5"
                     /locus_tag="IE242_RS10585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_21930"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_229858732.1"
                     /transl_table=11
                     /translation="MTSLIGPDGAGKSILLTLLGRLTDPTSGTVPLDGADVHRASSTEI
                     VRKLAALRQENHSTVRVTVRDLVALGRFPHGRGRLTPEGVVHIDRALDFLDLAGLSGRH
                     LDQLSGGRRQRAHVAMVLAQDTDYVPLDEPLNNLGIKHGVRMTERLRAGADDLGKTVVL
                     VVHDIDIAAGHPDRILALRDGALAAHGTPAELMDPEIPSGIFDTPGRVHEVGRAAAGRP
                     SPLRWPSAGHIGNTLYTSRR"
     misc_feature    complement(6808..6825)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.69"
                     /tool="antismash"
     gene            6929..7735
                     /locus_tag="IE242_RS10590"
                     /old_locus_tag="GCM10010365_21940"
     CDS             6929..7735
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015423.5"
                     /locus_tag="IE242_RS10590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_21940"
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="WP_189857758.1"
                     /transl_table=11
                     /translation="MTLVLSLDGLDAATRWLDLAGVLVCALLGGVVARAEGLDLFGYLA
                     VGTVSGLGGGIVRDTLLQHGTPVALTDPAYLPVAFAGAFLAFVFSIGEELWHRMFVVLD
                     AAVIGFWSVAGAQKTLAAGLAWLPAVLLGTITAVGGGAVRDLLLRRVPAVFGGNGLYAT
                     VALAVSGAYVLLHRTGHPGAAVVCGVLLAVVFRVVAYRRGWYLPGGLPLEPRTAVHAVR
                     RSTRRAGGTVRRTAGTAGRTVGAARNRVLRKSRTVRKNNRTKGPTS"
     gene            7732..9015
                     /locus_tag="IE242_RS10595"
                     /old_locus_tag="GCM10010365_21950"
     CDS             7732..9015
                     /GO_function="GO:0004180 - carboxypeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244: amidohydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605057.1"
                     /locus_tag="IE242_RS10595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_21950"
                     /product="amidohydrolase"
                     /protein_id="WP_189857760.1"
                     /transl_table=11
                     /translation="MTSSSTSSSPLGTVLAGLPGIRDAAEAFYKDLHAHPELGLDEHRT
                     AGRVAERLRHWGYRVTEGIGGTGVVGVLANGEGPTVLFRADMDALPVQEATGLPYASTV
                     TTTGPGGHAQPVMHACGHDMHITCLLGFAALMAEAKDVWQGTVVALFQPSEERGDGADA
                     MLDDGLVDRIPRPDVAFAQHVLPLPAGCVGVRPGPFLSAADNLRITLFGRGAHGSMPQA
                     GIDPVVMAAMCVVRLQTIVSRELAPTTPAALTVGSIVAGTSPNVIPESAVIELNIRTYD
                     DTTRRTVLDAVRRCVDAEAAASGAPKEPLIERLGEFPPTVNDAGVAERLDRAFRAHFGD
                     DAGTIALQTASEDFSKIPDAFGIPFAYWGIGCVDPGTYRTAAGRGTVQQDIPVNHSPAF
                     APVVQPTLDTGVSALTVAALAWLGGKNT"
     gene            complement(9060..9932)
                     /locus_tag="IE242_RS10600"
                     /old_locus_tag="GCM10010365_21960"
     CDS             complement(9060..9932)
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009077433.1"
                     /locus_tag="IE242_RS10600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_21960"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_189857762.1"
                     /transl_table=11
                     /translation="MPTSPARTTATDSVLRTDYQRSVAEYWNTHRQDPANLRLGEVDGL
                     YHHHYGVGDYDPLVLEGPQDTRDRRVIEELHRLETAQADLLLDHLGRILPGDKLLDAGS
                     GRGGTSFMAHARFGCEVDGVTISEYQAGFANEQAVRRGVADKVRFHLRNMLDTGFATGS
                     RRAVWTDESTMYVDLSELYTEFSRLLGYGGRYVCVTGCSNDVTGMRSKAVSRIDEHYTC
                     NIHPRSEYFRALAANNLVPIRVVDLTAATIPYWELRARSSVATGIEEAFLTAYKENSFH
                     YLLIAADRI"
     gene            complement(10001..11248)
                     /locus_tag="IE242_RS10605"
                     /old_locus_tag="GCM10010365_21970"
     CDS             complement(10001..11248)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019890277.1"
                     /locus_tag="IE242_RS10605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_21970"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_189857764.1"
                     /sec_met_domain="T1TS (E-value: 7e-50, bitscore: 165.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLISRCLAPVARHGLAESVAALLLDPRRPGRRDVLTPVPSTGVP
                     ATGAVPAGPAPAGPTPAARPFAVTGPTGLGTSAARLWARRPPAQPSRGQGEQGASPVLY
                     CPPAVRDDPALGEAVNDRLVAWAEETGIYPGRLDTVRSADFGRLIMLAHPETDDPDRLL
                     AAAKCALSEWAVDDHYLDGEAEEPHPELLGRRLAIAHSVVDQAHLPLRYAPELERVVRD
                     DPVMVALRSALGGLATYVTTTQVQRLRHELAIMFVAYNQEAVWATAGHTPPVWEFLTHR
                     HENSFVPCMVLVDAVAGYQLPQAEFADPRVRRAFTMAGSASVIVNDLYSMAKEDPTDFS
                     LPRLIAAEERCSLREAVDRTVELHDELMHTYETEAAALARTGSPELRRFLAGVWAWLGG
                     SREWHAGTARYTATAA"
     gene            complement(11254..12675)
                     /locus_tag="IE242_RS10610"
                     /old_locus_tag="GCM10010365_21980"
     CDS             complement(11254..12675)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019058032.1"
                     /locus_tag="IE242_RS10610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_21980"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_189857766.1"
