LOCUS       NZ_BMVR01000034        16242 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces flavofungini strain JCM 4753 sequence34, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVR01000034
VERSION     NZ_BMVR01000034.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces flavofungini
  ORGANISM  Streptomyces flavofungini
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 16242)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650815.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:46:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,873
            CDSs (total)                      :: 7,799
            Genes (coding)                    :: 7,638
            CDSs (with protein)               :: 7,638
            Genes (RNA)                       :: 74
            rRNAs                             :: 1, 1, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 161
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 161
            Pseudo Genes (frameshifted)       :: 43 of 161
            Pseudo Genes (incomplete)         :: 137 of 161
            Pseudo Genes (internal stop)      :: 10 of 161
            Pseudo Genes (multiple problems)  :: 26 of 161
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:42:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 16242
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVR01000034.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     gene            <1..7268
                     /locus_tag="IE274_RS38605"
                     /old_locus_tag="GCM10010349_78840"
     source          1..16242
                     /culture_collection="JCM:4753"
                     /db_xref="taxon:68200"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces flavofungini"
                     /strain="JCM 4753"
                     /submitter_seqid="sequence34"
                     /type_material="type strain of Streptomyces flavofungini"
     region          1..16242
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..16242
                     /SMILES="C(C)=CC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..16242
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[<4:7268](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      <5..7268
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     CDS_motif       <7..104
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38605_0001"
                     /evalue="8.60E-20"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE274_RS38605"
                     /protein_end="33"
                     /protein_start="0"
                     /score="63.3"
                     /tool="antismash"
                     /translation="VLFSSAAGVLGSAGQANYAAANAFLDALAQHRR"
     CDS             <5..7268
                     /NRPS_PKS="Domain: PKS_PP (145-231). E-value: 1.2e-31.
                     Score: 100.9. Matches aSDomain:
                     nrpspksdomains_IE274_RS38605_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (258-689). E-value:
                     4e-174. Score: 571.4. Matches aSDomain:
                     nrpspksdomains_IE274_RS38605_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (806-1101). E-value: 9.3e-108.
                     Score: 352.0. Matches aSDomain:
                     nrpspksdomains_IE274_RS38605_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (1168-1334). E-value: 1.3e-67.
                     Score: 219.3. Matches aSDomain:
                     nrpspksdomains_IE274_RS38605_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (1723-1903). E-value: 7.1e-61.
                     Score: 197.3. Matches aSDomain:
                     nrpspksdomains_IE274_RS38605_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1997-2082). E-value: 1.6e-29.
                     Score: 94.1. Matches aSDomain:
                     nrpspksdomains_IE274_RS38605_PKS_PP.2"
                     /NRPS_PKS="Domain: Thioesterase (2201-2418). E-value:
                     1.1e-32. Score: 106.2. Matches aSDomain:
                     nrpspksdomains_IE274_RS38605_Thioesterase.1"
                     /codon_start=3
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014060783.1"
                     /locus_tag="IE274_RS38605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_78840"
                     /product="type I polyketide synthase"
                     /protein_id="WP_190120625.1"
                     /sec_met_domain="PP-binding (E-value: 1.4e-15, bitscore:
                     47.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 3.6e-219, bitscore:
                     717.0, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 3.7e-88, bitscore:
                     284.5, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.4e-108, bitscore:
                     352.0, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 4.7e-66, bitscore:
                     211.3, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 1.8e-24, bitscore:
                     76.4, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLFSSAAGVLGSAGQANYAAANAFLDALAQHRRAQGLPATSLAWG
                     LWADQGGMAGALADEDIDRMNRAGVAALSADEGLALLDASLAEPDGALVPMKLDTDILR
                     QQFGADVPPLFRSLIRAQVRKAVTAQAGGAAANGQEPLADRLAGLDAADREQFLVDLVR
                     ANVAAVLGYPSPESVDAAKAFKELGFDSLTSVELRNRLNGATALRLPASLVFDYPTPVA
                     LAAHLRTELLGSLPETAAPSATKGRKDTPRDAADEPIAIVAMSCRYPGGVRSPEDLWRM
                     VAAGADGLTGFPVNRGWDVTAPAGLDGPGADGDDGLTYVTTGAFLHEADEFDPDFFGIN
                     HREALAMDPQQRLLLETSWEAVERAGIVPSTVRASDTGVFVGLSTQGYSTTLNGAEGVE
                     GYVMTGDAASVASGRLSYSFGFEGPAVTVDTACSSSLVALHLAVQALRQGECAMALAGG
                     AAVMPTPTSFAEFSRQRGLAPDGRCKSFAAAADGTGWGEGVGMLVLERLSDAQRNGHQV
                     LAVVRGSAINQDGASNGLTAPNGPSQQRVIRQALANARLTPADVDAVEAHGTGTTLGDP
                     IEAQALIATYGKDHTDDRPLWLGSLKSNIAHTQAAAGVGGVIKTVMAMRHGTLPKTLYV
                     DAPTPEVDWSGAGVELLTEARDWPGREDGAPRRAGVSSFGISGTNAHVILEQAPEEAAE
                     AAGSTATAGSTAAPALSGPPVIPLALSAKTPESLPGQAARLREHLLAHPDLELGDVAWS
                     LAVARQRFEHRGVVVGADRDELLAGLAELAQGDTAARNVVVGRTLGGTVRPVFVFPGQG
                     SQWAGMARELLDSSPVFAERMRECGDALSEFVDWNLFDELSGERFDRVDVVQPVLFAVM
                     VSLAATWQAAGVEPAAVVGHSQGEIAAACVAGVLGLRDAARVVALRSQAIRELSGKGGM
                     VSLVLPQDETRTLLEAWDGRIEIAAVNGPSQVVVSGDPEALEELIAECAARELRARAIP
                     VDYASHSSYVEQIEARIDEALAEVAPSAARTPLYSTLTGAWLDADTPMDAGYWYRNLRH
                     TVLFEQATRALLTEGHGLFLEMSPHPVLTVPVQETIDATAPTGAVALGSLRRDEGGPDQ
                     LYAALAAAHVHGAELDWRALLPGERAVVDLPTYAFQRQRFWPAPAAAGTGDVTAVGIES
                     AGHPLLGASVELADADQYLLTGRLTRRTHPWLADHAVGDTVLLPGTAYVEMALRAGDEV
                     GCGLVEELTLQAPLVVAEDDTVTLQVWVGAPDTAGRRPLTVSSRTQGATDTPWTRHATG
                     TLADTSGAPAQEDGALAVWPPAGAEAVAVDGFYERLAEGGLAYGPAFQGLRAAWRDPAG
                     DAVYAEVHLPEDAHRDARAFGVHPALLDAALHAVALAPFAEADGVRLPFAWSGVTLAAQ
                     GATVLRVRVRPDGTGGVALLFADDNGAPVARADSLELRPVAPGQLRAASGGGHRDALFH
                     VEWTPLPAATPADVAGTTWATVGPDPLTAGAELTASGAQMAAYEDIDALYAALDDGADA
                     PDTLLVSFTDGPGAEGPDGTADSLDAVATAERARAALGRALALLQTWQADARLSATRLV
                     LVTRGAVAADGGDVPDLAHAPLWGLARSAQSEQAGGPDGAGCVLFDLDAAYGVDGAGSP
                     AAEGDADAEGTPARPADQSAAALLIAGLALDEPQLAVREGVLLAPRLVPATAPATTPAV
                     DGGADTTEAGAPEGTAPTAPRTPDPHGTVLITGATGTLGALVARHLVTEHGARRLLLTG
                     RRGPDAPGAAELVAELEGLGAEARVVACDVADREALAGVLAAIPAAHPLTAVVHTAGVL
                     DDALVGSLTPARLDTVLRPKLDAALNLAELTANQDLAEFVLFSSAAATFGSPGQGNYAA
                     ANAFLDAFAHHLRARGIPATALAWGLWAESSEMTGHLDEARRTRISRGGVLPLSSREGV
                     ELFDTARSSGAPLLLPVRLDTAALRAGARQGEAVPPLLRRLVRAQARRAAAGAAASEAE
                     AFARRLAAASADERANLLIALVRDQAAAVLGHASADRVEDERGFLELGFDSLTGVELRN
                     RLMTATGLRLPATLVFQNRTPRALADRLAADLDQAVPAGQDPATPRERTAGQPQHTRTA
