LOCUS       NZ_BMVR01000037        15670 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces flavofungini strain JCM 4753 sequence37, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVR01000037
VERSION     NZ_BMVR01000037.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces flavofungini
  ORGANISM  Streptomyces flavofungini
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 15670)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650815.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:46:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,873
            CDSs (total)                      :: 7,799
            Genes (coding)                    :: 7,638
            CDSs (with protein)               :: 7,638
            Genes (RNA)                       :: 74
            rRNAs                             :: 1, 1, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 161
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 161
            Pseudo Genes (frameshifted)       :: 43 of 161
            Pseudo Genes (incomplete)         :: 137 of 161
            Pseudo Genes (internal stop)      :: 10 of 161
            Pseudo Genes (multiple problems)  :: 26 of 161
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:42:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 15670
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVR01000037.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..15670
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     gene            <1..10433
                     /locus_tag="IE274_RS38730"
                     /old_locus_tag="GCM10010349_79090"
     source          1..15670
                     /culture_collection="JCM:4753"
                     /db_xref="taxon:68200"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces flavofungini"
                     /strain="JCM 4753"
                     /submitter_seqid="sequence37"
                     /type_material="type strain of Streptomyces flavofungini"
     cand_cluster    1..15670
                     /SMILES="C(C)C(O)C(C)C(O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..15670
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[<4:>15670](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      <5..>15670
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     CDS_motif       <7..104
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0001"
                     /evalue="1.30E-19"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE274_RS38730"
                     /protein_end="33"
                     /protein_start="0"
                     /score="62.8"
                     /tool="antismash"
                     /translation="VLFSSAAGVLGSAGQANYAAANAFLDALAQHRR"
     CDS             <5..10433
                     /NRPS_PKS="Domain: ACP (156-228). E-value: 3.2e-31. Score:
                     99.5. Matches aSDomain: nrpspksdomains_IE274_RS38730_ACP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (255-681). E-value:
                     5.9e-184. Score: 603.8. Matches aSDomain:
                     nrpspksdomains_IE274_RS38730_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (793-1089). E-value: 2.3e-108.
                     Score: 354.0. Matches aSDomain:
                     nrpspksdomains_IE274_RS38730_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_KR (1438-1617). E-value: 1.7e-61.
                     Score: 199.3. Matches aSDomain:
                     nrpspksdomains_IE274_RS38730_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1722-1807). E-value: 2.1e-29.
                     Score: 93.7. Matches aSDomain:
                     nrpspksdomains_IE274_RS38730_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (1830-2258). E-value:
                     1.7e-178. Score: 585.8. Matches aSDomain:
                     nrpspksdomains_IE274_RS38730_PKS_KS.2"
                     /NRPS_PKS="Domain: PKS_AT (2375-2669). E-value: 4.8e-109.
                     Score: 356.2. Matches aSDomain:
                     nrpspksdomains_IE274_RS38730_PKS_AT.2"
                     /NRPS_PKS="Domain: PKS_KR (3030-3209). E-value: 4.2e-58.
                     Score: 188.2. Matches aSDomain:
                     nrpspksdomains_IE274_RS38730_PKS_KR.2"
                     /NRPS_PKS="Domain: PKS_PP (3307-3393). E-value: 2.3e-30.
                     Score: 96.8. Matches aSDomain:
                     nrpspksdomains_IE274_RS38730_PKS_PP.2"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (3404-3475). E-value:
                     3.2e-23. Score: 74.4. Matches aSDomain:
                     nrpspksdomains_IE274_RS38730_PKS_Docking_Cterm.1"
                     /codon_start=3
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491081.1"
                     /locus_tag="IE274_RS38730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_79090"
                     /product="type I polyketide synthase"
                     /protein_id="WP_190120650.1"
                     /sec_met_domain="PP-binding (E-value: 8e-16, bitscore:
                     45.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 2.8e-233, bitscore:
                     761.3, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 8.1e-96, bitscore:
                     307.5, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.8e-09,
                     bitscore: 24.2, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.6e-110, bitscore:
                     356.2, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 9.5e-63, bitscore:
                     198.4, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLFSSAAGVLGSAGQANYAAANAFLDALAQHRRAQGLPATSLAWG
                     LWADQGGMAGALADEDIDRMNRAGVAALSADEGLALLDASLAEPDGALVPMKLHLDTLR
                     RQFGADVPPLFRSLIRGGGRTRRVVESGPAAAGTSLADQLVALAPENRERALLDLVRAQ
                     VAAVLGYASGDDVAPTKAFKELGFDSLTSVELRNRLNSATELRLPASLVFDYPTPKVLA
                     QYLGTEILGDLAAAPGAATGRSAQTAVAAQDEPIAIVAMSCRFPGGVHTPEDLWRLLTD
                     GEEAITEFPEGRGWDTASLYDPDPNRVGTSYAREGGFLHDAGEFDAAFFGISPREALAM
                     DPQQRLLLETSWEAIERAGIDPATLHGSPTGVFAGLIYHEYGSQLASVPEDLGGYLGTG
                     SSGAIASGRISYSFGLEGPAVTVDTACSSSLVALHLAAQALRQGECSLALAGGVTVMPT
                     AGTFLEFSRQRGLAPDGRCKPFAAAADGTSWGEGVGMLVLERLSDAQRNGHQVLAVVRG
                     SAINQDGASNGLTAPNGPSQQRVITQALANARLTTTDVDAVEAHGTGTPLGDPIEAQAL
                     IATYGKERPADQPLLLGSVKSNIGHTQAAAGVAGVIKMVMAMRHGVLPRTLNMDAPTPE
                     VDWSAGTVELLAESRAWPERDGGAPRRAGVSSFGVSGTNAHVILEQGPSAAAPEAAGVA
                     PSPVVAGVVPLALSAKTEGALRDQAARLRAHLLADAGLELGDVAWSLAVSRSRFEYRGV
                     VLGGDRDELLAGLDRLAQDDASAQNVVTGRALGGSARPVFVFPGQGSQWTGMARELLDS
                     SPVFAARMRECADALSEFVDWDLIEELNGERFDHVDVVQPVLFAVMVSLAEAWRAAGVQ
                     PAAVVGHSQGEIAAACVAGALSLRDAARVVALRSLAIRELSGKGGMVSVPLPEAEVREL
                     ITAWGDRVSVAAVNGPAQVVVSGEPDALEELVAQCVARDVRARTIPVDYASHSAYVEQI
                     EARIAEALAGVAPQAAEVPLYSTLTGEWLGANTPMDAGYWYRNLRQTVLFEHATRGLLA
                     EGHDLFLEMSPHPVLTVPVQATIEAAGREGAAVALGSLRRDDGGADRLAASLAEAHTHG
                     AELDWQALLPGARATVDLPTYAFQRQHYWLLSPEQEAGAEPTPAVDEVEARFWEAVERE
                     DLAGLAAELEVADGSAAGLGEVLPVLSSWRRQRREKSTVDGWRYRVTWKSLASGALPGP
                     VLTGRWLVVVPEEAAAHPWVAGVTEALAQAGADVTEVRVSGAELNRETLAGRLREQLTP
                     DGPEPVGVVSLLALAEDPHPEQPVLPAGLAGTVALVQALGDVEVDAKLWAVSSGAVSTG
                     RNDQVESPAQAQTWGLGRVVALEHPERWGGLVDLPATPDSRAAARFAGILAGVGDEDQL
                     AVRGSGVFVRRLVRAEPAAAAKDKTAASAQDKWTPRGTVLITGGTGALGPHMARWLARE
                     GAEHLVLTSRRGPAAPGADELRTKLEELGVQVTIAACDVADRDAVAALLDQLTADGHTL
                     RAVIHAAALIELAPIATTTLDEFAEIVAAKVAGAVVLDELLDGADLDAFVLFSSIAGVW
                     GSGDHAAYAAANAHLDALAEHRRARGLTATSIAWGVWNVVNPYLSGSAPIDVDPEQLRR
                     QGLPFLDPDLAFAGMRQTLDDDETFLALADVDWDQFVPVFTSRRARPLLADLPDAQRVL
                     ASQGGTDSAEDGGDTPSKAAALRERLTGLAGPEQNRVLLDLVLTHAAAVLGYESAQALD
                     PERAFREFGFDSLTAVDLRNRLGAGTGLKLPTTVVFDHPNGTALAAYLRTQVLGADKAA
                     TAAPVATVAAATDEPIAIVAMSCRYPGGISSPERMWEVLEGRADVVGGYPANRGWDIAH
                     LYDPDPETPGTTTTRGGGFLHDAGAFDPAFFGISPREALAMDPQQRLLLETSWEAFERA
                     GVDPRAVRGEAAGVFVGTNYQDYGTGPGQVSAGSEGHILTGSAPSVISGRIAYSFGLEG
                     PAVTVDTACSSSLVAMHLAAQALRQGECSLALAGGVAVMSSPGALIAFSQQRGLADDGR
                     CKAFAAAADGMGMAEGVGMVLLERLSDAQRNGHQVLAVVRGSAINQDGASNGLTAPNGP
                     SQQRVIRQALANARLTPADVDAVEAHGTGTTLGDPIEAQALLATYGQERPDSGEPLWLG
                     SIKSNIGHSQAASGVAGVMKMVLAMHHGVLPQTLHVDEPTPEVDWTEGAVALLTEARDW
                     PERGDAPRRAGVSSFGMSGTNAHVILEQLPAAEQPQPVGADSDDGAAVPSPVVAGVVPL
                     ALSAKSEGALRDQAARLREHLVTRGSLELDDVAWSLAVSRSRFEHRGVVLGRDRDELLA
                     GLDALTQEDAAATQVVSGRALGGIVRPVFVFPGQGSQWAGMARELLDSSPVFADRMREC
                     ADALSEFVEWDLLEELSGDNFDRVDVVQPVLFAVMVSLAATWQAAGVQPAAVVGHSQGE
                     IAAACVAGALTLRDAARVVALRSLAIRELSGKGGMVSVPLPEAEVRELIAAWGGRIELA
                     AVNGPAQVVVSGEPEALEELVAQCVAQDIRARTIPVDYASHSSYVEQIEEQIAEALAGV
                     DPQAAEVPLFSTLTGEWLDANTPMDSGYWYRNLRQTVLFEHATRGLLTEGHGLFLEMSP
                     HPVLTVPVQATIDATDSQAVTLGSLRRDDGGANRLLASIAEAHAHGAELDWAALYPGAR
                     ATVDLPTYAFQRDHYWLLAPQEEEQPEGAPLATDEVESRFWDAVEREDLEGLAAELDVA
                     DGPAAELGAVLPVLSSWRRQRRERATLDSWRYQVAWEPLAGELPAAGPTGRWLVVVPEE
                     PQRQGAPEQADGSQAWRAAVIEALAQSGAQVHELRVPAGEMTREALAERLRELAAADPA
                     EPTGVLSLLALDESALDESATGAGARADQPGVPAALGGTFTLVQALGDAGIGARLWAVT
                     RGAVATGPADPAALPAQAQVWGLGRVAALECPDRWGGLVDVPQDPDKRAVSQLVGILAG