                     /transl_table=11
                     /translation="MSVETGTTRAQDPEEREQQSLSTAAARNLATTTKTRPQMQAITSR
                     WLTRMLPWVNVAGGTYRVNRRLAYVVGDGRVSFVQTGAQVQVVPAELTELPLLRGFDDA
                     DVLKALAERFTQREFEPGQAIVESGGRADHVYLIAHGKVEKVGAGPYGGEAVTGFLADG
                     DSLGGRVLAGAEGTWDFTARALTPTTVLELPYPAYQAVAGQHEKLREHVRRRRADEDKS
                     LNKSGEADLAVTSGHTGEPTLPGTFADYELRPREYELGVAQTVLRVHSRVADLYNDPMD
                     QTGQQLRLTVEALYERREYELVNNPDFGLLHNADFDQRISTHSGPPTPDDLDELLSMRR
                     GTRFLFAHPRAIAAFGRECNKRGIYFTPVELDGHHLPAWRGVPLLPCSKIPVSAAGVSS
                     VLALRTGEDDEGVVGLHQVGIPDEYEPGLNVRFMGIDDQAVISYLVSTYFSAAALVPDA
                     LGLLENVETARANGS"
     misc_feature    12768..12782
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.56"
                     /tool="antismash"
     misc_feature    complement(12769..12784)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.25"
                     /tool="antismash"
     gene            complement(12934..14052)
                     /locus_tag="IE242_RS10615"
                     /old_locus_tag="GCM10010365_21990"
     CDS             complement(12934..14052)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009716085.1"
                     /locus_tag="IE242_RS10615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_21990"
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="WP_189857768.1"
                     /transl_table=11
                     /translation="MLTNAVQRAQDILVRPFSLGSLSLPNRVVMAPMTREFSPGGVPGE
                     DVARYYARRAAGGVGLIITEGTYVGHASAGNSARVPHFHGDEALAGWSAVAEAVHREGG
                     RIMPQLWHVGMDRTAGNPPVPDAPRIGPSGIALDGSHAGQEMTRADIDDVVAAYASAAA
                     SAEALGFDGVEIHGGHGYLVDQFLWSRTNRRTDGYGGDVARRTRFAAEIVAACRAAVSD
                     DFPISFRLSQWKVNNYQARIAETPQELETVLGLLAEAGADIFHCSTRRFHLPEFEGSDL
                     NLAGWAKKVSGKPAISVGSVGLSNEFLQVFQGEQARVTDIADLLDRMEREEFDLVAVGR
                     ALLGDPEWLTKILAGRVDELTPFHVGLVGSLH"
     gene            complement(14249..15832)
                     /locus_tag="IE242_RS10620"
                     /old_locus_tag="GCM10010365_22000"
     CDS             complement(14249..15832)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020556318.1"
                     /locus_tag="IE242_RS10620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_22000"
                     /product="MDR family MFS transporter"
                     /protein_id="WP_229858734.1"
                     /transl_table=11
                     /translation="MNDRPTPTPTAPGRAALPRLGVFGLMLGIFLANLDGQIVSTALPT
                     IVGDLGGLEHFSWSVTAYLLTMAAATPLWGKLGDLYGRKGAYSSSVVVFLVGTVLCGLA
                     QNMGQLIAFRALQGIGAGGLMVGALSVIGVLVPPQERGRIQSMVGVMLPISFVGGPLLG
                     GFITDCLDWRWTFYVNVPIGLVALLAVAKGVRLPAQRVTGRVDYLGAALLTSGILALTL
                     LAGWAGSTYAWTSWQIAALAVVVVASLAWFVRVERRAPEPITPPRLFTSREFTLAQVLS
                     FLVGAVLVSVINYLPQYMQFVQGATPTVSGMLILPLMLGMLAAQLTTGRLMDRGGLDRI
                     VPLTGGVVTVVGALLLLLLGTDTPVAAASALTLAVGIGVGILMQSTLLSTMNNAAPRDM
                     GAATGTVTLVRTIGGSLGVAVLGAVHSSRMGDVLAERLGSDAEQRLTSGGELTPALLED
                     LSDQVRHTVEDAVSSGLHGVVVGAAVLSVLTFATAWFIRPAPAADPADAAPTAPGGAPG
                     KDSVRTSPAD"
     gene            complement(15863..16462)
                     /locus_tag="IE242_RS10625"
                     /old_locus_tag="GCM10010365_22010"
     CDS             complement(15863..16462)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010987067.1"
                     /locus_tag="IE242_RS10625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_22010"
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="WP_189857770.1"
                     /transl_table=11
                     /translation="MADATGGPLRIAVIIGSTRDGRFGPVVADWITGHIAEREDMTADV
                     VDLVETPLPTVFPAFGQTPSDEVVAQLGAVSPRLAEADAFVIVTPEYNHSFPAPLKNAI
                     DWHNEQWHGKPVGFVSYGGLAGGLRAVEQLRVVLAELHAVTVRNTVSFHNYGEVFNADG
                     KPSDPGCDVAAKALLDQLTWWGHALREARRARPYAV"
     gene            16615..17352
                     /locus_tag="IE242_RS10630"
                     /old_locus_tag="GCM10010365_22020"
     CDS             16615..17352
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014180486.1"
                     /locus_tag="IE242_RS10630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_22020"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_189857772.1"
                     /transl_table=11
                     /translation="MPSQERRVRTEDQEHVSVWERLGRPAPAPRTTLTPRRIARAAVGI
                     ADAEGLDAVTMRRLATELGVAPMAAYRYVTGKDELIELMVDFVYGELELPDGSEGWRTT
                     MRTLALRIREVLLRHSWVTRATWCAPTPSQLAVPESALAALDGLGLDADTAMAVYSTVT
                     AYVHGAVDSEVGLTQLLRVRGWSSREEARSGLASQMAWLLSTGSFPMYERYIGEADRKD
                     DLLWQFETGLDCVLDGISARLEI"
     gene            <17483..17694
                     /locus_tag="IE242_RS10635"
                     /pseudo=""
     CDS             <17483..17694
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003963469.1"