                     PAARQPAAASTATADAHRAEAVPRPVAAPRPATGLAELYDEAARQGRADDLIPLLRTMA
                     QFRASFTGEGELDVPRAPFTLARGEEPVGVVLFTSYVGRSSAYDYARFGAYFRDRRDVS
                     VITHPGFLEGELLPADKEALVRLHADTVQRHTGGKPYVLAGHSSGGLVAHAVARELEER
                     GAGPAGVVLVDTYVEEKALGDMAAAMGKQLSDRYDSAPDAEGAAVDADGDDWGDAWVTA
                     MARYMFLGLLPDAIQAPTLLVRASEPLMEWTQEYDWRPSWKLEHTAVDVPGTHFTVMEE
                     HSATTARAVEAWLDRL"
     misc_feature    20..36
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.42"
                     /tool="antismash"
     aSDomain        441..698
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38605_PKS_PP.1"
                     /evalue="1.20E-31"
                     /label="IE274_RS38605_PKS_PP.1"
                     /locus_tag="IE274_RS38605"
                     /protein_end="231"
                     /protein_start="145"
                     /score="100.9"
                     /tool="antismash"
                     /translation="LAGLDAADREQFLVDLVRANVAAVLGYPSPESVDAAKAFKELGFD
                     SLTSVELRNRLNGATALRLPASLVFDYPTPVALAAHLRTEL"
     aSDomain        780..2072
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38605_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="4.00E-174"
                     /label="IE274_RS38605_PKS_KS.1"
                     /locus_tag="IE274_RS38605"
                     /protein_end="689"
                     /protein_start="258"
                     /score="571.4"
                     /tool="antismash"
                     /translation="IAIVAMSCRYPGGVRSPEDLWRMVAAGADGLTGFPVNRGWDVTAP
                     AGLDGPGADGDDGLTYVTTGAFLHEADEFDPDFFGINHREALAMDPQQRLLLETSWEAV
                     ERAGIVPSTVRASDTGVFVGLSTQGYSTTLNGAEGVEGYVMTGDAASVASGRLSYSFGF
                     EGPAVTVDTACSSSLVALHLAVQALRQGECAMALAGGAAVMPTPTSFAEFSRQRGLAPD
                     GRCKSFAAAADGTGWGEGVGMLVLERLSDAQRNGHQVLAVVRGSAINQDGASNGLTAPN
                     GPSQQRVIRQALANARLTPADVDAVEAHGTGTTLGDPIEAQALIATYGKDHTDDRPLWL
                     GSLKSNIAHTQAAAGVGGVIKTVMAMRHGTLPKTLYVDAPTPEVDWSGAGVELLTEARD
                     WPGREDGAPRRAGVSSFGISGTNAHVILEQAP"
     aSModule        780..7259
                     /complete
                     /domains="nrpspksdomains_IE274_RS38605_PKS_KS.1"
                     /domains="nrpspksdomains_IE274_RS38605_PKS_AT.1"
                     /domains="nrpspksdomains_IE274_RS38605_PKS_DH.1"
                     /domains="nrpspksdomains_IE274_RS38605_PKS_KR.1"
                     /domains="nrpspksdomains_IE274_RS38605_PKS_PP.2"
                     /domains="nrpspksdomains_IE274_RS38605_Thioesterase.1"
                     /final_module
                     /locus_tags="IE274_RS38605"
                     /monomer_pairings="mmal -> Me-ccmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       1272..1319
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38605_0002"
                     /evalue="1.30E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE274_RS38605"
                     /protein_end="438"
                     /protein_start="422"
                     /score="20.3"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     CDS_motif       1695..1739
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38605_0003"
                     /evalue="7.10E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE274_RS38605"
                     /protein_end="578"
                     /protein_start="563"
                     /score="11.9"
                     /tool="antismash"
                     /translation="VEAHGTGTTLGDPIE"
     CDS_motif       2418..2474
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38605_0004"
                     /evalue="3.10E-10"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE274_RS38605"
                     /protein_end="823"
                     /protein_start="804"
                     /score="31.5"
                     /tool="antismash"
                     /translation="VFVFPGQGSQWAGMARELL"
     aSDomain        2424..3308
                     /ASF="Methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38605_PKS_AT.1"
                     /evalue="9.30E-108"
                     /label="IE274_RS38605_PKS_AT.1"
                     /locus_tag="IE274_RS38605"
                     /protein_end="1101"
                     /protein_start="806"
                     /score="352.0"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGSQWAGMARELLDSSPVFAERMRECGDALSEFVDWNLFDE
                     LSGERFDRVDVVQPVLFAVMVSLAATWQAAGVEPAAVVGHSQGEIAAACVAGVLGLRDA
                     ARVVALRSQAIRELSGKGGMVSLVLPQDETRTLLEAWDGRIEIAAVNGPSQVVVSGDPE
                     ALEELIAECAARELRARAIPVDYASHSSYVEQIEARIDEALAEVAPSAARTPLYSTLTG
                     AWLDADTPMDAGYWYRNLRHTVLFEQATRALLTEGHGLFLEMSPHPVLTVPVQETIDAT
                     APTGAVALGSLRRD"
     CDS_motif       2577..2645
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38605_0005"
                     /evalue="5.60E-11"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="IE274_RS38605"
                     /protein_end="880"
                     /protein_start="857"
                     /score="34.3"
                     /tool="antismash"
                     /translation="DRVDVVQPVLFAVMVSLAATWQA"
     CDS_motif       2649..2759
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38605_0006"
                     /evalue="2.10E-18"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="IE274_RS38605"
                     /protein_end="918"
                     /protein_start="881"
                     /score="58.1"
                     /tool="antismash"
                     /translation="GVEPAAVVGHSQGEIAAACVAGVLGLRDAARVVALRS"
     CDS_motif       2865..2903
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38605_0007"
                     /evalue="1.60E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE274_RS38605"
                     /protein_end="966"
                     /protein_start="953"
                     /score="14.9"
                     /tool="antismash"
                     /translation="AAVNGPSQVVVSG"
     CDS_motif       3114..3161
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38605_0008"
                     /evalue="5.50E-05"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="IE274_RS38605"
                     /protein_end="1052"
                     /protein_start="1036"
                     /score="15.3"
                     /tool="antismash"
                     /translation="MDAGYWYRNLRHTVLF"
     aSDomain        3510..4007
                     /ASF="catalytic triad H,G,P found: False"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38605_PKS_DH.1"
                     /evalue="1.30E-67"
                     /label="IE274_RS38605_PKS_DH.1"
                     /locus_tag="IE274_RS38605"
                     /protein_end="1334"
                     /protein_start="1168"
                     /score="219.3"
                     /tool="antismash"
                     /translation="HPLLGASVELADADQYLLTGRLTRRTHPWLADHAVGDTVLLPGTA
                     YVEMALRAGDEVGCGLVEELTLQAPLVVAEDDTVTLQVWVGAPDTAGRRPLTVSSRTQG
                     ATDTPWTRHATGTLADTSGAPAQEDGALAVWPPAGAEAVAVDGFYERLAEGGLAYGPAF
                     QGL"
     CDS_motif       3555..3608
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38605_0009"
                     /evalue="3.90E+01"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE274_RS38605"
                     /protein_end="1201"
                     /protein_start="1183"
                     /score="-2.9"
                     /tool="antismash"
                     /translation="YLLTGRLTRRTHPWLADH"
     CDS_motif       3594..3668
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38605_0010"
                     /evalue="3.10E-12"
                     /label="PKSI-DH_m2"
                     /locus_tag="IE274_RS38605"
                     /protein_end="1221"
                     /protein_start="1196"
                     /score="38.8"