                     AGDEDQLAVRQAGVLVRRFVRAPLGAGEAREWSPRGTALVTGGTGAIGGHVARWLAREG
                     VEHLVLTSRRGPDAPGAAELKAELEELGAKVTVAACDVADRDAVAGLLGRLVEDGHTLR
                     SVFHAAGVGQGQPLAETTAADIAAVLEAKVAGAAHLDALLDTDELDAFVLFSSNAGVWG
                     SGSQGAYAAANAHLDALAERRRARGLTATSVAWGLWAGGGMAGDDGEEQFRRRGLRPMA
                     PDLAVAALAQAVAHDETFVAVADLDWERFAPAFTSARTSPFIGDLPEVRRYARSVAAEP
                     AADAGTGDDAAAGLRRRLAPLTEPEREVILLDIVRTHAAAVLGYTGAESVDAHRAFREL
                     GFDSLTAVEVRNRLNKATGLRLPATLVFDYPTSVVLAQYLRTQLLQDDAAGVDSTLQEL
                     DRLEAGLSSIAPDDSARMRITMRLEALMSKWKGADAEAPADGEEVSSRLESASADEVFD
                     FIDKELGIS"
     misc_feature    20..36
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.42"
                     /tool="antismash"
     aSDomain        474..689
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38730_ACP.1"
                     /evalue="3.20E-31"
                     /label="IE274_RS38730_ACP.1"
                     /locus_tag="IE274_RS38730"
                     /protein_end="228"
                     /protein_start="156"
                     /score="99.5"
                     /tool="antismash"
                     /translation="LDLVRAQVAAVLGYASGDDVAPTKAFKELGFDSLTSVELRNRLNS
                     ATELRLPASLVFDYPTPKVLAQYLGTE"
     aSDomain        771..2048
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38730_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="5.90E-184"
                     /label="IE274_RS38730_PKS_KS.1"
                     /locus_tag="IE274_RS38730"
                     /protein_end="681"
                     /protein_start="255"
                     /score="603.8"
                     /tool="antismash"
                     /translation="IAIVAMSCRFPGGVHTPEDLWRLLTDGEEAITEFPEGRGWDTASL
                     YDPDPNRVGTSYAREGGFLHDAGEFDAAFFGISPREALAMDPQQRLLLETSWEAIERAG
                     IDPATLHGSPTGVFAGLIYHEYGSQLASVPEDLGGYLGTGSSGAIASGRISYSFGLEGP
                     AVTVDTACSSSLVALHLAAQALRQGECSLALAGGVTVMPTAGTFLEFSRQRGLAPDGRC
                     KPFAAAADGTSWGEGVGMLVLERLSDAQRNGHQVLAVVRGSAINQDGASNGLTAPNGPS
                     QQRVITQALANARLTTTDVDAVEAHGTGTPLGDPIEAQALIATYGKERPADQPLLLGSV
                     KSNIGHTQAAAGVAGVIKMVMAMRHGVLPRTLNMDAPTPEVDWSAGTVELLAESRAWPE
                     RDGGAPRRAGVSSFGVSGTNAHVILEQ"
     aSModule        771..5426
                     /complete
                     /domains="nrpspksdomains_IE274_RS38730_PKS_KS.1"
                     /domains="nrpspksdomains_IE274_RS38730_PKS_AT.1"
                     /domains="nrpspksdomains_IE274_RS38730_PKS_KR.1"
                     /domains="nrpspksdomains_IE274_RS38730_PKS_PP.1"
                     /locus_tags="IE274_RS38730"
                     /monomer_pairings="mmal -> Me-ohmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       1026..1052
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0002"
                     /evalue="6.50E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="IE274_RS38730"
                     /protein_end="349"
                     /protein_start="340"
                     /score="6.6"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     CDS_motif       1254..1301
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0003"
                     /evalue="1.90E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE274_RS38730"
                     /protein_end="432"
                     /protein_start="416"
                     /score="19.8"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     CDS_motif       1677..1721
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0004"
                     /evalue="1.20E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE274_RS38730"
                     /protein_end="572"
                     /protein_start="557"
                     /score="11.3"
                     /tool="antismash"
                     /translation="VEAHGTGTPLGDPIE"
     CDS_motif       1782..1826
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0005"
                     /evalue="1.60E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE274_RS38730"
                     /protein_end="607"
                     /protein_start="592"
                     /score="11.1"
                     /tool="antismash"
                     /translation="GSVKSNIGHTQAAAG"
     CDS_motif       2379..2435
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0006"
                     /evalue="7.40E-10"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE274_RS38730"
                     /protein_end="810"
                     /protein_start="791"
                     /score="30.4"
                     /tool="antismash"
                     /translation="VFVFPGQGSQWTGMARELL"
     aSDomain        2385..3272
                     /ASF="Methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38730_PKS_AT.1"
                     /evalue="2.30E-108"
                     /label="IE274_RS38730_PKS_AT.1"
                     /locus_tag="IE274_RS38730"
                     /protein_end="1089"
                     /protein_start="793"
                     /score="354.0"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGSQWTGMARELLDSSPVFAARMRECADALSEFVDWDLIEE
                     LNGERFDHVDVVQPVLFAVMVSLAEAWRAAGVQPAAVVGHSQGEIAAACVAGALSLRDA
                     ARVVALRSLAIRELSGKGGMVSVPLPEAEVRELITAWGDRVSVAAVNGPAQVVVSGEPD
                     ALEELVAQCVARDVRARTIPVDYASHSAYVEQIEARIAEALAGVAPQAAEVPLYSTLTG
                     EWLGANTPMDAGYWYRNLRQTVLFEHATRGLLAEGHDLFLEMSPHPVLTVPVQATIEAA
                     GREGAAVALGSLRRD"
     CDS_motif       2538..2606
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0007"
                     /evalue="6.30E-10"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="IE274_RS38730"
                     /protein_end="867"
                     /protein_start="844"
                     /score="31.1"
                     /tool="antismash"
                     /translation="DHVDVVQPVLFAVMVSLAEAWRA"
     CDS_motif       2610..2720
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0008"
                     /evalue="4.20E-19"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="IE274_RS38730"
                     /protein_end="905"
                     /protein_start="868"
                     /score="60.3"
                     /tool="antismash"
                     /translation="GVQPAAVVGHSQGEIAAACVAGALSLRDAARVVALRS"
     CDS_motif       2826..2864
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0009"
                     /evalue="3.90E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE274_RS38730"
                     /protein_end="953"
                     /protein_start="940"
                     /score="13.7"
                     /tool="antismash"
                     /translation="AAVNGPAQVVVSG"
     CDS_motif       2934..2966
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0010"
                     /evalue="1.10E-02"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="IE274_RS38730"
                     /protein_end="987"
                     /protein_start="976"
                     /score="8.9"
                     /tool="antismash"
                     /translation="VDYASHSAYVE"
     CDS_motif       3075..3122
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0011"
                     /evalue="1.10E-04"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="IE274_RS38730"
                     /protein_end="1039"
                     /protein_start="1023"
                     /score="14.5"
                     /tool="antismash"
                     /translation="MDAGYWYRNLRQTVLF"
     CDS_motif       3165..3194
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0012"
                     /evalue="2.10E-02"
                     /label="PKSI-AT-mM_m9"
                     /locus_tag="IE274_RS38730"
                     /protein_end="1063"
                     /protein_start="1053"
                     /score="7.9"
                     /tool="antismash"
                     /translation="FLEMSPHPVL"
     aSDomain        4320..4856
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38730_PKS_KR.1"
                     /evalue="1.70E-61"
                     /label="IE274_RS38730_PKS_KR.1"
                     /locus_tag="IE274_RS38730"
                     /protein_end="1617"
                     /protein_start="1438"
                     /score="199.3"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: A2"
                     /tool="antismash"
                     /translation="GTVLITGGTGALGPHMARWLAREGAEHLVLTSRRGPAAPGADELR
                     TKLEELGVQVTIAACDVADRDAVAALLDQLTADGHTLRAVIHAAALIELAPIATTTLDE
                     FAEIVAAKVAGAVVLDELLDGADLDAFVLFSSIAGVWGSGDHAAYAAANAHLDALAEHR
                     RARGLTATSIAWGVWN"
     CDS_motif       4323..4421
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0013"
                     /evalue="1.50E-15"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE274_RS38730"
                     /protein_end="1472"
                     /protein_start="1439"
                     /score="49.7"
                     /tool="antismash"
                     /translation="TVLITGGTGALGPHMARWLAREGAEHLVLTSRR"
     CDS_motif       4701..4811
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0014"
                     /evalue="9.00E-18"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE274_RS38730"
                     /protein_end="1602"
                     /protein_start="1565"
                     /score="56.8"
                     /tool="antismash"