                     /locus_tag="IE242_RS10635"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="NDP-hexose 2,3-dehydratase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="HSEEGGRFLDAESRYLLVEADERDARSTRRPAPPGSPPTS"
     gene            17830..18042
                     /locus_tag="IE242_RS10640"
                     /old_locus_tag="GCM10010365_22030"
     CDS             17830..18042
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE242_RS10640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010365_22030"
                     /product="hypothetical protein"
                     /protein_id="WP_189857774.1"
                     /transl_table=11
                     /translation="MDRAFTPPAGFVPLIGLHTGITTEEIRLEPADQVAATVGAFVTAV
                     RAGSAPRTDTLRQAVLPDAVRRRSA"
     misc_feature    complement(18061..18075)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: strong, score: 28.31"
                     /tool="antismash"
     misc_feature    18098..18114
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.91"
                     /tool="antismash"
     misc_feature    complement(18148..18161)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.15"
                     /tool="antismash"
     gene            18273..19697
                     /locus_tag="IE242_RS10645"
                     /old_locus_tag="GCM10010365_22040"
     CDS             18273..19697
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008744487.1"
                     /locus_tag="IE242_RS10645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_22040"
                     /product="glycosyl hydrolase"
                     /protein_id="WP_268249443.1"
                     /transl_table=11
                     /translation="MRKIRHRLTSALAAAAALATLFAWSATQSAEAFPASSKQTVLNYL
                     RSVSGNHIISGQHNKEPASSPGQYTQQVKDVTGQYPGLWGGDLMFAAADVANRQRVVDQ
                     AKTEWANGSLVALTWHVCPPTGGSTCAFEGGVKSNISAAQFSQIITDGTALNTAWKRRL
                     DEAVPYLQQLKNAGVPVLFRPLHEMNESWNWWGNRPGANGSARLYQITRDYLAGTKGLD
                     NLIWVWNVQDNPAGGWSNYYPGDHYVDVVSLDVWYKNHPSSADYQQMRSIAGTKPMALA
                     EMGKMPTASLLESQPQWAWFMMWSEQLRGNNTNAEIQAAYFHSRVLNQGEITLPSSSGG
                     GTGSSTGAITGFGSKCVDVRASGTANGTAVQLYTCATGVAQTWTAPGDGTLRNPGSGRC
                     LDVSGAGTANGTPVQIWDCNGSGAQQWQYDSSTRALRNPASGRCLDVTGNTSADGTRLQ
                     IWDCTGGANQQWSLPS"
     gene            complement(19718..20413)
                     /locus_tag="IE242_RS10650"
                     /old_locus_tag="GCM10010365_22050"
     CDS             complement(19718..20413)
                     /NRPS_PKS="Domain: Abhydrolase_1 (15-150). E-value:
                     1.3e-15. Score: 49.6. Matches aSDomain:
                     nrpspksdomains_IE242_RS10650_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020114233.1"
                     /locus_tag="IE242_RS10650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010365_22050"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_189857778.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 8.6e-18, bitscore:
                     60.7, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1.4e-10, bitscore: 36.2,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLATRVWGDGPRTAVLVHGIMTDSRTWRRVAPAIAEHGYRVVAV
                     DLRGHGASGATDTYTSDPYTPATLAADLLDTLPPAPDLAIAHSLGSAALLLAVPGLRCA
                     RAVHCDPAWLRRPRDLDALRAVKHATWRELRAAHPRWHHDDITDEQRALATWDPESVEA
                     LLHLPGLPDTAPAVPSLVLLADPSERVPPAEAATLRRCGWQVRTVDGAGHTVHRDDPAG
                     FLAGLRGWL"
     aSDomain        complement(19964..20368)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE242_RS10650_Abhydrolase_1.1"
                     /evalue="1.30E-15"
                     /label="IE242_RS10650_Abhydrolase_1.1"
                     /locus_tag="IE242_RS10650"
                     /protein_end="150"
                     /protein_start="15"
                     /score="49.6"
                     /tool="antismash"
                     /translation="VLVHGIMTDSRTWRRVAPAIAEHGYRVVAVDLRGHGASGATDTYT
                     SDPYTPATLAADLLDTLPPAPDLAIAHSLGSAALLLAVPGLRCARAVHCDPAWLRRPRD
                     LDALRAVKHATWRELRAAHPRWHHDDITDEQ"
     misc_feature    20727..20741
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
ORIGIN
        1 gacggcgccg gtgtctgcgt tgaggacccg gtacgccccg atggcgcccg tcgagcccga
       61 cgcctcccga atgttgatct tggagacggt ggtggcggac ccccacttga ccgagacgga
      121 accggtcgag ccggccggcg accagtaggt gctcaggtca ccgtcccgca cgttgccgta
      181 gctcgtcccg tcggccttgc tggagccgtc ggagccggcg ccgatgctga ggttggtgcc
      241 ggtgggggga tcggtcgggt ccggcgtggg gtcggtgggg tcgggcgtgg ggtcggtcgg
      301 gtccggggtg ggcgtcgggt tctgcggcga gcagctgccg tcggagacct tcaggccctt
      361 gttggcgccc gccgtctggc tcacgacact cggcacgcag ttggccgcgt cgaggctgta
      421 ggcgtagggg atgctgacgc tggtgttgga ctgcgggttc gggccggccg ggttgttgtc
      481 ctcgccgggc tcggaccagg tcacgttgtc gaagatgttg ccgctgacct gccagtagcc
      541 ggccgcgtcg gtgtagaagg tgccgaggac gtccttggag tcctcgaagt agttgttgtc
      601 caccttggcc ttggcgccgg cccgggagtt gatgccggac tcgttcaggc tcacgtagtg
      661 gttgttgtag atgtgggccg tgccgccgcg cagcaggggc gcccgggagt cgatgttctc