                     /tool="antismash"
                     /translation="WLADHAVGDTVLLPGTAYVEMALRA"
     aSDomain        5175..5714
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38605_PKS_KR.1"
                     /evalue="7.10E-61"
                     /label="IE274_RS38605_PKS_KR.1"
                     /locus_tag="IE274_RS38605"
                     /protein_end="1903"
                     /protein_start="1723"
                     /score="197.3"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GTVLITGATGTLGALVARHLVTEHGARRLLLTGRRGPDAPGAAEL
                     VAELEGLGAEARVVACDVADREALAGVLAAIPAAHPLTAVVHTAGVLDDALVGSLTPAR
                     LDTVLRPKLDAALNLAELTANQDLAEFVLFSSAAATFGSPGQGNYAAANAFLDAFAHHL
                     RARGIPATALAWGLWAE"
     CDS_motif       5178..5279
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38605_0011"
                     /evalue="4.60E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE274_RS38605"
                     /protein_end="1758"
                     /protein_start="1724"
                     /score="28.9"
                     /tool="antismash"
                     /translation="TVLITGATGTLGALVARHLVTEHGARRLLLTGRR"
     CDS_motif       5565..5666
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38605_0012"
                     /evalue="9.40E-21"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE274_RS38605"
                     /protein_end="1887"
                     /protein_start="1853"
                     /score="66.4"
                     /tool="antismash"
                     /translation="FVLFSSAAATFGSPGQGNYAAANAFLDAFAHHLR"
     aSDomain        5997..6251
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38605_PKS_PP.2"
                     /evalue="1.60E-29"
                     /label="IE274_RS38605_PKS_PP.2"
                     /locus_tag="IE274_RS38605"
                     /protein_end="2082"
                     /protein_start="1997"
                     /score="94.1"
                     /tool="antismash"
                     /translation="LAAASADERANLLIALVRDQAAAVLGHASADRVEDERGFLELGFD
                     SLTGVELRNRLMTATGLRLPATLVFQNRTPRALADRLAAD"
     aSDomain        6609..7259
                     /ASF="active site serine present: True"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38605_Thioesterase.1"
                     /evalue="1.10E-32"
                     /label="IE274_RS38605_Thioesterase.1"
                     /locus_tag="IE274_RS38605"
                     /protein_end="2418"
                     /protein_start="2201"
                     /score="106.2"
                     /tool="antismash"
                     /translation="FTSYVGRSSAYDYARFGAYFRDRRDVSVITHPGFLEGELLPADKE
                     ALVRLHADTVQRHTGGKPYVLAGHSSGGLVAHAVARELEERGAGPAGVVLVDTYVEEKA
                     LGDMAAAMGKQLSDRYDSAPDAEGAAVDADGDDWGDAWVTAMARYMFLGLLPDAIQAPT
                     LLVRASEPLMEWTQEYDWRPSWKLEHTAVDVPGTHFTVMEEHSATTARAVEAWL"
     CDS_motif       6795..6857
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38605_0013"
                     /evalue="1.10E-09"
                     /label="NRPS-te1"
                     /locus_tag="IE274_RS38605"
                     /protein_end="2284"
                     /protein_start="2263"
                     /score="30.7"
                     /tool="antismash"
                     /translation="PYVLAGHSSGGLVAHAVAREL"
     gene            complement(7472..9073)
                     /locus_tag="IE274_RS38610"
                     /old_locus_tag="GCM10010349_78850"
     CDS             complement(7472..9073)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024629.5"
                     /locus_tag="IE274_RS38610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_78850"
                     /product="glycosyltransferase family 39 protein"
                     /protein_id="WP_198898077.1"
                     /transl_table=11
                     /translation="MGVRTETGQVPEQEHEQDIKDQQTSSEPETENTGRQDGAEVGTGT
                     PPPFAGRWVGAVAGASGLALLLVSTRYGFQGDELYFLGAGKHLDWGFADQPVLLPLLAH
                     GIDAVTGGSLFALRLLPVLLTVAGALVAALIAREFGGERRAQLLTTAAYGFAPAVLISG
                     HALSTMALDLFLWTALNWLLIRWVRTREDRLLLFAGLATALALQGKYLIVGFWAVLAVC
                     LFVVGPRELLRRKPLWLGAAVAAVTSVPGLIWQAQNDWPQMEMSQVLADEGILGGRAGF
                     LPYLIVLSGGVFTVVLVYGLVRLLRAPQFAPYRFLGWAFLGLTAVFLVTGGRPAYVVGA
                     FAPLWAAGAVELARGGGARWWRWLAAWPVVALTALVCVALSLPVYPVSQVTKTEQPKNN
                     PMTAETLRWPHLIDAVDKANKALPAAERERAVVVTQYYQEAGAVDHFGPDRDLPPAYSG
                     HRGYWYFGAPADSSGPVLYVGSDVAKLKPYFKKVRKAATAAGGPGESFVDGVPVWILEG
                     RTKPWSKIWPDYGHLS"
     misc_feature    complement(9325..9339)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.07"
                     /tool="antismash"
     gene            9369..10805
                     /locus_tag="IE274_RS38615"
                     /old_locus_tag="GCM10010349_78860"
     CDS             9369..10805
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (8-371). E-value: 5.4e-69.
                     Score: 224.7. Matches aSDomain:
                     nrpspksdomains_IE274_RS38615_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642108.1"
                     /locus_tag="IE274_RS38615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_78860"
                     /product="class I adenylate-forming enzyme family protein"
                     /protein_id="WP_190120626.1"
                     /sec_met_domain="AMP-binding (E-value: 5.3e-65, bitscore:
                     208.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPHIFTGDSARTFAEFEQDTLRVAMVLRAEGIRPGDRVLLKAGN
                     SAAWLNAFFALMHVGASIVLVDQQEHARETGRIVERTRARLCLYDDDAPVPAETRDAVY
                     LYKLLVEASGLVPTEPALDFDAWCALPDGLIMWSSGSTGTPKGVVKNGGRFLENLRRNA
                     DHMGHGPGDVLLPLLPFAHQYGLSMVLISWLAKCSLVVAPHRRLDRALLMAGQCGVTVI
                     DATPATYRSMLNLAQRQSDVRAALGGVRMFCSGAAPLDPALSDAYVDAFGQPLLDSYGS
                     TELGNIAFATIDNPVACGRVMNGLRLTVQDDDGNALAAGEMGELVVNTPDMMAGYLAED
                     GTVAPVDQGWYRTGDLGHVDADGNLFVAGRKLAVHRMGYTLYPEIIERRAAAAGCAVKV
                     IALPDDARGSELVFFVEDASGRDAAEWRGRIKDALPSYEHPNRVVVIDSFPLNRNGKPD
                     RRALEQRAAERTTAELATSA"
     aSDomain        9393..10481
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38615_AMP-binding.1"
                     /evalue="5.40E-69"
                     /label="IE274_RS38615_AMP-binding.1"
                     /locus_tag="IE274_RS38615"
                     /protein_end="371"
                     /protein_start="8"
                     /score="224.7"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DSARTFAEFEQDTLRVAMVLRAEGIRPGDRVLLKAGNSAAWLNAF
                     FALMHVGASIVLVDQQEHARETGRIVERTRARLCLYDDDAPVPAETRDAVYLYKLLVEA
                     SGLVPTEPALDFDAWCALPDGLIMWSSGSTGTPKGVVKNGGRFLENLRRNADHMGHGPG
                     DVLLPLLPFAHQYGLSMVLISWLAKCSLVVAPHRRLDRALLMAGQCGVTVIDATPATYR
                     SMLNLAQRQSDVRAALGGVRMFCSGAAPLDPALSDAYVDAFGQPLLDSYGSTELGNIAF
                     ATIDNPVACGRVMNGLRLTVQDDDGNALAAGEMGELVVNTPDMMAGYLAEDGTVAPVDQ
                     GWYRTGDLGHVDADGNLFVAGRK"
     CDS_motif       9771..9815
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38615_0001"
                     /evalue="4.40E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="IE274_RS38615"
                     /protein_end="149"
                     /protein_start="134"
                     /score="16.3"
                     /tool="antismash"
                     /translation="IMWSSGSTGTPKGVV"
     gene            10899..11852
                     /locus_tag="IE274_RS38620"
                     /old_locus_tag="GCM10010349_78870"
     CDS             10899..11852
                     /EC_number="2.3.1.39"
                     /GO_function="GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_AT (11-285). E-value: 6.3e-15.