                     /translation="LDAFVLFSSIAGVWGSGDHAAYAAANAHLDALAEHRR"
     aSDomain        5172..5426
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38730_PKS_PP.1"
                     /evalue="2.10E-29"
                     /label="IE274_RS38730_PKS_PP.1"
                     /locus_tag="IE274_RS38730"
                     /protein_end="1807"
                     /protein_start="1722"
                     /score="93.7"
                     /tool="antismash"
                     /translation="LTGLAGPEQNRVLLDLVLTHAAAVLGYESAQALDPERAFREFGFD
                     SLTAVDLRNRLGAGTGLKLPTTVVFDHPNGTALAAYLRTQ"
     aSDomain        5496..6779
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38730_PKS_KS.2"
                     /domain_subtypes="Modular-KS"
                     /evalue="1.70E-178"
                     /label="IE274_RS38730_PKS_KS.2"
                     /locus_tag="IE274_RS38730"
                     /protein_end="2258"
                     /protein_start="1830"
                     /score="585.8"
                     /tool="antismash"
                     /translation="IAIVAMSCRYPGGISSPERMWEVLEGRADVVGGYPANRGWDIAHL
                     YDPDPETPGTTTTRGGGFLHDAGAFDPAFFGISPREALAMDPQQRLLLETSWEAFERAG
                     VDPRAVRGEAAGVFVGTNYQDYGTGPGQVSAGSEGHILTGSAPSVISGRIAYSFGLEGP
                     AVTVDTACSSSLVAMHLAAQALRQGECSLALAGGVAVMSSPGALIAFSQQRGLADDGRC
                     KAFAAAADGMGMAEGVGMVLLERLSDAQRNGHQVLAVVRGSAINQDGASNGLTAPNGPS
                     QQRVIRQALANARLTPADVDAVEAHGTGTTLGDPIEAQALLATYGQERPDSGEPLWLGS
                     IKSNIGHSQAASGVAGVMKMVLAMHHGVLPQTLHVDEPTPEVDWTEGAVALLTEARDWP
                     ERGDAPRRAGVSSFGMSGTNAHVILEQLP"
     aSModule        5496..10184
                     /complete
                     /domains="nrpspksdomains_IE274_RS38730_PKS_KS.2"
                     /domains="nrpspksdomains_IE274_RS38730_PKS_AT.2"
                     /domains="nrpspksdomains_IE274_RS38730_PKS_KR.2"
                     /domains="nrpspksdomains_IE274_RS38730_PKS_PP.2"
                     /locus_tags="IE274_RS38730"
                     /monomer_pairings="mmal -> Me-ohmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       5751..5777
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0015"
                     /evalue="6.50E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="IE274_RS38730"
                     /protein_end="1924"
                     /protein_start="1915"
                     /score="6.6"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     CDS_motif       5979..6026
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0016"
                     /evalue="1.90E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE274_RS38730"
                     /protein_end="2007"
                     /protein_start="1991"
                     /score="19.8"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     CDS_motif       6402..6446
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0017"
                     /evalue="1.10E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE274_RS38730"
                     /protein_end="2147"
                     /protein_start="2132"
                     /score="11.4"
                     /tool="antismash"
                     /translation="VEAHGTGTTLGDPIE"
     CDS_motif       6510..6554
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0018"
                     /evalue="5.20E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE274_RS38730"
                     /protein_end="2183"
                     /protein_start="2168"
                     /score="9.7"
                     /tool="antismash"
                     /translation="GSIKSNIGHSQAASG"
     CDS_motif       7125..7181
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0019"
                     /evalue="4.70E-10"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE274_RS38730"
                     /protein_end="2392"
                     /protein_start="2373"
                     /score="31.0"
                     /tool="antismash"
                     /translation="VFVFPGQGSQWAGMARELL"
     aSDomain        7131..8012
                     /ASF="Methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38730_PKS_AT.2"
                     /evalue="4.80E-109"
                     /label="IE274_RS38730_PKS_AT.2"
                     /locus_tag="IE274_RS38730"
                     /protein_end="2669"
                     /protein_start="2375"
                     /score="356.2"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGSQWAGMARELLDSSPVFADRMRECADALSEFVEWDLLEE
                     LSGDNFDRVDVVQPVLFAVMVSLAATWQAAGVQPAAVVGHSQGEIAAACVAGALTLRDA
                     ARVVALRSLAIRELSGKGGMVSVPLPEAEVRELIAAWGGRIELAAVNGPAQVVVSGEPE
                     ALEELVAQCVAQDIRARTIPVDYASHSSYVEQIEEQIAEALAGVDPQAAEVPLFSTLTG
                     EWLDANTPMDSGYWYRNLRQTVLFEHATRGLLTEGHGLFLEMSPHPVLTVPVQATIDAT
                     DSQAVTLGSLRRD"
     CDS_motif       7284..7352
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0020"
                     /evalue="8.40E-11"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="IE274_RS38730"
                     /protein_end="2449"
                     /protein_start="2426"
                     /score="33.8"
                     /tool="antismash"
                     /translation="DRVDVVQPVLFAVMVSLAATWQA"
     CDS_motif       7356..7466
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0021"
                     /evalue="9.10E-19"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="IE274_RS38730"
                     /protein_end="2487"
                     /protein_start="2450"
                     /score="59.3"
                     /tool="antismash"
                     /translation="GVQPAAVVGHSQGEIAAACVAGALTLRDAARVVALRS"
     CDS_motif       7572..7610
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0022"
                     /evalue="3.90E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE274_RS38730"
                     /protein_end="2535"
                     /protein_start="2522"
                     /score="13.7"
                     /tool="antismash"
                     /translation="AAVNGPAQVVVSG"
     CDS_motif       7680..7712
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0023"
                     /evalue="1.80E-02"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="IE274_RS38730"
                     /protein_end="2569"
                     /protein_start="2558"
                     /score="8.3"
                     /tool="antismash"
                     /translation="VDYASHSSYVE"
     CDS_motif       7821..7868
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0024"
                     /evalue="3.70E-04"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="IE274_RS38730"
                     /protein_end="2621"
                     /protein_start="2605"
                     /score="13.0"
                     /tool="antismash"
                     /translation="MDSGYWYRNLRQTVLF"
     CDS_motif       7911..7940
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0025"
                     /evalue="2.10E-02"
                     /label="PKSI-AT-mM_m9"
                     /locus_tag="IE274_RS38730"
                     /protein_end="2645"
                     /protein_start="2635"
                     /score="7.9"
                     /tool="antismash"
                     /translation="FLEMSPHPVL"
     aSDomain        9096..9632
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38730_PKS_KR.2"
                     /evalue="4.20E-58"
                     /label="IE274_RS38730_PKS_KR.2"
                     /locus_tag="IE274_RS38730"
                     /protein_end="3209"
                     /protein_start="3030"
                     /score="188.2"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: A1"
                     /tool="antismash"
                     /translation="GTALVTGGTGAIGGHVARWLAREGVEHLVLTSRRGPDAPGAAELK
                     AELEELGAKVTVAACDVADRDAVAGLLGRLVEDGHTLRSVFHAAGVGQGQPLAETTAAD
                     IAAVLEAKVAGAAHLDALLDTDELDAFVLFSSNAGVWGSGSQGAYAAANAHLDALAERR
                     RARGLTATSVAWGLWA"
     CDS_motif       9105..9197
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0026"
                     /evalue="1.30E-12"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE274_RS38730"
                     /protein_end="3064"
                     /protein_start="3033"
                     /score="40.3"
                     /tool="antismash"
                     /translation="LVTGGTGAIGGHVARWLAREGVEHLVLTSRR"
     CDS_motif       9477..9587
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38730_0027"
                     /evalue="9.20E-16"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE274_RS38730"
                     /protein_end="3194"
                     /protein_start="3157"
                     /score="50.4"
                     /tool="antismash"
                     /translation="LDAFVLFSSNAGVWGSGSQGAYAAANAHLDALAERRR"
     aSDomain        9927..10184
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38730_PKS_PP.2"
                     /evalue="2.30E-30"
                     /label="IE274_RS38730_PKS_PP.2"
                     /locus_tag="IE274_RS38730"
                     /protein_end="3393"
                     /protein_start="3307"
                     /score="96.8"
                     /tool="antismash"
                     /translation="LAPLTEPEREVILLDIVRTHAAAVLGYTGAESVDAHRAFRELGFD
                     SLTAVEVRNRLNKATGLRLPATLVFDYPTSVVLAQYLRTQL"
     aSDomain        10218..10430
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38730_PKS_Docking_Cterm.