      721 gtacttgttg tggtggaagg tgatgaagct gttggaggtg tcgctctcgc tggacccgat
      781 gaggccgccg cggccggagt tgcgcagggt gctgtaggac agcgtcacgt acttggtgtc
      841 gtccttcatg tcgaagaggc cgtcgaagcc ctccgactcc ccgcccgacg cctccaggct
      901 gacgtggtcg acccagacgt tgcggacgcc gctctccatg ccgatggcgt caccgccgtt
      961 ggaggtgggc gagcccgact tcttgacgtt cttgacggtc acgttctgga tgatgatgtt
     1021 gctggactcg cggatgtgga tgcccagctg gtcgaagacg gctccgccgc cgaccccgac
     1081 gatcgtgacg ttgcttatct gcttgagctc gatcactccg gcggcggtgc tgcagctgct
     1141 gcccgacacc ttggcggtgt tgccgtggtt gatggtcccc tcgacctcga tggtgatcgg
     1201 ggtgctgctg gaggcccggc tgcacagggc ctggtggatc gcggtgcccg tggtggcccg
     1261 taccgtctgg ccgcccgcgc cgccggtggt gccgccgttc tgggtcgcgt agccggtggc
     1321 gctgccggtc accgccgccg acgccgtggg cgccgacagc accgcggtgg tcgcggccgc
     1381 ggcggccgcg gtggccagcg ccgcggtgag tctcagtgcg actggtcgtc tcatcctcgt
     1441 gtcccttcgg tcttctcgtg ctgggtcctg ctgctgcggc atgcccgggc gcatgtcgtg
     1501 ctcatgtcat gtcataggta cgcccgcacc cgcaggccgt tcgacgggga gcctcgcgcg
     1561 gggtggacag cggctcatgc gcgaggagaa agcgctttcc gccgcgagaa tagggtgacg
     1621 cccactcgac tgacaaggtt ccgtacggtt gcggaatgtg gtccgccgtt tcatgtacgt
     1681 gtccgaggac cgggtgcaca tgccgggccg gcgccgcgct cgacgccgtc gacgaagccg
     1741 gtaccgtcag cgagtatcag acgatgggca cggacgcgac cccgtagacc ctgttcagaa
     1801 atgtgaaact cagttcctcc acagaacatc gcagacgccg gcgccggcag gcgtcggcgc
     1861 agcgtgcgac cgtccgtgag agacgggcga acagcgggta cggcgggttc ggtctccgcg
     1921 tcacggtcac tggttccttc cgtgctgcac gcttgttcgc tggtccgtga ctcgctgatc
     1981 cctggcttgc cggttgcttc cgtgcccacc cctctgagcg gcggtcacgg tgtccatggc
     2041 gtcggccacc aggtctgcct gccgggcgac cagatagaag tggtccccgg gcagcgtgcg
     2101 cagccggaaa ccggagctgg tcagcgcgct ccacgcacgc atgtcaccgt ccgtggtccg
     2161 ggggtcgtcg acaccccggt aaccgaccac gggtacgggg atcacggggc agcgtgccgg
     2221 acggtaggcg cggagcaggg tgtgatcggc acgcagggcg ggcagggcca ggtccagcaa
     2281 ctcgggtgac gcccgcagga gcgggtccac ggcggtggcg agcgcgacga tctccgtgtc
     2341 gtccacggcg gtcggcagtg ggggaccgct cgcgcagaga tggggcgcgg ggtgcccgga
     2401 caccaggagg gccgccgggc ctacgccgtc gcgttccgcc agccggacgg ccacctcgta
     2461 cgcgaccacg gcgcccatac agtggccgaa cagcgccagc ggacggtcca gcacttcgcc
     2521 cagcacggca tggatgccgt cggcgagctc gtccatggag gtgagcggag gctcgacgat
     2581 cctgctctgg cgccccgggt agcagaccgc ggcgacctcc acgccgggtg gcacccggtc
     2641 ctgccagccg tggaagaagg tggcggcccc tccggcgtgg gggaagcaga tcatccgcag
     2701 cgccgggtcg ggcaggaccg tgcgccgcag cagccaccgt gagacggctg tcccggaccg
     2761 gacgggctcg tgggcgcggg ggcggccggt catgtggtct cctccggatc ggggccgcgg
     2821 gcttggcgat cccaggtcgg tggccctggg ttcggtggcc ctgggttcgg tggccctggg
     2881 ttcagggggc gtggattcag gagtcgtcgt ggtctcaggg gtcgtcgtgg tttcaggggt
     2941 cgtgggctcg acggatcgtg ggctcaggga tcgcgggctc ggcagccgtg gactcgacca
     3001 ccgcggactc aacggccatg ccggtcgggc ccagcggcgt actgcttgag ggccgtgagc
     3061 gtgtcgtgcg tgttctcagt ctcccggcgc gagaaggagc cgtgccgcct caatgcactg
     3121 gacgtgccga cgcggggtac gtcggcagcg gtccggggtg gtttcgcggc catatcgcat
     3181 cccctccgct ccgccgtgat ccgatgcgta ttcgaacgag gtcatggcca gaaaggtgac
     3241 atcgaattcg aaccaggtga tggaaacagt cggcatagca gtcgacatag cagtcgacac
     3301 ggaaaagtaa gtagccgggc acccggcaga ggcatccgga aaccgggtgc cagcctcgtc
     3361 gaggaggtgt caccggtcaa gcagggtttc tcgccacatc acctgtaccg acgcttgcgt
     3421 gaatcagcag caatccttcc gcattgaaca gcggatggtc gcggacagaa ttattccggt
     3481 gtcgcccgct gcggcgcacc actgcgggga atcggccagt tcagccgccc gctcgatacc
     3541 cgtcgccgac ggtgcccgcc acggcgaact ccgcgtcgcg tctctgatcg gatgcggcag
     3601 acctcggcgc tttccttgcc gtagccgaaa tgtgtgagca ttcgctcggc cagttgctgg
     3661 actttcacag cctcgttgca gctccgcctg cgaccaattc gctctccgtt cgcagagacg
     3721 gacagcttcg atgctgtctt ggtttctcag cggttggaac ggtcgcggtc atcgatgagg
     3781 ttcacctttc ccggtcctga cgacgaaccg gcgccggccc ggcgttccgc atggtgcccg
     3841 gaacgccgta gtggccggcg ccggcccgga gtatcagtga tggccgccgg gcatcagcgg
     3901 cggcccccgg agatcacgga gatcagaggc ggcccccggg aacgaccgtg aacgtcccgg
     3961 gaccggccgg caggttcacc gtgtactggc gcagatacgt gtccaggaac ggcgagcggt
     4021 caccggcggt ggcgacgtcg tcggccgggt cgtccagggc cagtttcagc tgcgcgcccc
     4081 tgacctcgat cgtctcgccg gagggcgtgt cgcgccacga gccggtctgg acggagccga
     4141 tctccacggc cagcacgtgc ccggccgcca gggtccagtc ggtcgccttg aggtcgacgg
     4201 ccaggcggcc cgagtccagc agggagacct gctcgtcgaa catgacggcg gtgccgtccg
     4261 gggcgacgtc gtacagcttg agcatgacgt tgccctcgcc cctcgcggtg agggagaccc
     4321 gcggggtgcc ggtgacgcgc acgtcccgct tcagcggctt ggaccacacg aagaagctgg
     4381 acgtggtctc accggcctgc tggcgctcgg cctgctcccc ggccaggccc ttcggggcga
     4441 cccggtcggt cctgggcgcg ttctccatgt cccactcgcc gtacggtgac ggcttgtcga
     4501 gcgtccgcgg tgccgcgtcg ccggactcgg ccagggccgc gctcgcggag gcgccgccgt
     4561 cgtccacgta cgagccgccg ccgagcggga gggtgacgga ccgttcgacg accggccact
     4621 tcttctgcgc acgccaggcg ccggtgttgt cctcgacgac gtaggccggg tagcggaccg
     4681 ccggcctgac acccttgagg tactgatcga agaaggagag cgtctcctcg taccagccct
     4741 cacggcccat ggccaggcgc ccgtcgctga cgcggtcgcc gccgcgcacg tggtcccact
     4801 ggccgagcca gccgcgctcg acaccccggt ggttgtcgag gtactcctcc atctcctcgg