                     Score: 47.2. Matches aSDomain:
                     nrpspksdomains_IE274_RS38620_PKS_AT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642107.1"
                     /locus_tag="IE274_RS38620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_78870"
                     /product="ACP S-malonyltransferase"
                     /protein_id="WP_190120627.1"
                     /transl_table=11
                     /translation="MMTTDQARSAVVFPGMGPSRFTDVGKFMMIDPFVRKRLAAADDAL
                     GRSVLDEFRTAGTDFGAFAQVAFFINSVALADRAVETQGLAPDVCVGFSFGQKAATAFS
                     GALPFAEAVRLTHELALCEQRFFEEEHQDLVTLTITRVPAAALAEVLGELAERGEFHEV
                     SGHLDEGMHMVTMREQVLEPFQRRISAIGGYSLYSMKPPAHCRVLTGLRARVEEEVLAE
                     FDVADPELPLVADHDGALITRADQLRTLLLDTFDHPVRWHPVVDTLRGMDVRTVYVTGP
                     DRLIHRLDVTTRAFDVVALGPEQALRPARPASRKEQ"
     aSDomain        10932..11753
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38620_PKS_AT.1"
                     /evalue="6.30E-15"
                     /label="IE274_RS38620_PKS_AT.1"
                     /locus_tag="IE274_RS38620"
                     /protein_end="285"
                     /protein_start="11"
                     /score="47.2"
                     /specificity="substrate consensus: pk"
                     /specificity="PKS signature: (unknown)"
                     /specificity="Minowa: CHC-CoA"
                     /tool="antismash"
                     /translation="VFPGMGPSRFTDVGKFMMIDPFVRKRLAAADDALGRSVLDEFRTA
                     GTDFGAFAQVAFFINSVALADRAVETQGLAPDVCVGFSFGQKAATAFSGALPFAEAVRL
                     THELALCEQRFFEEEHQDLVTLTITRVPAAALAEVLGELAERGEFHEVSGHLDEGMHMV
                     TMREQVLEPFQRRISAIGGYSLYSMKPPAHCRVLTGLRARVEEEVLAEFDVADPELPLV
                     ADHDGALITRADQLRTLLLDTFDHPVRWHPVVDTLRGMDVRTVYVTGPDRLI"
     CDS_motif       11148..11243
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38620_0001"
                     /evalue="7.90E-05"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="IE274_RS38620"
                     /protein_end="115"
                     /protein_start="83"
                     /score="15.5"
                     /tool="antismash"
                     /translation="GLAPDVCVGFSFGQKAATAFSGALPFAEAVRL"
     CDS_motif       11328..11429
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38620_0002"
                     /evalue="8.10E+00"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="IE274_RS38620"
                     /protein_end="177"
                     /protein_start="143"
                     /score="-1.7"
                     /tool="antismash"
                     /translation="AAALAEVLGELAERGEFHEVSGHLDEGMHMVTMR"
     gene            11852..13123
                     /locus_tag="IE274_RS38625"
                     /old_locus_tag="GCM10010349_78880"
     CDS             11852..13123
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.5"
                     /locus_tag="IE274_RS38625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_78880"
                     /product="cytochrome P450"
                     /protein_id="WP_190120628.1"
                     /sec_met_domain="p450 (E-value: 4.7e-24, bitscore: 74.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATLMDSKSAGFKFSAKLGATRAILRAFGVFGDPFTRLLQGQEDP
                     YPLYAKVRQRGPVHRSHLGTWVTGSHELGSRILRDRTLFLNREQGGVPGHEMMAEIPWN
                     SSILGLDPPDHTRLRRLAQPAFGPRMISKYRVQVEKLCNGLLDELSARDGFDLIEDFAG
                     PLPLLVIGELLGVPEEYHDRFIRAGRKVGPVIDGVKSLKMARDFRGAVDDLDQVFTELI
                     ELRAKDPGDDLISRLTVANEEGKLSTEELLAFCTVLAVTGFETTTNLIGNAVLAMTGDR
                     AQWDLLREDPDLAPRAVEETLRYDSPALQAQRVPHGDIALAGHHIRANSSVVVLIGAAN
                     RDPEVYDDPDRFDLTRENPAEHLSFSGGIHYCIGAPLARMEGETALRVLAERLPDLRVA
                     GPVVRRSSPVISGCTRLPVSGKPG"
     gene            13246..14364
                     /locus_tag="IE274_RS38630"
                     /old_locus_tag="GCM10010349_78890"
     CDS             13246..14364
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642105.1"
                     /locus_tag="IE274_RS38630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_78890"
                     /product="agmatinase family protein"
                     /protein_id="WP_190120629.1"
                     /transl_table=11
                     /translation="MSETPESEAWRREVDRSTFPRRDPGPIDLRRYYVQPSYSGVPTFM
                     GVPLALNQEDLRAGGVDVAVVGCPVDVSSGHRGAAYGPRAIRADERYLYATPEGFVHSA
                     TRVNPFNVLKVVDYGDAAVDPFDITRSMEPIRGLVREIAEVGARPVVLGGDHSLLWPSV
                     GALSEVHGRGSIAVIHFDAHPDCHEELFGHRATHTTPIRRLIDEEMVPGPNIIQVGIRT
                     ISGPDDQLFNWMRRAGMRSHFMAEIERIGFPAVIDKVIEEARAVADHVYLSLDIDVLDP
                     AYAPGTGTPEPAGLNTRELFMALRRIAHETDLIGMDVVEVAPHLDAGYSTAMNARRAVF
                     EALTGLALNRIKISSKNYANPIVAGEVRFPLR"
     gene            14535..15284
                     /locus_tag="IE274_RS38635"
                     /old_locus_tag="GCM10010349_78900"
     CDS             14535..15284
                     /NRPS_PKS="Domain: Thioesterase (22-241). E-value: 1.4e-62.
                     Score: 204.0. Matches aSDomain:
                     nrpspksdomains_IE274_RS38635_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016575111.1"
                     /locus_tag="IE274_RS38635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_78900"
                     /product="thioesterase II family protein"
                     /protein_id="WP_190120630.1"
                     /sec_met_domain="Thioesterase (E-value: 2.8e-65, bitscore:
                     209.9, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 8.3e-14, bitscore:
                     41.9, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTAASADLWVRSYHPAPDATARLVCFPHAGGSASFYFPVSAALS