                     1"
                     /evalue="3.20E-23"
                     /label="IE274_RS38730_PKS_Docking_Cterm.1"
                     /locus_tag="IE274_RS38730"
                     /protein_end="3475"
                     /protein_start="3404"
                     /score="74.4"
                     /tool="antismash"
                     /translation="LQELDRLEAGLSSIAPDDSARMRITMRLEALMSKWKGADAEAPAD
                     GEEVSSRLESASADEVFDFIDKELGI"
     gene            10517..>15670
                     /locus_tag="IE274_RS38735"
     CDS             10517..>15670
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (4-30). E-value:
                     1.9e-15. Score: 48.1. Matches aSDomain:
                     nrpspksdomains_IE274_RS38735_PKS_Docking_Nterm.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (35-463). E-value:
                     1e-179. Score: 589.9. Matches aSDomain:
                     nrpspksdomains_IE274_RS38735_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (569-865). E-value: 2.1e-113.
                     Score: 370.5. Matches aSDomain:
                     nrpspksdomains_IE274_RS38735_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (934-1105). E-value: 3.4e-61.
                     Score: 198.4. Matches aSDomain:
                     nrpspksdomains_IE274_RS38735_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_ER (1452-1718). E-value: 4.2e-104.
                     Score: 340.0. Matches aSDomain:
                     nrpspksdomains_IE274_RS38735_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014057313.1"
                     /locus_tag="IE274_RS38735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I polyketide synthase"
                     /protein_id="WP_190120651.1"
                     /sec_met_domain="mod_KS (E-value: 4.3e-225, bitscore:
                     734.4, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 7.5e-90, bitscore:
                     288.0, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 7.1e-115, bitscore:
                     370.5, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_N (E-value: 2.8e-11, bitscore: 30.6,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 3.1e-18, bitscore:
                     53.2, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADQQKLLDYLKRVTADLHETRQRLRDAEAEEPEPIAIVGMSCRY
                     PGDVSSPEDLWRLVAEGRDALSAFPADRGWDVEALGGRTEDGDGDPDRPERGGGFVYDA
                     GDFDAAFFGISPREAMAMDPQQRLLLESVWETFERAAIPPTSLRGSRTGVFVGATAQGY
                     GPALMASPDNVDGYLLTGDVSSVISGRVSYVFGLEGPAVTVDTACSSSLVALHLAAQAL
                     RQGECDLAVAAGVAVMVTSGAFAEFSRQGGLASDGRCKPFAEAADGTGWGEGVGVLALE
                     RLSDARRNGHQVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALAAAHLATDDIDAV
                     EGHGTGTVLGDPIEAQALLATYGQDRPADRPLLLGSVKSNIGHTQAASGVAGVIKMVMA
                     MRHGVLPENLHTDRPSTHVDWTAGAVELLDSARAWPEAGRPRRAGVSSFGVSGTNAHVI
                     VEQAPAEEPAEPEPTAAVAPPTTTPWLVSGRSAQALRAQAERIRDHVTADTTLHPVDLG
                     WSLLSGRSPLEHRAVLFGQDRDEFLSGLETVASGGDGPGVVSGAVAEGRLGVVFTGQGS
                     QRVGMGRELYETFPVFASALDEVCAHLDGQLERSLQDVMFGTDAELLEQTGYAQPALFA
                     VEVALYRLAESFGVRPEIVGGHSIGELAAAYVAGLWSLEDAAQLVAARGRLMQSLPEGG
                     AMLAVQAAEAEVLPLLAGLEDRAGVAAVNGPSQVVLSGDRTVLEGLEEKLRAEGRKVRW
                     LKVSHAFHSPLMDPILADFRKVAANLTYQDTVLPVVSNVTGRLATASELKDPDYWVRHI
                     REAVRFHDGVGALTGFGVSTLLELGPDSVLTAMADDTLSETDAQVGLIGALRKDRPEPD
                     TFLTALAKAHVRGVDVDWSPLYASQPRRRVDLPTYAFQHERYWPRPGVGGTGDVHATGL
                     SPAEHPLFGAAVALADMDGYLFTGRLSLATHPWLAGHALGGTVLLPATAFVELALHAGH
                     RVGCAHLEELTLQAPLVLPQRGGVQVQLAVGAADTFGRRPVNLYSRPQQATSDDLWSDE
                     PWQRHATGTLAPAPAARPADVDLTQWPPADAERADTDALYDSLAAAGFSYGSAFRGLRS
                     VWRRGDELFAEVALPEADQDEAAAYGLHPALLDAALHPLGLGTFVSDTEQGRMPFSWTG
                     VTLHATGAAALRVRLTAAGTDGVSLSVADASGEPVAAVDSLVLRPLAVPDAGSDQAGRH
                     DSLYRVDWSVVPAPATAPSACAVLGTDAWGLRGALERAGATVTAYPDVAELAAAVDGGA
                     AAPESVFVACAASADHTPGIAGNVRASLNDALRTVGEWLAFERGDESRLVVVTSGAVGV
                     GSGDVVSAAGLVDAPVWGLLRSAQSENPGRLALVDVDGSAAALGQLPGVLELDEPQVAV
                     RGDVVWAPRLVRAGGGALPVPAGESWQLGVTGRGTLENLALLPVADDAEVSGGRALEPR
                     EVRVSVRAAGVNFRDPLIALGMYPGDAVMGTEGAGVVVEVGSEVTDLAVGDRVLGLLEG
                     GFAPLSVADARMLARMPEGWSFAQAASVPTVFLTAYYALRDLAGLEAGESVLVHAAAGG
                     VGMAATQLARHFGAEVYGTASTGKWDVLRGLGLDDSRIASSRTLDFETSVLAGTEGRGV
                     DVVLNSLAREFVDASLRLLPRGGRFVEMGKTDLRDPATIAEDHSGVTYRSFDLIDAGHD
                     RIKEMLAEVLELFGQGVLTPL"
     aSDomain        10529..10606
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38735_PKS_Docking_Nterm.
                     1"
                     /evalue="1.90E-15"
                     /label="IE274_RS38735_PKS_Docking_Nterm.1"
                     /locus_tag="IE274_RS38735"
                     /protein_end="30"
                     /protein_start="4"
                     /score="48.1"
                     /tool="antismash"
                     /translation="QKLLDYLKRVTADLHETRQRLRDAEA"
     aSDomain        10622..11905
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38735_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="1.00E-179"
                     /label="IE274_RS38735_PKS_KS.1"
                     /locus_tag="IE274_RS38735"
                     /protein_end="463"
                     /protein_start="35"
                     /score="589.9"
                     /tool="antismash"
                     /translation="IAIVGMSCRYPGDVSSPEDLWRLVAEGRDALSAFPADRGWDVEAL
                     GGRTEDGDGDPDRPERGGGFVYDAGDFDAAFFGISPREAMAMDPQQRLLLESVWETFER
                     AAIPPTSLRGSRTGVFVGATAQGYGPALMASPDNVDGYLLTGDVSSVISGRVSYVFGLE
                     GPAVTVDTACSSSLVALHLAAQALRQGECDLAVAAGVAVMVTSGAFAEFSRQGGLASDG
                     RCKPFAEAADGTGWGEGVGVLALERLSDARRNGHQVLAVVRGSAVNQDGASNGLTAPNG
                     PSQQRVIRQALAAAHLATDDIDAVEGHGTGTVLGDPIEAQALLATYGQDRPADRPLLLG
                     SVKSNIGHTQAASGVAGVIKMVMAMRHGVLPENLHTDRPSTHVDWTAGAVELLDSARAW
                     PEAGRPRRAGVSSFGVSGTNAHVIVEQAP"
     aSModule        10622..>15670
                     /domains="nrpspksdomains_IE274_RS38735_PKS_KS.1"
                     /domains="nrpspksdomains_IE274_RS38735_PKS_AT.1"
                     /domains="nrpspksdomains_IE274_RS38735_PKS_DH.1"
                     /domains="nrpspksdomains_IE274_RS38735_PKS_ER.1"
                     /incomplete
                     /locus_tags="IE274_RS38735"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       11111..11158
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38735_0001"
                     /evalue="8.40E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE274_RS38735"
                     /protein_end="214"