     4861 gcttggtgtt gttctcgatg aagccctggg tgacgaacag cggggtgtca ctgccctcgg
     4921 ccagcttcgc gaggtcgcgg gccttccagt gcgggtcccg ctggtcggct atgcggtacc
     4981 cggccgagtt ctccgtgagg cactccgggt ggctctcctc gtaccgggcg ttggcctggt
     5041 agcgcgggtc gtcgtccgcc aacggggcgg tggtggctat ggagttgtac gcgccggcgg
     5101 tgccggtgac gttcgggcgg ggcacgccgt tcgagtagat gtactggtac atgtcccaga
     5161 cgggctcctg ggcgacgacc gccttgagcg cgcgctggtc caggttgttg ccgataaggc
     5221 ccgtgacggc gtcgtacgac ttgccgtaca tgcccacctt gccggtggac cagggctgct
     5281 tcgcggccca gtcgatcgcg gccttcacgt cggcctgctc gccggggccc gcccagtcga
     5341 ggcagccggt ggagccgccg aagccgcgca ggtccaccat gacgaaggcg tagccgttgt
     5401 cgaagacgtc ggcgccctcg atgaagtcct ggaagcggga cgagggtccg gtgtgcgtcc
     5461 agccttcggg gccggtctgc ccggagtgcc cgaagtacgg gcccacggac aggatgacgg
     5521 ggaccctttt gcccttgcgc agtccctcgg gcagcaggac gtcggcgtgc agttcggtgc
     5581 cggagccgtc cgaggacggg aagtagtgct gggtccagac cgagccctcc gggacgcggt
     5641 cgttctcctc gtgggtgacg gggtcggtgg cggtggccac cgaccccggg cgcgcctgtg
     5701 cacgctcctg cgccgtggcg gcggggacgg tgagcgtgcc ggtgaatgtg agggtggcga
     5761 cgagtgccga ggcggcccag gcggccgtgc gacgtctttt cacgtgctcc tcccggaatg
     5821 atgagtacgg ggtggtgcag gtggttccag tagtgctggt agtgccgttg gtgccggtag
     5881 tgccggtagt gccggtggtg cagcggcccc ggcccgcctt cggcgaggcg acgacgggcg
     5941 ggcgcacgga cggacgcggc gcacgcgcgc acgcgggacg ttgtgccgcg ggcgcgggtg
     6001 cgggcgcgaa ctcgagcgga ctcgggccga cgacgaggga tcctatgatc aacctgagaa
     6061 ttcgtcatcg gcgcgatgtg taaagcgtgt taccgatgtg acccgccgac ggccacctca
     6121 gcggtgatgg acggccggcg gccgcccgtc ccacctcgtg gacccggccc ggggtgtcga
     6181 agatgccgct cgggatctcc gggtccatca gctcggcggg cgtgccgtgg gccgcgagtg
     6241 ccccgtcgcg cagggccagg atgcggtcgg ggtgaccggc ggcgatgtcg atgtcgtgga
     6301 cgaccaggac cacggtcttg ccgagatcgt cggcgccggc ccggagccgt tccgtcatgc
     6361 gtacgccgtg cttgatgccg aggttgttca gtggttcgtc cagcgggacg tagtcggtgt
     6421 cctgggcgag caccatggcg acgtgggcac gctggcgccg gccgccggag agctggtcga
     6481 ggtggcggcc cgacagtccg gcgaggtcga ggaagtccag ggcgcggtcg atgtggacga
     6541 cgccctcggg ggtgaggcgg ccgcggccgt gcgggaaccg gccgagggcg acgaggtcgc
     6601 ggacggtgac gcggacggtg gagtggttct cctggcggag ggcggcgagc ttgcggacga
     6661 tctcggtcga ggacgcccgg tgcacgtcgg cgccgtccag cggcaccgtg cccgaagtgg
     6721 gatcggtcag ccgcccgagc agggtgagca ggatggactt gcccgcgccg tcggggccga
     6781 tcagcgaggt caccccgccg cacgcgtttt acctgttctt gacattgggt cacttgtcac
     6841 cgcaaagggc gccgttttgt gccgtttgcg cggaccggca gctcgtgctc agatccggta
     6901 ggtgacggtg gtgacggcag gtgaccggat gacactcgtg ctgtcgctgg acggcctcga
     6961 cgcggcgacg cgctggctgg acctggccgg tgtcctcgtc tgcgctctgc tggggggtgt
     7021 ggtcgcccgg gccgaagggc tggacctctt cggctacctc gcggtgggca ccgtctcggg
     7081 cctgggcgga ggaatcgtcc gagacacgtt gctccagcac ggcacgcctg tcgcgctcac
     7141 cgatccggcc tatctgcccg tcgctttcgc gggagcgttc ctggccttcg tcttctccat
     7201 cggcgaggag ctgtggcaca ggatgttcgt cgtgctggac gccgcggtga tcggtttctg
     7261 gtcggtcgcc ggcgcccaga agaccctcgc ggccgggctc gcgtggctgc ccgccgtgct
     7321 gctgggcacc atcacggccg tgggcggcgg cgccgtgcgc gacctgctgc tccggcgcgt
     7381 ccccgcggtc ttcggcggca acgggctgta cgcgaccgtg gctctggcgg tgtcgggcgc
     7441 gtacgtcctc ctccaccgga cgggccatcc cggcgcggcc gtcgtctgcg gagtgctgct
     7501 ggccgtggtc ttccgcgtgg tggcgtaccg gcggggctgg tacctgcccg gcgggctgcc
     7561 gctggaacct cgcaccgccg tgcacgcggt acgccgctcg acacggcgtg ccggcggcac
     7621 cgtgcggcgt accgccggca cagccgggcg tacggtcggc gccgcgcgca accgcgtcct
     7681 gcgcaagagc cggacggtcc ggaagaacaa ccgaacgaaa gggccgactt catgacctcg
     7741 tcctcgacct cgtcctcacc cctcggcacg gtgctcgccg ggctgcccgg gatccgggac
     7801 gccgccgagg cgttctacaa ggacctgcac gcccaccccg agctcggcct cgacgagcac
     7861 cgcaccgcgg gccgggtggc ggagcgtctg cgccactggg gctaccgggt gaccgagggc
     7921 atcgggggga cgggggtcgt cggcgtcctg gcgaacggcg aaggccccac cgtgctgttc
     7981 cgcgccgaca tggacgccct gcccgtccag gaggccacgg gcctccccta cgcctcgacg
     8041 gtgaccacga ccgggccggg gggccacgca cagccggtga tgcacgcgtg cggccacgac
     8101 atgcacatca cctgcctcct cggcttcgcc gcgctcatgg ccgaagcgaa ggacgtctgg
     8161 cagggcacgg tcgtcgctct cttccagccc tccgaggagc ggggcgacgg cgccgacgcc
     8221 atgctcgacg acggtctcgt ggaccgcatc ccccggccgg acgtcgcctt cgcccagcac
     8281 gtgctgccgc tccccgccgg ctgcgtgggc gtccggcccg gtcccttcct ctccgccgcc
     8341 gacaacctgc gcatcaccct cttcggacgg ggcgcccacg gctccatgcc acaggcgggc
     8401 atcgacccgg tcgtgatggc cgcgatgtgc gtcgtacgcc tgcagaccat cgtctcccgg
     8461 gaactggccc ccaccacacc ggccgcgctg accgtgggca gcatcgtcgc cggtaccagc
     8521 cccaacgtca tccccgagtc ggcggtgatc gagctcaaca tccgcaccta cgacgacacg
     8581 acccgcagaa cggtcctcga cgcggtccgg cgctgcgtcg acgccgaggc cgccgcctcg
     8641 ggcgcgccga aggagcccct gatcgagcgg ctcggcgagt tccccccgac cgtcaacgac
     8701 gcgggggtgg ccgagcggct ggacagggcc ttccgcgccc acttcggcga cgacgcgggg
     8761 accatcgcac tgcagacggc gagcgaggac ttcagcaaga tcccggacgc tttcggcatc
     8821 ccgttcgcct actggggcat cggctgcgtg gaccccggca cgtaccggac cgccgccgga
     8881 cgcggcaccg tccagcagga catcccggtc aaccactccc ccgccttcgc ccccgtcgtc