                     TVADVVAVQYPGRQDRHTEKGIESIAELADRAADALRSHDDSLPLTFFGHSMGAVLAFE
                     VARRLERDGRAPVHVFASGRRAPSSHRPENVHQRDDDGVIAEMRKLSGTDPRVLGDDEV
                     LRMVLPAIRSDYTAIETYRAEPGAQIGSPITVLVGDDDPRTTLDEARAWEPHTLGTFDM
                     KVFPGGHFYLTDHAQEVIAVLKAHFTS"
     aSDomain        14601..15257
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38635_Thioesterase.1"
                     /evalue="1.40E-62"
                     /label="IE274_RS38635_Thioesterase.1"
                     /locus_tag="IE274_RS38635"
                     /protein_end="241"
                     /protein_start="22"
                     /score="204.0"
                     /tool="antismash"
                     /translation="RLVCFPHAGGSASFYFPVSAALSTVADVVAVQYPGRQDRHTEKGI
                     ESIAELADRAADALRSHDDSLPLTFFGHSMGAVLAFEVARRLERDGRAPVHVFASGRRA
                     PSSHRPENVHQRDDDGVIAEMRKLSGTDPRVLGDDEVLRMVLPAIRSDYTAIETYRAEP
                     GAQIGSPITVLVGDDDPRTTLDEARAWEPHTLGTFDMKVFPGGHFYLTDHAQEVIA"
     CDS_motif       14799..14861
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38635_0001"
                     /evalue="6.60E-09"
                     /label="NRPS-te1"
                     /locus_tag="IE274_RS38635"
                     /protein_end="109"
                     /protein_start="88"
                     /score="28.2"
                     /tool="antismash"
                     /translation="PLTFFGHSMGAVLAFEVARRL"
     gene            complement(15450..15650)
                     /locus_tag="IE274_RS38640"
                     /old_locus_tag="GCM10010349_78910"
     CDS             complement(15450..15650)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE274_RS38640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010349_78910"
                     /product="hypothetical protein"
                     /protein_id="WP_190120631.1"
                     /transl_table=11
                     /translation="MLWVGIVLAVQGFGSFLTERIWDTKFGVTALLGDDSPSWVGLAIG
                     VVGLVILAFCASSRTRKSVHN"
     gene            16029..>16242
                     /locus_tag="IE274_RS39945"
     CDS             16029..>16242
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE274_RS39945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_229910114.1"
                     /transl_table=11
                     /translation="MQSARTSGEKSDDESGKPSVFRPTATDITLLTALVVLNVFVAVWN
                     ETHQEGHPRFGPWAGLGLQVVVVVVL"
ORIGIN
        1 tcgtgctgtt ctcgtcggct gctggtgtgc tgggcagtgc ggggcaggcc aactacgcgg
       61 ccgctaatgc cttcttggac gcgctggctc agcaccgtcg tgcccagggt cttcctgcga
      121 cgtcgctcgc gtgggggctg tgggcggacc agggtggcat ggccggggcg ttggcggacg
      181 aggacatcga ccggatgaac cgggccggag tcgccgccct gtccgccgac gagggcctcg
      241 cgctcctcga cgcctccctc gcggagcccg acggcgccct cgtcccgatg aagctcgaca
      301 ccgacatcct gaggcagcag ttcggcgccg acgtgccccc gctgttccgg agcctcatcc
      361 gcgcccaggt ccgcaaggcc gtcaccgcgc aggcgggcgg cgcggcggcc aacggccagg
      421 aacccctggc cgaccgcctc gccggactcg acgcggcgga ccgcgaacag ttcctcgtcg
      481 acctcgtacg ggccaacgtg gccgccgtcc tcggctaccc gtcgcccgaa tccgtcgacg
      541 ccgccaaggc gttcaaggaa ctcggcttcg actcgctgac ctccgtcgaa ctccgcaacc
      601 ggctcaacgg cgccaccgcc ctgcggctgc ccgcgagcct cgtcttcgac taccccacgc
      661 ccgtcgccct cgccgcccac ctgcgcacgg aactcctcgg ctcgctcccc gagaccgccg
      721 ccccgagcgc caccaagggc cggaaggaca ccccgcggga cgcggccgac gagcccatcg
      781 ccatcgtcgc gatgagctgc cgctaccccg gcggcgtccg ctcgcccgag gacctgtggc
      841 gcatggtggc cgccggtgcg gacggactga ccgggttccc cgtcaaccgg ggctgggacg
      901 tcaccgcccc cgcgggcctc gacggcccgg gcgcggacgg cgacgacggc ctgacgtacg
      961 tcacgaccgg cgccttcctg cacgaagccg acgagttcga cccggacttc ttcggcatca
     1021 accaccgtga ggccctggcc atggacccgc agcagcggct cctcctggag acctcctggg
     1081 aggccgtcga acgcgcgggc atcgtcccgt cgaccgtgcg cgccagcgac accggcgtct
     1141 tcgtcggcct gtcgacgcag ggctactcca ccaccctcaa cggcgccgag ggcgtcgagg
     1201 gctacgtcat gaccggcgac gcggccagcg tcgcctccgg ccgcctctcg tactccttcg
     1261 gcttcgaggg cccggccgtc acggtcgaca cggcctgctc gtcgtccctg gtcgccctgc
     1321 acctcgccgt gcaggcgctg cgccagggcg agtgcgcgat ggcgctcgcg ggcggcgcgg
     1381 cggtcatgcc gacgcccacc tccttcgcgg agttcagccg ccagcgcggc ctggcccccg
     1441 acggccgctg caagtccttc gccgcggccg cggacggcac cggctggggc gagggcgtgg
     1501 gcatgctcgt cctggagcgc ctgtccgacg cccagcgcaa cggccaccag gtcctcgcgg
     1561 tggtccgcgg ctcggcgatc aaccaggacg gcgccagcaa cggcctgacc gcccccaacg
     1621 ggccgtccca gcagcgcgtc atccgccagg ccctcgccaa cgcccgcctc acccccgccg
     1681 acgtcgacgc ggtcgaggcc cacggcaccg gcaccacgct cggcgacccc atcgaggccc
     1741 aggccctcat cgccacgtac ggaaaggacc acaccgacga ccggccgctg tggctcggct
     1801 cgctgaagtc caacatcgcc cacacccagg ccgccgccgg tgtcggcggc gtcatcaaga
     1861 cggtcatggc gatgcgccac ggcaccctgc cgaagacgct gtacgtggac gccccgaccc
     1921 ccgaggtcga ctggtccggc gcgggcgtcg agctcctgac cgaggcccgt gactggcccg
     1981 gacgggagga cggggcgccg cgccgcgcgg gcgtgtcgtc gttcggcatc agcgggacga
     2041 acgcgcacgt gatcctggag caggctcccg aggaggccgc ggaagccgcc gggtccacgg
     2101 cgaccgccgg atccaccgcc gccccggccc tctccgggcc ccccgtcatc cccctcgccc
     2161 tgtccgccaa gaccccggag tcgctcccgg gccaggccgc ccgcctgcgg gagcacctcc
     2221 tggcgcaccc cgacctcgaa ctcggcgacg tcgcctggtc gttggcggtg gcgcggcagc
     2281 ggttcgagca ccggggcgtc gtcgtcggcg cggaccggga cgaactgctg gccgggctcg
     2341 cggagctggc ccagggcgac accgccgcgc ggaacgtggt tgtgggtcgc acgctgggcg
     2401 gcacggtccg tccggtgttc gtgttcccgg ggcaggggtc gcagtgggcc gggatggcgc
     2461 gtgaactcct cgactccagc ccggtgttcg ccgagcgcat gcgggagtgc ggtgacgcgc
     2521 tttccgagtt cgtcgactgg aacctgttcg acgaactgag cggtgagcgg ttcgaccggg