                     /protein_start="198"
                     /score="20.8"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     CDS_motif       11534..11578
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38735_0002"
                     /evalue="5.40E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE274_RS38735"
                     /protein_end="354"
                     /protein_start="339"
                     /score="9.6"
                     /tool="antismash"
                     /translation="VEGHGTGTVLGDPIE"
     CDS_motif       11639..11683
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38735_0003"
                     /evalue="7.60E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE274_RS38735"
                     /protein_end="389"
                     /protein_start="374"
                     /score="11.9"
                     /tool="antismash"
                     /translation="GSVKSNIGHTQAASG"
     aSDomain        12224..13111
                     /ASF="Malonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38735_PKS_AT.1"
                     /evalue="2.10E-113"
                     /label="IE274_RS38735_PKS_AT.1"
                     /locus_tag="IE274_RS38735"
                     /protein_end="865"
                     /protein_start="569"
                     /score="370.5"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="VFTGQGSQRVGMGRELYETFPVFASALDEVCAHLDGQLERSLQDV
                     MFGTDAELLEQTGYAQPALFAVEVALYRLAESFGVRPEIVGGHSIGELAAAYVAGLWSL
                     EDAAQLVAARGRLMQSLPEGGAMLAVQAAEAEVLPLLAGLEDRAGVAAVNGPSQVVLSG
                     DRTVLEGLEEKLRAEGRKVRWLKVSHAFHSPLMDPILADFRKVAANLTYQDTVLPVVSN
                     VTGRLATASELKDPDYWVRHIREAVRFHDGVGALTGFGVSTLLELGPDSVLTAMADDTL
                     SETDAQVGLIGALRK"
     CDS_motif       12227..12274
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38735_0004"
                     /evalue="2.90E-06"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="IE274_RS38735"
                     /protein_end="586"
                     /protein_start="570"
                     /score="19.6"
                     /tool="antismash"
                     /translation="FTGQGSQRVGMGRELY"
     CDS_motif       12395..12445
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38735_0005"
                     /evalue="9.10E-04"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="IE274_RS38735"
                     /protein_end="643"
                     /protein_start="626"
                     /score="12.5"
                     /tool="antismash"
                     /translation="GYAQPALFAVEVALYRL"
     CDS_motif       12458..12580
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38735_0006"
                     /evalue="4.10E-22"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="IE274_RS38735"
                     /protein_end="688"
                     /protein_start="647"
                     /score="70.4"
                     /tool="antismash"
                     /translation="GVRPEIVGGHSIGELAAAYVAGLWSLEDAAQLVAARGRLMQ"
     CDS_motif       12674..12712
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38735_0007"
                     /evalue="1.70E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE274_RS38735"
                     /protein_end="732"
                     /protein_start="719"
                     /score="14.7"
                     /tool="antismash"
                     /translation="AAVNGPSQVVLSG"
     CDS_motif       12935..12970
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38735_0008"
                     /evalue="3.60E-05"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="IE274_RS38735"
                     /protein_end="818"
                     /protein_start="806"
                     /score="17.0"
                     /tool="antismash"
                     /translation="YWVRHIREAVRF"
     aSDomain        13319..13831
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38735_PKS_DH.1"
                     /evalue="3.40E-61"
                     /label="IE274_RS38735_PKS_DH.1"
                     /locus_tag="IE274_RS38735"
                     /protein_end="1105"
                     /protein_start="934"
                     /score="198.4"
                     /tool="antismash"
                     /translation="HPLFGAAVALADMDGYLFTGRLSLATHPWLAGHALGGTVLLPATA
                     FVELALHAGHRVGCAHLEELTLQAPLVLPQRGGVQVQLAVGAADTFGRRPVNLYSRPQQ
                     ATSDDLWSDEPWQRHATGTLAPAPAARPADVDLTQWPPADAERADTDALYDSLAAAGFS
                     YGSAFRGL"
     CDS_motif       13403..13477
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38735_0009"
                     /evalue="1.30E-08"
                     /label="PKSI-DH_m2"
                     /locus_tag="IE274_RS38735"
                     /protein_end="987"
                     /protein_start="962"
                     /score="27.3"
                     /tool="antismash"
                     /translation="WLAGHALGGTVLLPATAFVELALHA"
     aSDomain        14873..>15670
                     /ASF="ER domain putatively catalyzing 2S-configuration
                     product formation"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38735_PKS_ER.1"
                     /evalue="4.20E-104"
                     /label="IE274_RS38735_PKS_ER.1"
                     /locus_tag="IE274_RS38735"
                     /protein_end="1718"
                     /protein_start="1452"
                     /score="340.0"
                     /tool="antismash"
                     /translation="SGGRALEPREVRVSVRAAGVNFRDPLIALGMYPGDAVMGTEGAGV
                     VVEVGSEVTDLAVGDRVLGLLEGGFAPLSVADARMLARMPEGWSFAQAASVPTVFLTAY
                     YALRDLAGLEAGESVLVHAAAGGVGMAATQLARHFGAEVYGTASTGKWDVLRGLGLDDS
                     RIASSRTLDFETSVLAGTEGRGVDVVLNSLAREFVDASLRLLPRGGRFVEMGKTDLRDP
                     ATIAEDHSGVTYRSFDLIDAGHDRIKEMLAEVLELFGQGVLTPL"
     CDS_motif       14984..15022
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38735_0010"
                     /evalue="4.10E-02"
                     /label="PKSI-ER_m2"
                     /locus_tag="IE274_RS38735"
                     /protein_end="1502"
                     /protein_start="1489"
                     /score="7.2"
                     /tool="antismash"
                     /translation="MGTEGAGVVVEVG"
     CDS_motif       15149..15193
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38735_0011"
                     /evalue="3.20E-05"
                     /label="PKSI-ER_m4"
                     /locus_tag="IE274_RS38735"
                     /protein_end="1559"
                     /protein_start="1544"
                     /score="17.1"
                     /tool="antismash"
                     /translation="AASVPTVFLTAYYAL"
     CDS_motif       15218..15280
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38735_0012"