     8941 cagcccaccc tcgacaccgg tgtcagcgcg ctcacggtcg ccgccctggc ctggctcggc
     9001 gggaagaaca cctgatccga gcgccaggac ctcggccccg gcccgccgcc cggacccgtt
     9061 cagatgcgat cggccgcgat gagcaggtag tggaaactgt tctccttgta cgcggtcagg
     9121 aacgcctcct cgatgccggt ggcgaccgag gacctggccc gcagctccca gtacgggatg
     9181 gtcgcggcgg tcaggtcgac gacgcggatc gggacgaggt tgttggccgc cagggcccgg
     9241 aagtactcac tgcgcggatg gatgttgcag gtgtagtgct cgtcgatgcg gctgaccgcc
     9301 ttggaccgca tgccggtgac gtcgttggag cagccggtga cgcacacgta ccggccgccg
     9361 taccccagaa gccgggagaa ctcggtgtag agctcggaca ggtccacgta catggtgctc
     9421 tcgtcggtcc agaccgctcg ccgggatccg gtggcgaacc ccgtgtcgag catgttgcgg
     9481 aggtggaacc gcaccttgtc ggccacaccg cgccggacgg cctgctcgtt cgcgaagccg
     9541 gcctggtact cggagatcgt cacgccgtcg acctcgcagc cgaagcgggc gtgcgccatg
     9601 aagctggtgc cgccccttcc cgagccggcg tccagcagtt tgtcaccggg gaggatccgg
     9661 cctaggtggt ccaggagcag gtccgcctgg gcggtctcca ggcggtgcag ctcctcgatg
     9721 acacgccggt ccctcgtgtc ctggggaccc tccaggacca ggggatcgta gtcgccgacg
     9781 ccgtagtggt ggtggtagag gccgtccacc tcgccgaggc ggaggttggc cgggtcctgc
     9841 cggtgggtgt tccagtactc cgccaccgac ctctggtaat cggtgcgcag cacgctgtcc
     9901 gtggcggtcg tcctggcggg ggaagtgggc atggcggact ccttgtctcc gagcgtgggg
     9961 cgagaatcca gaggcggggg cggggaacca ggtgcggacg tcaggcggcg gtggccgtgt
    10021 agcgggccgt tccggcgtgc cactcgcggc tgccgccgag ccaggcccac actccggcga
    10081 ggaagcgacg cagctccggg ctgcccgtgc gggccagggc ggccgcctcg gtctcgtagg
    10141 tgtgcatcag ttcgtcgtgg agttccacgg tgcggtcgac cgcttcccgc agtgagcacc
    10201 gctcctcggc ggcgatcagc cggggcaggc tgaagtccgt cgggtcctcc ttggccatgg
    10261 agtacaggtc gttcacgatg acgctcgccg atccggccat ggtgaacgcc cggcgcaccc
    10321 ggggatcggc gaactcggcc tgcggcagct ggtagccggc caccgcgtcg accagcacca
    10381 tgcacggcac gaagctgttc tcgtgccggt gcgtcaggaa ctcccagacc ggcggggtgt
    10441 gtccggccgt ggcccagacg gcctcctggt tgtaggcgac gaacatgatg gccagctcgt
    10501 ggcggagccg ctgcacctgt gtggtcgtga catatgtggc gaggcccccg agggcggacc
    10561 tgagggcgac catgaccggg tcgtcccgca ccacgcgttc gagctcgggt gcgtagcgca
    10621 gcggcagatg ggcctggtcg acgaccgagt gggcgatcgc caggcgccgg ccgagcagtt
    10681 ccgggtgcgg ttcctccgcc tcgccgtcga ggtagtggtc gtcgacggcc cattcggaca
    10741 gcgcgcactt ggccgccgcc agcagccggt cggggtcgtc ggtctccgga tgggccagca
    10801 tgatgaggcg cccgaagtcc gccgagcgga ccgtgtcgag ccggccgggg tagatgccgg
    10861 tctcctcggc ccaggcgacc agccggtcgt tgaccgcctc gccgagggcg gggtcgtcac
    10921 ggacggcggg cggacagtac agcaccgggc ttgcgccctg ctctccctgg ccccgtgacg
    10981 gctgcgccgg cggccgccgg gcccacaggc gggccgcgga ggtgccgagt cccgtggggc
    11041 cggtgacggc gaacggccgc gcggccggcg tcggcccggc cggtgccggc ccggccggca
    11101 ccgccccggt cgccgggacc ccggtggacg gcacgggggt gaggacgtcc cggcggccgg
    11161 ggcgcctcgg gtcgagcagg agggcggcca ccgactccgc cagcccgtga cgtgccacgg
    11221 gcgccaggca gcgggagatc agcgacatcc ccgtcagctc ccgttcgcac gggcggtctc
    11281 gacgttctcc agcaggccca gcgcgtccgg caccagggcc gccgccgaga agtacgtact
    11341 gactaggtag gagatgacgg cctggtcgtc gatgcccatg aaccgcacgt tcagccccgg
    11401 ctcgtactcg tccgggatgc cgacctggtg caggccgacc acgccctcgt cgtcctcgcc
    11461 cgtgcgcagg gcgaggacgg acgacacgcc cgccgccgag accgggatct tgctgcacgg
    11521 cagcagcggc acgccccgcc aggcggggag gtggtgaccg tccagctcga ccggggtgaa
    11581 gtagatgccg cgtttgttgc actcgcggcc gaaggcggcg atcgcccgcg ggtgggcgaa
    11641 caggaagcgg gtgccgcgcc tcatgctcag cagctcgtcc aggtcgtccg gggtcggcgg
    11701 cccggagtgg gtcgagatcc gctggtcgaa gtcggcgttg tgcagcagcc cgaagtcggg
    11761 gttgttgacg agctcgtact cccggcgctc gtacagggcc tcgacggtca gccgcagttg
    11821 ctgcccggtc tggtccatgg ggtcgttgta gaggtcggcg acccggctgt gcacgcgcag
    11881 gaccgtctgc gccacgccca gttcgtactc gcgcggccgg agttcgtagt cggcgaaggt
    11941 gcccggcagt gtcggctccc ccgtgtgccc ggaggtcacc gccaggtcgg cctcacccga
    12001 cttgttcagg gacttgtcct cgtcggcacg ccgccgccgt acgtgctccc gcagcttctc
    12061 gtgctgtccg gcgacggcct ggtacgccgg gtacggcagc tccagcacgg tcgtgggggt
    12121 cagggcgcgg gcggtgaaat cccaggtgcc ctccgcgccg gcgagcaccc ggccgccgag
    12181 gctgtccccg tcggcgagga atcccgtgac cgcctcgccg ccgtacggcc ccgcaccgac
    12241 cttctccacc ttgccgtggg cgatcaggta cacgtggtcc gccctgccgc ccgactccac
    12301 gatggcctgg ccgggttcga actcgcgctg tgtgaacctc tccgccagcg ccttgagcac
    12361 atcggcgtcg tcgaagcccc gcagcagcgg cagttcggtc agctccgcgg gaacgacctg
    12421 gacctgcgcg ccggtctgga cgaagctcac ccgtccgtca ccgacgacgt acgccaggcg
    12481 gcggttgacc cggtacgtgc cccccgccac gttcacccag ggcagcatcc gcgtcagcca
    12541 acgcgaggtg atcgcctgca tctggggtcg ggtcttggtg gtcgtggcca ggttccgtgc
    12601 cgcggccgtg ctgagactct gctgttcccg ttcctcgggg tcctgtgccc gggtcgtacc
    12661 cgtctcgacc gacatcgact gcctctccgt cgttccgacc atgggtgaac ggcccggccg
    12721 agccgacgcg cgcggagcgc ggagcggtcg ggctttcggc tgcgccagga aattcatagt
    12781 catgacggaa atgactaaga aggccggtat gggccattcc tttccggtcg gacgcgccca
    12841 cgggccgccg gggccgcggc ccgccgggga cgtcacacac tccccccgag gccgcggccc
    12901 accgttccgc cgcggggccg gtggcggtgc gggtcagtgg aggctgccga ccaggcccac
    12961 gtggaacggg gtcagttcgt cgacgcggcc ggcgaggatc ttcgtcagcc actccggatc