     2581 tggatgtcgt ccagccggtg ctgttcgccg tgatggtgtc gctggccgcc acctggcagg
     2641 ccgccggagt cgagcccgca gccgtcgtcg ggcacagcca gggcgagatc gccgccgcgt
     2701 gcgtcgcggg cgtcctcggc ctgcgcgacg ccgcccgcgt cgtggccctg cgcagccagg
     2761 ccatccgcga gctgtccggc aagggtggca tggtctccct cgtcctgccg caggacgaga
     2821 cccggacgct cctggaggcc tgggacggcc gcatcgagat cgccgccgtc aacggcccct
     2881 cccaagtcgt ggtctccggc gaccccgaag ccctcgaaga gctgatcgcc gagtgcgccg
     2941 cacgggaact ccgcgcccgc gccatccccg tcgactacgc ctcccactcc tcgtacgtcg
     3001 agcagatcga ggcccgcatc gacgaggcgc tggccgaggt ggcgccgagc gccgcccgga
     3061 ccccgctgta ctcgaccctc accggcgcct ggctggacgc cgacaccccg atggacgccg
     3121 ggtactggta ccgcaacctg cgccacaccg tcctcttcga gcaggccacc cgcgccctcc
     3181 tcaccgaggg ccacgggctg ttcctggaga tgagcccgca cccggtcctc accgtcccgg
     3241 tgcaggagac catcgacgcc accgcgccca ccggcgcggt cgcgctgggc tccctgcgcc
     3301 gcgacgaggg cggccccgac cagctgtacg ccgccctcgc cgcggcacac gtccacggcg
     3361 ccgaactcga ctggcgggcc ctcctgcccg gcgagcgcgc cgtcgtcgac ctgcccacgt
     3421 acgccttcca gcggcagcgc ttctggcccg cgcccgccgc ggcgggcacc ggcgacgtca
     3481 ccgccgtcgg catcgagtcc gccggacacc ccctgctcgg cgccagcgtg gaactcgccg
     3541 acgccgatca gtacctgctc accggacggc tcacccgccg cacccacccc tggctcgcgg
     3601 accacgcggt gggcgacacc gtgctgctgc ccggcaccgc gtacgtcgag atggcactgc
     3661 gcgccgggga cgaggtcggc tgcggcctcg tcgaggagct gaccctgcag gcgccgctcg
     3721 tcgtcgccga ggacgacacc gtcacgctcc aggtgtgggt cggcgccccc gacaccgcgg
     3781 ggcggcgccc gctcaccgtg tcctcgcgga cccagggcgc caccgacacc ccgtggacgc
     3841 ggcacgccac cggcaccctc gccgacacgt ccggcgcgcc cgcccaggag gacggggcgc
     3901 tggccgtgtg gccgcccgcg ggcgccgagg cggtcgccgt cgacgggttc tacgagcgcc
     3961 tcgccgaggg cgggctcgcc tacggcccgg cgttccaagg gctgcgcgcc gcctggcggg
     4021 acccggcggg cgatgccgtc tacgccgagg tccacctccc cgaggacgcg caccgcgacg
     4081 cccgcgcgtt cggcgtgcac ccggcgctcc tcgacgccgc cctgcacgcc gtcgccctcg
     4141 cgcccttcgc ggaggccgac ggggtgcggc tgcccttcgc ctggagcggc gtcacgctgg
     4201 ccgcgcaggg cgccaccgtc ctgcgggtcc gggtacgccc cgacggcacc gggggagtgg
     4261 cgctcctgtt cgccgacgac aacggcgcgc cggtcgcccg cgccgactcc ctcgaactgc
     4321 gccccgtcgc ccccgggcaa ctgcgcgcgg cctctggtgg cggacaccgg gacgccctgt
     4381 tccacgtcga gtggacgccg ctgcccgcgg ccacgccggc cgacgtggcg ggcacgacgt
     4441 gggcgacggt cggtcccgac ccgctgacgg cgggcgccga actcacggcg tccggcgcgc
     4501 agatggcggc gtacgaggac atcgacgcgc tgtacgcggc cctcgacgac ggcgcggacg
     4561 caccggacac gctgctcgtc tccttcacgg acgggccggg cgccgagggg ccggacggga
     4621 cggcggactc cctggacgcc gtggccaccg ccgagcgtgc ccgcgccgcc ctgggccggg
     4681 ccctcgccct gctccagacc tggcaggccg acgcgcgcct gtccgccacc cggctcgtcc
     4741 tggtgacgcg gggcgcggtg gccgccgacg gcggcgacgt gccggacctg gcgcacgccc
     4801 cgctgtgggg cctggcacgc tcggcccagt ccgagcaggc cggtggcccg gacggggccg
     4861 ggtgcgtgct gttcgacctg gacgcggcgt acggcgtcga cggcgcgggc agcccggccg
     4921 ccgagggcga cgcggacgcc gagggcacgc ccgcccgccc ggccgaccag tccgccgccg
     4981 cccttctcat cgccggactc gccctggacg agccgcagtt ggcggtgcgc gagggagtgc
     5041 tgctcgcacc ccggctcgtg cccgccacgg ctccggcgac gacaccggcc gtcgacggcg
     5101 gcgccgacac caccgaggcc ggcgcccccg agggcacggc gcccaccgcg ccccgcaccc
     5161 ccgaccccca cggcaccgtc ctcatcaccg gcgccaccgg caccctgggc gccctcgtcg
     5221 cccggcacct ggtcaccgag cacggcgccc gccgactgct cctgaccggc cgccggggcc
     5281 ccgacgcgcc gggcgccgcc gagctggtcg ccgagctcga agggctcggc gccgaggccc
     5341 gcgtggtcgc ctgcgacgtc gcggaccgcg aggcgctggc cggggtgctc gccgcgatcc
     5401 cggcggcgca cccgctgacc gccgtcgtgc acaccgccgg agtcctggac gacgccctcg
     5461 tggggtccct gacgcccgcg cgcctggaca cggtgctccg ccccaagctg gacgcggcac
     5521 tgaacctcgc cgagctgacg gccaatcagg accttgcgga gttcgtcctg ttctcctcgg
     5581 ccgccgccac cttcggcagc cccggacagg gcaactacgc ggcggccaac gccttcctcg
     5641 acgccttcgc acaccatctg cgcgcccggg gcatacccgc cacggcgctc gcctggggcc
     5701 tgtgggccga gagcagcgag atgaccggcc acctcgacga ggcgcgccgc acccgcatct
     5761 cacgcggcgg tgtgctgccg ctgtcctcgc gggagggcgt cgaactcttc gacaccgccc
     5821 gctcgtccgg cgccccgctg ctccttcccg tacgcctcga cacggcggcc ctgcgggcgg
     5881 gcgcgcgcca gggtgaggcc gtgccgccgc tgctgcggcg cctggtgcgg gcccaggccc
     5941 gccgggccgc cgccggggcc gcggcgtcgg aggcggaggc tttcgcgcgc cgcctggccg
     6001 ccgcgtccgc cgacgagcgc gcgaacctcc tcatcgccct ggtgcgcgac caggcggcgg
     6061 ccgtactcgg ccacgcctcc gccgaccggg tcgaggacga acgcggcttc ctggagctgg
     6121 gcttcgactc cctcaccggc gtcgaactgc gcaaccgcct catgaccgcc accggcctgc
     6181 ggctcccggc caccctggtc ttccagaacc gcacgccgag ggccctcgcc gaccgcctcg
     6241 ccgccgacct ggaccaggcc gtgcccgcgg gccaggaccc ggcgaccccg cgcgagcgga
     6301 ccgccggaca gccgcagcac acccggacgg cccccgccgc ccggcagccc gccgcggcat
     6361 cgacggccac cgccgacgcg caccgggccg aggccgtccc gcggcccgtc gccgcgccca
     6421 ggcccgcgac cggtctcgcc gagctgtacg acgaggccgc gcggcagggc cgggccgacg
     6481 acctgatccc gctcctgcgg accatggcgc agttccgcgc ctcgttcacg ggcgagggcg
     6541 aactcgacgt gccgcgcgcc ccgttcacgc tggcgcgcgg cgaggagccg gtcggcgtgg
     6601 tgctgttcac gtcgtacgtc ggccgctcca gcgcctacga ctacgcccgc ttcggcgcgt
     6661 acttccgtga ccggcgcgac gtcagcgtca tcacccaccc cggcttcctg gagggcgagt
     6721 tgctgcccgc cgacaaggag gcactggtgc ggctgcacgc cgacaccgtg cagcggcaca
     6781 ccggcggcaa gccgtacgtc ctcgccgggc actcctccgg cgggctcgtc gcgcacgccg
     6841 tggcacggga gctggaggag cgcggcgccg gtcctgcggg cgtggtcctc gtggacacgt
     6901 acgtcgagga gaaggcgctc ggcgacatgg ccgccgccat gggcaagcag ctcagcgacc
     6961 gctacgactc cgcaccggac gccgagggcg cggcggtgga cgccgacggt gacgactggg
     7021 gcgacgcctg ggtcaccgcc atggcccgct acatgttcct cggcctgctg cccgacgcca
     7081 tccaggcgcc gacgctcctg gtccgggcga gcgagcccct catggagtgg actcaggagt