                     /evalue="2.20E-08"
                     /label="PKSI-ER_m5"
                     /locus_tag="IE274_RS38735"
                     /protein_end="1588"
                     /protein_start="1567"
                     /score="26.4"
                     /tool="antismash"
                     /translation="GESVLVHAAAGGVGMAATQLA"
     CDS_motif       15413..15451
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38735_0013"
                     /evalue="1.40E-05"
                     /label="PKSI-ER_m7"
                     /locus_tag="IE274_RS38735"
                     /protein_end="1645"
                     /protein_start="1632"
                     /score="17.3"
                     /tool="antismash"
                     /translation="TEGRGVDVVLNSL"
ORIGIN
        1 tcgtgctgtt ctcgtcggct gctggtgtgc tgggcagtgc ggggcaggcc aactatgcgg
       61 ccgctaatgc cttcttggac gcgctggctc agcaccgtcg tgcccagggt cttcctgcga
      121 cgtcgctcgc gtgggggctg tgggcggacc agggtggtat ggccggggcg ttggcggacg
      181 aggacatcga ccggatgaac cgggccggag tcgccgccct gtccgccgac gagggcctcg
      241 cgctcctcga cgcctccctc gcggagcccg acggcgccct cgtcccgatg aagctgcacc
      301 tcgacaccct gcgccgacag ttcggcgcgg acgtgccccc gctgttccgg agcctcatcc
      361 gcggcggcgg acgcacccgc cgtgtggtcg agtccgggcc cgccgcggcc gggacctcgc
      421 tcgccgacca actggtcgcg ctggcccccg agaaccgcga gcgcgccctc ctcgacctcg
      481 tccgcgcgca ggtggccgcc gtcctcggct acgcgtccgg tgacgacgtg gcgcccacca
      541 aggcgttcaa ggagctgggc ttcgactcgc tcacctctgt cgaactccgc aaccgcctca
      601 actccgcgac cgagctgcgg ctgcccgcca gcctcgtctt cgactacccg acgccgaagg
      661 tcctcgccca gtacctcggc accgagatcc tcggcgacct cgccgccgcc ccgggcgcgg
      721 ccaccggccg gagcgcgcag acggcggtcg cggcccagga cgagcccatc gccatcgtcg
      781 cgatgagctg ccgcttcccc ggcggcgtcc acacccccga agacctgtgg cggctcctca
      841 ccgacggcga agaggccatc accgagttcc cggagggccg cggctgggac acggcgtccc
      901 tctacgaccc cgaccccaac cgcgtcggca ccagctacgc ccgcgagggc ggcttcctgc
      961 acgacgcggg cgagttcgac gccgcgttct tcggcatctc cccgcgcgag gccctggcca
     1021 tggacccgca gcagcgcctg ctcctggaga cgtcctggga ggccatcgag cgcgccggaa
     1081 tcgaccccgc cacgctgcac ggcagcccca cgggcgtctt cgccggactc atctaccacg
     1141 agtacggctc ccagctcgcg agcgtccccg aggacctcgg cggctacctc ggcaccggca
     1201 gctccggtgc catcgcctcg ggccgcatct cgtactcctt cggcctggaa ggcccggcgg
     1261 tcacggtcga cacggcctgc tcgtcgtcgc tcgtcgccct gcacctggcc gcgcaggcgc
     1321 tgcggcaggg cgagtgctcg ctggccctcg cgggcggcgt gacggtcatg cccacggcgg
     1381 gcaccttcct ggagttcagc cgccagcgcg gcctggcccc cgacggccgc tgcaagccgt
     1441 tcgcggccgc cgccgacggc accagctggg gcgagggcgt gggcatgctc gtcctggagc
     1501 gcctgtccga cgcccagcgc aacggccacc aggtcctcgc agtcgtccgc ggctccgcga
     1561 tcaaccagga cggcgccagc aacggcctga ccgcccccaa cgggccgtcc cagcagcgcg
     1621 tcatcaccca ggccctcgcc aacgcccgcc tcacgaccac ggacgtcgac gccgtcgagg
     1681 cccacggcac cggcacaccc ctcggcgacc ccatcgaggc ccaggccctc atcgcgacct
     1741 acggcaagga gcgcccggcc gaccagccgc tgctcctcgg ctccgtgaag tccaacatcg
     1801 gccacaccca ggccgccgcc ggtgtcgccg gtgtcatcaa gatggtcatg gcgatgcgcc
     1861 acggcgtcct gccgcgcacc ctgaacatgg acgcgccgac ccccgaggtc gactggtcgg
     1921 cgggcaccgt ggaactcctc gcggagtccc gcgcctggcc cgagcgggac ggcggcgcgc
     1981 cgcgccgcgc gggcgtgtcg tcgttcggcg tgagcgggac gaacgcgcac gtgatcctgg
     2041 agcagggccc gtcggccgcg gcgccggagg ccgccggtgt cgcgccgtcg ccggtggtcg
     2101 cgggcgtcgt accgctggca ctctcggcga agaccgaggg cgcgctccgg gaccaggccg
     2161 cacggctgcg ggcacatctc ctggccgatg ccggtctcga actgggcgac gtcgcctggt
     2221 cgttggcggt gtcgcggtcg cggttcgagt accggggcgt cgtcctcggc ggcgaccggg
     2281 acgagctgct cgccgggctc gatcggctgg cacaggacga cgcgagcgcg cagaacgtcg
     2341 tcacggggcg cgcgctgggt ggctcggccc ggccggtgtt cgtgttcccg gggcagggct
     2401 cgcagtggac cgggatggcc cgtgaactcc tggactccag cccggtgttc gccgcccgca
     2461 tgcgggagtg cgcggacgcc ctgtccgagt tcgtggactg ggacctgatc gaagagctga
     2521 acggcgagcg gttcgaccac gtggatgtgg tccagcccgt gctgttcgcc gtgatggtgt
     2581 cgctggccga ggcctggcgc gcggcgggcg ttcagcctgc ggctgtcgtc gggcacagcc
     2641 agggtgagat cgcggccgcg tgtgtcgcgg gcgccttgtc gctgcgggac gccgcccgcg
     2701 tggtcgcgct gcgcagcctc gccatccggg agctgtccgg caagggcggc atggtgtccg
     2761 tgccgctgcc cgaggccgag gtgcgggagc tgatcaccgc gtggggcgac cgggtgtcgg
     2821 tcgcggccgt gaacggtccc gctcaggtcg tggtctccgg tgagccggac gcgctggagg
     2881 aactggtcgc gcagtgcgtg gcccgcgatg tccgcgcccg cacgatcccc gtcgactacg
     2941 cctcgcactc cgcatacgtg gagcagatcg aggcccggat agccgaggcg ctggccgggg
     3001 tggccccgca ggccgccgag gtcccgctgt actcgaccct cacaggggag tggctgggcg
     3061 ccaacacccc gatggatgcc gggtactggt accgcaacct gcgccagacc gtcctcttcg
     3121 agcacgccac ccgcggcctc ctcgccgagg ggcacgacct gttcctggag atgagccccc
     3181 acccggtgct caccgtcccc gtccaagcca ccatcgaggc cgccggacgc gagggcgcgg
     3241 cagtggccct cggctccctg cgccgcgacg acggcggcgc cgaccgtctc gccgcctccc
     3301 tcgccgaagc gcacacgcac ggcgccgagc tggactggca ggcgctcctc ccgggcgccc
     3361 gtgccaccgt cgacctgccc acgtacgcct tccagcgcca gcactactgg ctcctctcgc
     3421 cggagcagga ggcgggcgcc gagcccaccc ccgccgtgga cgaggtggag gcacgcttct
     3481 gggaggccgt ggagcgcgag gacctggcgg gcctggcggc cgagctggag gtggcggacg
     3541 gttccgccgc cgggctcggc gaggtcctgc ccgtcctgtc gtcgtggcgg cggcagcggc
     3601 gtgagaagtc caccgtggac ggctggcgct accgggtcac ctggaagtcg ctggcgagcg
     3661 gtgcgctgcc cgggccggtc ctgacgggcc gctggctggt cgtcgtaccg gaggaggctg
     3721 ccgcgcaccc gtgggtcgcg ggcgtcaccg aggcgctggc gcaggccggt gcggacgtca
     3781 ccgaagtccg tgtgagcggc gcggagctga accgggagac gctggccggg cggctgcgcg
     3841 agcagctcac ccccgacggg ccggagcccg tcggtgtggt gtccctgctg gccctcgccg
     3901 aggacccgca cccggagcag cccgtgctgc ccgccggtct cgcgggcacc gtggcgctcg
     3961 tccaggccct gggtgacgtc gaggtcgacg cgaagctgtg ggcggtctcc agcggagccg
     4021 tctccaccgg ccgcaacgac caggtggaga gccccgccca ggcgcagacc tggggcctcg
     4081 gccgcgtggt ggccctggag caccccgagc gctggggcgg cctcgtcgac ctgcccgcca
     4141 cccccgacag ccgcgccgcg gcccggttcg ccgggatcct cgcgggcgtc ggcgacgagg
     4201 accagctcgc cgtgcgcggc tccggagtct tcgtacgccg cctcgtccgc gccgagcccg
     4261 ccgcggccgc gaaggacaag accgccgcgt ccgcgcagga caagtggact ccccgcggta
     4321 ccgtcctcat caccggcggc accggcgccc tcggccccca catggcccgc tggctcgccc
     4381 gcgagggcgc cgagcacctc gtcctgacca gccgccgcgg cccggccgcg cccggcgccg
     4441 acgaactccg caccaaactc gaggagttgg gcgtccaggt caccatcgcg gcctgcgacg
     4501 tcgccgaccg cgacgccgtc gccgcactgc tcgaccagct caccgccgac ggccacactc
     4561 tgcgcgccgt catccacgcc gccgcgctca tcgagctggc gccgatcgcc accaccaccc
     4621 tcgatgagtt cgcggagatc gtcgcggcga aggtcgcggg cgccgtcgtc ctggacgagc
     4681 tcctggacgg cgcggacctc gacgcgttcg tgctgttctc gtccatcgcg ggcgtctggg
     4741 gcagcggcga ccacgccgcg tacgccgccg ccaacgcgca cctcgacgcc ctcgccgagc