    13021 gccgaggagc gcgcggccca ccgcgaccag gtcgaactcc tcgcgctcca tgcggtcgag
    13081 caggtccgcg atgtccgtga cgcgcgcctg ctccccctgg aacacctgga ggaactcgtt
    13141 gctcaggccc accgagccca cgctgatggc gggcttgccg gagaccttct tcgcccagcc
    13201 cgcgaggttg aggtcggagc cctcgaactc gggcaggtgg aagcgccggg tggagcagtg
    13261 gaagatgtcg gccccggcct cggccagcag tccgagcacg gtctccagct cctgcggggt
    13321 ctcggcgatc cgcgcctggt agttgttcac cttccactgg gagagccgga aggagatcgg
    13381 gaagtcgtcg gacacggccg cccggcaggc cgccacgatc tcggcggcga accgggtgcg
    13441 ccgggcgacg tcgccgccgt agccgtcggt acgccggttg gtgcgggacc acaggaactg
    13501 gtcgaccagg tagccgtggc caccgtggat ctccacgccg tcgaagccca gggcctcggc
    13561 cgacgccgcg gcggaggcat aggcggcgac cacgtcgtcg atgtcggccc gggtcatctc
    13621 ctggcccgcg tgcgagccgt ccagggcgat gccggaaggg ccgatccgcg gggcgtcggg
    13681 caccggcggg ttgccggccg tacggtccat gccgacgtgc cacagctgcg gcatgatccg
    13741 gccgccctcc cggtggaccg cctcggccac cgcggaccag ccggccagtg cctcgtcacc
    13801 gtggaagtgc ggcacgcggg cgctgttgcc cgccgaggcg tggccgacgt aggtgccctc
    13861 ggtgatgatc agtccgacgc cgcccgcggc ccgccgggcg tagtagcgcg ccacgtcctc
    13921 gcccggtacg ccgcccgggg agaactcgcg cgtcatgggc gccatgacca cacggttggg
    13981 caggctgagg ctgcccaggg agaagggacg gaccaggatg tcctgggcac gctgtaccgc
    14041 attagtgagc atcggttttc gccttcgaca gggagccgac cgcacggcgg cgggggattc
    14101 caccgtgcgg tcagtggctg ggatgggtga gtggtggtac tggtgcggcc tggccacccg
    14161 gtccgcggtg acgcggggat gtgggccggg cccgctcggg ccgtgcacgg cgcgcaggtc
    14221 tcccggtgcg ccgcgcggac ggccgtgttc agtccgccgg tgacgtacgg accgagtcct
    14281 tccccggggc gccgcccggg gccgtcggag cggcgtccgc cgggtcggcg gccggtgccg
    14341 ggcggatgaa ccacgccgtg gcgaacgtga gcaccgacag gacggccgcg ccgaccacga
    14401 ccccgtgcag tccgctgctg acggcgtcct cgacggtgtg ccgcacttgg tcggacaggt
    14461 cctccagcag ggccggggtc agctcgccgc cgctggtgag ccgttgctcc gcgtcggagc
    14521 cgagccgctc ggcgaggacg tcccccatgc ggctgctgtg cacggcgccg agcacggcga
    14581 caccgaggga gccgccgatg gtgcgcacca gggtgacggt gccggtggcg gcgcccatgt
    14641 cccggggggc ggcgttgttc atggtggaga gcagggtgct ctgcatcagg atgccgacac
    14701 cgatcccgac ggcgagggtc agggccgagg ccgcggcgac gggggtgtcc gtgccgagca
    14761 ggagcagcag cagcgcgccg acgacggtga cgacgccgcc ggtgagcggc acgatccggt
    14821 ccagtccgcc gcggtccatc agccgcccgg tggtcagctg ggccgccagc atcccgagca
    14881 tcagcggcag gatcagcatg ccgctgaccg tgggcgtggc gccctggacg aactgcatgt
    14941 actgcgggag gtagttgatg acggagacga ggacggcgcc gaccaggaag ctgagcacct
    15001 gggcaagggt gaactcccgg ctggtgaaca gccgcggcgg ggtgatcggt tcaggggcgc
    15061 gccgctccac gcggacgaac caggcgaggc tcgccacgac cacgacggcg agcgcggcga
    15121 tctgccagga cgtccacgcg taggtgctgc cggcccagcc ggcgagcagg gtgagcgcca
    15181 ggatgccgct ggtgagcagg gcggcgccca ggtagtcgac gcgccccgtg acacgttgcg
    15241 cgggcagccg tacgcccttg gcgacggcca gcagcgcgac gaggccgatg ggaacgttga
    15301 cgtagaacgt ccagcgccag tccagacagt cggtgatgaa tccgccgagc agggggccgc
    15361 cgacgaagga gatcggcagc atgacgccca ccatggactg gatacggccg cgctcctgcg
    15421 gcggcaccag gacgccgatc accgacagcg cccccaccat cagcccgccg gcgccgatgc
    15481 cctgcagagc acggaaggcg atgagctggc ccatgttctg ggccaggccg cacagcaccg
    15541 tgccgaccag gaagaccacc acggagctgc tgtaggcgcc cttgcggccg tacaggtcgc
    15601 cgagtttgcc ccacaggggt gtggcggcgg ccatggtgag cagatacgcc gtcaccgacc
    15661 aggagaagtg ctcgagtccg ccgaggtcgc ccacgatcgt gggcagcgcg gtgctgacga
    15721 tctgcccgtc gaggttcgcc aggaagatgc cgagcatcag tccgaagacg cccaggcggg
    15781 gcagggcggc ccggccgggt gcggtgggag tgggtgtcgg gcggtcgttc atcgctgccc
    15841 cccaggcaga ggtggtggga cgtcagacgg cgtaggggcg ggcacgcctg gcctcgcgca
    15901 gggcgtgccc ccaccaggtg agctggtcga gcagggcctt ggccgcgacg tcgcagccgg
    15961 ggtcgctcgg cttgccgtcg gcgttgaaga cctcgccgta gttgtggaag ctgacggtgt
    16021 tgcggacggt gacggcgtgc agttccgcca ggaccacgcg gagctgctcg acggcgcgca
    16081 ggccgccggc cagaccgccg taggagacga agcccaccgg cttgccgtgc cactgctcgt
    16141 tgtgccagtc gatggcgttc ttcagcggcg ccgggaagct gtggttgtac tccggggtga
    16201 cgatcacgaa ggcgtcggcc tcggccagcc gcggcgacac cgcgccgagc tgcgccacca
    16261 cctcgtcgga gggggtctgc ccgaaggcgg ggaacacggt gggcagcggg gtctcgacga
    16321 ggtcgaccac gtcggccgtc atgtcctcgc gttcggcgat gtggccggtg atccagtcgg
    16381 cgacgaccgg gccgaaccgg ccgtcccggg tactgccgat gatcaccgcg atgcgcaggg
    16441 ggccgccggt cgcgtcagcc atgggaaaca cctccgtgtg tgcgacgccg tgtgtgtacg
    16501 gcgtactctg gatgtacaac gtacacacgg tcgcgtacat cgtccaccac ttctatacgg
    16561 cgtacgcggc cggtacgctg tacacagcac cgcccggagg aaggaaccca cgcgatgccc
    16621 tcccaggagc gacgggtacg gaccgaggac caggagcacg tctccgtgtg ggaacgcctc
    16681 ggacgcccgg cacccgcccc ccgcaccacc ctcacccccc gacggatcgc ccgagccgcg
    16741 gtcggcatcg ccgacgccga agggctggac gcggtcacca tgcgccgcct ggccaccgaa
    16801 ctcggcgtcg cccccatggc cgcgtaccgc tatgtgacgg gcaaggacga actcatcgag
    16861 ctgatggtcg acttcgtcta cggcgagctg gagctgccgg acggctccga gggctggcgc
    16921 accaccatgc gcacgctcgc tctgcgcatc agggaggtcc tcctgcggca ctcctgggtc
    16981 acccgggcca cctggtgcgc cccgaccccg agccagctgg ccgtacccga gtccgccctg
    17041 gccgcgctcg acggcctcgg gctggacgcg gacacggcga tggcggtcta cagcaccgtc
    17101 accgcgtacg tgcacggcgc ggtcgactcg gaggtcggcc tgacccagct gctgcgggtg