     7141 acgactggcg gccgtcctgg aagctggagc acaccgcggt ggacgtgccc ggcacgcact
     7201 tcacggtgat ggaggagcac tccgccacca cggcccgcgc cgtcgaggcg tggctggacc
     7261 gcctctgacc cagcggcacc acggccccgt ccccgcacag cgcgggggcg gggccgtcgg
     7321 cgtacccccg ccaaggcgta cgagaaggcg tacgagtcgg cgtgcacccg tcaaggcgta
     7381 cgcgccaccc gtcaaggcgt acgtgccacc cgcacgaaga aggcccgccc ccggcttcct
     7441 ccgcgggggc gggccttcgc tcggcgaggt ctcaggacaa gtggccgtag tccggccaga
     7501 tcttggacca gggcttggtg cggccctcca gaatccacac cgggacgccg tcgacgaagc
     7561 tctcgccggg gccgcccgcg gccgtcgcgg ccttgcgcac cttcttgaag tacggcttga
     7621 gcttggcgac gtcggagccc acgtacagga ccgggcccga ggagtcggcc ggcgcgccga
     7681 agtaccagta gccgcggtgg ccgctgtagg cgggcggcag gtcgcggtcg gggccgaagt
     7741 gatcgacggc gcccgcctcc tggtagtact gcgtgaccac cacggcccgc tcccgctcgg
     7801 cggcgggcag tgccttgttg gccttgtcga ccgcgtcgat gaggtgcggc cagcgcagcg
     7861 tctcggcggt catcgggttg ttcttcggct gctcggtctt cgtcacctgc gacaccggat
     7921 acaccggcag cgagagcgcc acgcacacca gcgccgtcag ggccaccacc ggccacgcgg
     7981 ccagccaccg ccaccagcgg gccccgccac cgcgcgccag ctccaccgcg cccgccgccc
     8041 acagcggcgc gaaggcgccc acgacgtacg cgggacggcc gccggtgacc aggaacacgg
     8101 ccgtcagacc gaggaacgcc cagcccagga agcggtacgg cgcgaactgc ggcgcccgca
     8161 ggaggcggac caggccgtag accaggacga cggtgaacac gccgccggac aggacgatca
     8221 ggtacggcag gaagcccgcg cggccgccga gtatgccctc gtcggcgagg acctgggaca
     8281 tctccatctg cggccagtcg ttctgcgcct gccagatcag ccccggcacc gacgtgacgg
     8341 ccgcgaccgc cgcacccagc cacagcggct tgcggcgcag cagctcgcgc ggtccgacca
     8401 cgaacaggca cacggcgagc acggcccaga agccgacgat cagatacttg ccctgcagcg
     8461 ccagggccgt cgcaagcccc gcgaacagca gcagccggtc ctcgcgggtg cgcacccagc
     8521 ggatcaggag ccagttcaga gccgtccaca ggaacaggtc gagcgccatc gtcgacagcg
     8581 cgtgcccgct gatcaggacg gcgggcgcga agccgtaggc ggccgtcgtg agcagctgcg
     8641 cacggcgctc cccgccgaac tcgcgggcga tgagggcggc gacgagggcg cccgccaccg
     8701 tgagcagcac cggcagcagc cgcagcgcga acagcgagcc gccggtcacc gcgtcgatgc
     8761 cgtgggcgag cagcggcagc agcaccggct ggtccgcgaa cccccagtcc aggtgcttcc
     8821 cggcgccgag gaagtacagc tcgtcgccct ggaagccgta ccgcgtgctg accaggagca
     8881 gcgcgagacc ggacgcgccc gcgaccgcgc ccacccagcg tccggcgaac ggcggcggcg
     8941 tgccggtgcc cacctccgcg ccgtcctgcc gccccgtatt ttccgtctcg ggttccgacg
     9001 acgtctgctg gtctttaata tcctgttcgt gttcctgttc cggtacttga ccggtctctg
     9061 tccgaactcc caccgggacc tccgcggctt atgcggtaca tggcgtaatc accgtcgaag
     9121 gtagcgcctg gcacgtcccg tcagcttgcc cctgcaaccg gcaagttggc tgctcagggg
     9181 gggctagggg gaagataggg gttctgctgc tcaggcacgc tgaatagctt ctaccgtagg
     9241 tcctcggaga cttgactccg cgcggagtcg accggggcgc aatgaatgct cgaccttatc
     9301 gtgcctatcg agcccatcgt gcctatcgag cccgatgatt ctcagatctg ggaaaggggg
     9361 cggctttgat gacacctcac atattcaccg gggattcggc gcggaccttc gccgaattcg
     9421 agcaggacac cttgcgggtc gcgatggtcc tgcgcgcgga gggcatccgg ccgggagacc
     9481 gggtgctgct caaggccggg aactcggccg cctggctgaa cgcgttcttc gcgctgatgc
     9541 acgtcggcgc ctccatcgtc ctcgtcgacc agcaggagca cgcgcgcgag accggccgca
     9601 tcgtcgagcg cacccgcgcc cggctgtgcc tgtacgacga cgacgccccc gtacccgcgg
     9661 agacgcgcga cgccgtctac ctgtacaagc tgctcgtcga ggcgtccggc ctggtcccca
     9721 ccgagccggc cctggacttc gacgcctggt gcgccctgcc cgacggcctg atcatgtggt
     9781 cctccggctc caccggcacc cccaagggcg tcgtgaagaa cggcggccgc ttcctggaga
     9841 acctgcggcg caacgccgac cacatgggcc acggccccgg cgacgtgctg cttccgctgc
     9901 tgcccttcgc gcaccagtac ggcctgtcga tggtcctcat ctcctggctc gccaagtgct
     9961 ccctcgtcgt cgcgccccac cggcgcctcg accgggccct gctcatggcc gggcagtgcg
    10021 gcgtcaccgt catcgacgcc accccggcca cgtaccgcag catgctcaac ctcgcccagc
    10081 gccagtccga cgtgcgcgcc gccctgggag gcgtccgcat gttctgcagc ggcgcggccc
    10141 ccctcgaccc ggccctctcc gacgcctacg tcgacgcctt cgggcagccg ctgctcgaca
    10201 gctacggcag caccgagctc ggcaacatcg ccttcgccac catcgacaac ccggtcgcct
    10261 gcggccgtgt catgaacggc ctgcgcctga cggtgcagga cgacgacggc aacgcgctcg
    10321 ccgccgggga gatgggcgag ctcgtcgtca acacccccga catgatggcc ggttacctcg
    10381 ccgaggacgg caccgtcgcc cccgtcgacc agggctggta ccgcaccggc gacctcggtc
    10441 acgtcgacgc cgacggcaac ctcttcgtcg cgggccgcaa actcgccgtg caccgcatgg
    10501 gctacaccct ctacccggag atcatcgagc ggagggccgc cgctgcgggc tgcgccgtca
    10561 aggtgatcgc cctgccggac gacgcgcgcg gctccgaact cgtcttcttc gtcgaggacg
    10621 cgagcggccg ggacgccgcc gagtggcgcg gccgcatcaa ggacgcgctg ccctcgtacg
    10681 agcaccccaa ccgggtcgtc gtcatcgaca gcttccccct caaccgcaac ggcaagcccg
    10741 accgccgcgc gctcgagcag cgggcggccg agcggaccac ggcggaactc gccacctcgg
    10801 cctgagcccc gcacggccat ccggacccgg gccgggccgc agctcaacca gccataccag
    10861 ccacaccagc tagaccaggc agaccagaca gagcggacat gatgacgacc gaccaggcac
    10921 gcagcgccgt ggtgtttccg ggcatgggcc cctcgcgctt caccgacgtg ggcaagttca
    10981 tgatgatcga ccccttcgtg cgcaagcgcc tcgccgccgc cgacgacgca ctggggcgct
    11041 cggtcctgga cgaattccgc accgcgggaa cggacttcgg cgcgttcgcc caggtcgcct
    11101 tcttcatcaa ctcggtggcc ctggccgacc gggccgtcga gacccagggc ctcgccccgg
    11161 acgtctgcgt cggcttcagc ttcggccaga aggccgcgac cgcgttcagc ggggcgctgc
    11221 cgttcgccga ggccgtccgc ctcacccatg aactcgccct gtgcgagcag cggttcttcg
    11281 aggaggagca ccaggacctg gtgacgctca ccatcacccg ggtccccgcg gcggcgctcg
    11341 ccgaagtcct cggggagctg gccgagcgcg gcgagttcca cgaggtctcc ggccacctcg
    11401 acgagggcat gcacatggtc acgatgcgcg aacaggtcct ggagcccttc cagcgccgca
    11461 tcagcgcgat cggcggctat tcgctgtact cgatgaagcc gcccgcgcac tgccgcgtcc
    11521 tcaccggact gcgggcccgc gtcgaggagg aggtcctcgc cgagttcgac gtcgccgacc
    11581 ccgaactgcc gctggtcgcc gaccacgacg gtgccctgat cacgcgcgcc gaccaactgc
    11641 gcaccctgct tctcgacacc ttcgaccacc cggtccgctg gcacccggtc gtggacaccc