     4801 accgcagggc acgcggcctg accgcgacat ccatcgcctg gggcgtgtgg aacgtcgtca
     4861 acccgtacct gagcggcagc gcgccgatcg acgtcgaccc ggagcaactg cgccgccagg
     4921 gactgccgtt cctcgacccg gacctcgcgt tcgcgggcat gcggcagacc ctcgacgacg
     4981 acgagacgtt cctggcgctc gccgacgtgg actgggacca gttcgtgccc gtgttcacct
     5041 cgcggcgcgc ccgcccgctc ctcgccgacc tgcccgacgc ccagcgcgtc ctcgcctccc
     5101 agggcggcac cgacagcgcg gaggacggcg gcgacacgcc gtccaaggcg gccgcgctgc
     5161 gggagcgcct gaccggcctc gccggacccg agcagaaccg cgtcctgctc gacctcgtcc
     5221 tcacccacgc ggccgccgtc ctcggctacg agtccgcgca ggccctcgac cccgagcggg
     5281 ccttccgcga gttcgggttc gactcgctca ccgccgtcga cctgcgcaac cgcctcggtg
     5341 ccggcaccgg cctcaagctg cccaccacgg tcgtcttcga ccaccccaac ggcaccgccc
     5401 tggccgcgta cctgcgcacc caggtcctcg gcgccgacaa ggccgccacc gccgcgcccg
     5461 tcgccaccgt cgccgcggcc accgacgagc ccatcgccat cgtcgcgatg agctgccgct
     5521 acccgggcgg catcagcagc cccgagcgca tgtgggaggt cctcgaagga cgcgccgacg
     5581 tcgtcggcgg ctaccccgcc aaccgcggct gggacatcgc ccacctctac gacccggacc
     5641 cggagacccc cggcaccacc acgaccaggg gcggcggctt cctgcacgac gcgggcgcct
     5701 tcgacccggc cttcttcggc atctcgccgc gcgaggccct ggccatggac ccgcagcagc
     5761 gcctgctcct ggagacctcc tgggaggcct tcgagcgcgc cggggtcgac ccgcgcgcgg
     5821 tgcgcggcga ggccgccgga gtgttcgtcg gcaccaacta ccaggactac ggcaccggcc
     5881 ccggccaggt gtccgcgggc tccgagggcc acatcctcac cggcagcgcg cccagcgtca
     5941 tctccggccg catcgcctac agcttcggcc tcgaaggccc ggcggtcacg gtcgacacgg
     6001 cctgctcgtc gtcgctcgtc gccatgcacc tggcggccca ggccctgcgc cagggcgagt
     6061 gctccctcgc gctcgccggc ggcgtcgccg tgatgtcgtc gcccggcgcg ctcatcgcct
     6121 tcagccagca gcgcggcctc gccgacgacg gccgctgcaa ggccttcgcc gccgcggccg
     6181 acggcatggg catggccgag ggcgtcggca tggtgctcct ggagcgcctg tccgacgccc
     6241 agcgcaacgg ccaccaggtc ctcgcggtgg tccgcggctc ggcgatcaac caggacggcg
     6301 ccagcaacgg cctgaccgcc cccaacgggc cgtcccagca gcgcgtcatc cgccaggccc
     6361 tcgccaacgc ccggctcacc cccgccgacg tcgacgcggt cgaggcccac ggcaccggca
     6421 ccacgctcgg cgacccgatc gaggcgcagg ccctcctcgc cacctacggc caggagcgcc
     6481 cggacagcgg cgaacccctg tggctgggct ccatcaagtc caacatcggc cacagtcagg
     6541 ccgcctccgg cgtcgcgggc gtcatgaaga tggtcctcgc catgcaccac ggcgtgctgc
     6601 cccagacgct ccacgtcgac gagccgactc ccgaggtcga ctggaccgaa ggcgccgtcg
     6661 cgctcctgac cgaggcccgc gactggcccg agcggggcga cgcgccccgc cgcgcgggcg
     6721 tctcctcctt cggcatgagc ggtacgaacg cccacgtcat cctggaacag ctcccggccg
     6781 ccgaacagcc gcagcccgtc ggggccgaca gcgacgacgg tgctgccgtg ccgtcgccgg
     6841 tggtggccgg ggtcgtaccg ctggccctct cggcgaagtc cgagggcgcg ctgcgggacc
     6901 aggccgcgcg cctccgggaa cacctcgtca cccggggcag cctcgaactg gacgatgtgg
     6961 cctggtcgtt ggcggtgtca cggtcgcggt tcgagcatcg gggcgtcgtc ctcgggcggg
     7021 accgggacga actgctcgcc gggctcgacg cgctcactca ggaggacgcg gccgccacgc
     7081 aggtggtgtc cggacgggcg ctgggcggca tcgtccggcc ggtgttcgtg ttcccggggc
     7141 aggggtcgca gtgggccggg atggcgcgtg agctgctcga ctccagtccg gtgttcgccg
     7201 atcggatgcg ggagtgcgcg gacgcgctgt cggagttcgt ggagtgggac ctgcttgagg
     7261 agctgagtgg ggacaacttc gaccgggtgg atgtggtgca gccggtcctg ttcgccgtga
     7321 tggtgtcgct ggccgcgacc tggcaggcgg cgggagttca gcctgccgcc gtggtcgggc
     7381 acagtcaggg cgagatcgcc gccgcctgcg tcgcgggcgc gctgaccttg cgggacgcgg
     7441 cccgtgtcgt ggcgctgcgg agcctggcga tccgggagct gtcgggcaag ggcgggatgg
     7501 tgtccgtgcc gctgcccgag gccgaggtgc gggaactgat cgctgcctgg ggcggccgga
     7561 tcgagctggc cgccgtcaac ggtccggccc aggtcgtcgt ctccggtgag cccgaggcgc
     7621 tggaagaact ggtcgcccag tgtgtcgccc aggacatccg cgcccggacg atcccggtgg
     7681 actacgcctc gcactcctcg tatgtggagc agatcgagga gcagatcgct gaggcgctgg
     7741 ccggggtgga cccgcaggcg gccgaggtgc ccctgttctc gacgctgacg ggggagtggc
     7801 tggacgccaa caccccgatg gattcgggct attggtaccg caacctccgt cagacggtcc
     7861 tcttcgagca cgccacccgc ggcctcctga ccgaggggca cgggctgttc ctggagatga
     7921 gcccgcaccc ggtcctgacc gtcccggtgc aggccaccat cgacgcgacc gacagccagg
     7981 ccgtcaccct cggctccctc cgccgcgacg acggcggcgc caaccggctg ctcgcctcga
     8041 tcgccgaagc gcacgcccac ggcgccgagt tggactgggc agccctctac ccgggcgccc
     8101 gtgccaccgt cgacctgccc acgtacgcct tccagcgcga ccactactgg ctgctcgccc
     8161 cgcaggagga ggagcagccg gagggtgcgc cgctcgccac cgacgaggtg gagtcgcggt
     8221 tctgggacgc cgtggaacgc gaggacctgg aaggcctcgc ggccgagctg gacgtcgcgg
     8281 acggtccggc cgccgagctc ggcgcggtcc tgccggtcct ctcgtcctgg cggcgccagc
     8341 ggcgcgagcg ggcgaccctc gacagctggc gctaccaggt cgcctgggag cccctcgcgg
     8401 gcgagcttcc ggccgccggt ccgacgggcc gctggctggt cgtcgtaccg gaggagccgc
     8461 agcggcaggg cgcgccggag caggccgacg ggtcgcaggc gtggcgtgcc gccgtcatcg
     8521 aggccctggc gcagtccggc gcccaggtgc acgaactccg cgtccccgca ggtgagatga
     8581 cgcgcgaggc gctggccgag cggctgcgtg aactggccgc cgccgacccg gcggaaccga
     8641 ccggcgtgct ctccctgctc gccctcgacg agtccgccct cgacgagtcc gccaccggcg
     8701 cgggtgcccg tgccgaccag ccgggtgtcc ccgccgctct cggcggcacc ttcaccctcg
     8761 tccaggccct cggcgacgcc ggaatcgggg cgcggctgtg ggccgtcacc cggggcgccg
     8821 tcgccaccgg ccccgccgac cccgccgccc tgcccgcgca ggcgcaggtg tggggcctcg
     8881 gccgggtcgc ggccctggag tgccccgacc gctggggcgg cctcgtcgac gtaccgcagg
     8941 accccgacaa gcgggccgtg tcgcagctcg tcgggatcct cgcgggcgcc ggggacgagg
     9001 accagctcgc ggtgcggcag gcgggtgtgc tcgtgcggcg gttcgtgcgg gcgccgctcg
     9061 gtgcgggcga ggcgcgggag tggtcgccgc gcggtacggc actcgtcacc ggcggtacgg
     9121 gtgcgatcgg cgggcatgtg gcgcgctggc tcgcccgcga gggcgtcgag cacctcgtcc
     9181 tcaccagccg tcgcggcccg gacgcccccg gcgccgccga actcaaggcg gaactggagg
     9241 agttgggcgc caaggtgacc gtcgcggcct gcgacgtggc cgaccgtgac gccgtcgccg
     9301 ggctcctcgg gcgactcgtc gaggacgggc acacgctgcg ctccgtgttc cacgcggcgg
     9361 gcgtcggcca gggccagccc ctcgccgaga cgacggccgc cgacatcgcc gccgtcctgg
     9421 aggcgaaggt cgcgggcgcc gcgcacctcg acgcgctcct cgacaccgac gagctggacg
     9481 cgttcgtgct cttctcgtcc aacgcgggcg tgtggggcag cggcagccag ggcgcgtacg
     9541 ccgccgcgaa cgcgcacctc gacgcgctcg ccgagcggcg ccgggcccgc ggcctgaccg
     9601 ccacctcggt ggcgtggggc ctgtgggccg ggggcggcat ggccggggac gacggcgagg
     9661 agcagttccg ccgtcgcggc ctgcggccga tggcaccgga cctcgcggtc gccgcgctcg
     9721 cccaggcggt ggcgcacgac gagacgttcg tggccgtcgc cgacctggac tgggagcggt
     9781 tcgcgcccgc cttcacgtcg gcgcggacca gcccgttcat cggtgacctg cccgaggtcc
     9841 gccggtacgc gcggtccgtg gccgccgagc cggcggccga cgcgggcacc ggcgacgacg
     9901 cggcggccgg cctgcggcgc cgcctggccc cgctcaccga gcccgagcgc gaggtgatcc
     9961 tgctcgacat cgtgcgcacc cacgcggccg ccgtgctcgg ctacaccgga gcggagtccg
    10021 tcgacgccca ccgcgccttc cgggagctcg gcttcgactc cctgacggcc gtggaggtcc
    10081 gcaaccgcct caacaaggcc acggggctcc ggctgcccgc caccctcgtg ttcgactacc
    10141 cgacgtccgt cgtcctggcc cagtacctgc ggacgcagtt gctccaggac gacgccgccg
    10201 gggtggactc cacgctccag gagctggacc gcctggaggc gggcctcagc tccatcgcgc