    17161 cgcggctggt ccagccgcga ggaggcccgg tccggactgg cctcgcagat ggcctggctg
    17221 ttgagcaccg gcagcttccc gatgtacgag cgctacatcg gcgaggccga ccgcaaggac
    17281 gacctgctgt ggcagttcga gaccggcctg gactgcgtcc tcgacggcat ctccgcccgc
    17341 ctggagatct gaggacatct cccgaacagg tcactcggaa aaacagcagg cccgctacag
    17401 atgatgtaca tgtagcgggc cttggcttgt ccgttccgga actccgaaac aggttcgcct
    17461 cacttctacg gcggtggggg aacactctga ggagggcggc cggttcctcg acgccgagag
    17521 ccggtatctg ctcgtcgagg ccgacgagcg ggacgcccgc tcgacccgcc gcccggctcc
    17581 gcccgggtca cccccgacca gctgacctgg ctggtccggc acggccacta cctgaatgtg
    17641 caggcccgta cgccgccggc ttgcctcgac gccgaccggg cggccgcccg atgagcgcgc
    17701 cggtgcgtat cggggtgctc ggctgtgcgg accgcctgca ccgcgtcgtc gtcgaacagc
    17761 tccgcgtacg gccctgatgg agaacgtgat gttcgtccat catccccggc acgcgaaggg
    17821 cggatcacgg tggaccgggc gttcaccccg ccggccggct tcgtgcccct gatcggtctg
    17881 cacacgggca tcaccacgga ggagatccgg ctggaacccg ccgaccaggt cgcggcgacg
    17941 gtcggcgcct tcgtcaccgc ggtccgcgcc gggtccgcgc cccgcacgga caccctgcgg
    18001 caggccgtcc tgccggacgc cgtccgccgc cggtccgcat gacggaactc acgctgggac
    18061 ggggccggtc ggcccccgaa agggacgcgg ccaggagata cccatatcgg ggacaagtgg
    18121 ccagattccc cacgaggttt aggaaaagtt aagtaaacaa taccgccggg aggttgcgga
    18181 aagccacgcg ggccattgac gagcgtcatg aaagaagcca tcttcatcgc gagaagaagc
    18241 tcgttcgatg aaccgcgaaa gctgggatgc ccatgcgaaa aatccggcac cgactcactt
    18301 ccgccctggc cgccgcggcc gcccttgcga cactgttcgc ctggtcggcg acacaatccg
    18361 cggaggcgtt ccccgcgtct tccaagcaga ctgtgctgaa ctatctgcgc tccgtttccg
    18421 gaaaccacat catttccggc cagcacaaca aggagcccgc ctcgtcgccc gggcagtaca
    18481 cacagcaggt caaggacgtc accgggcagt atcccggtct gtggggcggg gacctgatgt
    18541 tcgccgccgc cgacgtggcc aaccgccagc gggtggtgga ccaggcgaag acggagtggg
    18601 cgaacggctc gctggtcgcc ctgacctggc atgtctgccc gccgaccggc ggtagcacct
    18661 gcgcgttcga gggcggcgtg aagtcgaaca tatcggctgc gcagttctcg cagatcatca
    18721 ccgacggcac tgcgctgaac accgcgtgga agcggcgcct cgacgaggcc gtcccctatc
    18781 tccagcaatt gaagaacgcg ggcgttcccg tcctcttccg cccgctccat gagatgaacg
    18841 aatcatggaa ctggtgggga aaccggcccg gagcgaacgg cagtgcgcgc ctctaccaga
    18901 tcactcggga ctacctcgcc ggaaccaaag ggctggacaa tctgatctgg gtctggaacg
    18961 tacaggacaa cccggccggc ggctggagca attactaccc cggcgaccat tacgtggatg
    19021 tcgtctcgct ggacgtctgg tacaagaatc accccagttc cgccgactac cagcagatgc
    19081 ggagcatcgc ggggacgaag cccatggccc tcgcggaaat gggcaagatg ccgaccgctt
    19141 cgctgctgga gagccagccc cagtgggcct ggttcatgat gtggtccgag cagttgcgcg
    19201 ggaacaacac caacgccgag atccaggcgg cgtacttcca ctcccgcgta ctgaaccagg
    19261 gcgagatcac ccttccctcc tcctccggcg gaggcaccgg atccagcacc ggagccatca
    19321 ccgggttcgg ctcgaagtgc gtggacgtcc gggcctccgg caccgccaac ggcaccgccg
    19381 tgcagctgta cacgtgcgcg accggtgtcg cccagacctg gaccgcgccg ggcgacggca
    19441 cactgcgcaa ccccggctcc ggaaggtgcc tggatgtctc cggcgccggc acggcgaacg
    19501 gcacccccgt ccagatctgg gactgcaacg ggtccggcgc ccagcagtgg cagtacgaca
    19561 gctccacgcg ggctctgcgc aaccccgcgt cgggtcgctg cctggacgtc accggcaaca
    19621 cgtccgccga cggcacccgg ctccagatct gggactgcac cggcggtgcc aaccagcagt
    19681 ggtcgctgcc ctcctgatcc cgccggtccc cgcccggtca cagccagccg cgtagaccgg
    19741 cgaggaagcc ggccgggtcg tcacggtgga cggtgtgccc cgcaccgtcc accgtgcgca
    19801 cctgccagcc acagcggcgc agggtcgcgg cctcggccgg cggtacccgc tcactcggat
    19861 cggcgagcag gacgagcgag gggacggccg gggcggtgtc cggcaggccg ggcaagtgca
    19921 ggagggcctc gacggactcc gggtcccagg tggcgagggc tcgctgctcg tccgtgatgt
    19981 cgtcgtggtg ccagcggggg tgtgcggcac gcagctcccg ccaggtggcg tgcttgacgg
    20041 cgcgcagggc gtccaggtcc cggggccggc gcagccacgc ggggtcgcag tggacggcgc
    20101 gggcgcagcg cagaccggga acggcgagca gcagggcggc cgatcccagc gagtgggcga
    20161 tggcgaggtc gggggccggg ggcagggtgt cgagcaggtc ggcggccagc gtggcggggg
    20221 tgtacgggtc agaggtgtac gtgtcggtgg cgccgctcgc gccgtggccg cgcaggtcga
    20281 cggcgacgac ccggtaaccg tgctcggcga tggccggggc gacacggcgc caggtgcggg
    20341 agtccgtcat gatgccgtgc accaggacgg ccgtgcgcgg tccgtcgccc cagacccgcg
    20401 tcgcgagcct catgaggcgg cgccgagggg cacccgggcg cgatagagca ccgctcccgt
    20461 accggtcgcc accactgtgc aggggcaccc ggccggtacg aacgcggcgg cgccgggacg
    20521 gagggccgga ccgggcgtca gacacacctc gccggcgagg cagagcagca cttggggacc
    20581 gggttcggtc aggcgcacgg cttcggcgcc cgcctccacg tccacgcgcg agagggcgaa
    20641 ctccgcggcg ggtgaccggt actgcctctc gccctgtacg ccggtgggcg tgggccgtat
    20701 cacggacggc cgcccggggg tgaggtcgac gatgtcggcc agcagggcgg tgtcgacgtg
    20761 tttgtcggtc aggccgcagc gcagcacgtt gtcggagttg gccatgatct ccgctcctgt
    20821 cccccgcagg taggcgtgcg gcacacccgc ccccaggtac agggcctcgc ccgcgtcgag
    20881 gcggacatgg ttgagcagca gagccgcgag cagcccgggg tcaccgggga agtcgtccgc
    20941 caccgcggcg tacgcggcgg cggtggtgcg ccaggggttc cgggacgcgg ccagccggcg
    21001 cagggcggtg gacacggcgt gcaccaggcg ctccggggcg tcgagggccg cgcggagcgt
    21061 gtgcccgagg gcttccaccg gcggccgcga gcgcagcagg gcggcccggt tccggagttc
    21121 gggcaccgac agggcatcga gcaggtcggc tgtgcgggcc gggtcgcgga agccgcagag
    21181 cgcctcgaac gaacccaggg cgcagagcag ttccggcttg tggttgcggt ccttgaaggt
    21241 gcggtgcg
//