    11701 tgcgcggcat ggacgtgcgc acggtctacg tcaccggccc ggaccggctc atccaccgcc
    11761 tcgacgtcac cacccgcgcc ttcgacgtgg tggcactggg accggagcag gccctccggc
    11821 ccgccaggcc cgcctctcgc aaggagcagt gatggccacg ctcatggaca gcaagtcggc
    11881 cgggttcaag ttcagcgcca agctcggcgc gacccgtgcg atcctgcgcg ccttcggcgt
    11941 gttcggcgac ccgttcaccc gcctgctgca gggccaggag gacccgtacc cgctgtatgc
    12001 gaaggtacgg cagcggggcc ccgtgcaccg cagccacctg ggcacctggg tcaccggcag
    12061 ccacgagctc ggcagccgga tcctgcggga ccgcaccctg ttcctcaacc gcgagcaggg
    12121 cggcgtgccc ggccacgaga tgatggccga gatcccctgg aacagctcca tcctcggcct
    12181 cgacccgccc gaccacaccc gcctccgccg tctcgcgcag cccgccttcg gtccccggat
    12241 gatcagcaag taccgggtcc aggtggagaa gctctgcaac ggcctgctcg acgagttgtc
    12301 cgcccgcgac ggcttcgacc tcatcgagga cttcgccggg cccctgccgc tcctggtgat
    12361 cggggagctc ctcggcgtcc ccgaggagta ccacgaccgg ttcatccgcg ccgggcgcaa
    12421 ggtcgggccc gtcatcgacg gcgtcaagtc cctgaagatg gcacgggact tccgcggcgc
    12481 cgtcgacgac ctcgaccagg tcttcaccga gctgatcgaa ctgcgcgcca aggaccccgg
    12541 tgacgacctc atcagccgcc tcaccgtggc caacgaagag ggcaagctca gcacggagga
    12601 actcctcgcc ttctgtacgg tcctcgccgt caccggcttc gagaccacca ccaacctcat
    12661 cggcaacgcc gtcctcgcga tgaccggcga ccgcgcccag tgggacctgc tgcgtgagga
    12721 ccccgacctg gcgccgcgcg ccgtcgagga gaccctgcgc tacgactcgc ccgccctcca
    12781 ggcccagcgc gtcccgcacg gcgacatcgc gctcgcgggt caccacatcc gggccaacag
    12841 ctccgtggtc gtcctcatcg gcgccgccaa ccgcgacccc gaggtgtacg acgacccgga
    12901 ccgcttcgac ctcacccgcg agaacccggc cgagcacctg tcgttctccg gcggcatcca
    12961 ctactgcatc ggcgccccgc tggcccgcat ggagggcgag accgcgctgc gcgtcctcgc
    13021 cgaacggctg ccggacctgc gcgtcgccgg gcccgtggtg cgccgcagtt cgccggtgat
    13081 cagcggctgt acccggctgc ccgtgagcgg caagcccggg tgagaccggt cgctggtgcc
    13141 tcctggtgag caccccccgg tgagagacga ccacccgcag caccggcggg ccacgcccac
    13201 gggcgccgcc ccgccgggta cgaacccgcg tatccgagga gagagatgag cgagacaccc
    13261 gagtccgagg cctggcggcg ggaggtcgat cgctccacct tcccgcggcg cgaccccggc
    13321 cccatcgacc tgcgccgcta ctacgtccag ccgtcctact cgggcgtgcc caccttcatg
    13381 ggcgtccccc tcgccctcaa ccaggaggac ctgcgcgcgg gcggcgtgga cgtggccgtg
    13441 gtgggctgcc ccgtggacgt ctccagcgga caccgcggcg ccgcctacgg cccgcgcgcc
    13501 atccgcgccg acgagcgcta cctgtacgcc acgcccgagg gcttcgtgca ctccgcgacc
    13561 cgcgtcaacc cgttcaacgt cctcaaggtc gtcgactacg gcgacgcggc cgtcgacccc
    13621 ttcgacatca cccggtccat ggagcccatc cgcggcctgg tccgcgagat cgccgaggtc
    13681 ggggcgcggc ccgtcgtgct cggcggcgac cactcgctgc tgtggccgag cgtcggcgcg
    13741 ctctccgagg tgcacgggcg cggctccatc gccgtcatcc acttcgacgc gcaccccgac
    13801 tgccacgagg agctgttcgg gcaccgcgcc acccacacca cgccgatccg ccgtctcatc
    13861 gacgaggaga tggtgccggg gccgaacatc atccaggtcg gcatccgcac catctccggc
    13921 ccggacgacc agctcttcaa ctggatgcgg cgggccggga tgcgctcgca cttcatggcg
    13981 gagatcgagc gcatcggctt cccggcggtc atcgacaagg tcatcgagga ggcccgcgcg
    14041 gtcgccgacc acgtctatct gtccctggac atcgacgtcc tcgaccccgc gtacgcccct
    14101 ggcaccggca cccccgagcc cgccgggctc aacacccgcg aactgttcat ggccctgcgc
    14161 cggatcgccc acgagaccga cctgatcggc atggacgtgg tcgaggtcgc cccgcacctg
    14221 gacgcgggct actccaccgc catgaacgcc cgcagggccg tcttcgaggc cctgaccggc
    14281 ctggcgctga accgcatcaa gatctccagc aagaactacg cgaacccgat cgtggccggt
    14341 gaagtccgct tcccgctgcg ctgaggtcgg atgaagtccg ggcgcgcacg gcgcgtaccg
    14401 cgcacgcgcc gaaggcgggc cacggcccgc cttcggcctg tttgcctgcc cctttcagcg
    14461 accccgctct cagcagtccc gttccgagca gtcttttcag cagtcccgcc gacgaccatg
    14521 gatggaaccc cgtcatgacg accgccgcct ccgccgacct gtgggtccgc agctatcacc
    14581 cggcccccga cgccaccgcc cgactggtct gcttcccgca cgcgggcggc tcggccagct
    14641 tctacttccc cgtctcggcc gccctgagca ccgtcgccga cgtcgtcgcc gtgcagtacc
    14701 cgggccgcca ggaccgccac acggagaagg gcatcgagtc catcgccgag ctggccgacc
    14761 gggccgcgga cgccctgcgg agccacgacg actcgctgcc gctgaccttc ttcggccaca
    14821 gcatgggcgc cgtgctcgcc ttcgaggtgg cccgccgcct ggagcgggac ggccgcgccc
    14881 cggtgcacgt cttcgcctcc ggccgccgcg ccccctccag ccaccgcccg gagaacgtcc
    14941 accagcgcga cgacgacggc gtcatcgccg agatgcgcaa gctcagcggc accgacccgc
    15001 gggtcctcgg cgacgacgag gtgctgcgca tggtgctgcc cgccatccgc agcgactaca
    15061 ccgccatcga gacctaccgc gccgaacccg gcgcgcagat cggcagcccc atcaccgtcc
    15121 tggtcggcga cgacgacccg cgcaccaccc tcgacgaggc ccgcgcctgg gagccgcaca
    15181 ccctgggcac cttcgacatg aaggtgttcc ccggcggcca cttctacctg accgaccacg
    15241 cccaggaagt catcgccgtc ctgaaagcgc atttcacgtc gtaaaacgcc acttggcggg
    15301 tcgttcgtcg catgctctgc gacgaacgac ccgccaagtc gtttcataca tgaagaaacc
    15361 cggtggccag ttacggggga gaaccggcca ccgggagctt ggcccctgcg gcagcagggg
    15421 agagaaatac acccggggga ggggggattt cagttgtgta cggacttacg ggtacgtgaa
    15481 ctcgcgcaga acgcaaggat gacgagaccg accacgccga tcgccaggcc cacccacgag
    15541 gggctgtcgt cacccaggag tgccgtgaca ccgaattttg tgtcccaaat acgctcggtc
    15601 aggaatgaac cgaatccctg aaccgccagg acgatgccga cccacagcat gtcgctcctc
    15661 aaatgatctg ttcgggtgag cagtcttgtt gcttcttgcg ccgcgccccg gccggtggtg
    15721 ttcctgccgg gctgccaaca agacttattc aaccgcttga cgcggggggc caggcagagg
    15781 gaaacgttgc tatccctacc gacgaaagta gtgaccggcc gtggcgttcc ccctctcgtg
    15841 gacctggtgt gccgggggcg gaaggtgcac ggctcccgcc ccgcaggcgt tggccagggg
    15901 tcgcgaaagc cgctaagagg gcactgaagt cgcaggtcag ggccgtgggt agggcctagc
    15961 gtcagtacgc attaagctct ggacgaccca cagagcgcga agccgacatg tacgggggtg
    16021 ggcttgtcgt gcaatcagcc aggacgtccg gagaaaagtc cgacgacgag tccggcaagc
    16081 catccgtttt ccgccctacg gcgaccgaca tcaccctgct gaccgccctg gtcgtcctca
    16141 acgtctttgt ggccgtctgg aacgaaaccc accaggaggg ccacccccgg tttggtccgt
    16201 gggcggggtt ggggttgcag gtggttgtgg tggtggtgtt gg
//