    10261 ccgacgacag cgcccgcatg cgcatcacga tgcgcctgga ggcactgatg tcgaagtgga
    10321 agggcgcgga cgccgaggcg ccggccgacg gcgaggaggt ctcctcgcgg ctcgagtcgg
    10381 cgtccgccga tgaggtcttc gacttcatcg acaaagaact cggcatttcc tgactcagtc
    10441 cgaccgggcc ggtgcacggc ccggtcggcc cgaccggtgc ggtttttctg tgactacgcg
    10501 aacaggtgag tttccgatgg cggaccagca aaagctcctc gactacctca agcgggtgac
    10561 cgccgacctc cacgagacgc gccagcggct gcgcgacgcc gaggcggagg agcccgagcc
    10621 catcgccatc gtcggaatga gctgccgcta ccccggcgac gtgagcagcc cggaggacct
    10681 gtggcggctc gtggccgagg gccgcgacgc gctctccgcc ttccccgccg accgcggctg
    10741 ggacgtcgaa gcgctcggcg gtcgcacgga ggacggcgac ggcgacccgg accggcccga
    10801 gcgcggcggc ggcttcgtct acgacgccgg tgacttcgac gccgccttct tcgggatctc
    10861 gccccgcgag gccatggcca tggaccccca gcagcgcctc ctcctggagt ccgtctggga
    10921 gaccttcgag cgggccgcca tcccgccgac ctccctgcgc ggcagccgca ccggcgtgtt
    10981 cgtcggcgcc accgcgcagg gctacggccc cgccctgatg gcgtcgcccg acaacgtcga
    11041 cggctacctc ctcaccggtg acgtctccag cgtcatctcc ggccgcgtgt cgtacgtctt
    11101 cggcctcgaa ggcccggccg tcaccgtcga caccgcctgc tcgtcgtccc tcgtcgccct
    11161 gcacctggcc gcgcaggcac tgcggcaggg cgagtgcgac ctcgccgtcg ccgccggtgt
    11221 cgccgtcatg gtcacctccg gcgcgttcgc ggagttcagc cgccagggcg gcctcgcctc
    11281 cgacggccgc tgcaagccgt tcgccgaggc cgcggacggc accggctggg gcgagggcgt
    11341 cggcgtcctg gccctggaac gcctctcgga cgcccgccgc aacggccacc aggtcctcgc
    11401 cgtcgtccgt ggctccgccg tgaaccagga cggtgcgagc aacggcctga ccgcccccaa
    11461 cggcccctcc cagcagcgcg tcatccgcca ggccctcgcc gccgcccacc tcgccaccga
    11521 cgacatcgac gccgtcgagg gccacggcac cggcacggtc ctcggcgacc ccatcgaggc
    11581 ccaggccctg ctcgccacct acggccagga ccgccccgcc gaccgcccgc tgctcctcgg
    11641 ctccgtgaag tccaacatcg gccacaccca ggccgcttcg ggcgtcgccg gagtcatcaa
    11701 gatggtcatg gcgatgcggc acggcgtcct gcccgagaac ctgcacaccg accgccccag
    11761 cacccacgtc gactggacgg cgggcgccgt cgaactcctc gactcggccc gcgcctggcc
    11821 cgaggccggg cgcccccgcc gcgcgggcgt ctcctccttc ggcgtgagcg gcaccaacgc
    11881 ccacgtcatc gtcgagcagg cccccgccga ggagcccgcc gagccggagc cgacggcggc
    11941 cgtggcaccc ccgaccacca ccccgtggct ggtgtcgggc cgcagcgccc aggccctgcg
    12001 cgcccaggcc gagcgcatcc gcgaccacgt caccgccgac accaccctcc accccgtcga
    12061 cctgggctgg tccctcctgt cgggccgctc accgctggaa caccgcgccg tgctcttcgg
    12121 ccaggaccgg gacgagttcc tgtccggcct ggaaacggtc gcctccgggg gcgacggtcc
    12181 gggtgtggtg tcgggtgcgg tggccgaggg ccgtctcggg gtcgtgttca cgggccaggg
    12241 cagtcagcgg gtcggtatgg gccgggagtt gtacgagacg ttcccggtgt tcgcctcggc
    12301 gctggacgag gtgtgtgcgc atctggatgg gcagctagaa cgttcgctcc aggacgtgat
    12361 gtttggtacg gatgccgagc tgttggagca gacggggtat gcgcagcccg cactgttcgc
    12421 cgtcgaggtg gccctgtacc gccttgccga gtccttcggc gtacggcccg agatcgtcgg
    12481 tgggcactcg atcggtgagc tggccgccgc gtatgtggcc gggctgtggt ccttggagga
    12541 tgcggcccaa ctggtcgccg cgcgcggccg gttgatgcag tcgctgcccg agggcggggc
    12601 gatgctcgcg gtgcaggcgg ccgaggcgga ggtactgccg ctgctcgccg gtctggagga
    12661 ccgggccggt gtggccgccg tcaacggccc gtcgcaggtg gtgctctccg gtgaccgcac
    12721 ggtcctggag ggcctggagg agaagcttcg cgccgagggc cgtaaggtcc gctggctgaa
    12781 ggtctcccac gccttccact cgcccctgat ggacccgatc cttgcggact tccgcaaggt
    12841 cgccgcgaac ctgacctacc aggacaccgt cctcccggtc gtctccaacg tcaccgggcg
    12901 cctcgccacc gcgagcgagc tgaaggaccc cgactactgg gtccgccaca tccgcgaggc
    12961 cgtccgcttc cacgacggag tcggcgcgct caccggcttc ggtgtgtcga ccctgctgga
    13021 gctgggcccc gactccgtcc tcacggcgat ggcggacgac accctcagcg agacggacgc
    13081 ccaggtcggc ctcatcggcg ccctccgcaa ggaccgcccc gagccggaca cgttcctgac
    13141 cgccctcgcc aaggcccacg tgcgcggagt cgacgtcgac tggtccccgc tgtacgcgtc
    13201 ccagccgcgc cgccgcgtcg atctgcccac gtacgccttc cagcacgagc gctactggcc
    13261 gcgtcccggc gtcggcggca ccggtgacgt gcacgcgacc gggctgagcc cggcggagca
    13321 cccgctgttc ggcgccgccg tcgcgctcgc cgacatggac ggctacctct tcacgggcag
    13381 actctccctc gcgacccacc cgtggctcgc gggccacgcc ctcggcggca cggtcctgct
    13441 gcccgccacg gccttcgtcg agctggccct gcacgccgga caccgcgtcg gctgcgcgca
    13501 cctggaggag ctgaccctcc aggcacccct cgtcctgccg cagcgcggcg gcgtacaggt
    13561 gcagctcgcc gtgggcgccg ccgacacctt cggccgccgc ccggtgaacc tctactcgcg
    13621 cccccagcag gcgacctcgg acgacctgtg gtccgacgag ccctggcagc gccacgccac
    13681 cggaaccctc gcccccgccc cggccgcccg ccccgccgac gtcgacctca cccagtggcc
    13741 cccggccgac gccgagcggg ccgacaccga cgcgctgtac gacagcctcg ccgccgccgg
    13801 attcagctac gggtcggcgt tccggggcct gcggtcggtg tggcggcgcg gcgacgaact
    13861 cttcgccgag gtcgcgctgc ccgaggccga ccaggacgag gccgccgcgt acggactgca
    13921 cccggcgctc ctcgacgccg ccctgcaccc gctgggcctc ggcaccttcg tgtccgacac
    13981 cgagcagggc cgcatgccct tctcctggac cggcgtgacc ctgcacgcga ccggcgcggc
    14041 cgcgctgcgc gtgcgcctca ctgccgccgg gaccgacggc gtgtccctct ccgtcgccga
    14101 tgcctccggc gagccggtgg ccgccgtcga ctccctcgtc ctgcggcccc tcgcggtgcc
    14161 ggacgcgggt tccgaccagg ccggtcgcca cgactcgctg taccgcgtgg actggagcgt
    14221 ggtgcccgcg cccgccaccg cgccgagcgc ctgcgccgtc ctgggcacgg acgcgtgggg
    14281 gctgcgcggg gcgctggagc gtgccggtgc gacggtgacg gcgtacccgg acgtggccga
    14341 gctggccgcc gctgtcgacg gcggcgccgc tgccccggag tccgtcttcg tcgcctgtgc
    14401 cgcgtccgcc gaccacacgc cgggcatcgc cggaaacgtg cgcgcttccc tcaacgacgc
    14461 cctgcgcacc gtgggggagt ggctggcctt cgagcgcggc gacgagtcgc gtctggtcgt
    14521 ggtgacctcc ggtgccgtgg gcgtgggctc cggtgacgtc gtgtcggccg cgggcctggt
    14581 ggacgccccg gtgtggggcc tgctgcggtc ggcgcagtcg gagaacccgg gccgtctcgc
    14641 cctggtggac gtcgacggct cggcggcggc gcttgggcag ctgcccggcg tcctcgaact
    14701 ggacgagccg caggtggcgg tgcgcgggga cgtggtgtgg gcgccgcgcc tcgtgcgggc
    14761 cggcgggggc gcgctgccgg tcccggcggg cgagtcctgg cagttggggg tcacgggccg
    14821 gggcacgctg gagaacctgg cgctgcttcc cgtcgccgac gacgccgagg tgtccggcgg
    14881 ccgggcgttg gaaccgcgcg aggtacgggt ctccgtgcgc gccgcggggg tcaacttccg
    14941 tgacccgctg atcgccctgg gcatgtaccc cggcgacgcg gtgatgggca ccgaaggcgc
    15001 cggtgtcgtc gtcgaggtcg gctccgaggt gacggatctg gccgtcggcg accgggtcct
    15061 cggtctcctc gagggcggct tcgcgcccct gtccgtcgcg gacgcgcgga tgctggcccg
    15121 gatgccggag ggctggtcgt tcgcgcaggc ggcgtcggtg ccgacggtgt tcctcacggc
    15181 gtactacgcg ctgcgggacc tcgccggtct cgaagccggt gagtcggtcc tggtgcacgc
    15241 cgccgccggt ggtgtgggca tggccgcgac gcagctcgcc cggcacttcg gtgccgaggt
    15301 gtacggcacg gccagcaccg gcaagtggga cgtgctgcgg ggcctcggcc tcgacgactc
    15361 gcgtatcgcc tcatcccgca cgctggactt cgagacgtcg gtgctggcag ggaccgaggg
    15421 ccggggcgtc gacgtcgtac tgaactccct ggcgcgggag ttcgtggacg cctcgctgcg
    15481 gctgctgccg cgtggcgggc ggttcgtgga gatgggcaag accgacctcc gcgacccggc
    15541 caccatcgcc gaggaccact ccggcgtcac ctaccggagc ttcgacctga tcgacgccgg
    15601 acacgaccgc atcaaggaga tgctggcgga ggtcctggag ctgttcgggc agggggtgtt
    15661 gacgccgctg
//
